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https://www.readbyqxmd.com/read/28644335/practice-bulletin-number-179-breast-cancer-risk-assessment-and-screening-in-average-risk-women
#1
(no author information available yet)
Breast cancer is the most commonly diagnosed cancer in women in the United States and the second leading cause of cancer death in American women (1). Regular screening mammography starting at age 40 years reduces breast cancer mortality in average-risk women (2). Screening, however, also exposes women to harm through false-positive test results and overdiagnosis of biologically indolent lesions. Differences in balancing benefits and harms have led to differences among major guidelines about what age to start, what age to stop, and how frequently to recommend mammography screening in average-risk women (2-4)...
July 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28644328/practice-bulletin-no-179-summary-breast-cancer-risk-assessment-and-screening-in-average-risk-women
#2
(no author information available yet)
Breast cancer is the most commonly diagnosed cancer in women in the United States and the second leading cause of cancer death in American women (1). Regular screening mammography starting at age 40 years reduces breast cancer mortality in average-risk women (2). Screening, however, also exposes women to harm through false-positive test results and overdiagnosis of biologically indolent lesions. Differences in balancing benefits and harms have led to differences among major guidelines about what age to start, what age to stop, and how frequently to recommend mammography screening in average-risk women (2-4)...
July 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28643746/breast-cancer-screening-practices-amongst-female-tertiary-health-worker-in-nnewi
#3
Chimezie Innocent Madubogwu, Amobi Ochonma Egwuonwu, Ngozi Ukamaka Madubogwu, Ifeoma A Njelita
BACKGROUND: Breast cancer in Nigeria and other developing countries is characterized by late presentation and poor outcome due to ignorance, superstition, self-denial, fear of mastectomy, and unavailability of treatment facilities. The mortality of breast cancer in Western world is decreasing due to early detection and better management. OBJECTIVE: This study aims at accessing the knowledge, attitude, and practice of breast cancer screening among female tertiary health workers...
April 2017: Journal of Cancer Research and Therapeutics
https://www.readbyqxmd.com/read/28643015/the-role-of-screening-mri-in-the-era-of-next-generation-sequencing-and-moderate-risk-genetic-mutations
#4
REVIEW
Sarah Macklin, Jennifer Gass, Ghada Mitri, Paldeep S Atwal, Stephanie Hines
With the advent of next-generation sequencing, the ability to rapidly analyze numerous genes simultaneously has led to the creation of large cancer gene panels. Some of these genes, like BRCA1 and BRCA2, have been heavily researched and have well-established management guidelines. Other more newly established genes, like ATM, CHEK2, and PALB2, have previously had less robust research surrounding them which has limited the ability to create accurate risk estimates. With their inclusion on gene panels, there has been more pressure to produce management guidelines for patients discovered to carry pathogenic variants in these genes...
June 22, 2017: Familial Cancer
https://www.readbyqxmd.com/read/28639832/comparing-diagnostic-performance-of-digital-breast-tomosynthesis-and-full-field-digital-mammography-in-a-hybrid-screening-environment
#5
Catherine S Giess, Sarvenaz Pourjabbar, Ivan K Ip, Ronilda Lacson, Emily Alper, Ramin Khorasani
OBJECTIVE: The purpose of this study is to compare the diagnostic performance of screening digital breast tomosynthesis (DBT) to that of full-field digital mammography (FFDM) in a mixed DBT and FFDM imaging environment. MATERIALS AND METHODS: This retrospective observational study consisted of all female patients undergoing screening DBT or FFDM at an academic medical center and outpatient imaging facility between October 2012 and May 2015. Patient demographics and personal history of breast cancer were collected from the electronic medical record...
June 22, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28630214/patient-derived-interstitial-fluids-and-predisposition-to-aggressive-sporadic-breast-cancer-through-collagen-remodeling-and-inactivation-of-p53
#6
Timothy Kenny, Hank Schmidt, Kerin Adelson, Yujin Hoshida, Anna P Koh, Nagma Shah, John P Mandeli, Jess Ting, Doris Germain
Despite the fact that interstitial fluid (IF) represents a third of our body fluid, it is the most poorly understood body fluid in medicine. Increased IF pressure is thought to result from the increased deposition of extracellular matrix in the affected tissue preventing its reabsorption. In the cancer field, increased rigidity surrounding a cancerous mass remains the main reason that palpation and radiological examination, such as mammography, are used for cancer detection. While the pressure produced by IF has been considered, the biochemical composition of IF has not been considered in its effect on tumors...
June 19, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28629329/personalised-informed-choice-on-evidence-and-controversy-on-mammography-screening-study-protocol-for-a-randomized-controlled-trial
#7
Anna Roberto, Cinzia Colombo, Giulia Candiani, Livia Giordano, Paola Mantellini, Eugenio Paci, Roberto Satolli, Mario Valenza, Paola Mosconi
BACKGROUND: In Italy women aged 50-69 are invited for a population-based breast cancer (BC) screening. Physicians, policy makers and patients associations agree on the need to inform women about the benefits and harms in order to permit an informed decision. Decision aids (DA) are an effective way to support people in their decisions about health. This trial aims to assess women's informed choices, according to their health literacy and values, on participating or not in BC screening for the first time...
June 19, 2017: BMC Cancer
https://www.readbyqxmd.com/read/28627297/a-bayesian-simulation-model-for-breast-cancer-screening-incidence-treatment-and-mortality
#8
Xuelin Huang, Yisheng Li, Juhee Song, Donald A Berry
BACKGROUND: The important but complicated research questions regarding the optimization of mammography screening for the detection of breast cancer are unable to be answered through any single trial or a simple meta-analysis of related trials. The Cancer Intervention and Surveillance Network (CISNET) breast groups provide answers using complex statistical models to simulate population dynamics. Among them, the MD Anderson Cancer Center (Model M) takes a unique approach by not making any assumptions on the natural history of breast cancer, such as the distribution of the indolent time before detection, but simulating only the observable part of a woman's disease and life...
June 1, 2017: Medical Decision Making: An International Journal of the Society for Medical Decision Making
https://www.readbyqxmd.com/read/28624977/interaction-of-mammographic-breast-density-with-menopausal-status-and-postmenopausal-hormone-use-in-relation-to-the-risk-of-aggressive-breast-cancer-subtypes
#9
Lusine Yaghjyan, Rulla M Tamimi, Kimberly A Bertrand, Christopher G Scott, Matthew R Jensen, V Shane Pankratz, Kathy Brandt, Daniel Visscher, Aaron Norman, Fergus Couch, John Shepherd, Bo Fan, Yunn-Yi Chen, Lin Ma, Andrew H Beck, Steven R Cummings, Karla Kerlikowske, Celine M Vachon
PURPOSE: We examined the associations of mammographic breast density with breast cancer risk by tumor aggressiveness and by menopausal status and current postmenopausal hormone therapy. METHODS: This study included 2596 invasive breast cancer cases and 4059 controls selected from participants of four nested case-control studies within four established cohorts: the Mayo Mammography Health Study, the Nurses' Health Study, Nurses' Health Study II, and San Francisco Mammography Registry...
June 17, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/28621548/an-investigation-into-the-mammographic-appearances-of-missed-breast-cancers-when-recall-rates-are-reduced
#10
Norhashimah Mohd Norsuddin, Claudia Mello-Thoms, Warren Reed, Mary Rickard, Sarah Lewis
OBJECTIVES: This study investigated whether certain mammographic appearances of breast cancer are missed when radiologists read at lower recall rates. METHODS: Five radiologists read one identical test set of 200 mammographic (180 normal cases and 20 abnormal cases) three times and were requested to adhere to three different recall rate conditions: free recall, 15% and 10%. The radiologists were asked to mark the locations of suspicious lesions and provide a confidence rating for each decision...
June 16, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28619739/renal-cell-carcinoma-with-isolated-breast-metastasis
#11
Sarah M Dhannoon, Ali A Alsaad, Abdo R Asmar, Fuad H Shahin
Renal cell carcinoma (RCC) is a highly prevalent disease worldwide with many cases being metastasised to various organs during the time of initial presentation. Metastatic RCC to the breast is a rare entity and can mimic primary breast carcinoma. In this article, we present a 63-year-old Caucasian woman presented with a breast mass that was detected by screening mammography and found to have a biopsy proven grade-II clear RCC in the breast tissue. Despite the high incidence and prevalence of primary breast cancer, metastasis from extramammary should be suspected in patients with a prior history of other cancers...
June 15, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28614990/screening-organization-and-recall-rate-in-a-regional-breast-screening-programme
#12
Tina Beruchashwili, Rema Gvamichava, Stephen W Duffy
Objective To use results on recall rates from a regional non-population-based breast screening programme to inform practice in a planned national population-based programme. Methods We analysed data on rates of recall for further assessment in 27,327 mammographic screening episodes in 2015-2016 in the breast screening programme in the city of Tbilisi, Georgia. Screening was done by two-view digital mammography with double reading in women aged 40-70, and further assessment took place at the same clinic and during the same visit as the initial screening mammogram...
January 1, 2017: Journal of Medical Screening
https://www.readbyqxmd.com/read/28612666/igg4-related-sclerosing-disease-of-the-breast-in-a-male-patient
#13
Taisia Vitkovski, Galina S Marder, Dominic A Filardi, Ekta Gupta, Frank Breuer
IgG4-related sclerosing disease of the breast is a rare entity with 10 reports in the literature. We report the first case in a male patient. A 48-year-old male presented with 4-week history of palpable right upper outer quadrant breast mass associated with skin puckering. He reported a family history of breast cancer in his aunt. Ultrasound and mammography showed a spiculated 2.5-cm mass associated with skin retraction with extension to the pectoralis muscle. Ultrasound-guided core biopsy was performed. The findings were interpreted as acute and chronic inflammatory process...
June 1, 2017: International Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28612325/stages-of-change-for-mammography-among-mexican-women-and-a-decisional-balance-comparison-across-countries
#14
Ana María Salinas-Martínez, David Emmanuel Castañeda-Vásquez, Norma Guadalupe García-Morales, Norma Edith Oliva-Sosa, Laura Hermila de-la-Garza-Salinas, Georgina Mayela Núñez-Rocha, José Manuel Ramírez-Aranda
An analysis of the adoption of secondary preventive behaviors is significant in regions with disparities in mammography use and breast cancer survival. Therefore, we determined the cognitive factors and the degree to which they differentiate stages of change in mammography among Mexican women. We also compared the decisional balance performance at Mexico, Switzerland, South Korea, and the USA. A cross-sectional study was designed for women in the stages of precontemplation (n = 240), contemplation (n = 243), action (n = 205), maintenance (n = 311), and relapse (n = 348)...
June 14, 2017: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/28611851/acceleration-of-image-segmentation-algorithm-for-breast-mammogram-images-using-high-performance-reconfigurable-dataflow-computers
#15
Ivan L Milankovic, Nikola V Mijailovic, Nenad D Filipovic, Aleksandar S Peulic
Image segmentation is one of the most common procedures in medical imaging applications. It is also a very important task in breast cancer detection. Breast cancer detection procedure based on mammography can be divided into several stages. The first stage is the extraction of the region of interest from a breast image, followed by the identification of suspicious mass regions, their classification, and comparison with the existing image database. It is often the case that already existing image databases have large sets of data whose processing requires a lot of time, and thus the acceleration of each of the processing stages in breast cancer detection is a very important issue...
2017: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/28610472/incidental-breast-carcinoma-in-reduction-mammoplasty
#16
Michaël Huysmans, Marc Bronckaers, Charlotte Schillebeeckx, Dirk Servaes
AIM: The objective of this study was to analyze the incidence and treatment options of occult cancer or atypical lesions found in the histopathological examination of reduction mammoplasty (RM) specimens. The role of preoperative mammography and systematic histopathological examination are discussed. METHODS: We performed a retrospective single-center database review of all patients who underwent a RM between January 2005 and December 2014. Preoperative examination, histopathological findings and follow-up were documented...
June 13, 2017: Acta Chirurgica Belgica
https://www.readbyqxmd.com/read/28609204/surveillance-of-women-with-the-brca1-or-brca2-mutation-by-using-biannual-automated-breast-us-mr-imaging-and-mammography
#17
Jan C M van Zelst, Roel D M Mus, Gwendolyn Woldringh, Matthieu J C M Rutten, Peter Bult, Suzan Vreemann, Mathijn de Jong, Nico Karssemeijer, Nicoline Hoogerbrugge, Ritse M Mann
Purpose To evaluate a multimodal surveillance regimen including yearly full-field digital (FFD) mammography, dynamic contrast agent-enhanced (DCE) magnetic resonance (MR) imaging, and biannual automated breast (AB) ultrasonography (US) in women with BRCA1 and BRCA2 mutations. Materials and Methods This prospective multicenter trial enrolled 296 carriers of the BRCA mutation (153 BRCA1 and 128 BRCA2 carriers, and 15 women with first-degree untested relatives) between September 2010 and November 2012, with follow-up until November 2015...
June 13, 2017: Radiology
https://www.readbyqxmd.com/read/28609163/imaging-appearance-and-clinical-impact-of-preoperative-breast-mri-in-pregnancy-associated-breast-cancer
#18
Kelly S Myers, Lauren A Green, Lizza Lebron, Elizabeth A Morris
OBJECTIVE: The purpose of this study is to describe the imaging features of pregnancy-associated breast cancer (PABC) on breast MRI and to consider the impact of preoperative MRI on patient management. MATERIALS AND METHODS: A retrospective review of medical records from January 1994 to May 2014 identified 183 women who presented with a new diagnosis of breast cancer during pregnancy or within 1 year postpartum. MR images were available for 53 of these patients, all of whom were included in the study...
June 13, 2017: AJR. American Journal of Roentgenology
https://www.readbyqxmd.com/read/28605115/interventions-promoting-breast-cancer-screening-among-turkish-women-with-global-implications-a-systematic-review
#19
Selda Secginli, Nursen O Nahcivan, Gussun Gunes, Ritin Fernandez
BACKGROUND: Breast cancer is a major health concern and remains the most common malignancy in women worldwide and in Turkey. Mammography, clinical breast examination (CBE), and breast self-examination (BSE) are recommended methods to detect early breast cancer in women. Many strategies have been developed to increase the rates of mammography, CBE, and BSE among Turkish women. Despite the benefits of breast cancer screening, these modalities are still underutilized by the majority of Turkish women...
June 12, 2017: Worldviews on Evidence-based Nursing
https://www.readbyqxmd.com/read/28603859/disparities-in-abnormal-mammogram-follow-up-time-for-asian-women-compared-with-non-hispanic-white-women-and-between-asian-ethnic-groups
#20
Kim H Nguyen, Rena J Pasick, Susan L Stewart, Karla Kerlikowske, Leah S Karliner
BACKGROUND: Delays in abnormal mammogram follow-up contribute to poor outcomes. In the current study, the authors examined differences in abnormal screening mammogram follow-up between non-Hispanic white (NHW) and Asian women. METHODS: The authors used a prospective cohort of NHW and Asian women with a Breast Imaging, Reporting and Data System (BI-RADS) abnormal result of category 0 or 3-plus in the San Francisco Mammography Registry between 2000 and 2010. Kaplan-Meier estimation for the median number of days to follow-up with a diagnostic radiologic test was performed, and the authors compared the percentage of women with follow-up at 30 days, 60 days, and 90 days and no follow-up at 1 year for Asian women overall (and Asian ethnic groups) and NHW women...
June 12, 2017: Cancer
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