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AIDS & skin

Marise Ramos de Souza, Waldemar Naves do Amaral, Rafael Alves Guimarães, Giovanni Rezza, Sandra Maria Brunini
BACKGROUND: The purpose of this study was to estimate the prevalence and examine the factors associated with reproductive desire among women living with HIV/AIDS (WLWHA) in Central Brazil. METHODS: A cross-sectional study involving 274 WLWHA, aged 18 to 49 years, was conducted with the support of treatment services and non-governmental organizations that assist people living with HIV/AIDS. Data regarding sociodemographic characteristics, substance use, sexual behavior, and reproductive variables were collected through interviews...
2017: PloS One
Jack Burdick, Oge Marques, Janet Weinthal, Borko Furht
Melanoma is a fatal form of skin cancer when left undiagnosed. Computer-aided diagnosis systems powered by convolutional neural networks (CNNs) can improve diagnostic accuracy and save lives. CNNs have been successfully used in both skin lesion segmentation and classification. For reasons heretofore unclear, previous works have found image segmentation to be, conflictingly, both detrimental and beneficial to skin lesion classification. We investigate the effect of expanding the segmentation border to include pixels surrounding the target lesion...
October 18, 2017: Journal of Digital Imaging: the Official Journal of the Society for Computer Applications in Radiology
Yuqing Tan, Sam K C Chang
Channel catfish skin is a by-product from catfish fillet production. Collagens were extracted from catfish skins by: (1) acid; (2) homogenization-aided; and (3) pepsin-aided extraction methods. Kinetic analysis of extraction was performed. SDS-PAGE was carried out for all collagens extracted under different conditions. Protein solubility, zeta potential, circular dichroism and gel strength of the collagen extracted by three methods were studied to determine optimal extraction conditions. Protein recovery rate from minced skins extracted with pH 2...
March 1, 2018: Food Chemistry
Geraldine Kyle
Chronic lymphocytic leukaemia (CLL) is a non-Hodgkin lymphoma commonly occurring in older adults. Many people with CLL can go for years without requiring treatment. However, they have an increased risk of secondary cancers, specifically melanoma and non-melanoma skin cancers. Furthermore, these secondary cancers are frequently more aggressive in this cohort of patients. Health professionals working in haematology, dermatology and general practice have an opportunity to educate patients about risk factors and measures to aid prevention...
October 12, 2017: British Journal of Nursing: BJN
D Reissis, T Tickunas, R A Agha, Avh Greig
Recurrent keloid scarring has a significant impact on quality of life. Management is complex, particularly for scars resistant to conventional treatments and in paediatric cases where radiotherapy is not a suitable adjunct to surgical excision. We present the case of a nine-year-old African Caribbean girl with multiple large and recurrent keloid scars on both ears and bilateral sensorineural deafness. Following repeated intralesional excisions, corticosteroid and botulinum toxin injections, she continued to experience rapid recurrence of her keloids, worsening pain and pruritus...
September 15, 2017: Annals of the Royal College of Surgeons of England
Puskar Shyam Chowdhury, Prasant Nayak, Deepak David, Sujata Mallick
INTRODUCTION: A precise puncture of the renal collecting system is the most essential step for percutaneous nephrolithotomy (PCNL). There are many techniques describing this crucial first step in PCNL including the bull's eye technique, triangulation technique, free-hand technique, and gradual descensus technique. We describe a novel puncture guide to assist accurate percutaneous needle placement during bull's eye technique. METHODS: The mini access guide (MAG) stabilizes the initial puncture needle by mounting it on an adjustable multidirectional carrier fixed to the patient's skin, which aids in achieving the "bull's eye" puncture...
October 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
Tushar Patial, Girish Sharma, Pamposh Raina
BACKGROUND: Traumatic amputation of the penis is a rare surgical emergency. Although repair techniques have been well described in literature, failure of replantation and its causes are poorly understood and reported. Herein, we report the case of a 9 year old boy who underwent replantation of his amputated penis with delayed failure of the surgery, along with a discussion of recent advances in the management of this condition. CASE  PRESENTATION: A 9-year-old boy was referred to our hospital for traumatic amputation of the penis...
October 10, 2017: BMC Urology
Francesca Sorgini, Renato Caliò, Maria Chiara Carrozza, Calogero Maria Oddo
PURPOSE: The aim of this review is to analyze haptic sensory substitution technologies for deaf, blind and deaf-blind individuals. METHOD: The literature search has been performed in Scopus, PubMed and Google Scholar databases using selected keywords, analyzing studies from 1960s to present. Search on databases for scientific publications has been accompanied by web search for commercial devices. Results have been classified by sensory disability and functionality, and analyzed by assistive technology...
October 10, 2017: Disability and Rehabilitation. Assistive Technology
Albenise Santana Alves Barros, Helison Oliveira Carvalho, Igor Victor Ferreira Dos Santos, Talisson Taglialegna, Tafnis Ingret Dos Santos Sampaio, Jonatas Lobato Duarte, Caio Pinho Fernandes, José Carlos Tavares Carvalho
INTRODUCTION: Portulaca pilosa L., belonging to the family Portulacaceae, is a common herbaceous plant in the Americas and in the Amazon, is popularly known as love-grown and is traditionally used as an aid in the treatment of burns, buds, insect bites and wound healing. This study aims to evaluate the non-clinical topical healing activity of the P. pilosa gel (GPP) and the propyleneglycol extract of P. pilosa (EPP) in Wistar rats. METHODS: For the healing activity, wistar rats were divided into the following groups: negative control (GVE - vehicle, 150mg/kg), positive control (Fibrinase(®)- FIB, 100U/kg), Portulaca pilosa gel 10%, (GPP, 150mg/kg), and propylenglycollic extract of Portulaca pilosa (EPP, 150 mg/kg), which were submitted to a surgical procedure to obtain the wounds, and were treated topically for 7days...
October 4, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
Maja Šikić Pogačar, Uroš Maver, Nataša Marčun Varda, Dušanka Mičetić-Turk
Diaper dermatitis is the most common inflammatory skin eruption within the diaper area in infants and toddlers. Although it rarely causes problems for prolonged periods of time, it causes considerable distress for both infants and parents. Diapered skin is exposed to friction, excessive hydration, varying pH, and is in constant contact with urine and feces, both of which are highly irritant to the skin. The three most common types of diaper dermatitis include chaffing dermatitis, irritant contact dermatitis, and diaper candidiasis...
October 6, 2017: International Journal of Dermatology
Anujit Sarkar, Madhusudan R Nandineni
OBJECTIVES: Human skin color is one of the most conspicuously variable physical traits that has attracted the attention of physical anthropologists, social scientists and human geneticists. Although several studies have established the underlying genes and their variants affecting human skin color, they were mostly confined to Europeans and Africans and similar studies in Indian populations have been scanty. Studying the association between candidate genetic variants and skin color will help to validate previous findings and to better understand the molecular mechanism of skin color variation...
October 6, 2017: American Journal of Human Biology: the Official Journal of the Human Biology Council
Gabrielle L McLemore, Salih Toker, Zainab Boone-Kukoyi, Hillary Ajifa, Carisse Lansiquot, Chinenye Nwawulu, Stanley Onyedum, Bridgit M Kioko, Kadir Aslan
Gout is a disease with elusive treatment options. Reduction of the size of l-alanine crystals as a model crystal for gouty tophi with the use of a monomode solid-state microwave was examined as a possible therapeutic aid. The effect of microwave heating on l-alanine crystals in the presence of gold nanoparticles (Au NPs) in solution and synovial fluid (SF) in a plastic pouch through a synthetic skin patch was investigated. In this regard, three experimental paradigms were employed: Paradigm 1 includes the effect of variable microwave power (5-10 W) and variable heating time (5-60 s) and Au NPs in water (20 nm size, volume of 10 μL) in a plastic pouch (1 × 2 cm(2) in size)...
September 30, 2017: ACS Omega
Keshavamurthy Vinay, Anuradha Bishnoi, Davinder Parsad, Uma N Saikia, Muthu Sendhil Kumaran
BACKGROUND: Acquired dermal macular hyperpigmentation (ADMH) is a hypernym encompassing Riehl's melanosis, lichen planus pigmentosus, and ashy dermatoses that show significant clinicopathological overlap. We sought to describe the dermatoscopic features of ADMH and correlate them with histopathological findings. METHODS: This was a prospective observational study performed in two phases. A detailed clinical and dermatoscopic examination was performed, and skin biopsies were obtained in 51 patients...
October 3, 2017: International Journal of Dermatology
Michael A Marchetti, Noel C F Codella, Stephen W Dusza, David A Gutman, Brian Helba, Aadi Kalloo, Nabin Mishra, Cristina Carrera, M Emre Celebi, Jennifer L DeFazio, Natalia Jaimes, Ashfaq A Marghoob, Elizabeth Quigley, Alon Scope, Oriol Yélamos, Allan C Halpern
BACKGROUND: Computer vision may aid in melanoma detection. OBJECTIVE: We sought to compare melanoma diagnostic accuracy of computer algorithms to dermatologists using dermoscopic images. METHODS: We conducted a cross-sectional study using 100 randomly selected dermoscopic images (50 melanomas, 44 nevi, and 6 lentigines) from an international computer vision melanoma challenge dataset (n = 379), along with individual algorithm results from 25 teams...
September 29, 2017: Journal of the American Academy of Dermatology
Maxim Gleser, Frank Schwab, Philipp Solbach, Ralf-Peter Vonberg
BACKGROUND: Non-sterile gloves primarily serve as a barrier protection for health care workers (HCWs). However, pathogens may often contaminate the skin of HCWs during glove removal; therefore, pathogens may be further transmitted and cause nosocomial infections. METHODS: A field study was conducted comparing contamination rates when using standard gloves or a new modified product equipped with an additional flap (doffing aid) for easier removal. Gloves were removed after bathing gloved hands in an artificial fluorescent lotion...
September 26, 2017: American Journal of Infection Control
Deepak Pemmaraju, Tejaswini Appidi, Gillipsie Minhas, Surya Prakash Singh, Nooruddin Khan, Mahadeb Pal, Rohit Srivastava, Aravind Kumar Rengan
Development of multifunctional biodegradable nanomaterials to encapsulate hydrophobic drugs and their triggered release in cancer theranostics is a challenge. In the current study, we report the encapsulation of potent anticancer - chlorophyll rich biomolecular fraction from the plant Anthocephalus cadamba into a polymeric nanosystem. The biomolecular fraction was combined with an NIR dye IR-780 to make it photo-thermally active. It was evaluated for its combinatorial (biomolecular extract and photothermal mediated) synergistic cytotoxicity in skin cancer cells...
September 27, 2017: International Journal of Biological Macromolecules
Ivo Dobrev, Jae Hoon Sim, Stefan Stenfelt, Sebastian Ihrle, Rahel Gerig, Flurin Pfiffner, Albrecht Eiber, Alexander M Huber, Christof Röösli
BACKGROUND: Bone conduction (BC) is an alternative to air conduction to stimulate the inner ear. In general, the stimulation for BC occurs on a specific location directly on the skull bone or through the skin covering the skull bone. The stimulation propagates to the ipsilateral and contralateral cochlea, mainly via the skull bone and possibly via other skull contents. This study aims to investigate the wave propagation on the surface of the skull bone during BC stimulation at the forehead and at ipsilateral mastoid...
September 23, 2017: Hearing Research
Brian Boyd, Carlos A Zamora, Mauricio Castillo
Adverse reactions to iodinated and gadolinium-based contrast agents occur at an incidence of less than 1%. Although the exact pathophysiologic mechanisms are not completely understood, the treatment regimens are well accepted. Skin testing may be helpful in patients with a history of severe allergiclike reaction to aid in the selection of alternative contrast agents. Premedication should only be used for a history of allergiclike reaction. Imaging team members should be familiar with signs and symptoms of contrast reactions to allow for prompt assessment and treatment...
November 2017: Magnetic Resonance Imaging Clinics of North America
Michiko Matsushita, Takeshi Iwasaki, Daisuke Nonaka, Satoshi Kuwamoto, Keiko Nagata, Masako Kato, Yukisato Kitamura, Kazuhiko Hayashi
BACKGROUND: Merkel cell carcinomas (MCCs), clinically aggressive neuroendocrine skin cancers, are divided into Merkel cell polyomavirus (MCPyV)-positive and -negative tumors, which show different clinicopathological features and may develop through different mechanisms of carcinogenesis. Aberrant expression of activation-induced cytidine deaminase (AID) as a genomic modulator was demonstrated through pathogen-related NF-κB signal in Helicobacter pylori-associated gastric cancer, adult T cell leukemia/lymphoma (HTLV-1), hepatoma (HCV), and Burkitt lymphoma (EBV)...
September 2017: Yonago Acta Medica
Sanjairaj Vijayavenkataraman, Zhang Shuo, Jerry Y H Fuh, Wen Feng Lu
Tissue engineering is a multi-disciplinary area of research bringing together the fields of engineering and life sciences with the aim of fabricating tissue constructs aiding in the regeneration of damaged tissues and organs. Scaffolds play a key role in tissue engineering, acting as the templates for tissue regeneration and guiding the growth of new tissue. The use of stem cells in tissue engineering and regenerative medicine becomes indispensable, especially for applications involving successful long-term restoration of continuously self-renewing tissues, such as skin...
July 27, 2017: Bioengineering
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