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https://www.readbyqxmd.com/read/27917977/discontinuity-in-pastoral-development-time-to-update-the-method
#1
S KrÄtli
Most off-the-shelf basic methodological tools currently used in pastoral development (e.g. technical definitions and conventional scales of observation) retain underlying assumptions about stability and uniformity being the norm (i.e. 'equilibrium thinking'). Such assumptions reflect a theoretical framework which had been questioned since the 1970s and was openly disproved in scientific circles during the 1990s, when it was shown to be fundamentally inadequate. Today, lingering equilibrium assumptions in the methodological legacy of pastoral development get in the way of operationalising state-of-the-art understanding of pastoral systems and drylands...
November 2016: Revue Scientifique et Technique
https://www.readbyqxmd.com/read/27911401/an-optimized-protocol-to-analyze-glycolysis-and-mitochondrial-respiration-in-lymphocytes
#2
Javier Traba, Pietro Miozzo, Billur Akkaya, Susan K Pierce, Munir Akkaya
Lymphocytes respond to a variety of stimuli by activating intracellular signaling pathways, which in turn leads to rapid cellular proliferation, migration and differentiation, and cytokine production. All of these events are tightly linked to the energy status of the cell, and therefore studying the energy-producing pathways may give clues about the overall functionality of these cells. The extracellular flux analyzer is a commonly used device for evaluating the performance of glycolysis and mitochondrial respiration in many cell types...
November 21, 2016: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/27904025/early-raas-blockade-exerts-renoprotective-effects-in-autosomal-recessive-alport-syndrome
#3
Nao Uchida, Naonori Kumagai, Kandai Nozu, Xue Jun Fu, Kazumoto Iijima, Yoshiaki Kondo, Shigeo Kure
Alport syndrome is a progressive renal disease caused by mutations in COL4A3, COL4A4, and COL4A5 genes that encode collagen type IV alpha 3, alpha 4, and alpha 5 chains, respectively. Because of abnormal collagen chain, glomerular basement membrane becomes fragile and most of the patients progress to end-stage renal disease in early adulthood. COL4A5 mutation causes X-linked form of Alport syndrome, and two mutations in either COL4A3 or COL4A4 causes an autosomal recessive Alport syndrome. Recently, renin-angiotensin-aldosterone system (RAAS) blockade has been shown to attenuate effectively disease progression in Alport syndrome...
2016: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/27886481/correlation-between-fragility-and-the-arrhenius-crossover-phenomenon-in-metallic-molecular-and-network-liquids
#4
Abhishek Jaiswal, Takeshi Egami, K F Kelton, Kenneth S Schweizer, Yang Zhang
We report the observation of a distinct correlation between the kinetic fragility index m and the reduced Arrhenius crossover temperature θ_{A}=T_{A}/T_{g} in various glass-forming liquids, identifying three distinguishable groups. In particular, for 11 glass-forming metallic liquids, we universally observe a crossover in the mean diffusion coefficient from high-temperature Arrhenius to low-temperature super-Arrhenius behavior at approximately θ_{A}≈2 which is in the stable liquid phases. In contrast, for fragile molecular liquids, this crossover occurs at much lower θ_{A}≈1...
November 11, 2016: Physical Review Letters
https://www.readbyqxmd.com/read/27885593/campylobacter-jejuni-isolation-enumeration-from-environmental-samples
#5
Kelli L Hiett
Currently, there is no universally accepted standard media or method for the recovery of Campylobacter species. This is likely due to the ubiquity of the organism in nature, the complex sample matrices from which the organism is often recovered, as well as the fragile/viable-but nonculturable state the organism assumes in response to stress. The use of a sterile filter placed upon a nonselective Brucella Agar Blood Plate (BAB), followed by incubation at 37 °C in a hydrogen-containing atmosphere (Campycheck), is one method to recover stressed and emerging Campylobacter spp...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27859148/11-september-an-attack-at-the-limits-of-thought
#6
Roberta Patalano
The paper deals with imagination and its failures from a psychoanalytic perspective. We offer a definition of imagination failures and suggest how they can be interpreted as an opportunity to learn from experience. In order to show that the topic has a concrete and not only speculative significance we consider the public report on September 11 as a case study. The report was published by the National Commission on Terrorist Attacks Upon the United States after a long investigation of the facts and circumstances relating to the September 11 attacks...
November 17, 2016: International Journal of Psycho-analysis
https://www.readbyqxmd.com/read/27858282/improving-mental-health-outcomes-of-burmese-migrant-and-displaced-children-in-thailand-a-community-based-randomized-controlled-trial-of-a-parenting-and-family-skills-intervention
#7
Jeannie Annan, Amanda Sim, Eve S Puffer, Carmel Salhi, Theresa S Betancourt
: The negative effects of displacement and poverty on child mental health are well-known, yet research on prevention interventions in low- and middle-income countries, especially fragile states, remains limited. We examined the effectiveness of a parenting skills intervention on mental health outcomes among Burmese migrant and displaced children living in 20 communities in Thailand. Participants were primary caregivers and children aged 7 to 15 years (n = 479 families). Families were randomly assigned to receive an adapted version of the Strengthening Families Program (n = 240) or a wait-list control condition (n = 239)...
November 17, 2016: Prevention Science: the Official Journal of the Society for Prevention Research
https://www.readbyqxmd.com/read/27854443/puffed-up-but-shaky-selves-state-self-esteem-level-and-variability-in-narcissists
#8
Katharina Geukes, Steffen Nestler, Roos Hutteman, Michael Dufner, Albrecht C P Küfner, Boris Egloff, Jaap J A Denissen, Mitja D Back
Different theoretical conceptualizations characterize grandiose narcissists by high, yet fragile self-esteem. Empirical evidence, however, has been inconsistent, particularly regarding the relationship between narcissism and self-esteem fragility (i.e., self-esteem variability). Here, we aim at unraveling this inconsistency by disentangling the effects of two theoretically distinct facets of narcissism (i.e., admiration and rivalry) on the two aspects of state self-esteem (i.e., level and variability). We report on data from a laboratory-based and two field-based studies (total N = 596) in realistic social contexts, capturing momentary, daily, and weekly fluctuations of state self-esteem...
November 17, 2016: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/27836256/robust-passive-control-for-a-class-of-uncertain-neutral-systems-based-on-sliding-mode-observer
#9
Zhen Liu, Lin Zhao, Yonggui Kao, Cunchen Gao
The passivity-based sliding mode control (SMC) problem for a class of uncertain neutral systems with unmeasured states is investigated. Firstly, a particular non-fragile state observer is designed to generate the estimations of the system states, based upon which a novel integral-type sliding surface function is established for the control process. Secondly, a new sufficient condition for robust asymptotic stability and passivity of the resultant sliding mode dynamics (SMDs) is obtained in terms of linear matrix inequalities (LMIs)...
November 8, 2016: ISA Transactions
https://www.readbyqxmd.com/read/27821102/the-osteoporotic-fracture-prevention-program-in-rural-areas-ofra-a-protocol-for-a-cluster-randomized-health-care-fund-driven-intervention-in-a-routine-health-care-setting
#10
Kilian Rapp, Karin Kampe, Patrick Roigk, Hella Kircheisen, Clemens Becker, Ivonne Lindlbauer, Hans-Helmut König, Dietrich Rothenbacher, Gisela Büchele
BACKGROUND: Fragility fractures are one of the leading causes for disability in old people. The main underlying mechanisms are osteoporosis and falls. Evidence-based measures to prevent either falls or fractures are available. However, coordinated preventive approaches combining bone health and fall prevention are rare. The objective of the study is to evaluate a health care fund driven program, which encourages insured persons to adhere to national guidelines regarding bone health and physical activity and falls prevention...
November 8, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27820831/scientific-wealth-in-middle-east-and-north-africa-productivity-indigeneity-and-specialty-in-1981-2013
#11
Afreen Siddiqi, Jonathan Stoppani, Laura Diaz Anadon, Venkatesh Narayanamurti
Several developing countries seek to build knowledge-based economies by attempting to expand scientific research capabilities. Characterizing the state and direction of progress in this arena is challenging but important. Here, we employ three metrics: a classical metric of productivity (publications per person), an adapted metric which we denote as Revealed Scientific Advantage (developed from work used to compare publications in scientific fields among countries) to characterize disciplinary specialty, and a new metric, scientific indigeneity (defined as the ratio of publications with domestic corresponding authors) to characterize the locus of scientific activity that also serves as a partial proxy for local absorptive capacity...
2016: PloS One
https://www.readbyqxmd.com/read/27816231/distribution-of-the-fmr1-gene-in-females-by-race-ethnicity-women-with-diminished-ovarian-reserve-versus-women-with-normal-fertility-swan-study
#12
Lisa M Pastore, Steven L Young, Ani Manichaikul, Valerie L Baker, Xin Q Wang, Joel S Finkelstein
OBJECTIVE: To study whether reported, but inconsistent, associations between the FMR1 CGG repeat lengths in the intermediate, high normal, or low normal range differentiate women diagnosed with diminished ovarian reserve (DOR) from population controls and whether associations vary by race/ethnic group. DESIGN: Case-control study. SETTING: Academic and private fertility clinics. PATIENT(S): DOR cases (n = 129; 95 Whites, 22 Asian, 12 other) from five U...
November 2, 2016: Fertility and Sterility
https://www.readbyqxmd.com/read/27799058/next-generation-sequencing-and-a-novel-col3a1-mutation-associated-with-vascular-ehlers-danlos-syndrome-with-severe-intestinal-involvement-a-case-report
#13
Francesca Cortini, Barbara Marinelli, Manuela Seia, Barbara De Giorgio, Angela Cecilia Pesatori, Nicola Montano, Alessandra Bassotti
BACKGROUND: The vascular type of Ehlers-Danlos syndrome is an autosomal dominant connective tissue disorder caused by a mutation in the COL3A1 gene encoding pro-alpha1 chain of type III collagen. The vascular type of Ehlers-Danlos syndrome causes severe fragility of connective tissues with arterial and intestinal ruptures and complications in surgical and radiological treatments. CASE PRESENTATION: We present a case of a 38-year-old Italian woman who was diagnosed as having the vascular type of Ehlers-Danlos syndrome...
October 31, 2016: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/27783361/relationship-transitions-and-the-risk-for-child-maltreatment
#14
William Schneider
Family structure as a risk for child maltreatment has long been viewed as a static state in the child maltreatment literature. Drawing on data from the Fragile Families and Child Wellbeing Study, the author uses a series of individual fixed-effects models to investigate whether particular types of relationship transitions over children's first decade of life are associated with increased risk for maternal and paternal child abuse and maternal neglect. Findings question and confirm a number of long-standing theoretical and empirical findings from the child maltreatment literature...
December 2016: Demography
https://www.readbyqxmd.com/read/27782496/nanocerium-oxide-increases-the-survival-of-adult-rod-and-cone-photoreceptor-in-culture-by-abrogating-hydrogen-peroxide-induced-oxidative-stress
#15
Neelima Bhargava, Vellasamy Shanmugaiah, Manav Saxena, Manish Sharma, Niroj Kumar Sethy, Sushil Kumar Singh, Karuppiah Balakrishnan, Kalpana Bhargava, Mainak Das
In vitro cell culture system for adult rod and cone photoreceptor (PR) is an effective and economical model for screening drug candidates against all kinds of age related retinal blindness. Interestingly, adult PR cells have a limited survival in the culture system, thus preventing full exploitation of this in vitro approach for drug screening applications. The limited survival of the adult PR cells in culture is due to their inherently high oxidative stress and photic injury. Mixed valence-state ceria nanoparticles have the ability to scavenge free radicals and reduce oxidative stress...
September 16, 2016: Biointerphases
https://www.readbyqxmd.com/read/27782469/why-many-polymers-are-so-fragile-a-new-perspective
#16
C Dalle-Ferrier, A Kisliuk, L Hong, G Carini, G Carini, G D'Angelo, C Alba-Simionesco, V N Novikov, A P Sokolov
Many polymers exhibit much steeper temperature dependence of their structural relaxation time (higher fragility) than liquids of small molecules, and the mechanism of this unusually high fragility in polymers remains a puzzle. To reveal additional hints for understanding the underlying mechanism, we analyzed correlation of many properties of polymers to their fragility on example of model polymer polystyrene with various molecular weights (MWs). We demonstrate that these correlations work for short chains (oligomers), but fail progressively with increase in MW...
October 21, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/27773524/the-slow-relaxation-dynamics-in-the-amorphous-pharmaceutical-drugs-cimetidine-nizatidine-and-famotidine
#17
M Teresa Viciosa, Joaquim J Moura Ramos, Hermínio P Diogo
The slow molecular mobility in the amorphous solid state of 3 active pharmaceutical drugs (cimetidine, nizatidine, and famotidine) has been studied using differential scanning calorimetry and the 2 dielectric-related techniques of dielectric relaxation spectroscopy and thermally stimulated depolarization currents. The glass-forming ability, the glass stability, and the tendency for crystallization from the equilibrium melt were investigated by differential scanning calorimetry, which also provided the characterization of the main relaxation of the 3 glass formers...
October 20, 2016: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/27770800/does-cognitive-physical-screening-in-an-outpatient-setting-predict-institutionalization-after-hip-fracture
#18
Markus T Hongisto, Maria Nuotio, Tiina Luukkaala, Olli Väistö, Harri K Pihlajamäki
BACKGROUND: Institutionalization after hip fracture is a socio-economical burden. We examined the predictive value of Instrumental Activities of Daily Living (IADL) and Mini Mental State Examination (MMSE) for institutionalization after hip fracture to identify patients at risk for institutionalization. METHODS: Fragility hip fracture patients ≥65 years of age (n = 584) were comprehensively examined at a geriatric outpatient clinic 4 to 6 months after surgery and followed 1 year postoperatively...
October 22, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27756394/malaria-incidence-in-myanmar-2005-2014-steady-but-fragile-progress-towards-elimination
#19
Thet Thet Mu, Aye Aye Sein, Tint Tint Kyi, Myo Min, Ne Myo Aung, Nicholas M Anstey, Myat Phone Kyaw, Chit Soe, Mar Mar Kyi, Josh Hanson
BACKGROUND: There has been an impressive recent reduction in the global incidence of malaria, but the development of artemisinin resistance in the Greater Mekong Region threatens this progress. Increasing artemisinin resistance is particularly important in Myanmar, as it is the country in the Greater Mekong Region with the greatest malaria burden. If malaria is to be eliminated in the region, it is essential to define the spatial and temporal epidemiology of the disease in Myanmar to inform control strategies optimally...
October 18, 2016: Malaria Journal
https://www.readbyqxmd.com/read/27756140/in-response-to-the-editorial-sedation-in-endoscopy-in-2016-is-it-safe-sedation-with-propofol-led-by-the-endoscopist-in-complex-situations
#20
Manuel de la Matta
It is universally accepted that deep sedation involves more risks than light-to-moderate sedation. Deep sedation for endoscopic explorations is normally provided by anesthesiologists in Spain and in most countries of the European Unión. The present debate about deep sedation-anesthesia states goes beyond the topic of cardiovascular and respiratory adverse events, and targets the cognitive consequences and global increased mortality of uncontrolled sedation states, especially in specific fragile populations...
October 19, 2016: Revista Española de Enfermedades Digestivas
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