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https://www.readbyqxmd.com/read/28231251/empirical-lessons-regarding-contraception-in-a-protracted-refugee-setting-a-descriptive-study-from-maela-camp-on-the-thai-myanmar-border-1996-2015
#1
Somjet Srikanok, Daniel M Parker, Amber L Parker, Tracey Lee, Aung Myat Min, Pranee Ontuwong, Saw Oo Tan, Supachai Sirinonthachai, Rose McGready
Conflict settings and refugee camps can be chaotic places, with large and rapid population movements, exacerbated public health problems, and ad hoc health services. Reproductive health care that includes family planning is of heightened importance in such settings, however, funding and resources tend to be constrained and geared towards acute health services such as trauma management and infectious disease containment. Here we report on the complexities and challenges of providing family planning in a post-emergency refugee setting, using the example of the largest refugee camp on the Thai-Myanmar border, in existence now for over 30 years...
2017: PloS One
https://www.readbyqxmd.com/read/28230454/adherence-persistence-and-health-care-costs-for-patients-receiving-dipeptidyl-peptidase-4-inhibitors
#2
Karen L Rascati, Karen Worley, Yunus Meah, Damian Everhart
BACKGROUND: The dipeptidyl peptidase-4 (DPP-4) inhibitors are among the newer, yet more established, classes of diabetes medications. OBJECTIVE: To compare adherence, persistence, and health care costs among patients taking DPP-4 inhibitors. METHODS: Claims were extracted from Humana Medicare Advantage Prescription Drug (MAPD) or commercial plans for patients aged > 18 years with ≥ 1 prescription filled for a DPP-4 inhibitor between July 1, 2011, and March 31, 2013...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28230448/opioid-use-for-pain-management-after-implementation-of-a-medicaid-short-acting-opioid-quantity-limit
#3
Catherine S Riggs, Sarah J Billups, Samantha Flores, Rachana J Patel, Rachel M F Heilmann, Jessica L Milchak
BACKGROUND: The United States is currently experiencing an opioid abuse epidemic. Many policies and programs have been implemented at local, state, and national levels in an attempt to decrease prescription opioid addiction and overdose. On August 1, 2014, Colorado Medicaid implemented a policy change that limited the quantity of short-acting opioids (SAOs) that could be filled through the Medicaid benefit to no more than 4 tablets per day, or 120 tablets in 30 days. OBJECTIVE: To compare mean total daily dose (TDD) of opioids purchased by Kaiser Permanente Colorado (KPCO) Medicaid patients before and after implementation of the Medicaid SAO quantity limit...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28230447/effect-of-medicaid-policy-changes-on-medication-adherence-differences-by-baseline-adherence
#4
Krutika Amin, Joel F Farley, Matthew L Maciejewski, Marisa E Domino
BACKGROUND: In 2001, the North Carolina (NC) Medicaid program reduced the number of days prescription supply that enrollees could fill from 100 days to 34 days and increased copayments for brand-name medications. Previous work has shown that a change in these policies led to a decrease in medication adherence from 2.9 to 8.0 percentage points in specific populations with chronic conditions. Studies have also shown that days supply limits and copayment increases have heterogeneous effects based on enrollees' baseline characteristics, including baseline adherence...
March 2017: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/28230242/routine-port-site-excision-in-incidentally-discovered-gallbladder-cancer-is-not-associated-with-improved-survival-a-multi-institution-analysis-from-the-us-extrahepatic-biliary-malignancy-consortium
#5
Cecilia G Ethun, Lauren M Postlewait, Nina Le, Timothy M Pawlik, George Poultsides, Thuy Tran, Kamran Idrees, Chelsea A Isom, Ryan C Fields, Bradley A Krasnick, Sharon M Weber, Ahmed Salem, Robert C G Martin, Charles R Scoggins, Perry Shen, Harveshp D Mogal, Carl Schmidt, Eliza Beal, Ioannis Hatzaras, Rivfka Shenoy, Kenneth Cardona, Shishir K Maithel
BACKGROUND: Current data on the utility of port-site excision (PSE) during re-resection for incidentally discovered gallbladder cancer (IGBC) in the US are conflicting and limited to single-institution series. METHODS: All patients with IGBC who underwent curative re-resection at 10 institutions from 2000 to 2015 were included. Patients with and without PSE were compared. Primary outcome was overall survival (OS). RESULTS: Of 449 pts with GBC, 266 were incidentally discovered, of which 193(73%) underwent curative re-resection and had port-site data; 47 pts(24%) underwent PSE, 146(76%) did not...
February 23, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28224136/challenges-to-development-of-cervical-and-breast-cancer-program-development-in-post-conflict-liberia-presentation-prepared-for-african-first-ladies-conference-10th-scca-conference-addis-ababa-ethiopia-2016
#6
Ann Marie Beddoe
•Integrating cancer care in post-conflict settings.•Building health worker and infrastructure for cancer care in low resource setting.•Foreword by Her Excellency President Sirleaf, Republic of Liberia.
May 2017: Gynecologic Oncology Reports
https://www.readbyqxmd.com/read/28219374/the-right-to-health-of-non-nationals-and-displaced-persons-in-the-sustainable-development-goals-era-challenges-for-equity-in-universal-health-care
#7
EDITORIAL
Claire E Brolan, Lisa Forman, Stéphanie Dagron, Rachel Hammonds, Attiya Waris, Lyla Latif, Ana Lorena Ruano
INTRODUCTION: Under the Millennium Development Goals (MDGs), United Nations (UN) Member States reported progress on the targets toward their general citizenry. This focus repeatedly excluded marginalized ethnic and linguistic minorities, including people of refugee backgrounds and other vulnerable non-nationals that resided within a States' borders. The Sustainable Development Goals (SDGs) aim to be truly transformative by being made operational in all countries, and applied to all, nationals and non-nationals alike...
February 21, 2017: International Journal for Equity in Health
https://www.readbyqxmd.com/read/28218719/smart-device-use-and-perceived-physical-and-psychosocial-outcomes-among-hong-kong-adolescents
#8
Stephen Wai Hang Kwok, Paul Hong Lee, Regina Lai Tong Lee
Excessive electronic screen-based activities have been found to be associated with negative outcomes. The aim of this study was to investigate the prevalences and patterns of smart device activities and the purposes and perceived outcomes related to smart device use, and the differences in patterns of smart device activities between adolescents who did and did not perceive these outcomes. The study was a cross-sectional survey of Hong Kong primary and secondary school students. Demographic characteristics, purpose and pattern of the activities, and frequencies of the outcomes were measured...
February 18, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28216454/protective-effects-of-short-term-dietary-restriction-in-surgical-stress-and-chemotherapy
#9
REVIEW
Sebastian Brandhorst, Eylul Harputlugil, James R Mitchell, Valter D Longo
Reduced caloric intake including fasting, as well as the dietary composition or the timing of food intake impact longevity, likely through a modification in the onset or the severity of chronic aging-related diseases such as cancer. As with pre- and post-operative dietary recommendations, evidence-based nutritional advice from healthcare professionals during and after cancer treatment is often vague or conflicting. We hypothesize that preventive dietary recommendations can help in the context of both chronic cancer treatment efficacy and the avoidance of development of secondary malignancies, as well as in the context of protection from the acute stress of surgery...
February 16, 2017: Ageing Research Reviews
https://www.readbyqxmd.com/read/28215014/management-of-a-dutch-resident-barnacle-goose-branta-leucopsis-population-how-can-results-from-counts-ringing-and-hunting-bag-statistics-be-reconciled
#10
Henk P van der Jeugd, Anne Kwak
The resident Dutch Northern Delta barnacle geese Branta leucopsis population expanded steadily since birds first bred in 1982, increasing agricultural conflict. Derogation shooting has been used since 2005 to scare geese from sensitive crops and to reduce population size. Numbers almost doubled to ca. 28 000 individuals during 2007-2014, despite annual removal of 15-25% of geese and adult and juvenile survival rates of 79 and 67% (cf. natural survival of 96% for both age classes). Simple population modelling, using estimated annual survival values and fixed fecundity, predicted a moderate increase to 21 500 individuals in 2014...
March 2017: Ambio
https://www.readbyqxmd.com/read/28213669/aspirin-use-prior-to-coronary-artery-bypass-grafting-surgery-a-systematic-review
#11
REVIEW
Ayman Elbadawi, Marwan Saad, Ramez Nairooz
PURPOSE OF REVIEW: Aspirin use before coronary artery bypass graft (CABG) surgery has been a puzzling question for years. Controversy existed regarding the overall benefits vs. risk of pre-operative aspirin use and was translated to conflicting guidelines from major societies. RECENT FINDINGS: Observational studies have suggested a reduced mortality with pre-operative aspirin use. A meta-analysis of randomized controlled trials showed increased risk of post-operative bleeding with aspirin, with no associated increased mortality risk...
February 2017: Current Cardiology Reports
https://www.readbyqxmd.com/read/28211924/a-selfish-b-chromosome-induces-genome-elimination-by-disrupting-the-histone-code-in-the-jewel-wasp-nasonia-vitripennis
#12
John C Aldrich, Alexandra Leibholz, Manjinder S Cheema, Juan Ausiό, Patrick M Ferree
Intragenomic conflict describes a phenomenon in which genetic elements act 'selfishly' to gain a transmission advantage at the expense of the whole genome. A non-essential, selfish B chromosome known as Paternal Sex Ratio (PSR) induces complete elimination of the sperm-derived hereditary material in the jewel wasp Nasonia vitripennis. PSR prevents the paternal chromatin from forming chromosomes during the first embryonic mitosis, leading to its loss. Although paternally transmitted, PSR evades self-elimination in order to be inherited...
February 13, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28209554/when-war-is-better-than-peace-the-post-conflict-realities-of-children-born-of-wartime-rape-in-northern-uganda
#13
Myriam Denov, Atim Angela Lakor
This paper examines the realities and perspectives of a sample of 60 children born of wartime rape within the Lord's Resistance Army (LRA), and currently living in northern Uganda. These children were born to mothers who were abducted by the LRA, held captive for extended periods of time, repeatedly raped and impregnated. The paper explores the multiple challenges that these children face in the post-war period including, rejection, stigma, violence, socio-economic marginalization, and issues of identity and belonging...
February 13, 2017: Child Abuse & Neglect
https://www.readbyqxmd.com/read/28209529/menopausal-hormone-therapy-is-associated-with-increased-risk-of-fecal-incontinence-in-women-after-menopause
#14
Kyle Staller, Mary K Townsend, Hamed Khalili, Raaj Mehta, Francine Grodstein, William E Whitehead, Catherine A Matthews, Braden Kuo, Andrew T Chan
BACKGROUND & AIMS: Low estrogen levels could contribute to development of fecal incontinence (FI) in women after menopause by altering neuromuscular continence mechanisms. However, studies have produced conflicting results on the association between menopausal hormone therapy (MHT) and risk of FI. METHODS: We studied the association between MHT and risk of FI among 55,828 post-menopausal women (mean age 73 years) who participated in the Nurses' Health Study, enrolled since 2008, with no report of FI...
February 13, 2017: Gastroenterology
https://www.readbyqxmd.com/read/28206693/plasmid-and-clonal-interference-during-post-horizontal-gene-transfer-evolution
#15
S Bedhomme, D Perez Pantoja, I G Bravo
Plasmids are nucleic acid molecules that can drive their own replication in a living cell. They can be transmitted horizontally and can thrive in the host cell to high copy numbers. Plasmid replication and gene expression consume cellular resources and cells carrying plasmids incur fitness costs. But many plasmids carry genes that can be beneficial under certain conditions, allowing the cell to endure in the presence of antibiotics, toxins, competitors or parasites. Horizontal transfer of plasmid-encoded genes can thus instantaneously confer differential adaptation to local or transient selection conditions...
February 16, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28203146/insulin-like-growth-factor-1-at-the-crossroads-of-brain-development-and-aging
#16
REVIEW
Sarah Wrigley, Donia Arafa, Daniela Tropea
Insulin-like growth factor 1 (IGF1) is a polypeptide hormone structurally similar to insulin. It is central to the somatotropic axis, acting downstream of growth hormone (GH). It activates both the mitogen-activated protein (MAP) kinase and PI3K signaling pathways, acting in almost every tissue in the body to promote tissue growth and maturation through upregulation of anabolic processes. Overall GH and IGF1 signaling falls with age, suggesting that it is this reduced IGF1 activity that leads to age-related changes in organisms...
2017: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/28197634/sirt3-is-correlated-with-the-malignancy-of-non-small-cell-lung-cancer
#17
Yanlu Xiong, Mingxing Wang, Jinbo Zhao, Lei Wang, Xiaofei Li, Zhipei Zhang, Lintao Jia, Yong Han
The mitochondrial deacetylase SIRT3 plays a pivotal role in the initiation and the progression of certain cancers acting as an oncogene. However, in others it acts anti-oncogenically. Its conflicting action is possibly due to the different key proteins it modifies depending on the context of active intracellular signaling pathways in different cancers. SIRT3 is thus a novel target for preventing and treating cancer. In the present study, we explored the function of SIRT3 in non-small cell lung cancer (NSCLC) with the aim of elucidating the underlying mechanisms...
March 2017: International Journal of Oncology
https://www.readbyqxmd.com/read/28196952/revalidation-and-quality-assurance-the-application-of-the-musiq-framework-in-independent-verification-visits-to-healthcare-organisations
#18
Ann Griffin, Alex McKeown, Rowena Viney, Antonia Rich, Trevor Welland, Irene Gafson, Katherine Woolf
OBJECTIVES: We present a national evaluation of the impact of independent verification visits (IVVs) performed by National Health Service (NHS) England as part of quality assuring medical revalidation. Organisational visits are central to NHS quality assurance. They are costly, yet little empirical research evidence exists concerning their impact, and what does exist is conflicting. SETTING: The focus was on healthcare providers in the NHS (in secondary care) and private sector across England, who were designated bodies (DBs)...
February 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/28188757/cognitive-effects-of-androgen-deprivation-therapy-in-men-with-advanced-prostate-cancer
#19
Bulent Gunlusoy, Yasin Ceylan, Aslı Koskderlioglu, Muhtesem Gedizlioglu, Tansu Degirmenci, Pınar Ortan, Zafer Kozacioglu
OBJECTIVES: To evaluate prostate cancer effects of androgen deprivation therapy (ADT) by using a systematic set of methods to calculate specific cognitive functions in men with locally advanced or metastatic prostate cancer. METHODS: From April 2014 to February 2016, a prospective, comparative study was done to evaluate the cognitive effects of hormone therapy.Group 1 consisted of 78 patients with locally advanced or metastatic prostate cancer who received complete ADT treatment continously for 12 months and group 2 (control group) consisted of 78 patients who underwent radical prostatectomy without any additional treatment...
February 7, 2017: Urology
https://www.readbyqxmd.com/read/28185324/the-musculoskeletal-consequences-of-breast-reconstruction-using-the-latissimus-dorsi-muscle-for-women-following-mastectomy-for-breast-cancer-a-critical-review
#20
REVIEW
N E Blackburn, J G Mc Veigh, E Mc Caughan, I M Wilson
Breast reconstruction using the latissimus dorsi (LD) flap following mastectomy is an important management option in breast cancer. However, one common, but often ignored, complication following LD flap is shoulder dysfunction. The aim of this critical review was to comprehensively assess the musculoskeletal impact of LD breast reconstruction and evaluate the functional outcome following surgery. Five electronic databases were searched including; Medline, Embase, CINAHL Plus (Cumulative Index to Nursing and Allied Health), PubMed and Web of Science...
February 10, 2017: European Journal of Cancer Care
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