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Biomedical optics

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https://www.readbyqxmd.com/read/28214733/flexible-camphor-diamond-like-carbon-coating-on-polyurethane-to-prevent-candida-albicans-biofilm-growth
#1
Thaisa B Santos, Angela A Vieira, Luciana O Paula, Everton D Santos, Polyana A Radi, Sônia Khouri, Homero S Maciel, Rodrigo S Pessoa, Lucia Vieira
Camphor was incorporated in diamond-like carbon (DLC) films to prevent the Candida albicans yeasts fouling on polyurethane substrates, which is a material commonly used for catheter manufacturing. The camphor:DLC and DLC film for this investigation was produced by plasma enhanced chemical vapor deposition (PECVD), using an apparatus based on the flash evaporation of organic liquid (hexane) containing diluted camphor for camphor:DLC and hexane/methane, mixture for DLC films. The film was deposited at a low temperature of less than 25°C...
February 16, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28212344/green-microwave-assisted-combustion-synthesis-of-zinc-oxide-nanoparticles-with-citrullus-colocynthis-l-schrad-characterization-and-biomedical-applications
#2
Susan Azizi, Rosfarizan Mohamad, Mahnaz Mahdavi Shahri
In this paper, a green microwave-assisted combustion approach to synthesize ZnO-NPs using zinc nitrate and Citrullus colocynthis (L.) Schrad (fruit, seed and pulp) extracts as bio-fuels is reported. The structure, optical, and colloidal properties of the synthesized ZnO-NP samples were studied. Results illustrate that the morphology and particle size of the ZnO samples are different and depend on the bio-fuel. The XRD results revealed that hexagonal wurtzite ZnO-NPs with mean particle size of 27-85 nm were produced by different bio-fuels...
February 16, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
https://www.readbyqxmd.com/read/28212099/high-density-high-radiance-%C3%AE-led-matrix-for-optogenetic-retinal-prostheses-and-planar-neural-stimulation
#3
Ahmed Soltan, Brian McGovern, Emmanuel Drakakis, Mark Neil, Pleun Maaskant, Mahbub Akhter, Jun Su Lee, Patrick Degenaar
Optical neuron stimulation arrays are important for both in-vitro biology and retinal prosthetic biomedical applications. Hence, in this work, we present an 8100 pixel high radiance photonic stimulator. The chip module vertically combines custom made gallium nitride μLEDs with a CMOS application specific integrated circuit. This is designed with active pixels to ensure random access and to allow continuous illumination of all required pixels. The μLEDs have been assembled on the chip using a solder ball flip-chip bonding technique which has allowed for reliable and repeatable manufacture...
February 13, 2017: IEEE Transactions on Biomedical Circuits and Systems
https://www.readbyqxmd.com/read/28211510/broadband-gradient-impedance-matching-using-an-acoustic-metamaterial-for-ultrasonic-transducers
#4
Zheng Li, Dan-Qing Yang, Shi-Lei Liu, Si-Yuan Yu, Ming-Hui Lu, Jie Zhu, Shan-Tao Zhang, Ming-Wei Zhu, Xia-Sheng Guo, Hao-Dong Wu, Xin-Long Wang, Yan-Feng Chen
High-quality broadband ultrasound transducers yield superior imaging performance in biomedical ultrasonography. However, proper design to perfectly bridge the energy between the active piezoelectric material and the target medium over the operating spectrum is still lacking. Here, we demonstrate a new anisotropic cone-structured acoustic metamaterial matching layer that acts as an inhomogeneous material with gradient acoustic impedance along the ultrasound propagation direction. When sandwiched between the piezoelectric material unit and the target medium, the acoustic metamaterial matching layer provides a broadband window to support extraordinary transmission of ultrasound over a wide frequency range...
February 17, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28210442/a-portable-fiber-optic-raman-spectrometer-concept-for-evaluation-of-mineral-content-within-enamel-tissue
#5
Anna Akkus, Shan Yang, Renato Roperto, Hathem Mustafa, Sorin Teich, Ozan Akkus
BACKGROUND: Measurement of tooth enamel mineralization using a clinically viable method is essential since variation of mineralization may be used to monitor caries risk or in assessing the effectiveness of remineralization therapy. Fiber optic Raman systems are becoming more affordable and popular in context of biomedical applications. However, the applicability of fiber optic Raman systems for measurement of mineral content within enamel tissue has not been elucidated significantly in the prior literature...
February 2017: Journal of Clinical and Experimental Dentistry
https://www.readbyqxmd.com/read/28210188/non-contact-photoacoustic-imaging-using-a-commercial-heterodyne-interferometer
#6
Chao Tian, Ting Feng, Cheng Wang, Shengchun Liu, Qian Cheng, David E Oliver, Xueding Wang, Guan Xu
Most current photoacoustic imaging (PAI) systems employ piezoelectric transducers to receive photoacoustic signals, which requires coupling medium to facilitate photoacoustic wave propagation and are not favored in many applications. Here, we report an all-optical non-contact PAI system based on a commercial heterodyne interferometer working at 1550 nm. The interferometer remotely detects ultrasound-induced surface vibration and does not involve any physical contact with the sample. The theoretically predicated and experimentally measured noise equivalent detection limits of the optical sensor are about 4...
December 1, 2016: IEEE Sensors Journal
https://www.readbyqxmd.com/read/28208642/photoluminescent-gold-nanoclusters-in-cancer-cells-cellular-uptake-toxicity-and-generation-of-reactive-oxygen-species
#7
Marija Matulionyte, Dominyka Dapkute, Laima Budenaite, Greta Jarockyte, Ricardas Rotomskis
In recent years, photoluminescent gold nanoclusters have attracted considerable interest in both fundamental biomedical research and practical applications. Due to their ultrasmall size, unique molecule-like optical properties, and facile synthesis gold nanoclusters have been considered very promising photoluminescent agents for biosensing, bioimaging, and targeted therapy. Yet, interaction of such ultra-small nanoclusters with cells and other biological objects remains poorly understood. Therefore, the assessment of the biocompatibility and potential toxicity of gold nanoclusters is of major importance before their clinical application...
February 10, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28198734/new-frontiers-in-intravital-microscopy-of-the-kidney
#8
Andrew M Hall, Claus D Schuh, Dominik Haenni
PURPOSE OF REVIEW: Intravital imaging with multiphoton microscopy enables the detailed study of dynamic cellular processes within functioning organs in living animals, in ways that would not otherwise be possible. It therefore represents a powerful tool in translational kidney research. In this article, we will discuss several new technical developments that have significantly increased the capabilities of kidney imaging. RECENT FINDINGS: Important contemporary advances in biomedical imaging technology include longer wavelength excitation lasers, far-red emitting fluorescent reporters, highly sensitive detectors, fluorescence lifetime measurements, adaptive optics, microendoscopes, high-throughput automated analysis algorithms and tissue clearing techniques...
February 13, 2017: Current Opinion in Nephrology and Hypertension
https://www.readbyqxmd.com/read/28196324/delivery-of-liposomal-quantum-dots-via-monocytes-for-imaging-of-inflamed-tissue
#9
Gil Aizik, Nir Waiskopf, Majd Agbaria, Yael Levi-Kalisman, Uri Banin, Gershon Golomb
Quantum Dots (QDs), semiconductor nanocrystals, are fluorescent nanoparticles of growing interest as an imaging tool of a diseased tissue. However, a major concern is their biocompatibility, cytotoxicity and fluorescence instability in biological milieu, impeding their use in biomedical applications, in general, and for inflammation imaging, in particular. In addition, for an efficient fluorescent signal at the desired tissue, and avoiding systemic biodistribution and possible toxicity, targeting is desired...
February 14, 2017: ACS Nano
https://www.readbyqxmd.com/read/28194944/achieving-high-spatial-resolution-surface-plasmon-resonance-microscopy-with-image-reconstruction
#10
Hui Yu, Xiaonan Shan, Shaopeng Wang, Nongjian Tao
Surface plasmon resonance microscopy (SPRM) is a powerful platform for biomedical imaging and molecular binding kinetics analysis. However, the spatial resolution of SPRM along the plasmon propagation direction (longitudinal) is determined by the decaying length of the plasmonic wave, which can be as large as tens of microns. Different methods have been proposed to improve the spatial resolution but each at the expense of decreased sensitivity or temporal resolution. Here we present a method to achieve high spatial resolution SPRM based on deconvolution of complex field...
February 8, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28186214/monodisperse-phase-transfer-and-surface-bioengineering-of-metal-nanoparticles-via-a-silk-fibroin-protein-corona
#11
Xiao-Wei Huang, Hong Liang, Zhi Li, Jie Zhou, Xian Chen, Shu-Meng Bai, Huang-Hao Yang
Uniform hydrophobic nanoparticles synthesized in nonpolar solvents possess excellent physio-chemical properties, showing great potential in biomedical applications. However, the presence of hydrophobic ligands on their surfaces limits their use under physiological conditions. Inspired by protein coronas present at the nano-bio interface, here we report a facile and universal method for phase transfer and surface bioengineering of hydrophobic nanoparticles using β-sheet-rich silk fibroin, a FDA-approved natural protein...
February 10, 2017: Nanoscale
https://www.readbyqxmd.com/read/28183656/facile-synthesis-of-carbon-dot-and-residual-carbon-nanobeads-implications-for-ion-sensing-medicinal-and-biological-applications
#12
Rohit Ranganathan Gaddam, Sudip Mukherjee, Neelambaram Punugupati, D Vasudevan, Chitta Ranjan Patra, Ramanuj Narayan, Raju Vsn Kothapalli
Synthesis of carbon dots (Cdots) via chemical route involves disintegration of carbon materials into nano-domains, wherein, after extraction of Cdots, the remaining carbon material is discarded. The present work focuses on studying even the leftover carbon residue namely, carbon nanobeads (CNBs) as an equally important material for applications on par with that of carbon dot. It employs oxidative treatment of carbonised gum olibanum resin (GOR) to produce the carbons namely Cdots and CNBs (as the residue). The Cdots (~5-10nm) exhibit blue-green fluorescence with an optical absorption at ~300nm unlike the CNBs (40-50nm) which fail to exhibit fluorescence...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28183629/mechanical-properties-and-in-vivo-study-of-modified-hydroxyapatite-polyetheretherketone-biocomposites
#13
Rui Ma, Qiankuan Li, Lin Wang, Xianghua Zhang, Lin Fang, Zhongkuan Luo, Bai Xue, Lei Ma
Polyether ether ketone (PEEK) has received much attention for its excellent mechanical properties and biocompatibility. Here, the silane coupling agent KH560 [γ-(2,3-epoxypropoxy)propyltrimethoxysilane] is used for graft modification of bioactive HA (hydroxyapatite) particles and for preparing HA/PEEK composites via a hot-press molding method. The prepared HA/PEEK composites were tested for their mechanical properties with SEM (scanning electron microscopy), infrared spectroscopy, and thermo-analysis. The results show that silane coupling KH-560 modifies HA successfully and that the tensile strengths of HA/PEEK and m-HA/PEEK composites indicate an increasing and then a decreasing tendency with increasing HA contents...
April 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/28167811/formation-of-charge-nanopatterned-templates-with-flexible-geometry-via-layer-by-layer-deposition-of-polyelectrolytes-for-directed-self-assembly-of-gold-nanoparticles
#14
Mustafa Sayin, Reiner Dahint
Nanostructure formation via self-assembly processes offers a fast and cost-effective approach to generate surface patterns on large lateral scale. In particular, if the high precision of lithographic techniques is not required, a situation typical of many biotechnological and biomedical applications, it may be considered as the method of choice as it does not require any sophisticated instrumentation. However, in many cases the variety and complexity of the surface structures accessible with a single self-assembly based technique is limited...
February 7, 2017: Nanotechnology
https://www.readbyqxmd.com/read/28164460/development-and-application-of-led-arrays-for-use-in-phototherapy-research
#15
Mohammed A Hadis, Paul R Cooper, Michael R Milward, Patricia C Gorecki, Edward Tarte, James Churm, William M Palin
Lasers/LEDs demonstrate therapeutic effects for a range of biomedical applications. However, a consensus on effective light irradiation parameters and efficient and reliable measurement techniques remain limited. The objective here is to develop, characterise and demonstrate the application of LED arrays in order to progress and improve the effectiveness and accuracy of in vitro photobiomodulation studies. 96-well plate format LED arrays (400-850 nm) were developed and characterised to accurately assess irradiance delivery to cell cultures...
February 6, 2017: Journal of Biophotonics
https://www.readbyqxmd.com/read/28163565/magnetomotive-optical-coherence-elastography-for-magnetic-hyperthermia-dosimetry-based-on-dynamic-tissue-biomechanics
#16
Pin-Chieh Huang, Paritosh Pande, Adeel Ahmad, Marina Marjanovic, Darold R Spillman, Boris Odintsov, Stephen A Boppart
Magnetic nanoparticles (MNPs) have been used in many diagnostic and therapeutic biomedical applications over the past few decades to enhance imaging contrast, steer drugs to targets, and treat tumors via hyperthermia. Optical coherence tomography (OCT) is an optical biomedical imaging modality that relies on the detection of backscattered light to generate high-resolution cross-sectional images of biological tissue. MNPs have been utilized as imaging contrast and perturbative mechanical agents in OCT in techniques called magnetomotive OCT (MM-OCT) and magnetomotive elastography (MM-OCE), respectively...
July 2016: IEEE Journal of Selected Topics in Quantum Electronics
https://www.readbyqxmd.com/read/28152308/yeast-populations-evolve-to-resist-cdse-quantum-dot-toxicity
#17
Alexandra Strtak, Sarmitha Sathiamoorthy, Peter S Tang, Kim M Tsoi, Fayi Song, James B Anderson, Warren C W Chan, Jumi A Shin
Engineered nanomaterials are used globally in biomedical, electronic, and optical devices, and are often discarded into the environment. Cell culture experiments have shown that many inorganic nanoparticles are toxic to eukaryotic cells. Here, we show that populations of eukaryotic cells can evolve to survive chronic exposure to toxic CdSe semiconductor quantum dots (QDs). We grew yeast Saccharomyces cerevisiae for 24 days in liquid medium containing QDs prepared daily at half the minimum inhibitory concentration (MIC50) of the progenitor yeast cells...
February 2, 2017: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/28152274/fe-3-seo42-dual-doped-nano-hydroxyapatite-a-novel-material-for-biomedical-applications
#18
Ammar Z Alshemary, Ahmet Engin Pazarceviren, Aysen Tezcaner, Zafer Evis
Dual ions substituted hydroxyapatite (HA) received attention from scientists and researchers in the biomedical field owing to their excellent biological properties. This paper presents a novel biomaterial, which holds potential for bone tissue applications. Herein, we have successfully incorporated ferric (Fe(3+) )/selenate (SeO42-) ions into the HA structure (Ca10-x-y Fey (PO4 )6-x (SeO4 )x (OH)2-x-y Oy ) (Fe-SeHA) through a microwave refluxing process. The Fe-SeHA materials were characterized by X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, and field emission scanning electron microscopy (FESEM)...
February 2, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28145686/in-situ-characterization-of-protein-adsorption-onto-nanoparticles-by-fluorescence-correlation-spectroscopy
#19
Li Shang, G Ulrich Nienhaus
Nanotechnology holds great promise for applications in many fields including biology and medicine. Unfortunately, the processes occurring at the interface between nanomaterials and living systems are exceedingly complex and not yet well understood, which has significantly hampered the realization of many nanobiotechnology applications. Whenever nanoparticles (NPs) are incorporated by a living organism, a protein adsorption layer, also known as the "protein corona", forms on the NP surface. Accordingly, living organisms interact with protein-coated rather than bare NPs, and their biological responses depend on the nature of the protein corona...
February 1, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28139762/a-portable-luminescent-thermometer-based-on-green-up-conversion-emission-of-er-3-yb-3-co-doped-tellurite-glass
#20
Danilo Manzani, João Flávio da Silveira Petruci, Karina Nigoghossian, Arnaldo Alves Cardoso, Sidney J L Ribeiro
The determination of temperature is essential in many applications in the biomedical, technological, and industrial fields. Optical thermometry appears to be an excellent alternative for conventional electric temperature sensors because it is a non-contact method that offers a fast response, electromagnetic passivity, and high temperature sensitivity. In this paper, we propose an optical thermometer probe comprising an Er(3+)/Yb(3+) co-doped tellurite glass attached to the tip of an optical fibre and optically coupled to a laser source and a portable USB spectrometer...
January 31, 2017: Scientific Reports
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