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Z-F Tang, H-Y Li
OBJECTIVE: To investigate the effect of low intensity ultrasound irradiation combine with fibroblast growth factors (FGF2) on the repair of the knee articular cartilage and to explore its mechanism in rabbit. MATERIALS AND METHODS: The model of the rabbit knee joint injury was established. 40 rabbits were divided into four groups, including control group, model group, FGF2 group and FGF2 + low intensity pulsed ultrasound group (FGF2 + LIPU). The knee joints of rabbits were taken at 4 and 8 weeks, respectively...
April 2018: European Review for Medical and Pharmacological Sciences
Jongin Kim, Boreom Lee
Different modalities such as structural MRI, FDG-PET, and CSF have complementary information, which is likely to be very useful for diagnosis of AD and MCI. Therefore, it is possible to develop a more effective and accurate AD/MCI automatic diagnosis method by integrating complementary information of different modalities. In this paper, we propose multi-modal sparse hierarchical extreme leaning machine (MSH-ELM). We used volume and mean intensity extracted from 93 regions of interest (ROIs) as features of MRI and FDG-PET, respectively, and used p-tau, t-tau, and Aβ42 as CSF features...
May 7, 2018: Human Brain Mapping
Takuma Wakasugi, Ritsuro Shirasaka, Koji Fujita
The Sauve-Kapandji (SK) procedure for distal radioulnar joint osteoarthritis have complications including pain over the proximal ulnar stump, nonunion of the fused distal radioulnar joint, and less frequently, insufficiency fracture of the distal radius. We report a case of insufficiency fracture of the radial diaphysis as a rare complication of the SK procedure.
June 2018: Journal of Hand Surgery Asian-Pacific Volume
Jesse Forbes Doty, Wallace Taylor Harris
The cause and effect between hallux valgus and first ray hypermobility continues to be debated. Understanding the anatomic and radiographic examination of the first metatarsocuneiform (MTC) joint is critical to choosing an appropriate treatment algorithm for the surgical management of hallux valgus deformity. Some studies suggest hypermobility can be corrected without fusing the first MTC joint. Some think hypermobility arises secondarily from malalignment of the soft tissue constraints as the hallux valgus deformity progresses...
June 2018: Foot and Ankle Clinics
Fotios Fousekis, Panagiota Aggeli, Panagiotis Kotsaftis, George Pappas-Gogos
Double pylorus is a rare endoscopic finding that has been reported in 0.001% to 0.4% of upper gastrointestinal endoscopies and can be either congenital or acquired. Acquired double pylorus is usually an uncommon complication of peptic ulcer that erodes and creates a fistula between the duodenal bulb and the prepyloric antrum. We describe a case of a 67-year-old man who experienced mild epigastric pain and dyspepsia over the last 6 months. The patient periodically took nonsteroidal anti-inflammatory drugs (NSAIDs) due to joint pain...
April 2018: Gastroenterology Research
Pravin Salunke, Sushanta K Sahoo
The pathology in congenital atlantoaxial instability is usually in C1-2 joints. Addressing the joints appears to be the most rationale approach. The joints are usually approached posteriorly, manipulated, and fused. Understanding the normal and abnormal anatomy is important. Normally, the third segment of the vertebral artery courses lateral to the C1-2 joint. However, in about 20% of the cases with complex congenital craniovertberal junction anomalies the artery crosses the joint posteriorly. The artery in such cases may be injured while joint manipulation and instrumentation with disastrous consequences...
April 26, 2018: Operative Neurosurgery (Hagerstown, Md.)
Christopher John Moody, Steven Wales, Elena Merisor, Holly Adcock, Christopher Pearce, Ian Strutt, William Lewis, Daniel Hamza
A series of highly substituted tetrahydrofurans (THFs), decorated with modifiable 2-aryl, 3-carboxy and 4-amino substituents, has been prepared for biological evaluation within the European Lead Factory. Diastereoselective reductive amination of pre-functionalised 4-oxofurans, readily prepared from cinnamate esters via oxa-Michael/Dieckmann annulation, provided the requisite THF cores on gram scale with three contiguous stereocentres, including full substitution at C-3. In a second series, a pyrrolidine ring was fused to the same oxofuran scaffold via an intramolecular reductive amination, inverting the configuration at C-4 relative to the other ring substituents...
April 14, 2018: Chemistry: a European Journal
Timo Viljakka, Kaj Tallroth, Martti Vastamäki
PURPOSE: Titanium lunate arthroplasty (TLA) for Kienböck disease was introduced in 1984 to address the silicone-wear particle problem common to silicone lunate implants. We sought to study the outcome of TLA. METHODS: We identified 11 patients from our hospital database who had undergone TLA between 2001 and 2010. We evaluated pain, range of motion (ROM), function, and radiological outcome at a mean 11 years after surgery. We compared preoperative ROM and radiological findings with final follow-up in the ipsilateral wrist and also made comparisons with the contralateral wrists...
April 9, 2018: Journal of Hand Surgery
Yue Zhou, Ju-Peng Li, Wen-Chao Lv, Ruo-Han Ma, Gang Li
OBJECTIVES: A method was introduced for three-dimensional (3D) cone-beam computed tomography (CBCT) images registration of temporomandibular joint (TMJ). This study aimed to provide quantitative and qualitative analysis of TMJ bone changes in two-dimensional (2D) and 3D and to provide the technique for computer aided diagnosis of temporomandibular joint disorders (TMD) in the future. METHODS: Ten TMJ samples of six patients were obtained from Peking University Hospital of Stomatology...
March 29, 2018: Dento Maxillo Facial Radiology
Christian Lyons, Michael Ross, Ryan Elliott, Michael Tall
The purpose of this report is to describe the evaluation and treatment of a patient with neck pain and ankylosing spondylitis who had underlying atlantoaxial instability. The patient was a 31-yr-old man diagnosed with ankylosing spondylitis 1 yr prior who was referred to a physical therapist for the treatment of chronic, worsening low back and hip pain. He also had secondary complaints of neck, upper back, and shoulder pain. The patient worked as a military pilot. As part of the patient's physical examination, a Sharp-Purser test was performed, which was positive for excessive motion...
March 26, 2018: Military Medicine
Schneider K Rancy, Eugene T Ek, Sophia Paul, Robert N Hotchkiss, Scott W Wolfe
Purpose  This study aims to compare the outcomes and complications of our technique for nonspanning total wrist arthrodesis using a locking plate with the standard carpometacarpal spanning technique. Methods  A retrospective review of charts was performed to identify patients who underwent total wrist arthrodesis by the senior author (S.W.W.). We compared the outcomes of 15 cases of nonspanning wrist fusion with a 2.4/2.7 mm locking T plate to 11 cases of spanning wrist fusion with a 2.7/3.5 mm locking compression plate...
April 2018: Journal of Wrist Surgery
Jaeil Kim, Geng Chen, Weili Lin, Pew-Thian Yap, Dinggang Shen
Constructing longitudinal diffusion-weighted atlases of infant brains poses additional challenges due to the small brain size and the dynamic changes in the early developing brains. In this paper, we introduce a novel framework for constructing longitudinally-consistent diffusion-weighted infant atlases with improved preservation of structural details and diffusion characteristics. In particular, instead of smoothing diffusion signals by simple averaging, our approach fuses the diffusion-weighted images in a patch-wise manner using sparse representation with a graph constraint that encourages spatiotemporal consistency...
September 2017: Medical Image Computing and Computer-assisted Intervention: MICCAI ..
Keisuke Sugahara, Yoshiharu Katsumi, Masahide Koyachi, Yu Koyama, Satoru Matsunaga, Kento Odaka, Shinichi Abe, Masayuki Takano, Akira Katakura
Background: Along with the advances in technology of three-dimensional (3D) printer, it became a possible to make more precise patient-specific 3D model in the various fields including oral and maxillofacial surgery. When creating 3D models of the mandible and maxilla, it is easier to make a single unit with a fused temporomandibular joint, though this results in poor operability of the model. However, while models created with a separate mandible and maxilla have operability, it can be difficult to fully restore the position of the condylar after simulation...
December 2018: Maxillofacial Plastic and Reconstructive Surgery
Xingbin Liu, Wenbo Mei, Huiqian Du
In this paper, a detail-enhanced multimodality medical image fusion algorithm is proposed by using proposed multi-scale joint decomposition framework (MJDF) and shearing filter (SF). The MJDF constructed with gradient minimization smoothing filter (GMSF) and Gaussian low-pass filter (GLF) is used to decompose source images into low-pass layers, edge layers, and detail layers at multiple scales. In order to highlight the detail information in the fused image, the edge layer and the detail layer in each scale are weighted combined into a detail-enhanced layer...
February 13, 2018: Medical & Biological Engineering & Computing
Hai-Bo Zhou, Chao Zhang, Li-Chuang Wu, Cai-Long Liu
OBJECTIVE: To explore plantar pressure measurement system in treating the first ray hypermobility. METHODS: From June 2013 to January 2014, 16 female patients (20 feet) with hallux valgus with unstable of the first sequence were treated by first tarsometatarsal joint fusion, aged from 42 to 52 years old with an average of(46.5±2.9) years old, the course of disease was from 3 to 5 years. Twenty healthy female(20 feet) were chosen as control group, and single side were only choose, aged from 41 to 55 years old with an average of(46...
June 25, 2017: Zhongguo Gu Shang, China Journal of Orthopaedics and Traumatology
Pei Dong, Li Wang, Weili Lin, Dinggang Shen, Guorong Wu
The first year of life is the most dynamic and perhaps the most critical phase of postnatal brain development. The ability to accurately measure structure changes is critical in early brain development study, which highly relies on the performances of image segmentation and registration techniques. However, either infant image segmentation or registration, if deployed independently, encounters much more challenges than segmentation/registration of adult brains due to dynamic appearance change with rapid brain development...
March 15, 2017: Neurocomputing
H Willmott, Z Al-Wattar, C Halewood, M Dunning, A Amis
BACKGROUND: The first metatarsophalangeal joint may be fused in order to treat arthritis or instability. The use of shape-memory staples for fixation is well recognised, but little work has been done into the optimal configuration of staples. METHODS: The structural behaviour of first metatarsophalangeal joint (MTPJ) arthrodeses using shape-memory staples or crossed screws was studied using cadaveric porcine joints. Five fixation configurations were tested: single vertical or horizontal staple, paired staples in dorsal-medial configuration (0-90° to the sagittal plane), paired staples in oblique orthogonal configuration (45-135°); or two crossed screws...
March 18, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Federico Canavese, Alain Dimeglio, François Bonnel
BACKGROUND: Several anatomical studies have shown that the articular facets of the calcaneus can present with different anatomy. This study assessed the 3D anatomy of lateral calcaneal lengthening (LCL) osteotomy in relation to the anterior and middle facet of the calcaneus in a group of skeletally immature patients treated for symptomatic flatfoot deformity. METHODS: During the study period, 14 consecutive patients (10 males, 4 females) presenting symptomatic flatfoot (20 feet) with different aetiologies underwent LCL osteotomy and CT scan with 3D reconstruction of the operated feet...
June 3, 2017: Foot and Ankle Surgery: Official Journal of the European Society of Foot and Ankle Surgeons
Augusto Atilio Covaro, Nodoka Manabe, Lukas Bobinski, Claes Olerud, Yohan Robinson
Study Design: This was a retrospective analysis of prospectively collected data. Objective: The effect of C0-C1-C2 cervical ankylosis in patients with ankylosing spondylitis (AS) is not documented. The objective of this study is to describe the radiological characteristics of the occipitocervical junction in patients with AS operated for a cervical fracture and to correlate them with their clinical evolution. Materials and Methods: Analysis of patients with ankylosing spondylitis (AS) treated in a single institution of a cervical vertebral fracture between 2007 and 2014 who were prospectively followed through the SWESPINE registry...
October 2017: Journal of Craniovertebral Junction and Spine
Samer S Ghostine, Paul E Kaloostian, Christ Ordookhanian, Sean Kaloostian, Parham Zarrini, Terrence Kim, Stephen Scibelli, Scott J Clark-Schoeb, Srinath Samudrala, Carl Lauryssen, Amandip S Gill, Patrick J Johnson
The surgical repair of atlantoaxial instabilities (AAI) presents complex and unique challenges, originating from abnormalities and/or trauma within the junction regions of the C1-C2 atlas-axis, to surgeons. When this region is destabilized, surgical fusion becomes of key importance in order to prevent spinal cord injury. Several techniques can be utilized to provide for the adequate fusion of the atlantoaxial construct. Nevertheless, many individuals have less than ideal rates of fusion, below 35%-40%, which also involves the C2 nerve root being sacrificed...
November 29, 2017: Curēus
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