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https://www.readbyqxmd.com/read/27921292/cranial-joint-histology-in-the-mallard-duck-anas-platyrhynchos-new-insights-on-avian-cranial-kinesis
#1
Alida M Bailleul, Lawrence M Witmer, Casey M Holliday
The evolution of avian cranial kinesis is a phenomenon in part responsible for the remarkable diversity of avian feeding adaptations observable today. Although osteological, developmental and behavioral features of the feeding system are frequently studied, comparatively little is known about cranial joint skeletal tissue composition and morphology from a microscopic perspective. These data are key to understanding the developmental, biomechanical and evolutionary underpinnings of kinesis. Therefore, here we investigated joint microstructure in juvenile and adult mallard ducks (Anas platyrhynchos; Anseriformes)...
December 6, 2016: Journal of Anatomy
https://www.readbyqxmd.com/read/27919672/a-study-of-pre-operative-presence-of-micro-organisms-in-affected-knee-joints-of-rheumatoid-arthritis-patients-who-need-total-knee-arthroplasty
#2
Jiang-Ming Luo, Lin Guo, Hao Chen, Peng-Fei Yang, Ran Xiong, Yang Peng, Liu Yang
BACKGROUND: To evaluate, by way of intraoperative tissue culture and pathological study, the pre-operative presence of micro-organisms in knee joints of patients with rheumatoid arthritis (RA) who need total knee arthroplasty (TKA). METHODS: From November 2012 to January 2014, 47 patients with RA (53 knees) who needed TKA were included in this study. Patients received routine pre-operative examination and joint fluid routine and culture. Each RA patient was match-paired with one osteoarthritis (OA) patient...
December 2, 2016: Knee
https://www.readbyqxmd.com/read/27913783/three-dimensional-printed-prosthesis-demonstrates-functional-improvement-in-a-patient-with-an-amputated-thumb-a-technical-note
#3
Keun Ho Lee, Sung Jae Kim, Yong Ho Cha, Jae Lim Kim, Dong Kyu Kim, Sang Jun Kim
BACKGROUND AND AIM: Three-dimensional printer is widely used in industry, biology, and medical fields. We report a finger prosthesis produced by a three-dimensional scanner and printer for a 67-year-old man with a right thumb amputation above the metacarpophalangeal joint. TECHNIQUE: His right amputated and left intact hands were scanned with a three-dimensional scanner, and the left-hand image was rotated to the right side to design the right thumb prosthesis. The designed prosthesis was printed with a three-dimensional printer using the fused filament fabrication output system...
December 1, 2016: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/27913362/learning-to-predict-eye-fixations-via-multiresolution-convolutional-neural-networks
#4
Nian Liu, Junwei Han, Tianming Liu, Xuelong Li
Eye movements in the case of freely viewing natural scenes are believed to be guided by local contrast, global contrast, and top-down visual factors. Although a lot of previous works have explored these three saliency cues for several years, there still exists much room for improvement on how to model them and integrate them effectively. This paper proposes a novel computation model to predict eye fixations, which adopts a multiresolution convolutional neural network (Mr-CNN) to infer these three types of saliency cues from raw image data simultaneously...
November 29, 2016: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/27891496/interpositional-gap-arthroplasty-by-versatile-pedicled-temporalis-myofascial-flap-in-the-management-of-temporomandibular-joint-ankylosis-a-case-series-study
#5
Vikas Aneja, Rushik Raval, Anupam Bansal, Vinod Kumawat, Jasleen Kaur, Ahemer Arif Shaikh
Temporomandibular Joint (TMJ) ankylosis is a situation in which the mandibular condyle is fused to the glenoid fossa by bone or fibrous tissue. The management of TMJ ankylosis has a complicated chore and it is challenging for the maxillofacial surgeon because of technical hitches and high rate of re-ankylosis. Interpositional gap arthroplasty is one of the modalities for its management. A range of inter-positional materials have been used to avert recurrence after gap arthroplasty in TMJ ankylosis. The aim of this series was to evaluate the effectiveness of the temporomyofacial flap in the treatment of TMJ ankylosis as an interpositional gap arthroplasty...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27887621/pediatric-emergency-department-visits-and-ambient-air-pollution-in-the-u-s-state-of-georgia-a-case-crossover-study
#6
Qingyang Xiao, Yang Liu, James A Mulholland, Armistead G Russell, Lyndsey A Darrow, Paige E Tolbert, Matthew J Strickland
BACKGROUND: Estimating the health effects of ambient air pollutant mixtures is necessary to understand the risk of real-life air pollution exposures. METHODS: Pediatric Emergency Department (ED) visit records for asthma or wheeze (n = 148,256), bronchitis (n = 84,597), pneumonia (n = 90,063), otitis media (n = 422,268) and upper respiratory tract infection (URI) (n = 744,942) were obtained from Georgia hospitals during 2002-2008. Spatially-contiguous daily concentrations of 11 ambient air pollutants were estimated from CMAQ model simulations that were fused with ground-based measurements...
November 25, 2016: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/27867700/mental-stress-assessment-using-simultaneous-measurement-of-eeg-and-fnirs
#7
Fares Al-Shargie, Masashi Kiguchi, Nasreen Badruddin, Sarat C Dass, Ahmad Fadzil Mohammad Hani, Tong Boon Tang
Previous studies reported mental stress as one of the major contributing factors leading to various diseases such as heart attack, depression and stroke. An accurate stress assessment method may thus be of importance to clinical intervention and disease prevention. We propose a joint independent component analysis (jICA) based approach to fuse simultaneous measurement of electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) on the prefrontal cortex (PFC) as a means of stress assessment...
October 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27857857/predictive-parameters-for-the-antecedent-development-of-hip-pathology-associated-with-long-segment-fusions-to-the-pelvis-for-the-treatment-of-adult-spinal-deformity
#8
Merritt D Kinon, Rani Nasser, Jonathan P Nakhla, Owoicho Adogwa, Jessica R Moreno, Michael Harowicz, Terence Verla, Reza Yassari, Carlos A Bagley
BACKGROUND: The surgical treatment of adult scoliosis frequently involves long segment fusions across the lumbosacral joints that redistribute tremendous amounts of force to the remaining mobile spinal segments as well as to the pelvis and hip joints. Whether or not these forces increase the risk of femoral bone pathology remains unknown. The aim of this study is to determine the correlation between long segment spinal fusions to the pelvis and the antecedent development of degenerative hip pathologies as well as what predictive patient characteristics, if any, correlate with their development...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27849523/videostory-embeddings-recognize-events-when-examples-are-scarce
#9
Amirhossein Habibian, Thomas Mensink, Cees G M Snoek
This paper aims for event recognition when video examples are scarce or even completely absent. The key in such a challenging setting is a semantic video representation. Rather than building the representation from individual attribute detectors and their annotations, we propose to learn the entire representation from freely available web videos and their descriptions using an embedding between video features and term vectors. In our proposed embedding, which we call Video2vec, the correlations between the words are utilized to learn a more effective representation by optimizing a joint objective balancing descriptiveness and predictability...
November 10, 2016: IEEE Transactions on Pattern Analysis and Machine Intelligence
https://www.readbyqxmd.com/read/27821660/limb-salvage-after-failed-initial-operative-management-of-bimalleolar-ankle-fractures-in-diabetic-neuropathy
#10
Nicholas J Vaudreuil, Mitchell S Fourman, Dane K Wukich
BACKGROUND: Ankle fractures in patients with diabetes mellitus (DM) can be difficult to manage, especially in the presence of peripheral neuropathy. In patients who fail initial operative management, attempts at limb salvage can be challenging, and no clear treatment algorithm exists. This study examined outcomes of different procedures performed for limb salvage in this population. METHODS: This study retrospectively reviewed 17 patients with DM complicated by peripheral neuropathy who sustained a bimalleolar ankle fracture and failed initial operative management...
November 7, 2016: Foot & Ankle International
https://www.readbyqxmd.com/read/27813020/new-insight-in-the-architecture-of-the-quadriceps-tendon
#11
Karl Grob, Mirjana Manestar, Luis Filgueira, Timothy Ackland, Helen Gilbey, Markus S Kuster
BACKGROUND: Published data regarding the structure of the quadriceps tendon are diverse. Dissection of the quadriceps muscle group revealed that beside the rectus femoris, vastus lateralis, vastus intermedius and vastus medialis a fifth muscle component- named the tensor vastus intermedius consistently fused into quadriceps tendon. It can be hypothesized that all these elements of the extensor apparatus of the knee joint must also be represented in the quadriceps tendon. This study investigated the multi-layered quadriceps tendon with special emphasis on all components of the quadriceps muscle group including the newly discovered tensor vastus intermedius...
December 2016: Journal of Experimental Orthopaedics
https://www.readbyqxmd.com/read/27810834/cancer-subtype-discovery-based-on-integrative-model-of-multigenomic-data
#12
Shu-Guang Ge, Junfeng Xia, Wen Sha, Chun-Hou Zheng
One major goal of large-scale cancer omics study is to understand molecular mechanisms of cancer and find new biomedical targets. To deal with the high-dimensional multidimensional cancer omics data (DNA methylation, mRNA expression, etc.), which can be used to discover new insight on identifying cancer subtypes, clustering methods are usually used to find an effective low-dimensional subspace of the original data and then cluster cancer samples in the reduced subspace. However, due to data-type diversity and big data volume, few methods can integrate these data and map them into an effective low-dimensional subspace...
October 26, 2016: IEEE/ACM Transactions on Computational Biology and Bioinformatics
https://www.readbyqxmd.com/read/27790414/subtalar-joint-instability-and-calcaneal-spurs-associated-with-the-configuration-of-the-articular-facets-of-adult-human-calcaneum-in-indian-population
#13
Shilpi Agarwal, Shilpi Garg, Neelam Vasudeva
INTRODUCTION: Morphological variations of articular facets of calcaneum may predispose people to joint instability, ligamentous laxity and development of arthritic changes in the subtalar joint. Knowledge of such variations is essential for treatment and diagnostic procedures in orthopaedic surgeries. AIM: The aim of this study was to determine patterns of articular facets of calcanei and to establish its correlation with calcaneal spurs. MATERIALS AND METHODS: The study was conducted on 580 adult calcanei of Indian origin at Maulana Azad Medical College and pattern of articular facets were observed and classified according to five patterns described in literature...
September 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27781989/proximodistal-interphalangeal-arthrodesis-of-the-little-finger-a-series-of-7-cases
#14
S Honecker, J J Hidalgo Diaz, K Naito, E Pire, G Prunières, S Facca, P Liverneaux
As an alternative to amputation of the little finger, we report here seven cases of shortening arthrodesis carried out by resecting the middle phalanx and proximodistal interphalangeal (PDIP) arthrodesis. Our cohort consisted of 6 males and 1 female (58years average age), with a stiff little finger secondary to Dupuytren's disease or trauma. All fingers were approached dorsally; after resection of the middle phalanx and decortication of the subchondral bone, fusion of the remaining phalanges was performed using an intramedullary self-breaking screw-pin...
September 2016: Hand Surgery and Rehabilitation
https://www.readbyqxmd.com/read/27774453/dual-modality-imaging-of-the-human-finger-joint-systems-by-using-combined-multispectral-photoacoustic-computed-tomography-and-ultrasound-computed-tomography
#15
Yubin Liu, Yating Wang, Zhen Yuan
We developed a homemade dual-modality imaging system that combines multispectral photoacoustic computed tomography and ultrasound computed tomography for reconstructing the structural and functional information of human finger joint systems. The fused multispectral photoacoustic-ultrasound computed tomography (MPAUCT) system was examined by the phantom and in vivo experimental tests. The imaging results indicate that the hard tissues such as the bones and the soft tissues including the blood vessels, the tendon, the skins, and the subcutaneous tissues in the finger joints systems can be effectively recovered by using our multimodality MPAUCT system...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27694625/challenges-of-crispr-cas9-applications-for-long-non-coding-rna-genes
#16
Ashish Goyal, Ksenia Myacheva, Matthias Groß, Marcel Klingenberg, Berta Duran Arqué, Sven Diederichs
The CRISPR/Cas9 system provides a revolutionary genome editing tool for all areas of molecular biology. In long non-coding RNA (lncRNA) research, the Cas9 nuclease can delete lncRNA genes or introduce RNA-destabilizing elements into their locus. The nuclease-deficient dCas9 mutant retains its RNA-dependent DNA-binding activity and can modulate gene expression when fused to transcriptional repressor or activator domains. Here, we systematically analyze whether CRISPR approaches are suitable to target lncRNAs...
September 30, 2016: Nucleic Acids Research
https://www.readbyqxmd.com/read/27630481/chronic-neglected-irreducible-atlantoaxial-rotatory-subluxation-in-adolescence
#17
Pravin Padalkar
UNLABELLED: Atlantoaxial rotatory fixation (AARF) is a rare condition and delayed diagnosis. We report a case of chronic neglected atlantoaxial rotatory subluxation in adolescence child that was treated by serial skull traction followed by posterior fusing by method pioneered by Goel et al. A 15-year-old male presented with signs of high cervical myelopathy 2 years after trauma to neck childhood. There was upper cervical kyphosis, direct tenderness over C2 spinous process, atrophy of both hand muscles with weakness in grip strength...
July 2016: Journal of Craniovertebral Junction and Spine
https://www.readbyqxmd.com/read/27626763/biomechanical-evaluation-of-novel-ultrasound-activated-bioresorbable-pins-for-the-treatment-of-osteochondral-fractures-compared-to-established-methods
#18
Benjamin Kienast, Hellal Mohsen, Robert Wendlandt, Nils Reimers, Arndt P Schulz, Hinrich Heuer, Justus Gille, Hanjo Neumann
BACKGROUND: Osteochondral injuries often lead to osteoarthritis of the affected joint. All established systems for refixation of osteochondral defects show certain disadvantages. To address the problem of reduced stability in resorbable implants, ultrasound-activated pins were developed. By ultrasound-activated melting of the tip of these implants, a more secure anchoring is assumed. MATERIALS AND METHODS: The aim of the study was to investigate if ultrasound-activated pins can provide secure fixation of osteochondral fragments compared to screws and conventional resorbable pins...
September 2, 2016: Biomedizinische Technik. Biomedical Engineering
https://www.readbyqxmd.com/read/27606933/3d-printing-of-novel-osteochondral-scaffolds-with-graded-microstructure
#19
Margaret A Nowicki, Nathan J Castro, Michael W Plesniak, Lijie Grace Zhang
Osteochondral tissue has a complex graded structure where biological, physiological, and mechanical properties vary significantly over the full thickness spanning from the subchondral bone region beneath the joint surface to the hyaline cartilage region at the joint surface. This presents a significant challenge for tissue-engineered structures addressing osteochondral defects. Fused deposition modeling (FDM) 3D bioprinters present a unique solution to this problem. The objective of this study is to use FDM-based 3D bioprinting and nanocrystalline hydroxyapatite for improved bone marrow human mesenchymal stem cell (hMSC) adhesion, growth, and osteochondral differentiation...
October 14, 2016: Nanotechnology
https://www.readbyqxmd.com/read/27598156/multi-sensor-consensus-estimation-of-state-sensor-biases-and-unknown-input
#20
Jie Zhou, Yan Liang, Feng Yang, Linfeng Xu, Quan Pan
This paper addresses the problem of the joint estimation of system state and generalized sensor bias (GSB) under a common unknown input (UI) in the case of bias evolution in a heterogeneous sensor network. First, the equivalent UI-free GSB dynamic model is derived and the local optimal estimates of system state and sensor bias are obtained in each sensor node; Second, based on the state and bias estimates obtained by each node from its neighbors, the UI is estimated via the least-squares method, and then the state estimates are fused via consensus processing; Finally, the multi-sensor bias estimates are further refined based on the consensus estimate of the UI...
2016: Sensors
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