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https://www.readbyqxmd.com/read/28097823/excess-retinoic-acid-induces-fusion-of-centra-by-degenerating-intervertebral-ligament-cells-in-japanese-flounder-paralichthys-olivaceus
#1
Xiaoming Wu, Qiran Chen, Youhei Washio, Hayato Yokoi, Tohru Suzuki
In marine aquaculture fish, excessive supplement of vitamin A (VA) to zooplanktons for larval culture and experimental exposure of larvae to retinoic acid (RA: active form of VA) have been known to cause vertebral deformity. However, the tissues in the developing vertebral column that are affected by RA and the progression of vertebral deformity remain undetermined. To examine these questions, we histologically traced the progress of vertebral deformity induced by RA in Japanese flounder (Paralichthys olivaceus)...
January 18, 2017: Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution
https://www.readbyqxmd.com/read/28091426/mri-based-detailed-evaluation-of-the-anatomy-of-the-human-coccyx-among-turkish-adults
#2
H Tetiker, M I Koşar, N Çullu, U Canbek, I Otağ, Y Taştemur
AIM: The human coccyx varies considerably in shape and size. The objective of this study was to investigate the morphology and morphometry of the coccyx on pelvic magnetic resonance imaging in asymptomatic individuals among Turkish adults. MATERIALS AND METHODS: This study was conducted retrospectively on the pelvic magnetic resonance images of 456 adult patients without a history of trauma in the coccyx region. The coccygeal vertebrae count, number of bone segments, and intercoccygeal and sacrococcygeal joint fusions were determined from the sagittal plane images...
February 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/28071847/hindfoot-fusion-in-haemophilic-arthropathy-6-year-mean-follow-up-of-41-procedures-performed-in-28-adult-patients
#3
M Brkljac, S Shah, C Hay, E C Rodriguez-Merchan
INTRODUCTION: Haemophilic arthropathy of the ankle is rare disorder caused by recurrent haemarthorses beginning in early adulthood. AIM: Our aim was to evaluate the fusion rate of various techniques of hindfoot fusion using internal fixation for the treatment of haemophilic arthropathy of the hindfoot. METHODS: We have evaluated the fusion rate of various techniques of hindfoot (tibiotalar and subtalar joints) fusion for the treatment of haemophilic arthropathy of the hindfoot...
March 2016: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/28069162/a-constrained-extended-kalman-filter-for-the-optimal-estimate-of-kinematics-and-kinetics-of-a-sagittal-symmetric-exercise
#4
V Bonnet, R Dumas, A Cappozzo, V Joukov, G Daune, D Kulić, P Fraisse, S Andary, G Venture
This paper presents a method for real-time estimation of the kinematics and kinetics of a human body performing a sagittal symmetric motor task, which would minimize the impact of the stereophotogrammetric soft tissue artefacts (STA). The method is based on a bi-dimensional mechanical model of the locomotor apparatus the state variables of which (joint angles, velocities and accelerations, and the segments lengths and inertial parameters) are estimated by a constrained extended Kalman filter (CEKF) that fuses input information made of both stereophotogrammetric and dynamometric measurement data...
December 29, 2016: Journal of Biomechanics
https://www.readbyqxmd.com/read/28065978/spontaneous-bilateral-quadriceps-rupture-in-a-patient-with-ankylosing-spondylitis-a-case-report
#5
Azib Shahid, Hafiz Shahid Mushtaq, Syed Muhammad Azfar
Ankylosing spondylitis is a prototype rheumatoid factor-negative spondyloarthropathy that causes the vertebrae to fuse making the spine less flexible, resulting in a hunched-forward posture. A 47-year-old male who was a known case of ankylosing spondylitis presented with left quadriceps rupture after raising his right foot to lightly hit a football. He was fitted with a knee immobilizer as an emergency measure. The extent of the rupture was not yet established when patient requested leave to go home. The right quadriceps was ruptured as well when he took his immobilizer off to go the bathroom...
January 2017: JPMA. the Journal of the Pakistan Medical Association
https://www.readbyqxmd.com/read/28042117/spinopelvic-mobility-and-acetabular-component-position-for-total-hip-arthroplasty
#6
M Stefl, W Lundergan, N Heckmann, B McKnight, H Ike, R Murgai, L D Dorr
AIMS: Posterior tilt of the pelvis with sitting provides biological acetabular opening. Our goal was to study the post-operative interaction of skeletal mobility and sagittal acetabular component position. MATERIALS AND METHODS: This was a radiographic study of 160 hips (151 patients) who prospectively had lateral spinopelvic hip radiographs for skeletal and implant measurements. Intra-operative acetabular component position was determined according to the pre-operative spinal mobility...
January 2017: Bone & Joint Journal
https://www.readbyqxmd.com/read/28033151/spinal-realignment-for-adult-deformity-three-column-osteotomies-alter-total-hip-acetabular-component-positioning
#7
Jeffrey J Barry, Altug Yucekul, Alexander A Theologis, Erik N Hansen, Christopher Ames, Vedat Deviren
INTRODUCTION: A goal of adult spinal deformity surgery is correction of sagittal imbalance by increasing lumbar lordosis (LL), allowing a previously retroverted pelvis to normalize as evidenced by decreases in pelvic tilt (PT). Realignment of pelvic orientation may alter the position of preexisting total hip arthroplasties (THAs). METHODS: Twenty-seven patients with unilateral THA who underwent thoracolumbar fusions for adult spinal deformity from the pelvis to L1 or above were retrospectively reviewed (levels fused, 10...
February 2017: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/27989703/usefulness-of-mri-cbct-image-registration-in-the-evaluation-of-temporomandibular-joint-internal-derangement-by-novice-examiners
#8
Mohammed A Q Al-Saleh, Noura Alsufyani, Hollis Lai, Manuel Lagravere, Jacob L Jaremko, Paul W Major
OBJECTIVE: To assess whether novice examiners can more reliably determine temporomandibular joint (TMJ) disk derangements with the use of fused images of magnetic resonance imaging and cone beam computed tomography (MRI-CBCT) compared with MRI images alone. STUDY DESIGN: Thirty dental students with minimal exposure to TMJ imaging received a 30-minute calibration session in which TMJ diagnostic imaging and the normal anatomy of the TMJ internal derangement were explained...
November 2, 2016: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/27988873/coagulation-factor-ix-recombinant-albumin-fusion-protein-albutrepenonacog-alfa-idelvion-%C3%A2-a-review-of-its-use-in-haemophilia-b
#9
Katherine A Lyseng-Williamson
Albutrepenonacog alfa (Idelvion(®)), a fusion protein that genetically fuses recombinant factor IX (rFIX) with recombinant human albumin (rAlbumin), is indicated in the treatment of haemophilia B. This narrative review discusses the pharmacological properties and clinical data related to the use of this novel fusion protein, hereafter referred to as rIX-FP. The fusion of rFIX to rAlbumin prolongs the elimination half-life of rIX-FP in the circulation, allowing routine prophylaxis to be administered once every 7-14 days...
December 17, 2016: Drugs
https://www.readbyqxmd.com/read/27965071/a-betulinic-acid-derivative-sh479-inhibits-collagen-induced-arthritis-by-modulating-t-cell-differentiation-and-cytokine-balance
#10
Shijie Chen, Yang Bai, Zhen Li, Kunhang Jia, Yunyun Jin, Bei He, Wen-Wei Qiu, Changsheng Du, Stefan Siwko, Huaqing Chen, Mingyao Liu, Jian Luo
The ideal therapeutic drug for rheumatoid arthritis (RA) should not only inhibit inflammation, but also prevent articular joint damage and particularly inhibit osteoclastogenesis. Betulinic acid (BA) is a natural pentacyclic triterpene that has displayed moderate anti-inflammatory and anti-osteoclastogenesis activities in various experimental systems, suggesting that BA or its derivatives could have an inhibitory effect on RA. In this study, we screened BA derivatives and found a heterocyclic ring-fused BA derivative, SH479, which had greater inhibitory effect than BA on Th17 differentiation...
December 11, 2016: Biochemical Pharmacology
https://www.readbyqxmd.com/read/27935925/clinical-evaluation-of-fused-ankylosed-hip-with-severe-flexion-deformity-after-conversion-to-total-hip-arthroplasty
#11
S K Suwal, P Songming, L Gang, H Kui
INTRODUCTION: Fused or Ankylosed hip is late complication of chronic inflammatory disorder with progressive changes in and around articular as well as periarticular structures with alteration in bio-force line of body which later lead to severe flexion deformity of joint. This not only results decreased movements of hip, it's also increase pain around the hip, back and contralateral hip. METHODS: Retrospectively, all patients aged 18 years or older undergoing THA between June 2006 to June 2012 were reviewed with selection criteria...
April 2016: JNMA; Journal of the Nepal Medical Association
https://www.readbyqxmd.com/read/27921292/cranial-joint-histology-in-the-mallard-duck-anas-platyrhynchos-new-insights-on-avian-cranial-kinesis
#12
Alida M Bailleul, Lawrence M Witmer, Casey M Holliday
The evolution of avian cranial kinesis is a phenomenon in part responsible for the remarkable diversity of avian feeding adaptations observable today. Although osteological, developmental and behavioral features of the feeding system are frequently studied, comparatively little is known about cranial joint skeletal tissue composition and morphology from a microscopic perspective. These data are key to understanding the developmental, biomechanical and evolutionary underpinnings of kinesis. Therefore, here we investigated joint microstructure in juvenile and adult mallard ducks (Anas platyrhynchos; Anseriformes)...
December 6, 2016: Journal of Anatomy
https://www.readbyqxmd.com/read/27919672/a-study-of-pre-operative-presence-of-micro-organisms-in-affected-knee-joints-of-rheumatoid-arthritis-patients-who-need-total-knee-arthroplasty
#13
Jiang-Ming Luo, Lin Guo, Hao Chen, Peng-Fei Yang, Ran Xiong, Yang Peng, Liu Yang
BACKGROUND: To evaluate, by way of intraoperative tissue culture and pathological study, the pre-operative presence of micro-organisms in knee joints of patients with rheumatoid arthritis (RA) who need total knee arthroplasty (TKA). METHODS: From November 2012 to January 2014, 47 patients with RA (53 knees) who needed TKA were included in this study. Patients received routine pre-operative examination and joint fluid routine and culture. Each RA patient was match-paired with one osteoarthritis (OA) patient...
December 2, 2016: Knee
https://www.readbyqxmd.com/read/27913783/three-dimensional-printed-prosthesis-demonstrates-functional-improvement-in-a-patient-with-an-amputated-thumb-a-technical-note
#14
Keun Ho Lee, Sung Jae Kim, Yong Ho Cha, Jae Lim Kim, Dong Kyu Kim, Sang Jun Kim
BACKGROUND AND AIM: Three-dimensional printer is widely used in industry, biology, and medical fields. We report a finger prosthesis produced by a three-dimensional scanner and printer for a 67-year-old man with a right thumb amputation above the metacarpophalangeal joint. TECHNIQUE: His right amputated and left intact hands were scanned with a three-dimensional scanner, and the left-hand image was rotated to the right side to design the right thumb prosthesis. The designed prosthesis was printed with a three-dimensional printer using the fused filament fabrication output system...
December 1, 2016: Prosthetics and Orthotics International
https://www.readbyqxmd.com/read/27913362/learning-to-predict-eye-fixations-via-multiresolution-convolutional-neural-networks
#15
Nian Liu, Junwei Han, Tianming Liu, Xuelong Li
Eye movements in the case of freely viewing natural scenes are believed to be guided by local contrast, global contrast, and top-down visual factors. Although a lot of previous works have explored these three saliency cues for several years, there still exists much room for improvement on how to model them and integrate them effectively. This paper proposes a novel computation model to predict eye fixations, which adopts a multiresolution convolutional neural network (Mr-CNN) to infer these three types of saliency cues from raw image data simultaneously...
November 29, 2016: IEEE Transactions on Neural Networks and Learning Systems
https://www.readbyqxmd.com/read/27891496/interpositional-gap-arthroplasty-by-versatile-pedicled-temporalis-myofascial-flap-in-the-management-of-temporomandibular-joint-ankylosis-a-case-series-study
#16
Vikas Aneja, Rushik Raval, Anupam Bansal, Vinod Kumawat, Jasleen Kaur, Ahemer Arif Shaikh
Temporomandibular Joint (TMJ) ankylosis is a situation in which the mandibular condyle is fused to the glenoid fossa by bone or fibrous tissue. The management of TMJ ankylosis has a complicated chore and it is challenging for the maxillofacial surgeon because of technical hitches and high rate of re-ankylosis. Interpositional gap arthroplasty is one of the modalities for its management. A range of inter-positional materials have been used to avert recurrence after gap arthroplasty in TMJ ankylosis. The aim of this series was to evaluate the effectiveness of the temporomyofacial flap in the treatment of TMJ ankylosis as an interpositional gap arthroplasty...
October 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27887621/pediatric-emergency-department-visits-and-ambient-air-pollution-in-the-u-s-state-of-georgia-a-case-crossover-study
#17
Qingyang Xiao, Yang Liu, James A Mulholland, Armistead G Russell, Lyndsey A Darrow, Paige E Tolbert, Matthew J Strickland
BACKGROUND: Estimating the health effects of ambient air pollutant mixtures is necessary to understand the risk of real-life air pollution exposures. METHODS: Pediatric Emergency Department (ED) visit records for asthma or wheeze (n = 148,256), bronchitis (n = 84,597), pneumonia (n = 90,063), otitis media (n = 422,268) and upper respiratory tract infection (URI) (n = 744,942) were obtained from Georgia hospitals during 2002-2008. Spatially-contiguous daily concentrations of 11 ambient air pollutants were estimated from CMAQ model simulations that were fused with ground-based measurements...
November 25, 2016: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/27867700/mental-stress-assessment-using-simultaneous-measurement-of-eeg-and-fnirs
#18
Fares Al-Shargie, Masashi Kiguchi, Nasreen Badruddin, Sarat C Dass, Ahmad Fadzil Mohammad Hani, Tong Boon Tang
Previous studies reported mental stress as one of the major contributing factors leading to various diseases such as heart attack, depression and stroke. An accurate stress assessment method may thus be of importance to clinical intervention and disease prevention. We propose a joint independent component analysis (jICA) based approach to fuse simultaneous measurement of electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) on the prefrontal cortex (PFC) as a means of stress assessment...
October 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27857857/predictive-parameters-for-the-antecedent-development-of-hip-pathology-associated-with-long-segment-fusions-to-the-pelvis-for-the-treatment-of-adult-spinal-deformity
#19
Merritt D Kinon, Rani Nasser, Jonathan P Nakhla, Owoicho Adogwa, Jessica R Moreno, Michael Harowicz, Terence Verla, Reza Yassari, Carlos A Bagley
BACKGROUND: The surgical treatment of adult scoliosis frequently involves long segment fusions across the lumbosacral joints that redistribute tremendous amounts of force to the remaining mobile spinal segments as well as to the pelvis and hip joints. Whether or not these forces increase the risk of femoral bone pathology remains unknown. The aim of this study is to determine the correlation between long segment spinal fusions to the pelvis and the antecedent development of degenerative hip pathologies as well as what predictive patient characteristics, if any, correlate with their development...
2016: Surgical Neurology International
https://www.readbyqxmd.com/read/27849523/videostory-embeddings-recognize-events-when-examples-are-scarce
#20
Amirhossein Habibian, Thomas Mensink, Cees G M Snoek
This paper aims for event recognition when video examples are scarce or even completely absent. The key in such a challenging setting is a semantic video representation. Rather than building the representation from individual attribute detectors and their annotations, we propose to learn the entire representation from freely available web videos and their descriptions using an embedding between video features and term vectors. In our proposed embedding, which we call Video2vec, the correlations between the words are utilized to learn a more effective representation by optimizing a joint objective balancing descriptiveness and predictability...
November 10, 2016: IEEE Transactions on Pattern Analysis and Machine Intelligence
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