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https://www.readbyqxmd.com/read/29328869/inflammatory-bowel-diseases-and-fermentable-oligosaccharides-disaccharides-monosaccharides-and-polyols-an-overview
#1
Sandra Maria Barbalho, Ricardo de Alvares Goulart, Ana Luíza de Carvalho Aranão, Pamela Grazielle Correa de Oliveira
Inflammatory bowel diseases (IBDs) are mainly represented by ulcerative colitis and Crohn's disease, and the increase in the incidence tends to follow the rapid industrialization and lifestyle of modern societies. FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols) consist of molecules that are poorly absorbed in the small intestine and are fermented by bacteria in the colon leading to symptoms such as bloating, flatulence, diarrhea, and abdominal pain. Reduction of the ingestion of FODMAP could reduce the symptoms and improve the quality of life...
January 12, 2018: Journal of Medicinal Food
https://www.readbyqxmd.com/read/29311037/relationships-among-dietary-intakes-and-persistent-gastrointestinal-symptoms-in-patients-receiving-enzyme-treatment-for-genetic-sucrase-isomaltase-deficiency
#2
Anne Boney, Heather E Elser, Heidi J Silver
BACKGROUND: Sucrose-isomaltase deficiency (SID) remains underdiagnosed. Absent or reduced enzyme activity promotes diarrhea, abdominal bloating, and flatulence from undigested and malabsorbed disaccharides. Frequency and severity of gastrointestinal symptoms may be associated with the type of carbohydrates consumed. OBJECTIVE: To characterize the dietary intakes of patients treated with sacrosidase (Sucraid; QOL Medical) for SID and determine relationships between type of carbohydrates, sacrosidase dose, and gastrointestinal symptoms...
January 5, 2018: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/29234058/relation-of-ultrasound-findings-and-abdominal-symptoms-obtained-with-the-cfabd-score-in-cystic-fibrosis-patients
#3
Harold Tabori, Anke Jaudszus, Christin Arnold, Hans-Joachim Mentzel, Michael Lorenz, Ruth K Michl, Thomas Lehmann, Diane M Renz, Jochen G Mainz
Abdominal symptoms are a hallmark of Cystic fibrosis (CF). Yet, their association with morphological abnormalities of different abdominal organs is still poorly understood. Aim was therefore to relate these symptoms, assessed with a questionnaire, to findings in abdominal ultrasound (US). In 114 CF patients of all ages, findings in US considering seventeen specific parameters were related to abdominal symptoms compiled with our novel CF-specific 26-modal symptom score (CFAbd-Score). US abnormalities were detected in 95% of the patients...
December 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29162372/genetics-environment-and-asthma-associated-with-celiac-disease-in-the-extended-family-of-an-affected-child
#4
R Sigala-Robles, S V Aguayo-Patrón, A M Calderón de la Barca
INTRODUCTION: Celiac disease (CD) is an autoimmune enteropathy associated with gluten ingestion. In extended families of celiac patients that live in close proximity of one another, shared genetic and environmental factors can predispose them to CD. AIM: The aim of this study was to provide evidence about the genetic and environmental factors involved in the development of CD in the extended family of a pediatric patient. METHODS: The medical history, environmental conditions, and participant weight, height, and peripheral blood samples were evaluated...
November 18, 2017: Revista de Gastroenterología de México
https://www.readbyqxmd.com/read/29152247/effects-of-different-protein-sources-on-fermentation-metabolites-and-nutrient-digestibility-of-brachycephalic-dogs
#5
Maria Isabel Gonzalez Urrego, Laura Fantucci de O Matheus, Karine de Melo Santos, Mariane Ceschin Ernandes, Mariana Monti, Danilo Ferreira de Souza, Júlio Cesar de Carvalho Balieiro, Lúcio Francelino Araújo, Cristiana F Ferreira Pontieri, Márcio Antonio Brunetto
Benefits to microbial fermentation in the colon and as a consequence less flatulence can be promoted for the health of adult dogs according to the amount and protein source. The present study evaluated different protein sources in dry food for brachycephalic dogs regarding microbial fermentation and nutrient digestibility. Four dry dog foods with similar protein content were formulated for adult maintenance: poultry meal (PM) diet; wheat gluten (WG) diet; PM + WG diet; and PM + WG + hydrolysed protein (HP) diet...
2017: Journal of Nutritional Science
https://www.readbyqxmd.com/read/29138961/blastocystis-subtypes-isolated-from-irritable-bowel-syndrome-patients-and-co-infection-with-helicobacter-pylori
#6
Ayman A El-Badry, Wegdan M Abd El Wahab, Doaa A Hamdy, Alaa Aboud
Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disease presenting clinically by abdominal pain with alteration of bowel habits. Although IBS has uncertain etiology, chronic gut inflammation due to persistent exposure to an infectious agent including Blastocystis sp. was proposed. The aim of this study was to detect the prevalence of Blastocystis sp. subtype (ST) isolated from stool of IBS patients and to assess Blastocystis sp. and H. pylori co-infection in IBS patients from Beni-Suef Governorate, Egypt...
January 2018: Parasitology Research
https://www.readbyqxmd.com/read/29116394/a-prospective-randomized-pilot-study-evaluating-an-eras-protocol-versus-a-standard-protocol-for-patients-treated-with-radical-cystectomy-and-urinary-diversion-for-bladder-cancer
#7
Sebastian Karl Frees, Jonathan Aning, Peter Black, Werner Struss, Robert Bell, Claudia Chavez-Munoz, Martin Gleave, Alan I So
PURPOSE: There is a lack of evidence demonstrating the benefits of using enhanced recovery after surgery protocols (ERAS). Here, we propose to use a randomized clinical pilot study to demonstrate the benefits and feasibility of implementing ERAS versus standard protocols (SP) in patients undergoing radical cystectomy (RC) and urinary diversion. METHODS: 27 consecutive patients undergoing RC were included in the study. 12 patients were prospectively randomized to follow an ERAS protocol and 15 patients followed an SP...
November 7, 2017: World Journal of Urology
https://www.readbyqxmd.com/read/29101597/randomized-placebo-controlled-pilot-trial-of-omega-3-fatty-acids-for-prevention-of-aromatase-inhibitor-induced-musculoskeletal-pain
#8
Maryam B Lustberg, Tonya S Orchard, Raquel Reinbolt, Rebecca Andridge, Xueliang Pan, Martha Belury, Rachel Cole, Amanda Logan, Rachel Layman, Bhuvaneswari Ramaswamy, Robert Wesolowski, Michael Berger, Elaine Patterson, Charles Loprinzi, Charles L Shapiro, Lisa Yee
PURPOSE: Aromatase inhibitor (AI)-induced joint symptoms negatively impact drug adherence and quality of life in breast cancer survivors. Mechanisms underlying symptoms may include inflammation. It is hypothesized that n - 3 polyunsaturated fatty acids (PUFAs) have anti-inflammatory properties and may reduce symptoms. METHODS: We conducted a randomized, double-blind, placebo-controlled study comparing 4.3 g/day n - 3 PUFA supplements vs placebo for 24 weeks in postmenopausal breast cancer patients starting adjuvant AIs...
November 3, 2017: Breast Cancer Research and Treatment
https://www.readbyqxmd.com/read/29070042/effects-of-cow-s-milk-beta-casein-variants-on-symptoms-of-milk-intolerance-in-chinese-adults-a-multicentre-randomised-controlled-study
#9
Mei He, Jianqin Sun, Zhuo Qin Jiang, Yue Xin Yang
BACKGROUND: A major protein component of cow's milk is β-casein. The most frequent variants in dairy herds are A1 and A2. Recent studies showed that milk containing A1 β-casein promoted intestinal inflammation and exacerbated gastrointestinal symptoms. However, the acute gastrointestinal effects of A1 β-casein have not been investigated. This study compared the gastrointestinal effects of milk containing A1 and A2 β-casein versus A2 β-casein alone in Chinese adults with self-reported lactose intolerance...
October 25, 2017: Nutrition Journal
https://www.readbyqxmd.com/read/29059642/diagnostic-algorithm-and-peculiarities-of-monitoring-for-infants-with-disorders-of-the-gastrointestinal-tract
#10
Tetyana O Kryuchko, Inna M Nesina, Olha Ya Tkachenko
INTRODUCTION: The most common medical conditions in infants, which belong to pediatric and gastroenterological disease areas, are functional gastrointestinal disorders, food hypersensitivity and food allergy. First of all, these symptoms can disguise lactase deficiency, cow's milk protein allergy, eosinophilic gastroenteritis, allergic proctocolitis, gastrointestinal manifestations of atopic dermatitis, functional disorders of gastrointestinal and biliary tract, etc. The aim of our study was to develop an algorithm of monitoring for infants with disorders of the gastrointestinal tract and to study the efficacy of probiotic and enzyme replacement therapy...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/29037690/multi-response-modeling-of-reaction-diffusion-to-explain-alpha-galactoside-behavior-during-the-soaking-cooking-process-in-cowpea
#11
Fanny Coffigniez, Aurélien Briffaz, Christian Mestres, Pascaline Alter, Noel Durand, Philippe Bohuon
A modelling approach was developed to better understand the behavior of the flatulence-causing oligosaccharides in cowpea seeds during isothermal water soaking-cooking process. Concentrations of verbascose, stachyose and raffinose were measured both in the seed and in the soaking water during the process (T=30, 60 and 95°C). A reaction-diffusion model was built for the three considered alpha-galactosides both in the seed and in the soaking water, together with a model of water transport in the seed. The model reproduced coupled reaction-diffusion of alpha-galactosides during the soaking-cooking process with a good fit...
March 1, 2018: Food Chemistry
https://www.readbyqxmd.com/read/29034180/significance-of-fermentation-process-on-biochemical-properties-of-phaseolus-vulgaris-red-beans
#12
Anteneh Worku, Omprakash Sahu
Phaseolus vulgaris L. beans have been characterized as a nearly perfect food in all around the world. It is consider functional in terms of providing nutrients and energy to sustain daily life. Red bean contain high protein, mineral, fibres and chemically diverse micronutrient composition, which can be affected by processing. The main aim of this work is to investigate the effect of open and controlled fermentation on the proximate composition, mineral elements, antinutritional factors and flatulence- causing oligosaccharides of a domesticated bean (Anger, conscope and Loko)...
December 2017: Biotechnology Reports
https://www.readbyqxmd.com/read/29023061/protective-role-of-achillea-biebersteinii-pretreatment-on-dimethoate-induced-oxidative-stress-in-guinea-pigs-liver
#13
Yahya Saleh Al-Awthan, Mohamed Ali Al-Duais, Amany Abdulfatah Hazeb, Waleed Ahmed Alril
OBJECTIVE: The present study investigated the influence of Achillea biebersteinii (Ab), a medicinal herb used widely in Yemeni's folk medicine as analgesic, antipyretic, against diarrhea and flatulence and for liver diseases, on the liver antioxidant potential of guinea pigs acutely intoxicated with dimethoate pesticide (DM). MATERIALS AND METHODS: Animals were administered with Ab aqueous extract (50 and 100 mg kg-1 b.wt., orally) or silymarin (100 mg kg-1 b.wt...
2017: Pakistan Journal of Biological Sciences: PJBS
https://www.readbyqxmd.com/read/28974589/the-efficacy-of-a-low-fat-diet-to-manage-the-symptoms-of-bile-acid-malabsorption-outcomes-in-patients-previously-treated-for-cancer
#14
Amy Jackson, Amyn Lalji, Mohammed Kabir, Ann Muls, Caroline Gee, Susan Vyoral, Clare Shaw, H Jervoise N Andreyev
Dietary fat ingestion triggers bile secretion into the gastrointestinal tract. Bile acid malabsorption affects >1% of the population, causing loose stool and other gastrointestinal symptoms. The diagnosis is frequently missed. Treatments are often considered ineffective. We evaluated low-fat diets for managing gastrointestinal symptoms in these patients. All patients reporting type 6 or 7 stool were offered a selenium-75 homocholic acid taurine (SeHCAT) scan. Prospective data in patients with 7-day scan retention <20% were analysed...
October 2017: Clinical Medicine: Journal of the Royal College of Physicians of London
https://www.readbyqxmd.com/read/28970147/fructans-exacerbate-symptoms-in-a-subset-of-children-with-irritable-bowel-syndrome
#15
Bruno Pedro Chumpitazi, A R McMeans, A Vaughan, A Ali, S Orlando, A Elsaadi, R J Shulman
BACKGROUND & AIMS: Dietary fructans exacerbate symptoms in some, but not all, adults with irritable bowel syndrome (IBS). We sought to determine whether fructans worsen symptoms in children with IBS and whether clinical and psychosocial factors, and/or gas production, can identify those who are fructan sensitive. METHODS: We performed a double-blind placebo-controlled (maltodextrin) cross-over trial of 23 children with IBS, based on pediatric Rome III criteria, from September 2014 through December 2016...
September 29, 2017: Clinical Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28969118/spectrum-of-parasitic-infections-in-patients-with-diarrhoea-attending-a-tertiary-care-hospital-in-western-rajasthan-india
#16
Kumar Saurabh, Vijaya Lakshmi Nag, Saroj Dash, Anand Kumar Maurya, Vivek Hada, Richa Agrawal, Himanshu Narula, Anuradha Sharma
INTRODUCTION: Owing to the poor socioeconomic conditions and lack of sanitary hygiene, a large number of population in developing countries remain under constant threat of different parasitic infections causing severe morbidity and mortality. Enough measures to prevent and reduce the disease burden are still to be undertaken. AIM: Aim of the study was to determine the spectrum of parasitic infections in patients with complaints of diarrhoea and other gastrointestinal symptoms attending a tertiary care hospital in Western Rajasthan, India...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28956139/the-effects-of-activating-almonds-on-consumer-acceptance-and-gastrointestinal-tolerance
#17
Heidi Taylor, Kirsten Webster, Andrew R Gray, Siew Ling Tey, Alex Chisholm, Karl Bailey, Shivani Kumari, Rachel C Brown
PURPOSE: Recommendations to soak nuts prior to consumption to reduce phytate concentrations and improve gastrointestinal tolerance have received much attention in the popular press. This is despite no supporting scientific evidence for the practice. There is also a lack of information about how soaking nuts might affect consumer acceptability. This study primarily assessed the effects of soaking almonds on consumer acceptance and secondly assessed effects on gastrointestinal tolerance...
September 27, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28954842/whole-grain-rye-and-wheat-affect-some-markers-of-gut-health-without-altering-the-fecal-microbiota-in-healthy-overweight-adults-a-6-week-randomized-trial
#18
Stine Vuholm, Dennis S Nielsen, Kia Nøhr Iversen, Julie Suhr, Peter Westermann, Lukasz Krych, Jens Rikardt Andersen, Mette Kristensen
Background: Whole grains have shown potential for improving gut health, but evidence comparing different whole-grain types is lacking.Objective: We investigated whether whole-grain wheat (WGW) and whole-grain rye (WGR) improve gut health in different ways compared to refined wheat (RW), with the primary outcomes of microbiota composition and gastrointestinal (GI) symptoms.Methods: In a randomized parallel trial, 70 healthy adults (in means ± SDs; aged 51.0 ± 9.4 y, body mass index [BMI (in kg/m(2))] 27.8 ± 1...
September 27, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28937980/methanobrevibacter-attenuation-via-probiotic-intervention-reduces-flatulence-in-adult-human-a-non-randomised-paired-design-clinical-trial-of-efficacy
#19
Minseok Seo, Jaeyoung Heo, Joon Yoon, Se-Young Kim, Yoon-Mo Kang, Jihyun Yu, Seoae Cho, Heebal Kim
TRIAL DESIGN: The aim of this study was to investigate which of the gut microbes respond to probiotic intervention, as well as study whether they are associated with gastrointestinal symptoms in a healthy adult human. For the experimental purpose, twenty-one healthy adults were recruited and received probiotic mixture, which is composed of five Lactobacilli strains and two Bifidobacteria strains, once a day for 60 days. Defecation survey and Bioelectrical Impedance Analysis were conducted pre- and post-administration to measure phenotypic differences...
2017: PloS One
https://www.readbyqxmd.com/read/28894218/lactate-utilizing-community-is-associated-with-gut-microbiota-dysbiosis-in-colicky-infants
#20
Van T Pham, Christophe Lacroix, Christian P Braegger, Christophe Chassard
The aetiology of colic, a functional gastrointestinal disorder in infants, is not yet resolved. Different mechanisms have been suggested involving the gut microbiota and intermediate metabolites such as lactate. Lactate can be metabolized by lactate-utilizing bacteria (LUB) to form different end-products. Using a functional approach, we hypothesized that H2 production and accumulation by LUB is associated with the development of colic. The LUB communities in the feces of forty infants, including eight colicky infants, were characterized using a combination of culture- and molecular-based methods, and metabolite concentrations were measured by HPLC...
September 11, 2017: Scientific Reports
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