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Aesthetic injections

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https://www.readbyqxmd.com/read/28731160/adipose%C3%A2-derived-stem-cells-and-hyaluronic-acid-based-gel-compatibility-studied-in-vitro
#1
Jiayan Guo, Shu Guo, Yuxin Wang, Yanqiu Yu
Minimally invasive aesthetic and cosmetic procedures have increased in popularity. Injectable dermal fillers provide soft tissue augmentation, improve facial rejuvenation and wrinkles, and correct tissue defects. To investigate the use of adipose‑derived stem cells integrated with a hyaluronic acid based gel as a dermal filler, the present study used cytotoxicity studies, proliferation studies, adipogenic and osteogenic differentiation, apoptosis assays and scanning electron microscopy. Although hyaluronic acid induced low levels of apoptosis in adipose‑derived stem cells, its significantly promoted proliferation of adipose‑derived stem cells...
July 21, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28726351/correction-of-horizontal-neck-lines-our-preliminary-experience-with-hyaluronic-acid-fillers
#2
Soo-Keun Lee, Hei Sung Kim
BACKGROUND: There is an increasing trend shifting the esthetic focus downward from the face with a significant number of new treatments aimed at the aging neck. Hyaluronic acid (HA) filler injection is widely performed into the horizontal neck lines in Korea, but there are few reports assessing its effectiveness. OBJECTIVE: We aimed to evaluate the efficacy and safety of HA filler injection in the treatment of horizontal neck lines. PATIENTS AND METHODS: A retrospective chart review was performed on cases of horizontal neck lines treated with HA fillers...
July 20, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28702976/a-new-hyaluronic-acid-polymer-in-the-augmentation-and-restoration-of-labia-majora
#3
N Zerbinati, R G Haddad, A Bader, R Rauso, E D'Este, G Cipolla, A Calligaro, P Gonzalez, S Salvatore, D Serafin
Aesthetic surgery of female external genitalia has gained increasing popularity over the past decade, with reduction of the labia minora (labiaplasty) being the procedure most commonly requested and performed. Female external genitalia lose elasticity and volume with age, but few studies describe the techniques for labia majora augmentation. Currently, very few studies have investigated the effectiveness and safety of labia majora augmentation with hyaluronic acid (HA) injection. This study aims to evaluate the effectiveness and safety of labia majora augmentation with hyaluronic acid filler injection...
July 13, 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28702187/procedure-applications-and-outcomes-of-autologous-fat-grafting
#4
REVIEW
Francesco Simonacci, Nicolò Bertozzi, Michele Pio Grieco, Eugenio Grignaffini, Edoardo Raposio
OBJECTIVE: To systematically review the procedure, applications, and outcomes of autologous fat grafting, a promising technique with various clinical applications. PATIENTS AND METHODS: Literature review of publications concerning autologous fat grafting. RESULTS: Since its introduction, lipofilling has become increasingly popular; however, its results are variable and unpredictable. Several modifications have been made to the procedures of fat harvesting, processing, and injecting...
August 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28697217/expert-consensus-on-absorbable-advanced-suspension-technology-for-facial-tissue-repositioning-and-volume-enhancement
#5
Mark S Nestor, Glynis Ablon, Anneke Andriessen, Julius Few, Michael H Gold, David J Goldberg, Paul Lorenc, Stephen Mandy, Susan H Weinkle
<p>BACKGROUND: Signs of facial aging include wrinkles, loss of subcutaneous volume, decreased tone, texture, and sagging of the skin. The objective of this review is to determine whether facial suspension absorbable sutures are a safe and effective modality for facial rejuvenation.</p> <p>METHOD: A group of US plastic surgeons and dermatologists who practice medical aesthetics convened to review evidence obtained from literature searches and to reach a consensus on clinical practice guidelines for the use of facial absorbable suspension sutures...
July 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28691479/effect-of-platelet-reach-plasma-on-fibroblast-primary-culture-gene-expression-evaluation
#6
V Candotto, A Palmieri, F Cura, F J Silvestre, D Lauritano, R M Gaudio, A Baj, A B Giannì
To correct skin imperfections, aesthetic medicine today makes use of injectable dermal fillers that allow filling skin by increasing the volume of soft tissue. Currently, there are many fillers usable for their excellent biocompatibility and low allergic reactions that ensure good results and good compliance. Among these, the most widely used filler is Human Plasma, obtained by centrifugation from patient blood and processed through cycles of centrifugation and heating, until it becomes a gel. In this work, we evaluated the effect of the Plasma on fibroblasts behavior in terms of cell viability, survival, growth and collagen production...
April 2017: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/28675618/restoring-jawline-contour-with-calcium-hydroxylapatite-a%C3%A2-prospective-observational-study
#7
Martine Baspeyras, Jean-Marie Dallara, Hugues Cartier, Marie-Hélène Charavel, Laurent Dumas
BACKGROUND: Jawline reshaping by replacing volume has become an indispensable component of modern facial rejuvenation. AIM: To evaluate calcium hydroxylapatite (CaHA) for the treatment of an aging jawline in a routine setting. METHODS: Five investigators enrolled 35 subjects requesting jawline rejuvenation with CaHA. Injections were performed according to investigators usual practice. Baseline and post-treatment scores were evaluated using Merz Aesthetics Scales®...
July 4, 2017: Journal of Cosmetic Dermatology
https://www.readbyqxmd.com/read/28665146/pressure-and-dose-controlled-transcutaneous-pneumatic-injection-of-hypertonic-glucose-solution-for-the-treatment-of-atrophic-skin-disorders
#8
Heesu Kim, Kwang Ho Yoo, Zhenlong Zheng, Sung Bin Cho
Background Needleless transcutaneous pneumatic injections (TPI) are a minimally invasive way to deliver solution into the skin for therapeutic purposes. The suggested action mechanisms of TPI therapy include mechanical stimulation, immediate tissue shrinkage, and late wound healing. Methods Thirteen Korean patients were treated with TPI for atrophic skin disorders, including acne scars, striae albae, post-furuncle or carbuncle scars, and horizontal wrinkles with lipoatrophy. At each TPI treatment session, a single pass was made along on the atrophic skin lesions without overlapping...
June 30, 2017: Journal of Cosmetic and Laser Therapy: Official Publication of the European Society for Laser Dermatology
https://www.readbyqxmd.com/read/28654586/botulinum-toxin-for-neck-rejuvenation-assessing-efficacy-and-redefining-patient-selection
#9
Samer F Jabbour, Elio G Kechichian, Cyril J Awaida, Roland R Tomb, Marwan W Nasr
BACKGROUND: The "Nefertiti lift" consists of injecting the platysmal bands and the inferior border of the mandible with botulinum toxin. No clinical trial has evaluated its effect on the different lower face and neck aging components, and little is known about the clinical characteristics that predict treatment success. METHODS: Patients were injected with abobotulinumtoxinA along the inferior border of the mandible and into the platysmal bands. Using standardized preinjection and postinjection photographs, the jowls, marionette lines, oral commissures, neck volume, and platysmal bands at maximal contraction and at rest were assessed with validated photonumeric scales...
July 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28652795/minimal-recovery-time-needed-to-return-to-social-engagement-following-nasolabial-fold-correction-with-hyaluronic-acid-fillers-produced-with-xpreshan-technology
#10
Arthur Swift, Erika von Grote, Brandie Jonas, Alessandra Nogueira
INTRODUCTION: The appeal of hyaluronic acid fillers for facial soft tissue augmentation is attributable to both an immediate aesthetic effect and relatively short recovery time. Although recovery time is an important posttreatment variable, as it impacts comfort with appearance and perceived treatment benefit, it is not routinely evaluated. Natural-looking aesthetic outcomes are also a primary concern for many patients. MATERIALS AND METHODS: A single-center, noncomparative study evaluated the time (in hours) until subjects return to social engagement (RtSE) following correction of moderate and severe nasolabial folds (NLFs) with RR (Restylane(®) Refyne)(®) and RD (Restylane Defyne), respectively...
2017: Clinical, Cosmetic and Investigational Dermatology
https://www.readbyqxmd.com/read/28642791/efficacy-and-safety-of-ultrasound-guided-percutaneous-polidocanol-sclerotherapy-in-benign-cystic-thyroid-nodules-preliminary-results
#11
Xiaohua Gong, Qi Zhou, Fang Wang, Wenjun Wu, Xiaojun Chen
OBJECTIVE: To evaluate the efficacy and safety of percutaneous polidocanol injection (PPI) in treating cystic thyroid nodules. MATERIALS AND METHODS: A total of 158 cystic or predominantly cystic thyroid nodules (>80% cystic component) in 143 patients were evaluated. 114 patients with compressive symptoms or aesthetic complaints were offered PPI. 44 individuals without compressive symptoms and aesthetic complaints who were only followed up clinically were used as the control group...
2017: International Journal of Endocrinology
https://www.readbyqxmd.com/read/28628683/understanding-the-shape-of-forehead-lines
#12
Milad Moqadam, Konstantin Frank, Christina Handayan, Mustafa Hakami, Fahd Benslimane, Robert H Gotkin, Neil S Sadick, Sebastian Cotofana
<p>Background: Individualized neuromodulator injections of the forehead are increasingly important to maximize patient safety and satisfaction and to yield the best aesthetic outcome. To assess the location of maximal muscle contraction, it would beneficial to relate the shape and location of the forehead lines to the morphology of the underlying frontalis muscle.</p> <p>Materials and Methods: We investigated the shape of forehead lines and their relationship to the morphology of the underlying frontalis muscle using anatomic dissection in a sample of 31 human body donors, with a mean age at death of 77...
May 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28612001/botulinum-toxin-off-label-use-in-dermatology-a-review
#13
REVIEW
Anna Campanati, Emanuela Martina, Katia Giuliodori, Veronica Consales, Ivan Bobyr, Annamaria Offidani
BACKGROUND: Botulinum toxin is a neurotoxin produced by the bacterium Clostridium botulinum which causes a flaccid muscle paralysis. It is currently used for aesthetic treatments and in the focal hyperhidrosis. Recently, botulinum toxin has also been used experimentally in many other dermatological conditions with good results. OBJECTIVE: To review and analyze the possible botulinum toxin off-label applications published. METHODS: A retrospective review of the published data was conducted...
March 2017: Skin Appendage Disorders
https://www.readbyqxmd.com/read/28585321/delayed-onset-filler-complication-two-case-reports-and-literature-review
#14
Hyeree Kim, Sang Hyun Cho, Jeong Deuk Lee, Hei Sung Kim
Soft tissue augmentation by fillers has become a popular cosmetic tool to offer rejuvenation and aesthetic improvement. Its results are comparable to those previously achieved only by plastic surgery. However, marked increase of filler procedures is associated with a great number of complications. Complications associated with filler injection might have early onset (within days) or late onset (after weeks to years). Delayed complications include infections, foreign body granulomatous reaction, migration of filler material, persistent discoloration, and scarring...
June 6, 2017: Dermatologic Therapy
https://www.readbyqxmd.com/read/28567474/impending-facial-skin-necrosis-and-ocular-involvement-after-dermal-filler-injection-a-case-report
#15
André Salval, Francesco Ciancio, Andrea Margara, Stefano Bonomi
Demand for non-surgical rejuvenating procedure is constantly increasing due to the aging population, increasing expense of aesthetics and beauty procedures, introduction of new applications and rising demand for noninvasive aesthetic procedures over surgical procedures. Skin necrosis is a rare but severe potential complication. It is caused by impediment of the blood supply to the skin area by compression and/or obstruction of the vessel with filler material, and/or direct injury to the vessel. We report the case of a young patient who presented an acute and severe complication after a dermal filler injection by an unlicensed therapist...
May 31, 2017: Aesthetic Plastic Surgery
https://www.readbyqxmd.com/read/28562435/calcium-hydroxylapatite-dermal-filler-for-treatment-of-dorsal-hand-volume-loss-results-from-a-12-month-multicenter-randomized-blinded-trial
#16
Mitchel P Goldman, Amir Moradi, Michael H Gold, Daniel P Friedmann, Kaveh Alizadeh, Jeffrey M Adelglass, Bruce E Katz
BACKGROUND: Calcium hydroxylapatite (CaHA) microspheres suspended in a carrier gel is an opaque dermal filler that has been used to provide immediate volume correction in the dorsal hands. OBJECTIVE: To assess the safety and effectiveness of CaHA for the correction of volume loss in the hands up to 12 months. MATERIALS AND METHODS: This multicenter, controlled, single-blind study (NCT01832090) included 114 subjects randomized 3:1 to CaHA treatment and untreated control groups...
May 25, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28562432/a-two-phase-pilot-study-to-evaluate-the-safety-and-tolerability-of-an-in-situ-polymerizing-collagen
#17
Christopher Inglefield, Rebecca Rone-McCrate, Robert Brooks, Jiaxun Zhu, Sheila Grant, Dale P DeVore
BACKGROUND: Demand for collagen-based fillers has declined primarily because of limited long-term clinical benefit and the introduction of hyaluronic acid compositions. In situ polymerizing collagen is a noncrosslinked solution of porcine collagen containing a collagenase shield that undergoes fibrillogenesis on injected into tissues forming a natural matrix. OBJECTIVE: Conduct a prospective, single-center, dual-phase open-label study in 8 subjects to evaluate the safety, tolerability, and efficacy of the porcine collagen composition...
May 25, 2017: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/28543874/ex-vivo-magnetic-resonance-imaging-using-hyaluronic-acid-fillers-differences-between-monophasic-and-biphasic-fillers
#18
M J Kim, W-J Moon, M S Hur, S H Han, Y W Lee, Y B Choe, K J Ahn
BACKGROUND/PURPOSE: Hyaluronic acid (HA) is an anionic, non-sulfated glycosaminoglycan distributed throughout the human skin and injectable HA fillers are the most commonly used in aesthetic field. This study aimed to determine if differences in physical characteristics of HA products (monophasic or biphasic fillers) affect the patterns of magnetic resonance imaging (MRI). METHODS: Twenty biphasic fillers and nine monophasic fillers were obtained from a commercial source, and examined with a 3...
May 25, 2017: Skin Research and Technology
https://www.readbyqxmd.com/read/28538563/the-six-step-lower-blepharoplasty-using-fractionated-fat-to-enhance-blending-of-the-lid-cheek-junction
#19
Ronnie A Pezeshk, David A Sieber, Rod J Rohrich
Lower lid blepharoplasty is one of the most complex procedures performed by plastic surgeons and may cause significant long-term sequelae, including inadequate aesthetic outcomes if not performed with a thorough understanding of anatomy and proper technique. The authors' practice is consistently evolving to deliver the highest quality results for their patients. The purpose of this article is to introduce an additional sixth step to the lower lid blepharoplasty procedure involving the targeted injection of fractionated fat to better blend the lid-cheek junction...
June 2017: Plastic and Reconstructive Surgery
https://www.readbyqxmd.com/read/28538556/a-randomized-controlled-multicenter-study-of-juv%C3%A3-derm-voluma-for-enhancement-of-malar-volume-in-chinese-subjects
#20
Dong Li, Xiaojun Wang, Yan Wu, Jiaming Sun, Qin Li, Shuzhong Guo, Yi Jia, Diane K Murphy
BACKGROUND: Hyaluronic acid gels are used to restore volume to the midface, but there are few data published on this use in Asian subjects. METHODS: This study evaluated the safety and effectiveness in Chinese subjects of Juvéderm Voluma, a 20-mg/ml hyaluronic acid gel formulated for midface volumizing. This prospective, multicenter study randomized 119 subjects aged 18 years or older to a treatment group and 27 subjects to a no-treatment control group. The primary effectiveness endpoint was the objectively measured magnitude of change from baseline in volume of the midface area (right and left combined) calculated by digital analysis at month 6 using three-dimensional images for all subjects in both groups...
June 2017: Plastic and Reconstructive Surgery
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