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https://www.readbyqxmd.com/read/29152325/changes-of-intestinal-microbiota-composition-and-diversity-in-very-low-birth-weight-infants-related-to-strategies-of-nec-prophylaxis-protocol-for-an-observational-multicentre-pilot-study
#1
Stefan Kurath-Koller, Christine Moissl-Eichinger, Gregor Gorkiewicz, Raimund Kraschl, Claudia Kanduth, Barbara Hopfer, Berndt Urlesberger, Bernhard Resch
Background: At the Division of Neonatology, Department of Paediatrics, Medical University Graz, a unique regimen of necrotizing enterocolitis (NEC) prophylaxis in preterm infants showing a < 1500 g birth weight (i.e. very low birth weight, VLBW) is used. The regimen includes oral antibiotic and antifungal therapy and probiotic preparations as well as a standardised feeding regimen. The incidence of NEC in preterm infants treated by this regimen has been shown to be lower, reflecting 0...
2017: Pilot and Feasibility Studies
https://www.readbyqxmd.com/read/29144490/neonatal-lung-ultrasound-exam-guidelines
#2
D Kurepa, N Zaghloul, L Watkins, J Liu
Point-of-care ultrasound (POC-US) is increasingly used especially in emergency and critical-care medicine. It is focused, quick and does not expose patients to ionizing radiation. It encompasses all organ systems and has well-defined indications. Lung ultrasound (LUS) represents one of the most exciting applications in the field of POC-US. It is particularly important to emphasize the role of LUS in neonatology due to the specific pathology inherent in lung immaturity as well as in the particular sensitivity of neonates to repeated radiation exposure...
November 16, 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/29142784/the-value-of-implementing-multidisciplinary-perinatal-care-conference-in-the-private-practice-setting
#3
Robert C Johnston, Sina Haeri, Richard T Hale, William Lindsley, Annette McCormick, Eric Su
Objective  The objective of this study was to estimate the impact of multidisciplinary (Multi-D) perinatal care conference (PCC) implementation in the private practice setting. Methods  After the initial 12-month period following implementation of the monthly PCC by private maternal-fetal medicine and neonatology practitioners, conference attendees were asked to completed a modified version of the Attitudes Toward Health Care Teams Scale, involving 19 questions assessing their attitudes and opinions toward Multi-D team care on a five-point Likert's scale...
October 2017: American Journal of Perinatology Reports
https://www.readbyqxmd.com/read/29137711/novel-free-radical-mediated-lipid-peroxidation-biomarkers-in-newborn-plasma
#4
Ángel Sánchez-Illana, Sudhin Thayyil, Paolo Montaldo, Dorothea Jenkins, Guillermo Quintás, Camille Oger, Jean-Marie Galano, Claire Vigor, Thierry Durand, Máximo Vento, Julia Kuligowski
Oxidative stress derived from perinatal asphyxia appears to be closely linked to neonatal brain damage and lipid peroxidation biomarkers have shown to provide predictive power of oxidative stress related pathologies in situations of hypoxia and reoxygenation in the newborn. The objective of this work was to develop and validate of a comprehensive liquid chromatography tandem mass spectrometry approach for the quantitative profiling of 28 isoprostanoids in newborn plasma samples covering a broad range of lipid peroxidation product classes...
December 15, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/29132234/upcycling-umbilical-cords-bridging-regenerative-medicine-with-neonatology
#5
Alvaro Moreira, Yasmeen Alayli, Saloni Balgi, Caitlyn Winter, Samuel Kahlenberg, Shamimunisa Mustafa, Peter Hornsby
Preterm birth is a major health concern that affects 10% of all worldwide deliveries. Many preterm infants are discharged from the hospital with morbidities that lead to an increased risk for neurodevelopmental impairment, recurrent hospitalizations, and life-long conditions. Unfortunately, the treatment of these conditions is palliative rather than curative, which calls for novel and innovative strategies. Progress in regenerative medicine has offered therapeutic options for many of these conditions. Specifically, human umbilical cord mesenchymal stem cells (MSCs) and cord blood (UCB) cells have shown promise in treating adult onset diseases...
November 13, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29131918/neonatology-a-variety-of-presentations-diagnoses-and-treatments
#6
EDITORIAL
Alison Chu
No abstract text is available yet for this article.
November 1, 2017: Pediatric Annals
https://www.readbyqxmd.com/read/29131022/an-echocardiographic-screening-program-helps-to-identify-pulmonary-hypertension-in-extremely-low-birthweight-infants-with-and-without-bronchopulmonary-dysplasia-a-single-center-experience
#7
Katrin Mehler, Floris E Udink Ten Cate, Titus Keller, Ursula Bangen, Angela Kribs, André Oberthuer
BACKGROUND: Pulmonary hypertension (PH) affects 1 in 6 infants with a birthweight <1,000 g (extremely low birthweight; ELBW) and is frequently associated with bronchopulmonary dysplasia (BPD). If untreated, the mortality rates of the disease are high. OBJECTIVES: The aim of this study was to characterize risk factors for PH in ELBW infants and to describe the timing of onset of the disease by setting up a screening program. METHODS: ELBW infants treated at the Department of Neonatology (level III neonatal intensive care unit at the University of Cologne Medical Centre, Germany) between January 2010 and March 2015 were included...
November 8, 2017: Neonatology
https://www.readbyqxmd.com/read/29130703/nutritional-practices-in-very-low-birth-weight-infants-a-national-survey
#8
Miguel Sáenz de Pipaón, Ricardo Closa, María Gormaz, Marcos Linés, Eduardo Narbona, Gerardo Rodríguez-Martínez, José Uberos, Carlos Zozaya, María L Couce
BACKGROUND: Significant efforts have been made to improve the nutritional support of very preterm infants. Large surveys may help to know the nutritional practices for preterm infants in neonatal units and identify if they are in line with the current guidelines. METHODS: A multicentre nationwide web-based survey on clinical feeding practices in very low birth weight (VLBW) infants was conducted in tertiary neonatal hospitals that admit infants with a birth weight < 1,500 g and/or a gestational age of < 32 weeks...
October 24, 2017: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
https://www.readbyqxmd.com/read/29128922/causes-of-renal-oligohydramnios-impact-on-prenatal-counseling-and-postnatal-outcome
#9
EDITORIAL
Sebastian Loos, Markus J Kemper
The presence of renal oligohydramnios (ROH) in a fetus has been associated in the past with a poor prognosis for survival, although recent studies have shown that survival has improved considerably due to the advances in neonatology and pediatric nephrology. In an article recently published in Pediatric Nephrology, evaluation of a large series by Mehler and colleagues confirms the improved prognosis, showing a survival rate of 32 of 38 (84%). In addition, only 12 of 35 (34%) neonates required renal replacement therapy...
November 11, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29117261/diagnostic-accuracy-of-the-roche-septifast-pcr-system-for-the-rapid-detection-of-blood-pathogens-in-neonatal-sepsis-a-prospective-clinical-trial
#10
Julia Straub, Helga Paula, Michaela Mayr, David Kasper, Ojan Assadian, Angelika Berger, Judith Rittenschober-Böhm
INTRODUCTION: Diagnosis of neonatal sepsis remains a major challenge in neonatology. Most molecular-based methods are not customized for neonatal requirements. The aim of the present study was to assess the diagnostic accuracy of a modified multiplex PCR protocol for the detection of neonatal sepsis using small blood volumes. METHODS: 212 episodes of suspected neonatal late onset sepsis were analyzed prospectively using the Roche SeptiFast® MGRADE PCR with a modified DNA extraction protocol and software-handling tool...
2017: PloS One
https://www.readbyqxmd.com/read/29111298/improving-neonatal-care-with-the-help-of-veteran-resource-parents-an-overview-of-current-practices
#11
Claude Julie Bourque, Sonia Dahan, Ginette Mantha, Kate Robson, Martin Reichherzer, Annie Janvier
Over the past decade, veteran parents who have lived a neonatal intensive care unit (NICU) experience have become increasingly involved as 'resource parents' to provide peer-to-peer support to "new" NICU parents. These parents can provide a unique form of support to new parents. They can also assume other roles in clinical care, research, administration and/or teaching, but those roles are rarely described in the literature. This article reviews many of the activities performed by resource parents in neonatology...
October 27, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29100893/-late-preterm-infants-in-spain-experience-of-the-34-36-neonatal-group
#12
Mercedes García-Reymundo, Xavier Demestre, M José Calvo, Gemma Ginovart, Ana Jiménez, José Antonio Hurtado
INTRODUCTION: Late preterm (LP) infants (34 -36 weeks of gestation) are the largest group of preterm infants and also the least studied so far. In order to improve their care and reduce the impact of their increased morbidity and mortality, it is essential to know the current situation in Spain. POPULATION AND METHOD: Clinical-epidemiological variables of the LP population of 34 participating hospitals were prospectively collected from 1 April 2011 to 31 March 2016, and were then compared with the Minimum Perinatal Data Set for term births in the database...
October 31, 2017: Anales de Pediatría: Publicación Oficial de la Asociación Española de Pediatría (A.E.P.)
https://www.readbyqxmd.com/read/29100533/effectiveness-of-interventions-during-nicu-hospitalization-on-the-neurodevelopment-of-preterm-infants-a-systematic-review-protocol
#13
Marilyn Aita, Robyn Stremler, Nancy Feeley, Andréane Lavallée, Gwenaëlle De Clifford-Faugère
BACKGROUND: Previous systematic reviews have examined preterm infants' long-term neurodevelopment after neonatal intensive care unit (NICU) discharge, although none have explored the effectiveness of interventions on preterm infants' neurodevelopment during NICU hospitalization. The aim of this review is to evaluate whether interventions, i.e., sensory stimulation, parental involvement, and control of environment, improve preterm infants' neurodevelopment during their NICU hospitalization...
November 3, 2017: Systematic Reviews
https://www.readbyqxmd.com/read/29096709/strategies-for-preventing-group-b-streptococcal-infections-in-newborns-a-nation-wide-survey-of-italian-policies
#14
Chryssoula Tzialla, Alberto Berardi, Claudio Farina, Pierangelo Clerici, Alessandro Borghesi, Elsa Viora, Paolo Scollo, Mauro Stronati
BACKGROUND: There are no Italian data regarding the strategies for preventing neonatal group B streptococcal (GBS) infection. We conducted a national survey in order to explore obstetrical, neonatal and microbiological practices for the GBS prevention. METHODS: Three distinct questionnaires were sent to obstetricians, neonatologists and microbiologists. Questionnaires included data on prenatal GBS screening, maternal risk factors, intrapartum antibiotic prophylaxis, microbiological information concerning specimen processing and GBS antimicrobial susceptibility...
November 2, 2017: Italian Journal of Pediatrics
https://www.readbyqxmd.com/read/29081997/implementation-of-effective-practices-in-health-facilities-a-systematic-review-of-cluster-randomised-trials
#15
Emma R Allanson, Özge Tunçalp, Joshua P Vogel, Dina N Khan, Olufemi T Oladapo, Qian Long, Ahmet Metin Gülmezoglu
BACKGROUND: The capacity for health systems to support the translation of research in to clinical practice may be limited. The cluster randomised controlled trial (cluster RCT) design is often employed in evaluating the effectiveness of implementation of evidence-based practices. We aimed to systematically review available evidence to identify and evaluate the components in the implementation process at the facility level using cluster RCT designs. METHODS: All cluster RCTs where the healthcare facility was the unit of randomisation, published or written from 1990 to 2014, were assessed...
2017: BMJ Global Health
https://www.readbyqxmd.com/read/29073796/death-audit-in-the-neonatal-icu-of-a-tertiary-care-hospital-in-bangladesh-a-retrospective-chart-review
#16
Sanjoy Kumer Dey, Sharmin Afroze, Tariqul Islam, Ismat Jahan, Mohammad Kamrul Hassan Shabuj, Suraiya Begum, Mohammod Jobayer Chisti, Mohammad Abdul Mannan, Mohammod Shahidullah
BACKGROUND: Expectant reduction of neonatal mortality and formulation of preventive strategies can only be achieved by analysis of risk factors in a particular setting. This study aimed to document incidence of neonatal death and to analyze the risk factors associated with neonatal death. METHODS: This retrospective study was carried out in department of Neonatology, Bangabandhu Sheikh Mujib Medical University (BSMMU) over a 12-month period from January to December 2015...
October 26, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29068106/clinical-profile-of-congenital-rubella-syndrome-in-yogyakarta-indonesia
#17
Elisabeth S Herini, Gunadi, Agung Triono, Fita Wirastuti, Kristy Iskandar, Niprida Mardin, Yati Soenarto
BACKGROUND: Congenital rubella syndrome (CRS) has many severe neurological manifestations and other systemic consequences in patients. Although various studies have been done in Indonesia, there have not been any conclusive results on CRS incidence. Therefore, we aimed to investigate the incidence, clinical manifestations and outcomes of CRS in Yogyakarta, Indonesia. METHODS: A descriptive study involving a review of congenital anomalies associated with CRS cases at Dr...
October 25, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/29066179/ethical-implications-of-the-use-of-decision-aids-for-antenatal-counseling-at-the-limits-of-gestational-viability
#18
REVIEW
Ursula Guillen, Haresh Kirpalani
Shared decision-making is a recent priority in neonatology. However, its implementation is at an early stage. Decision aids are tools designed to assist in shared decision-making. They help patients competently participate in making healthcare decisions. There are limited studies in neonatology on the formal use of decision aids as used in adult medicine. Decision aids are relatively new, even in adult medicine where they were pioneered; therefore, there is a lack of systematic oversight to their development and use...
October 21, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29053701/marshall-klaus-the-impact-of-a-pioneer-in-neonatology
#19
Avroy A Fanaroff, Richard J Martin
Pediatric Research accepted article preview online, 20 October 2017. doi:10.1038/pr.2017.269.
October 20, 2017: Pediatric Research
https://www.readbyqxmd.com/read/29042914/the-educational-challenge-of-paediatric-virology-an-interview-with-professor-of-neonatology-anne-greenough
#20
Ioannis N Mammas, Demetrios A Spandidos
According to Professor Anne Greenough, Professor of Neonatology and Clinical Respiratory Physiology at the King's College London (London, UK), Paediatric Virology is indeed a rapidly increasing educational challenge. Professor Greenough, who in 1992 wrote her book on congenital, perinatal and neonatal infections, believes that during the past 3 decades, paediatric health professionals are becoming increasingly involved in specialised care and follow-up of paediatric patients with viral diseases, who require advanced medical care and innovative technological services...
October 2017: Experimental and Therapeutic Medicine
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