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https://www.readbyqxmd.com/read/28807544/use-and-misuse-of-drugs-in-perinatology-and-neonatology
#1
EDITORIAL
Hany Aly
No abstract text is available yet for this article.
August 11, 2017: Seminars in Fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28807426/clinical-usefulness-of-catheter-drawn-blood-samples-and-catheter-tip-cultures-for-the-diagnosis-of-catheter-related-bloodstream-infections-in-neonatology-a-systematic-review
#2
REVIEW
Janita Ferreira, Paulo Augusto Moreira Camargos, Wanessa Trindade Clemente, Roberta Maia de Castro Romanelli
OBJECTIVES: Neonatal sepsis is the most frequent health care-associated infection in neonatal units. This study aimed to analyze articles on the clinical usefulness of catheter-drawn blood samples and catheter tip cultures for the diagnosis of intravascular catheter-related bloodstream infection (CRBSI) in neonates. METHODS: A systematic search was performed for studies published from 1987-2017, without language restriction. Observational studies carried out in neonates with CRBSI diagnosed using catheter-drawn blood samples or catheter tip cultures were included...
August 11, 2017: American Journal of Infection Control
https://www.readbyqxmd.com/read/28802343/using-statistical-process-control-to-drive-improvement-in-neonatal-care-a-practical-introduction-to-control-charts
#3
REVIEW
Munish Gupta, Heather C Kaplan
Quality improvement (QI) is based on measuring performance over time, and variation in data measured over time must be understood to guide change and make optimal improvements. Common cause variation is natural variation owing to factors inherent to any process; special cause variation is unnatural variation owing to external factors. Statistical process control methods, and particularly control charts, are robust tools for understanding data over time and identifying common and special cause variation. This review provides a practical introduction to the use of control charts in health care QI, with a focus on neonatology...
September 2017: Clinics in Perinatology
https://www.readbyqxmd.com/read/28802342/improving-value-in-neonatal-intensive-care
#4
REVIEW
Timmy Ho, John A F Zupancic, DeWayne M Pursley, Dmitry Dukhovny
Work within the US health care system has sought to improve outcomes, decrease costs, and improve the patient experience. Combining those three elements leads to value-added care. Quality improvement within neonatology has focused primarily on the improvement of clinical outcomes without explicit consideration of cost. Future improvement efforts in neonatology should consider opportunities to decrease or eliminate waste, and improve outcomes. Consideration of how a change affects all stakeholders reveals potential cost-saving opportunities, and developing aims with value in mind facilitates understanding and goal-setting with senior administrative leaders...
September 2017: Clinics in Perinatology
https://www.readbyqxmd.com/read/28802337/eliminating-undesirable-variation-in-neonatal-practice-balancing-standardization-and-customization
#5
REVIEW
Maya Balakrishnan, Aarti Raghavan, Gautham K Suresh
Consistency of care and elimination of unnecessary and harmful variation are underemphasized aspects of health care quality. This article describes the prevalence and patterns of practice variation in health care and neonatology; discusses the potential role of standardization as a solution to eliminating wasteful and harmful practice variation, particularly when it is founded on principles of evidence-based medicine; and proposes ways to balance standardization and customization of practice to ultimately improve the quality of neonatal care...
September 2017: Clinics in Perinatology
https://www.readbyqxmd.com/read/28791867/evolution-of-newborns-urinary-metabolomic-profiles-according-to-age-and-growth
#6
Aurélien Scalabre, Elodie Jobard, Delphine Demède, Ségolène Gaillard, Clément Pontoizeau, Pierre Mouriquand, Bénédicte Elena-Herrmann, Pierre-Yves Mure
Improving the management of neonatal diseases and prevention of chronic diseases in adulthood requires a better comprehension of the complex maturational processes associated with newborns development. Urine-based metabolomic studies play a promising role in the fields of pediatrics and neonatology, relying on simple and non-invasive collection procedures while integrating a variety of factors such as genotype, nutritional state, lifestyle and diseases. Here, we investigate the influence of age, weight, height and gender on the urine metabolome during the first 4 months of life...
August 9, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28777308/key-challenges-in-the-search-for-innovative-drug-treatments-for-special-populations-converging-needs-in-neonatology-pediatrics-and-medical-genetics
#7
Stuart MacLeod
The explosion of knowledge concerning the interplay of genetic and environmental factors determining pathophysiology and guiding therapeutic choice has altered the landscape in pediatric clinical pharmacology and pharmacy. The need for innovative research methods and design expertise for small clinical trials to be undertaken in sparse populations has been accentuated. At the same time, shortfalls in critical human resources represent a key challenge, especially in low- and middle-income countries where the need for new research and education directions is greatest...
August 4, 2017: Children
https://www.readbyqxmd.com/read/28774362/-intrauterine-growth-curves-for-body-weight-body-length-head-circumference-chest-circumference-and-crown-rump-length-in-16%C3%A2-887-neonates-with-a-gestational-age-of-27-42-weeks-in-shenzhen-china
#8
Xiao-Yun Huang, Hui-Long Liu, Min Lei, Hui-Fen Mai, Chao-Hui Lian, You-Cong Li
OBJECTIVE: To establish the intrauterine growth curves of neonates in Shenzhen, China and to investigate the intrauterine growth of neonates in Shenzhen. METHODS: Cross-sectional cluster sampling was performed for an on-the-spot investigation of 16 887 neonates (9 418 males and 7 469 females) with a gestational age of 27-42 weeks who were born in two hospitals in Shenzhen from April 2013 to September 2015. The Lambda Mu Sigma (LMS) method was used for the curve fitting of body weight, body length, head circumference, chest circumference, and crown-rump length...
August 2017: Zhongguo Dang Dai Er Ke za Zhi, Chinese Journal of Contemporary Pediatrics
https://www.readbyqxmd.com/read/28768127/-save-or-create-the-practical-asymmetry-of-judgment-training-in-decision-making-in-neonatology-when-basic-desires-clash-with-preparation-to-act
#9
Michael R Gomez
No abstract text is available yet for this article.
August 2017: American Journal of Bioethics: AJOB
https://www.readbyqxmd.com/read/28768121/dealing-with-moral-dilemmas-at-the-neonatology-ward-the-importance-of-joint-case-by-case-reflection
#10
Suzanne Metselaar, Machteld van Scherpenzeel, Guy Widdershoven
No abstract text is available yet for this article.
August 2017: American Journal of Bioethics: AJOB
https://www.readbyqxmd.com/read/28758538/-you-can-only-give-warmth-to-your-baby-when-it-s-too-late-parents-bonding-with-their-extremely-preterm-and-dying-child
#11
Andrea Abraham, Manya J Hendriks
This study on end-of-life decisions in extremely preterm babies shows that the parents under study experience a multitude of stressors due to the immediate separation after birth, the alienating setting of the neonatal intensive care unit (NICU), the physical distance to the child, medical uncertainties, and upcoming decisions. Even though they are considered to be parents (assigned parenthood), they cannot act as primary caregivers. Instead, they depend on professional instructions for access and care. Embodied parenthood can be experienced only at the end-of-life, that is, during the dying trajectory and after the child's death...
July 1, 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/28757329/infections-following-surgical-patent-ductus-arteriosus-ligation-in-vlbw-neonates
#12
Katarzyna Kopeć-Godlewska, Jadwiga Wójkowska-Mach
BACKGROUND: Very low birth weight (VLBW) neonates (<1,500 g) comprise approximately 1% of liveborn infants in Poland. Patent ductus arteriosus (PDA) is a common complication of prematurity. This study aimed to determine how many VLBW neonates treated in the participating units needed a surgical correction of PDA, and to evaluate the incidence of various types of post-operative infections, and their microbiology. METHODS: Observational study in five neonatology departments by the Polish Neonatology Surveillance Network, involving 2039 VLBW newborns of whom 103 (5...
July 27, 2017: Journal of Hospital Infection
https://www.readbyqxmd.com/read/28755799/-professional-practice-evaluation-of-injectable-drug-preparation-and-administration-in-neonatology
#13
P Morin, B Guillois, L Gloanec, N Chatelier, G Saint-Lorant
AIM: Adverse drug events are a daily concern in neonatology departments. The aim of this study was to assess the professional practices of preparation and administration of injectable forms of medications in neonatology. MATERIALS AND METHODS: A professional practice evaluation with regard to the preparation and administration of various injectable forms of medications in different neonatology units within a given department was conducted by a pharmacy intern based on an assessment grid comprising ten criteria...
July 26, 2017: Archives de Pédiatrie: Organe Officiel de la Sociéte Française de Pédiatrie
https://www.readbyqxmd.com/read/28752833/mapping-the-nursing-competences-in-neonatology-a-qualitative-research
#14
Emanuela Alfieri, Alessia Alebbi, M Giovanna Bedini, Laura Boni, Chiara Foà
BACKGROUND AND AIM: There are several studies that support the importance of advanced expertise and specialization of the neonatal pediatric nurse. However, proceeding with a analysis of the scientific literature regarding the nursing advanced competence in neonatology, very few studies specify and define these competences. The aim of the study is investigate and analyze skills, tasks and responsibilities of the neonatal pediatric nurse, to map a "neonatal nurse competence profile", offered from the points of view of the Neonatology Units professionals...
July 18, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28752179/-clinical-autopsies-in-switzerland-a-status-report
#15
REVIEW
A-K Rodewald, P Bode, G Cathomas, H Moch
BACKGROUND: The number of autopsies has been steadily declining worldwide over the past decades. The reasons for this are diverse. Legislation regarding opposition and consent rules does not appear to have had a significant impact on the autopsy rates. Above all, structural causes and the attitude of the medical profession are the reasons for this decline. The main argument for a high autopsy rate is the identification of diagnostic errors; however, diagnostic discrepancies are relatively independent of the rate of autopsies performed...
July 27, 2017: Der Pathologe
https://www.readbyqxmd.com/read/28748430/inicu-integrated-neonatal-care-unit-capturing-neonatal-journey-in-an-intelligent-data-way
#16
Harpreet Singh, Gautam Yadav, Raghuram Mallaiah, Preetha Joshi, Vinay Joshi, Ravneet Kaur, Suneyna Bansal, Samir K Brahmachari
Neonatal period represents first 28 days of life, which is the most vulnerable time for a child's survival especially for the preterm babies. High neonatal mortality is a prominent and persistent problem across the globe. Non-availability of trained staff and infrastructure are the major recognized hurdles in the quality care of these neonates. Hourly progress growth charts and reports are still maintained manually by nurses along with continuous calculation of drug dosage and nutrition as per the changing weight of the baby...
August 2017: Journal of Medical Systems
https://www.readbyqxmd.com/read/28736678/rapid-assessment-zika-virus-knowledge-among-clinical-specialists-in-singapore-a-cross-sectional-survey
#17
Chee F Yung, Clarence C Tam, Victor S Rajadurai, Jerry Ky Chan, Mabel Sf Low, Yong H Ng, Koh C Thoon, Lay K Tan
INTRODUCTION: We report the results of a rapid assessment of Zika virus awareness among key clinical specialties in Singapore. METHODS: Between June 6 and June 19, 2016 we conducted an online survey of doctors working in obstetrics and gynaecology, neonatology and paediatrics in Singapore. The survey included 15 multiple choice questions to measure respondents' knowledge of Zika virus in four domains covering clinical and public health. RESULTS: A total of 110 survey responses (15% response rate) were obtained, 82% of respondents worked in the public sector...
May 3, 2017: PLoS Currents
https://www.readbyqxmd.com/read/28728204/how-do-obstetric-and-neonatology-teams-communicate-prior-to-high-risk-deliveries
#18
Nathan C Sundgren, Gautham K Suresh
No abstract text is available yet for this article.
July 20, 2017: American Journal of Perinatology
https://www.readbyqxmd.com/read/28715154/the-role-of-oxidative-stress-in-acute-renal-injury-of-newborn-rats-exposed-to-hypoxia-and-endotoxin
#19
Egor Y Plotnikov, Tatiana A Pavlenko, Irina B Pevzner, Ljubava D Zorova, Vasily N Manskikh, Denis N Silachev, Gennady T Sukhikh, Dmitry B Zorov
Neonatal kidney injury is a frequent pathology, especially among premature infants. The search for effective nephroprotection requires the creation of adequate experimental models of nephropathy in newborns. In this study, we explored the development of acute kidney injury (AKI) in neonatal rats during hypoxia or administration of endotoxin. We found that 2-h hypoxia (8% O2 ) and the intraperitoneal injection of 4 mg/kg lipopolysaccharide (LPS) causes the appearance of AKI markers, such as КIM-1 and NGAL in the rat urine after 24 and 72 h of exposure...
July 17, 2017: FEBS Journal
https://www.readbyqxmd.com/read/28709844/-transfusion-and-its-specific-problems-in-pediatrics-and-neonatology
#20
Y Pérel, C Runel, Y Huguenin, L Renesme, N Aladjidi
Principles of transfusion strategy have been used for neonates and children similar to adults. However, due to substantial discrepancies between physiology/pathology in children and in their adult counterparts, decisions, indications, and doses are different from those of adults, especially in neonates. Specific data and practice guidelines for blood product transfusion are reported owing to the experience of pediatrics and neonatology units and partners of the French Blood product bank.
July 11, 2017: Transfusion Clinique et Biologique: Journal de la Société Française de Transfusion Sanguine
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