keyword
https://read.qxmd.com/read/37347686/the-nih-pediatric-young-adult-chordoma-clinic-and-natural-history-study-making-advances-in-a-very-rare-tumor
#21
JOURNAL ARTICLE
Liny John, Hannah Smith, Maran Ilanchezhian, Robin Lockridge, Karlyne M Reilly, Margarita Raygada, Eva Dombi, Abby Sandler, Barbara J Thomas, John Glod, Markku Miettinen, Taryn Allen, Josh Sommer, Joan Levy, Shannon Lozinsky, David Dix, Eric Bouffet, Shannon MacDonald, Debraj Mukherjee, Carl H Snyderman, Nicholas R Rowan, Robert Malyapa, Deric M Park, Christopher Heery, Paul A Gardner, Gregory M Cote, Sarah Fuller, John A Butman, Sadhana Jackson, James L Gulley, Brigitte C Widemann, Mary Frances Wedekind
BACKGROUND: Chordomas are rare tumors arising from the skull base and spine, with approximately 20 pediatric chordoma cases in the Unitedn States per year. The natural history and optimal treatment of pediatric chordomas, especially poorly differentiated and dedifferentiated subtypes, is incompletely understood. Herein, we present findings from our first National Cancer Institute (NCI) chordoma clinic and a retrospective analysis of published cases of pediatric poorly differentiated chordomas (PDC) and dedifferentiated chordomas (DC)...
June 22, 2023: Pediatric Blood & Cancer
https://read.qxmd.com/read/37345354/nci-intramural-program-approach-to-rare-tumors-natural-history-study-of-rare-solid-tumors-in-children-and-adults-a-longitudinal-comprehensive-data-and-biospecimen-collection-protocol
#22
JOURNAL ARTICLE
Mary Frances Wedekind, Karlyne M Reilly, Jaydira Del Rivero, Robin Lockridge, Taryn Allen, Margarita Raygada, Donna Bernstein, Barbara J Thomas, Christina Vivelo, Jason Levine, Nurlan Shonkoev, Kenneth Aldape, John Glod, Abby B Sandler, Brigitte C Widemann
Rare tumors across the world are lacking adequate knowledge, resources, and community. Through partnership with patients, advocacy organizations, researchers, and clinicians, we have developed a comprehensive, longitudinal, prospective, and retrospective natural history protocol to collect, analyze, and share data on patients with rare tumors. A strong collaborative effort is vital to ensure success of enrollment, patient engagement, data collection, and analysis to ultimately develop clinical trials to improve outcomes for patients with rare cancers...
June 21, 2023: Pediatric Blood & Cancer
https://read.qxmd.com/read/37340101/interaction-of-hydrocortisone-and-illness-severity-on-head-growth-in-cohort-of-elbw-infants
#23
JOURNAL ARTICLE
Haiwen Chen, Khyzer B Aziz, Harisa Spahic, Sarah Miller, Melike Guryildirim, Austin Sellers, Sandra Brooks, Alison Kilborn, Allen D Everett, Frances J Northington, Carl E Stafstrom, Raul Chavez-Valdez
BACKGROUND: Extremely low birth weight (ELBW) infants comprise a fragile population at risk for neurodevelopmental disabilities (NDD). Systemic steroids were previously associated with NDD, but more recent studies suggest hydrocortisone (HCT) may improve survival without increasing NDD. However, the effects of HCT on head growth adjusted for illness severity during NICU hospitalization are unknown. Thus, we hypothesize that HCT will protect head growth, accounting for illness severity using a modified neonatal Sequential Organ Failure Assessment (M-nSOFA) score...
June 20, 2023: Pediatric Research
https://read.qxmd.com/read/37325190/scalable-modular-continuous-wave-functional-near-infrared-spectroscopy-system-spotlight
#24
JOURNAL ARTICLE
Daniel Anaya, Gautam Batra, Peter Bracewell, Ryan Catoen, Dev Chakraborty, Mark Chevillet, Pradeep Damodara, Alvin Dominguez, Laurence Emms, Zifan Jiang, Ealgoo Kim, Keith Klumb, Frances Lau, Rosemary Le, Jamie Li, Brett Mateo, Laura Matloff, Asha Mehta, Emily M Mugler, Akansh Murthy, Sho Nakagome, Ryan Orendorff, E-Fann Saung, Roland Schwarz, Ruben Sethi, Rudy Sevile, Ajay Srivastava, John Sundberg, Ying Yang, Allen Yin
SIGNIFICANCE: We present a fiberless, portable, and modular continuous wave-functional near-infrared spectroscopy system, Spotlight, consisting of multiple palm-sized modules-each containing high-density light-emitting diode and silicon photomultiplier detector arrays embedded in a flexible membrane that facilitates optode coupling to scalp curvature. AIM: Spotlight's goal is to be a more portable, accessible, and powerful functional near-infrared spectroscopy (fNIRS) device for neuroscience and brain-computer interface (BCI) applications...
June 2023: Journal of Biomedical Optics
https://read.qxmd.com/read/37231858/quantification-of-diffusion-mri-for-prognostic-prediction-of-neonatal-hypoxic-ischemic-encephalopathy
#25
REVIEW
Kengo Onda, Raul Chavez-Valdez, Ernest M Graham, Allen D Everett, Frances J Northington, Kenichi Oishi
Neonatal-hypoxic ischemic encephalopathy (HIE) is the leading cause of acquired neonatal brain injury with the risk of developing serious neurologic sequelae and death. An accurate and robust prediction of short- and long-term outcomes may provide clinicians and families with fundamental evidence for their decision-making, the design of treatment strategies, and the discussion of developmental intervention plans after discharge. Diffusion tensor imaging (DTI) is one of the most powerful neuroimaging tools with which to predict the prognosis of neonatal HIE by providing microscopic features that cannot be assessed by conventional MRI...
May 10, 2023: Developmental Neuroscience
https://read.qxmd.com/read/37195562/correction-a-role-for-macrophages-under-cytokine-control-in-mediating-resistance-to-adi-peg20-pegargiminase-in-ass1-deficient-mesothelioma
#26
Melissa M Phillips, Iuliia Pavlyk, Michael Allen, Essam Ghazaly, Rosalind Cutts, Josephine Carpentier, Joe Scott Berry, Callum Nattress, Shenghui Feng, Gunnel Hallden, Claude Chelala, John Bomalaski, Jeremy Steele, Michael Sheaff, Frances Balkwill, Peter W Szlosarek
No abstract text is available yet for this article.
May 17, 2023: Pharmacological Reports: PR
https://read.qxmd.com/read/37146730/racial-differences-in-covid-19-severity-associated-with-history-of-substance-use-disorders-and-overdose-findings-from-multi-site-electronic-health-records-in-new-york-city
#27
JOURNAL ARTICLE
Bennett Allen, Cale Basaraba, Thomas Corbeil, Bianca Rivera, Frances R Levin, Diana M Martinez, Katharina Schultebraucks, Brandy F Henry, Harold A Pincus, Caroline Arout, Noa Krawczyk
Substance use disorders (SUD) are associated with increased risk of worse COVID-19 outcomes. Likewise, racial/ethnic minority patients experience greater risk of severe COVID-19 disease compared to white patients. Providers should understand the role of race and ethnicity as an effect modifier on COVID-19 severity among individuals with SUD. This retrospective cohort study assessed patient race/ethnicity as an effect modifier of the risk of severe COVID-19 disease among patients with histories of SUD and overdose...
May 3, 2023: Preventive Medicine
https://read.qxmd.com/read/37069343/the-impact-of-preexisting-psychiatric-disorders-and-antidepressant-use-on-covid-19-related-outcomes-a-multicenter-study
#28
JOURNAL ARTICLE
Katharina Schultebraucks, Wivine Blekic, Cale Basaraba, Tom Corbeil, Zain Khan, Brandy F Henry, Noa Krawczyk, Bianca D Rivera, Bennett Allen, Caroline Arout, Harold Alan Pincus, Diana M Martinez, Frances R Levin
Pre-existing mental disorders are linked to COVID-19-related outcomes. However, the findings are inconsistent and a thorough analysis of a broader spectrum of outcomes such as COVID-19 infection severity, morbidity, and mortality is required. We investigated whether the presence of psychiatric diagnoses and/or the use of antidepressants influenced the severity of the outcome of COVID-19. This retrospective cohort study evaluated electronic health records from the INSIGHT Clinical Research Network in 116,498 individuals who were diagnosed with COVID-19 between March 1, 2020, and February 23, 2021...
April 17, 2023: Molecular Psychiatry
https://read.qxmd.com/read/37023833/preoperative-code-status-discussion-workflows-targets-for-improvement-in-multidisciplinary-pathways
#29
JOURNAL ARTICLE
Sashini Godage, Katie Rowe, Frances Y Hu, Angela M Bader, Zara Cooper, Rachelle E Bernacki, David L Hepner, Matthew B Allen
CONTEXT: Discussion of perioperative code status is an important element of preoperative care and a component of the American College of Surgeons' Geriatric Surgery Verification (GSV) program. Evidence suggests code status discussions (CSDs) are not routinely performed and are inconsistently documented. OBJECTIVES: Because preoperative decision making is a complex process spanning multiple providers, this study aims to utilize process mapping to highlight challenges associated with CSDs and inform efforts to improve workflows and implement elements of the GSV program...
July 2023: Journal of Pain and Symptom Management
https://read.qxmd.com/read/37010783/a-role-for-macrophages-under-cytokine-control-in-mediating-resistance-to-adi-peg20-pegargiminase-in-ass1-deficient-mesothelioma
#30
JOURNAL ARTICLE
Melissa M Phillips, Iuliia Pavlyk, Michael Allen, Essam Ghazaly, Rosalind Cutts, Josephine Carpentier, Joe Scott Berry, Callum Nattress, Shenghui Feng, Gunnel Hallden, Claude Chelala, John Bomalaski, Jeremy Steele, Michael Sheaff, Frances Balkwill, Peter W Szlosarek
BACKGROUND: Pegylated arginine deiminase (ADI-PEG20; pegargiminase) depletes arginine and improves survival outcomes for patients with argininosuccinate synthetase 1 (ASS1)-deficient malignant pleural mesothelioma (MPM). Optimisation of ADI-PEG20-based therapy will require a deeper understanding of resistance mechanisms, including those mediated by the tumor microenvironment. Here, we sought to reverse translate increased tumoral macrophage infiltration in patients with ASS1-deficient MPM relapsing on pegargiminase therapy...
April 3, 2023: Pharmacological Reports: PR
https://read.qxmd.com/read/36909473/whole-genome-sequencing-of-borrelia-burgdorferi-isolates-reveals-linked-clusters-of-plasmid-borne-accessory-genome-elements-associated-with-virulence
#31
Jacob E Lemieux, Weihua Huang, Nathan Hill, Tjasa Cerar, Lisa Freimark, Sergio Hernandez, Matteo Luban, Vera Maraspin, Petra Bogovic, Katarina Ogrinc, Eva Ruzic-Sabljic, Pascal Lapierre, Erica Lasek-Nesselquist, Navjot Singh, Radha Iyer, Dionysios Liveris, Kurt D Reed, John M Leong, John A Branda, Allen C Steere, Gary P Wormser, Franc Strle, Pardis C Sabeti, Ira Schwartz, Klemen Strle
Lyme disease is the most common vector-borne disease in North America and Europe. The clinical manifestations of Lyme disease vary based on the genospecies of the infecting Borrelia burgdorferi spirochete, but the microbial genetic elements underlying these associations are not known. Here, we report the whole genome sequence (WGS) and analysis of 299 patient-derived B. burgdorferi sensu stricto ( Bbss ) isolates from patients in the Eastern and Midwestern US and Central Europe. We develop a WGS-based classification of Bbss isolates, confirm and extend the findings of previous single- and multi-locus typing systems, define the plasmid profiles of human-infectious Bbss isolates, annotate the core and strain-variable surface lipoproteome, and identify loci associated with disseminated infection...
February 27, 2023: bioRxiv
https://read.qxmd.com/read/36814302/protocol-for-a-pilot-randomised-controlled-trial-to-evaluate-integrated-support-from-pharmacist-independent-prescriber-and-third-sector-worker-for-people-experiencing-homelessness-the-phoenix-community-pharmacy-study
#32
JOURNAL ARTICLE
Vibhu Paudyal, Richard Lowrie, Frances S Mair, Lee Middleton, Versha Cheed, Jennifer Hislop, Andrea Williamson, Nigel Barnes, Catherine Jolly, Karen Saunders, Natalie Allen, Parbir Jagpal, George Provan, Steven Ross, Carole Hunter, Sarah Tearne, Andrew McPherson, Helena Heath, Cian Lombard, Adnan Araf, Emily Dixon, Amy Hatch, Jane Moir, Shabana Akhtar
BACKGROUND: People experiencing homelessness (PEH) have complex health and social care needs and most die in their early 40 s. PEH frequently use community pharmacies; however, evaluation of the delivery of structured, integrated, holistic health and social care intervention has not been previously undertaken in community pharmacies for PEH. PHOENIx (Pharmacy Homeless Outreach Engagement Non-medical Independent prescribing Rx) has been delivered and tested in Glasgow, Scotland, by NHS pharmacist independent prescribers and third sector homelessness support workers offering health and social care intervention in low threshold homeless drop-in venues, emergency accommodation and emergency departments, to PEH...
February 23, 2023: Pilot and Feasibility Studies
https://read.qxmd.com/read/36563252/probing-the-critical-nucleus-size-in-the-metal-insulator-phase-transition-of-vo_-2
#33
JOURNAL ARTICLE
Lei Jin, Yin Shi, Frances I Allen, Long-Qing Chen, Junqiao Wu
In a first-order phase transition, critical nucleus size governs nucleation kinetics, but the direct experimental test of the theory and determination of the critical nucleation size have been achieved only recently in the case of ice formation in supercooled water. The widely known metal-insulator phase transition (MIT) in strongly correlated VO_{2} is a first-order electronic phase transition coupled with a solid-solid structural transformation. It is unclear whether classical nucleation theory applies in such a complex case...
December 9, 2022: Physical Review Letters
https://read.qxmd.com/read/36522270/obituary-univ-professor-dr-gerold-stanek-1946-2022
#34
JOURNAL ARTICLE
Jeremy S Gray, Olaf Kahl, Wolfgang Kristoferitsch, Allen Steere, Franc Strle, Jochen Süss, Gary P Wormser
No abstract text is available yet for this article.
December 13, 2022: Ticks and Tick-borne Diseases
https://read.qxmd.com/read/36469088/a-realist-evaluation-of-a-multifactorial-falls-prevention-programme-in-care-homes
#35
JOURNAL ARTICLE
Paul A Leighton, Janet Darby, Frances Allen, Marie Cook, Rachel Evley, Chris Fox, Maureen Godfrey, Adam Gordon, John Gladman, Jane Horne, Kate Robertson, Pip Logan
BACKGROUND: falls in care homes are common, costly and hard to prevent.Multifactorial falls programmes demonstrate clinical and cost-effectiveness, but the heterogeneity of the care home sector is a barrier to their implementation. A fuller appreciation of the relationship between care home context and falls programme delivery will guide development and support implementation. METHODS: this is a multi-method process evaluation informed by a realist approach.Data include fidelity observations, stakeholder interviews, focus groups, documentary review and falls-rate data...
December 5, 2022: Age and Ageing
https://read.qxmd.com/read/36459420/covid-19-complications-among-patients-with-opioid-use-disorder-a-retrospective-cohort-study-across-five-major-nyc-hospital-systems
#36
JOURNAL ARTICLE
Noa Krawczyk, Bianca D Rivera, Cale Basaraba, Thomas Corbeil, Bennett Allen, Katharina Schultebraucks, Brandy F Henry, Harold A Pincus, Frances R Levin, Diana Martinez
BACKGROUND AND AIMS: Individuals with opioid use disorder (OUD) suffer disproportionately from COVID-19. To inform clinical management of OUD patients, research is needed to identify characteristics associated with COVID-19 progression and death among this population. We aimed to investigate the role of OUD and specific comorbidities on COVID-19 progression among hospitalized OUD patients. DESIGN: Retrospective cohort study of merged electronic health records (EHR) from five large private health systems SETTING: New York City, New York, USA, 2011-2021 PARTICIPANTS: Adults with a COVID-19 encounter and OUD or opioid overdose diagnosis between March 2020-February 2021 MEASUREMENTS: Primary exposure included diagnosis of OUD/opioid overdose...
December 2, 2022: Addiction
https://read.qxmd.com/read/36450401/2022-canadian-surgery-forum-sept-15-17-2022-abstracts-presented-at-the-2022-canadian-surgery-forum-in-toronto-ontario
#37
JOURNAL ARTICLE
Yasser Selim, Élise Di Lena, Nadia Safa, Sid Rahman, Pepa Kaneva, Liane Feldman, Nawaf Abu-Omar, Zarrukh Baig, Nathan Ginther, Dilip Gill, Zarrukh Baig, Zaini Sarwar, Carlos Verdiales, Mike Moser, Kevin Verhoeff, Valentin Mocanu, Breanna Fang, Jerry Dang, Warren Sun, Noah Switzer, Daniel Birch, Shahzeer Karmali, Julie La, Anood Alqaydi, Xuejiao Wei, Genevieve Digby, Susan Brogly, Shaila Merchant, Kieran Purich, Kevin Verhoeff, Alexander Miles, Janice Y Kung, A M James Shapiro, David L Bigam, Samantha Albacete, Ashlee Matkin, Danielle Dumestre, Lashan Peiris, Rahim Valji, Simon Turner, Kieran Purich, Kevin Verhoeff, Brett Mador, Steffane McLennan, Ali Safar, Atif Jastaniah, Morgan Schellenberg, Natthida Owattanapanich, Areg Grigorian, Lydia Lam, Jeffry Nahmias, Kenji Inaba, Morgan Schellenberg, Panagiotis Liasidis, Kenji Inaba, Demetrios Demetriades, Morgan Schellenberg, Elizabeth R Benjamin, Shaun Cowan, Natthida Owattanapanich, Monica D Wong, Kenji Inaba, Demetrios Demetriades, Morgan Schellenberg, Natthida Owattanapanich, Brent Emigh, Lindsey Karavites, Damon H Clark, Lydia Lam, Kenji Inaba, Morgan Schellenberg, Elizabeth R Benjamin, Natthida Owattanapanich, Kenji Inaba, Demetrios Demetriades, Morgan Schellenberg, Geoffrey A Anderson, Natthida Owattanapanich, Vincent Cheng, Lydia Lam, Kenji Inaba, Lee Myers, Julian Daza, Brian Cuthbertson, Paul Myles, Mark Shulman, Duminda Wijeysundera, Lyndsay T Glass, Patrick B Murphy, Laura Allen, Kathryn Minkhorst, Dillon Bowker, Ephraim S Tang, Kenneth Leslie, Jeffrey E Hawel, Kevin Verhoeff, Odelle Ma, Kieran Purich, Samuel Skinner, Raveena Dhaliwal, Matt Strickland, Garrett Johnson, Jason Park, Ashley Vergis, Lawrence Gillman, Justin Rivard, Keegan Guidolin, Justin Lin, Anudari Zorigtbaatar, Minahil Nadeem, Tarek Ibrahim, Zdenka Neilson, Kyung Young Peter Kim, Luckshi Rajendran, Sami Chadi, Fayez Quereshy, Lyndsay T Glass, Malcolm Davidson, Emily Friedrich, Caitlin Champion, Saba Balvardi, Koorosh Semsar-Kazerooni, Pepa Kaneva, Carmen Mueller, Melina Vassiliou, Mohammed Al Mahroos, Julio Fiore, Kevin Schwartzman, Liane Feldman, Nada Gawad, Kieran Purich, Kevin Verhoeff, Blaire Anderson, Tyler McKechnie, Ryan Daniel, Colin Kruse, Marc Levin, Yung Lee, Aristithes Doumouras, Dennis Hong, Cagla Eskicioglu, Tyler McKechnie, Christopher Povolo, Jay Lee, Yung Lee, Lily Park, Aristithes Doumouras, Dennis Hong, Mohit Bhandari, Cagla Eskicioglu, Kieran Purich, Esther Lee, Kevin Verhoeff, Dasan Sydora, Simon Turner, Matt Strickland, Jessica Henley, Darrell Boone, Stephanie Roberts, Emma Imbert, Duncan McGrouther, Paul Manuel, Christine Li, Mark Dykstra, Haili Wang, Ryan Snelgrove, Samuel Skinner, Kevin Verhoeff, Kieran Purich, Troy Perry, Matthew Strickland, Raveena Dhaliwal, Tori Lenet, Stephanie Skanes, Joseph Tropiano, Daniel McIsaac, Alan Tinmouth, Julie Hallet, Stuart Nicholls, Dean Fergusson, Guillaume Martel, Tori Lenet, Joseph Tropiano, Stephanie Skanes, Victoria Ivankovic, Daniel McIsaac, Alan Tinmouth, Andrea Patey, Dean Fergusson, Guillaume Martel, Jeff Metz, Reza Naqvi, Ruediger Noppens, Jeff Hawel, Ahmad Elnahas, Christopher Schlachta, Nawar Alkhamesi, Hilalion San Ahn, Tori Lenet, Richard Gilbert, Ranjeeta Mallick, Julie Shaw, Daniel McIsaac, Guillaume Martel, Uyen Do, Makena Pook, Tahereh Najafi, Fateme Rajabiyazdi, Charbel El-Kefraoui, Saba Balvardi, Natasha Barone, Hiba Elhaj, Philip Nguyen-Powanda, Lawrence Lee, Gabriele Baldini, Liane Feldman, Julio Fiore, Armin Rouhi, Kieran Purich, Uzair Jogiat, Deng Mapiour, Michael Kim, Brianna Greenberg, Ashlie Nadler, Hala Muaddi, Theres Stukel, Charles De Mestral, Avery Nathens, Stephen Pautler, Bobby Shayegan, Wael Hanna, Christopher Schlachta, Rodney Breau, Laura Hopkins, Timothy Jackson, Paul Karanicolas, Lily Park, Christopher Griffiths, Sam Ali, Victoria Archer, Zacharie Cloutier, Dexter Choi, Tyler McKechnie, Pablo Serrano, Kelly Vogt, J Andrew McClure, Philip Jones, Marko Mrkobrada, Suzanne Flier, Blayne Welk, Luc Dubois, Nori Bradley, Kosar Khwaja, Laura Allen, Lily Tung, Morad Hameed, Karina Spoyalo, Jacinthe Lampron, Carlos Garcia-Ochoa, Atif Jastaniah, Paul Engels, Gaurav Talwar, Zacharie Cloutier, Sam Minor, Brad Moffat, Neil Parry, Kelly Vogt, Shirley Xiaoxuan Deng, Tega Ebeye, Bree T Sharma, Anas Samman, Amna Zulfiqar, Roderick H Purzner, Brittany Greene, Melanie Tsang, Shiva Jayaraman, Patrick Murphy, Laura Allen, Chad G Ball, Morad Hameed, Paul Engels, Rahima Nenshi, Sandy Widder, Sam Minor, Neil Parry, Nori Bradley, Brad Moffat, Kelly Vogt, Mostafa Alhabboubi, Sender Liberman, Evan Wong, Talat Chughtai, Joel Turner, Jessica Lie, Sam Wiseman, Jennifer Li, Nicole Mak, Simon Laplante, Babak Namazi, Parmiss Kiani, Daniel Hashimoto, Adnan Alseidi, Mauricio Pasten, L Michael Brunt, Sujata Gill, Brian Davis, Matthew Bloom, Luise Pernar, Allan Okrainec, Amin Madani, Jessica Lie, Trevor Hamilton, Kylie Nabata, Jenny W Zhang, Darren Zhao, Phil Dawe, Morad Hameed, Jeremy Drung, Laura Allen, Ken Leslie, Jeremy Drung, Thomas Nixon, Kieran Purich, Kevin Verhoeff, Samuel Skinner, Raveena Dhaliwal, Matt Strickland, Alexandra Allard-Coutu, Barbara Heller, Victoria Wright, Wanjae Cho, Michael Wong, Kevin Singh, Sarah Mansouri, Émilie Comeau, Yves Collin, Sonia Cheng Oviedo, Alex Lee, Luckshi Rajendran, Tyler Lamb, Morgann Reid, Anastasia Turner, Kimberly Bertens, Janelle Rekman, Fady Balaa, Jillian Tweedy, Katerina Neumann, Geoff Porter, Michael A D'Elia, Iris Teo, Catherine L Forse, Reilly Musselman, Brent Hopkins, Lily Grozman, Nawaf Alshawan, Shannon Fraser, Simon Bergman, Jean-Sebastien Pelletier, Tsafrir Vanounou, Evan G Wong, Ananya Srivastava, Brodie Nolan, Lyon Qiao, James Jung, Kameela Alibhai, Isabelle Raîche, Heather McDonald, Nada Gawad, Christina Lee, Rona Cheifetz, Philippa Hawley, Jeongyoon Jenny Moon, Zachary Rehany, Mehrshad Bakhshi, Tarek Razek, Jeremy Grushka, Nathalie Boulanger, Larry Watt, Alexandra Vivier, Greg Clark, Paola Fata, Dan Deckelbaum, Kosar Khwaja, Atif Jastaniah, Evan Wong, Nathan How, Kevin Ren, Yuan Qiu, Karyssa Hamann, Karina Spoyalo, Annie Lalande, Andrea MacNeill, Jason Park, Annie Lalande, Stephanie Alexis, Karina Spoyalo, Keiko Patterson, Neha Gadhari, Jiaying Zhao, Andrea MacNeill, Zarrukh Baig, Rubia Ahmed, Ameer Farooq, Ahmer Karimuddin, Christina Schweitzer, Sam Wiseman, Joshua Keogh, Allison Chhor, Housne Begum, Noori Akhtar-Danesh, Christian Finley, Bright Huo, Daria Manos, Zhaolin Xu, Kara Matheson, Samuel Chun, John Fris, Alison Wallace, Daniel French, Yogita S Patel, Jean-Marc Baste, Yaron Shargall, Thomas K Waddell, Kazuhiro Yasufuku, Tiago N Machuca, Feng Xie, Lehana Thabane, Wael C Hanna, Yogita S Patel, Marla K Beauchamp, Joshua Wald, Lawrence Mbuagbaw, Brenda L Key, Sheryl M Green, Wael C Hanna, Uzair Jogiat, Abdollah Behzadi, Laura Donahoe, Awrad Nasralla, Julius Poon, Najib Safieddine, Nazgol Seyednejad, Iran Tavakoli, Simon Turner, Anna L McGuire, Sohat Sharma, Roy A Hilzenrat, Melissa McConechy, Ingrid Frank, Curtis Hughsman, Stephen Yip, James J Choi, John Yee, Uzair Jogiat, Hannah Sasewich, Simon Turner, Vickie Baracos, Dean Eurich, Heather Filafilo, Eric Bedard, Yung Lee, Yasith Samarasinghe, Janhavi Patel, Adree Khondker, Tyler McKechnie, Nadeesha Samarasinghe, Christian Finley, Wael Hanna, Yaron Shargall, John Agzarian, Evan Barber, Melissa Whidden, Francisco Aguirre, Andrew Graham, Gileh-Gol Akhtar-Danesh, Allison Chhor, Housne Begum, Joycelyne Ewusie, Lawrence Mbuagbaw, Shargall Yaron, Adom Bondzi-Simpson, Melanie Keshishi, Yonas Ademe, Ayalew Tizazu, Marci Rose, Sameena Uddin, Michael Ko, Riley Bowker, Jimmy Ddamba, Daniel French, Alison Wallace, Negar Ahmadi, Najib Safieddine, Sayf Gazala, Carmine Simone, Sami A Abdul, Frances Wright, Christian Finley, Patrick J Villeneuve, Sebastian Gilbert, Sudhir Sundaresan, Andrew J E Seely, Donna E Maziak, Pooja Patel, Daria Manos, Alison Wallace, Madelaine Plourde, Lyndsay Harrison, Donna Turner, Jolie Ringash, Douglas Manuel, Biniam Kidane, Vaibhav Gupta, Kathleen Decker, Laura Davis, Gail Darling, Carolyn Compton, Natalie Coburn, Randy Boyes, Michael Pugliese, Alyson Mahar, Amy Hsu, Ge Shi, Andrew Kokavec, Edward Ho, Ryan Waterman, Edward Wang, Kiera Harnden, Richard Malthaner, Rahul Nayak, Mehdi Qiabi, Ge Shi, Richard Malthaner, Rahul Nayak, Mehdi Qiabi, Jacob A Alaichi, Yogita Patel, Forough Farrokhyar, Marko Simunovic, Wael C Hanna, Biniam Kidane, Stephen Gowing, Richard Liu, Sadeesh Srinathan, Larry Tan, Linda Chang Qu, Richard Malthaner, Jacob Alaichi, Peter Malik, Yogita Patel, Wael Hanna, Emily Mackay, Umeed Fahim, Ajmal Hafizi, Ahmad S Ashrafi, Jay Lee, Tyler McKechnie, Nalin Amin, Aristithes Doumouras, Dennis Hong, Cagla Eskicioglu, Kieran Purich, Courtney Streu, Clarence Wong, Dan Schiller, Matthew Castelo, Colin Sue-Chue-Lam, Lawrence Paszat, Adena Scheer, Bettina Hansen, Teruko Kishibe, Nancy Baxter, Antonio Caycedo-Marulanda, Emma Neary, Tarek Ibrahim, Chris Verschoor, Sunil Patel, Shaila Merchant, Sami Chadi, Luis Romagnolo, Antonio Caycedo-Marulanda, Chris Verschoor, Carl Brown, Ahmer Karimuddin, Manoj Raval, Terry Phang, Elena Vikis, George Melich, Sunil Patel, Kelly Brennan, Sunil Patel, Antonio Caycedo-Marulanda, Shaila Merchant, Christopher Booth, Weidong Kong, Chad McClintock, Clare Bankhead, Carl Heneghan, Kelly Brennan, Sunil Patel, Chad McClintock, Shaila Merchant, Antonio Caycedo-Marulanda, Christopher Booth, Clare Bankhead, Carl Heneghan, Kelly Brennan, Lisa Zhang, Jennifer Flemming, Maya Djerboua, Sulaiman Nanji, Antonio Caycedo-Marulanda, Shaila Merchant, Sunil Patel, Richard Garfinkle, Marie Demian, Sarah Sabboobeh, Jeongyoon Moon, Michael Hulme-Moir, A Sender Liberman, Stan Feinberg, Dana M Hayden, Sami A Chadi, Sebastian Demyttenaere, Louise Samuel, Nevart Hotakorzian, Laurence Quintin, Nancy Morin, Gabriela Ghitulescu, Julio Faria, Carol-Ann Vasilevsky, Marylise Boutros, Sahil Sharma, Tyler Mckechnie, Jigish Khamar, Simarpreet Ichhpuniani, Cagla Eskicioglu, Sydney Candy, Sunil Patel, Shaila Merchant, Antonio Caycedo-Marulanda, Clare Bankhead, Carl Heneghan, Tyler McKechnie, Shaylan Govind, Jay Lee, Yung Lee, Dennis Hong, Cagla Eskicioglu, Tyler McKechnie, Justin Lu, Jigish Khamar, Yung Lee, Nalin Amin, Dennis Hong, Cagla Eskicioglu, Tyler McKechnie, Luisa Cardenas, Daniel Schep, Aristithes Doumouras, Dennis Hong, Raimond Wong, Oren Levine, Cagla Eskicioglu, Lawrence Lee, Carmen Mueller, Barry Stein, Patrick Charlebois, Sender Liberman, Gerald Fried, Liane Feldman, Stephan Robitaille, Anna Wang, Sender Liberman, Patrick Charlebois, Barry Stein, Julio F Fiore, Liane Feldman, Lawrence Lee, Stephan Robitaille, Anna Wang, Sender Liberman, Patrick Charlebois, Barry Stein, Julio F Fiore, Liane Feldman, Lawrence Lee, Hamid Sadri, Alan Barkun, Sydney Selznick, Jordan Levy, Ruxandra Bogdan, Jeffrey Hawel, Ahmad Elnahas, Nawar A Alkhamesi, Christopher M Schlachta, Vanessa Wiseman, Antonio Caycedo-Marulanda, Natasha Iaboni, David Hurlbut, Martin Kaufmann, Kevin Yi Mi Ren, Amoon Jamzad, Parvin Mousavi, Gabor Fichtinger, Christopher J B Nicol, John F Rudan, Vanessa Wiseman, Kelly Brennan, Antonio Caycedo-Marulanda, Shaila Merchant, Chad McClintock, Sunil V Patel, Vanessa Wiseman, Chad McClintock, Clare Bankhead, Shaila Merchant, Antonio Caycedo-Marulanda, Chris Booth, Carl Heneghan, Kelly Brennan, Lisa Zhang, Bright Huo, Alexandra Donaldson, Jennifer Flemming, Sulaiman Nanji, Antonio Caycedo-Marulanda, Shaila Merchant, Susan Brogly, Sunil Patel, Laura Baker, Tori Lenet, Lily Park, Sanjay Murthy, Reilly Musselman, Simarpreet Ichhpuniani, Tyler McKechnie, Jay Lee, Jeremy Biro, Yung Lee, Lily Park, Aristithes Doumouras, Dennis Hong, Cagla Eskicioglu, Garrett Johnson, Harminder Singh, Ramzi Helewa, Kristin Reynolds, Kathryn Sibley, Malcolm Doupe, Lisa Zhang, Kelly Brennan, Jennifer Flemming, Sulaiman Nanji, Shaila Merchant, Maya Djerboua, Antonio Caycedo-Marulanda, Sunil Patel, James Holden, Garrett Johnson, David Hochman, Ramzi Helewa, Jeongyoon Jenny Moon, Richard Garfinkle, Sophie Dell'Aniello, Phyllis Zelkowitz, Carol-Ann Vasilevsky, Paul Brassard, Marylise Boutros, Jeongyoon Jenny Moon, Amine Zoughlami, Wusiman Abibula, Alex Amar, Gabriela Ghitulescu, Carol-Ann Vasilevsky, Paul Brassard, Marylise Boutros, Jeongyoon Jenny Moon, Théa Araji, Allison Pang, Carol-Ann Vasilevsky, Marylise Boutros, Jeongyoon Jenny Moon, Alexa Ehlebracht, Julio Faria, Gabriela Ghitulescu, Nancy Morin, Allison Pang, Carol-Ann Vasilevsky, Marylise Boutros, Tiffany Paradis, Stephan Robitaille, Mahalia Oliver, Patrick Charlebois, Barry Stein, Sender Liberman, Liane S Feldman, Lawrence Lee, Zubair Bayat, Erin Kennedy, Charles Victor, Anand Govindarajan, Sunil Patel, Lisa Zhang, Kelly Brennan, Maya Djerboua, Sulaiman Nanji, Shaila J Merchant, Antonio Caycedo-Marulanda, Jennifer Flemming, Michael Fares Maalouf, Stephan Robitaille, Ruxandra Penta, Makena Pook, Julio Flavio Fiore, Liane Feldman, Lawrence Lee, Alon Wachtel, Nathalie Wong-Chong, Daniel Marinescu, Sahir Bhatnagar, Nancy Morin, Gabriela Ghitulescu, Carol-Ann Vasilevsky, Julio Faria, Marylise Boutros, Victoria Baronas, Arif Arif, Gale Ladua, Eric Bhang, Carl Brown, Fergal Donellan, Heather Stuart, Jonathan Loree, Vanessa Wiseman, Sunil Patel, Lisa Zhang, Peter Hugh MacDonald, Shaila Merchant, Kathleen Wattie Barnett, Antonio Caycedo-Marulanda, Jessica Lie, Carl Brown, Ahmer Karimuddin, Heather Stuart, Amandeep Ghuman, Terry Phang, Manoj Raval, Hyea Min Yoon, Roy Hajjar, Gabriela Fragoso, Manon Oliero, Annie Calvé, Hervé Vennin Rendos, Emmanuel Gonzalez, Nicholas J B Brereton, Thibault Cuisiniere, Claire Gerkins, Souad Djediai, Borhane Annabi, Khoudia Diop, Bertrand Routy, Patrick Laplante, Jean-François Cailhier, Nassima Taleb, Hefzi Alratrout, François Dagbert, Rasmy Loungnarath, Herawaty Sebajang, Frank Schwenter, Ramses Wassef, Richard Ratelle, Eric Debroux, Carole Richard, Manuela M Santos, Alexa Ehlebracht, Doulia Hamad, Hatim Alsulaim, Olivia Monton, Daniel Marinescu, Allison Pang, Carol-Ann Vasilevsky, Marylise Boutros, Natasha Caminsky, Daniel Marinescu, Mohammed Alqahtani, Allison Pang, Gabriela Ghitulescu, Carol-Ann Vasilevsky, Marylise Boutros, Natasha Caminsky, Daniel Marinescu, Richard Garfinkle, Marylise Boutros, Richard Gilbert, Terry Zwiep, Joshua Greenberg, Tori Lenet, Reilly Musselman, Lara Williams, Isabelle Raiche, Daniel McIsaac, Kednapa Thavorn, Dean Fergusson, Husein Moloo, Geneviève Morin, Janyssa Charbonneau, Xavier Paré, Jonathan Frigault, François Letarte, Rebecca C Auer, Michael Ott, Paul Karanicolas, Muriel Brackstone, Shady Ashmalla, Joel Weaver, Vicky Tagalakis, Marylise Boutros, Peter Stotland, Antonio Caycedo-Marulanda, Husein Moloo, Shiva Jayaraman, Sunil Patel, Gregoire LeGal, Silvana Spadafora, Steven Maclellan, Daniel Trottier, Derek Jonker, Timothy Asmis, Ranjeeta Mallick, Timothy Ramsay, Marc Carrier, Terry Phang, Delaram Shojaei, Ali Motamedi, Anu Ghuman, Ahmer Karimuddin, Manoj Raval, Carl Brown, Delaram Shojaei, Jessica Hopkins, Haili Wang, Don Buie, Jessica Hopkins, Haili Wang, Don Buie, Yosef Levin, Nasra Al Busaidi, Fateme Rajabiyazdi, Marie Demian, Marylise Boutros, Armaghan Alam, Ameer Farooq, Carl Brown, Terry Phang, Amandeep Ghuman, Ahmer Karimuddin, Manoj Raval, Farhad Udwadia, Natasha Caminsky, Daniel Marinescu, Mohammed Alqahtani, Allison Pang, Carol-Ann Vasilevsky, Marylise Boutros, Sarah Mansouri, Sonia Cheng Oviedo, Nathalie McFadden, Philip Lagace, Richard Spence, Greg Hirsch, Katerina Neumann, Philip Lagace, Katerina Neumann, Richard Spence, Charbel El-Kefraoui, Garrett Johnson, Harminder Singh, Ramzi Helewa, Marguerite Mainprize, Ayse Yilbas, Fernando Spencer Netto, Joel Katz, Megan Melland-Smith, Bree Sharma, Usman Khan, Markus Selzner, Kevin Verhoeff, Valentin Mocanu, Jerry Dang, Hillary Wilson, Noah Switzer, Daniel Birch, Shahzeer Karmali, Kevin Verhoeff, Valentin Mocanu, Uzair Jogiat, Hayley Forbes, Noah Switzer, Daniel Birch, Shahzeer Karmali, Khadija Nasser, Kevin Verhoeff, Valentin Mocanu, Janice Kung, Kieran Purich, Noah Switzer, Daniel Birch, Shahzeer Karmali, Olivier Mailloux, Nicolas Tassé, André Tchernof, Mélanie Nadeau, Philip Dawe, Andrew Beckett, Laurent Biertho, Kieran Purich, Andrea Lin, Kevin Verhoeff, Valentin Mocanu, Janice Y Kung, Daniel W Birch, Shahzeer Karmali, Noah J Switzer, Marta Whyte, Melinda Fowler-Woods, Amanda Fowler-Woods, Geraldine Shingoose, Andrew Hatala, Felicia Daeninck, Ashley Vergis, Krista Hardy, Kathleen Clouston, Ting Li, Estifanos Debru, Mirza Shaharyar Ahmad, Warren Sun, Jerry Dang, Noah Switzer, Daniel Birch, Shahzeer Karmali, Christopher De Gara, Warren Sun, Jennifer Halasz, Jerry Dang, Noah Switzer, Aliyah Kanji, Daniel Birch, Renuca Modi, Shahzeer Karmali, Hilalion San Ahn, Jeffrey Gu, Amer Jarrar, Nicole Kolozsvari, Yung Lee, Yasith Samarasinghe, Lucy Chen, Akithma Hapugall, Arshia Javidan, Tyler McKechnie, Aristithes Doumouras, Dennis Hong, Eileen Roach, Simon Laplante, Shannon Stogryn, Azusa Maeda, Timothy Jackson, Allan Okrainec, Alexandra Chow, Daniel Birch, Shahzeer Karmali, Aliyah Kanji, Noah Switzer, Jessica Trac, Michael Balas, Denise Gee, Matthew Hutter, Ozanan Meireles, James Jung, Wenjing He, Ashley Vergis, Krista Hardy, Karim Ramji, Vanessa Boudreau, Dennis Hong, Mehran Anvari, Pouya Iranmanesh, Karen Barlow, Tyler Cookson, Rafik Bolis, Harsha Shanthanna, Jonah Shiroky, Ekaterina Kouzmina, Shaidah Deghan, Boris Zevin, Cypriana Koziak, Zacharie Cloutier, Tyler Cookson, Karen Barlow, Vanessa Boudreau, Mehran Anvari, Intekhab Hossain, Jane Brodie, Erin O'Brien, Katherine Tedman-Aucoin, Diana Lawlor, Raleen Murphy, Laurie Twells, David Pace, James Ellsmere, Bradley Evans, Valentin Mocanu, Terry Zhang, Edward Deehan, Dina Kao, Naomi Hotte, Daniel Birch, Shahzeer Karmali, Kalutota Samarasinghe, Jens Walter, Karen Madsen, Nader Hanna, Erin Williams, Weidong Kong, Adam Fundytus, Christopher Booth, Sunil Patel, Antonio Caycedo-Marulanda, Wiley Chung, Sulaiman Nanji, Shaila Merchant, Matthew Castelo, Bettina Hansen, Lawrence Paszat, Nancy Baxter, Adena Scheer, Makena Pook, Tahereh Najafi Ghezeljeh, Maxime Lapointe-Gagner, Philip Nguyen-Powanda, Hiba Elhaj, Fateme Rajabiyazdi, Lawrence Lee, Liane S Feldman, Julio Fiore, Jesse Zuckerman, Rinku Sutradhar, Barbara Haas, Matthew Guttman, Antoine Eskander, Natalie Coburn, Tyler Chesney, Bourke Tillman, Victoria Zuk, Alyson Mahar, Amy Hsu, Wing Chan, Julie Hallet, Woo Jin Choi, Keegan Guidolin, Filomena Servidio-Italiano, Fayez Quereshy, Gonzalo Sapisochin, Akie Watanabe, Eitan Prisman, Elliot Mitmaker, Ross Walker, Jonn Wu, Anne Nguyen, Sam Wiseman, Bianka Saravana-Bawan, Dennis Hong, Michael Gupta, Jesse Pasternak, David Cyr, Omar Vergara-Fernandez, Amanpreet Brar, James Conner, Richard Kirsch, Mantaj Brar, Erin Kennedy, Anand Govindarajan, Robert Gryfe, Helen MacRae, Zane Cohen, Robin McLeod, Carol Swallow, Muriel Brackstone, Farhad Ghasemi, Victoria Ivankovic, Megan Delisle, Dawn Stacey, Jad Abou-Khalil, Fady Balaa, Kimberly Bertens, Brittney Dingley, Guillaume Martel, Kristen McAlpine, Carolyn Nessim, Shaheer Tadros, Marc Carrier, Rebecca Auer, Ananya Gopika Nair, David Lim, Dhruvin Hirpara, Antoine Eskander, Natalie Coburn, Rinku Sutradhar, Wing Chan, Julie Hallet, Cecily Stockley, Felicia Pickard, Alexander Mathieson, Michael Hogan, Melanie Seal, Deanna Ng, Belkacem Acidi, Wendy Johnston, Dario Callegaro, Savtaj Brar, Rebecca Gladdy, Peter Chung, Charles Catton, Korosh Khalili, Charles Honore, Carol Swallow, Shelly Luu, Ning Fu, Karineh Kazazian, Karina Pacholczyk, Deanna Ng, Jossie Swett-Cosentino, Paul Savage, Yukiko Shibahara, Sangeetha Kalimuthu, Osvaldo Espin-Garcia, James Conner, Jonathan Yeung, Gail Darling, Carol Swallow, Léamarie Meloche-Dumas, Frédéric Mercier, Victoria Barabash, Calvin Law, Natalie Coburn, Simron Singh, Sten Myrehaug, Wing Chan, Julie Hallet, Michael A D'Elia, Rebecca C Auer, Ashley Eom, Narry Muhn, Barbara Heller, Peter Lovrics, Katelynn Tang, Shawn Khan, Deanna Ng, Daniel Koerber, Eisar Al-Sukhni, David Cyr, Karineh Kazazian, Carol Swallow, Erika Schmitz, Sameer Apte, Carolyn Nessim, Ko Ta Chen, Judy Ban, Leo Chen, Elaine McKevitt, Rebecca Warburton, Jin-Si Pao, Carol Dingee, Urve Kuusk, Amy Bazzarelli, Jieun Newman-Bremang, Nicole Look Hong, Anna Gagliardi, Bryanna Nyhof, Kevin Verhoeff, Braulio Marfil-Garza, Gurpal Sandha, David Cooper, Khaled Dajani, David Bigam, Blaire Anderson, Tatsuya Kin, Anna Lam, Doug O'Gorman, Peter Senior, Camillo Ricordi, A M James Shapiro, Nic Jette, Michael Moser, Zuhaib Mir, Henry Lam, Jennifer Flemming, Diederick Jalink, Sulaiman Nanji, Sean Bennett, Christopher Griffiths, Betty Zhang, Kasia Tywonek, Brandon Meyers, Pablo Serrano, Luckshi Rajendran, Tori Lenet, Risa Shorr, Jad Abou-Khalil, Kimberly Bertens, Fady Balaa, Guillaume Martel, Jesse Zuckerman, Shiva Jayaraman, Alice Wei, Alyson Mahar, Yosuf Kaliwal, Guillaume Martel, Natalie Coburn, Julie Hallet, Woo Jin Choi, Phil Williams, Marco Claasen, Tommy Ivanics, Marina Englesakis, Steven Gallinger, Bettina Hansen, Gonzalo Sapisochin, Woo Jin Choi, Tommy Ivanics, Marco Claasen, Steven Gallinger, Bettina Hansen, Gonzalo Sapisochin, Richard Gilbert, Tori Lenet, Jad Abou-Khalil, Fady Balaa, Guillaume Martel, Alexandre Brind'Amour, Kimberly Bertens, Tori Lenet, Fady Balaa, Kimberly Bertens, Guillaume Martel, Jad Abou-Khalil, Nawal Amhis, Yves Collin, Marco Claasen, Tommy Ivanics, Christian Toso, Rene Adam, Jan Ijzermans, Gonzalo Sapisochin, Wojtek Polak, Sarah Mansouri, Maxime Léveillé, Christine Lawson, Yves Collin, Lee-Hwa Tai, Adriana Workewych, Brittany Greene, Shiva Jayaraman, Melanie Tsang, Alex Lee, Ahmed Al-Arnawoot, Luckshi Rajendran, Tyler Lamb, Anastasia Turner, Morgann Reid, Janelle Rekman, Richard Mimeault, Jad Abou-Khalil, Kimberly Bertens, Guillaume Martel, Fady Balaa, Evelyn Waugh, Chris Zhang, Madeline Lemke, Juan Glinka, Ken Leslie, Anton Skaro, Ephraim Tang, Alice Zhu, Brittany Greene, Melanie Tsang, Shiva Jayaraman, Helia Nabavian, Lev Bubis, Shiva Jayaraman, Melanie E Tsang, Jorge Roldan, Olivia Ganescu, Tsafrir Vanounou, Jean-Sébastien Pelletier, Andrew Lagrotteria, Brittany Greene, Melanie Tsang, Shiva Jayaraman, Jorge Roldan, Olivia Ganescu, Jean-Sébastien Pelletier, Tsafrir Vanounou, Luckshi Rajendran, Woo Jin Choi, Hala Muaddi, Tommy Ivanics, Marco P A W Classen, Gonzalo Sapisochin
No abstract text is available yet for this article.
2022: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://read.qxmd.com/read/36087094/dwelling-in-prolonged-grief-resting-state-functional-connectivity-during-oxytocin-and-placebo-administration
#38
JOURNAL ARTICLE
Saren H Seeley, Jessica R Andrews-Hanna, John J B Allen, Mary-Frances O'Connor
Clinical theories of adaptation in bereavement highlight a need for flexible shifting between mental states. However, prolonged motivational salience of the deceased partner may be a complicating factor, particularly when coupled with perseverative thinking about the loss. We investigated how prolonged grief symptoms might relate to resting state functional brain network connectivity in a sample of older adults (n = 38) who experienced the death of a partner 6-36 months prior, and whether intranasal oxytocin (as a neuropeptide involved in pair-bonding) had differential effects in participants with higher prolonged grief symptoms...
September 10, 2022: Human Brain Mapping
https://read.qxmd.com/read/35983227/development-of-a-composite-diffusion-tensor-imaging-score-correlating-with-short-term-neurological-status-in-neonatal-hypoxic-ischemic-encephalopathy
#39
JOURNAL ARTICLE
Kengo Onda, Eva Catenaccio, Jill Chotiyanonta, Raul Chavez-Valdez, Avner Meoded, Bruno P Soares, Aylin Tekes, Harisa Spahic, Sarah C Miller, Sarah-Jane Parker, Charlamaine Parkinson, Dhananjay M Vaidya, Ernest M Graham, Carl E Stafstrom, Allen D Everett, Frances J Northington, Kenichi Oishi
Hypoxic-ischemic encephalopathy (HIE) is the most common cause of neonatal acquired brain injury. Although conventional MRI may predict neurodevelopmental outcomes, accurate prognostication remains difficult. As diffusion tensor imaging (DTI) may provide an additional diagnostic and prognostic value over conventional MRI, we aimed to develop a composite DTI (cDTI) score to relate to short-term neurological function. Sixty prospective neonates treated with therapeutic hypothermia (TH) for HIE were evaluated with DTI, with a voxel size of 1 × 1 × 2 mm...
2022: Frontiers in Neuroscience
https://read.qxmd.com/read/35944723/plasma-biomarkers-of-evolving-encephalopathy-and-brain-injury-in-neonates-with-hypoxic-ischemic-encephalopathy
#40
JOURNAL ARTICLE
Ruoying Li, Jennifer K Lee, Rathinaswamy B Govindan, Ernest M Graham, Allen D Everett, Jamie Perin, Gilbert Vezina, Aylin Tekes, May W Chen, Frances Northington, Charlamaine Parkinson, Alexandra O'Kane, Meaghan McGowan, Colleen Krein, Tareq Al-Shargabi, Taeun Chang, An N Massaro
OBJECTIVE: The objective of the study was to evaluate the relationship between a panel of candidate plasma biomarkers and (1) death or severe brain injury on magnetic resonance imaging (MRI) and (2) dysfunctional cerebral pressure autoregulation as a measure of evolving encephalopathy. STUDY DESIGN: Neonates with moderate-to-severe hypoxic-ischemic encephalopathy (HIE) at 2 level IV neonatal intensive care units were enrolled into this observational study. Patients were treated with therapeutic hypothermia (TH) and monitored with continuous blood pressure monitoring and near-infrared spectroscopy...
January 2023: Journal of Pediatrics
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