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https://www.readbyqxmd.com/read/28903102/-abandonment-psychotherapy-for-suicidal-patients-with-borderline-personality-disorder-long-term-outcome
#1
Yvonne Burnand, Antonio Andreoli, Laura Frambati, Donna Manning, Alessandra Canuto, Allen Frances
No abstract text is available yet for this article.
September 14, 2017: Psychotherapy and Psychosomatics
https://www.readbyqxmd.com/read/28869403/misdiagnosing-donald-trump
#2
Allen Frances
No abstract text is available yet for this article.
September 4, 2017: Journal of Mental Health
https://www.readbyqxmd.com/read/28777935/de-novo-mutations-in-ywhag-cause-early-onset-epilepsy
#3
Ilaria Guella, Marna B McKenzie, Daniel M Evans, Sarah E Buerki, Eric B Toyota, Margot I Van Allen, Mohnish Suri, Frances Elmslie, Marleen E H Simon, Koen L I van Gassen, Delphine Héron, Boris Keren, Caroline Nava, Mary B Connolly, Michelle Demos, Matthew J Farrer
Massively parallel sequencing has revealed many de novo mutations in the etiology of developmental and epileptic encephalopathies (EEs), highlighting their genetic heterogeneity. Additional candidate genes have been prioritized in silico by their co-expression in the brain. Here, we evaluate rare coding variability in 20 candidates nominated with the use of a reference gene set of 51 established EE-associated genes. Variants within the 20 candidate genes were extracted from exome-sequencing data of 42 subjects with EE and no previous genetic diagnosis...
August 3, 2017: American Journal of Human Genetics
https://www.readbyqxmd.com/read/28770818/correction-lyme-borreliosis
#4
Allen C Steere, Strle Franc, Gary P Wormser, Linden T Hu, John A Branda, Joppe W R Hovius, Xin Li, Paul S Mead
This corrects the article DOI: 10.1038/nrdp.2016.90.
August 3, 2017: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/28684388/keith-conners
#5
Allen Frances, Bernard J Carroll
No abstract text is available yet for this article.
July 6, 2017: BMJ: British Medical Journal
https://www.readbyqxmd.com/read/28620996/feasibility-of-collecting-patient-reported-outcomes-for-inpatient-rehabilitation-quality-reporting
#6
Allen Walter Heinemann, Anne Deutsch, David Cella, Karon Frances Cook, Linda Foster, Ana Miskovic, Katharine Davis, Arielle Goldsmith
OBJECTIVE: To evaluate rehabilitation inpatients' willingness and ability to complete patient-reported outcomes (PROs) and the burden of completion on patients and staff. DATA SOURCES/STUDY SETTING: Two inpatient rehabilitation facilities. STUDY DESIGN: Patients with neurological disorders were assigned randomly to receive a nominal monetary incentive during or 1 month after the stay. DATA COLLECTION: Patients responded using a tablet computer or paper...
June 15, 2017: Health Services Research
https://www.readbyqxmd.com/read/28595457/how-people-with-dementia-and-their-carers-adapt-their-homes-a-qualitative-study
#7
Frances Allen, Rebecca Cain, Caroline Meyer
The objective was to explore the ways in which people with dementia and their carers adapt their homes, including the barriers and use of available information. Semi-structured interviews were conducted with 10 people with dementia and their informal carer. The collected data were analysed using thematic analysis. Three core themes emerged: Maintaining familiarity and coping with change, Having knowledge and finding knowledge and Meeting challenges through home adaptation. The most significant barriers to making home adaptations were lack of knowledge and maintaining familiarity...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/28575785/effect-of-season-of-birth-on-cord-blood-ige-and-ige-at-birth-a-systematic-review-and-meta-analysis
#8
REVIEW
Nugroho Harry Susanto, Don Vicendese, Agus Salim, Adrian J Lowe, Shyamali C Dharmage, Rachel Tham, Caroline Lodge, Frances Garden, Katie Allen, Cecilie Svanes, Joachim Heinrich, Michael J Abramson, Bircan Erbas
BACKGROUND: Elevated cord blood IgE is important on the pathway to allergic disease. The association between season of birth and infant cord blood IgE is not well-established. Study findings differ on which birth season is associated with higher cord blood IgE risk and its magnitude. We conducted a systematic review and meta-analysis of studies on season of birth and cord blood IgE. METHODS: We searched Medline, Web of Science, Scopus and ProQuest Health databases, and reviewed reference lists of articles that met the inclusion criteria...
August 2017: Environmental Research
https://www.readbyqxmd.com/read/28532329/adhd-a-critical-update-for-educational-professionals
#9
Sanne Te Meerman, Laura Batstra, Hans Grietens, Allen Frances
A medical approach towards behavioural problems could make professionals without a medical background, like teachers and other educational professionals feel inapt. In this article, we raise six scientifically grounded considerations regarding ADHD, currently the most prevalent childhood psychiatric diagnosis. These "need to knows" show just how misguided and potentially stigmatizing current conceptualizations of unruly behaviour have become. Some examples are given of how teachers are misinformed, and alternative ways of reporting about neuropsychological research are suggested...
June 2017: International Journal of Qualitative Studies on Health and Well-being
https://www.readbyqxmd.com/read/28505266/guidance-for-modifying-the-definition-of-diseases-a-checklist
#10
Jenny Doust, Per O Vandvik, Amir Qaseem, Reem A Mustafa, Andrea R Horvath, Allen Frances, Lubna Al-Ansary, Patrick Bossuyt, Robyn L Ward, Ina Kopp, Laragh Gollogly, Holger Schunemann, Paul Glasziou
Importance: No guidelines exist currently for guideline panels and others considering changes to disease definitions. Panels frequently widen disease definitions, increasing the proportion of the population labeled as unwell and potentially causing harm to patients. We set out to develop a checklist of issues, with guidance, for panels to consider prior to modifying a disease definition. Observations: We assembled a multidisciplinary, multicontinent working group of 13 members, including members from the Guidelines International Network, Grading of Recommendations Assessment, Development and Evaluation working group, and the World Health Organisation...
July 1, 2017: JAMA Internal Medicine
https://www.readbyqxmd.com/read/28490793/campanile-near-field-probes-fabricated-by-nanoimprint-lithography-on-the-facet-of-an-optical-fiber
#11
Giuseppe Calafiore, Alexander Koshelev, Thomas P Darlington, Nicholas J Borys, Mauro Melli, Aleksandr Polyakov, Giuseppe Cantarella, Frances I Allen, Paul Lum, Ed Wong, Simone Sassolini, Alexander Weber-Bargioni, P James Schuck, Stefano Cabrini, Keiko Munechika
One of the major challenges to the widespread adoption of plasmonic and nano-optical devices in real-life applications is the difficulty to mass-fabricate nano-optical antennas in parallel and reproducible fashion, and the capability to precisely place nanoantennas into devices with nanometer-scale precision. In this study, we present a solution to this challenge using the state-of-the-art ultraviolet nanoimprint lithography (UV-NIL) to fabricate functional optical transformers onto the core of an optical fiber in a single step, mimicking the 'campanile' near-field probes...
May 10, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28370412/pthrp-12-48-modulates-the-bone-marrow-microenvironment-and-suppresses-human-osteoclast-differentiation-and-lifespan
#12
Archana Kamalakar, Charity L Washam, Nisreen S Akel, Bethany J Allen, Diarra K Williams, Frances L Swain, Kim Leitzel, Allan Lipton, Dana Gaddy, Larry J Suva
Bone is a common site for metastasis in breast cancer patients and is associated with a series of complications that significantly compromise patient survival, partially due to the advanced stage of disease at the time of detection. Currently, no clinically-approved biomarkers can identify or predict the development of bone metastasis. We recently identified a unique peptide fragment of parathyroid hormone-related protein (PTHrP), PTHrP(12-48), as a validated serum biomarker in breast cancer patients that correlates with and predicts the presence of bone metastases...
July 2017: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/28190414/untrained-consumer-assessment-of-the-eating-quality-of-european-beef-2-demographic-factors-have-only-minor-effects-on-consumer-scores-and-willingness-to-pay
#13
S P F Bonny, G E Gardner, D W Pethick, P Allen, I Legrand, J Wierzbicki, L J Farmer, R J Polkinghorne, J-F Hocquette
The beef industry must become more responsive to the changing market place and consumer demands. An essential part of this is quantifying a consumer's perception of the eating quality of beef and their willingness to pay for that quality, across a broad range of demographics. Over 19 000 consumers from Northern Ireland, Poland, Ireland and France each tasted seven beef samples and scored them for tenderness, juiciness, flavour liking and overall liking. These scores were weighted and combined to create a fifth score, termed the Meat Quality 4 score (MQ4) (0...
February 13, 2017: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/28182813/second-malignant-neoplasms-in-childhood-cancer-survivors-treated-in-a-tertiary-paediatric-oncology-centre
#14
Jia Wei Lim, Frances Sh Yeap, Yiong Huak Chan, Allen Ej Yeoh, Thuan Chong Quah, Poh Lin Tan
Introduction: One of the most feared complications of childhood cancer treatment is second malignant neoplasms (SMNs). This study evaluates the incidence, risk factors and outcomes of SMNs in a tertiary paediatric oncology centre in Singapore. Materials and Methods: A retrospective review was conducted on patients diagnosed with childhood cancer under age 21 and treated at the National University Hospital, Singapore, from January 1990 to 15 April 2012. Case records of patients with SMNs were reviewed. Results: We identified 1124 cases of childhood cancers with a median follow-up of 3...
January 2017: Annals of the Academy of Medicine, Singapore
https://www.readbyqxmd.com/read/27976670/lyme-borreliosis
#15
REVIEW
Allen C Steere, Franc Strle, Gary P Wormser, Linden T Hu, John A Branda, Joppe W R Hovius, Xin Li, Paul S Mead
Lyme borreliosis is a tick-borne disease that predominantly occurs in temperate regions of the northern hemisphere and is primarily caused by the bacterium Borrelia burgdorferi in North America and Borrelia afzelii or Borrelia garinii in Europe and Asia. Infection usually begins with an expanding skin lesion, known as erythema migrans (referred to as stage 1), which, if untreated, can be followed by early disseminated infection, particularly neurological abnormalities (stage 2), and by late infection, especially arthritis in North America or acrodermatitis chronica atrophicans in Europe (stage 3)...
December 15, 2016: Nature Reviews. Disease Primers
https://www.readbyqxmd.com/read/27908594/rucaparib-in-relapsed-platinum-sensitive-high-grade-ovarian-carcinoma-ariel2-part-1-an-international-multicentre-open-label-phase-2-trial
#16
MULTICENTER STUDY
Elizabeth M Swisher, Kevin K Lin, Amit M Oza, Clare L Scott, Heidi Giordano, James Sun, Gottfried E Konecny, Robert L Coleman, Anna V Tinker, David M O'Malley, Rebecca S Kristeleit, Ling Ma, Katherine M Bell-McGuinn, James D Brenton, Janiel M Cragun, Ana Oaknin, Isabelle Ray-Coquard, Maria I Harrell, Elaina Mann, Scott H Kaufmann, Anne Floquet, Alexandra Leary, Thomas C Harding, Sandra Goble, Lara Maloney, Jeff Isaacson, Andrew R Allen, Lindsey Rolfe, Roman Yelensky, Mitch Raponi, Iain A McNeish
BACKGROUND: Poly(ADP-ribose) polymerase (PARP) inhibitors have activity in ovarian carcinomas with homologous recombination deficiency. Along with BRCA1 and BRCA2 (BRCA) mutations genomic loss of heterozygosity (LOH) might also represent homologous recombination deficiency. In ARIEL2, we assessed the ability of tumour genomic LOH, quantified with a next-generation sequencing assay, to predict response to rucaparib, an oral PARP inhibitor. METHODS: ARIEL2 is an international, multicentre, two-part, phase 2, open-label study done at 49 hospitals and cancer centres in Australia, Canada, France, Spain, the UK, and the USA...
January 2017: Lancet Oncology
https://www.readbyqxmd.com/read/27829474/untrained-consumer-assessment-of-the-eating-quality-of-beef-1-a-single-composite-score-can-predict-beef-quality-grades
#17
S P F Bonny, J-F Hocquette, D W Pethick, I Legrand, J Wierzbicki, P Allen, L J Farmer, R J Polkinghorne, G E Gardner
Quantifying consumer responses to beef across a broad range of demographics, nationalities and cooking methods is vitally important for any system evaluating beef eating quality. On the basis of previous work, it was expected that consumer scores would be highly accurate in determining quality grades for beef, thereby providing evidence that such a technique could be used to form the basis of and eating quality grading system for beef. Following the Australian MSA (Meat Standards Australia) testing protocols, over 19 000 consumers from Northern Ireland, Poland, Ireland, France and Australia tasted cooked beef samples, then allocated them to a quality grade; unsatisfactory, good-every-day, better-than-every-day and premium...
November 10, 2016: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/27760342/antiviral-cd8-t-cells-restricted-by-human-leukocyte-antigen-class-ii-exist-during-natural-hiv-infection-and-exhibit-clonal-expansion
#18
Srinika Ranasinghe, Pedro A Lamothe, Damien Z Soghoian, Samuel W Kazer, Michael B Cole, Alex K Shalek, Nir Yosef, R Brad Jones, Faith Donaghey, Chioma Nwonu, Priya Jani, Gina M Clayton, Frances Crawford, Janice White, Alana Montoya, Karen Power, Todd M Allen, Hendrik Streeck, Daniel E Kaufmann, Louis J Picker, John W Kappler, Bruce D Walker
CD8(+) T cell recognition of virus-infected cells is characteristically restricted by major histocompatibility complex (MHC) class I, although rare examples of MHC class II restriction have been reported in Cd4-deficient mice and a macaque SIV vaccine trial using a recombinant cytomegalovirus vector. Here, we demonstrate the presence of human leukocyte antigen (HLA) class II-restricted CD8(+) T cell responses with antiviral properties in a small subset of HIV-infected individuals. In these individuals, T cell receptor β (TCRβ) analysis revealed that class II-restricted CD8(+) T cells underwent clonal expansion and mediated killing of HIV-infected cells...
October 18, 2016: Immunity
https://www.readbyqxmd.com/read/27754716/storage-of-unfed-and-leftover-pasteurized-human-milk
#19
Ting Meng, Maryanne T Perrin, Jonathan C Allen, Jason Osborne, Frances Jones, April D Fogleman
OBJECTIVE: To determine the impact of storage on bacterial growth and immunological activity of pasteurized human milk and leftover pasteurized human milk that has been exposed to the microflora in an infant's mouth. MATERIALS AND METHODS: Eighteen mother-infant dyads participated in two separate studies. Mother's milk was pasteurized, and each baby was fed 1 to 2 ounces. Pasteurized and leftover pasteurized milk were stored at room (24°C) and refrigerated temperatures (4°C)...
December 2016: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/27575290/assessment-of-maximum-aerobic-capacity-and-anaerobic-threshold-of-elite-ballet-dancers
#20
Matthew A Wyon, Nick Allen, Ross Cloak, Sarah Beck, Paul Davies, Frances Clarke
An athlete's cardiorespiratory profile, maximal aerobic capacity, and anaerobic threshold is affected by training regimen and competition demands. The present study aimed to ascertain whether there are company rank differences in maximal aerobic capacity and anaerobic threshold in elite classical ballet dancers. Seventy-four volunteers (M 34, F 40) were recruited from two full-time professional classical ballet companies. All participants completed a continuous incremental treadmill protocol with a 1-km/hr speed increase at the end of each 1-min stage until termination criteria had been achieved (e...
September 2016: Medical Problems of Performing Artists
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