keyword
https://read.qxmd.com/read/38535641/temperature-dependent-feedback-operations-of-triple-gate-field-effect-transistors
#1
JOURNAL ARTICLE
Taeho Park, Kyoungah Cho, Sangsig Kim
In this study, we examine the electrical characteristics of triple-gate feedback field-effect transistors (TG FBFETs) over a temperature range of -200 °C to 280 °C. With increasing temperature from 25 °C to 280 °C, the thermally generated charge carriers increase in the channel regions such that a positive feedback loop forms rapidly. Thus, the latch-up voltage shifts from -1.01 V (1.34 V) to -11.01 V (10.45 V) in the n -channel ( p -channel) mode. In contrast, with decreasing temperature from 25 °C to -200 °C, the thermally generated charge carriers decrease, causing a shift in the latch-up voltage in the opposite direction to that of the increasing temperature case...
March 9, 2024: Nanomaterials
https://read.qxmd.com/read/38534231/sensing-characteristics-of-sars-cov-2-spike-protein-using-aptamer-functionalized-si-based-electrolyte-gated-field-effect-transistor-egt
#2
JOURNAL ARTICLE
Seonghwan Shin, Sangwon Kim, Wonyeong Choi, Jeonghyeon Do, Jongmin Son, Kihyun Kim, Sungkey Jang, Jeong-Soo Lee
The sensing responses of SARS-CoV-2 spike protein using top-down-fabricated Si-based electrolyte-gated transistors (EGTs) have been investigated. An aptamer was employed as a receptor for the SARS-CoV-2 spike protein. The EGT demonstrated excellent intrinsic characteristics and higher sensitivity in the subthreshold regime compared to the linear regime. The limit of detection (LOD) was achieved as low as 0.94 pg/mL and 20 pg/mL for the current and voltage sensitivity, respectively. To analyze the sensing responses of EGT in detecting the aptamer-SARS-CoV-2 spike protein conjugate, a lumped-capacitive model with the presence of an effective dipole potential and an effective capacitance of the functionalized layer component was employed...
February 26, 2024: Biosensors
https://read.qxmd.com/read/38533447/research-on-adults-with-subthreshold-depression-after-aerobic-exercise-a-resting-state-fmri-study-based-on-regional-homogeneity-reho
#3
JOURNAL ARTICLE
Wenbin Shen, Xiaoxiao Wang, Qin Li, Qingguo Ding, Hongqiang Zhang, Zheng Qian, Zhixin Sun, Xingyu Chen, Jun Zhang, Mengqi Zhao, Lina Huang, Wei Xing
OBJECTIVE: Subthreshold depression (StD)/subsyndromal depression refers to a threatening precursor to depression. Aerobic exercise is a promising self-supportive adjunctive intervention and an effective measure for StD. Our study utilizes regional homogeneity (ReHo) to investigate the impact of aerobic exercise on resting-state brain function. METHODS: A total of 78 subjects, aged between 18 and 48 years, (StD group, n = 44; healthy control (HC) group, n = 34) engaged in moderate-intensity aerobic exercise 3-4 times per week for 8 weeks...
2024: Frontiers in Neuroscience
https://read.qxmd.com/read/38531112/high-%C3%AE%C2%BA-dielectric-hfo-2-2d-semiconductor-hfse-2-gate-stack-for-low-power-steep-switching-computing-devices
#4
JOURNAL ARTICLE
Taeho Kang, Joonho Park, Hanggyo Jung, Haeju Choi, Sang-Min Lee, Nayeong Lee, Ryong-Gyu Lee, Gahye Kim, Seung-Hwan Kim, Hyung-Jun Kim, Cheol-Woong Yang, Jongwook Jeon, Yong-Hoon Kim, Sungjoo Lee
Herein, we report a high-quality gate stack (native HfO2 formed on 2D HfSe2 ) fabricated via plasma oxidation, realizing an atomically sharp interface with a suppressed interface trap density (Dit ∼ 5×1010 cm-2 eV-1 ). The chemically converted HfO2 exhibits dielectric constant, κ ∼ 23, resulting in low gate leakage current (∼10-3 A/cm2 ) at EOT ∼0.5 nm. Density functional calculations indicated that the atomistic mechanism for achieving a high-quality interface is the possibility of O atoms replacing the Se atoms of the interfacial HfSe2 layer without a substitution energy barrier, allowing layer-by-layer oxidation to proceed...
March 26, 2024: Advanced Materials
https://read.qxmd.com/read/38528108/quantum-interference-enhances-the-performance-of-single-molecule-transistors
#5
JOURNAL ARTICLE
Zhixin Chen, Iain M Grace, Steffen L Woltering, Lina Chen, Alex Gee, Jonathan Baugh, G Andrew D Briggs, Lapo Bogani, Jan A Mol, Colin J Lambert, Harry L Anderson, James O Thomas
Quantum effects in nanoscale electronic devices promise to lead to new types of functionality not achievable using classical electronic components. However, quantum behaviour also presents an unresolved challenge facing electronics at the few-nanometre scale: resistive channels start leaking owing to quantum tunnelling. This affects the performance of nanoscale transistors, with direct source-drain tunnelling degrading switching ratios and subthreshold swings, and ultimately limiting operating frequency due to increased static power dissipation...
March 25, 2024: Nature Nanotechnology
https://read.qxmd.com/read/38526847/integration-of-ultrathin-hafnium-oxide-with-a-clean-van-der-waals-interface-for-two-dimensional-sandwich-heterostructure-electronics
#6
JOURNAL ARTICLE
Yumei Jing, Xianfu Dai, Junqiang Yang, Xiaobin Zhang, Zhongwang Wang, Xiaochi Liu, Huamin Li, Yahua Yuan, Xuefan Zhou, Hang Luo, Dou Zhang, Jian Sun
Integrating high-κ dielectrics with a small equivalent oxide thickness (EOT) with two-dimensional (2D) semiconductors for low-power consumption van der Waals (vdW) heterostructure electronics remains challenging in meeting both interface quality and dielectric property requirements. Here, we demonstrate the integration of ultrathin amorphous HfO x sandwiched within vdW heterostructures by the selective thermal oxidation of HfSe2 precursors. The self-cleaning process ensures a high-quality interface with a low interface state density of 1011 -1012 cm-2 eV-1 ...
March 25, 2024: Nano Letters
https://read.qxmd.com/read/38523789/cortical-brain-organoid-slices-cbos-for-the-study-of-human-neural-cells-in-minimal-networks
#7
JOURNAL ARTICLE
Laura Petersilie, Sonja Heiduschka, Joel S E Nelson, Louis A Neu, Stephanie Le, Ruchika Anand, Karl W Kafitz, Alessandro Prigione, Christine R Rose
Brain organoids derived from human pluripotent stem cells are a promising tool for studying human neurodevelopment and related disorders. Here, we generated long-term cultures of cortical brain organoid slices (cBOS) grown at the air-liquid interphase from regionalized cortical organoids. We show that cBOS host mature neurons and astrocytes organized in complex architecture. Whole-cell patch-clamp demonstrated subthreshold synaptic inputs and action potential firing of neurons. Spontaneous intracellular calcium signals turned into synchronous large-scale oscillations upon combined disinhibition of NMDA receptors and blocking of GABAA receptors...
April 19, 2024: IScience
https://read.qxmd.com/read/38518552/brain-network-hierarchy-reorganization-in-subthreshold-depression
#8
JOURNAL ARTICLE
Xiaolong Yin, Junchao Yang, Qing Xiang, Lixin Peng, Jian Song, Shengxiang Liang, Jingsong Wu
BACKGROUND: Hierarchy is the organizing principle of human brain network. How network hierarchy changes in subthreshold depression (StD) is unclear. The aim of this study was to investigate the altered brain network hierarchy and its clinical significance in patients with StD. METHODS: A total of 43 patients with StD and 43 healthy controls matched for age, gender and years of education participated in this study. Alterations in the hierarchy of StD brain networks were depicted by connectome gradient analysis...
March 18, 2024: NeuroImage: Clinical
https://read.qxmd.com/read/38517941/modelling-and-analysis-of-camp-induced-mixed-mode-oscillations-in-cortical-neurons-critical-roles-of-hcn-and-m-type-potassium-channels
#9
JOURNAL ARTICLE
Matteo Martin, Morten Gram Pedersen
Cyclic AMP controls neuronal ion channel activity. For example hyperpolarization-activated cyclic nucleotide-gated (HCN) and M-type K+ channels are activated by cAMP. These effects have been suggested to be involved in astrocyte control of neuronal activity, for example, by controlling the action potential firing frequency. In cortical neurons, cAMP can induce mixed-mode oscillations (MMOs) consisting of small-amplitude, subthreshold oscillations separating complete action potentials, which lowers the firing frequency greatly...
March 22, 2024: PLoS Computational Biology
https://read.qxmd.com/read/38516489/postoperative-patient-pain-severity-and-its-association-with-anxiety-depression-and-sleep-quality
#10
JOURNAL ARTICLE
Mariwan Husni, Haitham Jahrami, Hamdi Al Shenawi, Saleh F Alenenzi, Faisal N Alhawas, Mohammed A Asiri, Fayza Haider, Ahmad F Alanazi, Rami J Yaghan
Introduction The experience of pain is a complex phenomenon. A patient in the acute postsurgical pain setting may feel a constant bombardment of nociceptive input from the surgical site; this in turn influences psychological factors that determine the overall emotional experience of pain, which is significant. The aim of our study was to investigate the severity of pain in postsurgical patients three days after surgery using the 100 mm visual analog scale (VAS). Methods This was a cross-sectional assessment of postoperative pain...
February 2024: Curēus
https://read.qxmd.com/read/38516308/coherent-activity-within-and-between-hemispheres-cortico-cortical-connectivity-revealed-by-rtms-of-the-right-posterior-parietal-cortex
#11
JOURNAL ARTICLE
Chiara Mazzi, Sonia Mele, Chiara Bagattini, Javier Sanchez-Lopez, Silvia Savazzi
INTRODUCTION: Low frequency (1 Hz) repetitive transcranial stimulation (rTMS) applied over right posterior parietal cortex (rPPC) has been shown to reduce cortical excitability both of the stimulated area and of the interconnected contralateral homologous areas. In the present study, we investigated the whole pattern of intra- and inter-hemispheric cortico-cortical connectivity changes induced by rTMS over rPPC. METHODS: To do so, 14 healthy participants underwent resting state EEG recording before and after 30 min of rTMS at 1 Hz or sham stimulation over the rPPC (electrode position P6)...
2024: Frontiers in Human Neuroscience
https://read.qxmd.com/read/38508293/temporal-interference-stimulation-targets-deep-primate-brain
#12
JOURNAL ARTICLE
Ruobing Liu, Guanyu Zhu, Zhengping Wu, Yifei Gan, Jianguo Zhang, Jiali Liu, Liang Wang
Temporal interference (TI) stimulation, a novel non-invasive stimulation strategy, has recently been shown to modulate neural activity in deep brain regions of living mice. Yet, it is uncertain if this method is applicable to larger brains and whether the electric field produced under traditional safety currents can penetrate deep regions as observed in mice. Despite recent model-based simulation studies offering positive evidence at both macro- and micro-scale levels, the absence of electrophysiological data from actual brains hinders comprehensive understanding and potential application of TI...
March 18, 2024: NeuroImage
https://read.qxmd.com/read/38504415/exploring-sub-threshold-food-addiction-in-adult-patients-with-severe-obesity-a-cross-sectional-analysis
#13
JOURNAL ARTICLE
Aymery Constant, Mickaël Som, David Val-Laillet, Romain Moirand, Ronan Thibault
BACKGROUND: Most studies on Food Addiction (FA) used the strict classical diagnosis approach without quantifying sub-threshold symptoms (i.e. uncontrolled/excessive food intake, negative affect, craving, tolerance, withdrawal, and continued use despite harm) nor indicating where they stand on the "three-stage addiction cycle" modeling the transition from substance use to addiction. OBJECTIVES: (1) to estimate the proportion of clinically significant episodes of distress/impairment in severely obese patients without FA, and (2) to assess their associations with FA symptoms at the subthreshold level...
March 19, 2024: Journal of Addictive Diseases
https://read.qxmd.com/read/38499697/binary-and-ternary-logic-in-memory-using-nanosheet-feedback-field-effect-transistors-with-triple-gated-structure
#14
JOURNAL ARTICLE
Jongseong Han, Jaemin Son, Seungho Ryu, Kyoungah Cho, Sangsig Kim
In this study, we demonstrate binary and ternary logic-in-memory (LIM) operations of inverters and NAND and NOR gates comprising nanosheet (NS) feedback field-effect transistors (FBFETs) with a triple-gated structure. The NS FBFETs are reconfigured in p- or n-channel modes depending on the polarity of the gate bias voltage and exhibit steep switching characteristics with an extremely low subthreshold swing of 1.08 mV dec-1 and a high ON/OFF current ratio of approximately 107 . Logic circuits consisting of NS FBFETs perform binary and ternary logic operations of the inverters and NAND and NOR gates in each circuit and store their outputs under zero-bias conditions...
March 18, 2024: Scientific Reports
https://read.qxmd.com/read/38499543/turning-alterations-detected-by-mobile-health-technology-in-idiopathic-rem-sleep-behavior-disorder
#15
JOURNAL ARTICLE
Cinzia Zatti, Andrea Pilotto, Clint Hansen, Andrea Rizzardi, Marcello Catania, Robbin Romijnders, Leandro Purin, Maria P Pasolini, Eva Schaeffer, Andrea Galbiati, Luigi Ferini-Strambi, Daniela Berg, Walter Maetzler, Alessandro Padovani
Idiopathic REM sleep Behavior Disorder (iRBD) is a condition at high risk of developing Parkinson's disease (PD) and other alpha-synucleinopathies. The aim of the study was to evaluate subtle turning alterations by using Mobile health technology in iRBD individuals without subthreshold parkinsonism. A total of 148 participants (23 persons with polysomnography-confirmed iRBD without subthreshold parkinsonism, 60 drug-naïve PD patients, and 65 age-matched controls were included in this prospective cross-sectional study...
March 18, 2024: NPJ Parkinson's Disease
https://read.qxmd.com/read/38499003/neurological-metabolic-and-psychopathological-correlates-of-lifetime-suicidal-behaviour-in-major-depressive-disorder-without-current-suicide-ideation
#16
JOURNAL ARTICLE
Paolo Olgiati, Basilio Pecorino, Alessandro Serretti
INTRODUCTION: Suicidal behaviour (SB) has a complex aetiology. Although suicidal ideation (SI) is considered the most important risk factor for future attempts, many people who engage in SB do not report it. METHODS: We investigated neurological, metabolic, and psychopathological correlates of lifetime SB in two independent groups of patients with major depression (sample 1: n = 230; age: 18-65 years; sample 2: n = 258; age >60 years) who did not report SI during an index episode...
March 18, 2024: Neuropsychobiology
https://read.qxmd.com/read/38493236/predictors-of-health-related-quality-of-life-for-children-with-neurodevelopmental-conditions
#17
JOURNAL ARTICLE
Maryam Mahjoob, Robyn Cardy, Melanie Penner, Evdokia Anagnostou, Brendan F Andrade, Jennifer Crosbie, Elizabeth Kelley, Muhammad Ayub, Muhammad Ayub, Jessica Brian, Alana Iaboni, Russell Schachar, Stelios Georgiades, Rob Nicolson, Jessica Jones, Azadeh Kushki
Neurodevelopmental conditions can be associated with decreased health-related quality of life; however, the predictors of these outcomes remain largely unknown. We characterized the predictors of health-related quality of life (HRQoL) in a sample of neurodiverse children and youth. We used a cross-sectional subsample from the Province of Ontario Neurodevelopmental Disorders Network (POND) consisting of those children and young people in the POND dataset with complete study data (total n = 615; 31% female; age: 11...
March 16, 2024: Scientific Reports
https://read.qxmd.com/read/38492881/why-is-there-an-error-negativity-on-correct-trials-a-reappraisal
#18
JOURNAL ARTICLE
Céline Ramdani, Thierry Hasbroucq, Franck Vidal
In healthy subjects, the Error Negativity (Ne) was initially reported on errors and on partial errors, only. Later on, application of the Laplacian transformation to EEG data unmasked a Ne-like wave (Nc) that shares a main generator with the Ne, suggesting that the Nc is just a small Ne. However, the reason why a small Ne would persist on correct responses remains unclear. Now, sometimes, subthreshold EMG activations in the muscles corresponding to correct responses (not strong enough to reach the response threshold) can precede full-blown correct responses...
March 14, 2024: Neuroscience Letters
https://read.qxmd.com/read/38490588/children-of-trauma-survivors-influences-of-parental-posttraumatic-stress-and-child-perceived-parenting
#19
JOURNAL ARTICLE
Lucy J Allbaugh, Grace George, Torsten Klengel, Alex Profetto, Lucas Marinack, Fiona O'Malley, Kerry Ressler
BACKGROUND: Research has established a negative association between parental posttraumatic stress symptoms (PTSS), including subthreshold symptoms, and child physical and behavioral health outcomes. Such intergenerational transmission of risk has multiple possible mechanisms, including lack of positive parenting, increased negative parenting, shared environmental and contextual risks, and potential biological components such as shared genetics or even transmission of epigenetic risk. METHOD: This study examined 93 parent-child dyads (n = 171 participants total) from a mixed Urban-Suburban US metropolitan area to investigate the relations between parental PTSS and child-perceived parenting and child PTSS...
March 13, 2024: Journal of Affective Disorders
https://read.qxmd.com/read/38489156/flexible-high-temperature-mos-2-field-effect-transistors-and-logic-gates
#20
JOURNAL ARTICLE
Yixuan Zou, Peng Li, Caizhen Su, Jiawen Yan, Haojie Zhao, Zekun Zhang, Zheng You
High-temperature-resistant integrated circuits with excellent flexibility, a high integration level (nanoscale transistors), and low power consumption are highly desired in many fields, including aerospace. Compared with conventional SiC high-temperature transistors, transistors based on two-dimensional (2D) MoS2 have advantages of superb flexibility, atomic scale, and ultralow power consumption. However, MoS2 cannot survive at high temperature and drastically degrades above 200 °C. Here, we report MoS2 field-effect transistors (FETs) with top/bottom hexagonal boron nitride (h-BN) encapsulation and graphene electrodes...
March 15, 2024: ACS Nano
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