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https://www.readbyqxmd.com/read/28645119/the-application-of-enhanced-recovery-after-surgery-eras-fast-track-surgery-in-gastrectomy-for-gastric-cancer-a-systematic-review-and-meta-analysis
#1
REVIEW
Jie Ding, Benlong Sun, Peng Song, Song Liu, Hong Chen, Min Feng, Wenxian Guan
BACKGROUND: The study aimed to compare the safety and effectiveness of Enhanced recovery after surgery (ERAS) with conventional care in gastrectomy for gastric cancer. METHODS: Search strategy from Pubmed, Embase, Web of science, Cochrane library and reference lists was performed. The collected studies were randomized controlled trials and published only in English, and undergoing ERAS in gastrectomy for gastric cancer from January 1994 to August 2016. RESULTS: A total of eight studies including 801 patients were included...
June 20, 2017: Oncotarget
https://www.readbyqxmd.com/read/28643319/-progress-of-the-application-of-optical-coherence-tomography-in-gastrointestinal-tumor-surgery
#2
Yongsheng Li, Hao Liu, Haipeng Huang, Yu Zhu, Haijun Deng, Jiang Yu, Site Luo, Li Huo, Li Lin, Huikai Xie, Guoxin Li
Optical coherence tomography (OCT) is a real-time, cross-sectional optical imaging technology. It is analogous to ultrasonography, except that OCT uses light waves instead of sound waves, and can provide three-dimensional morphological images of living tissues with a micrometer resolution. Through the use of endoscopes, needles, catheters and laparoscopes, OCT has demonstrated tremendous imaging potential in tumor surgery. The current studies suggest that OCT has potential for clinical applications in the following fields of gastrointestinal tumor surgery: (1) Early tumor detection and diagnosis: OCT can distinguish differences between polyp tissue, normal tissue and malignant tissue...
June 25, 2017: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/28643135/preoperative-tumor-restaging-and-resectability-assessment-of-gastric-cancers-after-chemotherapy-diagnostic-accuracy-of-mdct-using-new-staging-criteria
#3
Ijin Joo, Se Hyung Kim, Su Joa Ahn, Eun Sun Lee, Cheong-Il Shin, Hyuk-Joon Lee, Han Kwang Yang
PURPOSE: To evaluate the diagnostic performance of preoperative MDCT for tumor restaging and determination of resectability in gastric cancers after chemotherapy using new staging criteria. METHODS: This retrospective study was approved by our institutional review board and the requirement for informed consent was waived. Thirty-seven patients with initially unresectable gastric cancers who had received chemotherapy followed by surgery were included. Two independent radiologists reviewed preoperative MDCT images to determine the TNM staging and rate the overall likelihood of resectability using a 5-point scale (5: definitely unresectable, 1: definitely resectable)...
June 22, 2017: Abdominal Radiology
https://www.readbyqxmd.com/read/28639136/long-term-oncologic-outcomes-of-robotic-gastrectomy-for-gastric-cancer-compared-with-laparoscopic-gastrectomy
#4
Kazutaka Obama, Yoo-Min Kim, Dae Ryong Kang, Taeil Son, Hyoung-Il Kim, Sung Hoon Noh, Woo Jin Hyung
BACKGROUND: Initial experiences with robotic gastrectomy (RG) for gastric cancer have demonstrated favorable short-term outcomes, suggesting that RG is an effective alternative to laparoscopic gastrectomy (LG). However, data on long-term survival and recurrence after RG for gastric cancer have yet to be reported. The objective of this study was to assess long-term outcomes after RG compared with LG. METHODS: We retrospectively evaluated 313 and 524 patients who underwent RG or LG, respectively, for gastric cancer between July 2005 and December 2009...
June 21, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28639135/histological-verification-of-the-usefulness-of-magnifying-endoscopy-with-narrow-band-imaging-for-horizontal-margin-diagnosis-of-differentiated-type-early-gastric-cancers
#5
Makomo Makazu, Kingo Hirasawa, Chiko Sato, Ryosuke Ikeda, Takehide Fukuchi, Yasuaki Ishii, Ryosuke Kobayashi, Hiroaki Kaneko, Masataka Taguri, Yoko Tateishi, Yoshiaki Inayama, Shin Maeda
BACKGROUND: Although magnifying endoscopy with narrow-band imaging (ME-NBI) can help identify the horizontal margin (HM) of early gastric cancer (EGC), little is known about the factors that can clarify the HM by using ME-NBI. We aimed to characterize the pathological features of lesions in which the HM was identified using ME-NBI. METHODS: The HMs of 639 differentiated-type EGCs treated with endoscopic submucosal dissection or surgery were analyzed using conventional endoscopy and ME-NBI...
June 21, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28639042/comparative-study-between-endoscopic-submucosal-dissection-and-surgery-in-patients-with-early-gastric-cancer
#6
Kyu Yeon Hahn, Chan Hyuk Park, Yong Kang Lee, Hyunsoo Chung, Jun Chul Park, Sung Kwan Shin, Yong Chan Lee, Hyoung-Il Kim, Jae-Ho Cheong, Woo Jin Hyung, Sung Hoon Noh, Sang Kil Lee
BACKGROUND: Endoscopic submucosal dissection (ESD) is accepted as a standard treatment in patients with early gastric cancer (EGC) who have a negligible risk of lymph node metastasis. The aim of this study was to compare the short-term and long-term outcomes between ESD and surgery in patients with EGC that fulfilled the expanded indication of ESD on their final pathologic report. METHODS: We reviewed the clinical data of patients who underwent gastric ESD and surgery between January 2007 and December 2012...
June 21, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28639037/long-term-oncological-outcomes-of-submucosal-manipulation-during-non-curative-endoscopic-submucosal-dissection-for-submucosal-invasive-gastric-cancer-a-multicenter-retrospective-study-in-japan
#7
Hirotaka Ito, Takuji Gotoda, Tsuneo Oyama, Noboru Kawata, Akiko Takahashi, Yoshikazu Yoshifuku, Shu Hoteya, Masahiro Nakagawa, Waku Hatta, Masaaki Hirano, Mitsuru Esaki, Mitsuru Matsuda, Ken Ohnita, Ryo Shimoda, Motoyuki Yoshida, Osamu Dohi, Jun Takada, Keiko Tanaka, Shinya Yamada, Tsuyotoshi Tsuji, Yoshiaki Hayashi, Naoki Nakaya, Tomohiro Nakamura, Tooru Shimosegawa
BACKGROUND: Sufficient information is not available on the extent to which lymph node metastasis (LNM) and prognosis are affected by submucosal manipulation during endoscopic submucosal dissection (ESD) for submucosal invasive gastric cancer (SMGC). We aimed to identify the effects of submucosal manipulation during ESD on LNM and prognosis in patients with SMGC. METHODS: From 19 institutions in Japan, 2526 patients who failed to meet the current curative criteria for ESD between 2000 and 2011 were recruited...
June 21, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28635173/laparoscopic-surgery-for-sigmoid-colon-cancer-after-multiple-operations-including-urinary-diversion-with-indiana-pouch-a-case-report
#8
Kazuya Iwamoto, Hidekazu Takahashi, Naotsugu Haraguchi, Junichi Nishimura, Taishi Hata, Chu Matsuda, Hirofumi Yamamoto, Tsunekazu Mizushima, Yuichiro Doki, Masaki Mori
A 73-year-old man with lower abdominal pain was diagnosed at our hospital with sigmoid colon cancer. He had previously undergone radical cystectomy with Indiana pouch construction and gastrectomy to treat bladder cancer and gastric cancer, respectively. We performed a laparoscopic Hartmann's operation with Japanese D3 lymph node dissection. We observed severe adhesion in the abdominal cavity; adhesions between the urostomy and sigmoid colon were particularly severe. The tumor had invaded to the distal rectum, which had adhered to the pubic bone and the previously reconstructed urinary pouch...
June 21, 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/28629870/tumor-stroma-ratio-is-an-independent-predictor-for-overall-survival-and-disease-free-survival-in-gastric-cancer-patients
#9
Paolo Aurello, Giammauro Berardi, Diego Giulitti, Antonio Palumbo, Simone Maria Tierno, Giuseppe Nigri, Francesco D'Angelo, Emanuela Pilozzi, Giovanni Ramacciato
BACKGROUND: Despite different prognostic factors have been already studied, patients undergoing potentially curative resection for gastric cancer, still have a poor outcome. There is therefore the need to identify novel prognostic factors. Recently, Tumor-Stroma Ratio (TSR) was proven to be associated with prognosis in different types of cancers. Aim of this study was to evaluate the prognostic value of TSR in gastric cancer patients. METHODS: 106 patients underwent gastrectomy between January 2004 and December 2015...
June 16, 2017: Surgeon: Journal of the Royal Colleges of Surgeons of Edinburgh and Ireland
https://www.readbyqxmd.com/read/28629379/laparoscopic-gastrectomy-in-obese-gastric-cancer-patients-a-comparative-study-with-non-obese-patients-and-evaluation-of-difference-in-laparoscopic-methods
#10
Ke Chen, Yu Pan, Shu-Ting Zhai, Jia-Qin Cai, Qi-Long Chen, Ding-Wei Chen, Yi-Ping Zhu, Yu Zhang, Ya-Ping Zhang, Hendi Maher, Xian-Fa Wang
BACKGROUND: Obesity is a growing epidemic around the world, and obese patients are generally regarded as high risk for surgery compared with normal weight patients. The purpose of this study was to evaluate the influence of obesity on the surgical outcomes of laparoscopic gastrectomy (LG) for gastric cancer. METHODS: We reviewed data for all patients undergoing LG for gastric cancer at our institute between October 2004 and December 2016. Patients were divided into non-obese and obese groups and the perioperative outcomes were compared...
June 19, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/28628714/advanced-real-time-multi-display-educational-system-armes-an-innovative-real-time-audiovisual-mentoring-tool-for-complex-robotic-surgery
#11
Joong Ho Lee, Eiji Tanaka, Yanghee Woo, Güner Ali, Taeil Son, Hyoung-Il Kim, Woo Jin Hyung
INTRODUCTION: The recent scientific and technologic advances have profoundly affected the training of surgeons worldwide. We describe a novel intraoperative real-time training module, the Advanced Robotic Multi-display Educational System (ARMES). METHODS: We created a real-time training module, which can provide a standardized step by step guidance to robotic distal subtotal gastrectomy with D2 lymphadenectomy procedures, ARMES. The short video clips of 20 key steps in the standardized procedure for robotic gastrectomy were created and integrated with TilePro™ software to delivery on da Vinci Surgical Systems (Intuitive Surgical, Sunnyvale, CA)...
June 19, 2017: Journal of Surgical Oncology
https://www.readbyqxmd.com/read/28626474/status-and-prospects-of-robotic-gastrectomy-for-gastric-cancer-our-experience-and-a-review-of-the-literature
#12
REVIEW
Sejin Lee, Taeil Son, Hyoung-Il Kim, Woo Jin Hyung
Since the first report of robotic gastrectomy, experienced laparoscopic surgeons have used surgical robots to treat gastric cancer and resolve problems associated with laparoscopic gastrectomy. However, compared with laparoscopic gastrectomy, the superiority of robotic procedures has not been clearly proven. There are several advantages to using robotic surgery for gastric cancer, such as reduced estimated blood loss during the operation, a shorter learning curve, and a larger number of examined lymph nodes than conventional laparoscopic gastrectomy...
2017: Gastroenterology Research and Practice
https://www.readbyqxmd.com/read/28625333/liver-metastases-from-gastric-carcinoma-a-case-report-and-review-of-the-literature
#13
Beata Polkowska-Pruszyńska, Karol Rawicz-Pruszyński, Bogumiła Ciseł, Robert Sitarz, Grażyna Polkowska, Witold Krupski, Wojciech P Polkowski
Gastric carcinoma (GC) is the fifth most common malignancy worldwide but the third leading cause of cancer death, and surgery remains the only curative treatment option. Prognosis of patients with liver metastases from gastric carcinoma (LMGC) is poor, and the optimal treatment of metastatic gastric cancer remains a matter of debate. In 2002, a 53-year-old male patient with GC and synchronous oligometastatic lesion in liver VIII segment underwent a total gastrectomy combined with metastasectomy. The pathologic diagnosis was stage IV gastric adenocarcinoma (pT3N2M1), which was treated with adjuvant chemotherapy (cisplatin, epirubicin, leucovorin, and 5-fluorouracil)...
May 2017: Current Problems in Cancer
https://www.readbyqxmd.com/read/28624049/failure-to-operate-on-resectable-gastric-cancer-implications-for-policy-changes-and-regionalization
#14
Heather A Frohman, Jeremiah T Martin, Anh-Thu Le, Sean P Dineen, Ching-Wei D Tzeng
BACKGROUND: A significant proportion of patients never receive curative-intent surgery for resectable gastric cancer (GC). The primary aims of this study were to identify disparities and targetable risk factors associated with failure to operate in the context of national trends in surgical rates for resectable GC. METHODS: The National Cancer Database was used to identify patients with resectable GC (adenocarcinoma, clinical stage IA-IIIC, 2004-2013). Multivariate modeling was used to identify predictors of resection and to analyze the impact of surgery on overall survival (OS)...
June 15, 2017: Journal of Surgical Research
https://www.readbyqxmd.com/read/28623524/does-a-laparoscopic-approach-attenuate-the-body-weight-loss-and-lean-body-mass-loss-observed-in-open-distal-gastrectomy-for-gastric-cancer-a-single-institution-exploratory-analysis-of-the-jcog-0912-phase-iii-trial
#15
Toru Aoyama, Tsutomu Sato, Tsutomu Hayashi, Takanobu Yamada, Haruhiko Cho, Takashi Ogata, Koji Oba, Takaki Yoshikawa
BACKGROUND: Laparoscopy-assisted distal gastrectomy (LADG) for gastric cancer may prevent the loss of body weight and lean body mass resulting from reduced surgical stress in comparison to open distal gastrectomy (ODG). A multicenter phase III trial conducted by the Japan Clinical Oncology Group (JCOG0912 trial) was performed to confirm the non-inferiority of LADG to ODG for stage I gastric cancer in terms of relapse-free survival. METHODS: This study was performed as a single-institution exploratory analysis using the data of the patients from our hospital who were enrolled in the JCOG0912 phase III trial...
June 16, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28621676/psychiatric-morbidity-and-its-impact-on-surgical-outcomes-for-esophageal-and-gastric-cancer-patients-a-nationwide-cohort-study
#16
Huan Song, Jianwei Zhu, Donghao Lu, Fang Fang, Weimin Ye, Lars Lundell, Jan Johansson, Mats Lindblad, Magnus Nilsson
BACKGROUND: Due to the lack of detailed clinical information, existed evidence regarding a link between psychiatric factors and adverse cancer prognosis was inclusive. RESULTS: We identified 1,340 patients (48.8%) with perioperative psychiatric morbidity. Preoperative psychiatric morbidity was significantly associated with both general and surgical complications within 30 days (RR = 1.3, 95% confidence interval [CI] 1.1-1.5), and the risk of death within 90 days (RR = 1...
June 2, 2017: Oncotarget
https://www.readbyqxmd.com/read/28619681/gastric-carcinoma-after-sleeve-gastrectomy-for-obesity
#17
Miljana Vladimirov, Uwe Hesse, Hubert J Stein
Obesity is associated with an increased risk of cancer development in the upper gastrointestinal tract. We present the case of a female patient with gastric carcinoma after sleeve gastrectomy. Before bariatric surgery, one rationale for performing routine endoscopy is to detect clinically relevant conditions with the potential to change the surgical procedure. After bariatric surgery in symptomatic patients and in patients with unspecific symptoms, early upper endoscopy should be performed to detect potential carcinomas of the upper gastrointestinal tract...
April 25, 2017: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/28616919/-effects-of-early-enteral-immunonutrition-on-postoperative-immune-function-and-rehabilitation-of-patients-with-gastric-cancer-and-nutritional-risk
#18
Chang-Bing Peng, Wen-Zhong Li, Rui Xu, Wen Zhuang
OBJECTIVES: To investigate the effects of early enteral immunonutrition on postoperative immune function and rehabilitation of gastric cancer patients with nutritional risk. METHODS: New hospitalized patients with gastric cancer were evaluated the nutrient status based on NRS 2002. The patients who scored between 3 to 5 points were randomized into two groups(30 cases for each group), and those in experimental group were given 7-d early postoperative enteral immune nutrition, those in control group were given normal nutrition...
May 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/28616743/the-long-term-survival-of-stage-iv-gastric-cancer-patients-with-conversion-therapy
#19
Kazuya Yamaguchi, Kazuhiro Yoshida, Toshiyuki Tanahashi, Takao Takahashi, Nobuhisa Matsuhashi, Yoshihiro Tanaka, Kazuaki Tanabe, Hideki Ohdan
PURPOSE: A retrospective study was performed to clarify the role of conversion therapy (surgery with a prospect of R0 resection performed in initially unresectable metastatic cancer that responded to the chemotherapy) in stage IV gastric cancer (GC). PATIENTS AND METHODS: We treated 259 stage IV GC patients with systemic chemotherapy at Gifu and Hiroshima University Hospitals between 2001-2013. Of these, 84 patients who were subsequently treated by surgery were classified into four categories according to our previously published classification of stage IV GC, and short- and long-term outcomes were analyzed...
June 14, 2017: Gastric Cancer
https://www.readbyqxmd.com/read/28616609/three-dimensional-computed-tomography-simulation-for-laparoscopic-lymph-node-dissection-in-the-treatment-of-proximal-gastric-cancer
#20
REVIEW
Hideki Sunagawa, Takahiro Kinoshita
Application of laparoscopic surgery (LS) has expanded worldwide in the various fields due to the potential advantage of being less invasive than open surgery; however difficulty in recognizing positional relationship of the organs is one of the disadvantages of this kind of surgery. In order to compensate this drawback, preoperative three-dimensional computed tomography (3D-CT) simulation is regarded as promising. In gastric cancer surgery, 3D-CT simulation seems particularly effective in the splenic hilar dissection, because this region is associated with remarkable anatomical variation with complexity...
2017: Translational Gastroenterology and Hepatology
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