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Contrast enhanced ultrasound testes

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https://www.readbyqxmd.com/read/28620930/prospective-multimodal-imaging-assessment-of-locally-advanced-cervical-cancer-patients-administered-by-chemoradiation-followed-by-radical-surgery-the-price-prospective-imaging-of-cervical-cancer-and-neoadjuvant-treatment-study-the-role-of-ultrasound
#1
A C Testa, G Ferrandina, F Moro, T Pasciuto, M C Moruzzi, I De Blasis, F Mascilini, E Foti, R Autorino, A Collarino, B Gui, G F Zannoni, M A Gambacorta, A L Valentini, V Rufini, G Scambia
OBJECTIVE: Chemoradiation-based neoadjuvant treatment followed by radical surgery is an alternative therapeutic strategy for locally advanced cervical cancer (LACC) -stage ≥ IB2 (except of IIA1)- but ultrasound variables used to predict neoadjuvant partial response are not well defined. The goal of this study was to prospectively analyze the potential role of transvaginal ultrasound (TVUS) in early predicting pathologically assessed residual disease in a large, single-institution series of LACC patients triaged to neoadjuvant treatment followed by radical surgery...
June 16, 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28598495/ultrasonography-for-endoleak-detection-after-endoluminal-abdominal-aortic-aneurysm-repair
#2
REVIEW
Iosief Abraha, Maria Laura Luchetta, Rita De Florio, Francesco Cozzolino, Giovanni Casazza, Piergiorgio Duca, Basso Parente, Massimiliano Orso, Antonella Germani, Paolo Eusebi, Alessandro Montedori
BACKGROUND: People with abdominal aortic aneurysm who receive endovascular aneurysm repair (EVAR) need lifetime surveillance to detect potential endoleaks. Endoleak is defined as persistent blood flow within the aneurysm sac following EVAR. Computed tomography (CT) angiography is considered the reference standard for endoleak surveillance. Colour duplex ultrasound (CDUS) and contrast-enhanced CDUS (CE-CDUS) are less invasive but considered less accurate than CT. OBJECTIVES: To determine the diagnostic accuracy of colour duplex ultrasound (CDUS) and contrast-enhanced-colour duplex ultrasound (CE-CDUS) in terms of sensitivity and specificity for endoleak detection after endoluminal abdominal aortic aneurysm repair (EVAR)...
June 9, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28597000/intraoperative-ultrasound-as-a-screening-modality-for-the-detection-of-liver-metastases-during-resection-of-primary-colorectal-cancer-a-systematic-review
#3
REVIEW
Signe Bremholm Ellebæk, Claus Wilki Fristrup, Michael Bau Mortensen
Colorectal cancer (CRC) is one of the most common cancer diseases worldwide. One in 4 patients with CRC will have a disseminated disease at the time of diagnosis and often in the form of synchronous liver metastases. Studies suggest that up to 30% of patients have non-recognized hepatic metastases during primary surgery for CRC. Intraoperative ultrasonography examination (IOUS) of the liver to detect liver metastases was considered the gold standard during open CRC surgery. Today laparoscopic surgery is the standard procedure, but laparoscopic ultrasound examination (LUS) is not performed routinely...
April 2017: Ultrasound International Open
https://www.readbyqxmd.com/read/28592361/ct-imaging-of-solid-renal-masses-pitfalls-and-solutions
#4
REVIEW
S Krishna, C A Murray, M D McInnes, R Chatelain, M Siddaiah, O Al-Dandan, S Narayanasamy, N Schieda
Computed tomography (CT) remains the first-line imaging test for the characterisation of renal masses; however, CT has inherent limitations, which if unrecognised, may result in errors. The purpose of this manuscript is to present 10 pitfalls in the CT evaluation of solid renal masses. Thin section non-contrast enhanced CT (NECT) is required to confirm the presence of macroscopic fat and diagnosis of angiomyolipoma (AML). Renal cell carcinoma (RCC) can mimic renal cysts at NECT when measuring <20 HU, but are usually heterogeneous with irregular margins...
June 4, 2017: Clinical Radiology
https://www.readbyqxmd.com/read/28588677/comparative-study-of-conventional-us-contrast-enhanced-us-and-enhanced-mr-for-the-follow-up-of-prostatic-radiofrequency-ablation
#5
Chao Feng, Bin Hu, Bing Hu, Lei Chen, Jia Li, Jin Huang
The aim of the present study was to evaluate and compare the effectiveness of different imaging methods during follow-up of prostatic radiofrequency ablation. Prostatic radiofrequency ablation (RFA) was performed in 20 healthy beagle dogs. Various imaging examinations were used to monitor the results of RFA, including conventional ultrasound (US), contrast enhanced ultrasound (CEUS) and enhanced magnetic resonance (MR). Imaging exams were performed at five phases: Immediately following RFA, one week later, one month later, three months later and six months later...
June 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/28557995/preparation-and-characterization-of-a-novel-silicon-modified-nanobubble
#6
Jia Liu, Bo Zhang, Maotong Li, Meijun Zhou, Fei Li, Xiuxian Huang, Min Pan, Li Xue, Fei Yan
Nanobubbles (NBs) opened a new field of ultrasound imaging. There is still no practical method to control the diameter of bubbles. In this study, we developed a new method to control the size by incorporating of silicon hybrid lipids into the bubble membrane. The range of particle size of resulting NBs is between 523.02 ± 46.45 to 857.18 ± 82.90, smaller than the conventional microbubbles. The size of resulting NBs increased with the decrease in amount of silicon hybrid lipids, indicating the diameter of NBs can be regulated through modulating the ratio of silicon hybrid lipids in the bubble shell...
2017: PloS One
https://www.readbyqxmd.com/read/28553196/diagnostic-imaging-of-hepatocellular-carcinoma-a-pictorial-essay
#7
Tomasz K Nowicki, Karolina Markiet, Edyta Szurowska
Hepatocellular carcinoma (HCC) is the most common primary liver cancer, which develops mostly in the setting of chronic liver disease. European Association for the Study of the Liver (EASL) and European Organization for Research and Treatment of Cancer (EORTC) prepared guidelines for screening, follow-up and diagnosis of HCC to facilitate decision making and optimize both diagnostic and therapeutic protocols. The review briefly describes etiology, epidemiology and histopathology of HCC and presents EASL-EORTC guidelines for surveillance and diagnosis of HCC...
May 2017: Current Medical Imaging Reviews
https://www.readbyqxmd.com/read/28545055/comparative-lytic-efficacy-of-rt-pa-and-ultrasound-in-porcine-versus-human-clots
#8
Shenwen Huang, Himanshu Shekhar, Christy K Holland
INTRODUCTION: Porcine thrombi are employed routinely in preclinical models of ischemic stroke. In this study, we examined the differential lytic susceptibility of porcine and human whole blood clots with and without the use of microbubbles and ultrasound (US) as an adjuvant. MATERIALS AND METHODS: An in vitro system equipped with time-lapse microscopy was used to evaluate recombinant tissue-plasminogen activator (rt-PA) lysis of porcine and human clots in the same species or cross species plasma...
2017: PloS One
https://www.readbyqxmd.com/read/28542533/ultrasonography-methods-for-predicting-malignancy-in-canine-mammary-tumors
#9
Marcus Antonio Rossi Feliciano, Ricardo Andrés Ramirez Uscategui, Marjury Cristina Maronezi, Ana Paula Rodrigues Simões, Priscila Silva, Beatriz Gasser, Leticia Pavan, Cibele Figueira Carvalho, Júlio Carlos Canola, Wilter Ricardo Russiano Vicente
The aim of this study was to evaluate and compare the efficacy of B-mode, Doppler, contrast-enhanced ultrasonography (CEUS), and Acoustic Radiation Force Impulse (ARFI) elastography in predicting malignancy in canine mammary masses. This was a prospective cohort study from 2014 to 2016, which included 153 bitches with one or more mammary masses. A total of 300 masses were evaluated by ultrasonography (B-mode, Doppler, CEUS, and ARFI) and subsequently classified as benign or malignant by histopathology. Each ultrasound parameters studied were compared between benign and malignant masses by Chi-square or Student tests and differences were considered significant when P < 0...
2017: PloS One
https://www.readbyqxmd.com/read/28522149/measuring-absolute-blood-perfusion-in-mice-using-dynamic-contrast-enhanced-ultrasound
#10
Abbas Shirinifard, Suresh Thiagarajan, Melissa D Johnson, Christopher Calabrese, András Sablauer
We investigated the feasibility of estimating absolute tissue blood perfusion using dynamic contrast-enhanced ultrasound (CEUS) imaging in mice. We developed a novel method of microbubble administration and a model-free approach to estimate absolute kidney perfusion, and explored the kidney as a reference organ to estimate absolute perfusion of a neuroblastoma tumor. We performed CEUS on the kidneys of CD1 nude mice using the VisualSonics VEVO 2100 imaging system. We estimated individual kidney blood perfusion using the burst-replenishment (BR) technique...
May 15, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28471148/clinical-imaging-in-patients-experiencing-chest-pain
#11
Angelo Silverio, Rodolfo Citro
Non-invasive imaging modalities integrate the clinical and laboratory diagnostic work-up of patients admitted in emergency department for chest pain. Transthoracic echocardiography is the first-line imaging tool because it is rapidly and widely available, bedside feasible and cost-effective. Even when a comprensive exam is not feasible, a fast focused ultrasound exam should be performed. Contrast enhanced computed tomography is an easily accessible tool with specific application in patients suspected for pulmonary embolism (PE) and acute coronary syndrome (ACS) according to the pre-test risk assessment and to the clinical status...
May 3, 2017: Minerva Cardioangiologica
https://www.readbyqxmd.com/read/28425493/characterization-of-different-microbubbles-in-assisting-focused-ultrasound-induced-blood-brain-barrier-opening
#12
Sheng-Kai Wu, Po-Chun Chu, Wen-Yen Chai, Shih-Tsung Kang, Chih-Hung Tsai, Ching-Hsiang Fan, Chih-Kuang Yeh, Hao-Li Liu
Microbubbles (MBs) serve as a critical catalyst to amplify local cavitation in CNS capillary lumen to facilitate focused ultrasound (FUS) to transiently open the blood-brain barrier (BBB). However, limited understanding is available regarding the effect of different microbubbles to induce BBB opening. The aim of this study is to characterize different MBs on their effect in FUS-induced BBB opening. Three MBs, SonoVue, Definity, and USphere, were tested, with 0.4-MHz FUS exposure at 0.62-1.38 of mechanical index (MI) on rats...
April 20, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28385584/a-study-of-the-clinical-utility-of-a-20-minute-secretin-stimulated-endoscopic-pancreas-function-test-and-performance-according-to-clinical-variables
#13
Luis F Lara, Morihito Takita, James S Burdick, Daniel C DeMarco, Ronnie R Pimentel, Tolga Erim, Marlon F Levy
BACKGROUND AND AIMS: Direct pancreas juice testing of bicarbonate, lipase, or trypsin after stimulation by secretin or cholecystokinin is used to determine exocrine function, a surrogate for diagnosing chronic pancreatitis (CP). Endoscopic pancreas function tests (ePFTs), where a peak bicarbonate concentration (PBC) ≥80 mEq/L in pancreas juice is considered normal, are now used more frequently. In this ePFT, aspirates start 35 minutes after secretin administration because pancreas output peaks 30 minutes after secretagogue administration...
April 3, 2017: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/28372458/hepatocellular-carcinoma-presenting-with-budd-chiari-syndrome-right-atrial-thrombus-and-pulmonary-emboli
#14
Luís C Lourenço, David V Horta, Sara F Alberto, Jorge Reis
A 47-year-old patient presented with a two-week history of right upper quadrant pain, abdominal distention and new onset of shortness of breath. He had a history of intravenous drug abuse, no alcohol consumption and denied any known liver disease. On physical examination, he was tachypneic and had dullness in the flanks. His blood analysis at admission was as follows: hemoglobin, 12.9 g/dL; leukocyte count, 6,800/uL; platelet count, 63,000/uL; INR, 2.1; serum creatinine, 1.27 mg/dL; liver biochemistry tests were notable for marginal derangement, HBsAg was negative, anti-HCV was positive, HCV RNA was 367,498 IU/ml and alpha-fetoprotein was 992 mg/dL...
April 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28363948/false-negative-contrast-enhanced-spectral-mammography-use-of-more-than-one-imaging-modality-and-application-of-the-triple-test-avoids-misdiagnosis
#15
Donna Taylor, Susan O'Hanlon, Bruce Latham
A 50-year-old woman presented with chest tenderness. On examination, both breasts were lumpy. Bilateral mammography showed heterogeneously dense parenchyma, with possible stromal distortion laterally on the right at the 0900 position. On ultrasound (US), a corresponding 13×9×10 mm irregular hypoechoic mass with internal vascularity was noted and both breasts had a complex heterogeneous fibroglandular background pattern. US-guided core biopsy with marker clip insertion was performed with the diagnosis of a grade 2 invasive ductal carcinoma (IDC)...
March 31, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28363670/using-the-analytic-hierarchy-process-for-prioritizing-imaging-tests-in-diagnosis-of-suspected-appendicitis
#16
Maria Agapova, Brian W Bresnahan, Ken F Linnau, Louis P Garrison, Mitchell Higashi, Larry Kessler, Beth Devine
RATIONALE AND OBJECTIVES: In clinical guideline or criteria development processes, such as those used in developing American College of Radiology Appropriateness Criteria (ACR AC), experts subjectively evaluate benefits and risks associated with imaging tests and make complex decisions about imaging recommendations. The analytic hierarchy process (AHP) decomposes complex decisions into structured smaller decisions, incorporates quantitative evidence and qualitative expert opinion, and promotes structured consensus building...
May 2017: Academic Radiology
https://www.readbyqxmd.com/read/28358677/ultrafast-synthetic-transmit-aperture-imaging-usta-using-hadamard-encoded-virtual-sources-with-overlapping-sub-apertures
#17
Ping Gong, Pengfei Song, Shigao Chen
The development of ultrafast ultrasound imaging offers great opportunities to improve imaging technologies such as shear wave elastography and ultrafast Doppler imaging. In Ultrafast imaging, there are trade-offs among image signal-to-noise ratio (SNR), resolution, and post-compounded frame rate. Various approaches have been proposed to solve this trade-off such as multiplane wave imaging or the attempts of implementing synthetic transmit aperture imaging. In this paper, we propose an Ultrafast Synthetic Transmit Aperture (USTA) imaging technique using Hadamard-encoded virtual sources with overlapping sub-apertures to enhance both image SNR and resolution without sacrificing frame rate...
March 24, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28332442/ultrasound-imaging-in-the-diagnosis-of-large-vessel-vasculitis
#18
Michael Czihal, Christian Lottspeich, Ulrich Hoffmann
Nowadays noninvasive vascular imaging has an important role in the diagnostic work-up of the large vessel vasculitides (LVV), most importantly giant cell arteritis (GCA) and Takayasu arteritis. Among the imaging modalities available, ultrasound (US) has several important advantages, including low costs, rapid and repetitive availability without exposure to radiation, and high spatial resolution for assessment of large and medium-sized arteries. Therefore, US can be regarded the first line imaging method in suspected LVV...
March 23, 2017: VASA. Zeitschrift Für Gefässkrankheiten
https://www.readbyqxmd.com/read/28288892/mr-image-guided-delivery-of-cisplatin-loaded-brain-penetrating-nanoparticles-to-invasive-glioma-with-focused-ultrasound
#19
Kelsie F Timbie, Umara Afzal, Abhijit Date, Clark Zhang, Ji Song, G Wilson Miller, Jung Soo Suk, Justin Hanes, Richard J Price
Systemically administered chemotherapeutic drugs are often ineffective in the treatment of invasive brain tumors due to poor therapeutic index. Within gliomas, despite the presence of heterogeneously leaky microvessels, dense extracellular matrix and high interstitial pressure generate a "blood-tumor barrier" (BTB), which inhibits drug delivery and distribution. Meanwhile, beyond the contrast MRI-enhancing edge of the tumor, invasive cancer cells are protected by the intact blood-brain barrier (BBB). Here, we tested whether brain-penetrating nanoparticles (BPN) that possess dense surface coatings of polyethylene glycol (PEG) and are loaded with cisplatin (CDDP) could be delivered across both the blood-tumor and blood-brain barriers with MR image-guided focused ultrasound (MRgFUS), and whether this treatment could control glioma growth and invasiveness...
March 11, 2017: Journal of Controlled Release: Official Journal of the Controlled Release Society
https://www.readbyqxmd.com/read/28280455/increasing-of-blood-brain-tumor-barrier-permeability-through-transcellular-and-paracellular-pathways-by-microbubble-enhanced-diagnostic-ultrasound-in-a-c6-glioma-model
#20
Jinlong Zhang, Heng Liu, Xuesong Du, Yu Guo, Xiao Chen, Shunan Wang, Jingqin Fang, Peng Cao, Bo Zhang, Zheng Liu, Weiguo Zhang
Most of the anticancer agents cannot be efficiently delivered into the brain tumor because of the existence of blood-brain tumor barrier (BTB). The objective of this study was to explore the effect of microbubble-enhanced diagnostic ultrasound (MEUS) on the BTB permeability and the possible mechanism. Glioma-bearing rats were randomized into three groups as follows: the microbubble-enhanced continued diagnostic ultrasound (MECUS) group; the microbubble-enhanced intermittent diagnostic ultrasound (MEIUS) group and the control group...
2017: Frontiers in Neuroscience
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