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Contrast enhanced ultrasound testes

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https://www.readbyqxmd.com/read/28932826/interobserver-variation-of-the-bolus-and-burst-method-for-pancreatic-perfusion-with-dynamic-contrast-enhanced-ultrasound
#1
Marcus Stangeland, Trond Engjom, Martin Mezl, Radovan Jirik, Odd Helge Gilja, Georg Dimcevski, Kim Nylund
PURPOSE: Dynamic contrast-enhanced ultrasound (DCE-US) can be used for calculating organ perfusion. By combining bolus injection with burst replenishment, the actual mean transit time (MTT) can be estimated. Blood volume (BV) can be obtained by scaling the data to a vessel on the imaging plane. The study aim was to test interobserver agreement for repeated recordings using the same ultrasound scanner and agreement between results on two different scanner systems. MATERIALS AND METHODS: Ten patients under evaluation for exocrine pancreatic failure were included...
June 2017: Ultrasound International Open
https://www.readbyqxmd.com/read/28926263/copper-sulfide-perfluorocarbon-nanodroplets-as-clinically-relevant-photoacoustic-ultrasound-imaging-agents
#2
Daniela Y Santiesteban, Diego S Dumani, Daniel Profili, Stanislav Y Emelianov
We have developed laser-activated perfluorocarbon nanodroplets containing copper sulfide nanoparticles (CuS NPs) for contrast-enhanced ultrasound and photoacoustic imaging. As potential clinical contrast agents, CuS NPs have favorable properties including biocompatibility, biodegradability and enhance contrast in photoacoustic images at clinically relevant depths. However, CuS NPs are not efficient optical absorbers when compared to plasmonic nanoparticles and therefore, contrast enhancement with CuS NPs is limited, requiring high concentrations to generate images with sufficient signal-to-noise ratio...
September 19, 2017: Nano Letters
https://www.readbyqxmd.com/read/28912893/the-role-of-nitric-oxide-during-sonoreperfusion-of-microvascular-obstruction
#3
Francois T H Yu, Xucai Chen, Adam C Straub, John J Pacella
Rationale: Microembolization during PCI for acute myocardial infarction can cause microvascular obstruction (MVO). MVO severely limits the success of reperfusion therapies, is associated with additional myonecrosis, and is linked to worse prognosis, including death. We have shown, both in in vitro and in vivo models, that ultrasound (US) and microbubble (MB) therapy (termed "sonoreperfusion" or "SRP") is a theranostic approach that relieves MVO and restores perfusion, but the underlying mechanisms remain to be established...
2017: Theranostics
https://www.readbyqxmd.com/read/28886723/pancreatic-injury-in-children-a-case-report-and-review-of-the-literature
#4
Fayza Haider, Mohammed Amin Al Awadhi, Eizat Abrar, Mooza Al Dossari, Hasan Isa, Husain Nasser, Hakima Al Hashimi, Sharif Al Arayedh
BACKGROUND: Trauma is the main cause of morbidity and mortality in the pediatric population. Blunt trauma to the abdomen accounts for the majority of abdominal injuries in children. Pancreatic injury, although uncommon (2 to 9%), is the fourth most common solid organ injury. Unlike other solid organ injuries, pancreatic trauma may be subtle and difficult to diagnose. Computed tomography currently is the imaging modality of choice. As the incidence of pancreatic injury in children sustaining blunt abdominal trauma is low, management remains a challenge...
September 9, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28885204/quantitative-evaluation-of-real-time-maximum-liver-capacity-limax-and-time-intensity-curve-tic-analysis-in-ceus-based-microperfusion
#5
M Haimerl, K Brünn, S Poelsterl, L P Beyer, I Wiesinger, C Stroszczynski, E-M Jung, P Wiggermann
PURPOSE: To compare the diagnostic performance of real-time maximum liver capacity (LiMAx) with dynamic contrast-enhanced ultrasound (CEUS)-based liver microcirculation. MATERIALS AND METHODS: 23 patients underwent liver function capacity (LiMAx) test and consecutive or previous CEUS examinations. A bolus injection of 1.4 ml sulfur hexafluoride microbubbles was administered for CEUS measurements (1-6 MHz) and quantitative perfusion analysis (TIC) was performed with an integrated perfusion software using stored cine-loops...
September 4, 2017: Clinical Hemorheology and Microcirculation
https://www.readbyqxmd.com/read/28871466/salting-out-enhanced-ionic-liquid-microextraction-with-a-dual-role-solvent-for-simultaneous-determination-of-trace-pollutants-with-a-wide-polarity-range-in-aqueous-samples
#6
Man Gao, Jingang Qu, Kai Chen, Lide Jin, Randy Alan Dahlgren, Huili Wang, Chengxia Tan, Xuedong Wang
In real aquatic environments, many occupational pollutants with a wide range of polarities coexist at nanogram to milligram per liter levels. Most reported microextraction methods focus on extracting compounds with similar properties (e.g., polarity or specific functional groups). Herein, we developed a salting-out-enhanced ionic liquid microextraction based on a dual-role solvent (SILM-DS) for simultaneous detection of tetracycline, doxycycline, bisphenol A, triclosan, and methyltriclosan, with log K ow ranging from -1...
September 4, 2017: Analytical and Bioanalytical Chemistry
https://www.readbyqxmd.com/read/28852319/combination-of-acoustic-radiation-force-impulse-imaging-serological-indexes-and-contrast-enhanced-ultrasound-for-diagnosis-of-liver-lesions
#7
Xiao-Lan Sun, Hui Yao, Qiong Men, Ke-Zhu Hou, Zhen Chen, Chang-Qing Xu, Li-Wei Liang
AIM: To assess the value of combined acoustic radiation force impulse (ARFI) imaging, serological indexes and contrast-enhanced ultrasound (CEUS) in distinguishing between benign and malignant liver lesions. METHODS: Patients with liver lesions treated at our hospital were included in this study. The lesions were divided into either a malignant tumor group or a benign tumor group according to pathological or radiological findings. ARFI quantitative detection, serological testing and CEUS quantitative detection were performed and compared...
August 14, 2017: World Journal of Gastroenterology: WJG
https://www.readbyqxmd.com/read/28846949/splenic-hamartoma-associated-with-thrombocytopenia-a-case-report
#8
Toshiaki Komo, Jun Hihara, Mikihiro Kanou, Toshihiko Kohashi, Ichiro Ohmori, Masanori Yoshimitsu, Takuhiro Ikeda, Akira Nakashima, Masashi Miguchi, Ichiko Yamakita, Hidenori Mukaida, Naoki Hirabayashi, Mayumi Kaneko
INTRODUCTION: Hamartomas are rare, benign tumors of the spleen. Few cases of splenic hamartomas associated with thrombocytopenia have been reported. PRESENTATION OF CASE: An asymptomatic 64-year-old man with myelodysplastic syndrome was found to have a splenic tumor. Laboratory tests were significant for thrombocytopenia, with a platelet count of 7.8×10(4)/μL. Ultrasonography showed splenomegaly (10.8×6.6cm), and a hypoechoic splenic mass (8.0×7.0cm). Color doppler ultrasound revealed blood flow within the mass, and the mass density was homogeneous on abdominal computed tomography (CT)...
August 10, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28845489/is-contrast-enhanced-ultrasonography-a-useful-tool-in-a-beginner-s-hand-how-much-can-a-computer-assisted-diagnosis-prototype-help-in-characterizing-the-malignancy-of-focal-liver-lesions
#9
Tudor Voicu Moga, Alina Popescu, Ioan Sporea, Mirela Danila, Ciprian David, Vasile Gui, Nicoleta Iacob, Gratian Miclaus, Roxana Sirli
AIM: Contrast enhanced ultrasound (CEUS) improved the characterization of focal liver lesions (FLLs), but is an operatordependent method. The goal of this paper was to test a computer assisted diagnosis (CAD) prototype and to see its benefit in assisting a beginner in the evaluation of FLLs. MATERIAL AND METHOD: Our cohort included 97 good quality CEUS videos[34% hepatocellular carcinomas (HCC), 12.3% hypervascular metastases (HiperM), 11.3% hypovascular metastases (HipoM), 24...
August 23, 2017: Medical Ultrasonography
https://www.readbyqxmd.com/read/28829305/extended-lifetime-in-vivo-pulse-stimulated-ultrasound-imaging
#10
James Wang, Christopher V Barback, Casey N Ta, Joi Weeks, Natalie Gude, Robert F Mattrey, Sarah L Blair, William C Trogler, Hotaik Lee, Andrew C Kummel
An on-demand long-lived ultrasound contrast agent that can be activated with single pulse stimulated imaging (SPSI) has been developed using hard shell liquid perfluoropentane filled silica 500 nm nanoparticles for tumor ultrasound imaging. SPSI was tested on LnCAP prostate tumor models in mice; tumor localization was observed after intravenous (IV) injection of the contrast agent. Consistent with enhanced permeability and retention, the silica nanoparticles displayed an extended imaging lifetime of 3.3 ± 1 days (mean ± standard deviation)...
August 17, 2017: IEEE Transactions on Medical Imaging
https://www.readbyqxmd.com/read/28808900/varying-ultrasound-power-level-to-distinguish-surgical-instruments-and-tissue
#11
Hongliang Ren, Banani Anuraj, Pierre E Dupont
We investigate a new framework of surgical instrument detection based on power-varying ultrasound images with simple and efficient pixel-wise intensity processing. Without using complicated feature extraction methods, we identified the instrument with an estimated optimal power level and by comparing pixel values of varying transducer power level images. The proposed framework exploits the physics of ultrasound imaging system by varying the transducer power level to effectively distinguish metallic surgical instruments from tissue...
August 15, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28806319/transient-segmental-enhancement-of-pyogenic-liver-abscess-a-comparison-between-contrast-enhanced-ultrasound-and-computed-tomography
#12
Kun Sun, Wei Zhu, Yan Luo, Yongzhong Li, Xiang Zhou
OBJECTIVE: This study aimed to investigate the correlation between the transient segmental enhancement (TSE) of liver abscesses on contrast-enhanced ultrasound (CEUS) imaging and contrast-enhanced computed tomography (CT) scans. METHODS: In total, 42 abscesses in 38 patients were evaluated with real-time CEUS and contrast-enhanced CT imaging. The CT imaging and CEUS examinations were performed within one to 2 days of each other in all cases. The initial reports of the observations of TSE on CEUS scans were correlated later with the findings of TSE on contrast-enhanced CT images...
August 12, 2017: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/28799124/comparison-between-free-breathing-radial-vibe-on-3-t-mri-and-endoscopic-ultrasound-for-preoperative-t-staging-of-resectable-oesophageal-cancer-with-histopathological-correlation
#13
Jinrong Qu, Hongkai Zhang, Zhaoqi Wang, Fengguang Zhang, Hui Liu, Zhidan Ding, Yin Li, Jie Ma, Zhongxian Zhang, Shouning Zhang, Yafeng Dong, Lina Jiang, Wei Zhang, Robert Grimm, Berthold Kiefer, Ihab R Kamel, Jianjun Qin, Hailiang Li
OBJECTIVES: To compare the T staging of resectable oesophageal cancer (OC) using radial VIBE (r-VIBE) and endoscopic ultrasound (EUS) with pathological confirmation of the T stage. METHODS: Forty-three patients with endoscopically proven OC and indeterminate T1/T2/T3/T4a stage by computed tomography (CT) and EUS were imaged on a 3-T magnetic resonance imaging (MRI) scanner. T stage was scored on MRI and EUS by two independent radiologists and one endoscopist, respectively, and compared with postoperative pathological findings...
August 10, 2017: European Radiology
https://www.readbyqxmd.com/read/28793871/diagnostic-accuracy-of-contrast-enhanced-ultrasound-for-characterization-of-kidney-lesions-in-patients-with-and-without-chronic-kidney-disease
#14
Emily Hueywen Chang, Wui Kheong Chong, Sandeep Kumar Kasoji, Julia Rose Fielding, Ersan Altun, Lee B Mullin, Jung In Kim, Jason Peter Fine, Paul Alexander Dayton, Wendy Kimryn Rathmell
BACKGROUND: Patients with chronic kidney disease are at increased risk of cystic kidney disease that requires imaging monitoring in many cases. However, these same patients often have contraindications to contrast-enhanced computed tomography and magnetic resonance imaging. This study evaluates the accuracy of contrast-enhanced ultrasound (CEUS), which is safe for patients with chronic kidney disease, for the characterization of kidney lesions in patients with and without chronic kidney disease...
August 9, 2017: BMC Nephrology
https://www.readbyqxmd.com/read/28783738/improvement-to-ultrasonographical-differential-diagnosis-of-gastric-lesions-the-value-of-contrast-enhanced-sonography-with-gastric-distention
#15
Tingting Li, Man Lu, Jun Song, Ping Wu, Xueqing Cheng, Zhenqi Zhang
OBJECTIVE: The purpose of this retrospective study is to evaluate the diagnostic value of contrast enhanced sonography plus gastric distention sonography, the Double Contrast-enhanced Ultrasound (DCUS) in gastric lesions. METHODS: 107 cases with pathology confirmed gastric lesions were retrospectively reviewed, DCUS and oral contrast agent ultrasound (US) were performed in all cases prior to operation. Perfusion parameters including arrival time (AT), peak intensity (PI), time to peak (TTP), and area under the curve (AUC) of the lesion and surrounding normal tissue were analyzed...
2017: PloS One
https://www.readbyqxmd.com/read/28779957/toward-a-standardization-of-ultrasound-scanners-for-dynamic-contrast-enhanced-ultrasonography-methodology-and-phantoms
#16
Stéphanie Pitre-Champagnat, Bénédicte Coiffier, Laurène Jourdain, Baya Benatsou, Ingrid Leguerney, Nathalie Lassau
The standardization of ultrasound scanners for dynamic contrast-enhanced ultrasonography (DCE-US) is mandatory for evaluation of clinical multicenter studies. We propose a robust method using a phantom for measuring the variation of the harmonic signal intensity obtained from the area under the time-intensity curve versus various contrast-agent concentrations. The slope of this measured curve is the calibration parameter. We tested our method on two devices from the same manufacturer (AplioXV and Aplio500, Toshiba, Tokyo, Japan) using the same settings as defined for a French multicenter study...
August 2, 2017: Ultrasound in Medicine & Biology
https://www.readbyqxmd.com/read/28746202/assessing-diagnostic-value-of-contrast-enhanced-ultrasound-and-contrast-enhanced-computed-tomography-in-detecting-small-hepatocellular-carcinoma-a-meta-analysis
#17
COMPARATIVE STUDY
Jiasheng Huang, Wei Chen, Shanwen Yao
BACKGROUND: This study aimed to compare the diagnostic values of contrast-enhanced ultrasound (CEUS) and contrast-enhanced computed tomography (CECT) in detecting small hepatocellular carcinoma (SHCC). METHODS: A series of related articles from 2001 to 2015 were searched in PubMed and Embase databases. Data from selected articles were pooled to analyze the sensitivity, specificity, positive likelihood ratio (PLR), negative likelihood ratio (NLR), diagnostic odds ratio (DOR), and summary receiver operating characteristic (SROC) curve using Meta-DiSc software...
July 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28731670/calcaneus-osteomyelitis-secondary-to-guthrie-test-case-report
#18
Tugce Tural Kara, Tugba Erat, Halil Ozdemir, Aysun Yahsi, Suat Fitoz, Ergin Ciftci, Erdal Incea
Calcaneus osteomyelitis is a rare infection in newborns. Invasive procedures, prematurity and low birth wight are some causative factors. The clinical signs may be mild. We report a neonate with calcaneous osteomyelitis which was secondary to a Guthrie test sample. She was admitted to hospital with swelling, redness and increased temperature on her heel. Superficial tissue ultrasound showed fluid collection with heavy content was observed on the posterior of the right foot. Puncture and drainage was performed and methicillin-susceptible Staphylococcus aureus was isolated from the drainage culture...
August 1, 2017: Archivos Argentinos de Pediatría
https://www.readbyqxmd.com/read/28715949/contrast-enhanced-ultrasound-for-assessing-renal-perfusion-impairment-and-predicting-acute-kidney-injury-to-chronic-kidney-disease-progression
#19
Wei Cao, Shuang Cui, Li Yang, Chunyi Wu, Jian Liu, Fang Yang, Youhua Liu, Jianping Bin, Fan Fan Hou
AIMS: Acute kidney injury (AKI) is increasingly recognized as a major risk factor leading to progression to chronic kidney disease (CKD). However, the diagnostic tools for predicting AKI to CKD progression are particularly lacking. Here, we tested the utility of contrast-enhanced ultrasound (CEUS) for predicting progression to CKD after AKI by using both mild (20-min) and severe (45-min) bilateral renal ischemia-reperfusion injury mice. RESULTS: Renal perfusion measured by CEUS reduced to 25% ± 7% and 14% ± 6% of the pre-ischemic levels in mild and severe AKI 1 h after ischemia (p < 0...
August 22, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28704281/the-diagnostic-value-of-3-dimensional-sampling-perfection-with-application-optimized-contrasts-using-different-flip-angle-evolutions-space-mri-in-evaluating-lower-extremity-deep-venous-thrombus
#20
Gang Wu, Ruyi Xie, Xiaoli Zhang, John Morelli, Xu Yan, Xiaolei Zhu, Xiaoming Li
OBJECTIVES: The aim of this study was to evaluate the diagnostic performance of noncontrast magnetic resonance imaging utilizing sampling perfection with application optimized contrasts using different flip angle evolutions (SPACE) in detecting deep venous thrombus (DVT) of the lower extremity and evaluating clot burden. MATERIALS AND METHODS: This prospective study was approved by the institutional review board. Ninety-four consecutive patients (42 men, 52 women; age range, 14-87 years; average age, 52...
July 12, 2017: Investigative Radiology
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