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Hypomania

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https://www.readbyqxmd.com/read/28811911/evaluation-of-the-13-item-hypomania-checklist-and-a-brief-3-item-manic-features-questionnaire-in-primary-care
#1
Sukhmeet Singh, Paul Scouller, Daniel J Smith
Aims and method The mean delay for bipolar disorder diagnosis is 10 years. Identification of patients with previous hypomania is challenging, sometimes resulting in misdiagnosis. The aims of this study were: (a) to estimate the proportion of primary care patients with depression currently taking antidepressants who have undiagnosed bipolar disorder and (b) to compare a brief 3-item manic features questionnaire with the Hypomania Checklist (HCL-13). The sample comprised patients with a recorded diagnosis of depression, either on long-term antidepressant therapy or with previous multiple courses of antidepressants...
August 2017: BJPsych Bulletin
https://www.readbyqxmd.com/read/28797561/self-reported-psychosis-like-experiences-in-patients-with-mood-disorders
#2
I Baryshnikov, J Suvisaari, K Aaltonen, M Koivisto, T Melartin, P Näätänen, K Suominen, B Karpov, M Heikkinen, J Oksanen, T Paunio, G Joffe, E Isometsä
BACKGROUND: Self-reported psychosis-like experiences (PEs) may be common in patients with mood disorders, but their clinical correlates are not well known. We investigated their prevalence and relationships with self-reported symptoms of depression, mania, anxiety, borderline (BPD) and schizotypal (SPD) personality disorders among psychiatric patients with mood disorders. METHODS: The Community Assessment of Psychic Experiences (CAPE-42), Mood Disorder Questionnaire (MDQ), McLean Screening Instrument (MSI), The Beck Depressive Inventory (BDI), Overall Anxiety Severity and Impairment Scale (OASIS) and Schizotypal Personality Questionnaire-Brief form (SPQ-B) were filled in by patients with mood disorders (n=282) from specialized care...
February 3, 2017: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/28783519/antimanic-activity-of-minocycline-in-a-gbr12909-induced-model-of-mania-in-mice-possible-role-of-antioxidant-and-neurotrophic-mechanisms
#3
Ana Isabelle G de Queiroz, Adriano José Maia Chaves Filho, Tatiane da Silva Araújo, Camila Nayane Carvalho Lima, Michel de Jesus Souza Machado, André F Carvalho, Silvania Maria Mendes Vasconcelos, David Freitas de Lucena, João Quevedo, Danielle Macedo
BACKGROUND: Mania/hypomania is the cardinal feature of bipolar disorder. Recently, single administration of the dopamine transporter (DAT) inhibitor, GBR12909, was related to mania-like alterations. In the present study we aimed at testing behavioral and brain oxidant/neurotrophic alterations induced by the repeated administration of GBR12909 and its prevention/reversal by the mood stabilizing drugs, lithium (Li) and valproate (VAL) as well as by the neuroprotective drug, minocycline (Mino)...
August 1, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28731778/a-pharmacologic-algorithm-for-youth-who-are-at-high-risk-for-bipolar-disorder
#4
Christopher D Schneck, Kiki D Chang, Manpreet K Singh, Melissa P DelBello, David J Miklowitz
OBJECTIVE: Depression and brief periods of manic symptoms are linked to a significant risk of progression to bipolar disorder (BD) in children who have a first-degree relative with BD I or II. However, little evidence exists to guide the pharmacologic management of children with these high-risk phenotypes. We propose a pharmacological treatment algorithm for high-risk youth and present results on its use in a study of children with a first-degree relative with BD. METHODS: Subjects were 40 youth (mean 12...
July 21, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28709880/low-intensity-transcranial-electric-stimulation-safety-ethical-legal-regulatory-and-application-guidelines
#5
REVIEW
A Antal, I Alekseichuk, M Bikson, J Brockmöller, A R Brunoni, R Chen, L G Cohen, G Dowthwaite, J Ellrich, A Flöel, F Fregni, M S George, R Hamilton, J Haueisen, C S Herrmann, F C Hummel, J P Lefaucheur, D Liebetanz, C K Loo, C D McCaig, C Miniussi, P C Miranda, V Moliadze, M A Nitsche, R Nowak, F Padberg, A Pascual-Leone, W Poppendieck, A Priori, S Rossi, P M Rossini, J Rothwell, M A Rueger, G Ruffini, K Schellhorn, H R Siebner, Y Ugawa, A Wexler, U Ziemann, M Hallett, W Paulus
Low intensity transcranial electrical stimulation (TES) in humans, encompassing transcranial direct current (tDCS), transcutaneous spinal Direct Current Stimulation (tsDCS), transcranial alternating current (tACS), and transcranial random noise (tRNS) stimulation or their combinations, appears to be safe. No serious adverse events (SAEs) have been reported so far in over 18,000 sessions administered to healthy subjects, neurological and psychiatric patients, as summarized here. Moderate adverse events (AEs), as defined by the necessity to intervene, are rare, and include skin burns with tDCS due to suboptimal electrode-skin contact...
June 19, 2017: Clinical Neurophysiology: Official Journal of the International Federation of Clinical Neurophysiology
https://www.readbyqxmd.com/read/28689181/subthreshold-hypomania-affects-half-of-patients-with-bipolar-disorder-presenting-with-depressive-symptoms
#6
EDITORIAL
Roger S McIntyre
No abstract text is available yet for this article.
July 8, 2017: Evidence-based Mental Health
https://www.readbyqxmd.com/read/28681620/the-burden-of-mood-disorder-cerebrovascular-disease-comorbidity-essential-neurobiology-psychopharmacology-and-physical-activity-interventions
#7
Michele Fornaro, Marco Solmi, Nicola Veronese, Domenico De Berardis, Elisabetta Filomena Buonaguro, Carmine Tomasetti, Giampaolo Perna, Antonio Preti, Mauro Giovanni Carta
Cardio-vascular diseases (CVDs) and CVD-related disorders (including cerebrovascular diseases; CBVDs) are a major public health concern as they represent the leading cause of mortality and morbidity in developed countries. Patients with CVDs and CBVDs co-morbid with mood disorders, especially bipolar disorder (BD) and major depressive disorder (MDD), suffer reduced quality-of-life and significant disability adjusted for years of life and mortality. The relationship between CVDs/CBVDs and mood disorders is likely to be bidirectional...
July 6, 2017: International Review of Psychiatry
https://www.readbyqxmd.com/read/28662455/borderline-personality-and-attention-deficit-hyperactivity-traits-in-childhood-are-associated-with-hypomanic-features-in-early-adulthood
#8
Sumit Mistry, Stanley Zammit, Valentina-Escott Price, Hannah J Jones, Daniel J Smith
BACKGROUND: There is limited understanding of the symptomatic development of bipolar disorder from childhood to early adulthood. AIMS: We assessed whether borderline personality disorder traits, ADHD, and emotional, behavioural and social difficulties during childhood were associated with hypomania assessed in young adulthood. METHOD: We used data from the Avon Longitudinal Study of Parents and Children (ALSPAC), to examine associations between measures of childhood psychopathology and lifetime hypomanic features assessed at age 22-23 years using the Hypomania Checklist-32 (HCL-32; n = 3372)...
October 15, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28659991/bupropion-maintenance-treatment-in-refractory-bipolar-depression-a-case-report
#9
Julia Dehning, Heinz Grunze, Armand Hausmann
BACKGROUND: The optimal duration of antidepressant treatment in bipolar depression appears to be controversial due to a lack of quality evidence, and guideline recommendations are either vague or contradictive. This is especially true for second line treatments such as bupropion that had not been subject to rigourous long term studies in Bipolar Disorder. CASE PRESENTATION: We report the case of a 75 year old woman who presented with treatment refractory bipolar depression...
2017: Clinical Practice and Epidemiology in Mental Health: CP & EMH
https://www.readbyqxmd.com/read/28629452/inhibitory-brainstem-reflexes-under-external-emotional-stimuli-in-bipolar-i-and-ii-disorders
#10
Qisha Zhu, Jiawei Wang, Chanchan Shen, Hongying Fan, Bingren Zhang, Guorong Ma, Yanxia Lu, Wei Wang
BACKGROUND: Bipolar disorder types I (BD I) and II (BD II) might present different dysfunctions of the cortex and brainstem, as reflected by the second exteroceptive suppression period of temporalis muscle activity (ES2) under different stimuli of external emotions. METHODS: This study included 30 BD I and 20 BD II patients, and 40 healthy volunteers. All participants were invited to answer the Mood Disorder Questionnaire, the Hypomania Checklist-32, and the Plutchik-van Praag Depression inventory, as well as to undergo the ES2 test under external emotional-stimuli (emotional pictures plus sounds) of Disgust, Erotica, Fear, Happiness, and Sadness...
June 19, 2017: BMC Psychiatry
https://www.readbyqxmd.com/read/28618249/an-integrative-study-of-motivation-and-goal-regulation-processes-in-subclinical-anxiety-depression-and-hypomania
#11
Joanne M Dickson, Sheri Johnson, Christopher D Huntley, Andrew Peckham, Peter J Taylor
Research has implicated motivation and goal regulation in susceptibility to mood disorders. We studied for the first time key facets of motivation and goal regulation concurrently in relation to affective symptoms. The cross-national sample comprised 510 university students from the United States (n = 279) and United Kingdom (n = 231). Participants completed self-report measures of motivation, conditional goal setting, urgency, depression, anxiety, and mania risk. Structural Equation Modeling results found that behavioral activation system scores correlated negatively with depression and positively with mania risk, but were unrelated to anxiety...
June 3, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28595099/circadian-rhythm-sleep-wake-disorders-as-predictors-for-bipolar-disorder-in-patients-with-remitted-mood-disorders
#12
Yoshikazu Takaesu, Yuichi Inoue, Kotaro Ono, Akiko Murakoshi, Kunihiro Futenma, Yoko Komada, Takeshi Inoue
BACKGROUND: Circadian rhythm dysfunction is thought to play a key role in the pathogenesis of bipolar disorder (BD). We focused on circadian rhythm sleep-wake disorders (CRSWD) as possible predictors for bipolar disorder in patients with remitted mood disorders. METHOD: One hundred four BD (41 type I and 63 type II) outpatients and 73 age- and sex-matched major depressive disorder (MDD) outpatients participated in this study. The subjects were asked to answer questionnaires including demographic variables, clinical course of the disorder, and family history of psychiatric disorders...
October 1, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28560617/a-case-study-of-negative-affixes-in-sadegh-hedayat-s-letters-the-effect-of-bipolar-mood-disorder
#13
Elmira Esmaeelpour, Fariba Ghatreh, Mandana Nourbakhsh
This research studies the morphological features found in Sadegh Hedayat's letters, who, based on linguistic and psychological studies, may have had bipolar disorder. It aims to assess the impact of various types of moods on the frequency of negative affixes through qualitative analysis of the letters' text. The letters are written in Persian, and include six negative derivational affixes. As bipolar disorder includes four episodes, all letters are analyzed on the basis of six negative affixes concerning the episodes using SPSS...
May 30, 2017: Journal of Psycholinguistic Research
https://www.readbyqxmd.com/read/28558366/antidepressant-induced-hypomania-mania-in-patients-with-major-depression-evidence-from-the-bridge-ii-mix-study
#14
Margherita Barbuti, Isabella Pacchiarotti, Eduard Vieta, Jean-Michel Azorin, Jules Angst, Charles L Bowden, Sergey Mosolov, Allan H Young, Giulio Perugi
BACKGROUND: The issue of antidepressant-induced mood switches to hypomania, mania, or mixed states within the course of mayor depressive disorder (MDD) has been a controversial topic. The present post-hoc analysis of the BRIDGE-II-MIX study focuses on the clinical features of patients with history of antidepressant-induced hypomania/mania (AIHM) in a large international sample of patients with major depressive episode (MDE). METHODS: 2811 subjects with major depression were enrolled in this multicentre cross-sectional study...
May 24, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28552295/transcranial-direct-current-stimulation-tdcs-for-bipolar-depression-a-systematic-review-and-meta-analysis
#15
REVIEW
Clément Dondé, Ali Amad, Isabel Nieto, André Russowsky Brunoni, Nicholas H Neufeld, Frank Bellivier, Emmanuel Poulet, Pierre-Alexis Geoffroy
OBJECTIVE: Bipolar disorder (BD) is a severe and recurrent brain disorder that can manifest in manic or depressive episodes. Transcranial Direct Current Stimulation (tDCS) has been proposed as a novel therapeutic modality for patients experiencing bipolar depression, for which standard treatments are often inefficient. While several studies have been conducted in this patient group, there has been no systematic review or meta-analysis that specifically examines bipolar depression. We aimed to address this gap in the literature and evaluated the efficacy and tolerability of tDCS in patients fulfilling DSM-IV-TR criteria for BD I, II, or BD not otherwise specified (NOS)...
August 1, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28503113/who-s-the-leader-mania-or-depression-predominant-polarity-and-alcohol-polysubstance-use-in-bipolar-disorders
#16
Delfina Janiri, Marco Di Nicola, Giovanni Martinotti, Luigi Janiri
BACKGROUND: Predominant polarity characterises patients who mainly manifest recurrences of depression or mania/hypomania. Alcohol use disorder (AUD) and polysubstance use (PSU), which often complicate bipolar disorder (BD) and affect its clinical course, can influence predominant polarity. Nevertheless, previous studies have not clarified if BD patients differ in predominant polarity from BD patients with substance use disorder (SUD) comorbidity. OBJECTIVE: The aim of this study was to compare predominant polarity between BD without SUD, BD with AUD and BD with PSU...
April 2017: Current Neuropharmacology
https://www.readbyqxmd.com/read/28488895/sleep-quality-chronotype-temperament-and-bipolar-features-as-predictors-of-depressive-symptoms-among-medical-students
#17
Łukasz Mokros, Andrzej Witusik, Julia Michalska, Wojciech Łężak, Michał Panek, Katarzyna Nowakowska-Domagała, Adam Antczak, Tadeusz Pietras
The assessment of risk factors is a crucial step in the prevention and treatment of affective disorders and should encompass personal dispositions. The aim of this study was to assess the value of chronotype and temperament as independent predictors of depressive symptoms among medical students. The study surveyed 140 students of the Faculty of Medicine with a battery of questionnaires: the Beck Depression Index (BDI), Hypomania Checklist 32 (HCL-32), Pittsburgh Sleep Quality Index (PSQI), Chronotype Questionnaire and Eysenck Personality Questionnaire Revised...
May 10, 2017: Chronobiology International
https://www.readbyqxmd.com/read/28462772/mixed-features-in-major-depressive-disorder-diagnoses-and-treatments
#18
REVIEW
Trisha Suppes, Michael Ostacher
For the first time in 20 years, the American Psychiatric Association (APA) updated the psychiatric diagnostic system for mood disorders in the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5). Perhaps one of the most notable changes in the DSM-5 was the recognition of the possibility of mixed symptoms in major depression and related disorders (MDD). While MDD and bipolar and related disorders are now represented by 2 distinct chapters, the addition of a mixed features specifier to MDD represents a structural bridge between bipolar and major depression disorders, and formally recognizes the possibility of a mix of hypomania and depressive symptoms in someone who has never experienced discrete episodes of hypomania or mania...
April 2017: CNS Spectrums
https://www.readbyqxmd.com/read/28449569/baclofen-abuse-due-to-its-hypomanic-effect-in-patients-with-alcohol-dependence-and-comorbid-major-depressive-disorder
#19
Soumitra Ghosh, Dhrubajyoti Bhuyan
Baclofen is a gamma-aminobutyric acid type B receptor agonist used as an anti-craving agent for treatment of alcohol dependence. It has gained popularity in the recent times because it is well tolerated even in patients with hepatic impairments. Herein we are summarizing the latest literature about baclofen induced hypomania and are reporting a case of baclofen abuse because of its mood elevating property in a patient of alcohol dependence with comorbid major depressive disorder. Literature review and case study of a 36-year-old male with alcohol dependence with comorbid major depressive disorder was prescribed with tablet baclofen as an anti-craving agent along with antidepressant medicines...
May 31, 2017: Clinical Psychopharmacology and Neuroscience: the Official Scientific Journal of the Korean College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28447333/efficacy-and-tolerability-of-lithium-in-treating-acute-mania-in-youth-with-bipolar-disorder-protocol-for-a-systematic-review
#20
A Duffy, S Patten, S Goodday, A Weir, N Heffer, A Cipriani
BACKGROUND: Epidemiological, clinical, and high-risk studies have provided evidence that the peak period for onset of diagnosable episodes of mania and hypomania starts in mid-to-late adolescence. Moreover, clinically significant manic symptoms may occur even earlier, especially in children at familial risk. Lithium is the gold standard treatment for acute mania in adults, yet to our knowledge, there is no published systematic review assessing lithium treatment of mania in children or adolescents...
December 2017: International Journal of Bipolar Disorders
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