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Anti-mullerian hormone

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https://www.readbyqxmd.com/read/28094762/persistent-mullerian-duct-syndrome-with-transverse-testicular-ectopia-a-novel-amh-receptor-mutation
#1
Özlem Korkmaz, Samim Özen, Nurhan Özcan, Petek Bayındır, Sait Şen, Hüseyin Onay, Damla Gökşen, Ali Avanoğlu, Ferda Özkınay, Şükran Darcan
Persistent Mullerian duct syndrome is the result of either anti-Mullerian hormone (AMH) deficiency or AMH receptor resistance. A long tubular structure (testis/?) was palpated during the physical examination of a 13-month-old male patient who admitted because of bilateral undescended testes. Structures suggestive of ovaries, a uterus and fallopian tubes were observed during laparoscopic examination of the ectopic testis. AMHR2 gene sequence analysis performed wıth a preliminary diagnosis of AMH receptor resistance revealed a previously unreported homozygous c...
January 17, 2017: Journal of Clinical Research in Pediatric Endocrinology
https://www.readbyqxmd.com/read/28090459/anti-m%C3%A3-llerian-hormone-as-a-predictor-of-polycystic-ovary-syndrome-treated-with-clomiphene-citrate
#2
Andon Hestiantoro, Yuwono Sri Negoro, Yohana Afrita, Budi Wiweko, Kanadi Sumapradja, Muharam Natadisastra
OBJECTIVE: This study aimed to determine the threshold of anti-Müllerian hormone (AMH) as predictor of follicular growth failure in polycystic ovary syndrome (PCOS) patients treated with clomiphene citrate (CC). METHODS: Fifty female subjects with PCOS were recruited and divided into two groups based on successful and unsuccessful follicular growth. Related variables such as age, infertility duration, cigarette smoking, use of Moslem hijab, sunlight exposure, fiber intake, body mass index, waist circumference, AMH level, 25-hydroxy vitamin D level, and growth of dominant follicles were obtained, assessed, and statistically analyzed...
December 2016: Clinical and Experimental Reproductive Medicine
https://www.readbyqxmd.com/read/28081535/efficacy-and-safety-of-continuous-subcutaneous-infusion-of-recombinant-human-gonadotropins-for-congenital-micropenis-during-early-infancy%C3%A2
#3
Athanasia Stoupa, Dinane Samara-Boustani, Isabelle Flechtner, Graziella Pinto, Isabelle Jourdon, Laura González-Briceño, Maud Bidet, Kathleen Laborde, Didier Chevenne, Anne-Elodie Millischer, Henri Lottmann, Thomas Blanc, Yves Aigrain, Michel Polak, Jacques Beltrand
BACKGROUND: Early postnatal administration of gonadotropins to infants with congenital hypogonadotropic hypogonadism (CHH) can mimic minipuberty, thereby increasing penile growth. We assessed the effects of gonadotropin infusion on stretched penile length (SPL) and hormone levels in infants with congenital micropenis. METHODS: Single-center study including 6 males with micropenis in case of isolated CHH (n = 4), panhypopituitarism (n = 1), and partial androgen insensitivity syndrome (PAIS; n = 1)...
January 12, 2017: Hormone Research in Pædiatrics
https://www.readbyqxmd.com/read/28081480/does-the-addition-of-salpingectomy-or-fimbriectomy-to-hysterectomy-in-premenopausal-patients-compromise-ovarian-reserve-a-prospective-study
#4
Y Naaman, Y Hazan, M Gillor, G Marciano, R Bardenstein, Z Shoham, A Ben-Arie
OBJECTIVE: To evaluate changes in ovarian reserve in patients following hysterectomy, with or without bilateral salpingectomy or fimbriectomy. STUDY DESIGN: Open-label, prospective cohort trial of patients undergoing hysterectomy for benign uterine indications. Levels of follicle-stimulating hormone (FSH), anti-Müllerian hormone (AMH), and ultrasonic measures of peak systolic flow velocity/diastolic velocity (S/D) ratio and resistance index (RI) in the ovarian artery were taken from patients before and 6 weeks after hysterectomy, hysterectomy+salpingectomy or hysterectomy+fimbriectomy...
December 27, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/28066837/age-specific-nomograms-for-follicle-stimulating-hormone-and-anti-mullerian-hormone-a-pilot-study-in-ile-ife-nigeria
#5
Omoladun Temitope Okunola, Olusegun Kayode Ajenifuja, Morebise Olabisi Loto, Afolabi Salawu, Oluseyi Stephen Omitinde, Joel Akande, Elizabeth Oke
BACKGROUND: Assessment of ovarian reserve is one of the steps in the management of infertile couples. Follicle Stimulating hormone (FSH) and anti-Müllerian hormone (AMH) are commonly used ovarian reserve markers in Africa. However, there is paucity of age-specific reference values for FSH and AMH among the African population. OBJECTIVE: This study aimed at conducting a pilot study for generation of age-specific nomograms for FSH and AMH among fertile women in Ile-Ife, Nigeria...
December 2016: International Journal of Reproductive Biomedicine (Yazd, Iran)
https://www.readbyqxmd.com/read/28062641/melatonin-levels-in-follicular-fluid-as-markers-for-ivf-outcomes-and-predicting-ovarian-reserve
#6
Jing Tong, Shi-le Sheng, Yun Sun, Huihui Li, Wei-Ping Li, Cong Zhang, Zijiang Chen
Good-quality oocytes are critical for the success of in vitro fertilization (IVF), but, to date, there is no marker of ovarian reserve available that can accurately predict oocyte quality. Melatonin exerts its antioxidant actions as a strong radical scavenger that might affect oocyte quality directly, since it is the most potent antioxidant in follicular fluid. To investigate the precise role of endogenous melatonin in IVF outcomes, we recruited 61 women undergoing treatment cycles of IVF or intracytoplasmic sperm injection (ICSI) procedures and classified them into three groups according to their response to ovarian stimulation...
January 6, 2017: Reproduction: the Official Journal of the Society for the Study of Fertility
https://www.readbyqxmd.com/read/28050957/prediction-of-metaphase-ii-oocytes-according-to-different-serum-anti-m%C3%A3-llerian-hormone-amh-levels-in-antagonist-icsi-cycles
#7
Joyce B da Silva, Tatiana R Panaino, Maria A Tamm, Paloma Lira, Patricia C F Arêas, Ana C A Mancebo, Marcelo M de Souza, Roberto A Antunes, Maria do Carmo B de Souza
OBJECTIVE: This paper aims to assess a qualitative aspect of ovarian response in terms of metaphase II oocytes according to different serum Anti-Müllerian hormone levels in antagonist ICSI cycles. A prediction index might contribute to the individualization of care. METHODS: This observational study looked into 287 antagonist ICSI cycles carried out with patients treated in a single center between January of 2012 and January of 2016. Serum AMH and subgroup analyses were performed based on five AMH ranges (≤ 0...
December 1, 2016: JBRA Assisted Reproduction
https://www.readbyqxmd.com/read/28044970/-anti-m%C3%A3-llerian-hormone-a-new-regulator-of-pituitary-gonadotrope-cells-involvement-in-sexual-dimorphism-of-gonadotrope-activity-before-puberty
#8
Ghislaine Garrel, Chrystèle Racine, David L'Hôte, Chantal Denoyelle, Céline J Guigon, Nathalie di Clemente, Joëlle Cohen-Tannoudji
No abstract text is available yet for this article.
December 2016: Médecine Sciences: M/S
https://www.readbyqxmd.com/read/28043339/age-related-changes-in-transcriptional-abundance-and-circulating-levels-of-anti-mullerian-hormone-and-sertoli-cell-count-in-crossbred-and-zebu-bovine-males
#9
S K Rajak, A Kumaresan, N M Attupuram, S Chhillar, R K Baithalu, S Nayak, L Sreela, Raushan K Singh, U K Tripathi, T K Mohanty, Savita Yadav
Age-related changes in peripheral anti-Mullerian hormone (AMH) concentrations and transcriptional abundance of AMH gene in testicular tissue were studied in crossbred (Holstein Friesian × Tharparkar) and Zebu (Tharparkar) males. In both the breeds, basal AMH concentrations were estimated using ELISA method in blood plasma obtained from six males each at 1, 6, 12, 18, and 24 months age. After blood collection at respective ages, all the males were castrated and expression and immunolocalization of AMH was performed in the testicular tissue...
February 2017: Theriogenology
https://www.readbyqxmd.com/read/28004236/ghrelin-is-independently-associated-with-anti-mullerian-hormone-levels-in-obese-but-not-non-obese-women-with-polycystic-ovary-syndrome
#10
Margaret C Garin, Samantha F Butts, David B Sarwer, Kelly C Allison, Suneeta Senapati, Anuja Dokras
Ghrelin is an endogenous appetite stimulant that may have a role in ovarian function. Women with polycystic ovary syndrome have anovulation and frequently weight management issues; however the associations between ghrelin and hormonal markers in polycystic ovary syndrome have not been well studied. In order to characterize the association between total ghrelin levels and ovarian function and the possible modification of this relationship by obesity, we examined total ghrelin levels and anti-mullerian hormone, total testosterone, and insulin in obese and non-obese women with and without polycystic ovary syndrome...
December 21, 2016: Endocrine
https://www.readbyqxmd.com/read/27998701/anti-m%C3%A3-llerian-hormone-in-obese-adolescent-girls-with-polycystic-ovary-syndrome
#11
Joon Young Kim, Hala Tfayli, Sara F Michaliszyn, SoJung Lee, Alexis Nasr, Silva Arslanian
PURPOSE: Anti-Müllerian hormone (AMH) is proposed as a biomarker of polycystic ovary syndrome (PCOS). This study investigated: (1) AMH concentrations in obese adolescents with PCOS versus without PCOS; (2) the relationship of AMH to sex steroid hormones, adiposity, and insulin resistance; and (3) the optimal AMH value and the multivariable prediction model to determine PCOS in obese adolescents. METHODS: AMH levels were measured in 46 obese PCOS girls and 43 obese non-PCOS girls...
December 17, 2016: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
https://www.readbyqxmd.com/read/27993552/new-pcos-like-phenotype-in-older-infertile-women-of-likely-autoimmune-adrenal-etiology-with-high-amh-but-low-androgens
#12
Norbert Gleicher, Vitaly A Kushnir, Sarah K Darmon, Qi Wang, Lin Zhang, David F Albertini, David H Barad
How anti-Müllerian hormone (AMH) and testosterone (T) interrelate in infertile women is currently largely unknown. We, therefore, in a retrospective cohort study investigated how infertile women with high-AMH (AMH ≥75th quantile; n=144) and with normal-AMH (25th-75th quantile; n=313), stratified for low-T (total testosterone ≤19.0ng/dL), normal-T (19.0-29.0ng/dL) and high-T (>29.0ng/dL) phenotypically behaved. Patient age, follicle stimulating hormone (FSH), dehyroepiandrosterone (DHEA), DHEA sulphate (DHEAS), cortisol (C), adrenocorticotrophic hormone (ACTH), IVF outcomes, as well as inflammatory and immune panels were then compared between groups, with AMH and T as variables...
December 16, 2016: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/27990627/the-fertility-assessment-and-counselling-clinic-does-the-concept-work-a-prospective-two-year-follow-up-study-of-519-women
#13
Kathrine Birch Petersen, Thomas Maltesen, Julie L Forman, Randi Sylvest, Anja Pinborg, Elisabeth C Larsen, Kirsten T Macklon, Henriette S Nielsen, Helene W Hvidman, Anders Nyboe Andersen
INTRODUCTION: The Fertility Assessment and Counselling (FAC) Clinic was initiated to provide women information about their current fertility status to prevent infertility and smaller families than desired. The aim was to study the predictive value of a risk assessment score based on known fertility risk factors in terms of time to pregnancy. MATERIAL AND METHODS: Prospective cohort study of the first 570 women attending the FAC Clinic from 2011 to 2013 at Rigshospitalet, Denmark...
December 19, 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/27987358/relationship-between-anti-m%C3%A3-llerian-hormone-and-antral-follicle-count-across-the-menstrual-cycle-using-the-beckman-coulter-access-assay-in-comparison-with-gen-ii-manual-assay
#14
Julia Schiffner, Judith Roos, David Broomhead, Joseph van Helden, Erhard Godehardt, Daniel Fehr, Günter Freundl, Sarah Johnson, Christian Gnoth
BACKGROUND: The study aim was to validate Beckman Coulter's fully automated Access Immunoassay System (BC Access assay) for anti-Müllerian hormone (AMH) and compare it with Beckman Coulter's Modified Manual Generation II assay (BC Mod Gen II), with regard to cycle AMH fluctuations and antral follicle counts. METHODS: During one complete menstrual cycle, transvaginal ultrasound was performed on regularly menstruating women (n=39; 18-40years) every 2 days until the dominant ovarian follicle reached 16mm, then daily until observed ovulation; blood samples were collected throughout the cycle...
December 17, 2016: Clinical Chemistry and Laboratory Medicine: CCLM
https://www.readbyqxmd.com/read/27987339/evaluation-of-ovarian-reserve-using-anti-m%C3%A3-llerian-hormone-and-antral-follicle-count-in-sj%C3%A3-gren-s-syndrome-preliminary-study
#15
Savas Karakus, Ali Sahin, Yunus Durmaz, Huseyin Aydin, Caglar Yildiz, Ozlem Akkar, Mansur Dogan, Ahmet Cengiz, Meral Cetin, Ali Cetin
AIM: The aim of this study was to determine ovarian reserve status using anti-müllerian hormone (AMH) level and antral follicle count (AFC) in patients with Sjögren's syndrome (SS). METHODS: Twenty-four women with SS diagnosed according to the classification criteria proposed by the American-European Consensus Group and 25 healthy women as controls were enrolled in this study. Ovarian reserve was assessed on clinical findings, AFC, and serum AMH and reproductive hormone levels...
December 17, 2016: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/27978775/can-amh-levels-predict-the-need-for-increased-medication-during-ivf-icsi-in-pcos-women
#16
Ahmed Kamel, Wafaa Ramadan, Ahmed M Hussein, Sherif Dahab, Moutaz M Elsherbini, Yossra S Lasheen, Fouad Abu-Hamila
PURPOSE: To investigate the ability of anti-mullerian hormone (AMH) to predict the step up of human menopausal gonadotrophins (HMG) dose in women with polycystic ovarian syndrome (PCOS) undergoing IVF/ICSI cycles. METHODS: AMH was drawn before ovulation induction in 976 PCOS women scheduled for IVF/ICSI. After all cycles ended, a ROC curve analysis was done to investigate the ability of AMH to predict step up of the HMG. RESULTS: The area under the curve was 0...
December 15, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27976974/predictive-values-of-anti-m%C3%A3-llerian-hormone-antral-follicle-count-and-ovarian-response-prediction-index-orpi-for-assisted-reproductive-technology-outcomes
#17
Mahnaz Ashrafi, Mandana Hemat, Arezoo Arabipoor, Reza Salman Yazdi, Akram Bahman-Abadi, Rezvaneh Cheraghi
This prospective study was performed from June 2012 to June 2014 at Royan Institute to compare the predictive values of serum anti-müllerian hormone (AMH), antral follicle count (AFC) and ovarian response prediction index (ORPI) ([AFC × AMH]/age) for in vitro fertilisation/intracytoplasmic sperm injection (IVF/ICSI) cycle outcomes. Five hundred and fifty women included in the study with male factor and unexplained infertility were the first candidates for IVF/ICSI cycles. Serum AMH level was measured by a commercial ELISA kit and AFC was calculated by a transvaginal ultrasonography on day 2-3 of the menstrual cycle before starting ovarian stimulation...
December 15, 2016: Journal of Obstetrics and Gynaecology: the Journal of the Institute of Obstetrics and Gynaecology
https://www.readbyqxmd.com/read/27940394/assessment-of-ovarian-reserve-after-hysterectomy-laparoscopic-vs-non-laparoscopic-surgery
#18
Hye-Yon Cho, Sung Taek Park, Min Sun Kyung, Sung-Ho Park
OBJECTIVES: To evaluate changes of ovarian reserve after hysterectomy by comparing serum anti-Mullerian hormone (AMH) levels following laparoscopic hysterectomy (LH) to those of non-laparoscopic hysterectomy (non-LH). METHODS: Prospectively, serum AMH levels were measured pre-operatively (AMH0), 7days (AMH1), 2 months (AMH2), and 6 months (AMH3) after LH (total laparoscopic hysterectomy or laparoscopy-assisted vaginal hysterectomy) and non-LH (vaginal hysterectomy or abdominal hysterectomy) in 91 premenopausal women (LH=60, non-LH=31)...
December 5, 2016: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/27940159/dmrt1-is-necessary-for-male-sexual-development-in-zebrafish
#19
Kaitlyn A Webster, Ursula Schach, Angel Ordaz, Jocelyn S Steinfeld, Bruce W Draper, Kellee R Siegfried
The dmrt1 (doublesex and mab-3 related transcription factor 1) gene is a key regulator of sex determination and/or gonadal sex differentiation across metazoan animals. This is unusual given that sex determination genes are typically not well conserved. The mechanisms by which zebrafish sex is determined have remained elusive due to the lack of sex chromosomes and the complex polygenic nature of sex determination in domesticated strains. To investigate the role of dmrt1 in zebrafish sex determination and gonad development, we isolated mutations disrupting this gene...
December 8, 2016: Developmental Biology
https://www.readbyqxmd.com/read/27928855/impact-of-laparoscopic-ovarian-detorsion-on-ovarian-reserve
#20
Cenk Yasa, Ozlem Dural, Ercan Bastu, Masallah Zorlu, Omer Demir, Funda Gungor Ugurlucan
AIM: The aim of this study was to evaluate ovarian reserve after laparoscopic ovarian detorsion in patients with ovarian torsion. METHODS: From February 2014 to September 2015, a total of 11 patients with ovarian torsion underwent laparoscopic detorsion. These 11 patients were eligible for study, and ovarian reserve was assessed on serum anti-Müllerian hormone (AMH) and by antral follicle count preoperatively, and in postoperative months 1 and 3. RESULTS: Mean patient age was 25...
December 8, 2016: Journal of Obstetrics and Gynaecology Research
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