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https://www.readbyqxmd.com/read/28918391/genetic-polymorphisms-associated-with-the-risk-of-concussion-in-1056-college-athletes-a-multicentre-prospective-cohort-study
#1
Thomas Roland Terrell, Ruth Abramson, Jeffery T Barth, Ellen Bennett, Robert C Cantu, Richard Sloane, Daniel T Laskowitz, David M Erlanger, Douglas McKeag, Gregory Nichols, Verle Valentine, Leslie Galloway
BACKGROUND/AIM: To evaluate the association of genetic polymorphisms APOE, APOE G-219T promoter, microtubule associated protein(MAPT)/tau exon 6 Ser(53)Pro, MAPT/tau Hist(47)Tyr, IL-6572 G/C and IL-6R(Asp)358(Ala) with the risk of concussion in college athletes. METHODS: A 23-centre prospective cohort study of 1056 college athletes with genotyping was completed between August 2003 and December 2012. All athletes completed baseline medical and concussion questionnaires, and post-concussion data were collected for athletes with a documented concussion...
September 16, 2017: British Journal of Sports Medicine
https://www.readbyqxmd.com/read/28917118/calibration-of-the-comprehensive-ndha-n2o-dynamics-model-for-nitrifier-enriched-biomass-using-targeted-respirometric-assays
#2
Carlos Domingo-Félez, Maria Calderó-Pascual, Gürkan Sin, Benedek G Plósz, Barth F Smets
The NDHA model comprehensively describes nitrous oxide (N2O) producing pathways by both autotrophic ammonium oxidizing and heterotrophic bacteria. The model was calibrated via a set of targeted extant respirometric assays using enriched nitrifying biomass from a lab-scale reactor. Biomass response to ammonium, hydroxylamine, nitrite and N2O additions under aerobic and anaerobic conditions were tracked with continuous measurement of dissolved oxygen (DO) and N2O. The sequential addition of substrate pulses allowed the isolation of oxygen-consuming processes...
September 7, 2017: Water Research
https://www.readbyqxmd.com/read/28902769/factors-associated-with-financial-relationships-between-spine-surgeons-and-industry-an-analysis-of-the-open-payments-database
#3
Joseph A Weiner, Ralph W Cook, Sohaib Hashmi, Michael S Schallmo, Danielle S Chun, Kathryn A Barth, Sameer K Singh, Alpesh A Patel, Wellington K Hsu
STUDY DESIGN: A retrospective review of Centers for Medicare and Medicaid Services Database. OBJECTIVE: Utilizing Open Payments data, we aimed to determine the prevalence of industry payments to orthopedic and neurospine surgeons, report the magnitude of those relationships, and help outline the surgeon demographic factors associated with industry relationships. SUMMARY OF BACKGROUND DATA: Previous Open Payments data revealed that orthopedic surgeons receive the highest value of industry payments...
September 15, 2017: Spine
https://www.readbyqxmd.com/read/28898286/structural-investigation-of-c6-36-and-vero-cell-cultures-infected-with-a-brazilian-zika-virus
#4
Debora Ferreira Barreto-Vieira, Fernanda Cunha Jácome, Marcos Alexandre Nunes da Silva, Gabriela Cardoso Caldas, Ana Maria Bispo de Filippis, Patrícia Carvalho de Sequeira, Elen Mello de Souza, Audrien Alves Andrade, Pedro Paulo de Abreu Manso, Gisela Freitas Trindade, Sheila Maria Barbosa Lima, Ortrud Monika Barth
Zika virus (ZIKV) is a member of the flavivirus genus, and its genome is approximately 10.8 kilobases of positive-strand RNA enclosed in a capsid and surrounded by a membrane. Studies on the replication dynamics of ZIKV are scarce, which limits the development of antiviral agents and vaccines directed against ZIKV. In this study, Aedes albopictus mosquito lineage cells (C6/36 cells) and African green monkey kidney epithelial cells (Vero cells) were inoculated with a ZIKV sample isolated from a Brazilian patient, and the infection was characterized by immunofluorescence staining, phase contrast light microscopy, transmission electron microscopy and real-time RT-PCR...
2017: PloS One
https://www.readbyqxmd.com/read/28895427/the-impact-of-self-perceived-limitations-stigma-and-sense-of-coherence-on-quality-of-life-in-multiple-sclerosis-patients-results-of-a-cross-sectional-study
#5
Feddrik Broersma, Barth Oeseburg, Jacob Dijkstra, Klaske Wynia
OBJECTIVE: To examine the impact of perceived limitations, stigma and sense of coherence on quality of life in multiple sclerosis patients. DESIGN: Cross-sectional survey. SETTING: Department of Neurology, University Medical Center Groningen, the Netherlands. SUBJECTS: Multiple sclerosis patients. MAIN MEASURES: World Health Organization Quality of Life - abbreviated version, Stigma Scale for Chronic Illness, Sense of Coherence Scale, background and disease-related questions...
September 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28886239/terminal-alkyne-coupling-on-a-corrugated-noble-metal-surface-from-controlled-precursor-alignment-to-selective-reactions
#6
Tao Lin, Liding Zhang, Jonas Björk, Zhi Chen, Mario Ruben, Johannes V Barth, Florian Klappenberger
Surface-templated covalent coupling of organic precursors currently emerges as a promising route to the atom-precise fabrication of low-dimensional carbon materials. Here, we investigate the adsorption and the coupling reactions of 4,4''-diethynyl-1,1':4',1''- terphenyl on Au(110) under ultra-high vacuum conditions by using scanning tunneling microscopy combined with density functional theory and kinetic Monte Carlo calculations. Temperature treatment induces both 1,2,4 asymmetric cyclotrimerization and homo-coupling, resulting in various reaction products including a previously- unreported, surface-templated H-shaped pentamer...
September 8, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28884356/diagnostic-value-of-mri-based-3d-texture-analysis-for-tissue-characterisation-and-discrimination-of-low-grade-chondrosarcoma-from-enchondroma-a-pilot-study
#7
Catharina S Lisson, Christoph G Lisson, Kerstin Flosdorf, Regine Mayer-Steinacker, Markus Schultheiss, Alexandra von Baer, Thomas F E Barth, Ambros J Beer, Matthias Baumhauer, Reinhard Meier, Meinrad Beer, Stefan A Schmidt
OBJECTIVES: To explore the diagnostic value of MRI-based 3D texture analysis to identify texture features that can be used for discrimination of low-grade chondrosarcoma from enchondroma. METHODS: Eleven patients with low-grade chondrosarcoma and 11 patients with enchondroma were retrospectively evaluated. Texture analysis was performed using mint Lesion: Kurtosis, entropy, skewness, mean of positive pixels (MPP) and uniformity of positive pixel distribution (UPP) were obtained in four MRI sequences and correlated with histopathology...
September 7, 2017: European Radiology
https://www.readbyqxmd.com/read/28882077/review-the-potential-impact-of-surface-crystalline-states-of-titanium-for-biomedical-applications
#8
Julien Barthes, Sait Ciftci, Florian Ponzio, Helena Knopf-Marques, Liza Pelyhe, Alexandru Gudima, Imre Kientzl, Eszter Bognár, Miklós Weszl, Julia Kzhyshkowska, Nihal Engin Vrana
In many biomedical applications, titanium forms an interface with tissues, which is crucial to ensure its long-term stability and safety. In order to exert control over this process, titanium implants have been treated with various methods that induce physicochemical changes at nano and microscales. In the past 20 years, most of the studies have been conducted to see the effect of topographical and physicochemical changes of titanium surface after surface treatments on cells behavior and bacteria adhesion...
September 7, 2017: Critical Reviews in Biotechnology
https://www.readbyqxmd.com/read/28873347/outcomes-of-capsulolabral-reconstruction-for-posterior-shoulder-instability
#9
Andrieu Kevin, Barth Johannes, Saffarini Mo, Clavert Philippe, Godenèche Arnaud, Mansat Pierre
Surgical treatment of isolated posterior shoulder instability-a rare and often misdiagnosed condition-is controversial because of poor outcomes.Failure of physical therapy in symptomatic young athletes requires capsulolabral reconstruction or bone block procedures. The goal of this study was to report the outcomes of patients who have undergone surgical capsulolabral reconstruction and to look for risk factors that contribute to failure of this procedure.We analyzed the outcomes of 101 patients who underwent capsulolabral reconstruction: 83 included retrospectively, 18 included prospectively...
September 2, 2017: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/28872822/corrugation-in-the-weakly-interacting-hexagonal-bn-cu-111-system-structure-determination-by-combining-noncontact-atomic-force-microscopy-and-x-ray-standing-waves
#10
Martin Schwarz, Alexander Riss, Manuela Garnica, Jacob Ducke, Peter S Deimel, David A Duncan, Pardeep Kumar Thakur, Tien-Lin Lee, Ari Paavo Seitsonen, Johannes V Barth, Francesco Allegretti, Willi Auwärter
Atomically thin hexagonal boron nitride (h-BN) layers on metallic supports represent a promising platform for the selective adsorption of atoms, clusters, and molecular nanostructures. Specifically, scanning tunneling microscopy (STM) studies revealed an electronic corrugation of h-BN/Cu(111), guiding the self-assembly of molecules and their energy level alignment. A detailed characterization of the h-BN/Cu(111) interface including the spacing between the h-BN sheet and its support-elusive to STM measurements-is crucial to rationalize the interfacial interactions within these systems...
September 5, 2017: ACS Nano
https://www.readbyqxmd.com/read/28855095/lipids-of-dietzia-sp-a14101-part-i-a-study-of-the-production-dynamics-of-surface-active-compounds
#11
Ina Hvidsten, Svein Are Mjøs, Bjarte Holmelid, Gunhild Bødtker, Tanja Barth
Dietzia sp. A14101 belonging to the genus Dietzia (Gram-positive bacteria, Actinomycetes, high G+C content of DNA) was isolated from an oil reservoir model column inoculated with oil-field bacteria (Bødtker et al., 2009). Low interfacial tension (IFT) values were obtained by studying intact strain cells grown on water-immiscible hydrocarbons (HC) (Kowalewski et al. (2004), Kowalewski et al. (2005). Further investigations showed that the adaptation mechanism of Dietzia sp. A14101 to toxic water-immiscible HC involved changes both on the level of fatty acids content and in the physical properties of the cellular surface (development of the negative cellular surface charge and an increased in hydrophobicity) (Hvidsten et al...
August 31, 2017: Chemistry and Physics of Lipids
https://www.readbyqxmd.com/read/28845476/opioid-prescription-drug-use-and-expenditures-in-us-outpatient-physician-offices-evidence-from-two-nationally-representative-surveys
#12
Zaina P Qureshi, M Rifat Haider, Rosa Rodriguez-Monguio, Nikki R Wooten, Ruslan V Nikitin, Sarah Ball, Kelly Barth, Ronit Elk, Ronnie Horner, Charles Bennett
BACKGROUND: Opioids are widely prescribed for their analgesic properties. Chronic opioid use is a persistent problem in the US. Nevertheless, little is known about its prescribing and utilization patterns and overall expenditures. OBJECTIVE: This study examined secular trends in opioid prescription drug utilization and expenditures, along with factors associated with opioid prescription drug use in US physician offices. METHODS: National Ambulatory Medical Care Survey (NAMCS) and Medical Expenditure Panel Survey (MEPS) data (2006-2010), both nationally representative surveys, were used to assess the trend, predictors of opioid prescription among US adults (more than 18 years) and the opioid-associated expenditures as a whole and borne by the patients in outpatient settings...
2017: Cancer Ther Oncol Int J
https://www.readbyqxmd.com/read/28837792/lipids-of-dietzia-sp-a14101-part-ii-a-study-of-the-dynamics-of-the-release-of-surface-active-compounds-by-dietzia-sp-a14101-into-the-medium
#13
Ina Hvidsten, Svein Are Mjøs, Gunhild Bødtker, Tanja Barth
Dietzia sp. A14101 isolated from an oil reservoir model column was found to induce a strong decrease of the interfacial tension (IFT) in hydrocarbon-water mixtures in the presence of the intact bacterial cells (Kowalewski et al., 2005). The strain was shown to be able to degrade a wide range of hydrocarbon substrates (Bødtker et al., 2009). Further studies showed that the surface-active compounds tentatively identified as glycolipids were produced by Dietzia sp. A14101 on non- and water-immiscible -hydrocarbon substrates, Part I (Hvidsten et al...
August 31, 2017: Chemistry and Physics of Lipids
https://www.readbyqxmd.com/read/28837512/the-management-of-acute-pancreatitis-in-the-pediatric-population-a-clinical-report-from-the-naspghan-pancreas-committee
#14
Maisam Abu-El-Haija, Soma Kumar, J Antonio Quiros, Keshawadhana Balakrishnan, Bradley Barth, Samuel Bitton, John F Eisses, Elsie Jazmin Foglio, Victor Fox, Denease Francis, A Jay Freeman, Tanja Gonska, Amit S Grover, Sohail Z Husain, Rakesh Kumar, Sameer Lapsia, Tom Lin, Quin Y Liu, Asim Maqbool, Zachary M Sellers, Flora Szabo, Aliye Uc, Steven L Werlin, Veronique D Morinville
BACKGROUND: While the incidence of acute pancreatitis (AP) in children is increasing, management recommendations rely on adult published guidelines. Pediatric-specific recommendations are needed. METHODS: The NASPGHAN Pancreas committee performed a MEDLINE review using several pre-selected key terms relating to management considerations in adult and pediatric AP. The literature was summarized, quality of evidence reviewed, and statements of recommendations developed...
August 23, 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28822639/level-of-the-subscapularis-split-during-arthroscopic-latarjet
#15
Alexandre Lädermann, Patrick J Denard, Paolo Arrigoni, Pablo Narbona, Stephen S Burkhart, Johannes Barth
PURPOSE: To determine the location of the subscapularis split during arthroscopic Latarjet created by an inside-out technique passing a switching stick from the posterior portal across the glenohumeral joint. METHODS: An inside-out technique was used to arthroscopically create a subscapularis split in 20 fresh-frozen human cadaveric shoulders. The distance between the exit point of the switching stick and the upper border of the subscapularis and the anterior circumflex vessels was measured arthroscopically and after open dissection...
August 16, 2017: Arthroscopy: the Journal of Arthroscopic & related Surgery
https://www.readbyqxmd.com/read/28820547/incidence-and-clinical-impact-of-cerebral-lesions-after-the-mitraclip%C3%A3-%C3%A2-procedure
#16
Sebastian Barth, Karsten Hamm, Stefan Fodor, Wilko Reents, Sebastian Kerber, Philipp Halbfass, Martina B Hautmann, Bernhard Schieffer, Hassan Soda
BACKGROUND: Clinically silent brain injury detected with cerebral magnetic resonance imaging (MRI) is well known after various cardiovascular interventions. Thus far, only one study has examined the periprocedural risk of cerebral ischemic events in patients undergoing percutaneous mitral valve reconstruction. The study aim was to examine the incidence and clinical impact of cerebral embolic events in patients undergoing percutaneous mitral valve reconstruction using the MitraClip® system...
March 2017: Journal of Heart Valve Disease
https://www.readbyqxmd.com/read/28819367/short-term-effectiveness-of-inpatient-cancer-rehabilitation-a-longitudinal-controlled-cohort-study
#17
Maria Ture, Felix Angst, André Aeschlimann, Christoph Renner, Ulrich Schnyder, Nic Zerkiebel, Josef Perseus, Jürgen Barth, Marius Bredell, Chantal Martin Soelch, Heinrich Walt, Josef Jenewein
Background: Inpatient rehabilitation for cancer patients has been demonstrated to improve patients' health related quality of life (HRQoL) effectively. The purpose of this study was to compare changes in general health and HRQoL of cancer patients who were referred to inpatient rehabilitation (IR) with those in two control groups who underwent outpatient management either with advice for inpatient rehabilitation (A(+)) or without (A(-)). Methods: In this naturalistic, longitudinal, controlled cohort study, changes in general health and HRQoL were assessed at either discharge of acute hospital or start of rehabilitation (baseline) and at the follow-up 3 weeks later or end of rehabilitation...
2017: Journal of Cancer
https://www.readbyqxmd.com/read/28818984/pseudo-reference-regions-for-glial-imaging-with-11-c-pbr28-investigation-in-two-clinical-cohorts
#18
Daniel Strakis Albrecht, Marc David Normandin, Sergey Shcherbinin, Dustin W Wooten, Adam J Schwarz, Nicole R Zurcher, Vanessa N Barth, Nicolas J Guehl, Oluwaseun Johnson-Akeju, Nazem Atassi, Mattia Veronese, Federico Turkheimer, Jacob M Hooker, Marco Luciano Loggia
The translocator protein (TSPO) is a commonly used imaging target to investigate neuroinflammation. While TSPO imaging demonstrates great promise, its signal exhibits substantial interindividual variability, which needs to be accounted for to uncover group effects that are truly reflective of neuroimmune activation. Recent evidence suggests that relative metrics computed using pseudo-reference approaches can minimize within-group variability, and increase sensitivity to detect physiologically meaningful group differences...
August 17, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28818025/improvement-of-transition-metal-modified-activated-carbon-regeneration-by-h2o2-promoted-catalytic-wet-air-oxidation
#19
Imane Benhamed, Laurie Barthe, Rachid Kessas, Henri Delmas, Carine Julcour
Oxidative regeneration of activated carbon exhausted with phenolic compounds is still a challenging issue due to the frequent porosity loss. Addition of low H2O2 amount is investigated as a way to promote catalytic wet air oxidation (CWAO) of adsorbed pollutants and thereby to recover absorbent properties. Commercial activated carbon and transition metal (iron or copper) modified counterparts are tested in repeated adsorption / batch peroxide-promoted CWAO of phenol. Cycles are operated in both fixed bed and slurry reactors to vary the initial pollutant distribution in between the two phases...
August 18, 2017: Environmental Technology
https://www.readbyqxmd.com/read/28811149/three-center-feasibility-of-lung-clearance-index-in-infants-and-preschool-children-with-cystic-fibrosis-and-other-lung-diseases
#20
Mirjam Stahl, Simon Y Graeber, Cornelia Joachim, Sandra Barth, Isabell Ricklefs, Gesa Diekmann, Matthias V Kopp, Lutz Naehrlich, Marcus A Mall
BACKGROUND: Lung clearance index (LCI) detects early ventilation inhomogeneity and has been suggested as sensitive endpoint in multicenter intervention trials in infants and preschoolers with cystic fibrosis (CF). However, the feasibility of multicenter LCI in this age group has not been determined. We, therefore, investigated the feasibility of LCI in infants and preschoolers with and without CF in a three-center setting. METHODS: Following central training, standardized SF6-MBW measurements were performed in 73 sedated children (10 controls, 49 with CF and 14 with other lung diseases), mean age 2...
August 12, 2017: Journal of Cystic Fibrosis: Official Journal of the European Cystic Fibrosis Society
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