keyword
MENU ▼
Read by QxMD icon Read
search

Animal law

keyword
https://www.readbyqxmd.com/read/29052384/-research-progress-of-serum-pharmacochemistry-of-traditional-chinese-medicine
#1
REVIEW
Fei-Xiang Ma, Pei-Feng Xue, Yuan-Yuan Wang, Yi-Nuo Wang, Shu-Yuan Xue
Serum pharmacochemistry of traditional Chinese medicine(TCM) is an effective method to rapidly screen the effective substances and reveal the compatibility law of compound by identification and analysis of constituents migrating to blood after oral administration. In the last two decades, it has been universally accepted and widely applied in the field. With the cross-fusion with other disciplines, such as serum pharmacology, pharmacokinetics, metabolomics, network pharmacology and systems biology, serum pharmacochemistry shows comprehensive superiority in explaining drug changes in vivo and in vitro, interactions between drugs, interactions between drug and body, which coincides with the complexity of TCM compatibility, multi-components, multi-targets and multi-mechanisms...
April 2017: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/29046579/a-general-scaling-law-reveals-why-the-largest-animals-are-not-the-fastest
#2
Myriam R Hirt, Walter Jetz, Björn C Rall, Ulrich Brose
Speed is the fundamental constraint on animal movement, yet there is no general consensus on the determinants of maximum speed itself. Here, we provide a general scaling model of maximum speed with body mass, which holds across locomotion modes, ecosystem types and taxonomic groups. In contrast to traditional power-law scaling, we predict a hump-shaped relationship resulting from a finite acceleration time for animals, which explains why the largest animals are not the fastest. This model is strongly supported by extensive empirical data (474 species, with body masses ranging from 30 μg to 100 tonnes) from terrestrial as well as aquatic ecosystems...
August 2017: Nature ecology & evolution
https://www.readbyqxmd.com/read/29045015/the-small-molecule-mertk-inhibitor-unc2025-decreases-platelet-activation-and-prevents-thrombosis
#3
Brian R Branchford, Timothy J Stalker, Luke Law, Gilbert Acevedo, Susan Sather, Christine Brzezinski, Katina M Wilson, Katherine Minson, Alisa B Lee-Sherick, Pavel Davizon-Castillo, Christopher Ng, Weihe Zhang, Keith B Neeves, Steven R Lentz, Xiaodong Wang, Stephen V Frye, H Shelton Earp, Deborah DeRyckere, Lawrence F Brass, Douglas K Graham, Jorge A Di Paola
BACKGROUND: Gas6 signals through the TAM (TYRO-3, AXL, MERTK) receptor family mediating platelet activation and thrombus formation via activation of the aggregate-stabilizing αIIb β3 integrin. OBJECTIVE: Here we describe anti-thrombotic effects mediated by UNC2025, a small molecule MERTK tyrosine kinase inhibitor. METHODS: MERTK phosphorylation and downstream signaling were assessed by immunoblot. Light transmission aggregometry, flow cytometry, and microfluidic analysis were used to evaluate the impact of MERTK inhibition on platelet activation and stability of aggregate formation in vitro...
October 17, 2017: Journal of Thrombosis and Haemostasis: JTH
https://www.readbyqxmd.com/read/29044369/law-as-a-fixture-between-the-one-health-interfaces-of-emerging-diseases
#4
Alexandra L Phelan, Lawrence O Gostin
A One Health approach calls for multisectoral and multi-institutional cooperation and partnership across the interfaces of human, animal and ecosystem health risks. Without strong governance, these interfaces risk detaching, leaving gaps in capacities to prevent, detect and respond to emerging and persisting public health threats. As a crucial component of governance, law can act as the fixture between interfaces. We examine some of the many forms and foci of law and propose that the process of law-making, implementation and evaluation can provide a benefit for strengthening law as a fixture between One Health interfaces...
June 1, 2017: Transactions of the Royal Society of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29040049/recent-trends-in-common-chemical-feed-and-food-contaminants-in-israel
#5
J A Shimshoni, Y Chen, E Sobol, I Maz, S Barel
In February 2014 a new law was approved by the Israeli parliament, namely the Control of Animal Feed Law. The law intends to regulate the production and marketing of animal feed. In preparation for the law's implementation in 2017, we have assessed the current feed and food safety challenges in Israel in recent years in association with the presence of common undesirable contaminants in various common feed and food commodities. Tight collaboration between regulatory authorities and fee/food industry, enhanced feed and food quality monitoring, transparency of survey results and readily accessible and reliable information for the public about health hazards of chemical contaminants, will guarantee the safety and quality of food and feed...
October 17, 2017: Journal of Environmental Science and Health. Part C, Environmental Carcinogenesis & Ecotoxicology Reviews
https://www.readbyqxmd.com/read/29027681/the-drivers-of-sea-lice-management-policies-and-how-best-to-integrate-them-into-a-risk-management-strategy-an-ecosystem-approach-to-sea-lice-management
#6
D Jackson, O Moberg, E M Stenevik Djupevåg, F Kane, H Hareide
The control of sea lice infestations on cultivated Atlantic salmon is a major issue in many regions of the world. The numerous drivers which shape the priorities and objectives of the control strategies vary for different regions/jurisdictions. These range from the animal welfare and economic priorities of the producers, to the mitigation of any potential impacts on wild stocks. Veterinary ethics, environmental impacts of therapeutants, and impacts for organic certification of the produce are, amongst others, additional sets of factors which should be considered...
October 13, 2017: Journal of Fish Diseases
https://www.readbyqxmd.com/read/28991316/-epidemiological-characterization-of-bites-on-people-as-emergency-care-record-province-of-los-andes-chile
#7
Vania Villagra, Dante Cáceres, Sergio Alvarado, Elizabeth Salinas, M Loreto Caldera, Erick Lucero, Paola Viviani, Marisa Torres
BACKGROUND: Bites constitute a public health problem worldwide. AIM: To characterize epidemiologically bites by animals happened in the province of Los Andes (2005-2007). METHOD: Descriptive, retrospective epidemiological study. Studied variables: Bitten person (BP), accident by bite, biting animal and bite. It was not feasible to obtain more updated information by law of patient protection. RESULTS: 2,360 BP were assisted in the emergency unit of San Juan de Dios Hospital and Rio Blanco clinic...
June 2017: Revista Chilena de Infectología: órgano Oficial de la Sociedad Chilena de Infectología
https://www.readbyqxmd.com/read/28972973/the-evolutionary-origins-of-l%C3%A3-vy-walk-foraging
#8
Marina E Wosniack, Marcos C Santos, Ernesto P Raposo, Gandhi M Viswanathan, Marcos G E da Luz
We study through a reaction-diffusion algorithm the influence of landscape diversity on the efficiency of search dynamics. Remarkably, the identical optimal search strategy arises in a wide variety of environments, provided the target density is sparse and the searcher's information is restricted to its close vicinity. Our results strongly impact the current debate on the emergentist vs. evolutionary origins of animal foraging. The inherent character of the optimal solution (i.e., independent on the landscape for the broad scenarios assumed here) suggests an interpretation favoring the evolutionary view, as originally implied by the Lévy flight foraging hypothesis...
October 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/28970347/the-metabolic-costs-of-sexual-signalling-in-the-chirping-katydid-plangia-graminea-serville-orthoptera-tettigoniidae-are-context-dependent-cumulative-costs-add-up-fast
#9
Marcé Doubell, Paul B C Grant, Nanike Esterhuizen, Corinna S Bazelet, Pia Addison, John S Terblanche
Katydids produce acoustic signals via stridulation which they use to attract conspecific females for mating. However, direct estimates of the metabolic costs of calling to date have produced diverse cost estimates and are limited to only a handful of insect species. In this study, we therefore investigated the metabolic cost of calling in a unstudied sub-Saharan katydid, Plangia graminea Using wild-caught animals, we measured katydid metabolic rate using standard flow-through respirometry while simultaneously recording the number of calls produced...
October 2, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28967368/is-cannabis-an-effective-treatment-for-joint-pain
#10
REVIEW
Richard J Miller, Rachel E Miller
Cannabis has been used to treat pain for thousands of years. However, since the early part of the 20th century, laws restricting cannabis use have limited its evaluation using modern scientific criteria. Over the last decade, the situation has started to change because of the increased availability of cannabis in the United States for either medical or recreational purposes, making it important to provide the public with accurate information as to the effectiveness of the drug for joint pain among other indications...
September 2017: Clinical and Experimental Rheumatology
https://www.readbyqxmd.com/read/28966570/effects-of-environmental-enrichment-on-doublecortin-and-bdnf-expression-along-the-dorso-ventral-axis-of-the-dentate-gyrus
#11
Fabio Gualtieri, Catherine Brégère, Grace C Laws, Elena A Armstrong, Nicholas J Wylie, Theo T Moxham, Raphael Guzman, Timothy Boswell, Tom V Smulders
Adult hippocampal neurogenesis (AHN) in the dentate gyrus is known to respond to environmental enrichment, chronic stress, and many other factors. The function of AHN may vary across the septo-temporal axis of the hippocampus, as different subdivisions are responsible for different functions. The dorsal pole regulates cognitive-related behaviors, while the ventral pole mediates mood-related responses through the hypothalamic-pituitary-adrenal (HPA) axis. In this study, we investigate different methods of quantifying the effect of environmental enrichment on AHN in the dorsal and ventral parts of the dentate gyrus (dDG and vDG)...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28963043/spontaneously-hypertensive-shr-rats-choose-more-impulsively-than-wistar-kyoto-wky-rats-on-a-delay-discounting-task
#12
Carlos F Aparicio, Paul J Hennigan, Laurel J Mulligan, Benigno Alonso-Alvarez
Indications of Attention Deficit Hyperactivity Disorder (ADHD) in the spontaneously hypertensive rat (SHR) are not consistent across different tests of impulsivity, questioning the SHR's validity as a rodent model of ADHD. This study used a concurrent-chains procedure to examine possible differences in impulsive choice between SHRs and control-normotensive Wistar Kyoto (WKY) rats. The aim was to extend the generality of findings showing regularities between the hyperbolic-decay model and the generalized matching law fitting delay discounting data from nonhuman animals...
September 26, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28949714/pressure-dependent-friction-on-granular-slopes-close-to-avalanche
#13
Jérôme Crassous, Antoine Humeau, Samuel Boury, Jérôme Casas
We investigate the sliding of objects on an inclined granular surface close to the avalanche threshold. Our experiments show that the stability is driven by the surface deformations. Heavy objects generate footprintlike deformations which stabilize the objects on the slopes. Light objects do not disturb the sandy surfaces and are also stable. For intermediate weights, the deformations of the surface generate a sliding of the objects. The solid friction coefficient does not follow the Amontons-Coulomb laws, but is found minimal for a characteristic pressure...
August 4, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28940809/effects-of-age-and-sex-ratios-on-offspring-recruitment-rates-in-translocated-black-rhinoceros
#14
Jay V Gedir, Peter R Law, Pierre du Preez, Wayne L Linklater
Success of animal translocations depends on improving post-release demographic rates toward establishment and subsequent growth of released populations. Short-term metrics for evaluating translocation success and its drivers, like post-release survival and fecundity, are unlikely to represent longer-term outcomes. We used information theory to investigate 25 years of black rhinoceros (Diceros bicornis) translocations using the offspring recruitment rate (ORR) of translocated females - a metric integrating survival, fecundity and offspring recruitment at sexual maturity - to detect determinants of success...
September 22, 2017: Conservation Biology: the Journal of the Society for Conservation Biology
https://www.readbyqxmd.com/read/28933130/-research-progress-on-breeding-standard-of-medicinal-animals-and-discussion-on-several-key-problems
#15
Yi-Quan Zhou, Xian-You Qu, Guang Yang, Jun-de Li, Yan Su, Ying Li
Medicinal animal breeding standards is regarded as the law to normalize relevant production that can guarantee the quality of traditional Chinese medicine of animal category. The article summarized the medicinal animal resources in our country and the present condition of medicinal animal breeding standards. It considered the current animal breeding standards system was in adequate, not only the quantity of breeding standards, the standard content and index were also uncomprehensive, which is not conducive to the scientific and orderly development and utilization of medicinal animal resources...
December 2016: Zhongguo Zhong Yao za Zhi, Zhongguo Zhongyao Zazhi, China Journal of Chinese Materia Medica
https://www.readbyqxmd.com/read/28915668/nsc30049-inhibits-chk1-pathway-in-5-fu-resistant-crc-bulk-and-stem-cell-populations
#16
Satya Narayan, Aruna S Jaiswal, Ritika Sharma, Akbar Nawab, Lizette Vila Duckworth, Brian K Law, Maria Zajac-Kaye, Thomas J George, Jay Sharma, Arun K Sharma, Robert A Hromas
The 5-fluorouracil (5-FU) treatment induces DNA damage and stalling of DNA replication forks. These stalled replication forks then collapse to form one sided double-strand breaks, leading to apoptosis. However, colorectal cancer (CRC) stem cells rapidly repair the stalled/collapsed replication forks and overcome treatment effects. Recent evidence suggests a critical role of checkpoint kinase 1 (Chk1) in preventing the replicative stress. Therefore, Chk1 kinase has been a target for developing mono or combination therapeutic agents...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28892929/connective-tissue-growth-factor-transgenic-mouse-develops-cardiac-hypertrophy-lean-body-mass-and-alopecia
#17
Edem Nuglozeh
INTRODUCTION: Connective Tissue Growth Factor (CTGF/CCN2) is one of the six members of cysteine-rich, heparin-binding proteins, secreted as modular protein and recognised to play a major function in cell processes such as adhesion, migration, proliferation and differentiation as well as chondrogenesis, skeletogenesis, angiogenesis and wound healing. The capacity of CTGF to interact with different growth factors lends an important role during early and late development, especially in the anterior region of the embryo...
July 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28887816/the-little-things-that-run-a-general-scaling-of-invertebrate-exploratory-speed-with-body-mass
#18
Myriam R Hirt, Tobias Lauermann, Ulrich Brose, Lucas P J J Noldus, Anthony I Dell
Speed is a key trait of animal movement, and while much is already known about vertebrate speed and how it scales with body mass, studies on invertebrates are sparse, especially across diverse taxonomic groups. Here, we used automated image-based tracking to characterize the exploratory (voluntary) speed of 173 invertebrates comprising 57 species across 6 taxonomic groups (Arachnida, Chilopoda, Diplopoda, Entognatha, Insecta, Malacostraca) and 4 feeding types (carnivore, detritivore, herbivore, omnivore). Across all individuals, exploratory speed scaled with body mass following a power-law relationship with a scaling exponent of 0...
September 8, 2017: Ecology
https://www.readbyqxmd.com/read/28885119/volume-of-distribution-and-clearance-of-peptide-based-nanofiber-after-convection-enhanced-delivery
#19
Ranjodh Singh, Vanessa Bellat, Melinda Wang, Melanie E Schweitzer, Y Linda Wu, Ching-Hsuan Tung, Mark M Souweidane, Benedict Law
OBJECTIVE Drug clearance may be a limiting factor in the clinical application of convection-enhanced delivery (CED). Peptide-based nanofibers (NFPs) have a high aspect ratio, and NFPs loaded with drugs could potentially maintain effective drug concentrations for an extended period sufficient for cancer therapy. The objective of this study was to assess the volume of distribution (Vd) and clearance of variable lengths of NFPs when administered using CED. METHODS NFPs composed of multiple methoxypolyethylene glycol (mPEG)-conjugated constructs (mPEG2000-KLDLKLDLKLDL-K( FITC)-CONH2, for which FITC is fluorescein isothiocyanate) were assembled in an aqueous buffer...
September 8, 2017: Journal of Neurosurgery
https://www.readbyqxmd.com/read/28884376/environmental-risk-assessment-of-lead-zinc-mining-a-case-study-of-adudu-metallogenic-province-middle-benue-trough-nigeria
#20
Ogbonnaya Igwe, Chuku Okoro Una, Ezekiel Abu, Ekundayo Joseph Adepehin
Assessment of the impacts of lead-zinc mining in Adudu-Imon metallogenic province was carried out. Reconnaissance and detailed field studies were done. Lithologies, stream sediments, farmland soils, mine tailings, artificial pond water, stream water, well water, and borehole water were collected and subjected to atomic absorption spectrometry (AAS) and X-ray fluorescence (XRF) analyses. Geochemical maps were generated using ArcGIS 10.1. Significant contamination with cadmium (Cd), iron (Fe), and lead (Pb) was recorded in the collected water samples...
September 7, 2017: Environmental Monitoring and Assessment
keyword
keyword
5032
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"