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https://www.readbyqxmd.com/read/28935164/elevated-expression-of-neuropeptide-signaling-genes-in-the-eyestalk-ganglia-and-y-organ-of-gecarcinus-lateralis-individuals-that-are-refractory-to-molt-induction
#1
Natalie L Pitts, Hanna M Schulz, Stephanie R Oatman, Donald L Mykles
Molting is induced in decapod crustaceans via multiple leg autotomy (MLA) or eyestalk ablation (ESA). MLA removes five or more walking legs, which are regenerated and become functional appendages at ecdysis. ESA eliminates the primary source of molt-inhibiting hormone (MIH) and crustacean hyperglycemic hormone (CHH), which suppress the production of molting hormones (ecdysteroids) from the molting gland or Y-organ (YO). Both MLA and ESA are effective methods for molt induction in Gecarcinus lateralis. However, some G...
September 18, 2017: Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology
https://www.readbyqxmd.com/read/28933541/correction-to-segregated-donor-acceptor-columns-in-liquid-crystals-that-exhibit-highly-efficient-ambipolar-charge-transport
#2
Hironobu Hayashi, Wataru Nihashi, Tomokazu Umeyama, Yoshihiro Matano, Shu Seki, Yo Shimizu, Hiroshi Imahori
No abstract text is available yet for this article.
September 21, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28930480/health-facility-staff-training-for-improving-breastfeeding-outcome-a-systematic-review-for-step-2-of-the-baby-friendly-hospital-initiative
#3
Olukunmi O Balogun, Amarjargal Dagvadorj, Jennifer Yourkavitch, Katharina da Silva Lopes, Maiko Suto, Yo Takemoto, Rintaro Mori, Pura Rayco-Solon, Erika Ota
The Baby-Friendly Hospital Initiative (BFHI) implemented through the "Ten Steps to Successful Breastfeeding" has been widely promoted as an intervention that improves breastfeeding rates. Step 2 requires the training of all healthcare staff in skills that are necessary to implement the policy. This systematic review provides evidence about the effect of training healthcare staff in hospitals and birth centers on breastfeeding outcomes. Randomized controlled trials (RCT), quasi-RCT, and controlled before and after (CBA) studies comparing training of healthcare staff on breastfeeding and supportive feeding practices with no training were included in this review...
September 20, 2017: Breastfeeding Medicine: the Official Journal of the Academy of Breastfeeding Medicine
https://www.readbyqxmd.com/read/28929183/altered-neurofilament-protein-expression-in-the-lateral-vestibular-nucleus-in-parkinson-s-disease
#4
Thomas P Wellings, Alan M Brichta, Rebecca Lim
A major cause of morbidity in Parkinson's disease (PD) is postural instability. The neuropathology underlying postural instability is unknown. Postural control is mediated by Deiters' neurons of the lateral vestibular nucleus (LVN), which are the brainstem origin of descending vestibulospinal reflexes. Deiters' neurons express the cytostructural protein, non-phosphorylated neurofilament protein (NPNFP). In PD, reduced expression of NPNFP in substantia nigra (SN) neurons is believed to contribute to dysfunction...
September 19, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28925290/differences-in-the-clinical-course-of-516-japanese-patients-with-upper-gastrointestinal-bleeding-between-weekday-and-weekend-admissions
#5
Minoru Fujita, Noriaki Manabe, Takahisa Murao, Motoyasu Osawa, Shinsuke Hirai, Shinya Fukushima, Yo Shogen, Rui Nakato, Manabu Ishii, Hiroshi Matsumoto, Jiro Hata, Akiko Shiotani
BACKGROUND AND AIMS: Patients suspected of having upper gastrointestinal bleeding (UGIB) admitted during the weekend tend to have a poor outcome in western countries. However, no Japanese studies have been reported on this matter. We aimed to evaluate differences in the clinical course of patients with UGIB between weekday and weekend admissions in Japan. METHODS: Medical records of patients who had undergone emergency endoscopy for UGIB were retrospectively reviewed...
September 19, 2017: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/28915556/critical-roles-of-smyd2-mediated-%C3%AE-catenin-methylation-for-nuclear-translocation-and-activation-of-wnt-signaling
#6
Xiaolan Deng, Ryuji Hamamoto, Theodore Vougiouklakis, Rui Wang, Yuichiro Yoshioka, Takehiro Suzuki, Naoshi Dohmae, Yo Matsuo, Jae-Hyun Park, Yusuke Nakamura
Accumulation of β-catenin in the nucleus is a hallmark of activation of the Wnt/β-catenin signaling pathway, which drives development of a large proportion of human cancers. However, the mechanism of β-catenin nuclear translocation has not been well investigated. Here we report biological significance of SMYD2-mediated lysine 133 (K133) methylation of β-catenin on its nuclear translocation. Knockdown of SMYD2 attenuates the nuclear localization of β-catenin protein in human cancer cells. Consequently, transcriptional levels of well-known Wnt-signaling molecules, cMYC and CCND1, are significantly reduced...
August 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28910381/genetic-characterization-of-blandm-harboring-plasmids-in-carbapenem-resistant-escherichia-coli-from-myanmar
#7
Yo Sugawara, Yukihiro Akeda, Noriko Sakamoto, Dan Takeuchi, Daisuke Motooka, Shota Nakamura, Hideharu Hagiya, Norihisa Yamamoto, Isao Nishi, Hisao Yoshida, Kazuhisa Okada, Khwar Nyo Zin, Mya Mya Aye, Kazunori Tonomo, Shigeyuki Hamada
The bacterial enzyme New Delhi metallo-β-lactamase hydrolyzes almost all β-lactam antibiotics, including carbapenems, which are drugs of last resort for severe bacterial infections. The spread of carbapenem-resistant Enterobacteriaceae that carry the New Delhi metallo-β-lactamase gene, blaNDM, poses a serious threat to public health. In this study, we genetically characterized eight carbapenem-resistant Escherichia coli isolates from a tertiary care hospital in Yangon, Myanmar. The eight isolates belonged to five multilocus-sequence types and harbored multiple antimicrobial-resistance genes, resulting in resistance against nearly all of the antimicrobial agents tested, except colistin and fosfomycin...
2017: PloS One
https://www.readbyqxmd.com/read/28904877/long-term-repeated-rituximab-treatment-for-childhood-steroid-dependent-nephrotic-syndrome
#8
Ji Hyun Kim, Eujin Park, Hye Sun Hyun, Myung Hyun Cho, Yo Han Ahn, Hyun Jin Choi, Hee Gyung Kang, Il-Soo Ha, Hae Il Cheong
BACKGROUND: Rituximab (RTX) can be used as a rescue therapy for steroid-dependent nephrotic syndrome (SDNS). However, the efficacy and safety of long-term, repeated use of RTX are not established. This study was conducted to assess the efficacy and safety of long-term, repeated RTX treatment in children. METHODS: Eighteen consecutive child patients with SDNS who were treated with three or more cycles of RTX for one year or longer were recruited, and their medical records were retrospectively reviewed...
September 2017: Kidney Research and Clinical Practice
https://www.readbyqxmd.com/read/28903460/correction-increased-expression-of-skp2-is-an-independent-predictor-of-locoregional-recurrence-in-cervical-cancer-via-promoting-dna-damage-response-after-irradiation
#9
Hung-Chun Fu, Yi-Chien Yang, Yun-Ju Chen, Hao Lin, Yu-Che Ou, Chan-Chao Chang Chien, Eng-Yen Huang, Hsuan-Ying Huang, Jui Lan, Hsi-Ping Chi, Ko-En Huang, Hong-Yo Kang
[This corrects the article DOI: 10.18632/oncotarget.10057.].
August 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28902776/pancreatic-cancer-arising-from-the-remnant-pancreas-is-it-a-local-recurrence-or-new-primary-lesion
#10
Daisuke Hashimoto, Akira Chikamoto, Toshiro Masuda, Shigeki Nakagawa, Katsunori Imai, Yo-Ichi Yamashita, Howard A Reber, Hideo Baba
Local recurrence of pancreatic cancer (PC) can occur in the pancreatic remnant. In addition, new primary PC can develop in the remnant. There are limited data available regarding this so-called remnant PC. The aim of this review was to describe the characteristics and therapeutic strategy regarding remnant PC. A literature search was performed using Medline published in English according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. The incidence of remnant PC has been reported to be 3% to 5%...
October 2017: Pancreas
https://www.readbyqxmd.com/read/28901495/biochanin-a-induces-apoptosis-and-suppresses-migration-in-fadu-human-pharynx-squamous-carcinoma-cells
#11
In-A Cho, Sang-Joun You, Kyeong-Rok Kang, Su-Gwan Kim, Ji-Su Oh, Jae-Seek You, Gyeong-Je Lee, Yo-Seob Seo, Do Kyung Kim, Chun Sung Kim, Sook-Young Lee, Jae-Sung Kim
The aim of the present study was to investigate biochanin-A-induced anticancer effects and their cellular signaling pathway in FaDu pharyngeal squamous carcinoma cells. Biochanin-A induced cell death through increased cytotoxicity of FaDu cells in a dose- and time-dependent manner. The number of cells with nucleus condensation and the apoptotic population were increased in the FaDu cells stimulated with biochanin-A for 24 h. Furthermore, extrinsic apoptotic factors such as FasL and their downstream target caspase-8 were increased and activated in the FaDu cells treated with biochanin-A in a dose-dependent manner...
September 13, 2017: Oncology Reports
https://www.readbyqxmd.com/read/28899642/evaluation-of-myocardial-function-according-to-early-diastolic-intraventricular-pressure-difference-in-fetuses
#12
Yuka Yamamoto, Ken Takahashi, Yo Takemoto, Maki Kobayashi, Keiichi Itatani, Toshiaki Shimizu, Atsuo Itakura, Satoru Takeda
BACKGROUND: Intraventricular pressure difference (IVPD), the diastolic suction during early diastole, is known as a useful marker of myocardial diastolic function in adults with different heart diseases, but there are no studies of fetal IVPD. The aim of this study was to determine whether IVPD exists and changes prenatally and whether IVPD correlates with preexisting parameters to evaluate fetal cardiac diastolic function and ventricular dominance. METHODS: Cross-sectional study data (stroke volume, fetal cardiac output, E/A ratio, and myocardial performance index) from 117 healthy fetuses at 17 to 36 weeks of gestation were retrospectively evaluated...
September 9, 2017: Journal of the American Society of Echocardiography
https://www.readbyqxmd.com/read/28899108/book-review-t%C3%A3-cnica-psicoanal%C3%A3-tica-aportaciones-de-la-psicolog%C3%A3-a-del-yo-psychoanalytic-technique-contributions-of-ego-psychology-t%C3%A3-cnica-psicoanal%C3%A3-tica-aportaciones-de-la-psicolog%C3%A3-a-del-yo-psychoanalytic-technique-contributions-of-ego-psychology-by-paniagua
#13
https://www.readbyqxmd.com/read/28899088/identification-of-siglec-ligands-using-a-proximity-labeling-method
#14
Lanyi Chang, Yi-Ju Chen, Chan-Yo Fan, Chin-Ju Tang, Yi-Hsiu Chen, Penk-Yeir Low, Albert Ventura, Chun-Cheng Lin, Yu-Ju Chen, Takashi Angata
Siglecs are a family of receptor-type glycan recognition proteins (lectins) involved in self-nonself discrimination by the immune system. Identification of Siglec ligands is necessary to understand how Siglec-ligand interaction translates into biological outcomes. However, this is challenging because the interaction is weak. To facilitate identification of Siglec ligands, we adopted a proximity labeling method based on the tyramide radicalization principle. Cells that express Siglec ligands were labeled with Siglec-peroxidase complexes and incubated with biotin tyramide and hydrogen peroxide, to generate short-lived tyramide radicals that covalently label the proteins near the Siglec-peroxidase complex...
September 13, 2017: Journal of Proteome Research
https://www.readbyqxmd.com/read/28899014/slow-wave-sleep-disruption-increases-cerebrospinal-fluid-amyloid-%C3%AE-levels
#15
Yo-El S Ju, Sharon J Ooms, Courtney Sutphen, Shannon L Macauley, Margaret A Zangrilli, Gina Jerome, Anne M Fagan, Emmanuel Mignot, John M Zempel, Jurgen A H R Claassen, David M Holtzman
See Mander et al. (doi:10.1093/awx174) for a scientific commentary on this article.Sleep deprivation increases amyloid-β, suggesting that chronically disrupted sleep may promote amyloid plaques and other downstream Alzheimer's disease pathologies including tauopathy or inflammation. To date, studies have not examined which aspect of sleep modulates amyloid-β or other Alzheimer's disease biomarkers. Seventeen healthy adults (age 35-65 years) without sleep disorders underwent 5-14 days of actigraphy, followed by slow wave activity disruption during polysomnogram, and cerebrospinal fluid collection the following morning for measurement of amyloid-β, tau, total protein, YKL-40, and hypocretin...
August 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28891102/co-oxidation-by-group-3-metal-monoxide-cations-supported-on-fe-co-4-2
#16
Mingfei Zhou, Chaoxian Chi, Hui Qu, Luyan Meng, Fanchen Kong, Mingbiao Luo
Infrared photodissociation spectroscopy of anions in the form of OMFe(CO)5- (M=Sc, Y, La) indicates that all these anions involve an 18-electron [Fe(CO)4]2- building block that is bonded with the M center through two bridged carbonyl ligands. The OLaFe(CO)5- anion is determined to be a CO-tagged complex involving a [Fe(CO)4]2-[LaO]+ anion core. In contrast, the OYFe(CO)5- anion is characterized to have a [Fe(CO)4]2-[Y(η2-CO2)]+ structure involving a side-on bonded CO2 ligand. The CO-tagged complex and the [Fe(CO)4]2-[Sc(η2-CO2)]+ isomer co-exist for the OScFe(CO)5- anion...
September 10, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/28888470/functional-and-biochemical-adaptations-of-elite-level-futsal-players-from-brazil-along-a-training-season
#17
Rômulo Pillon Barcelos, Guilherme Lopes Tocchetto, Frederico Diniz Lima, Sílvio Terra Stefanello, Harrison Fabricio Muzzy Rodrigues, Manuela Borges Sangoi, Rafael Noal Moresco, Luiz Fernando Freire Royes, Félix Alexandre Antunes Soares, Guilherme Bresciani
BACKGROUND AND OBJECTIVE: Although hard training is mandatory in elite level futsal training, few studies have proposed a biochemical follow up in futsal players during a whole season. Therefore, the aim of this study was to compare functional and biochemical markers in Brazilian elite level futsal players throughout a competition season. MATERIALS AND METHODS: Eight players aged 25.5±5.4 years were evaluated at three time points: preseason (T1), immediately before the FIFA(®)-Intercontinental-Futsal-Cup (T2), and at the end of the season (T3), with a tapering period of 1 week before T2...
August 26, 2017: Medicina
https://www.readbyqxmd.com/read/28887635/the-prognostic-impact-of-controlling-nutritional-status-conut-in-intrahepatic-cholangiocarcinoma-following-curative-hepatectomy-a-retrospective-single-institution-study
#18
Tatsunori Miyata, Yo-Ichi Yamashita, Takaaki Higashi, Katsunobu Taki, Daisuke Izumi, Keisuke Kosumi, Ryuma Tokunaga, Shigeki Nakagawa, Hirohisa Okabe, Katsunori Imai, Daisuke Hashimoto, Akira Chikamoto, Hideo Baba
BACKGROUND: Several studies have examined controlling nutritional status (CONUT), which is one of the useful biomarkers for predicting patients' prognosis following cancer treatment. The aim of this study was to evaluate the value of CONUT as a postoperative prognostic marker in patients with intrahepatic cholangiocarcinoma (ICC) following curative hepatectomy. METHODS: We retrospectively analyzed 71 patients who underwent curative hepatectomy for ICC between May 2002 and November 2016...
September 8, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/28885388/differences-in-physical-capacity-between-junior-and-senior-australian-footballers
#19
Stephen J Kelly, Mark L Watsford, Damien Austin, Rob W Spurrs, Matthew J Pine, Michael J Rennie
The purpose of this study was to profile and compare anthropometric and physical capacities within elite junior and senior Australian football (AF) players of various chronological ages and stages of athletic development. Seventy-nine players, including junior and senior AF players from one professional club were profiled using eleven assessments. Junior players were divided into two groups based on chronological age (under 16 and 18 years) and senior players according to years since drafted to a professional AF team (1-2 years, 3-7 years and 8+ years)...
September 5, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28878462/effect-of-task-oriented-activities-on-hand-functions-cognitive-functions-and-self-expression-of-elderly-patients-with-dementia
#20
Bo-Young Son, Yo-Soon Bang, Min-Ji Hwang, Eun-Ju Oh
[Purpose] This study investigates the effects of task-oriented activities on hand function, cognitive function, and self-expression of the elderly with dementia, and then identify the influencing factors on self-expression in sub-factors of dependent variables. [Subjects and Methods] Forty elderly persons were divided into two groups: intervention group (n=20) and control group (n=20). The interventions were applied to the subjects 3 times a week, 50 minutes per each time, for a total of five weeks. We measured the jamar hand dynamometer test for grip strength, the jamar hydraulic pinch gauge test for prehension test, nine-hole pegboard test for coordination test, and Loewenstein Occupational Therapy Cognitive Assessment-Geriatric Population for cognitive function, and self-expression rating scale for self-expression test...
August 2017: Journal of Physical Therapy Science
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