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Hardaway Chun-Kwan Chan, Weeraya Ka-Yan Ho, Patrick Shu-Hang Yung
Background/Objective: The aim of this study was to examine the effect of sprint cycling training on the intermittent run performance, sprinting speed, and change of direction (COD) ability of recreational intermittent sports athletes. Methods: Sixteen participants participated in the study. The experimental group (EG, n = 8) received a total of 12 sessions of sprint cycling training in a 4-week period and the control group (CG, n = 8) received no training. Both EG and CG were instructed to maintain their daily activity during the 4-week period...
January 2018: Asia-Pacific Journal of Sports Medicine, Arthroscopy, Rehabilitation and Technology
Yo-Han Uhm, Dae-Jung Yang
[Purpose] The purpose of this study was to examine the effect of computerized postural control training using whole body vibration on lower limb muscle activity and cerebral cortical activation in acute stroke patients. [Subjects and Methods] Thirty stroke patients participated and were divided into groups of 10, a group of the computerized postural control training using whole body vibration (Group I), the computerized postural control training combined with aero step (Group II) and computerized postural control training (Group III)...
February 2018: Journal of Physical Therapy Science
Haruki Katsumata, Izumi Yamamoto, Yo Komatsuzaki, Mayuko Kawabe, Yusuke Okabayashi, Takafumi Yamakawa, Ai Katsuma, Yasuyuki Nakada, Akimitsu Kobayashi, Yudo Tanno, Jun Miki, Hiroki Yamada, Ichiro Ohkido, Nobuo Tsuboi, Hiroyasu Yamamoto, Takashi Yokoo
BACKGROUND: Both prevention and treatment of recurrent immunoglobulin A nephropathy (IgAN) in kidney transplant recipients are important since recurrent IgAN seems to affect long-term graft survival. We present here a case of recurrent IgAN that was successfully treated using steroid pulse therapy plus tonsillectomy 10 years after kidney transplantation. CASE PRESENTATION: A 46-year-old male was admitted for an episode biopsy with a serum creatinine level of 1...
March 14, 2018: BMC Nephrology
Sarah K Mesrobian, Alessandro E P Villa, Michel Bader, Lorenz Götte, Alessandra Lintas
Attention-deficit hyperactivity disorder (ADHD) is characterized by deficits in executive functions and decision making during childhood and adolescence. Contradictory results exist whether altered event-related potentials (ERPs) in adults are associated with the tendency of ADHD patients toward risky behavior. Clinically diagnosed ADHD patients ( n = 18) and healthy controls ( n = 18), aged between 18 and 29 (median 22 Yo), were screened with the Conners' Adult ADHD Rating Scales and assessed by the Mini-International Neuropsychiatric Interview, adult ADHD Self-Report Scale, and by the 60-item HEXACO Personality Inventory...
2018: Frontiers in Human Neuroscience
Ricardo Dos Reis, Carlos E M C Andrade, Michael Frumovitz, Mark Munsell, Pedro T Ramirez
STUDY OBJECTIVE: The goal of our study is to compare outcomes of radical hysterectomy (RH) across age groups based on surgical approach. DESIGN: Cross-sectional study. CANADIAN TASK FORCE CLASSIFICATION: II-2 SETTING: Department of Gynecologic Oncology and Reproductive Medicine, The University of Texas MD Anderson Cancer Center. PATIENTS: We retrospectively reviewed patients with early-stage cervical cancer who underwent RH at a tertiary cancer center from 1990 to 2013...
March 9, 2018: Journal of Minimally Invasive Gynecology
Abdullah Shariff, Ruby Skinner, Andrea Pakula
INTRODUCTION: Visceral artery aneurysms are an uncommon clinical problem with aneurysms of the celiac artery only making up a small percentage of all visceral artery aneurysms. The more common splenic and hepatic aneurysms are often symptomatic with pain or rupture and associated hemorrhage. PRESENTATION OF CASE: We present a case of an otherwise healthy 30 yo male with an asymptomatic, posttraumatic arterial aneurysm of the celiac artery. He initially presented to our trauma center after sustaining multiple gunshot wounds which required multiple abdominal surgeries...
February 21, 2018: International Journal of Surgery Case Reports
Yo Seino, Takashi Hasegawa, Toshiyuki Koya, Takuro Sakagami, Ichiro Mashima, Natsue Shimizu, Yoshiyuki Muramatsu, Kumiko Muramatsu, Eiichi Suzuki, Toshiaki Kikuchi
Objective Whether or not depression affects the control or severity of asthma is unclear. We performed a cluster analysis of asthma patients with depressive symptoms to clarify their characteristics. Methods and subjects Multiple medical institutions in Niigata Prefecture, Japan, were surveyed in 2014. We recorded the age, disease duration, body mass index (BMI), medications, and surveyed asthma control status and severity, as well as depressive symptoms and adherence to treatment using questionnaires. A hierarchical cluster analysis was performed on the group of patients assessed as having depression...
March 9, 2018: Internal Medicine
Hiroyuki Komatsu, Junya Yamamoto, Hiromichi Suzuki, Nobuyoshi Nagao, Yuu Hirose, Takashi Ohyama, So Umekage, Yo Kikuchi
The marine bacterium Rhodovulum sulfidophilum is a nonsulfur phototrophic bacterium, which is known to produce extracellular nucleic acids in soluble form in culture medium. In the present paper, constructing the response regulator ctrA-deficient mutant of R. sulfidophilum, we found that this mutation causes a significant decrease in the extracellular DNA production. However, by the introduction of a plasmid containing the wild type ctrA gene into the mutant, the amount of extracellular DNA produced was recovered...
March 12, 2018: Journal of General and Applied Microbiology
Danny Eizicovits, Yael Edan, Iris Tabak, Shelly Levy-Tzedek
BACKGROUND: Effective human-robot interactions in rehabilitation necessitates an understanding of how these should be tailored to the needs of the human. We report on a robotic system developed as a partner on a 3-D everyday task, using a gamified approach. OBJECTIVES: To: (1) design and test a prototype system, to be ultimately used for upper-limb rehabilitation; (2) evaluate how age affects the response to such a robotic system; and (3) identify whether the robot's physical embodiment is an important aspect in motivating users to complete a set of repetitive tasks...
2018: Restorative Neurology and Neuroscience
Yo Han Kwon, Krysten Minnici, Jung Jin Park, Sujin R Lee, Guoyan Zhang, Esther S Takeuchi, Kenneth J Takeuchi, Amy C Marschilok, Elsa Reichmanis
Conjugated polymers possessing polar functionalities were shown to effectively anchor single-walled carbon nanotubes (SWNTs) to the surface of high-capacity anode materials, and enable the formation of electrical networks. Specifically, poly[3-(potassium-4-butanoate) thiophene] (PPBT) served as a bridge between SWNT networks and various anode materials, including monodispersed Fe3O4 spheres (sFe3O4), and silicon nanoparticles (Si NPs). The PPBT π‒conjugated backbone and carboxylate (COO‒) substituted alkyl side chains, respectively, attracted the SWNT π‒electron surface and chemically interacted with active material surface hydroxyl (‒OH) species to form a carboxylate bond...
March 10, 2018: Journal of the American Chemical Society
Mehmet Tecellioglu, Ozden Kamisli, Suat Kamisli, Fatma Ebru Yucel, Cemal Ozcan
BACKGROUND: Autoimmune epilepsy is a rarely diagnosed condition. Recognition of the underlying autoimmune condition is important, as these patients can be resistant to antiepileptic drugs. AIMS: To determine the autoimmune and oncological antibodies in adult drug-resistant epilepsy of unknown cause and identify the clinical, radiological, and EEG findings associated with these antibodies according to data in the literature. METHODS: Eighty-two patients with drug-resistant epilepsy of unknown cause were prospectively identified...
March 9, 2018: Irish Journal of Medical Science
Alexander P Christensen, Yoed N Kenett, Tomaso Aste, Paul J Silvia, Thomas R Kwapil
Schizotypy is a multidimensional construct that provides a useful framework for understanding the etiology, development, and risk for schizophrenia-spectrum disorders. Past research has applied traditional methods, such as factor analysis, to uncovering common dimensions of schizotypy. In the present study, we aimed to advance the construct of schizotypy, measured by the Wisconsin Schizotypy Scales-Short Forms (WSS-SF), beyond this general scope by applying two different psychometric network filtering approaches-the state-of-the-art approach (lasso), which has been employed in previous studies, and an alternative approach (information-filtering networks; IFNs)...
March 8, 2018: Behavior Research Methods
Won Hye Ka, Seok Keun Cho, Byung Nyun Chun, Sang Yo Byun, Jong Cheol Ahn
BACKGROUND: The E3 ubiquitin ligase constitutive photomorphogenic 1 (COP1) mediates cell survival, growth, and development, and interacts with the tumor suppressor protein p53 to induce its ubiquitination and degradation. Recent studies reported that COP1 overexpression is associated with increased cell proliferation, transformation, and disease progression in a variety of cancer types. In this study, we investigated whether COP1 regulates p53-mediated cell cycle arrest and apoptosis in human breast cancer cell lines...
March 7, 2018: Breast Cancer: the Journal of the Japanese Breast Cancer Society
Jennifer M Reinhart, Warren Rose, Daniel J Panyard, Michael A Newton, Tyler K Liebenstein, Jeremiah Yee, Lauren A Trepanier
The lymphocyte toxicity assay (LTA) is a proposed surrogate marker of sulfonamide antibiotic hypersensitivity. In the LTA, peripheral blood mononuclear cells (PBMCs) undergo apoptosis more readily in hypersensitive versus tolerant patients when exposed to drug-hydroxylamine metabolites in vitro. The purpose of this study was to identify key gene transcripts associated with increased cytotoxicity from sulfamethoxazole-hydroxylamine in human PBMCs in the LTA. The LTA was performed on PBMCs of 10 patients hypersensitive to trimethoprim-sulfamethoxazole (HS) and 10 drug-tolerant controls (TOL), using two cytotoxicity assays: YO-PRO (n = 20) and MTT (n = 12)...
April 2018: Pharmacology Research & Perspectives
Sayaka Aikawa, Hiroyuki Kobayashi, Takahiro Nemoto, Satoshi Matsuo, Yo Wada, Noriyuki Mamiya, Taiju Yamaguchi, Naoyuki Katagiri, Naohisa Tsujino, Masafumi Mizuno
Social anxiety is commonly reported as a comorbid condition among people with schizophrenia. The aims of this study were to elucidate the associations between demographic/clinical features and social anxiety. A total of 207 outpatients with schizophrenia underwent assessments for social anxiety, psychiatric symptoms, social cognition, cognitive function, social functioning, and quality of life (QOL). To confirm the prediction model for social anxiety, we conducted multiple linear regressions using the Liebowitz Social Anxiety Scale (LSAS) score as an outcome variable and demographic/clinical variables as predictors...
February 20, 2018: Psychiatry Research
Yo-Han Kim, Hanju Yoo, A-Reum Hong, Minseo Kwon, Sang-Wook Kang, Kyunggon Kim, Youngsup Song
The transcription factor cAMP-responsive element-binding protein (CREB) is involved in a variety of physiologic processes. Although its activity appears to be largely correlated with its phosphorylation status, cAMP-mediated dephosphorylation and the subsequent nuclear migration of the CREB-regulated transcription factors (CRTCs) are required to stimulate CREB transcriptional activity. Among the 3 identified mammalian homologs of CRTCs, CRTC3 has been shown to be expressed predominantly in adipose tissues in response to catecholamine signals that regulate lipid metabolism...
March 5, 2018: FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology
Motoo Nomura, Atsushi Otsuka, Michio Yoshimura, Yumi Nonomura, Yo Kaku, Shigemi Matsumoto, Manabu Muto
BACKGROUND: The objective of this study was to evaluate the efficacy and safety of concurrent immune checkpoint inhibitor therapy and radiotherapy (immunoradiotherapy) in patients with metastatic melanoma after progression on nivolumab. PATIENTS AND METHODS: A retrospective review was performed on 16 consecutive patients with metastatic melanoma treated with concurrent immunoradiotherapy after progression on nivolumab. Best responses to immunoradiotherapy were assessed either inside or outside of the radiation fields...
March 3, 2018: Cancer Chemotherapy and Pharmacology
Koichi Kinoshita, Toru Beppu, Tatsunori Miyata, Kunitaka Kuramoto, Yasushi Yoshida, Naoki Umesaki, Yuki Kitano, Shigeki Nakagawa, Hirohisa Okabe, Hidetoshi Nitta, Katsunori Imai, Hiromitsu Hayashi, Yo-Ichi Yamashita, Hiroyuki Komori, Kei Horino, Atsunobu Misumi, Hideo Baba
A 70-year-old man with a growing liver tumor had undergone subtotal gastrectomy with pancreaticoduodenectomy for gastric cancer (T4b P0 H0 N1, Stage IIIB) 30 months before admission to our hospital. Enhanced computed tomography revealed two hypervascular nodules in segments 4 and 8. After histological diagnosis of small liver metastases from gastric cancer in segment 8, the patient underwent open microwave coagulation therapy (MCT) for the tumor (diameter: 30 mm) in segment 4. MCT was performed by using 1.5-cm and 3-cm monopolar needle electrodes with 22 times of puncture under the condition of 100 W × 60 sec...
March 2018: Anticancer Research
Estibaliz Romaratezabala, Fabio Nakamura, Rodrigo Ramirez-Campillo, Daniel Castillo, Josune Rodríguez-Negro, Javier Yanci
The aim of this study was to compare physical performance in amateur handball players of two different competitive levels. Thirty-four senior handball players were divided into two groups according to their competitive level (regional category: REG or national category: NAC). Although no significant differences were found between groups in any of the horizontal (HJ) or vertical jump (VJ) variables (p>0.05), NAC players obtained a better performance in the repeated sprint ability (RSA) test (RSABest [the best attempt] and RSATT [the total time in the total of sprints] in 15 m and 30 m), in change of direction ability (CODA) and in the Yo-Yo Intermittent Recovery test Level 1 (YYIR1) test (p<0...
February 27, 2018: Journal of Strength and Conditioning Research
Kohei Inui, Yuki Nakagawa, Go Hasegawa, Yohei Ikeda, Yo Sato, Tsutomu Nishiyama, Yoshihiko Tomita
No abstract text is available yet for this article.
March 2018: Urology Case Reports
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