keyword
MENU ▼
Read by QxMD icon Read
search

Yo

keyword
https://www.readbyqxmd.com/read/29779490/a-back-to-back-tumor-composed-of-papillary-renal-cell-carcinoma-and-oncocytoma-treated-by-laparoscopic-partial-nephrectomy-a-case-report
#1
Su Hwan Kang, Won Tae Seo, Pil Moon Kang, Hyun Yul Rhew, Yo Han Jeon, Bong Kwon Cheon, Taek Sang Kim
BACKGROUND: Renal oncocytoma is the most common benign renal tumor, and papillary renal cell carcinoma is the second most common histologic subtype of renal cell carcinoma. Renal tumors containing different components such as papillary renal cell carcinoma and oncocytoma are extremely rare. CASE PRESENTATION: A renal mass was incidentally detected in a 52-year-old Korean woman, and a computed tomographic scan showed a 32-mm multicystic mass with some calcifications in the lower pole of the right kidney...
May 21, 2018: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29767743/premeal-low-fat-yogurt-consumption-reduces-postprandial-inflammation-and-markers-of-endotoxin-exposure-in-healthy-premenopausal-women-in-a-randomized-controlled-trial
#2
Ruisong Pei, Diana M DiMarco, Kelley K Putt, Derek A Martin, Chureeporn Chitchumroonchokchai, Richard S Bruno, Bradley W Bolling
Background: Metabolic endotoxemia is associated with obesity and contributes to postprandial inflammation. Objective: We aimed to determine if low-fat yogurt consumption prevents postprandial inflammation and dysmetabolism in healthy women by inhibiting biomarkers of metabolic endotoxemia. Methods: Premenopausal women defined as obese and nonobese [body mass index (BMI, in kg/m2) 30-40 and 18.5-27, respectively, n = 120] were randomly assigned to consume 339 g of low-fat yogurt (YN, yogurt nonobese; YO, yogurt obese) or 324 g of soy pudding (CN, control nonobese; CO, control obese) for 9 wk (n = 30/group)...
May 15, 2018: Journal of Nutrition
https://www.readbyqxmd.com/read/29767342/characterization-of-xanthine-dehydrogenase-and-aldehyde-oxidase-of-marsupenaeus-japonicus-and-their-response-to-microbial-pathogen
#3
Yo Okamura, Mari Inada, Gehad Elsaid Elshopakey, Toshiaki Itami
Reactive oxygen species (ROS) play key roles in many physiological processes. In particular, the sterilization mechanism of bacteria using ROS in macrophages is a very important function for biological defense. Xanthine dehydrogenase (XDH) and aldehyde oxidase (AOX), members of the molybdo-flavoenzyme subfamily, are known to generate ROS. Although these enzymes occur in many vertebrates, some insects, and plants, little research has been conducted on XDHs and AOXs in crustaceans. Here, we cloned the entire cDNA sequences of XDH (MjXDH: 4328 bp) and AOX (MjAOX: 4425 bp) from Marsupenaeus japonicus (kuruma shrimp) using reverse transcriptase-polymerase chain reaction (RT-PCR) and random amplification of cDNA ends (RACE)...
May 16, 2018: Molecular Biology Reports
https://www.readbyqxmd.com/read/29759640/enhancer-of-zeste-homolog-2-ezh2-regulates-tumor-angiogenesis-and-predicts-recurrence-and-prognosis-of-intrahepatic-cholangiocarcinoma
#4
Shigeki Nakagawa, Hirohisa Okabe, Mayuko Ouchi, Ryuma Tokunaga, Naoki Umezaki, Takaaki Higashi, Takatoshi Kaida, Kota Arima, Yuki Kitano, Hideyuki Kuroki, Kosuke Mima, Hidetoshi Nitta, Katsunori Imai, Daisuke Hashimoto, Yo-Ichi Yamashita, Akira Chikamoto, Hideo Baba
BACKGROUND: Enhancer of zeste homolog 2 (EZH2) is the catalytic subunit of the polycomb repressive complex 2 (PRC2) and regulates tumor malignancy by gene silencing via histone methylation. In this study we investigate the role of EZH2 in angiogenesis of intrahepatic cholangiocarcinoma (ICC). METHODS: The influence of EZH2 on tumor angiogenesis was examined by bioinformatics analysis of a public database. We also assessed the correlation between EZH2 and vasohibin 1 (VASH1) expression in 47 patients with ICC by immunohistochemical (IHC) staining and in vitro gene silencing assays...
May 11, 2018: HPB: the Official Journal of the International Hepato Pancreato Biliary Association
https://www.readbyqxmd.com/read/29755690/prognostic-value-of-line-1-methylation-level-in-321-patients-with-primary-liver-cancer-including-hepatocellular-carcinoma-and-intrahepatic-cholangiocarcinoma
#5
Tatsunori Miyata, Yo-Ichi Yamashita, Yoshifumi Baba, Kazuto Harada, Takanobu Yamao, Naoki Umezaki, Masayo Tsukamoto, Yuki Kitano, Kensuke Yamamura, Kota Arima, Shigeki Nakagawa, Hirohisa Okabe, Katsunori Imai, Daisuke Hashimoto, Akira Chikamoto, Mototsugu Shimokawa, Hideo Baba
Background: The methylation level of long interspersed nucleotide element-1 (LINE-1) is a good surrogate marker of the global DNA methylation level. The relationship between LINE-1 methylation level and prognosis in primary liver cancer (PLC) patients remains unclear. Results: LINE-1 methylation levels were significantly lower in HCC and cHCC-CC tissues, but not in ICC tissues, than those in noncancerous liver parenchyma (HCC: p < 0.0001; cHCC-CC: p < 0.001; and ICC: p = 0...
April 17, 2018: Oncotarget
https://www.readbyqxmd.com/read/29755584/development-and-validation-of-an-age-specific-lower-extremity-finite-element-model-for-simulating-pedestrian-accidents
#6
Jing Huang, Yongcheng Long, Yu Yan, Lin Hu
The objective of the present study is to develop an age-specific lower extremity finite element model for pedestrian accident simulation. Finite element (FE) models have been used as a versatile tool to simulate and understand the pedestrian injury mechanisms and assess injury risk during crashes. However, current computational models only represent certain ages in the population, the age spectrum of the pedestrian victims is very large, and the geometry of anatomical structures and material property of the lower extremities changes with age for adults, which could affect the injury tolerance, especially in at-risk populations such as the elderly...
2018: Applied Bionics and Biomechanics
https://www.readbyqxmd.com/read/29753689/molecular-characterization-and-gene-expression-analysis-of-hypoxia-inducible-factor-and-its-inhibitory-factors-in-kuruma-shrimp-marsupenaeus-japonicus
#7
Yo Okamura, Tohru Mekata, Gehad Elsaid Elshopakey, Toshiaki Itami
In shrimp aquaculture, overcrowded farming causes fluctuations in dissolved oxygen concentrations. Low-oxygen conditions (hypoxia) affect shrimp growth. Hypoxia-inducible factor (HIF) is a transcriptional factor in the basic helix-loop-helix/PAS family and is activated in response to hypoxic stress. However, little is known about HIF and other inhibitors of the HIF pathway in crustaceans. In this study, we cloned MjHIF-1α, an inhibitory factor, MjFIH-1 (factor inhibiting HIF-1α), and MjVHL (Von Hippel-Lindau tumor suppressor) from kuruma shrimp (Marsupenaeus japonicus)...
May 10, 2018: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/29747676/epithelioid-cell-histiocytoma-with-sqstm1-alk-fusion-a-case-report
#8
Ryuko Nakayama, Yuki Togashi, Satoko Baba, Yo Kaku, Yuki Teramoto, Takaki Sakurai, Hironori Haga, Kengo Takeuchi
BACKGROUND: Epithelioid cell histiocytoma (ECH), which is also known as epithelioid benign fibrous histiocytoma, has been classified as a rare variant of fibrous histiocytoma (FH). However, the recent detection of ALK protein expression and/or ALK gene rearrangement in ECH suggests that it might be biologically different from conventional FH. CASE PRESENTATION: A 27-year-old male presented with nodule on his left foot, which had been present for 5 years. A macroscopic examination revealed an exophytic, hyperkeratotic nodule on the dorsum of the left foot...
May 10, 2018: Diagnostic Pathology
https://www.readbyqxmd.com/read/29746505/the-effects-of-short-term-detraining-and-retraining-on-physical-fitness-in-elite-soccer-players
#9
Chang Hwa Joo
PURPOSE: The aim of this study was to examine the effects of aerobic high-intensity training with reduced volume and training cessation on body composition and physical fitness after the end of season and the time required to recapture physical fitness with intensified retraining following two weeks of detraining in elite soccer players. METHOD: Twenty male semi-professional soccer players participated in this study. The soccer players were assigned to either a group that completed high-intensity aerobic training (HAT, n = 10) or to a detraining and retraining group (DHAT, n = 10) for a 5-week period immediately after the end of the season...
2018: PloS One
https://www.readbyqxmd.com/read/29743490/transcriptomic-analysis-of-crustacean-molting-gland-y-organ-regulation-via-the-mtor-signaling-pathway
#10
S Shyamal, S Das, A Guruacharya, D L Mykles, D S Durica
The intermolt crustacean Y-organ (YO) maintains a basal state mediated by pulsatile release of molt inhibiting hormone (MIH), a neuropeptide produced in the eyestalk ganglia, inhibiting YO ecdysteroidogenesis. Reduction of MIH results in YO activation and the animal enters premolt. In the crab, Gecarcinus lateralis, molting was induced by eyestalk ablation (ESA). ESA animals were injected with either rapamycin, an mTOR inhibitor, or DMSO vehicle at Day 0. YOs were harvested at 1, 3, and 7 days post-ESA and processed for high throughput RNA sequencing...
May 9, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29743446/photodynamic-therapy-using-talaporfin-sodium-induces-heme-oxygenase-1-expression-in-rat-malignant-meningioma-kmy-j-cells
#11
Tsutomu Takahashi, Saki Suzuki, Suzuka Misawa, Jiro Akimoto, Yo Shinoda, Yasuyuki Fujiwara
Photodynamic therapy (PDT) using talaporfin sodium (TS) is tumor cell-selective less invasive therapy for the treatment of malignant glioma. We previously demonstrated that PDT using TS (TS-PDT) treatment exhibits anti-tumor activity against not only glioblastoma cells but also malignant meningioma cells. In general, various stress response proteins have been reported to affect the sensitivity determination for anticancer agents against tumor cells. However, the relationship between the therapeutic effect of TS-PDT and stress response systems in tumor cells is not adequately investigated...
2018: Journal of Toxicological Sciences
https://www.readbyqxmd.com/read/29736153/tabetri%C3%A2-tabebuia-avellanedae-ethanol-extract-ameliorates-atopic-dermatitis-symptoms-in-mice
#12
Jae Gwang Park, Young-Su Yi, Sang Yun Han, Yo Han Hong, Sulgi Yoo, Eunji Kim, Seong-Gu Jeong, Adithan Aravinthan, Kwang Soo Baik, Su Young Choi, Jung-Il Kim, Young-Jin Son, Jong-Hoon Kim, Jae Youl Cho
Tabebuia avellanedae has been traditionally used as an herbal remedy to alleviate various diseases. However, the plant's pharmacological activity in allergic and inflammatory diseases and its underlying mechanism are not fully understood. Therefore, we investigated the pharmacological activity of Tabetri ( T. avellanedae ethanol extract (Ta-EE)) in the pathogenesis of AD. Its underlying mechanism was explored using an AD mouse model and splenocytes isolated from this model. Ta-EE ameliorated the AD symptoms without any toxicity and protected the skin of 2,4-dinitrochlorobenzene- (DNCB-) induced AD mice from damage and epidermal thickness...
2018: Mediators of Inflammation
https://www.readbyqxmd.com/read/29725523/suppression-of-osteoclastogenesis-via-%C3%AE-2-adrenergic-receptors
#13
Kosuke Hamajima, Kazunori Hamamura, Andy Chen, Hiroki Yokota, Hironori Mori, Shoyoku Yo, Hisataka Kondo, Kenjiro Tanaka, Kyoko Ishizuka, Daisuke Kodama, Takao Hirai, Ken Miyazawa, Shigemi Goto, Akifumi Togari
The sympathetic nervous system is known to regulate osteoclast development. However, the involvement of α2-adrenergic receptors (α2-ARs) in osteoclastogenesis is not well understood. In the present study, their potential role in osteoclastogenesis was investigated. Guanabenz, clonidine and xylazine were used as agonists of α2-ARs, while yohimbine and idazoxan were employed as antagonists. Using RAW264.7 pre-osteoclast and primary bone marrow cells, the mRNA expression of the osteoclast-related genes nuclear factor of activated T-cells, cytoplasmic 1 (NFATc1), tartrate-resistant acid phosphatase (TRAP) and cathepsin K was evaluated following induction with receptor activator of nuclear factor κB ligand (RANKL)...
May 2018: Biomedical Reports
https://www.readbyqxmd.com/read/29725354/src-is-a-prime-target-inhibited-by-celtis-choseniana-methanol-extract-in-its-anti-inflammatory-action
#14
Han Gyung Kim, Subin Choi, Jongsung Lee, Yo Han Hong, Deok Jeong, Keejung Yoon, Deok Hyo Yoon, Gi-Ho Sung, Seungihm Lee, Suntaek Hong, Young-Su Yi, Jong-Hoon Kim, Jae Youl Cho
Celtis choseniana is the traditional plant used at Korea as a herbal medicine to ameliorate inflammatory responses. Although Celtis choseniana has been traditionally used as a herbal medicine at Korea, no systemic research has been conducted on its anti-inflammatory activity. Therefore, the present study explored an anti-inflammatory effect and its underlying molecular mechanism using Celtis choseniana methanol extract (Cc-ME) in macrophage-mediated inflammatory responses. In vitro anti-inflammatory activity of Cc-ME was evaluated using RAW264...
2018: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/29724814/ahnak-loss-in-mice-promotes-type-ii-pneumocyte-hyperplasia-and-lung-tumor-development
#15
Jun Won Park, Il-Yong Kim, Ji Won Choi, Hee Jung Lim, Jae Hoon Shin, Yo Na Kim, Seo Hyun Lee, Yeri Son, Mira Sohn, Jong Kyu Woo, Joseph H Jeong, Cheolju Lee, Yun Soo Bae, Je Kyung Seong
AHNAK is known to be a tumor suppressor in breast cancer due to its ability to activate the TGFbeta signaling pathway. However, the role of AHNAK in lung tumor development and progression remains unknown. Here, the Ahnak gene was disrupted to determine its effect on lung tumorigenesis and the mechanism by which it triggers lung tumor development was investigated. First, AHNAK protein expression was determined to be decreased in human lung adenocarcinomas compared with matched non-neoplastic lung tissues. Then, Ahnak-/- mice were used to investigate the role of AHNAK in pulmonary tumorigenesis...
May 3, 2018: Molecular Cancer Research: MCR
https://www.readbyqxmd.com/read/29720268/specific-markers-and-properties-of-synovial-mesenchymal-stem-cells-in-the-surface-stromal-and-perivascular-regions
#16
Mitsuru Mizuno, Hisako Katano, Yo Mabuchi, Yusuke Ogata, Shizuko Ichinose, Shizuka Fujii, Koji Otabe, Keiichiro Komori, Nobutake Ozeki, Hideyuki Koga, Kunikazu Tsuji, Chihiro Akazawa, Takeshi Muneta, Ichiro Sekiya
BACKGROUND: Synovial mesenchymal stem cells (MSCs) are an attractive cell source for cartilage and meniscus regeneration. Synovial tissue can be histologically classified into three regions; surface, stromal and perivascular region, but the localization of synovial MSCs has not been fully investigated. We identified markers specific for each region, and compared properties of MSCs derived from each region in the synovium. METHODS: The intensity of immunostaining with 19 antibodies was examined for surface, stromal, and perivascular regions of human synovium from six osteoarthritis patients...
May 2, 2018: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/29719469/the-skin-protective-effects-of-compound-k-a-metabolite-of-ginsenoside-rb1-from-panax-ginseng
#17
Eunji Kim, Donghyun Kim, Sulgi Yoo, Yo Han Hong, Sang Yun Han, Seonggu Jeong, Deok Jeong, Jong-Hoon Kim, Jae Youl Cho, Junseong Park
Background: Compound K (CK) is a ginsenoside, a metabolite of Panax ginseng . There is interest both in increasing skin health and antiaging using natural skin care products. In this study, we explored the possibility of using CK as a cosmetic ingredient. Methods: To assess the antiaging effect of CK, RT-PCR was performed, and expression levels of matrix metalloproteinase-1, cyclooxygenase-2, and type I collagen were measured under UVB irradiation conditions. The skin hydrating effect of CK was tested by RT-PCR, and its regulation was explored through immunoblotting...
April 2018: Journal of Ginseng Research
https://www.readbyqxmd.com/read/29719374/clinical-course-of-thyroid-function-and-thyroid-associated-ophthalmopathy-in-patients-with-euthyroid-graves-disease
#18
Nami Suzuki, Jaeduk Yoshimura Noh, Toshiaki Kameda, Ai Yoshihara, Hidemi Ohye, Miho Suzuki, Masako Matsumoto, Yo Kunii, Kenji Iwaku, Natsuko Watanabe, Koji Mukasa, Ai Kozaki, Toshu Inoue, Kiminori Sugino, Koichi Ito
Background: Euthyroid Graves' disease (EGD) is a rare condition defined as the presence of thyroid-associated ophthalmopathy (TAO) in patients with normal thyroid function. Due to the rarity of this disease, only a limited number of studies and case reports are available for further evaluation of the characteristics of the disease. The aim of this study was to examine the changes in the thyroid function, thyrotropin receptor antibodies (TRAb) and eye symptoms, and then determine whether TRAb is related to TAO in EGD patients...
2018: Clinical Ophthalmology
https://www.readbyqxmd.com/read/29706144/genotype-imputation-from-various-low-density-snp-panels-and-its-impact-on-accuracy-of-genomic-breeding-values-in-pigs
#19
D A Grossi, L F Brito, M Jafarikia, F S Schenkel, Z Feng
The uptake of genomic selection (GS) by the swine industry is still limited by the costs of genotyping. A feasible alternative to overcome this challenge is to genotype animals using an affordable low-density (LD) single nucleotide polymorphism (SNP) chip panel followed by accurate imputation to a high-density panel. Therefore, the main objective of this study was to screen incremental densities of LD panels in order to systematically identify one that balances the tradeoffs among imputation accuracy, prediction accuracy of genomic estimated breeding values (GEBVs), and genotype density (directly associated with genotyping costs)...
April 30, 2018: Animal: An International Journal of Animal Bioscience
https://www.readbyqxmd.com/read/29702517/assessing-repeated-sprint-ability-in-division-i-collegiate-women-soccer-players
#20
Robert G Lockie, Tricia M Liu, Alyssa A Stage, Adrina Lazar, Dominic V Giuliano, Jillian M Hurley, Ibett A Torne, Megan D Beiley, Samantha A Birmingham-Babauta, John J Stokes, Fabrice G Risso, DeShaun L Davis, Matthew R Moreno, Ashley J Orjalo
Lockie, RG, Liu, TM, Stage, AA, Lazar, A, Giuliano, DV, Hurley, JM, Torne, IA, Beiley, MD, Birmingham-Babauta, SA, Stokes, JJ, Risso, FG, Davis, DL, Moreno, MR, and Orjalo, AJ. Assessing repeated-sprint ability in Division I collegiate women soccer players. J Strength Cond Res XX(X): 000-000, 2018-Repeated-sprint ability (RSA) is a key component of soccer, and is the capacity to repeatedly produce near-maximal to maximal sprints with short recovery periods. Repeated-sprint ability has received little analysis in collegiate women soccer players...
April 26, 2018: Journal of Strength and Conditioning Research
keyword
keyword
50313
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"