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https://www.readbyqxmd.com/read/29329330/obesity-and-abnormal-glucose-tolerance-in-offspring-of-diabetic-mothers-a-systematic-review-and-meta-analysis
#1
Maki Kawasaki, Naoko Arata, Celine Miyazaki, Rintaro Mori, Toru Kikuchi, Yoshihiro Ogawa, Erika Ota
BACKGROUND: Rising prevalence of childhood obesity and type 2 diabetes mellitus (T2DM) is an emerging public health issue. OBJECTIVES: To investigate the association of maternal hyperglycemia exposure during pregnancy with obesity and abnormal glucose tolerance in offspring, and the age at occurrence. METHODS: We searched MEDLINE and EMBASE for observational studies on obesity and diabetes in offspring of diabetic mothers (gestational diabetes mellitus (GDM), type 1 diabetes mellitus (T1DM) and T2DM), and those on non-diabetic mothers...
2018: PloS One
https://www.readbyqxmd.com/read/29310344/polymyositis-with-elevated-serum-igg4-levels-and-abundant-igg4-plasma-cell-infiltration-a-case-report-and-literature-review
#2
Ryusuke Anan, Mitsuhiro Akiyama, Yuko Kaneko, Jun Kikuchi, Kazuko Suzuki, Shiro Matsubara, Tsutomu Takeuchi
INTRODUCTION: Polymyositis (PM) is a type of autoimmune, inflammatory myopathy. IgG4-related disease (IgG4-RD) is a recently recognized disease entity characterized by elevated serum IgG4 levels and IgG4 plasma-cell infiltration of various organs. However, several reports have described cases of other diseases that present with those features, suggesting the importance of careful differential diagnosis. Herein, we report the first case of PM with elevated serum IgG4 levels and IgG4 plasma cells in the muscles, mimicking IgG4-RD...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29228187/extracellular-nucleic-acids-of-the-marine-bacterium-rhodovulum-sulfidophilum-and-recombinant-rna-production-technology-using-bacteria
#3
Yo Kikuchi, So Umekage
Extracellular nucleic acids of high molecular weight are detected ubiquitously in seawater. Recent studies have indicated that these nucleic acids are, at least in part, derived from active production by some bacteria. The marine bacterium Rhodovulum sulfidophilum is one of those bacteria. Rdv. sulfidophilum is a non-sulfur phototrophic marine bacterium, which is known to form flocs, structured communities of cells, and to produce extracellular nucleic acids in culture media. Recently, it has been revealed that this bacterium produces gene transfer agent-like particles and that this particle production may be related to the extracellular nucleic acid production mechanism...
December 6, 2017: FEMS Microbiology Letters
https://www.readbyqxmd.com/read/29220607/case-of-cone-dystrophy-with-normal-fundus-appearance-associated-with-biallelic-poc1b-variants
#4
Azusa Kominami, Shinji Ueno, Taro Kominami, Ayami Nakanishi, Yasuki Ito, Kaoru Fujinami, Kazushige Tsunoda, Takaaki Hayashi, Sachiko Kikuchi, Shuhei Kameya, Takeshi Iwata, Hiroko Terasaki
BACKGROUND: Biallelic variants of POC1B were recently reported to cause autosomal recessive non-syndromic cone dystrophy. However, the number of studies supporting this is limited, and the clinical phenotypes of cone dystrophy have not been definitively determined. The purpose of this study was to report the phenotype of a case of POC1B-associated cone dystrophy. MATERIALS AND METHODS: The medical chart of one case diagnosed with cone dystrophy was reviewed. RESULTS: The patient was a 20-year-old Japanese man whose chief complaint was a progressive decrease in his central vision...
December 8, 2017: Ophthalmic Genetics
https://www.readbyqxmd.com/read/29220371/the-impact-of-different-anti-vascular-endothelial-growth-factor-treatment-regimens-on-reducing-burden-for-caregivers-and-patients-with-wet-age-related-macular-degeneration-in-a-single-center-real-world-japanese-setting
#5
Tsukasa Hanemoto, Yusuke Hikichi, Norimasa Kikuchi, Tadahiko Kozawa
OBJECTIVE: To describe the burden associated with different anti-vascular endothelial growth factor (VEGF) treatment strategies for wet age-related macular degeneration (wAMD) in a real-word setting in Japan. METHODS: Single-center, cross-sectional survey of caregivers of patients with wAMD performed in a hospital in Mito-City, a rural area in Japan. Caregiver burden was evaluated using the Burden Index of Caregivers (BIC-11), and depressive symptoms were assessed by the Center for Epidemiologic Studies Depression scale...
2017: PloS One
https://www.readbyqxmd.com/read/29196910/radiopharmaceutical-tracers-for-cardiac-imaging
#6
Osamu Manabe, Tatsuya Kikuchi, Arthur J H A Scholte, Mohammed El Mahdiui, Ryuichi Nishii, Ming-Rong Zhang, Eriko Suzuki, Keiichiro Yoshinaga
Cardiovascular disease (CVD) is the leading cause of death and disease burden worldwide. Nuclear myocardial perfusion imaging with either single-photon emission computed tomography or positron emission tomography has been used extensively to perform diagnosis, monitor therapies, and predict cardiovascular events. Several radiopharmaceutical tracers have recently been developed to evaluate CVD by targeting myocardial perfusion, metabolism, innervation, and inflammation. This article reviews old and newer used in nuclear cardiac imaging...
December 1, 2017: Journal of Nuclear Cardiology: Official Publication of the American Society of Nuclear Cardiology
https://www.readbyqxmd.com/read/29138514/changing-trends-in-the-prevalence-of-h-pylori-infection-in-japan-1908-2003-a-systematic-review-and-meta-regression-analysis-of-170-752-individuals
#7
Chaochen Wang, Takeshi Nishiyama, Shogo Kikuchi, Manami Inoue, Norie Sawada, Shoichiro Tsugane, Yingsong Lin
Changing trends in the prevalence of H. pylori infection in the general population over time are thought to be the main driving force behind the declining gastric cancer mortality in Japan. However, whether the prevalence of H. pylori infection itself shows a birth-cohort pattern needs to be corroborated. We performed a systematic review of studies that reported the prevalence of H. pylori infection among Japanese individuals. Meta-regression was conducted in the framework of a generalized additive mixed model (GAMM) to account for heterogeneity in the prevalence of H...
November 14, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29136221/facial-flushing-after-alcohol-intake-as-a-predictor-for-a-high-risk-of-synchronous-or-metachronous-cancer-of-the-upper-gastrointestinal-tract
#8
Hiroyuki Harada, Shogo Shinohara, Shinji Takebayashi, Masahiro Kikuchi, Keizo Fujiwara, Tetsuhiko Michida, Ryosuke Yamamoto, Kazuki Hayashi, Koji Saida, Yasushi Naito
Background: In Japan, there has been a lot of reports showing an association between facial flushing after light alcohol consumption and heterozygosity for inactive aldehyde dehydrogenase-2 (ALDH2). Persons with inactive ALDH2 may have a higher risk of alcohol-related oral, pharyngeal and esophageal cancers, compared with those with wild-type ALDH2. The purpose of this study was to examine whether flushers with oral or pharyngeal squamous cell carcinoma have an increased risk of synchronous or metachronous cancer of the upper gastrointestinal (UGI) tract...
November 9, 2017: Japanese Journal of Clinical Oncology
https://www.readbyqxmd.com/read/29132799/surgical-exploration-for-impalpable-testis-which-should-be-first-inguinal-exploration-or-laparoscopic-abdominal-exploration
#9
Akihiro Igarashi, Kenta Kikuchi, Kenjiro Ogushi, Mariko Hasegawa, Masahiro Hatanaka, Junko Fujino, Yoko Kishi, Hitoshi Ikeda
PURPOSE: To discuss an optimal surgical approach for impalpable testis in children, our own treatment results and those reported in the literature were reviewed. MATERIALS AND METHODS: Seventy-two impalpable testes were diagnosed in 68 patients: unilateral in 64 patients and bilateral in 4 patients. All patients underwent surgical exploration at the ages of 6 to 140months (median, 15months). The inguinal canal was initially explored, and abdominal exploration was performed with laparoscopy when an extra-abdominal testis was not identified...
October 16, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29119669/sinusitis-caused-by-exserohilum-rostratum-after-cord-blood-transplantation-for-myelodysplastic-syndrome-a-case-report-and-literature-review
#10
Sumiko Kohashi, Takaaki Toyama, Norisato Hashimoto, Masatoshi Sakurai, Jun Kato, Taku Kikuchi, Yuya Koda, Kayoko Sugita, Naoki Hasegawa, Kyoko Yarita, Katsuhiko Kamei, Shinichiro Okamoto, Takehiko Mori
Invasive fungal disease is a serious infectious complication of allogeneic hematopoietic stem cell transplantation (HSCT). Exserohilum rostratum is a species causing phaeohyphomycosis, which rarely causes invasive disease in humans. We treated a case of sinusitis caused by E. rostratum after cord blood transplantation (CBT). A 60-year-old man with myelodysplastic syndrome, who had a medical history of an operation to correct deviation of the nasal septum, developed sinusitis caused by E. rostratum under prolonged profound neutropenia after a second CBT because of the graft rejection of the first transplantation...
November 8, 2017: Transplant Infectious Disease: An Official Journal of the Transplantation Society
https://www.readbyqxmd.com/read/29080918/ultra-high-resolution-ct-angiography-of-the-artery-of-adamkiewicz-a-feasibility-study
#11
Kunihiro Yoshioka, Ryoichi Tanaka, Hidenobu Takagi, Yuta Ueyama, Kei Kikuchi, Takuya Chiba, Kazumasa Arakita, Joanne D Schuijf, Yasuo Saito
PURPOSE: Preoperative identification of the artery of Adamkiewicz can help prevent postoperative spinal cord injury following thoracic and thoracoabdominal aortic repair. Several studies have demonstrated the feasibility of evaluating the artery of Adamkiewicz using multi-detector row computed tomography (CT), but precise visualization remains a challenge. The present study was conducted to evaluate the usefulness of ultra-high-resolution CT for visualizing the artery of Adamkiewicz with a slice thickness of 0...
October 28, 2017: Neuroradiology
https://www.readbyqxmd.com/read/29080243/limaprost-or-pregabalin-preoperative-and-postoperative-medication-for-pain-due-to-lumbar-spinal-stenosis
#12
Yuji Kasukawa, Naohisa Miyakoshi, Takashi Kobayashi, Kazuma Kikuchi, Kunio Ebata, Noriyuki Ishikawa, Tetsuya Suzuki, Hiroshi Sasaki, Yuji Hatakeyama, Michio Hongo, Yoshinori Ishikawa, Daisuke Kudo, Toshiki Abe, Koichiro Okuyama, Tadato Kido, Mitsuho Chiba, Toyohito Segawa, Masazumi Suzuki, Takashi Mizutani, Ryota Kimura, Yuichi Ono, Jumpei Iida, Eiji Abe, Yoichi Shimada
PURPOSE: We aimed to evaluate the incidence of (and risk factors for) postoperative pregabalin and/or limaprost to treat persistent numbness and/or pain of the lower extremities after lumbar spinal stenosis (LSS) surgery. METHODS: Medical records of 329 patients (168 men, 161 women; average age 70 years) were retrospectively reviewed for data on the duration of LSS diagnosis; LSS disease; preoperative medication (limaprost, pregabalin, or combined limaprost/pregabalin; duration); symptoms; preoperative/postoperative intermittent claudication (IC); operation type; and postoperative medication and period...
October 27, 2017: Pain Practice: the Official Journal of World Institute of Pain
https://www.readbyqxmd.com/read/29076277/robotic-surgery-for-the-upper-gastrointestinal-tract-current-status-and-future-perspectives
#13
REVIEW
Masaya Nakauchi, Ichiro Uyama, Koichi Suda, Mohamed Mahran, Tetsuya Nakamura, Susumu Shibasaki, Kenji Kikuchi, Shinichi Kadoya, Kazuki Inaba
More than 4000 da Vinci Surgical Systems have been installed worldwide. Robotic surgery using the da Vinci Surgical System has been increasingly performed in the last decade, especially in urology and gynecology. The da Vinci Surgical System has not become standard in surgery of the upper gastrointestinal tract because of a lack of clear benefits in comparison with conventional minimally invasive surgery. We initiated robotic gastrectomy and esophagectomy for patients with upper gastrointestinal cancer in 2009, and we have demonstrated the potential advantages of the da Vinci Surgical System in reducing postoperative local complications after gastrectomy and recurrent laryngeal nerve palsy after esophagectomy...
November 2017: Asian Journal of Endoscopic Surgery
https://www.readbyqxmd.com/read/29061138/the-evidence-base-for-circulating-tumour-dna-blood-based-biomarkers-for-the-early-detection-of-cancer-a-systematic-mapping-review
#14
Ian A Cree, Lesley Uttley, Helen Buckley Woods, Hugh Kikuchi, Anne Reiman, Susan Harnan, Becky L Whiteman, Sian Taylor Philips, Michael Messenger, Angela Cox, Dawn Teare, Orla Sheils, Jacqui Shaw
BACKGROUND: The presence of circulating cell-free DNA from tumours in blood (ctDNA) is of major importance to those interested in early cancer detection, as well as to those wishing to monitor tumour progression or diagnose the presence of activating mutations to guide treatment. In 2014, the UK Early Cancer Detection Consortium undertook a systematic mapping review of the literature to identify blood-based biomarkers with potential for the development of a non-invasive blood test for cancer screening, and which identified this as a major area of interest...
October 23, 2017: BMC Cancer
https://www.readbyqxmd.com/read/29050748/pediatric-kikuchi-fujimoto-disease-a-clinicopathologic-study-and-the-therapeutic-effects-of-hydroxychloroquine
#15
Yung-Chih Lin, Hsiu-Hui Huang, Bao-Ren Nong, Po-Yen Liu, Ying-Yao Chen, Yung-Feng Huang, Yee-Hsuan Chiou, Herng-Sheng Lee
BACKGROUND: To investigate the clinical features of Kikuchi-Fujimoto disease (KFD) in children, and place an emphasis on the therapeutic effects of hydroxychloroquine as monotherapy. METHODS: We retrospectively reviewed the medical records of all children diagnosed with KFD during the period January 1992 to September 2016 at a tertiary medical center in Taiwan. RESULTS: 40 patients were histopathologically confirmed as KFD, and the mean age of the patients was 13...
September 29, 2017: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
https://www.readbyqxmd.com/read/28958728/time-to-development-of-ocular-syphilis-after-syphilis-infection
#16
Motoyuki Tsuboi, Takeshi Nishijima, Shigeko Yashiro, Katsuji Teruya, Yoshimi Kikuchi, Naomichi Katai, Hiroyuki Gatanaga, Shinichi Oka
To provide an estimate of the incubation period of ocular syphilis based on serology using both clinical data and stored serum samples, we retrospectively reviewed patients with HIV-1 infection who presented with ocular syphilis between August 1997 and July 2015 in a tertiary hospital in Japan. The incubation period of ocular syphilis was defined as the time from syphilis infection to the development of ocular symptoms due to ocular syphilis. During the study period, 20 patients were diagnosed with ocular syphilis and 8 patients were enrolled in the present study...
September 25, 2017: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
https://www.readbyqxmd.com/read/28955254/android-robot-mediated-mock-job-interview-sessions-for-young-adults-with-autism-spectrum-disorder-a-pilot-study
#17
Hirokazu Kumazaki, Zachary Warren, Blythe A Corbett, Yuichiro Yoshikawa, Yoshio Matsumoto, Haruhiro Higashida, Teruko Yuhi, Takashi Ikeda, Hiroshi Ishiguro, Mitsuru Kikuchi
The feasibility and preliminary efficacy of an android robot-mediated mock job interview training in terms of both bolstering self-confidence and reducing biological levels of stress in comparison to a psycho-educational approach human interview was assessed in a randomized study. Young adults (ages 18-25 years) with autism spectrum disorder (ASD) were randomized to participate either in a mock job interview training with our android robot system (n = 7) or a self-paced review of materials about job-interviewing skills (n = 8)...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28950713/literature-review-herbal-medicine-treatment-after-large-scale-disasters
#18
Shin Takayama, Soichiro Kaneko, Takehiro Numata, Tetsuharu Kamiya, Ryutaro Arita, Natsumi Saito, Akiko Kikuchi, Minoru Ohsawa, Yoshitaka Kohayagawa, Tadashi Ishii
Large-scale natural disasters, such as earthquakes, tsunamis, volcanic eruptions, and typhoons, occur worldwide. After the Great East Japan earthquake and tsunami, our medical support operation's experiences suggested that traditional medicine might be useful for treating the various symptoms of the survivors. However, little information is available regarding herbal medicine treatment in such situations. Considering that further disasters will occur, we performed a literature review and summarized the traditional medicine approaches for treatment after large-scale disasters...
2017: American Journal of Chinese Medicine
https://www.readbyqxmd.com/read/28931767/musical-instrument-associated-health-issues-and-their-management
#19
Kae Okoshi, Taro Minami, Masahiro Kikuchi, Yasuko Tomizawa
Playing musical instruments can bring joy to people, but can also cause a wide variety of health issues that range from mild disorders to potentially fatal conditions. Although sports medicine is an established medical subspecialty, relatively few studies have investigated the health issues associated with musical instruments. Here we present an overview of these health issues. These include infections due to microorganisms, allergic reactions, as well as mechanical injuries from sustained high pressures within the oral, mediastinal, thoracic, and abdominal cavities...
September 2017: Tohoku Journal of Experimental Medicine
https://www.readbyqxmd.com/read/28858911/less-invasive-coronary-artery-bypass-grafting-international-landscape-and-progress
#20
Keita Kikuchi, Makoto Mori
PURPOSE OF REVIEW: Less-invasive coronary artery bypass grafting (CABG) has evolved in multiple forms. Specifically noteworthy are recent technical refinement and reports of mid-term outcomes from well designed trials and observational studies in off-pump CABG, minimally invasive coronary artery bypass grafting (MICS CABG) and hybrid coronary revascularization (HCR). This review summarizes the historical evolution and recent development in less-invasive coronary artery bypass grafting...
November 2017: Current Opinion in Cardiology
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