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https://www.readbyqxmd.com/read/29791958/imaging-patterns-of-muscle-atrophy
#1
Marc-André Weber, Marcel Wolf, Mike P Wattjes
The role of muscle imaging in the diagnosis of inherited and acquired muscle diseases has gained clinical relevance. In particular, magnetic resonance imaging (MRI) is increasingly being used for diagnostic purposes, especially with its capability of whole-body musculature assessment. The assessment and quantification of muscle involvement in muscle diseases can be of diagnostic value by identifying a certain involvement pattern and thus narrowing the differential diagnosis and supporting the clinical diagnosis...
July 2018: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/29789707/the-natural-course-of-passive-tenodesis-grip-in-individuals-with-spinal-cord-injury-with-preserved-wrist-extension-power-but-paralyzed-fingers-and-thumbs
#2
Hae Yoon Jung, Jieun Lee, Hyung Ik Shin
STUDY DESIGN: Cross-sectional. OBJECTIVES: To investigate the natural course of passive tenodesis grip in individuals with spinal cord injury (SCI) with no experience of tenodesis splint application and the related factors for success of the grip. SETTING: Community-dwelling persons with chronic SCI in South Korea. METHODS: Individuals with cervical SCI with preserved wrist extensor power, but completely paralyzed fingers and thumbs, were recruited...
May 22, 2018: Spinal Cord
https://www.readbyqxmd.com/read/29789347/scaling-of-avian-bipedal-locomotion-reveals-independent-effects-of-body-mass-and-leg-posture-on-gait
#3
REVIEW
Monica A Daley, Aleksandra Birn-Jeffery
Birds provide an interesting opportunity to study the relationships between body size, limb morphology and bipedal locomotor function. Birds are ecologically diverse and span a large range of body size and limb proportions, yet all use their hindlimbs for bipedal terrestrial locomotion, for at least some part of their life history. Here, we review the scaling of avian striding bipedal gaits to explore how body mass and leg morphology influence walking and running. We collate literature data from 21 species, spanning a 2500× range in body mass from painted quail to ostriches...
May 22, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29789267/the-effect-of-lower-limb-occlusion-on-recovery-following-sprint-exercise-in-academy-rugby-players
#4
N Williams, M Russell, C J Cook, L P Kilduff
OBJECTIVES: The effects of vascular occlusion on recovery of physiological and neuromuscular markers over 24h, and hormonal reactivity to subsequent exercise were investigated. DESIGN: Counterbalanced, randomised, crossover. METHODS: Academy rugby players (n=24) completed six 50-m sprints (5-min inter-set recovery) before occlusion cuff application (thighs) and intermittent inflation to 171-266mmHg (Recovery) or 15mmHg (Con) for 12-min (two sets, 3-min repetitions, 3-min non-occluded reperfusion)...
March 3, 2018: Journal of Science and Medicine in Sport
https://www.readbyqxmd.com/read/29788859/female-judo-athletes-physical-test-performances-are-unrelated-to-technical-tactical-competition-skills
#5
Rafael L Kons, Juliano Dal Pupo, Jonathan Ache-Dias, Daniele Detanico
This study analyzed the relationship between generic and judo-specific physical test performances and technical-tactical competition performances among 19 female judo athletes. Participant data were gathered in two stages: (a) physical tests-countermovement jump (CMJ), handgrip strength, Special Judo Fitness Test and Judogi Grip Strength Test; and (b) match performances recorded for technical-tactical analysis. Pearson's linear correlation and multiple linear regression analysis showed no significant correlations between any technical-tactical parameter and judo-specific physical tests...
January 1, 2018: Perceptual and Motor Skills
https://www.readbyqxmd.com/read/29787482/physical-performance-in-relation-to-menopause-status-and-physical-activity
#6
Dmitriy Bondarev, Eija K Laakkonen, Taija Finni, Katja Kokko, Urho M Kujala, Pauliina Aukee, Vuokko Kovanen, Sarianna Sipilä
OBJECTIVE: The aim of this study was to examine differences in physical performance (muscle power, muscle strength, aerobic capacity, and walking speed) across menopausal stages and potential of leisure physical activity (PA) to modify the impact of menopause on physical performance. METHODS: In this cross-sectional study, women aged 47 to 55 were randomly selected from the Finnish National Registry and categorized as premenopausal (n = 233), perimenopausal (n = 381), or postmenopausal (n = 299) based on serum concentrations of follicle-stimulating hormone and bleeding diary...
May 21, 2018: Menopause: the Journal of the North American Menopause Society
https://www.readbyqxmd.com/read/29786683/-the-application-of-kinesiotaping-for-the-rehabilitation-of-the-post-stroke-patients
#7
V I Berezutsky
This review of the scientific literature was designed to consider the prospects for the application of kinesiotaping for the rehabilitation of the post-stroke patients. The relevance of the work arises from the absence of a systemic analysis of the large number of investigations that have been carried out during the past two years. The objective of the present review article was to evaluate the influence of kinesiotaping on the health status of the post-stroke patients and the course of their rehabilitative treatment based on the results of analysis of the scientific reports published during the period from 2015 to 2017...
May 21, 2018: Voprosy Kurortologii, Fizioterapii, i Lechebnoĭ Fizicheskoĭ Kultury
https://www.readbyqxmd.com/read/29786625/differences-in-glenohumeral-joint-rotation-and-peak-power-output-between-super-league-and-championship-rugby-league-players
#8
Matthew R Haines
Haines, MR. Differences in glenohumeral joint rotation and peak power output between Super League and Championship Rugby League players. J Strength Cond Res 32(6): 1685-1691, 2018-Rugby league is a high-intensity sport with large impact forces sustained during play, resulting in high prevalence of shoulder injury. Consequently, shoulder strength and player power are important considerations for injury prevention and performance. Additionally, professional teams regularly compete against semiprofessional teams, where differences in physical conditioning could be marked...
June 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29785670/polymorphic-imprinting-of-slc38a4-gene-in-bovine-placenta
#9
Da Xu, Cui Zhang, Junliang Li, Guannan Wang, Weina Chen, Dongjie Li, Shijie Li
Imprinted genes are characterized by monoallelic expression that is dependent on parental origin. Comparative analysis of imprinted genes between species is a powerful tool for understanding the biological significance of genomic imprinting. The slc38a4 gene encodes a neutral amino acid transporter and is identified as imprinted in mice. In this study, the imprinting status of SLC38A4 was assessed in bovine adult tissues and placenta using a polymorphism-based approach. Results indicate that SLC38A4 is not imprinted in eight adult bovine tissues including heart, liver, spleen, lung, kidney, muscle, fat, and brain...
May 21, 2018: Biochemical Genetics
https://www.readbyqxmd.com/read/29784354/a-comparative-study-of-sterically-and-electro-statically-stabilized-silver-nanoparticles-for-the-determination-of-muscle-relaxant-tizanidine-insights-of-localized-surface-plasmon-resonance-surface-enhanced-raman-spectroscopy-and-electrocatalytic-activity
#10
Marwa R El-Zahry
A comparative study of two types of silver nanoparticles was investigated. The effect of the surface chemistry of the studied silver nanoparticles (AgNPs) on their localized surface plasmon resonance was utilized for the quantitative determination of muscle relaxant tizanidine drug. The studied AgNPs are classified according to the type of stabilizing agent used in their synthesis into electrostatically and sterically stabilized AgNPs. The electrostatically-stabilized AgNPs (AA AgNPs) were prepared using ascorbic acid as both reducing and protective agents in alkaline medium...
August 15, 2018: Talanta
https://www.readbyqxmd.com/read/29781940/alpha-actinin-3-r577x-polymorphism-influences-muscle-damage-and-hormonal-responses-after-a-soccer-game
#11
Daniel B Coelho, Eduardo M Pimenta, Izinara C Rosse, Christiano Veneroso, Guilherme De Azambuja Pussieldi, Lenice K Becker, Emerson C Oliveira, Maria R S Carvalho, Emerson Silami-Garcia
Coelho, DB, Pimenta, EM, Rosse, IC, Veneroso, C, Pussieldi, GDA, Becker, LK, De Oliveira, EC, Carvalho, MRS, and Silami-Garcia, E. Alpha-actinin-3 R577X polymorphism influences muscle damage and hormonal responses after a soccer game. J Strength Cond Res XX(X): 000-000, 2018-The purpose of this study was to evaluate indicators of muscle damage and hormonal responses after soccer matches and its relation to alpha-actinin-3 (ACTN3) gene expression (XX vs. RR/RX), considering that the R allele produces alpha-actinin-3 and provides greater muscle strength and power...
May 17, 2018: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/29781931/ultrasound-assessment-of-ice-ball-formation-by-cryoneurolysis-device-in-an-ex-vivo-model
#12
Adrian Kastler, Hannes Gruber, Elke Gizewski, Alexander Loizides
BACKGROUND AND OBJECTIVES: Real-time ice-ball formation during cryoneurolysis has sparsely been assessed with ultrasound (US). Cryoneurolysis in lower back pain syndrome represents a validated management option in cases of facet joint syndrome. Ultrasound may be a useful tool to perform facet joint cryodenervation. The objective of this study was to assess, ex vivo, the ability of US to assess the ice-ball formation of a cryoneurolysis device. METHODS: Ultrasound assessment of the ice-ball depiction was done using chicken muscle at 22°C in which several freezing cycles were performed with both 2...
May 17, 2018: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29781118/ballistic-tongue-projection-in-a-miniaturized-salamander
#13
Stephen M Deban, Segall V Bloom
Miniaturization of body size is often accompanied by peculiarities in morphology that can have functional consequences. We examined the feeding behavior and morphology of the miniaturized plethodontid salamander Thorius, one of the smallest vertebrates, to determine if its performance and biomechanics differ from those of its larger relatives. High-speed imaging and dynamics analysis of feeding at a range of temperatures show that tongue projection in Thorius macdougalli is ballistic and achieves accelerations of up to 600 G with low thermal sensitivity, indicating that tongue projection is powered by an elastic-recoil mechanism...
May 20, 2018: Journal of Experimental Zoology. Part A, Ecological and Integrative Physiology
https://www.readbyqxmd.com/read/29776013/prognostic-pathologic-factors-in-radical-cystectomy-after-neoadjuvant-chemotherapy
#14
Fadi Brimo, Michelle R Downes, Tamara Jamaspishvili, David Berman, Guliz A Barkan, Daniel Athanazio, Schuharazad Abro, Kash Visram, Asli Yilmaz, Shraddha Solanki, Elan Hahn, Robert Siemens, Wassim Kassouf, Kiril Trpkov
We undertook a systematic evaluation of the prognostic value of numerous histologic factors in 165 radical cystectomies (RC) of patients with invasive urothelial carcinoma who underwent surgery after neoadjuvant chemotherapy (NAC). Tumor regression grade (TRG) and therapy-related stromal and epithelial changes were also recorded. Locally advanced disease (≥pT2 and/or pN+) was present in 64% of patients, 22% had no evidence of residual carcinoma (pT0+pN0) and 28% had no evidence of residual muscle invasive carcinoma (≤pT1+N0)...
May 18, 2018: Histopathology
https://www.readbyqxmd.com/read/29774175/motor-interconnections-between-superior-and-inferior-laryngeal-nerves
#15
Emin Gurleyik
Introduction Anatomical studies on human cadavers have established anastomoses between laryngeal nerves. However, we need to functionally identify motor communication via these anastomoses between the recurrent laryngeal nerve (RLN) and the external branch of the superior laryngeal nerve (EBSLN) in living bodies. We aim to establish motor interconnections using intraoperative nerve monitoring (IONM). Methods IONM of 112 EBSLNs and RLNs in 62 thyroidectomy cases was used to establish motor functions of laryngeal nerves...
March 16, 2018: Curēus
https://www.readbyqxmd.com/read/29773685/simulated-work-loops-predict-maximal-human-cycling-power
#16
James C Martin, Jennifer A Nichols
Fish, birds, and lizards sometimes perform locomotor activities with maximized muscle power. Whether humans maximize muscular power is unknown because current experimental techniques cannot be applied non-invasively. This study uses simulated muscle work loops to examine whether voluntary maximal cycling is characterized by maximized muscle power. The simulated work loops leverage experimentally measured joint angles, anatomically realistic muscle parameters (muscle-tendon lengths, velocities, and moment arms), and a published muscle model to calculate powers and forces for thirty-eight muscles...
May 17, 2018: Journal of Experimental Biology
https://www.readbyqxmd.com/read/29773272/juvenile-dermatomyositis-latest-advances
#17
REVIEW
Qiong Wu, Lucy R Wedderburn, Liza J McCann
Registries and biobanks for juvenile dermatomyositis (JDM) have generated statistical power to help understand pathogenesis and determine treatment and long-term outcomes in this rare and heterogeneous disease. Genotype, autoantibodies, muscle histology and early clinical features may predict prognosis and guide personalised treatment. While corticosteroids and disease-modifying anti-rheumatic drugs improve outcomes, there remain children who experience refractory disease. Ongoing research into the aberrant immune response and novel biological targets is necessary...
August 2017: Best Practice & Research. Clinical Rheumatology
https://www.readbyqxmd.com/read/29771823/residual-force-enhancement-is-attenuated-in-a-shortening-magnitude-dependent-manner
#18
Atsuki Fukutani, Walter Herzog
INTRODUCTION: The isometric force attained after active stretch is greater than that attained in a purely isometric contraction. This property is referred to as residual force enhancement (RFE). Although RFE is thought to contribute to the enhanced force and power in stretch-shortening cycles (SSCs), it is unclear whether shortening that occurs after active stretch eliminates the RFE induced by active stretch. Therefore, we evaluated the influence of shortening on RFE. METHODS: Skinned rabbit soleus fibers (N = 43) were used for all tests...
May 16, 2018: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/29771627/efficiency-and-perceived-exertion-of-novel-wheelchair-wheels-a-comparative-study
#19
Laura Sanches Rocha, Bonita Sawatzky, W Ben Mortenson
New geared wheelchair wheels have been developed allowing the user to pull backwards on the rims to move forward. Theoretically, this utilizes larger muscle groups compared to conventional propulsion preventing repetitive stress injuries. This study compared the gross mechanical efficiency (GME), perceived effort and energy expenditure of propelling the wheelchair using two types of these geared wheels and standard forward propulsion wheels. A within participants repeated measures design was used. Participants' energy expenditure and perceived exertion were measured...
May 17, 2018: Assistive Technology: the Official Journal of RESNA
https://www.readbyqxmd.com/read/29771317/exon-skipping-advances-for-duchenne-muscular-dystrophy
#20
Lucía Echevarría, Philippine Aupy, Aurélie Goyenvalle
Duchenne muscular dystrophy (DMD) is a fatal genetic disorder characterized by progressive muscle wasting that has currently no cure. Exon-skipping strategy represents one of the most promising therapeutic approaches that aims to restore expression of a shorter but functional dystrophin protein. The antisense field has remarkably progress over the last years with recent accelerated approval of the first ASO-based therapy for DMD, Exondys 51, though the therapeutic benefit remains to be proven in patients. Despite clinical advances, the poor effective delivery to target all muscle remains the main hurdle for antisense drug therapy...
May 16, 2018: Human Molecular Genetics
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