keyword
MENU ▼
Read by QxMD icon Read
search

Falcon

keyword
https://www.readbyqxmd.com/read/28428604/in-vitro-cavity-and-crown-preparations-and-direct-restorations-a-comparison-of-performance-at-the-start-and-end-of-the-fd-programme
#1
F J T Burke, V Ravaghi, L Mackenzie, N Priest, H C Falcon
Aim To assess the performance and thereby the progress of the FDs when they carried out a number of simulated clinical exercises at the start and at the end of their FD year.Methods A standardised simulated clinical restorative dentistry training exercise was carried out by a group of 61 recently qualified dental graduates undertaking a 12 months' duration foundation training programme in England, at both the start and end of the programme. Participants completed a Class II cavity preparation and amalgam restoration, a Class IV composite resin restoration and two preparations for a porcelain-metal full crown...
April 21, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28427546/is-the-bronchodilator-test-an-useful-tool-to-measure-asthma-control
#2
Marta Ferrer Galván, Francisco Javier Alvarez Gutiérrez, Auxiliadora Romero Falcón, Beatriz Romero Romero, Antonia Sáez, Juan Francisco Medina Gallardo
INTRODUCTION: Asthma control includes the control of symptoms and future risk. We sought to evaluate the usefulness of the degree of spirometric reversibility of the forced expiratory volume in one second (FEV1) as the target parameter of control. METHODOLOGY: Patients with bronchial asthma were followed up for one year. The clinical, functional, inflammatory and control parameters of the asthma were collected. The area under the curve (AUC) was estimated to establish the cutoff point of the post-bronchodilator FEV1 reversibility in relation to non-control asthma...
May 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/28427021/risk-factors-for-learning-problems-in-youth-with-psychogenic-non-epileptic-seizures
#3
Julia Doss, Rochelle Caplan, Prabha Siddarth, Brenda Bursch, Tatiana Falcone, Marcy Forgey, Kyle Hinman, W Curt LaFrance, Rebecca Laptook, Richard Shaw, Deborah Weisbrot, Matthew Willis, Sigita Plioplys
OBJECTIVES: This study examined the risk factors for learning problems (LP) in pediatric psychogenic non-epileptic seizures (PNES) and their specificity by comparing psychopathology, medical, cognitive/linguistic/achievement, bullying history, and parent education variables between subjects with PNES with and without LP and between subjects with PNES and siblings with LP. METHODS: 55 subjects with PNES and 35 siblings, aged 8-18years, underwent cognitive, linguistic, and achievement testing, and completed somatization and anxiety sensitivity questionnaires...
April 17, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28422821/how-the-cognitive-reserve-interacts-with-%C3%AE-amyloid-deposition-in-mitigating-fdg-metabolism-an-observational-study
#4
Elena Carapelle, Laura Serra, Sergio Modoni, Michele Falcone, Carlo Caltagirone, Marco Bozzali, Luigi Maria Specchio, Carlo Avolio
This observational study had the aim to assess the interaction between cognitive reserve (CR) and cerebrospinal fluid β-amyloid1-42 (Aβ1-42) in modulating brain [18F]fluorodeoxyglucose positron emission tomography (FDG-PET) metabolism in patients with moderate Alzheimer disease (AD).Twenty-seven patients with probable AD and 25 neurological normal subjects (NNS) entered the study. All participants had an FDG-PET scan, and AD patients also received a lumbar puncture to measure Aβ1-42, 181p-tau, and Tau concentrations...
April 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28422556/the-acute-effects-of-breaking-up-seated-office-work-with-standing-or-light-intensity-walking-on-interstitial-glucose-concentration-a-randomised-crossover-trial
#5
Laura A Brocklebank, Rob C Andrews, Angie Page, Catherine L Falconer, Sam Leary, Ashley Cooper
BACKGROUND: The aim of this randomised, three-period, three-treatment crossover trial was to examine the acute effects of regularly breaking up seated office work with short bouts of standing or light-intensity walking on postprandial interstitial glucose concentration. METHODS: Seventeen middle-aged office workers performed three five-hour trial conditions at their workplace in a random order: 1) uninterrupted sitting; 2) sitting interrupted by two minutes of standing every 20 minutes; and 3) sitting interrupted by two minutes of light-intensity walking every 20 minutes...
April 19, 2017: Journal of Physical Activity & Health
https://www.readbyqxmd.com/read/28421062/identification-of-rare-pb2-d701n-mutation-from-a-patient-with-severe-influenza-contribution-of-the-pb2-d701n-mutation-to-the-pathogenicity-of-human-influenza
#6
Amelia Nieto, Francisco Pozo, Matxalen Vidal-García, Manuel Omeñaca, Inmaculada Casas, Ana Falcón
Several amino acid changes have been previously implicated in adaptation of avian influenza viruses to human hosts, among them the D701N change in the PB2 polymerase subunit that also is the main determinant of avian virus pathogenesis in animal models. However, previous studies using recombinant viruses did not provide conclusive information of the contribution of this PB2 residue to pathogenicity in human influenza virus strains. We identified this mutation in an A(H1N1)pdm09-like human influenza virus isolated from an infected patient with pneumonia and acute respiratory failure, admitted to the intensive care unit...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28414610/clinical-calculator-for-early-mortality-in-metastatic-colorectal-cancer-an-analysis-of-patients-from-28-clinical-trials-in-the-aide-et-recherche-en-canc%C3%A3-rologie-digestive-database
#7
Lindsay A Renfro, Richard M Goldberg, Axel Grothey, Alberto Sobrero, Richard Adams, Matthew T Seymour, Volker Heinemann, Hans-Joachim Schmoll, Jean-Yves Douillard, Herbert Hurwitz, Charles S Fuchs, Eduardo Diaz-Rubio, Rainer Porschen, Christophe Tournigand, Benoist Chibaudel, Paulo M Hoff, Fairooz F Kabbinavar, Alfredo Falcone, Niall C Tebbutt, Cornelis J A Punt, J Randolph Hecht, John Souglakos, Carsten Bokemeyer, Eric Van Cutsem, Leonard Saltz, Aimery de Gramont, Daniel J Sargent
Purpose Factors contributing to early mortality after initiation of treatment of metastatic colorectal cancer are poorly understood. Materials and Methods Data from 22,654 patients enrolled in 28 randomized phase III trials contained in the ARCAD (Aide et Recherche en Cancérologie Digestive) database were pooled. Multivariable logistic regression models for 30-, 60-, and 90-day mortality were constructed, including clinically and statistically significant patient and disease factors and interaction terms. A calculator (nomogram) for 90-day mortality was developed and validated internally using bootstrapping methods and externally using a 10% random holdout sample from each trial...
April 17, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28409970/observation-of-betatron-x-ray-radiation-in-a-self-modulated-laser-wakefield-accelerator-driven-with-picosecond-laser-pulses
#8
F Albert, N Lemos, J L Shaw, B B Pollock, C Goyon, W Schumaker, A M Saunders, K A Marsh, A Pak, J E Ralph, J L Martins, L D Amorim, R W Falcone, S H Glenzer, J D Moody, C Joshi
We investigate a new regime for betatron x-ray emission that utilizes kilojoule-class picosecond lasers to drive wakes in plasmas. When such laser pulses with intensities of ∼5×10^{18}  W/cm^{2} are focused into plasmas with electron densities of ∼1×10^{19}  cm^{-3}, they undergo self-modulation and channeling, which accelerates electrons up to 200 MeV energies and causes those electrons to emit x rays. The measured x-ray spectra are fit with a synchrotron spectrum with a critical energy of 10-20 keV, and 2D particle-in-cell simulations were used to model the acceleration and radiation of the electrons in our experimental conditions...
March 31, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/28399947/survival-of-macrobrachium-amazonicum-embryos-submitted-to-cooling
#9
Arthur Vinícius Lourenço Ferreira, Moisés Fernandes Martins, Míriam Luzia Nogueira Martins de Sousa, Aldeney Andrade Soares Filho, Célia Maria de Souza Sampaio
Cooling techniques have several applications for reproduction in aquaculture. However, few studies have sought to create protocols for cooling and cryopreservation of Macrobrachium amazonicum embryos. Thus, the objective of this work was to verify the survival of M. amazonicum embryos and the correlation between embryonic volume and mortality of M. amazonicum embryos after cooling. Embryo pools were collected from three females and divided into two treatment groups: dimethyl sulfoxide (DMSO) 3% and ethylene glycol (EG) 0...
April 12, 2017: Zygote: the Biology of Gametes and Early Embryos
https://www.readbyqxmd.com/read/28395257/life-cycle-tools-combined-with-multi-criteria-and-participatory-methods-for-agricultural-sustainability-insights-from-a-systematic-and-critical-review
#10
REVIEW
Anna Irene De Luca, Nathalie Iofrida, Pekka Leskinen, Teodora Stillitano, Giacomo Falcone, Alfio Strano, Giovanni Gulisano
Life cycle (LC) methodologies have attracted a great interest in agricultural sustainability assessments, even if, at the same time, they have sometimes been criticized for making unrealistic assumptions and subjective choices. To cope with these weaknesses, Multi-Criteria Decision Analysis (MCDA) and/or participatory methods can be used to balance and integrate different sustainability dimensions. The purpose of this study is to highlight how life cycle approaches were combined with MCDA and participatory methods to address agricultural sustainability in the published scientific literature...
April 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28381226/annurca-apple-m-pumila-miller-cv-annurca-extracts-act-against-stress-and-ageing-in-s-cerevisiae-yeast-cells
#11
Mariarita Stirpe, Vanessa Palermo, Michele Maria Bianchi, Romano Silvestri, Claudio Falcone, Giancarlo Tenore, Ettore Novellino, Cristina Mazzoni
BACKGROUND: During the past years, a number of studies have demonstrated the positive effect of apple on ageing and different diseases such as cancer, degenerative and cardiovascular diseases. The unicellular yeast Saccharomyces cerevisiae represents a simple eukaryotic model to study the effects of different compounds on lifespan. We previously demonstrated that apple extracts have anti-ageing effects in this organism because of their antioxidant properties. In particular, the effect is related to the presence in this fruit of polyphenols, which give a large contribution to the antioxidant activity of apples...
April 5, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28380517/surface-wetting-strategy-prevents-acute-heat-exposure-induced-alterations-of-hypothalamic-stress-and-metabolic-related-genes-in-broiler-chickens
#12
H Rajaei-Sharifabadi, E Greene, A Piekarski, D Falcon, L Ellestad, A Donoghue, W Bottje, T Porter, Y Liang, S Dridi
Heat stress (HS) is devastating to poultry production worldwide, yet its biology and molecular responses are not well defined. Although advances in management strategy have partially alleviated the negative impact of HS, productivity still continues to decline when the ambient temperature rises. Therefore, identifying mechanism-based approaches to decrease HS susceptibility while improving production traits is critical. Recently, we made a breakthrough by applying a surface wetting strategy and showing that it improves growth performance compared with the current conventional cooling system...
March 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28369940/single-nucleotide-polymorphisms-in-the-igf-irs-pathway-are-associated-with-outcome-in-mcrc-patients-enrolled-in-the-fire-3-trial
#13
Marta Schirripa, Wu Zhang, Volker Heinemann, Shu Cao, Satoshi Okazaki, Dongyun Yang, Fotios Loupakis, Martin D Berger, Yan Ning, Yuji Miyamoto, Mitsukuni Suenaga, Roel F Gopez, Jordan D West, Diana Hanna, Afsaneh Barzi, Alfredo Falcone, Sebastian Stintzing, Heinz-Josef Lenz
The Insulin-like growth factor (IGF)/IGF-receptor pathway with its scaffolding proteins Insulin Receptor Substrate (IRS)1 and IRS2 are crucial regulators of metabolism and progression in metastatic colorectal cancer (mCRC). The goal of the study was the identification of predictive and prognostic markers among IRS1, IRS2, IGF1 and IGF-1R SNPs in mCRC patients enrolled in the FIRE-3 trial. Four SNPs of IRS (IRS1 rs1801278, rs1801123; IRS2 rs1805097, rs2289046) and 4 SNPs of IGF1-IGFR1 (rs6214, rs6220, rs2946834, rs2016347) were analyzed by PCR/direct-sequencing in the FIRE-3 trial...
April 1, 2017: International Journal of Cancer. Journal International du Cancer
https://www.readbyqxmd.com/read/28367749/improving-voluntary-medical-male-circumcision-standards-adherence-and-post-procedure-follow-up-in-uganda-a-mixed-methods-study
#14
Sarah Smith Lunsford, John Byabagambi, Zachariah Falconer-Stout, Esther Karamagi
Voluntary medical male circumcision (VMMC) has been demonstrated to reduce the transmission of HIV by 60%. Scaling up VMMC services requires that they be of high quality, socially accepted, and effective. We evaluated an intervention aimed at improving VMMC standards adherence and patient follow-up rates in nine facilities in Uganda. We also qualitatively explored why some men return for follow-up care and others do not. The completeness and quality of clinical documentation was poor at baseline, but significantly improved at endline...
March 2017: African Journal of AIDS Research: AJAR
https://www.readbyqxmd.com/read/28361804/risk-adjusted-mortality-after-hip-replacement-surgery-a-retrospective-study
#15
Gabriele Messina, Silvia Forni, Daniele Rosadini, Manuele Falcone, Francesca Collini, Nicola Nante
INTRODUCTION: Hip replacement (HR) operations are increasing. Short term mortality is an indicator of quality; few studies include risk adjustment models to predict HR outcomes. We evaluated in-hospital and 30-day mortality in hospitalized patients for HR and compared the performance of two risk adjustment algorithms. MATERIALS AND METHODS: A retrospective cohort study on hospital discharge records of patients undergoing HR from 2000 to 2005 in Tuscany Region, Italy, applied All-Patient Refined Diagnosis Related Groups (APR-DRG) and Elixhauser Index (EI) risk adjustment models to predict outcomes...
January 2017: Annali Dell'Istituto Superiore di Sanità
https://www.readbyqxmd.com/read/28358612/management-and-case-outcome-of-gastric-impaction-in-four-raptors-a-case-series
#16
Jeffrey R Applegate, Arnaud Van Wettere, Emily F Christiansen, Laurel A Degernes
Four captive raptors, an American kestrel ( Falco sparverius ), peregrine falcon ( Falco peregrinus ), golden eagle ( Aquila chrysaetos ), and barn owl ( Tyto alba ), were diagnosed with ventricular and/or proventricular foreign material impactions consisting of artificial turf substrate, paper and plastic substrate, grass, and newspaper. Partial or total anorexia was reported in all birds and decreased casting in 2 birds. Survey radiographs confirmed presence of gastric enlargement in all 4 birds. The kestrel and eagle were treated unsuccessfully with gastroscopy and gastric lavage, respectively, followed by surgical intervention to remove the ventricular impactions...
March 2017: Journal of Avian Medicine and Surgery
https://www.readbyqxmd.com/read/28353351/effects-of-human-umbilical-cord-blood-mononuclear-cells-on-respiratory-system-mechanics-in-a-murine-model-of-neonatal-lung-injury
#17
David R Mills, Quanfu Mao, Sharon Chu, Kate Falcon Girard, Morey Kraus, James F Padbury, Monique E De Paepe
BACKGROUND: Mononuclear cells (MNCs) have well-documented beneficial effects in a wide range of adult pulmonary diseases. The effects of human umbilical cord blood-derived MNCs on neonatal lung injury, highly relevant for potential autologous application in preterm newborns at risk for bronchopulmonary dysplasia (BPD), remain incompletely established. The aim of this study was to determine the long-term morphologic and functional effects of systemically delivered MNCs in a murine model of neonatal lung injury...
March 29, 2017: Experimental Lung Research
https://www.readbyqxmd.com/read/28347919/autophagy-related-polymorphisms-predict-hypertension-in-patients-with-metastatic-colorectal-cancer-treated-with-folfiri-and-bevacizumab-results-from-tribe-and-fire-3-trials
#18
Martin D Berger, Shinichi Yamauchi, Shu Cao, Diana L Hanna, Yu Sunakawa, Marta Schirripa, Satoshi Matsusaka, Dongyun Yang, Susan Groshen, Wu Zhang, Yan Ning, Satoshi Okazaki, Yuji Miyamoto, Mitsukuni Suenaga, Sara Lonardi, Chiara Cremolini, Alfredo Falcone, Volker Heinemann, Fotios Loupakis, Sebastian Stintzing, Heinz-Josef Lenz
PURPOSE: The most frequent bevacizumab-related side-effects are hypertension, proteinuria, bleeding and thromboembolism. To date, there is no biomarker that predicts anti-VEGF-associated toxicity. As autophagy inhibits angiogenesis, we hypothesised that single-nucleotide polymorphisms (SNPs) within autophagy-related genes may predict bevacizumab-mediated toxicity in patients with metastatic colorectal cancer (mCRC). PATIENTS AND METHODS: Patients with mCRC treated with first-line FOLFIRI and bevacizumab in two phase III randomised trials, namely the TRIBE trial (n = 219, discovery cohort) and the FIRE-3 trial (n = 234, validation cohort) were included in this study...
March 24, 2017: European Journal of Cancer
https://www.readbyqxmd.com/read/28347705/impact-of-temperature-on-sea-bass-dicentrarchus-labrax-retina-fatty-acid-composition-expression-of-rhodopsin-and-enzymes-of-lipid-and-melatonin-metabolism
#19
Mehdi Bouaziz, Safa Bejaoui, Imen Rabeh, Raouf Besbes, M 'Hamed El Cafsi, Jack Falcon
Teleost fish are ectothermic vertebrates. Their metabolism, physiology and behavior rely on the external temperature. This study, on the retina of the sea bass Dicentrarchus labrax, reports on the impact of temperature on the fatty acid composition and mRNA abundance of key enzymes of lipid metabolism: fatty acid desaturase-2 (FADS2), fatty acid elongase-5 (ELOVL5), sterol regulatory element-binding protein-1 (SREBP-1), triglyceride lipase and phospholipase A2 (PLA2). We also report on the effects on the photopigment molecule rhodopsin and on enzymes of the melatonin synthesis pathway, namely arylalkylamine N-acetyltransferases 1a and 1b and acetylserotonin methyltransferase...
March 27, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28344857/metastatic-braf-k601e-mutated-melanoma-reaches-complete-response-to-mek-inhibitor-trametinib-administered-for-over-36%C3%A2-months
#20
Riccardo Marconcini, Luca Galli, Andrea Antonuzzo, Simona Bursi, Claudia Roncella, Gabriella Fontanini, Elisa Sensi, Alfredo Falcone
BACKGROUND: The BRAF K601E mutation occurs in 5% of patients with melanoma, and is the third most common type of BRAF mutation. However, treatment with BRAF and mitogen-activated extracellular signal-regulated kinase (MEK) inhibitors is only approved in patients with BRAF V600-positive melanoma, and patients with K601E-mutated melanoma do not have access to such drugs. CASE PRESENTATION: A female patient was diagnosed with high tumor burden metastatic melanoma harboring the BRAF K601E mutation...
2017: Experimental Hematology & Oncology
keyword
keyword
50279
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"