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https://www.readbyqxmd.com/read/28803768/assessment-of-preoperative-anxiety-in-cardiac-surgery-patients-lacking-a-history-of-anxiety-contributing-factors-and-postoperative-morbidity
#1
Joaquín Hernández-Palazón, Diego Fuentes-García, Luis Falcón-Araña, María José Roca-Calvo, Sebastián Burguillos-López, Paloma Doménech-Asensi, Rubén Jara-Rubio
OBJECTIVES: The aim of this study was to measure the level of preoperative anxiety in patients scheduled for cardiac surgery, identify any influencing clinical factors, and assess the relationship between anxiety and postoperative morbidity. DESIGN: A prospective and consecutive study. SETTING: A single university hospital. PARTICIPANTS: The study comprised 200 patients scheduled for cardiac surgery. INTERVENTIONS: Each patient was asked to grade his or her preoperative anxiety level using the Visual Analogue Scale for Anxiety, Amsterdam Preoperative Anxiety and Information Scale, and set of specific anxiety-related questions...
April 26, 2017: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/28801547/early-changes-in-plasma-dna-levels-of-mutant-kras-as-a-sensitive-marker-of-response-to-chemotherapy-in-pancreatic-cancer
#2
Marzia Del Re, Caterina Vivaldi, Eleonora Rofi, Enrico Vasile, Mario Miccoli, Chiara Caparello, Paolo Davide d'Arienzo, Lorenzo Fornaro, Alfredo Falcone, Romano Danesi
Pancreatic cancer (PDAC) is still lacking of reliable markers to monitor tumor response. CA 19-9 is the only biomarker approved, despite it has several limitations in sensitivity and specificity. Since mutations of KRAS occur in more than 90% of tumors, its detection in circulating free tumor DNA (cftDNA) could represent a biomarker to monitor chemotherapy response. Twenty-seven advanced PDAC patients given first-line 5-fluorouracil, irinotecan and oxaliplatin or gemcitabine and nab-paclitaxel were enrolled...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28800646/heritability-of-retinal-vascular-fractals-a-twin-study
#3
Anna Stage Vergmann, Rebecca Broe, Line Kessel, Jesper Leth Hougaard, Sören Möller, Kirsten Ohm Kyvik, Michael Larsen, Inger Christine Munch, Jakob Grauslund
Purpose: To determine the genetic contribution to the pattern of retinal vascular branching expressed by its fractal dimension. Methods: This was a cross-sectional study of 50 monozygotic and 49 dizygotic, same-sex twin pairs aged 20 to 46 years. In 50°, disc-centered fundus photographs, the retinal vascular fractal dimension was measured using the box-counting method and compared within monozygotic and dizygotic twin pairs using Pearson correlation coefficients...
August 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28799949/quantifying-the-effects-of-prior-acetyl-salicylic-acid-on-sepsis-related-deaths-an-individual-patient-data-meta-analysis-using-propensity-matching
#4
James Trauer, Stephen Muhi, Emma S McBryde, Shmeylan A Al Harbi, Yaseen M Arabi, Andrew J Boyle, Rodrigo Cartin-Ceba, Wei Chen, Yung-Tai Chen, Marco Falcone, Ognjen Gajic, Jack Godsell, Michelle Ng Gong, Daryl Kor, Wolfgang Lösche, Daniel F McAuley, Hollis R O'Neal, Michael Osthoff, Gordon P Otto, Maik Sossdorf, Min-Juei Tsai, Juan C Valerio-Rojas, Tom van der Poll, Francesco Violi, Lorraine Ware, Andreas F Widmer, Maryse A Wiewel, Johannes Winning, Damon P Eisen
OBJECTIVE: The primary objective was to conduct a meta-analysis on published observational cohort data describing the association between acetyl-salicylic acid (aspirin) use prior to the onset of sepsis and mortality in hospitalized patients. STUDY SELECTION: Studies that reported mortality in patients on aspirin with sepsis with a comparison group of patients with sepsis not on prior aspirin therapy were included. DATA SOURCES: Fifteen studies described hospital-based cohorts (n = 17,065), whereas one was a large insurance-based database (n = 683,421)...
August 9, 2017: Critical Care Medicine
https://www.readbyqxmd.com/read/28799634/effectiveness-of-highly-purified-urofollitropin-treatment-in-patients-with-idiopathic-azoospermia-before-testicular-sperm-extraction
#5
Andrea Cocci, Gianmartin Cito, Giorgio I Russo, Marco Falcone, Marco Capece, Massimiliano Timpano, Pier Andrea Della Camera, Simone Morselli, Giovanni Tasso, Girolamo Morelli, Giuseppe Morgia, Andrea Minervini, Sergio Serni, Marco Carini, Alessandro Natali, Mauro Gacci
INTRODUCTION: Recent evidences demonstrated that male factor alone is responsible for about 30% cases of infertility. Human follicle-stimulating hormone (hFSH) has been introduced to increase sperm concentration, spermatogonial population, or both natural or assisted pregnancy rates (PRs) in oligozoospermic subjects with normal concentrations of gonadotropins. METHODS: Fifty infertile men affected by idiopathic azoospermia were enrolled in this study, after undergoing medical history, physical and clinical examination, baseline semen parameters and hormonal plasma concentrations...
August 7, 2017: Urologia
https://www.readbyqxmd.com/read/28796415/white-matter-tract-integrity-is-associated-with-antidepressant-response-to-lurasidone-in-bipolar-depression
#6
Martin J Lan, Harry Rubin-Falcone, Fatima Motiwala, Ying Chen, Jonathan W Stewart, David J Hellerstein, J John Mann, Patrick J McGrath
OBJECTIVES: Patients with bipolar disorder spend the most time in the depressed phase, and that phase is associated with the most morbidity and mortality. Treatment of bipolar depression lacks a test to determine who will respond to treatment. White matter disruptions have been found in bipolar disorder. Previous reports suggest that white matter disruptions may be associated with resistance to antidepressant medication, but this has never been investigated in a prospective study using a Food and Drug Administration (FDA)-approved medication...
August 10, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28791171/gold-nanoparticles-stabilized-with-sulphonated-imidazolium-salts-in-water-and-reverse-micelles
#7
Gustavo A Monti, Gabriela A Fernández, N Mariano Correa, R Darío Falcone, Fernando Moyano, Gustavo F Silbestri
Herein we describe the synthesis of gold nanoparticles (Au-NPs) in presence of sulphonated imidazolium salts [1,3-bis(2,6-diisopropyl-4-sodiumsulfonatophenyl)imidazolium (L1), 1-mesityl-3-(3-sulfonatopropyl)imidazolium (L2) and 1-(3-sulfonatopropyl)imidazolium (L3)] in water and in a confinement environment created by reverse micelles (RMs). The Au-NPs were characterized-with an excellent agreement between different techniques-by UV-vis spectroscopy, transmission electron microscopy (TEM), dynamic light scattering (DLS) and zeta potential...
July 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28790042/multicentre-randomised-controlled-trial-to-investigate-the-usefulness-of-continuous-pneumatic-regulation-of-tracheal-cuff-pressure-for-reducing-ventilator-associated-pneumonia-in-mechanically-ventilated-severe-trauma-patients-the-agate-study-protocol
#8
Nicolas Marjanovic, Denis Frasca, Karim Asehnoune, Catherine Paugam, Sigismond Lasocki, Carole Ichai, Jean-Yves Lefrant, Marc Leone, Claire Dahyot-Fizelier, Julien Pottecher, Dominique Falcon, Benoit Veber, Jean-Michel Constantin, Sabrina Seguin, Jérémy Guénézan, Olivier Mimoz
INTRODUCTION: Severe trauma represents the leading cause of mortality worldwide. While 80% of deaths occur within the first 24 hours after trauma, 20% occur later and are mainly due to healthcare-associated infections, including ventilator-associated pneumonia (VAP). Preventing underinflation of the tracheal cuff is recommended to reduce microaspiration, which plays a major role in the pathogenesis of VAP. Automatic devices facilitate the regulation of tracheal cuff pressure, and their implementation has the potential to reduce VAP...
August 7, 2017: BMJ Open
https://www.readbyqxmd.com/read/28782754/new-therapeutic-perspectives-in-type-1-diabetes-dietary-interventions-prevent-%C3%AE-cell-autoimmunity-by-modifying-the-gut-metabolic-environment
#9
Chiara Sorini, Ilaria Cosorich, Marika Falcone
No abstract text is available yet for this article.
August 7, 2017: Cellular & Molecular Immunology
https://www.readbyqxmd.com/read/28776480/italian-adaptation-of-the-functional-outcome-questionnaire-aphasia-initial-psychometric-evaluation
#10
Simona Spaccavento, Elisabetta Cafforio, Fara Cellamare, Antonia Colucci, Angela Di Palma, Rosanna Falcone, Angela Craca, Anna Loverre, Roberto Nardulli, Robert L Glueckauf
PURPOSE: To evaluate the psychometric properties of the Italian version of Functional Outcome Questionnaire - Aphasia. METHODS: Two hundred and five persons with stroke-related aphasia and right hemiparesis who received ongoing assistance from a family caregiver were assessed using the Functional Outcome Questionnaire - Aphasia, Aachener Aphasie Test, Token Test, Raven's Coloured Progressive Matrices, Functional Independence Measure (FIM), Functional Assessment Measure (FAM), and Quality of Life Questionnaire for Aphasics (QLQA)...
August 4, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28769676/a-new-species-of-rhodnius-from-brazil-hemiptera-reduviidae-triatominae
#11
João Aristeu da Rosa, Hernany Henrique Garcia Justino, Juliana Damieli Nascimento, Vagner José Mendonça, Claudia Solano Rocha, Danila Blanco de Carvalho, Rossana Falcone, Maria Tercília Vilela de Azeredo Oliveira, Kaio Cesar Chaboli Alevi, Jader de Oliveira
A colony was formed from eggs of a Rhodnius sp. female collected in Taquarussu, Mato Grosso do Sul, Brazil, and its specimens were used to describe R. taquarussuensissp. n. This species is similar to R. neglectus, but distinct characters were observed on the head, thorax, abdomen, female external genitalia and male genitalia. Chromosomal differences between the two species were also established.
2017: ZooKeys
https://www.readbyqxmd.com/read/28762146/the-influence-of-chemical-protection-on-the-content-of-heavy-metals-in-wheat-triticum-aestivum-l-growing-on-the-soil-enriched-with-granular-sludge
#12
E Wołejko, B Łozowicka, P Kaczyński, R Konecki, M Grobela
The presence of heavy metals in Triticum aestivum L. growing on the soil enriched with granular sludge after chemical protection was observed. The five variants of treatments using herbicide (Chwastox Turbo 340SL) and four fungicides (Topsin M 500SC, Amistar 250SC, Artea 330EC, and Falcon 460EC) were performed. On control and experimental plots, the concentration of Ni, Pb, Cr, and Cu in wheat leaves were in the range 0.32-0.99, 0.92-1.57, 0.89-6.31, and 7.08-12.59 mg/kg and in grains 0.03 to 0.11, 0.14-0...
August 2017: Environmental Monitoring and Assessment
https://www.readbyqxmd.com/read/28760958/two-interacting-ppr-proteins-are-major-arabidopsis-editing-factors-in-plastid-and-mitochondria
#13
Damien Guillaumot, Mauricio Lopez-Obando, Kevin Baudry, Alexandra Avon, Guillem Rigaill, Andéol Falcon de Longevialle, Benjamin Broche, Mizuki Takenaka, Richard Berthomé, Geert De Jaeger, Etienne Delannoy, Claire Lurin
RNA editing is converting hundreds of cytosines into uridines during organelle gene expression of land plants. The pentatricopeptide repeat (PPR) proteins are at the core of this posttranscriptional RNA modification. Even if a PPR protein defines the editing site, a DYW domain of the same or another PPR protein is believed to catalyze the deamination. To give insight into the organelle RNA editosome, we performed tandem affinity purification of the plastidial CHLOROPLAST BIOGENESIS 19 (CLB19) PPR editing factor...
July 31, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28758799/single-tracheal-inoculation-of-aspergillus-fumigatus-conidia-induced-aspergillosis-in-juvenile-falcons-falco-spp
#14
Dominik Fischer, Lieven Van Waeyenberghe, Klaus Failing, An Martel, Michael Lierz
Aspergillosis is a common and life-threatening respiratory disease in raptors with acute and chronic courses. Among raptors, gyr falcons (Falco rusticolus) and their hybrids are often declared to be highly susceptible with juvenile individuals being the most susceptible. However, species and age specific experimental studies are lacking and minimal infective doses for Aspergillus spp. conidia are unknown. Therefore, 8-week old, healthy gyr hybrid falcons (F. rusticolus X F. cherrug) (N=18) were experimentally infected with Aspergillus fumigatus using a single intratracheal inoculation with varying dosages of conidia (10(2) to 10(7) conidia)...
July 31, 2017: Avian Pathology: Journal of the W.V.P.A
https://www.readbyqxmd.com/read/28756692/the-safety-of-available-treatments-for-chronic-constipation
#15
Blanca Serrano-Falcon, Enrique Rey
INTRODUCTION: Chronic constipation is a frequent syndrome which, not only causes an appreciable deterioration in quality of life, but also entails a high economic cost due, among other things, to its treatment. This is because of the widespread use of laxatives, even by subjects who have not sought medical care, as well as little patient satisfaction with the treatment. Although this generally involves the use of drugs regarded as safe, there is no clear evidence about their short- and long-term effects, something that complicates appropriate prescription and follow-up by health professionals and hinders therapeutic compliance...
July 31, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28756385/impact-of-intrapatient-variability-ipv-in-tacrolimus-trough-levels-on-long-term-renal-transplant-function-multicentre-collaborative-retrospective-cohort-study-protocol
#16
Petra M Goldsmith, Matthew J Bottomley, Okidi Okechukwu, Victoria C Ross, Ryan Ghita, David Wandless, Stuart J Falconer, Stavros Papachristos, Philip Nash, Vitaliy Androshchuk, Marc Clancy
INTRODUCTION: High intrapatient variability (IPV) in tacrolimus trough levels has been shown to be associated with higher rates of renal transplant failure. There is no consensus on what level of IPV constitutes a risk of graft loss. The establishment of such a threshold could help to guide clinicians in identifying at-risk patients to receive targeted interventions to improve IPV and thus outcomes. METHODS AND ANALYSIS: A multicentre Transplant Audit Collaborative has been established to conduct a retrospective study examining tacrolimus IPV and renal transplant outcomes...
July 28, 2017: BMJ Open
https://www.readbyqxmd.com/read/28750330/modelling-the-transport-and-decay-processes-of-microbial-tracers-in-a-macro-tidal-estuary
#17
Amyrhul Abu-Bakar, Reza Ahmadian, Roger A Falconer
The Loughor Estuary is a macro-tidal coastal basin, located along the Bristol Channel, in the South West of the U.K. The maximum spring tidal range in the estuary is up to 7.5 m, near Burry Port Harbour. This estuarine region can experience severe coastal flooding during high spring tides, including extreme flooding of the intertidal saltmarshes at Llanrhidian, as well as the lower industrial and residential areas at Llanelli and Gowerton. The water quality of this estuarine basin needs to comply with the designated standards for safe recreational bathing and shellfish harvesting industries...
July 3, 2017: Water Research
https://www.readbyqxmd.com/read/28749525/perceived-barriers-to-implementing-screening-and-brief-intervention-for-alcohol-consumption-by-adolescents-in-hospital-emergency-department-in-spain
#18
María Falcón, Javier Navarro-Zaragoza, Rosa María García-Rodríguez, Daniel Nova-López, María Dulce González-Navarro, María Mercadal, Oscar García-Algar, Aurelio Luna Ruiz-Cabello
BACKGROUND: Screening for alcohol consumption in adolescents is widely justified in the health care field because of the particular vulnerability of this population, which starts drinking alcohol at a very early age and frequently consumes high levels of the same. Hospital emergency departments (ED) could be a good venue to manage early detection and carry out brief intervention (BI) programmes. OBJECTIVES: The aim of this study was to identify perceived barriers for medical staff of three hospitals in Spain to successfully implement a protocol for alcohol detection and BI for minors in the ED...
July 14, 2017: Adicciones
https://www.readbyqxmd.com/read/28747221/prevalence-of-heartworm-in-dogs-and-cats-of-madrid-spain
#19
José Alberto Montoya-Alonso, Rodrigo Morchón, Yaiza Falcón-Cordón, Soraya Falcón-Cordón, Fernando Simón, Elena Carretón
BACKGROUND: Dirofilaria immitis causes heartworm disease, a chronic and potentially fatal cardiopulmonary disease which mainly affects dogs and cats. It is present in most of Spain, due to favourable climatic factors. Madrid, located in the centre of the Iberian Peninsula, is the most highly populated city in the country. There is a lack of current data on canine heartworm and there are no published epidemiological data regarding feline heartworm in this region, therefore the aim of this study was to assess the prevalence and current distribution of canine and feline dirofilariosis in the province of Madrid...
July 26, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/28746926/histamine-iontophoresis-as-in-vivo-model-to-study-human-skin-inflammation-with-minimal-barrier-impairment-pilot-study-results-of-application-of-the-model-to-a-sensitive-skin-panel
#20
Denise Falcone, Natallia Uzunbajakava, Renée Richters, Peter C M van de Kerkhof, Piet E J van Erp
BACKGROUND/AIMS: Histamine iontophoresis is known to elicit itch and a wheal-and-flare reaction; however, its impact on the skin barrier and underlying compartments has not been thoroughly evaluated yet. The primary objective of this study was to characterize that using immunohistochemistry, biophysical measurements, and image analysis, and secondly, to explore whether skin reactions to this model differ in sensitive skin (SS). METHODS: Eighteen healthy subjects, n = 9 with SS and n = 9 with non-sensitive skin (NSS), were included based on a perception-based questionnaire...
July 27, 2017: Skin Pharmacology and Physiology
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