Vivienne Chuter, Nicolaas Schaper, Joseph Mills, Robert Hinchliffe, David Russell, Nobuyoshi Azuma, Christian-Alexander Behrendt, Edward J Boyko, Michael S Conte, Misty D Humphries, Lee Kirksey, Katharine C McGinigle, Sigrid Nikol, Joakim Nordanstig, Vincent Rowe, Jos C van den Berg, Maarit Venermo, Robert Fitridge
INTRODUCTION: Peripheral artery disease (PAD) is associated with an increased likelihood of delayed or non-healing of a diabetes-related foot ulcer, gangrene, and amputation. The selection of the most effective surgical technique for revascularisation of the lower limb in this population is challenging and there is a lack of conclusive evidence to support the choice of intervention. This systematic review aimed to determine, in people with diabetes and tissue loss, if direct revascularisation is superior to indirect revascularisation and if endovascular revascularisation is superior to open revascularisation for the outcomes of wound healing, minor or major amputation, and adverse events including mortality...
August 4, 2023: Diabetes/metabolism Research and Reviews