Elvira Anna Carbone, Mariarita Caroleo, Marianna Rania, Renato de Filippis, Francesca Condoleo, Federica Catalano, Matteo Aloi, Pasquale De Fazio, Franco Arturi, Marta Letizia Hribal, Teresa Vanessa Fiorentino, Cristina Segura-Garcia
Background and Objectives : The NUCB2 gene and its polymorphisms were identified as novel players in the regulation of food intake, potentially leading to obesity (OBE) and altered eating behaviors. Naltrexone/bupropion SR (NB) showed good efficacy and tolerability for treating OBE and altered eating behaviors associated with binge eating disorder (BED). This prospective study investigates the influence of NUCB2 gene polymorphism on NB treatment response in OBE and BED. Materials and Methods : Body mass index (BMI), eating (EDE-Q, BES, NEQ, GQ, Y-FAS 2...
February 17, 2024: Biomedicines