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Migraine with aura

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https://www.readbyqxmd.com/read/29682978/orgasmic-migraine-aura-report-of-two-cases
#1
Heather Angus-Leppan, Alice Caulfield
Background Paroxysmal neurological symptoms occurring with sex cause considerable anxiety and sometimes have a serious cause. Thunderclap headache is the most well-known and requires urgent investigation at first presentation for subarachnoid haemorrhage and other significant pathologies. After exclusion of underlying causes, many prove to be primary headache associated with sexual activity. Orgasmic migraine aura without headache is not currently recognised as a clinical entity. Case reports We report two patients with acephalgic orgasmic neurological symptoms fulfilling the criteria for migraine aura...
January 1, 2018: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29682977/subclinical-hypothyroidism-is-associated-with-migraine-a-case-control-study
#2
Elisa Rubino, Innocenzo Rainero, Francesca Garino, Costanza Vicentini, Flora Govone, Alessandro Vacca, Annalisa Gai, Salvatore Gentile, Guido Govone, Federico Ragazzoni, Lorenzo Pinessi, Maria Teresa Giordana, Paolo Limone
Background Recent studies suggested a potential association between both overt and subclinical hypothyroidism and migraine. Aims of this study were to estimate the comorbidity of migraine in patients with subclinical hypothyroidism and to evaluate associated clinical characteristics. Methods Using a case-control strategy, 151 consecutive subclinical hypothyroidism patients (mean age 48.36 ± 15.86 years) and 150 controls (mean age 50.86 ± 9.19 years) were recruited. In all subjects, migraine characteristics were collected through a direct interview...
January 1, 2018: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29681827/hemicrania-continua-associated-with-classic-scintillating-scotoma
#3
Eva Auffenberg, Friedemann Bender, Tobias Freilinger
Hemicrania continua (HC) is a rare primary headache disorder, characterized by persistent unilateral pain associated with cranial autonomic symptoms and prompt response to indomethacin. While migrainous features (including aura) have been recognized in cluster headache, there have been only single reports of HC with aura. Here, we report the case of a 53-year-old man with constant right-sided headache and superimposed exacerbations to severe pain lasting for several hours. Secondary etiologies were excluded, and a diagnosis of HC was established after prompt and complete response to treatment with indomethacin...
January 2018: Case Reports in Neurology
https://www.readbyqxmd.com/read/29671086/the-nrp1-migraine-risk-variant-shows-evidence-of-association-with-menstrual-migraine
#4
Charmaine E Pollock, Heidi G Sutherland, Bridget H Maher, Rodney A Lea, Larisa M Haupt, Alison Frith, E Anne MacGregor, Lyn R Griffiths
BACKGROUND: In 2016, a large meta-analysis brought the number of susceptibility loci for migraine to 38. While sub-type analysis for migraine without aura (MO) and migraine with aura (MA) found some loci showed specificity to MO, the study did not test the loci with respect to other subtypes of migraine. This study aimed to test the hypothesis that single nucleotide polymorphisms (SNPs) robustly associated with migraine are individually or collectively associated with menstrual migraine (MM)...
April 18, 2018: Journal of Headache and Pain
https://www.readbyqxmd.com/read/29670392/cerebral-blood-flow-velocity-in-migraine-and-chronic-tension-type-headache-patients
#5
S Karacay Ozkalayci, B Nazliel, H Z Batur Caglayan, C Irkec
Introduction: The present study seeks to use transcranial Doppler ultrasound to evaluate cerebral blood flow velocities in anterior and posterior circulation arteries, during an attack-free episode in migraine patients, with and without aura, as well as in chronic tension-type headache patients who were not receiving prophylactic medication. Methods: A total of 50 patients (35 female, 15 male) were evaluated during a headache-free episode: 30 migraine patients without aura (mean age: 32±8 years), 10 migraine patients with aura (mean age: 34±4 years), and 10 patients with chronic tension-type headache (mean age: 34±5 years)...
2018: Journal of Pain Research
https://www.readbyqxmd.com/read/29665696/nosographic-analysis-of-osmophobia-and-field-testing-of-diagnostic-criteria-including-osmophobia
#6
Mona Ameri Chalmer, Thomas Folkmann Hansen, Jes Olesen
Introduction Osmophobia has been suggested as an additional symptom of migraine without aura, and a high prevalence of osmophobia of up to 50% has been reported in the literature. We conducted a nosographic study of osmophobia in all migraineurs and tension-type headache patients and a field testing of suggested diagnostic criteria of osmophobia, presented in the appendix of the second edition of The International Classification of Headache Disorders and suggested by Silva-Néto et al. and Wang et al ., in migraine without aura and tension-type headache patients (n = 1934)...
January 1, 2018: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29661036/when-migraine-mimics-stroke-a-systematic-review
#7
Alberto Terrin, Giulia Toldo, Mario Ermani, Federico Mainardi, Ferdinando Maggioni
Background Migraine with aura may mimic an acute ischemic stroke, so that an improper administration of thrombolytic treatment can expose migrainous patients to severe adverse effects. Methods This systematic review quantifies the relevance of migraine with aura among stroke mimics, checking for thrombolysis' safety in these patients. We reviewed the literature after 1995, distinguishing from studies dealing with stroke mimics treated with systemic thrombolysis and those who were not treated with systemic thrombolysis...
January 1, 2018: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29658983/subclinical-vestibular-dysfunction-in-migraineurs-without-vertigo-a-clinical-study
#8
L Bernetti, C Pellegrino, I Corbelli, S Caproni, P Eusebi, M Faralli, G Ricci, P Calabresi, P Sarchielli
OBJECTIVES: This observational study aimed to investigate the presence of potential vestibular system subclinical dysfunction among migraineurs without a history of vertigo and dizziness compared with healthy controls. METHODS: Patients diagnosed with episodic migraine with and without aura were enrolled. All patients and healthy controls underwent vestibular examination using the following conventional tests: sitting position, Pagnini-McClure's, Dix-Hallpike's, head hanging, video head impulse, subjective visual vertical, Romberg, Fukuda, and caloric vestibular stimulation by Fitzgerald-Hallpike's tests...
April 16, 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29651899/caffeine-does-not-affect-susceptibility-to-cortical-spreading-depolarization-in-mice
#9
Nilufer Yalcin, Shih-Pin Chen, Esther S Yu, Tzu-Ting Liu, Jiin-Cherng Yen, Yahya B Atalay, Tao Qin, Furkan Celik, Arn Mjm van den Maagdenberg, Michael A Moskowitz, Cenk Ayata, Katharina Eikermann-Haerter
Several factors that modulate migraine, a common primary headache disorder, also affect susceptibility to cortical spreading depolarization (CSD). CSD is a wave of neuronal and glial depolarization and thought to underlie the migraine aura and possibly headache. Here, we tested whether caffeine, known to alleviate or trigger headache after acute exposure or chronic use/withdrawal, respectively, modulates CSD. We injected C57BL/6J mice with caffeine once (30, 60, or 120 mg/kg; i.p.) ( acute) or twice per day for one or two weeks ( chronic)...
January 1, 2018: Journal of Cerebral Blood Flow and Metabolism
https://www.readbyqxmd.com/read/29629600/visual-symptoms-and-childhood-migraine-qualitative-analysis-of-duration-location-spread-mobility-colour-and-pattern
#10
Mas Ahmed, Catriona Boyd, Radhika Vavilikolanu, Bushra Rafique
Aim To examine the characteristics of visual symptoms during attacks of migraine in children and adolescents. Method A qualitative analysis of prospectively collected data over 5 years, on characteristics of visual symptoms during migraine attacks. Diagnosis of migraine and aura was based on the International Classification of Headache Disorders 3rd edition beta version. We also provided the opportunity for patients to illustrate their visual aura symptoms to aid in diagnosis. Results Visual symptoms were reported by 387/1079 (36%) of migraineurs...
January 1, 2018: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/29619630/is-migraine-primarily-a-metaboloendocrine-disorder
#11
REVIEW
Innocenzo Rainero, Flora Govone, Annalisa Gai, Alessandro Vacca, Elisa Rubino
PURPOSE OF THE REVIEW: The goals of this review are to evaluate recent studies regarding comorbidity between migraine and different metabolic and endocrine disorders and to discuss the role of insulin resistance as a common pathogenetic mechanism of these diseases. RECENT FINDINGS: Recently, several studies showed that migraine is associated with insulin resistance, a condition in which a normal amount of insulin induces a suboptimal physiological response. All the clinical studies that used the oral glucose tolerance test to examine insulin sensitivity found that, after glucose load, there is in migraine patients a significant increase of both plasmatic insulin and glucose concentrations in comparison with controls...
April 4, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29597079/assessment-of-responsiveness-to-everyday-non-noxious-stimuli-in-pain-free-migraineurs-with-vs-without-aura
#12
Yelena Granovsky, Merav Shor, Alla Shifrin, Elliot Sprecher, David Yarnitsky, Tami Bar-Shalita
Migraineurs with aura (MWA) express higher inter-ictal response to non-noxious and noxious experimental sensory stimuli compared to migraineurs without aura (MWoA), but whether these differences also prevail in response to everyday non-noxious stimuli is not yet explored. This is a cross-sectional study testing fifty-three female migraineurs (30 MWA; 23 MWoA) that underwent wide battery of noxious psychophysical testing at pain-free phase, and completed a sensory responsiveness questionnaire and pain-related psychological questionnaires...
March 26, 2018: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/29593023/migraine-and-the-risk-of-cardiovascular-and-cerebrovascular-events-a-meta-analysis-of-16-cohort-studies-including-1-152-407-subjects
#13
Ahmed N Mahmoud, Amgad Mentias, Akram Y Elgendy, Abdul Qazi, Amr F Barakat, Marwan Saad, Ala Mohsen, Ahmed Abuzaid, Hend Mansoor, Mohammad K Mojadidi, Islam Y Elgendy
OBJECTIVES: To perform an updated meta-analysis to evaluate the long-term cardiovascular and cerebrovascular outcomes among migraineurs. SETTING: A meta-analysis of cohort studies performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. DATA SOURCES: The MEDLINE, Web of Science and Cochrane Central Register of Controlled Trials databases were searched for relevant articles. PARTICIPANTS: A total of 16 cohort studies (18 study records) with 394 942 migraineurs and 757 465 non-migraineurs were analysed...
March 27, 2018: BMJ Open
https://www.readbyqxmd.com/read/29592973/cortical-laminar-necrosis-in-a-case-of-migrainous-cerebral-infarction
#14
Vikram Khardenavis, Davala Krishna Karthik, Sharvari Kulkarni, Anirudda Deshpande
We report a 27-year-old woman, a known case of classical migraine headache, on oral contraceptive pills. She had a severe episode of migraine with visual aura attack, which continued late into the night. The next early morning, her headache persisted and she developed abrupt onset of dysarthria, right hemiparaesthesias. She attributed symptoms to her long-standing headache problem, and hence did not seek medical help for the next two weeks. The symptoms persisted despite her headache subsiding over the next 24 hours...
March 28, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29580567/association-of-depression-anxiety-and-post-traumatic-stress-disorder-with-migraine-data-from-kosovo
#15
Nexhmedin Shala, Shemsedin Dreshaj
INTRODUCTION: Migraine is ranked as the seventh leading cause of disability worldwide, and it is characterized by a manifestation of combined neurological, gastrointestinal, and autonomic symptoms linked with different provoking factors. AIM OF THE STUDY: This study investigates the association between migraine and PTSD, depression and anxiety in the Kosovo population during the post-war period. MATERIAL AND METHODS: 273 war survivors with headache were enrolled in the study and were divided into two groups: 153 individuals with confirmed migraine (the study group) and 120 individuals with non-migraine headaches (control group)...
March 15, 2018: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/29570476/patent-foramen-ovale-and-hypoxemia
#16
Mohammad K Mojadidi, Juan C Ruiz, Jason Chertoff, Muhammad O Zaman, Islam Y Elgendy, Ahmed N Mahmoud, Mohammad Al-Ani, Akram Y Elgendy, Nimesh K Patel, Ghanshyam Shantha, Jonathan M Tobis, Bernhard Meier
Patent foramen ovale (PFO), an embryonic remnant of the fetal circulation, is present in 20-25% of adults. While recent observational studies and clinical trials have established the link between PFO-mediated right-to-left shunting with cryptogenic stroke and migraine with aura, the role of a PFO in exacerbating hypoxemic medical conditions (i.e., sleep apnea, chronic obstructive pulmonary disease, pulmonary hypertension, platypnea-orthodeoxia, pulmonary arteriovenous malformation, high altitude pulmonary edema, and exercise desaturation) remains poorly evaluated...
March 22, 2018: Cardiology in Review
https://www.readbyqxmd.com/read/29557064/the-role-of-endothelin-in-the-pathophysiology-of-migraine-a-systematic-review
#17
REVIEW
Afrim Iljazi, Cenk Ayata, Messoud Ashina, Anders Hougaard
PURPOSE OF REVIEW: Vasoactive peptides play a key role in the attack-initiating cascade of migraine. Recent studies have highlighted a potentially important role for endothelin-1, a potent vasoconstrictor peptide, in migraine pathophysiology. Here, we review the current data on endothelin's involvement in migraine. RECENT FINDINGS: We identified 23 articles. Nine studies reported on endothelin-1 plasma concentrations in patients with migraine, eight studies investigated relevant genetic associations, five studies investigated endothelin-1 and spreading depression in animals, and one randomized controlled clinical trial tested the efficacy of an endothelin antagonist in the acute treatment of migraine in patients both with and without aura...
March 19, 2018: Current Pain and Headache Reports
https://www.readbyqxmd.com/read/29549622/targeted-acid-sensing-ion-channel-therapies-for-migraine
#18
REVIEW
Nazia Karsan, Eric B Gonzales, Gregory Dussor
Acid-sensing ion channels (ASICs) are a family of ion channels, consisting of four members; ASIC1 to 4. These channels are sensitive to changes in pH and are expressed throughout the central and peripheral nervous systems-including brain, spinal cord, and sensory ganglia. They have been implicated in a number of neurological conditions such as stroke and cerebral ischemia, traumatic brain injury, and epilepsy, and more recently in migraine. Their expression within areas of interest in the brain in migraine, such as the hypothalamus and PAG, their demonstrated involvement in preclinical models of meningeal afferent signaling, and their role in cortical spreading depression (the electrophysiological correlate of migraine aura), has enhanced research interest into these channels as potential therapeutic targets in migraine...
March 16, 2018: Neurotherapeutics: the Journal of the American Society for Experimental NeuroTherapeutics
https://www.readbyqxmd.com/read/29547158/clinical-characterization-of-neck-pain-in-migraine
#19
Sunil Pradhan, Surjyaprakash S Choudhury
Introduction: Several extracranial symptoms, including somatic pain syndormes, are known to occur in migraine. Though neck pain has been occasionally described with migraine, its precise association and nature is not yet clear. Objective: To study the incidence and characteristics of neck pain in migraine with particular emphasis on its occurrence as a trigger or a part of the symptom complex of migraine, as well as its association with different phases of the migraine attack...
March 2018: Neurology India
https://www.readbyqxmd.com/read/29545251/brain-diffusion-abnormalities-in-children-with-tension-type-and-migraine-type-headaches
#20
J D Santoro, N D Forkert, Q-Z Yang, S Pavitt, S J MacEachern, M E Moseley, K W Yeom
BACKGROUND AND PURPOSE: Tension-type and migraine-type headaches are the most common chronic paroxysmal disorders of childhood. The goal of this study was to compare regional cerebral volumes and diffusion in tension-type and migraine-type headaches against published controls. MATERIALS AND METHODS: Patients evaluated for tension-type or migraine-type headache without aura from May 2014 to July 2016 in a single center were retrospectively reviewed. Thirty-two patients with tension-type headache and 23 with migraine-type headache at an average of 4 months after diagnosis were enrolled...
March 15, 2018: AJNR. American Journal of Neuroradiology
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