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Migraine with aura

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https://www.readbyqxmd.com/read/29033640/identification-of-allodynic-migraine-patients-with-the-turkish-version-of-the-allodynia-symptom-checklist-reliability-and-consistency-study
#1
Osman Özgür Yalin, Derya Uludüz, Mehmet Ali Sungur, Hande Sart, Aynur Özge
INTRODUCTION: Cutaneous allodynia is regarded as an expression of central sensitization in migraine. Although the gold standard is quantitative sensory testing, several practical assessment questionnaires have been developed to assess allodynia in migraine. We aimed to establish the first valid Turkish allodynia assessment questionnaire based on a 12-item allodynia symptom checklist and to evaluate the associated factors. METHODS: The first part of the study included the translation and cultural adaptation of a Turkish version of the checklist...
September 2017: Noro Psikiyatri Arsivi
https://www.readbyqxmd.com/read/29026887/single-dose-intravenous-sodium-valproate-depakine-versus-dexamethasone-for-the-treatment-of-acute-migraine-headache-a-double-blind-randomized-clinical-trial
#2
Narges Karimi, Mahdiye Tavakoli, Jamshid Yazdani Charati, Mastoureh Shamsizade
OBJECTIVE: Migraine headache is a chronic and disabling condition in adults. Some studies have investigated the efficacy of sodium valproate in the treatment of acute migraine, but the effectiveness and tolerability of intravenous valproate as abortive therapy remains unclear. This study aimed to evaluate the effects of sodium valproate and dexamethasone in the treatment of acute migraine. METHODS: We conducted a double-blind randomized clinical trial including 90 patients aged 18 to 65 years with acute migraine headache but no aura...
September 2017: Clinical and Experimental Emergency Medicine
https://www.readbyqxmd.com/read/29025401/headache-symptoms-from-migraine-patients-with-and-without-aura-through-structure-validated-self-reports
#3
Jiawei Wang, Bingren Zhang, Chanchan Shen, Jinhua Zhang, Wei Wang
BACKGROUND: Headache symptoms self-reported by migraine patients are largely congruent with the clinician-used diagnostic criteria, but not always so. Patients' self-reports of headache symptoms might offer additional clues to characterize migraine with (MA) and without (MO) aura more precisely. METHODS: Firstly, we invited 324 participants with a life-long headache attack to answer an item-matrix measuring symptoms of primary headaches, then we performed both exploratory and confirmatory factor analyses to their answers and refined a headache symptom questionnaire...
October 12, 2017: BMC Neurology
https://www.readbyqxmd.com/read/29022143/comorbidity-of-gastrointestinal-disorders-migraine-and-tension-type-headache-a-cross-sectional-study-in-iran
#4
Fahimeh Martami, Zeinab Ghorbani, Maryam Abolhasani, Mansoureh Togha, Alipasha Meysamie, Alireza Sharifi, Soodeh Razeghi Jahromi
Migraine can be accompanied by some gastrointestinal (GI) disorders. In this study, we aimed to investigate the relationship between migraine and tension-type headache (TTH) and different lower and upper GI disorders as well as non-alcoholic fatty liver (NAFLD) and cholelithiasis. This cross-sectional study included 1574 overweight and obese participants who were referred to the Obesity Research Center of Sina Hospital, Tehran, Iran. The diagnosis of migraine and TTH was made by an expert neurologist based on the international classification of headache disorders-III β (ICHD III β)...
October 11, 2017: Neurological Sciences
https://www.readbyqxmd.com/read/29021356/volumetric-brain-changes-in-migraineurs-from-the-general-population
#5
Inge H Palm-Meinders, Enrico B Arkink, Hille Koppen, Souad Amlal, Gisela M Terwindt, Lenore J Launer, Mark A van Buchem, Michel D Ferrari, Mark C Kruit
OBJECTIVE: To assess volumetric brain changes in migraineurs from the general population compared with controls. METHODS: Structural brain changes in migraineurs from the general population-based MRI Cerebral Abnormalities in Migraine, an Epidemiologic Risk Analysis (CAMERA)-2 observational cohort study were assessed by state-of-the-art voxel-based morphometry. T1-weighted MRIs of 84 migraineurs (52 with aura, 32 without aura) and 35 headache-free controls were evaluated...
October 11, 2017: Neurology
https://www.readbyqxmd.com/read/29019040/migraine-like-visual-auras-among-traumatized-cambodians-with-ptsd-fear-of-ghost-attack-and-other-disasters
#6
Devon E Hinton, Ria Reis, Joop de Jong
This article profiles visual auras among traumatized Cambodian refugees attending a psychiatric clinic. Thirty-six percent (54/150) had experienced an aura in the previous 4 weeks, almost always phosphenes (48% [26/54]) or a scintillating scotoma (74% [40/54]). Aura and PTSD were highly associated: patients with visual aura in the last month had greater PTSD severity, 3.6 (SD = 1.8) versus 1.9 (SD = 1.6), t = 10.2 (df = 85), p < 0.001, and patients with PTSD had a higher rate of visual aura in the last month, 69% (22/32) versus 13% (7/55), odds ratio 15...
October 10, 2017: Culture, Medicine and Psychiatry
https://www.readbyqxmd.com/read/29018013/stroke-resulting-from-an-isolated-pulmonary-arteriovenous-malformation
#7
Jakob Saidman, Hossam Abdou, Sridhar Sampath Kumar
Isolated pulmonary arteriovenous malformations (PAVM) are rare, but can be responsible for paradoxical embolic events. It is important to recognise these situations early and intervene quickly to attain the best outcome. We describe the case of a 45-year-old woman with a long-standing history of migraines with aura who presented to the emergency department with left-sided weakness and slurred speech. Work-up was unclear and she was diagnosed with cryptogenic stroke. Follow-up transoesophageal echocardiogram was suggestive of an atrial septal defect, though no clear defect was evident...
October 10, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/29017164/aspirin-prophylaxis-for-migraine-with-aura-an-observational-case-series
#8
Wendy E Turk, Anouk Uiterwijk, Raphaël Pasmans, Vera Meys, Cenk Ayata, Peter J Koehler
No abstract text is available yet for this article.
October 10, 2017: European Neurology
https://www.readbyqxmd.com/read/29016952/migraine-does-not-affect-pain-intensity-perception-a-cross-sectional-study
#9
Antonio Russo, Alessandro Tessitore, Antonio Bruno, Mattia Siciliano, Laura Marcuccio, Marcello Silvestro, Gioacchino Tedeschi
Objective: To explore perceived pain intensity (PPI) in three drug-naïve patient groups characterized by homogeneous migraine phenotypes-migraine without aura without cutaneous allodynia (MwoA CA-), MwoA with ictal CA (MwoA CA+), and migraine with aura without cutaneous allodynia (MwA CA-)-compared with age- and sex-matched healthy controls (HCs). Methods: Using trigeminal heat stimulation (THS) at three different predefined intensities (41 °C, 51 °C, and 53 °C) performed by the contact heat-evoked potential stimulator (CHEPS), PPI was investigated in 34 patients with MwoA CA-, 30 patients with MwoA CA+, and 30 patients with MwA CA- compared with 30 age- and sex-matched HCs...
July 28, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/28994639/migraine-menopause-and-hormone-replacement-therapy
#10
E Anne MacGregor
Perimenopause marks a period of increased migraine prevalence in women and many women also report troublesome vasomotor symptoms. Migraine is affected by fluctuating estrogen levels with evidence to support estrogen 'withdrawal' as a trigger of menstrual attacks of migraine without aura, while high estrogen levels can trigger migraine aura. Maintaining a stable estrogen environment with estrogen replacement can benefit estrogen-withdrawal migraine particularly in women who would also benefit from relief of vasomotor symptoms...
January 1, 2017: Post Reproductive Health
https://www.readbyqxmd.com/read/28994605/explicit-diagnostic-criteria-for-transient-ischemic-attacks-to-differentiate-it-from-migraine-with-aura
#11
Elena R Lebedeva, Natalia M Gurary, Denis V Gilev, Anne Francke Christensen, Jes Olesen
Background The diagnosis of transient ischemic attacks is fraught with problems. The inter-observer agreement has repeatedly been shown to be low even in a neurological setting, and the specificity of the diagnosis is modest to low, reflected in a poor separation of transient ischemic attacks and mimics, particularly migraine with aura with its varied symptomatology. In other disease areas, explicit diagnostic criteria have improved sensitivity and specificity of diagnoses. We therefore present novel explicit diagnostic criteria for transient ischemic attacks tested for sensitivity and for specificity against migraine with aura...
January 1, 2017: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/28994319/a-review-of-clinical-safety-data-for-sumatriptan-nasal-powder-administered-by-a-breath-powered-exhalation-delivery-system-in-the-acute-treatment-of-migraine
#12
Stephen D Silberstein
Introduction AVP-825 (sumatriptan nasal powder) is an FDA-approved intranasal medication delivery system containing low-dose sumatriptan powder for acute treatment of migraine with or without aura in adults. AVP-825 utilizes unique nasal anatomy features to avoid limitations of other intranasal delivery methods. Areas covered Literature search terms: "AVP-825", "sumatriptan nasal powder", "intranasal sumatriptan", "sumatriptan safety", "sumatriptan acute migraine". Pharmacokinetic, Phase 2/3 studies, reviews (AVP-825) and metanalyses/reviews (sumatriptan) were evaluated...
October 10, 2017: Expert Opinion on Drug Safety
https://www.readbyqxmd.com/read/28990418/redox-mechanisms-in-migraine-novel-therapeutics-and-dietary-interventions
#13
Patrizia Ferroni, Piero Barbanti, David Della-Morte, Raffaele Palmirotta, Emilio Jirillo, Fiorella Guadagni
Significance Migraine represents the third most prevalent and the seventh most disabling human disorder. Approximately 30% of migraine patients experience transient, fully reversible, focal neurological symptoms (aura) preceding the attack. Recent advances Awareness of the hypothesis that migraine actually embodies a spectrum of illnesses - ranging from episodic to chronic forms - is progressively increasing and poses novel challenges for clarifying the underlying pathophysiological mechanisms of migraine as well as for the development of novel therapeutic interventions...
October 7, 2017: Antioxidants & Redox Signaling
https://www.readbyqxmd.com/read/28989805/migraine-and-stroke
#14
REVIEW
Yonghua Zhang, Aasheeta Parikh, Shuo Qian
Migraines are generally considered a relatively benign neurological condition. However, research has shown an association between migraines and stroke, and especially between migraine with aura and ischaemic stroke. Patients can also suffer from migrainous infarction, a subset of ischaemic stroke that often occurs in the posterior circulation of younger women. The exact pathogenesis of migrainous infarct is not known, but it is theorised that the duration and local neuronal energy level from cortical spreading depression may be a key factor...
September 2017: Stroke and Vascular Neurology
https://www.readbyqxmd.com/read/28985814/tear-osmolarity-and-subjective-dry-eye-symptoms-in-migraine-sufferers
#15
Melody Wong, Mary-Magdalene Dodd, Paul Masiowski, Vikas Sharma
OBJECTIVE: Previous studies have suggested an association between dry eye and migraine. In a busy ophthalmologist clinic, quick identification of dry eye in migraine sufferers may improve their quality of life. Tear osmolarity is an objective and reliable tool for diagnosing dry eye. It has not been investigated in any population with migraine. Using tear osmolarity and questionnaires, we aimed to explore the relationship between dry eye and clinical symptoms in patients with migraine...
October 2017: Canadian Journal of Ophthalmology. Journal Canadien D'ophtalmologie
https://www.readbyqxmd.com/read/28969391/migraine-and-risk-of-stroke-a-national-population-based-twin-study
#16
Maria Lantz, Johanna Sieurin, Arvid Sjölander, Elisabet Waldenlind, Christina Sjöstrand, Karin Wirdefeldt
Numerous studies have indicated an increased risk for stroke in patients with migraine, especially migraine with aura; however, many studies used self-reported migraine and only a few controlled for familial factors. We aimed to investigate migraine as a risk factor for stroke in a Swedish population-based twin cohort, and whether familial factors contribute to an increased risk. The study population included twins without prior cerebrovascular disease who answered a headache questionnaire during 1998 and 2002 for twins born 1935-58 and during 2005-06 for twins born between 1959 and 1985...
October 1, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28963615/brain-networking-analysis-in-migraine-with-and-without-aura
#17
Marina de Tommaso, Gabriele Trotta, Eleonora Vecchio, Katia Ricci, R Siugzdaite, Sebastiano Stramaglia
BACKGROUND: To apply effective connectivity by means of nonlinear Granger Causality (GC) and brain networking analysis to basal EEG and under visual stimulation by checkerboard gratings with 0.5 and 2.0 cpd as spatial frequency in migraine with aura (MA) and without aura (MO), and to compare these findings with Blood Oxygen Level Dependent (BOLD) signal changes. METHODS: Nineteen asymptomatic MA and MO patients and 11 age and sex matched controls (C) were recorded by 65 EEG channels...
September 29, 2017: Journal of Headache and Pain
https://www.readbyqxmd.com/read/28960327/migraine-and-yawning
#18
Bülent Güven, Hayat Güven, Selim Selçuk Çomoğlu
BACKGROUND: Yawning is considered to be a symptom that reflects dopaminergic activity, although its pathophysiological mechanism is not yet fully understood. Interestingly, repetitive yawning is seen in some patients during migraine attacks. The aim of this cross-sectional study is to investigate the frequency of yawning during migraine attacks and its association with different characteristics of migraine. METHODS: Patients with migraine with or without aura were evaluated using questionnaires and diaries to determine the characteristics of headache and accompanying symptoms...
September 27, 2017: Headache
https://www.readbyqxmd.com/read/28960288/a-case-of-migraine-with-aura-resolving-on-warfarin-but-not-on-apixaban
#19
Benjamin G Nilsson, Tammy J Bungard
Several case reports have associated anticoagulants such as heparin and vitamin K antagonists with reduced symptoms in migraine, but no data exist for direct acting oral factor Xa inhibitors. We report the case of a 55-year-old female who experienced complete remission of migraine with aura for 12 years while on warfarin, with return of symptoms within 3 weeks of switching to apixaban, and resolution of symptoms once again within days of warfarin resumption. Our case suggests that anticoagulation alone is not sufficient to improve migraine symptoms...
September 27, 2017: Headache
https://www.readbyqxmd.com/read/28958151/exploring-resting-state-eeg-complexity-before-migraine-attacks
#20
Zehong Cao, Kuan-Lin Lai, Chin-Teng Lin, Chun-Hsiang Chuang, Chien-Chen Chou, Shuu-Jiun Wang
Objective Entropy-based approaches to understanding the temporal dynamics of complexity have revealed novel insights into various brain activities. Herein, electroencephalogram complexity before migraine attacks was examined using an inherent fuzzy entropy approach, allowing the development of an electroencephalogram-based classification model to recognize the difference between interictal and preictal phases. Methods Forty patients with migraine without aura and 40 age-matched normal control subjects were recruited, and the resting-state electroencephalogram signals of their prefrontal and occipital areas were prospectively collected...
January 1, 2017: Cephalalgia: An International Journal of Headache
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