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Vocal fold dehydration

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https://www.readbyqxmd.com/read/27241580/quantitative-study-of-the-effects-of-dehydration-on-the-viscoelastic-parameters-in-the-vocal-fold-mucosa
#1
Shuai Yang, Yu Zhang, Randal D Mills, Jack J Jiang
OBJECTIVES: The goal of this study was to quantify the viscoelastic parameters of the vocal fold mucosa at varying dehydration levels. STUDY DESIGN AND METHODS: Healthy canine larynges were obtained postmortem, and the samples were separated from the subglottal wall. The samples were dehydrated in a vacuum dryer. According to the total dehydration time per sample, dehydration levels were divided into four degrees: 0%, 40%, 60%, and 80%. The stepper was set to stretch the sample to a level of 35% strain at the same rate (0...
May 27, 2016: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/26277075/spatiotemporal-quantification-of-vocal-fold-vibration-after-exposure-to-superficial-laryngeal-dehydration-a-preliminary-study
#2
Rita R Patel, Reuben Walker, Preeti M Sivasankar
OBJECTIVES: The aim of the study was to evaluate the effects of a superficial laryngeal dehydration challenge on vocal fold vibration in young healthy adults using high-speed video imaging. SUBJECTS AND METHODS: In this prospective study, the effects of a 60-minute superficial laryngeal dehydration challenge on spatial (speed quotient, amplitude quotient) and temporal measures (jitter percentage, vibratory onset time) of vocal fold vibration and phonation threshold pressure (PTP) were evaluated in 10 (male = 4, female = 6) vocally normal adults (21-29 years)...
July 2016: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/25944291/quantitative-study-for-the-surface-dehydration-of-vocal-folds-based-on-high-speed-imaging
#3
Lin Li, Yu Zhang, Allison L Maytag, Jack J Jiang
OBJECTIVES: From the perspective of the glottal area and mucosal wave, quantitatively estimate the differences of vocal fold on laryngeal activity during phonation at three different dehydration levels. STUDY DESIGN: Controlled three sets of tests. METHODS: A dehydration experiment for 10 excised canine larynges was conducted at 16 cm H2O. According to the dehydration cycle time (H), dehydration levels were divided into three degrees (0% H, 50% H, 75% H)...
July 2015: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/25781583/nebulized-isotonic-saline-improves-voice-production-in-sj%C3%A3-gren-s-syndrome
#4
Kristine Tanner, Shawn L Nissen, Ray M Merrill, Alison Miner, Ron W Channell, Karla L Miller, Mark Elstad, Katherine A Kendall, Nelson Roy
OBJECTIVE: This study examined the effects of a topical vocal fold hydration treatment on voice production over time. STUDY DESIGN: Prospective, longitudinal, within-subjects A (baseline), B (treatment), A (withdrawal/reversal), B (treatment) experimental design. METHODS: Eight individuals with primary Sjögren's syndrome (SS), an autoimmune disease causing laryngeal dryness, completed an 8-week A-B-A-B experiment. Participants performed twice-daily audio recordings of connected speech and sustained vowels and then rated vocal effort, mouth dryness, and throat dryness...
October 2015: Laryngoscope
https://www.readbyqxmd.com/read/24760548/computational-modeling-of-vibration-induced-systemic-hydration-of-vocal-folds-over-a-range-of-phonation-conditions
#5
Pinaki Bhattacharya, Thomas Siegmund
Predicting phonation conditions that are benign to voice health remains a biomechanically relevant problem. Our objective is to provide insight into vocal fold (VF) hydration based on continuum-based VF models that are able to compute VF stresses during phonation and a scheme for the extraction and generalization of such computational data based on the principle of linear superposition. Because VF tissue is poroelastic, spatial gradients of VF hydrostatic stresses computed for a given phonation condition determine VF interstitial fluid flow...
October 2014: International Journal for Numerical Methods in Biomedical Engineering
https://www.readbyqxmd.com/read/24686925/preliminary-results-on-the-influence-of-engineered-artificial-mucus-layer-on-phonation
#6
Michael Döllinger, Franziska Gröhn, David A Berry, Ulrich Eysholdt, Georg Luegmair
PURPOSE Previous studies have confirmed the influence of dehydration and an altered mucus (e.g., due to pathologies) on phonation. However, the underlying reasons for these influences are not fully understood. This study was a preliminary inquiry into the influences of mucus architecture and concentration on vocal fold oscillation. METHOD Two excised human larynges were investigated in an in vitro setup. The oscillations of the vocal folds at various airflow volume rates were recorded through the use of high-speed imaging...
April 1, 2014: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/24023753/rehydration-capacities-and-rates-for-various-porcine-tissues-after-dehydration
#7
Jacob P Meyer, Kieran E McAvoy, Jack Jiang
The biphasic effects of liquid on tissue biomechanics are well known in cartilage and vocal folds, yet not extensively in other tissue types. Past studies have shown that tissue dehydration significantly impacts biomechanical properties and that rehydration can restore these properties in certain tissue types. However, these studies failed to consider how temporal exposure to dehydrating or rehydrating agents may alter tissue rehydration capacity, as overexposure to dehydration may permanently prevent rehydration to the initial liquid volume...
2013: PloS One
https://www.readbyqxmd.com/read/23531170/a-computational-study-of-systemic-hydration-in-vocal-fold-collision
#8
Pinaki Bhattacharya, Thomas Siegmund
Mechanical stresses develop within vocal fold (VF) soft tissues due to phonation-associated vibration and collision. These stresses in turn affect the hydration of VF tissue and thus influence voice health. In this paper, high-fidelity numerical computations are described, taking into account fully 3D geometry, realistic tissue and air properties, and high-amplitude vibration and collision. A segregated solver approach is employed, using sophisticated commercial solvers for both the VF tissue and glottal airflow domains...
2014: Computer Methods in Biomechanics and Biomedical Engineering
https://www.readbyqxmd.com/read/22921296/influence-of-obligatory-mouth-breathing-during-realistic-activities-on-voice-measures
#9
COMPARATIVE STUDY
M Preeti Sivasankar, Elizabeth Erickson-Levendoski
OBJECTIVE: Low humidity environments and mouth breathing may contribute to superficial vocal fold dehydration. The purpose of this study was to investigate the effects of obligatory mouth breathing, during daily activities in low- and high-humidity environments, on voice measures. The activities included 15 minutes of obligatory mouth breathing alone, during loud reading and during exercise. The effects of mouth breathing and humidity were compared in subjects who either reported or did not report vocal worsening after heavy voice use...
November 2012: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/22804861/hoarseness-secondary-to-haemodialysis-case-report-and-literature-review
#10
M Santhirakumar, C Q Phua, Y Karagama
INTRODUCTION: Hoarseness is common and can have a major impact on patients' quality of life. We report a rare case of hoarseness secondary to haemodialysis. CASE REPORT: A 62-year-old man described developing transient hoarseness after haemodialysis sessions, which he underwent three times weekly. Fibre-optic nasendoscopy showed incomplete glottis closure due to bowing of the vocal folds. A computed tomography scan of the neck and thorax was unremarkable. Speech therapy was unhelpful...
August 2012: Journal of Laryngology and Otology
https://www.readbyqxmd.com/read/22483778/effects-of-dehydration-on-the-viscoelastic-properties-of-vocal-folds-in-large-deformations
#11
Amir K Miri, François Barthelat, Luc Mongeau
Dehydration may alter vocal fold viscoelastic properties, thereby hampering phonation. The effects of water loss induced by an osmotic pressure potential on vocal fold tissue viscoelastic properties were investigated. Porcine vocal folds were dehydrated by immersion in a hypertonic solution, and quasi-static and low-frequency dynamic traction tests were performed for elongations of up to 50%. Digital image correlation was used to determine local strains from surface deformations. The elastic modulus and the loss factor were then determined for normal and dehydrated tissues...
November 2012: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/21704493/investigating-the-effects-of-caffeine-on-phonation
#12
Elizabeth Erickson-Levendoski, Mahalakshmi Sivasankar
OBJECTIVE: A core component of vocal hygiene programs is the avoidance of agents that may dry the vocal folds. Clinicians commonly recommend that individuals reduce caffeine intake because of its presumed dehydrating effects on the voice. However, there is little evidence that ingestion of caffeine is detrimental to voice production. The first objective of this study was to evaluate whether caffeine adversely affects voice production. The second objective was to evaluate if caffeine exacerbates the adverse phonatory effects of vocal loading...
September 2011: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/21493398/effects-of-surface-dehydration-on-mucosal-wave-amplitude-and-frequency-in-excised-canine-larynges
#13
COMPARATIVE STUDY
Rachel E Witt, Lindsay N Taylor, Michael F Regner, Jack J Jiang
OBJECTIVE: Evaluate the effect of vocal fold surface dehydration on mucosal wave amplitude and frequency. STUDY DESIGN: Controlled test-retest. SETTING: Larynges were mounted on an excised larynx phonation system and attached to a pseudolung in a triple-walled sound-attenuated room that eliminated background noise and maintained a stabilized room temperature and humidity level. SUBJECTS AND METHODS: High-speed video was recorded for 8 excised canine larynges during exposure to dehumidified air at 20 cm H(2)O...
January 2011: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/20951551/ex-vivo-canine-vocal-fold-lamina-propria-rehydration-after-varying-dehydration-levels
#14
COMPARATIVE STUDY
Kevin P Hanson, Yu Zhang, Jack J Jiang
OBJECTIVES: To examine the recoverability of canine vocal fold (VF) lamina propria (LP) on rehydration from varying dehydration levels. STUDY DESIGN: Open, controlled experimental trial. METHODS: The VF LP was excised en bloc using a scalpel from 10 canine larynges, providing 20 tissue samples. The initial volume of each sample was measured. Ten samples were dehydrated to 30% by mass and the other 10 samples to 70%. Each sample was rehydrated in 0...
November 2011: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/20564654/parameters-quantifying-dehydration-in-canine-vocal-fold-lamina-propria
#15
Kevin P Hanson, Yu Zhang, Jack J Jiang
OBJECTIVES/HYPOTHESIS: The goal of this study was to measure the solid and liquid volume and mass of canine vocal fold lamina propria tissue at varying dehydration levels, and to calculate parameters to test the biphasic theory of vocal fold physiology and biomechanics. STUDY DESIGN: Open, controlled, experimental trial. METHODS: The vocal fold lamina propria was dissected from 15 canine larynges, yielding 30 tissue samples. The initial volumes and masses of the tissue samples were measured...
July 2010: Laryngoscope
https://www.readbyqxmd.com/read/20386449/the-role-of-hydration-in-vocal-fold-physiology
#16
REVIEW
Mahalakshmi Sivasankar, Ciara Leydon
PURPOSE OF REVIEW: Increased vocal fold hydration is a popular target in the prevention and management of voice disorders. Current intervention strategies focus on enhancing both systemic (internal) and superficial (surface) hydration. We review relevant bench and human research on the role of hydration in vocal fold physiology. RECENT FINDINGS: Bench and human studies provide converging evidence that systemic and superficial dehydration are detrimental to vocal fold physiology...
June 2010: Current Opinion in Otolaryngology & Head and Neck Surgery
https://www.readbyqxmd.com/read/20096227/hypertonic-challenge-to-porcine-vocal-folds-effects-on-epithelial-barrier-function
#17
Mahalakshmi Sivasankar, Elizabeth Erickson, Mark Rosenblatt, Ryan C Branski
OBJECTIVE: Dehydration challenges can increase the chemical composition of surface fluid overlying vocal fold epithelia (hypertonic surface fluid). The vocal fold epithelium is posited to act as a barrier, shielding the lamina propria from perturbations in the airway lumen. However, the effects of hypertonic surface fluid on the barrier functions of vocal fold epithelia have not been quantified. We, therefore, sought to investigate whether hypertonic surface fluid compromises epithelial barrier function...
January 2010: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/19672960/in-vivo-and-in-vitro-models-of-ionizing-radiation-to-the-vocal-folds
#18
Benjamin Saltman, Dennis H Kraus, Hazel Szeto, Bhupesh Parashar, Ronald Ghossein, Diane Felsen, Ryan C Branski
BACKGROUND: Radiation therapy (RT) to the head and neck often results in damage to the vocal folds (VF) and surrounding structures. Characterization and treatment of these sequelae is limited, likely due to the lack of experimental models. METHODS: Larynges from rats exposed to 2 fractionation schedules (40 Gy total) were analyzed histologically. In vitro, reactive oxygen species (ROS) synthesis, and transcription of select genes associated with ROS, inflammation, and fibrosis were examined in VF fibroblasts after single-dose radiation...
May 2010: Head & Neck
https://www.readbyqxmd.com/read/19522007/short-duration-accelerated-breathing-challenges-affect-phonation
#19
COMPARATIVE STUDY
Mahalakshmi Sivasankar, Elizabeth Erickson
OBJECTIVES/HYPOTHESIS: Inhaled air must be adequately humidified to prevent vocal fold drying, which is detrimental to phonation. The water content of inspired air is reduced by parameters, such as increased breathing rate and oral route. Accelerated oral breathing challenges induce airway dehydration and are posited to affect airway function. The primary objective of this study was to investigate whether accelerated oral breathing challenges are detrimental to phonation. The secondary objective of this study was to determine whether individuals at increased risk for developing voice problems (i...
August 2009: Laryngoscope
https://www.readbyqxmd.com/read/19354403/measurement-of-liquid-and-solid-component-parameters-in-canine-vocal-fold-lamina-propria
#20
Robert Phillips, Yu Zhang, Megan Keuler, Chao Tao, Jack J Jiang
This study aimed to measure solid and liquid component parameters for canine vocal fold lamina propria tissue, as is consistent with the solid and liquid fraction parameters in the context of the biphasic theory. A liquid-displacement apparatus was developed and utilized to estimate volumes of small samples of tissue. Accuracy was determined by calibrations with an object of known mass and density (copper). The experimental apparatus was then used to determine the volume of eight tissue samples, followed by an apparently complete dehydration of the samples, yielding the dry or solid tissue...
April 2009: Journal of the Acoustical Society of America
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