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https://www.readbyqxmd.com/read/29080870/-the-range-and-potential-contribution-of-irreversibly-adsorbed-proteins-on-the-surface-of-artificial-implants
#1
J V Ponomareva, L V Limareva, M N Milyakova
Protein adsorption is the first stage of the interaction between prosthetic materials with tissues of the body. They undergo conformational changes depending on the chemical composition and the nanotopography surface. Adsorbed proteins induce adhesion and alter the functional state of migrating cells. Plasma samples from patients were incubated with such matrices as titanium, polypropylene or polyester with fluoropolymer coating meshes. Bound peptides were analyzed by electrophoresis. Qualitative analysis of the peptides extracted from the gel was performed by chromatography-mass spectrometry...
October 2017: Biomedit︠s︡inskai︠a︡ Khimii︠a︡
https://www.readbyqxmd.com/read/29075100/biodegradable-rifampicin-releasing-coating-of-surgical-meshes-for-the-prevention-of-bacterial-infections
#2
Jochen Reinbold, Teresa Hierlemann, Lukas Urich, Ann-Kristin Uhde, Ingrid Müller, Tobias Weindl, Ulrich Vogel, Christian Schlensak, Hans Peter Wendel, Stefanie Krajewski
Polypropylene mesh implants are routinely used to repair abdominal wall defects or incisional hernia. However, complications associated with mesh implantation, such as mesh-related infections, can cause serious problems and may require complete surgical removal. Hence, the aim of the present study was the development of a safe and efficient coating to reduce postoperative mesh infections. Biodegradable poly(lactide-co-glycolide acid) microspheres loaded with rifampicin as an antibacterial agent were prepared through single emulsion evaporation method...
2017: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/29068557/in-vitro-study-on-the-deterioration-of-polypropylene-hernia-repair-meshes
#3
Dmitry Gil, James Rex, Vladimir Reukov, Alexey Vertegel
Despite the relative safety of the procedure, hernia repairs are often associated with chronic post-operative pain. Although this complication has been linked among others to mesh deterioration, details of the processes that lead this deterioration are still unknown. This work aims to bridge this gap by analyzing the chemical, physical and structural alterations in hernia repair meshes exposed to oxidative stress in vitro. Here, we developed a methodology to characterize effect of oxidation stress on structure and properties of polymeric hernia repair meshes...
October 25, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29064900/use-of-prophylactic-mesh-when-creating-a-colostomy-does-not-prevent-parastomal-hernia-a-randomized-controlled-trial-stomamesh
#4
Christoffer Odensten, Karin Strigård, Jörgen Rutegård, Michael Dahlberg, Ulrika Ståhle, Ulf Gunnarsson, Pia Näsvall
OBJECTIVE: The aim of this study was to determine whether parastomal hernia (PSH) rate can be reduced by using synthetic mesh in the sublay position when constructing permanent end colostomy. The secondary aim was to investigate possible side-effects of the mesh. BACKGROUND: Prevention of PSH is important as it often causes discomfort and leakage from stoma dressing. Different methods of prevention have been tried, including several mesh techniques. The incidence of PSH is high; up to 78%...
October 23, 2017: Annals of Surgery
https://www.readbyqxmd.com/read/29063325/comparative-study-of-sutureless-fixation-of-lightweight-surgical-meshes-for-hernia-repair-in-a-rat-model
#5
M V Anurov, G V Khachatrian, S M Titkova, P S Velangi, M D Polivoda, A P Oettinger
The aim of this study was to compare the efficacy of different methods of sutureless fixation of lightweight meshes made of different polymers for repair of experimental hernias. Two lateral hernia defects were modeled in male rats and covered with polyester and polypropylene prostheses. The meshes were fixed with Histacryl glue (group 1), or self-gripping meshes were used (group 2), or the meshes were implanted without fixation (group 3). On day 5 after surgery, mesh position and efficiency of fixation were evaluated...
October 2017: Bulletin of Experimental Biology and Medicine
https://www.readbyqxmd.com/read/29060222/integrating-coupled-magnetoelastic-sensors-onto-a-flexible-hernia-mesh-for-high-dynamic-range-strain-measurements
#6
Amy Liao, Hobart W Harris, Michel M Maharbiz
Despite better performance over primary repairs, tension-free ventral hernia repairs with mesh still suffer from a high recurrence rate. High stress gradients in the mesh are thought to contribute to hernia recurrence. We propose a postoperative monitoring system based on a coupled pair of magnetoelastic strain sensors to enable patients and physicians to non-invasively measure and track the strain distribution across the hernia mesh. Our design combines an encased resonator with a spring-loaded transducer to achieve high signal amplitude with a wide dynamic range...
July 2017: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/29030835/a-new-technique-for-tension-free-reconstruction-in-large-incisional-hernia
#7
Gabriele Munegato, Landino Fei, Michele Schiano di Visconte, Danilo Da Ros, Luana Moras, Gabriele Bellio
In the surgical management of large incisional hernias, the main target is the closure of the abdominal wall defect on the midline without a dangerous increase in the intraabdominal pressure. In this setting, new intraperitoneal prosthesis and components separation techniques were proposed to solve this problem. Both solutions present some critical issues. A new surgical approach with a free lateral double layer prosthesis totally in polypropylene both sides (FLaPp(®)) is proposed to overcome this problem...
December 2017: Updates in Surgery
https://www.readbyqxmd.com/read/29026977/mesh-versus-patch-repair-for-epigastric-and-umbilical-hernia-morpheus-trial-one-year-results-of-a-randomized-controlled-trial
#8
J E H Ponten, B J M Leenders, W K G Leclercq, T Lettinga, J Heemskerk, J L M Konsten, P S S Castelijns, S W Nienhuijs
DESIGN: This trial is a randomized controlled, patient-blinded, multicentre, superiority trial. METHODS: All patients ≥18 years with a single, symptomatic and primary umbilical or epigastric hernia (<2 fingers) qualified for participation in the study. Flat polypropylene mesh repair was compared to patch repair (PROCEED(®) Ventral Patch) (PVP). The objective of this trial was to identify a superior method for umbilical and epigastric hernia repair in terms of complication rates...
October 12, 2017: World Journal of Surgery
https://www.readbyqxmd.com/read/29024311/collagen-inducing-biologization-of-prosthetic-material-for-hernia-repair-polypropylene-meshes-coated-with-polyp-collagen
#9
Maximilian Ackermann, Xiaohong Wang, Shunfeng Wang, Meik Neufurth, Heinz C Schröder, Friedrich-Eckart Isemer, Werner E G Müller
Prostethic mesh material such as nonabsorbable polypropylene used in open and laparoscopic hernia repair are characterized by controllable mechanical properties but may elicit undesirable physiological reactions due to the nonphysiological inert polymer material. We succeeded in developing a biocompatible coating for these meshes, based on a physiological inorganic polymer, polyphosphate (polyP) that is morphogenetically active and used as a metabolic energy source, and a collagen matrix. The polyP/collagen hydrogel material was prepared by a freeze-extraction method, with amorphous Ca-polyP microparticles...
October 10, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/29019554/tensiometric-analysis-of-meshes-used-in-abdominal-ventral-wall-defects-in-rats
#10
Carlos Alberto Lima Utrabo, Nicolau Gregori Czeczko, Cesar Roberto Busato, Mário Rodrigues Montemór-Netto, Leandro Lipinski, Osvaldo Malafaia
BACKGROUND: Among the various strategies to avoid exaggerated foreign body reaction in the treatment of hernias is the limitation of the amount of polypropylene or the use of absorbable material. AIM: To evaluate the healing of defects in the abdominal wall of rats, comparing microporous polypropylene, macroporous polypropylene and polypropylene/polyglecaprone at the 30º, 60º and 120º postoperative day. METHODS: Wistar rats were submitted to defect production in the ventral abdominal wall, with integrity of the parietal peritoneum...
July 2017: Arquivos Brasileiros de Cirurgia Digestiva: ABCD, Brazilian Archives of Digestive Surgery
https://www.readbyqxmd.com/read/28982622/retroperitoneal-compartment-syndrome-in-renal-transplantation-how-to-salvage-the-graft
#11
Karen Pineda-Solís, Wen Yan Xie, Vivian McAlister, Alp Sener, Patrick P Luke
OBJECTIVE: Early allograft dysfunction may be caused by several technical factors including vascular complications such as thrombosis, kinking, or extrinsic compression. Renal allograft compartment syndrome (RACS) is an unrecognized cause of early allograft dysfunction. This complication is characterized by increased pressure of the iliac fossa that reduces the blood supply to the graft with a potentially devastating consequence. The main objective when recognizing this condition is to create a tension-free muscle closure...
September 2017: Urology
https://www.readbyqxmd.com/read/28980021/comparison-of-strength-of-sacrocolpopexy-mesh-attachment-using-barbed-and-nonbarbed-sutures
#12
Marjorie L Pilkinton, Gregory C Levine, Laura Bennett, Harvey A Winkler, Dara F Shalom, Peter S Finamore
INTRODUCTION AND HYPOTHESIS: We aimed to assess the pull-out strength of barbed and nonbarbed sutures used in sacrocolpopexy mesh fixation. We hypothesized there are no differences in the force needed to dislodge mesh from tissue using barbed and nonbarbed sutures of similar size. METHODS: Using the rectus fascia of three unembalmed cadavers, a 6 × 3 cm strip of polypropylene mesh was anchored to the fascia with sutures. The barbed sutures investigated were 2-0 V-Loc 180 (nine trials) and 3-0 bidirectional Quill™ SRS PDO (five trials)...
October 4, 2017: International Urogynecology Journal
https://www.readbyqxmd.com/read/28979859/hernia-mesh-prevent-dislocation-after-wide-excision-and-reconstruction-of-giant-cell-tumor-distal-radius
#13
I Gede E Wiratnaya, I Gusti Bagus Arie M Budiartha, I Gusti Ngurah Y Setiawan, Dwijo A Sindhughosa, I Ketut S Kawiyana, Putu Astawa
Giant cell tumor (GCT) remains as major health problem. GCT which located at the lower end of the radius tends to be more aggressive. Wide excision and reconstruction of the wrist in stage 3 of distal radius GCT lesion is an optimal modality to prevent tumor recurrence. However, dislocation often occurs as its complication. We are reporting patient with GCT of distal radius treated with wide excision and reconstruction using nonvascularized fibular graft and the addition of hernia mesh. Circumferential non-absorbable polypropylene hernia mesh was applied, covered radioulnar joint and volar aspect of radius, and served as additional support to prevent dislocation...
September 18, 2017: World Journal of Orthopedics
https://www.readbyqxmd.com/read/28969193/comparing-early-outcomes-using-non-absorbable-polypropylene-mesh-and-partially-absorbable-composite-mesh-through-laparoscopic-transabdominal-preperitoneal-repair-of-inguinal-hernia
#14
Tarun Kalra, Rajesh Kumar Soni, Ajit Sinha
INTRODUCTION: Laparoscopic hernia repair is in vogue in the present era. Both the operating surgeon and the patient are concerned about the postoperative inguinodynia which has now replaced recurrence as the predominant factor affecting quality of life. AIM: Our study aimed to compare early postoperative outcomes with the standard non absorbablepolypropylene and the newer partially absorbable composite meshes. MATERIALS AND METHODS: A total of 60 patients with unilateral uncomplicated inguinal hernia were included in the study and randomly divided into two groups, one each for one kind of mesh...
August 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28959063/quality-of-life-sexuality-anatomical-results-and-side-effects-of-implantation-of-an-alloplastic-mesh-for-cystocele-correction-at-follow-up-after-36-months
#15
Christian Fünfgeld, Margit Stehle, Brigit Henne, Jan Kaufhold, Dirk Watermann, Markus Grebe, Mathias Mengel
INTRODUCTION: Pelvic organ prolapse can significantly reduce quality of life of affected women, with many cases requiring corrective surgery. The rate of recurrence is relatively high after conventional prolapse surgery. In recent years, alloplastic meshes have increasingly been implanted to stabilize the pelvic floor, which has led to considerable improvement of anatomical results. But the potential for mesh-induced risks has led to a controversial discussion on the use of surgical meshes in urogynecology...
September 2017: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28956206/in-vitro-study-of-the-mechanical-performance-of-hernia-mesh-under-cyclic-loading
#16
Rita Rynkevic, Pedro Martins, Francisco Pereira, Nilza Ramião, António A Fernandes
The use of prostheses for hernia surgery, made from synthetic polymers may lead to development of postoperative complications. The reason for this can be the mismatch of the mechanical properties of meshes and the loads acting on them. The aim of this work was to investigate the behavior of 3 different hernia meshes under in vitro simulated physiological conditions followed by cyclic loadings. Meshes, Ultrapro (poliglecaprone and polypropylene), Dynamesh (polyvinylidenefluoride) and Surgipro (polypropylene) were selected...
September 27, 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28925270/-reconstruction-of-the-posterior-and-central-compartment-with-the-prolift-posterior-cohort-study-with-a-5-year-follow-up
#17
K Brányik, L Krofta, P Kraus, M Krčmář, O Gojiš, I Urbánková, J Feyereisl
OBJECTIVE: To analyse the results of the long-term prospective follow-up study of vaginal prolapse reconstructed using a Prolift Posterior. STUDY DESIGN: Prospective, cohort study. SETTING: Institute for the Care of Mother and Child, Prague. METHODS: Over a 5-year period (I/2006 - XII/2011) we prospectively followed a cohort of patients with posterior vaginal wall defect who underwent surgical reconstruction using a monofilament polypropylene implant Prolift Posterior (Gynecare, Ethicon, Inc...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/28922558/biomechanical-properties-and-healing-effects-of-chitin-patch-in-a-rat-full-thickness-abdominal-wall-defect-model
#18
Jing Qiao, Zhiwen Jiang, Xuyue Liang, Yan Yang, Wanshun Liu, Baoqin Han
Hernia repair is usually accompanied with the implantation of a synthetic mesh, which frequently results in a foreign body response and serious complications. In the present study, a novel biodegradable chitin-based hernia patch was prepared and characterized. Biomechanical properties and biodegradability of the chitin patch were quantified in vitro and in vivo. In repair of the rat abdominal wall full-thickness defect model, the chitin patch induced more abundant new blood vessels with milder tissue inflammation and fibrosis compared with polypropylene mesh...
September 18, 2017: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
https://www.readbyqxmd.com/read/28912989/vaginal-urinary-calculi-formation-secondary-to-vaginal-mesh-exposure-with-urinary-incontinence
#19
Kara M Griffiths, Geoffrey D Towers, Jerome L Yaklic
BACKGROUND: Vaginal stones may form in the setting of mesh exposure with urinary incontinence. This report serves to help understand the presentation, evaluation, and management of vaginal urinary stones. CASE: A 68-year-old female presented with a vaginal calculus. She had a history of anterior and posterior polypropylene mesh placement for prolapse 7 years earlier and urinary incontinence. The stone was identified on a portion of exposed mesh and removed in office...
2017: Case Reports in Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28901533/characteristics-of-different-mesh-types-for-abdominal-wall-repair-in-an-experimental-model-of-peritonitis
#20
R Kaufmann, A P Jairam, I M Mulder, Z Wu, J Verhelst, S Vennix, L J X Giesen, M C Clahsen-van Groningen, J Jeekel, J F Lange
BACKGROUND: The use of synthetic mesh to repair a potentially contaminated incisional hernia may lead to higher failure rates. A biological mesh might be considered, but little is known about long-term results. Both biological and synthetic meshes were investigated in an experimental model of peritonitis to assess their characteristics in vivo. METHODS: Male Wistar rats were randomized into five groups and peritonitis was induced. A mesh was implanted after 24 h...
September 13, 2017: British Journal of Surgery
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