keyword
https://read.qxmd.com/read/38412596/thoracolumbar-junction-translation-injury-in-a-patient-with-ankylosing-spondylitis-a-case-report
#21
Daniel Rovelt Mwanga, Mathias Switbert Ncheye, Godlisten Samwel Kawiche, Honnest Herman Massawe, Peter Magembe Mrimba, Faiton Ndesanjo Mandari
INTRODUCTION: The thoracic spine is stable because of kyphotic alignment, rib cage, and costovertebral joints. Any compression or kyphosis in the thoracic spine always causes spinal cord injury. CLINICAL CASE: A 47-year-old male with complaints of back pain 1 day prior to admission, after he sustained a motorbike crush and landed on his back. The pain, radiates to both limbs, associated with severe spasms, numbness, and weakness in his lower extremities, however no incontinence...
February 24, 2024: International Journal of Surgery Case Reports
https://read.qxmd.com/read/38407343/formal-radiologist-interpretations-of-intraoperative-spine-radiographs-have-low-clinical-value
#22
JOURNAL ARTICLE
Ryan T Lin, Jonathan F Dalton, Christopher J Como, Audrey Y Chang, Melissa Yunting Tang, Anthony A Oyekan, Shaan Sadhwani, Richard A Wawrose, Joon Y Lee, Jeremy D Shaw
STUDY DESIGN: Retrospective cohort. OBJECTIVE: To evaluate the clinical relevance, usefulness, and financial implications of intraoperative radiograph interpretation by radiologists in spine surgery. SUMMARY OF BACKGROUND DATA: Due to rising healthcare costs, spine surgery is under scrutiny to maximize value-based care. Formal radiographic analysis remains a potential source of unnecessary healthcare costs, especially for intra-operative radiographs...
February 26, 2024: Spine
https://read.qxmd.com/read/38393926/dry-needling-combined-with-exercise-therapy-effects-on-wrist-flexors-spasticity-in-post-stroke-patients-a-randomized-controlled-trial
#23
JOURNAL ARTICLE
Seyedeh Saeideh Babazadeh-Zavieh, Noureddin Nakhostin Ansari, Nastaran Ghotbi, Soofia Naghdi, Seyed Mohammad Jafar Haeri
BACKGROUND: The positive contribution of dry needling (DN) in conjunction with exercise therapy for patients with stroke and spasticity remains uncertain. OBJECTIVE: To examine the effects of DN combined with exercise therapy on wrist flexor spasticity and motor function in patients with stroke. METHODS: Twenty-four participants with stroke were randomly assigned to either the DN and exercise therapy group or the DN alone group. Assessments were conducted at baseline, after the 4th treatment session, and 3 weeks post-treatment...
February 23, 2024: NeuroRehabilitation
https://read.qxmd.com/read/38391752/mesencephalic-locomotor-region-and-presynaptic-inhibition-during-anticipatory-postural-adjustments-in-people-with-parkinson-s-disease
#24
JOURNAL ARTICLE
Carla Silva-Batista, Jumes Lira, Daniel Boari Coelho, Andrea Cristina de Lima-Pardini, Mariana Penteado Nucci, Eugenia Casella Tavares Mattos, Fernando Henrique Magalhaes, Egberto Reis Barbosa, Luis Augusto Teixeira, Edson Amaro Junior, Carlos Ugrinowitsch, Fay B Horak
Individuals with Parkinson's disease (PD) and freezing of gait (FOG) have a loss of presynaptic inhibition (PSI) during anticipatory postural adjustments (APAs) for step initiation. The mesencephalic locomotor region (MLR) has connections to the reticulospinal tract that mediates inhibitory interneurons responsible for modulating PSI and APAs. Here, we hypothesized that MLR activity during step initiation would explain the loss of PSI during APAs for step initiation in FOG (freezers). Freezers (n = 34) were assessed in the ON-medication state...
February 15, 2024: Brain Sciences
https://read.qxmd.com/read/38391694/sensory-stimulation-of-the-triceps-surae-muscle-complex-modulates-spinal-reflex-responses-a-comparison-between-tapotement-massage-and-repetitive-peripheral-magnetic-stimulation-rpms
#25
JOURNAL ARTICLE
Volker R Zschorlich, Fengxue Qi, Jörg Schorer, Dirk Büsch
BACKGROUND: The reduction of muscular hypertonia is important in the treatment of various diseases or rehabilitation. This study aims to test the efficacy of a 5 Hz mechanical muscle stimulation (tapotement massage) in comparison to a 5 Hz repetitive peripheral magnetic stimulation (rPMS) on the neuromuscular reflex response. METHODS: In a randomized control trial, 15 healthy volunteers were administered with either 5 Hz rPMS, tapotement massage, or rPMS sham stimulation...
January 24, 2024: Brain Sciences
https://read.qxmd.com/read/38389900/alcohol-use-and-the-pain-system
#26
REVIEW
Michael Vigorito, Sulie L Chang
The World Health Organization's epidemiological data from 2016 revealed that while 57% of the global population aged 15 years or older had abstained from drinking alcohol in the previous year, more than half of the population in the Americas, Europe, and Western Pacific consumed alcohol. The spectrum of alcohol use behavior is broad: low-risk use (sensible and in moderation), at-risk use (e.g., binge drinking), harmful use (misuse) and dependence (alcoholism; addiction; alcohol use disorder). The at-risk use and misuse of alcohol is associated with the transition to dependence, as well as many damaging health outcomes and preventable causes of premature death...
2024: Adv Drug Alcohol Res
https://read.qxmd.com/read/38389612/osteopathic-manipulative-treatment-in-dysmenorrhea-a-systematic-review
#27
REVIEW
Paige E Bonner, Heather A Paul, Rohit S Mehra
The majority of women experience dysmenorrhea during their lifetime. The current standard-of-care treatment consists of nonsteroidal anti-inflammatory drugs, oral contraceptive pills, or intrauterine devices. Osteopathic manipulative treatment (OMT) is a beneficial tool for improving non-musculoskeletal (non-MSK) conditions such as migraines, gastroesophageal reflux disease (GERD), and anxiety. OMT should be utilized to improve other non-MSK conditions, such as dysmenorrhea. The current review aims to evaluate the effects of OMT in women with dysmenorrhea...
January 2024: Curēus
https://read.qxmd.com/read/38376034/natural-polyphenolic-coffee-extract-administration-relieves-chronic-nociplastic-pain-in-a-reserpine-induced-fibromyalgia-like-female-mouse-model
#28
JOURNAL ARTICLE
Rubén Toledano-Martos, Anna Bagó-Mas, Meritxell Deulofeu, Judit Homs, Núria Fiol, Enrique Verdú, Pere Boadas-Vaello
INTRODUCTION: Nociplastic pain involves reflexive and nonreflexive pain responses and it is a core symptom of fibromyalgia (FM). The increasing prevalence of this health condition and the low rates of patients' quality of life, combined with the lack of suitable pharmacologic treatments, evidence the demand to research new alternatives. Polyphenols may be potential therapeutic candidates as they have been reported to exert pathological pain modulation in preclinical models. In that context, this work was aimed to study the antinociceptive effects of a polyphenolic extract obtained from decaffeinated ground roasted coffee, in the RIM6 FM-like mouse model...
January 2024: Brain and Behavior
https://read.qxmd.com/read/38373295/brainstem-anesthesia-during-awake-craniotomy-illustrative-case
#29
JOURNAL ARTICLE
Yun Chen, Mei Sun, Hongmin Bai, Ruixin Yang, Huan He
BACKGROUND: Awake craniotomy (AC) is performed to remove the lesions near or in eloquent areas, during which the patients are alert and without any airway instrument. Apnea is a severe complication in AC. Here, the authors describe a case of sudden apnea induced by unexpected local anesthesia of the brainstem during AC. OBSERVATIONS: A 42-year-old male underwent AC for a large, recurrent, bilateral frontal lobe mass and experienced transient apnea and loss of brainstem reflexes during the surgery...
February 19, 2024: J Neurosurg Case Lessons
https://read.qxmd.com/read/38373015/the-effect-of-vestibular-and-somatosensory-rehabilitation-in-addition-to-early-rehabilitation-on-balance-after-stroke-a-randomized-controlled-trial
#30
JOURNAL ARTICLE
Elisa Calisgan, Burcu Talu
BACKGROUND: The goal of post-stroke early rehabilitation is to regain ambulation, standing and balance. OBJECTIVE: The purpose of this study was to investigate the effects of vestibular and somatosensory rehabilitation in addition to early rehabilitation on balance in patients with early subacute stroke. DESIGN AND SETTING: A randomized controlled trial was conducted at a university hospital. METHODS: The study was included 52 hemiplegic hospitalized early suacute stroke patients...
February 19, 2024: Topics in Stroke Rehabilitation
https://read.qxmd.com/read/38368076/penile-vibratory-stimulation-in-men-with-spinal-cord-injury-an-educational-video-demonstration
#31
JOURNAL ARTICLE
Emad Ibrahim
OBJECTIVES: To demonstrate the different techniques used to perform successful penile vibratory stimulation (PVS) to induce ejaculation in men with spinal cord injuries (SCIs). DESIGN: A video demonstration of the PVS procedure performed in men with SCIs using the FertiCare 2.0 medical vibrator. SETTING: Major University Medical Center. PATIENTS: Men with SCIs. INTERVENTION(S): Spinal cord injury is the leading cause of anejaculation in young men...
March 2024: Fertility and Sterility
https://read.qxmd.com/read/38367237/modulation-of-central-synapse-remodeling-after-remote-peripheral-injuries-by-the-ccl2-ccr2-axis-and-microglia
#32
JOURNAL ARTICLE
Travis M Rotterman, Zoë Haley-Johnson, Tana S Pottorf, Tavishi Chopra, Ethan Chang, Shannon Zhang, William M McCallum, Sarah Fisher, Haley Franklin, Myriam Alvarez, Timothy C Cope, Francisco J Alvarez
Microglia-mediated synaptic plasticity after CNS injury varies depending on injury severity, but the mechanisms that adjust synaptic plasticity according to injury differences are largely unknown. This study investigates differential actions of microglia on essential spinal motor synaptic circuits following different kinds of nerve injuries. Following nerve transection, microglia and C-C chemokine receptor type 2 signaling permanently remove Ia axons and synapses from the ventral horn, degrading proprioceptive feedback during motor actions and abolishing stretch reflexes...
February 15, 2024: Cell Reports
https://read.qxmd.com/read/38366214/soleus-h-reflex-amplitude-modulation-during-walking-remains-physiological-during-transspinal-stimulation-in-humans
#33
JOURNAL ARTICLE
Abdullah M Sayed Ahmad, Meghan Raphael, Jessy Feng Han, Yoseph Ahmed, Mohamed Moustafa, Shammah K Solomon, Andreas Skiadopoulos, Maria Knikou
The soleus H-reflex modulation pattern was investigated during stepping following transspinal stimulation over the thoracolumbar region at 15, 30, and 50 Hz with 10 kHz carry-over frequency above and below the paresthesia threshold. The soleus H-reflex was elicited by posterior tibial nerve stimulation with a single 1 ms pulse at an intensity that the M-wave amplitudes ranged from 0 to 15% of the maximal M-wave evoked 80 ms after the test stimulus, and the soleus H-reflex was half the size of the maximal H-reflex evoked on the ascending portion of the recruitment curve...
February 16, 2024: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://read.qxmd.com/read/38356241/a-single-sequence-of-intermittent-hypoxia-does-not-alter-stretch-reflex-excitability-in-able-bodied-individuals
#34
JOURNAL ARTICLE
Andrew Q Tan, Christopher Tuthill, Anthony N Corsten, Stella Barth, Randy D Trumbower
Spasticity attributable to exaggerated stretch reflex pathways, particularly affecting the ankle plantar flexors, often impairs overground walking in persons with incomplete spinal cord injury. Compelling evidence from rodent models underscores how exposure to acute intermittent hypoxia (AIH) can provide a unique medium to induce spinal plasticity in key inhibitory pathways mediating stretch reflex excitability and potentially affect spasticity. In this study, we quantify the effects of a single exposure to AIH on the stretch reflex in able-bodied individuals...
February 14, 2024: Experimental Physiology
https://read.qxmd.com/read/38353259/transforming-research-systems-for-meaningful-engagement-a-reflexive-thematic-analysis-of-spinal-cord-injury-researchers-barriers-and-facilitators-to-using-the-integrated-knowledge-translation-guiding-principles
#35
JOURNAL ARTICLE
Heather L Gainforth, Alanna Shwed, Emily E Giroux, Femke Hoekstra, Rhyann C McKay, Lee Schaefer, Kathryn M Sibley, Anita Kaiser, Lowell McPhail, Christopher B McBride, Barry Munro, Christopher R West
PURPOSE: To develop an in-depth understanding of spinal cord injury (SCI) researchers' barriers and facilitators to deciding to use 1) a partnered approach to research and, 2) systematically developed principles for guiding Integrated Knowledge Translation (IKT) in spinal cord injury research (IKT Guiding Principles). METHODS: Qualitative interview study with North American SCI researchers who were interested in using a partnered research approach. The research was conducted using an IKT approach, and interview data were analyzed using reflexive thematic analysis...
February 14, 2024: Disability and Rehabilitation
https://read.qxmd.com/read/38349192/spinal-lymphoma-in-a-goat
#36
Jannis Nankemann, Merrilee Holland, Samantha Glamann, Robert Cole, Jenna Stockler, Rachel Moon
A 3-year-old Pygmy Wether was presented for chronic hindlimb paralysis. A neurological exam revealed nonambulatory paraplegia with absent deep pain nociception, lack of hindlimb withdrawal reflexes, and paraspinal pain on palpation with T3 to L3 neurolocalization. MRI of the lumbar spine revealed an extensive, dorsal to dorsolateral, severely compressive, heterogeneously contrast-enhancing extradural lesion of the lumbar spine with intervertebral foraminal extension into the surrounding paraspinal musculature...
February 13, 2024: Veterinary Radiology & Ultrasound
https://read.qxmd.com/read/38337396/neuromuscular-electrical-stimulation-does-not-influence-spinal-excitability-in-multiple-sclerosis-patients
#37
JOURNAL ARTICLE
Martina Scalia, Riccardo Borzuola, Martina Parrella, Giovanna Borriello, Francesco Sica, Fabrizia Monteleone, Elisabetta Maida, Andrea Macaluso
(1) Background : Neuromuscular electrical stimulation (NMES) has beneficial effects on physical functions in Multiple sclerosis (MS) patients. However, the neurophysiological mechanisms underlying these functional improvements are still unclear. This study aims at comparing acute responses in spinal excitability, as measured by soleus Hoffmann reflex (H-reflex), between MS patients and healthy individuals, under three experimental conditions involving the ankle planta flexor muscles: (1) passive NMES (pNMES); (2) NMES superimposed onto isometric voluntary contraction (NMES+); and (3) isometric voluntary contraction (ISO)...
January 25, 2024: Journal of Clinical Medicine
https://read.qxmd.com/read/38333316/neurological-complications-of-influenza-vaccination-navigating-the-spectrum-with-a-focus-on-acute-disseminated-encephalomyelitis-adem
#38
REVIEW
Yusra Mashkoor, Abdullah Nadeem, Tehreem Fatima, Minahil Aamir, Laiba I Vohra, Ashna Habib, Afsheen Khan, Nahid Raufi, Alexander Habte
INTRODUCTION: Acute disseminated encephalomyelitis (ADEM) is a rare neurological disorder characterized by inflammation in the brain and spinal cord. This systematic review aims to investigate the potential association between ADEM and influenza vaccination by analyzing relevant case reports. ADEM is traditionally thought to be a monophasic condition, predominantly affecting children, often following viral illnesses or immunizations. Recent attention has focused on a possible link between ADEM and influenza vaccination, prompting the need for a thorough investigation...
February 2024: Annals of Medicine and Surgery
https://read.qxmd.com/read/38329300/photos-sculpt-the-stories-of-youth-using-photovoice-to-holistically-capture-the-lived-experiences-and-pain-of-youth-who-underwent-spinal-fusion-surgery
#39
JOURNAL ARTICLE
Samantha Noyek, Gillian Newman, Abbie Jordan, Kathryn A Birnie, Melanie Noel
Spinal fusion surgery is one of the most common major surgical procedures in youth. Adolescent idiopathic scoliosis (AIS) is the most frequent reason for corrective spinal fusion. AIS (∼25%-47% of cases) and spinal fusion surgeries are associated with pain, including the development of new onset chronic pain for up to 15% of youth. This research used photovoice approaches to explore the journeys of youth from before, during, and after spinal fusion surgery, to demonstrate their experiences both of and beyond pain...
February 8, 2024: Qualitative Health Research
https://read.qxmd.com/read/38328255/motor-neurons-are-dispensable-for-the-assembly-of-a-sensorimotor-circuit-for-gaze-stabilization
#40
Dena Goldblatt, Başak Rosti, Kyla R Hamling, Paige Leary, Harsh Panchal, Marlyn Li, Hannah Gelnaw, Stephanie Huang, Cheryl Quainoo, David Schoppik
Sensorimotor reflex circuits engage distinct neuronal subtypes, defined by precise connectivity, to transform sensation into compensatory behavior. Whether and how motor neuron populations specify the subtype fate and/or sensory connectivity of their pre-motor partners remains controversial. Here, we discovered that motor neurons are dispensable for proper connectivity in the vestibular reflex circuit that stabilizes gaze. We first measured activity following vestibular sensation in premotor projection neurons after constitutive loss of their extraocular motor neuron partners...
January 27, 2024: bioRxiv
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