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https://www.readbyqxmd.com/read/28641524/the-bio-psycho-social-dimension-in-women-s-sexual-desire-argumentum-ad-novitatem
#1
Nur Syazwani Roslan, Nik Ruzyanei Nik Jaafar, Hatta Sidi, Najwa Baharuddin, Jaya Kumar, Srijit Das, Nik Hazlina Nik Hussein
Sexual desire includes complex motivation and drive. In the context of biological and cognitive-emotive state art of science, it is often a neglected field in medicine. With regard to the treatment, study on women's sexual function received less attention compared to the men's sexuality. In the past, this endeavor was relatively not well disseminated in the scientific community. Recently, there was a revolutionized surge of drug targets available to treat women with low sexual desire. It is timely to review the relevant biological approach, especially in the context of pharmacotherapy to understand this interesting clinical entity which was modulated by numerous interactive psychosocial inter-play and factors...
June 21, 2017: Current Drug Targets
https://www.readbyqxmd.com/read/28629455/an-investigation-of-the-relationship-between-autonomy-childbirth-practices-and-obstetric-fistula-among-women-in-rural-lilongwe-district-malawi
#2
Julika Ayla Kaplan, Jonathan Kandodo, Joseph Sclafani, Susan Raine, Jennifer Blumenthal-Barby, Alison Norris, Abigail Norris-Turner, Elly Chemey, John Michael Beckham, Zara Khan, Reginald Chunda
BACKGROUND: Obstetric fistula is a childbirth injury caused by prolonged obstructed labor that results in destruction of the tissue wall between the vagina and bladder. Although obstetric fistula is directly caused by prolonged obstructed labor, many other factors indirectly increase fistula risk. Some research suggests that many women in rural Malawi have limited autonomy and decision-making power in their households. We hypothesize that women's limited autonomy may play a role in reinforcing childbirth practices that increase the risk of obstetric fistula in this setting by hindering access to emergency care and further prolonging obstructed labor...
June 19, 2017: BMC International Health and Human Rights
https://www.readbyqxmd.com/read/28627296/sexual-violation-of-patients-by-physicians-a-mixed-methods-exploratory-analysis-of-101-cases
#3
James M DuBois, Heidi A Walsh, John T Chibnall, Emily E Anderson, Michelle R Eggers, Mobolaji Fowose, Hannah Ziobrowski
A mixed-method, exploratory design was used to examine 101 cases of sexual violations in medicine. The study involved content analysis of cases to characterize the physicians, patient-victims, the practice setting, kinds of sexual violations, and consequences to the perpetrator. In each case, a criminal law framework was used to examine how motives, means, and opportunity combined to generate sexual misconduct. Finally, cross-case analysis was performed to identify clusters of causal factors that explain specific kinds of sexual misconduct...
June 1, 2017: Sexual Abuse: a Journal of Research and Treatment
https://www.readbyqxmd.com/read/28627033/silodosin-versus-naftopidil-in-the-treatment-of-premature-ejaculation-a-prospective-multicenter-trial
#4
Yoshikazu Sato, Toshikazu Otani, Toshiyasu Amano, Tohru Araki, Nobuyuki Kondou, Masanori Matsukawa, Musashi Tobe, Kazunori Haga, Kousuke Uchida, Ichiya Honma
OBJECTIVES: To determine the efficacy of two α1-adrenoceptor antagonists with different affinities for α1-adrenoceptor subtypes, silodosin and naftopidil, in the treatment of premature ejaculation. METHODS: This was a prospective, open-label, multicenter trial. A total of 26 patients with untreated acquired premature ejaculation were enrolled. Premature ejaculation was defined based on the International Society for Sexual Medicine recommendation. Patients self-administered on demand silodosin 4 mg or naftopidil 25 mg 1 h before intercourse, alternating drugs at least three times each...
June 18, 2017: International Journal of Urology: Official Journal of the Japanese Urological Association
https://www.readbyqxmd.com/read/28622405/implementing-a-randomized-controlled-trial-through-a-community-academia-partnered-participatory-research-arte-con-salud-research-informed-intervention
#5
Patricia Noboa-Ortega, Wanda I Figueroa-Cosme, Alana Feldman-Soler, Christine Miranda-Díaz
OBJECTIVE: "Arte con Salud" is an HIV/AIDS prevention intervention tailored for Puerto Rican women who have sex with men. The intervention curriculum was refined through a community-academic collaboration between Taller Salud, the UPRCayey Campus, and the UCC-School of Medicine, subsided in 2012-13 by PRCTRC. The collaboration has been crucial to validate the impact of using art as a tool to facilitate sexual negotiation skills and safer sexual practices among adult women have sex with men participating in HIV prevention education...
June 2017: Puerto Rico Health Sciences Journal
https://www.readbyqxmd.com/read/28606081/isolation-of-anti-mycobacterial-compounds-from-curtisia-dentata-burm-f-c-a-sm-curtisiaceae
#6
Victor O Fadipe, Nkoana I Mongalo, Andy R Opoku, Preachers M Dikhoba, Tshepiso J Makhafola
BACKGROUND: Tuberculosis is counted amongst the most infectious and lethal illnesses worldwide and remains one of the major threats to human health. The aim of the current study was to isolate and characterize anti-mycobacterial compounds present in Curtisia dentata (Burm.f.) C.A.Sm , a medicinal plant reportedly used in the treatment of tuberculosis, stomach ailments and sexually transmitted infections. METHODS: The bioassay guided principle was followed to isolate the anti-mycobacterial compounds...
June 12, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28596070/sm%C3%A2-sm-the-interface-of-systems-medicine-and-sexual-medicine-for-facing-non-communicable-diseases-in-a-gender-dependent-manner
#7
REVIEW
Emmanuele A Jannini
INTRODUCTION: Complex non-communicable diseases (NCDs), including cancer, cardiovascular disease, obesity, diabetes, and chronic respiratory disorders, are major causes of morbidity and mortality globally. The complexity of NCDs requires innovative, integrated, and interdisciplinary approaches for diagnosis, treatment, and prevention by adopting the new paradigm called systems medicine. A growing body of evidence suggests that sexual dysfunction in general and erectile and lubrication dysfunctions in particular are, in a sex-dependent manner, efficient predictors of overall systemic well-being...
June 5, 2017: Sexual Medicine Reviews
https://www.readbyqxmd.com/read/28596011/emmenagogue-properties-of-milicia-excelsa-welw-c-c-berg-moraceae-based-at-least-in-part-on-its-ability-to-correlate-the-activity-of-the-hypothalamic-pituitary-axis-to-that-of-the-ovaries
#8
Marie Alfrede Mvondo, Aude Jaelle Touomo Sakock, Sylvin Benjamin Ateba, Charline Florence Awounfack, Telesphore Nanbo Gueyo, Dieudonné Njamen
ETHNOPHARMACOLOGICAL RELEVANCE: Milicia excelsa (Welw.) C.C. Berg (Moraceae) is a medicinal plant recommended over tropical Africa as a cure for several ailments including amenorrhea. This is the hallmark of an ovarian lesion or a dysfunction of the hypothalamic-pituitary-ovarian axis which may lead to infertility, osteoporosis or endometrial cancer. However, regardless these traditional claims, no scientific report dealing with emmenagogue properties has been reported yet. AIM OF THE STUDY: To bring scientific evidence to the curative action of the plant, we proposed evaluating the effects of a root aqueous extract of Milicia excelsa on female Wistar rat sexual maturation...
June 6, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28591373/-vulnerability-to-hiv-infection-in-serodiscordant-couples-in-rio-de-janeiro-brazil
#9
Nilo Martinez Fernandes, Élida Azevedo Hennington, Jefferson de Souza Bernardes, Beatriz G Grinsztejn
A new era in HIV/AIDS treatment began in 1996 with the advent of highly active antiretroviral therapy (HAART). The advent of these new medicines expanded the treatment resources and improved life expectancy and quality of life for persons living with HIV and AIDS, favoring the maintenance and initiation of relationships between partners with discordant HIV serological status. The main objective of this study with serodiscordant couples was to understand the three dimensions of vulnerability - programmatic, social, and individual - in these couples...
June 1, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28591093/testicular-cancer-update
#10
Nabil Adra, Lawrence H Einhorn
The advances seen in the treatment of testicular cancer are among the great achievements in modern medicine. These advances were made possible by the collaborative efforts of cancer researchers around the world. Investigators have been able to address many questions regarding the treatment of patients with disease limited to the testis, those with metastasis to the retroperitoneum only, and those with advanced metastatic disease. Questions answered include the chemotherapeutic agents to be used and in what combinations, the proper intensity of treatment and appropriate dosing, the optimal number of cycles of chemotherapy according to validated risk stratification, appropriate surgical approaches that preserve sexual function, the treatment of relapsed disease, what supportive care measures to take, and survivorship issues following treatment of testicular cancer...
May 2017: Clinical Advances in Hematology & Oncology: H&O
https://www.readbyqxmd.com/read/28589384/the-use-of-nutraceuticals-in-male-sexual-and-reproductive-disturbances-position-statement-from-the-italian-society-of-andrology-and-sexual-medicine-siams
#11
A E Calogero, A Aversa, S La Vignera, G Corona, A Ferlin
No abstract text is available yet for this article.
June 6, 2017: Journal of Endocrinological Investigation
https://www.readbyqxmd.com/read/28588639/elephantorrhiza-elephantina-traditional-uses-phytochemistry-and-pharmacology-of-an-important-medicinal-plant-species-in-southern-africa
#12
REVIEW
Alfred Maroyi
Elephantorrhiza elephantina is used in southern Africa as traditional remedy for a wide range of human diseases and ailments including dermatological diseases, gastrointestinal system disorders, sexual dysfunction, sexually transmitted infections, and wounds. The rhizome decoction of E. elephantina is widely used by small-scale farmers in Botswana and South Africa as ethnoveterinary medicine for cattle, goats, horses, pigs, poultry, and sheep. Several classes of phytochemical compounds including anthocyanidins, anthraquinones, esters, fatty acids, phenolic compounds, flavonoids, glycosides, polysterols, saponins, sugars, tannins, and triterpenoids have been isolated from E...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28585846/-czech-linguistic-validation-of-the-pelvic-organ-prolapse-urinary-incontinence-sexual-questionnaire-iuga-revised
#13
Z Rušavý, P Nečesalová, E Rinnová, M Smažinka, M Havíř, V Kališ
OBJECTIVE: To produce a Czech version of a validated tool for sexual quality of life assessment among women with pelvic floor disorders; PISQ-IR (Pelvic organ prolapse/Incontinence Sexual Questionnaire - Internationally Revised). DESIGN: Original study. SETTING: Department of Obstetrics and Gynecology, University Hospital and Faculty of Medicine, Charles University in Pilsen. METHODS: The whole process of translation and linguistic validation of the questionnaire followed the protocol of the International Urogynecology Association developed for this purpose...
2017: Ceská Gynekologie
https://www.readbyqxmd.com/read/28585105/physical-complementary-and-alternative-medicine-in-the-treatment-of-pelvic-floor-disorders
#14
REVIEW
Alex Arnouk, Elise De, Alexandra Rehfuss, Carin Cappadocia, Samantha Dickson, Fei Lian
PURPOSE OF REVIEW: The purpose of the study was to catalog the most recent available literature regarding the use of conservative measures in treatment of pelvic floor disorders. RECENT FINDINGS: Pelvic floor disorders encompass abnormalities of urination, defecation, sexual function, pelvic organ prolapse, and chronic pain, and can have significant quality of life implications for patients. Current guidelines recommend behavioral modifications and conservative treatments as first-line therapy for pelvic floor disorders...
June 2017: Current Urology Reports
https://www.readbyqxmd.com/read/28574774/differing-experiences-with-pre-exposure-prophylaxis-in-boston-among-lesbian-gay-bisexual-and-transgender-specialists-and-generalists-in-primary-care-implications-for-scale-up
#15
Douglas S Krakower, Norma C Ware, Kevin M Maloney, Ira B Wilson, John B Wong, Kenneth H Mayer
The Centers for Disease Control and Prevention estimates that one in four sexually active men who have sex with men (MSM) could decrease their HIV risk by using HIV pre-exposure prophylaxis (PrEP). Because many MSM access healthcare from primary care providers (PCPs), these clinicians could play an important role in providing access to PrEP. Semistructured qualitative interviews were conducted with 31 PCPs in Boston, MA, to explore how they approach decisions about prescribing PrEP to MSM and their experiences with PrEP provision...
June 2, 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28560941/thyroid-cancer-has-a-small-impact-on-patient-partner-relationships-and-their-frequency-of-sexual-activity
#16
Natalie Büel-Drabe, Hans Steinert, Hanspeter Moergeli, Steffi Weidt, Annina Seiler, Josef Jenewein
OBJECTIVE: This cross-sectional survey examined changes in perceived relationships and sexual activity in a sample of thyroid cancer patients and their partners, taking into account sociodemographic and disease-related variables, as well as such outcome measures as anxiety, depression, fatigue, and quality of life (QoL). METHOD: A total of 38 patients with thyroid cancer who were being treated at the department of nuclear medicine in Zürich or Lucerne over the preceding seven years, as well as their partners, completed questionnaires about the quality of their relationships (RQ), about perceptions of changes in their relationships, and about their frequency of sexual activity...
May 31, 2017: Palliative & Supportive Care
https://www.readbyqxmd.com/read/28559416/in-vitro-expansion-of-mouse-primordial-germ-cell-like-cells-recapitulates-an-epigenetic-blank-slate
#17
Hiroshi Ohta, Kazuki Kurimoto, Ikuhiro Okamoto, Tomonori Nakamura, Yukihiro Yabuta, Hidetaka Miyauchi, Takuya Yamamoto, Yukiko Okuno, Masatoshi Hagiwara, Kenjiro Shirane, Hiroyuki Sasaki, Mitinori Saitou
The expansion of primordial germ cells (PGCs), the precursors for the oocytes and spermatozoa, is a key challenge in reproductive biology/medicine. Using a chemical screening exploiting PGC-like cells (PGCLCs) induced from mouse embryonic stem cells (ESCs), we here identify key signaling pathways critical for PGCLC proliferation. We show that the combinatorial application of Forskolin and Rolipram, which stimulate cAMP signaling via different mechanisms, expands PGCLCs up to ~50-fold in culture. The expanded PGCLCs maintain robust capacity for spermatogenesis, rescuing the fertility of infertile mice...
May 30, 2017: EMBO Journal
https://www.readbyqxmd.com/read/28552105/acacia-karroo-hayne-ethnomedicinal-uses-phytochemistry-and-pharmacology-of-an-important-medicinal-plant-in-southern-africa
#18
REVIEW
Alfred Maroyi
Acacia karroo (A. karroo) has been used as herbal medicine by the indigenous people of southern Africa for several centuries. The potential of A. karroo as herbal medicine, its associated phytochemistry and biological activities are reviewed. The extensive literature survey revealed that A. karroo is traditionally used to treat or manage 32 and five human and animal diseases and ailments, respectively. The species is used as herbal medicine for diseases and ailments such as colds, diarrhoea, dysentery, flu, malaria, sexually transmitted infections (STIs), wounds, and also as colic and ethnoveterinary medicine...
April 2017: Asian Pacific Journal of Tropical Medicine
https://www.readbyqxmd.com/read/28546660/can-we-deliver-better
#19
REVIEW
Ajay Rane, Jay Iyer, Harsha Ananthram, Thomas Currie
Human childbirth has been described as an "obstetrical dilemma". Evolution favours enlargement of the foetal brain, whilst bipedal locomotion demands a reduction in pelvic breadth for improvements in biomechanical efficiency. The result of this conflict is a human pelvis incongruous with the dynamics of childbirth. Acute genital distortion at delivery can inflict lasting damage to female pelvic function. Pelvic organ prolapse, urinary, faecal incontinence and sexual dysfunction are long-term sequelae rarely discussed at antenatal care, impacting upon the expectant mother's ability to make an informed decision...
June 2017: Journal of Obstetrics and Gynaecology of India
https://www.readbyqxmd.com/read/28532649/condom-availability-in-schools-a-practical-approach-to-the-prevention-of-sexually-transmitted-infection-hiv-and-unintended-pregnancy
#20
(no author information available yet)
Adolescents and young adults are highly impacted by sexually transmitted infections (STIs) and unplanned pregnancy in the United States and globally. Consistent and correct use of male latex condoms is associated with protection against both STIs and pregnancy. Providing adolescents and young adults with access to free condoms in schools may increase the use of condoms by improving condom availability, eliminating cost, and decreasing embarrassment associated with purchasing condoms. Studies demonstrate that condom availability in schools is associated with the increased use of condoms and improved overall sexual health...
June 2017: Journal of Adolescent Health: Official Publication of the Society for Adolescent Medicine
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