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https://www.readbyqxmd.com/read/27921061/acute-liver-failure-secondary-to-hemophagocytic-lymphohistiocytosis-during-pregnancy
#1
Jeanne-Marie Giard, Kerry A Decker, Jennifer C Lai, Ryan M Gill, Aaron C Logan, Oren K Fix
Hemophagocytic lymphohistiocytosis (HLH) is a syndrome of excessive immune activation that mimics and occurs with other systemic diseases. A 35-year-old female presented with signs of viral illness at 13 weeks of pregnancy and progressed to acute liver failure (ALF). We discuss the diagnosis of HLH and Kikuchi-Fujimoto (KF) lymphadenitis in the context of pregnancy and ALF. HLH may respond to comorbid disease-specific therapy, and more toxic treatment can be avoided.
August 2016: ACG Case Reports Journal
https://www.readbyqxmd.com/read/27904829/systemic-kikuchi-fujimoto-disease-bordering-lupus-lymphadenitis-a-fresh-look
#2
Aram Behdadnia, Seyyed Farshad Allameh, Mehrnaz Asadi Gharabaghi, Seyed Reza Najafizadeh, Ahmad Tahamoli Roudsari, Alireza Ghajar, Morsaleh Ganji, Mohsen Afarideh
A 31-year old woman with persistent fever for 6 weeks and unresponsive to antibiotic therapy came for rheumatologic investigation. After computed tomography (CT) studies of her neck, thorax and abdomen revealed bilateral cervical, axillary and retroperitoneal lymph node enlargements, histopathologic evaluation of the resected nodes showed features of histiocytic necrotizing lymphadenopathy suggestive of Kikuchi-Fujimoto's lymphadenopathy. Kikuchi-Fujimoto Disease (KFD) involving the retroperitoneal nodes is extremely unusual and even more challenging to diagnose when there are no early signs of extranodal involvement or abdominopelvic pain...
November 2016: Intractable & Rare Diseases Research
https://www.readbyqxmd.com/read/27843864/bilateral-painful-parotid-lumps-and-a-lump-in-the-groin-an-uncommon-presentation-of-common-kikuchi-s-disease
#3
Sumeet Prakash Mirgh, Jinendra Satiya, Jehangir Soli Sorabjee
Kikuchi-Fujimoto disease (KFD) is an under-recognized disease most commonly presenting with cervical lymphadenopathy, fever, and cytopenias in young females. Bilateral parotid enlargement is usually caused by infections (e.g., mumps) and autoimmune conditions (e.g., Sjogren syndrome). Parotid enlargement, inguinal lymphadenopathy, and pyrexia of unknown origin are uncommon presenting features of KFD and should be suspected in the appropriate setting.
April 2016: Journal of Family Medicine and Primary Care
https://www.readbyqxmd.com/read/27818025/kikuchi-fujimoto-disease-as-a-differential-diagnosis-for-lymph-nodetuberculosis-the-first-case-of-kikuchi-fujimoto-disease-in-peru
#4
Jorge Nelson Chung Ching
No abstract text is available yet for this article.
November 3, 2016: Archivos de Bronconeumología
https://www.readbyqxmd.com/read/27777431/kikuchi-fujimoto-disease-complicated-with-reactive-hemophagocytic-lymphohistiocytosis
#5
Masatake Nishiwaki, Hideharu Hagiya, Toru Kamiya
Kikuchi-Fujimoto disease (KFD) is a benign cause of self-limiting subacute necrotizing lymphadenitis. KFD is rarely complicated with reactive hemophagocytic lymphohistiocytosis (HLH), and the clinical features of the simultaneous occurrence of these conditions are uncertain. A 30-year-old Japanese man with a persistent fever and sore throat presented to our hospital for treatment. Laboratory analysis showed bicytopenia, and radiological studies showed systemic lymphadenopathy accompanied by splenomegaly. A bone marrow examination showed hemophagocytic macrophages, suggesting HLH...
October 2016: Acta Medica Okayama
https://www.readbyqxmd.com/read/27735163/kikuchi-fujimoto-s-disease-clinicopathological-correlation
#6
Sainath K Andola, Anshuman Sinha, Sangram Biradar
Kikuchi-Fujimoto's disease is a benign, self-limiting disorder characterized by regional tender lymphadenopathy fever and night sweats. It most commonly affects Asian adult females younger than 40 years of age. We report a case of 26 year female who presented with cervical lymphadenopathy, which on FNAC revealed Necrotizing Granulomatous inflammation which was unresponsive for three months of antitubercular therapy. A diagnosis of Kikuchi Fujimoto's disease was suggested on review of the slides at our institute and a biopsy confirmed the diagnosis...
May 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27728446/kikuchi-fujimoto-disease-a-rare-case-with-unusual-etiology
#7
Khavatkopp C, Khanpet Ms
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27727947/kikuchi-fujimoto-disease
#8
Vathsala Lakshmi A, Krishna Prasad A, Shetty M, Narendra Amvr, Ravi Chandra
No abstract text is available yet for this article.
January 2016: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/27696314/-lymphadenitis-and-systemic-lupus-erythematosus
#9
H Merwald-Fraenk, F Wiesent, R Dörfler, C Goebel
A 25-year-old Caucasian female patient presented with fever and cervical lymphadenopathy. Laboratory findings showed elevated signs of inflammation, elevated ANA titer and strongly positive anti-dsDNA antibodies. The histopathology of the lymph nodes revealed distinct features of Kikuchi-Fujimoto disease, a benign, self-limiting lymphadenopathy that typically affects young Asian females. In the literature a coincidental occurrence of Kikuchi-Fujimoto disease and systemic lupus erythematosus (SLE) is well documented...
December 2016: Zeitschrift Für Rheumatologie
https://www.readbyqxmd.com/read/27433383/recurrent-kikuchi-s-disease-treated-by-hydroxychloroquine
#10
Miri Hyun, In Tae So, Hyun Ah Kim, Hyera Jung, Seong-Yeol Ryu
Kikuchi-Fujimoto disease (KFD) is a benign, self-limiting disease, with a specific histopathology. It can be diagnosed clinically, and specific symptoms include fever and cervical lymphadenopathy. The histological finding of KFD in cervical lymph nodes includes necrotizing lymphadenitis. KFD needs conservative treatments. If KFD persists for a long period, steroids or nonsteroidal antiinflammatory drugs can be used to control symptoms. Previous studies have reported the treatment of KFD with hydroxychloroquine (HC) in patients unresponsive to steroids...
June 2016: Infection & Chemotherapy
https://www.readbyqxmd.com/read/27420799/recurrent-bilateral-anterior-uveitis-with-kikuchi-fujimoto-disease
#11
Marta Gómez-Mariscal, Andrea Oleñik, Pablo Arriba-Palomero, Mónica García-Cosio, Francisco J Muñoz-Negrete
PURPOSE: To report an uncommon case of Kikuchi-Fujimoto disease-associated-uveitis. METHODS: A 31-year-old Caucasian woman with cervical lymphadenitis and Kikuchi-Fujimoto disease recently confirmed by biopsy, complained about unilateral blurry vision. Differential diagnoses, including non-Hodgkin lymphoma, tuberculosis, sarcoidosis, Behçet disease, rheumatoid arthritis, and juvenile idiopathic arthritis was performed. We undertook a review of other similar cases found in the literature...
July 15, 2016: Ocular Immunology and Inflammation
https://www.readbyqxmd.com/read/27418858/kikuchi-fujimoto-disease-and-systemic-lupus-erythematosus
#12
Diego F Baenas, Fernando A Diehl, María J Haye Salinas, Verónica Riva, Ana Diller, Pablo A Lemos
Kikuchi-Fujimoto disease, or histiocytic necrotizing lymphadenitis, is an infrequent idiopathic disorder. It has been associated with autoimmune disorders, of which systemic lupus erythematosus is the most outstanding. The basis of its diagnosis relies on the histological examination of lymph nodes, which typically reveals necrosis surrounded by histiocytes with crescentic nucleus, immunoblasts and plasma cells, and absence of neutrophils. We report the case of a 27-year-old Argentinian female patient without any relevant past medical history to demonstrate the correlation between Kikuchi-Fujimoto disease and systemic lupus erythematosus...
2016: International Medical Case Reports Journal
https://www.readbyqxmd.com/read/27408688/case-report-kikuchi-fujimoto-disease-a-diagnostic-and-therapeutic-dilemma-following-pretransplant-nephrectomy-for-a-2-35-kg-kidney
#13
Arvind P Ganpule, Jaspreet Singh Chabra, Abhishek G Singh, Gopal R Tak, Shailesh Soni, Ravindra Sabnis, Mahesh Desai
Kikuchi-Fujimoto disease (KFD) is an extremely rare disease with a worldwide distribution and higher prevalence in Asians. It is a benign and self-limiting disorder, characterized by regional cervical lymphadenopathy accompanied with mild fever and night sweats. Lymph node histopathology is diagnostic and treating physicians should be aware of this entity as it may mimic other systemic diseases like systemic lupus erythematosus, tuberculosis, malignant lymphoma, and more rarely adenocarcinoma. Key features on lymph node biopsy are fragmentation, necrosis and karyorrhexis...
2016: F1000Research
https://www.readbyqxmd.com/read/27389558/characteristic-distribution-pattern-of-cd30-positive-cytotoxic-t-cells-aids-diagnosis-of-kikuchi-fujimoto-disease
#14
Tetsuya Tabata, Katsuyoshi Takata, Tomoko Miyata-Takata, Yasuharu Sato, Shin Ishizawa, Tomoyoshi Kunitomo, Keina Nagakita, Nobuhiko Ohnishi, Kohei Taniguchi, Mai Noujima-Harada, Yoshinobu Maeda, Mitsune Tanimoto, Tadashi Yoshino
INTRODUCTION: Histiocytic necrotizing lymphadenitis (or Kikuchi-Fujimoto disease) frequently occurs in Asian young adult females and typically presents as cervical lymphadenopathy with unknown etiology. Although large immunoblasts frequently appear in Kikuchi-Fujimoto disease, the diffuse infiltration of these cells can cause difficulty in establishing a differential diagnosis from lymphoma. In such cases, CD30 immunostaining may be used; however, the extent or distribution pattern of CD30-positive cells in Kikuchi-Fujimoto disease remains largely unknown...
July 6, 2016: Applied Immunohistochemistry & Molecular Morphology: AIMM
https://www.readbyqxmd.com/read/27317565/kikuchi-fujimoto-disease-an-uncommon-cause-of-neck-swelling
#15
Maria Luisa Fiorella, Matteo Gelardi, Andrea Marzullo, Elena Sabattini, Raffaele Fiorella
Kikuchi-Fujimoto's disease (KFD) is a rare, benign condition characterized by histiocytic necrotizing lymphadenitis predominantly in the cervical region and prolonged fever. It has a higher prevalence in the Japanese and Asian populations although it may be seen in a wide geographic distribution, but rare are the cases reported in Europe. While symptoms resolve spontaneously between 2 weeks and 2 months, complications are described in: CNS, eyes, respiratory tract, kidney and liver. KFD also described an association with systemic lupus erythematosus...
June 17, 2016: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/27293275/kikuchi-fujimoto-disease-the-masquerading-menace-a-rare-case-report
#16
Rohit Kataria, Pankaj Rao, Dilip Kachhawa, Vinod K Jain, Rajat K Tuteja, Manish Vijayvargiya
Kikuchi-Fujimoto disease (KFD) or histiocytic necrotizing lymphadenitis is a rare, benign, self-limiting disease with unknown etiology characterized by regional lymphadenopathy. A 30-year-old female presented with fever, weakness, multiple joint pain, oral ulcers, erythematous facial rashes, hemorrhagic crusting on both lips, and cervical lymphadenopathy of 2-month duration. Clinically, the disease was mimicking systemic lupus erythematosus, but immunofluorescence was negative for it. Lymph node biopsy suggested a diagnosis of KFD...
May 2016: Indian Journal of Dermatology
https://www.readbyqxmd.com/read/27277328/kikuchi-disease-with-generalized-lymph-node-spleen-and-subcutaneous-involvement-detected-by-fluorine-18-fluorodeoxyglucose-positron-emission-tomography-computed-tomography
#17
Alshaima Alshammari, Evangelia Skoura, Nafisa Kazem, Rasha Ashkanani
Kikuchi-Fujimoto disease, known as Kikuchi disease, is a rare benign and self-limiting disorder that typically affects the regional cervical lymph nodes. Generalized lymphadenopathy and extranodal involvement are rare. We report a rare case of a 19-year-old female with a history of persistent fever, nausea, and debilitating malaise. Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT) revealed multiple hypermetabolic generalized lymph nodes in the cervical, mediastinum, axillary, abdomen and pelvic regions with diffuse spleen, diffuse thyroid gland, and focal parotid involvement, bilaterally...
June 5, 2016: Molecular Imaging and Radionuclide Therapy
https://www.readbyqxmd.com/read/27207311/kikuchi-fujimoto-disease-a-diagnostic-dilemma
#18
REVIEW
Laju M Mathew, Rajendra Kapila, Robert A Schwartz
Kikuchi-Fujimoto disease is a benign, self-limiting condition characterized by lymphadenopathy and fever. Its diagnosis can be challenging, as the disease must be differentiated from lymphoma and systemic lupus erythematosus. Patients can present with nonspecific cutaneous lesions. Adequate clinical and histopathologic correlation can aid in the timely diagnosis of Kikuchi's disease, thus preventing the use of unnecessary diagnostic procedures and inappropriate treatments.
October 2016: International Journal of Dermatology
https://www.readbyqxmd.com/read/27179280/histiocytic-necrotising-lymphadenitis-in-mediastinum-mimicking-thymoma-or-lymphoma-case-presentation-and-literature-review-of-kikuchi-fujimoto-disease
#19
REVIEW
P Błasiak, M Jeleń, A Rzechonek, M Marciniak, K Pawełczyk, J Cianciara, J Kołodziej, B Muszczyńska-Bernhard
Kikuchi Fujimoto disease (KFD) as a rare self-limiting lymphadenopathy of short and benign course concerns most frequently the lymph nodes of the neck. The most common symptoms are painfulness of the diseased area, fever and night sweating. The etiology is not well understood, but in the role of pathogenesis viral, autoimmune and genetic factors are taken into account. In the presented case of 37-year-old female it was necessary to exclude diseases such as lymphoma or thymoma because of atypical mediastinal location of Kikuchi Fujimoto disease...
March 2016: Polish Journal of Pathology: Official Journal of the Polish Society of Pathologists
https://www.readbyqxmd.com/read/27162693/an-uncommon-presentation-of-kikuchi-fujimoto-disease-as-mediastinal-lymphadenopathy
#20
Haruaki Hino, Takashi Nishimura, Jun-Ichi Nitadori, Shigesaburo Miyakoshi, Atsuko Seki, Tomio Arai, Jun Nakajima
We experienced an uncommon presentation of Kikuchi-Fujimoto disease (KFD) with sole mediastinal lymphadenopathy in senior age, which was histologically diagnosed by thoracoscopic biopsy leading to appropriate therapy. A 69-year-old man was admitted due to intermittent high fever, general malaise, and appetite loss lasting over 3 months along with 10-kg weight loss in 6 months. Chest computed tomography (CT) showed isolated mediastinal lymphadenopathy, and malignant diseases including malignant lymphoma or metastatic carcinoma, tuberculous lymphadenitis, and sarcoidosis were considered...
May 2016: Journal of Thoracic Disease
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