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https://www.readbyqxmd.com/read/29458056/alcohol-and-cv-health-jekyll-and-hyde-j-curves
#1
REVIEW
Evan L O'Keefe, James J Di Nicolantonio, James H O'Keefe, Carl J Lavie
A routine of light or moderate alcohol consumption (≤1 drink/day for women and 1 to 2 drinks/day for men) were associated with a lower risk for all-cause mortality, coronary artery disease (CAD), type 2 diabetes mellitus (T2D), heart failure (HF), and stroke. Conversely, heavy drinking, (>4 drinks/day) is associated with an increased risk for death and cardiovascular (CV) disease (CVD). Excessive alcohol intake trails behind only smoking and obesity among the 3 leading causes of premature deaths in the United States (US)...
February 16, 2018: Progress in Cardiovascular Diseases
https://www.readbyqxmd.com/read/29456869/cognitive-fluctuations-in-parkinson-s-disease-dementia-blood-pressure-lability-as-an-underlying-mechanism
#2
David E Riley, Alberto J Espay
Background: Cognitive fluctuations refer to alterations in cognition, attention, or arousal occurring over minutes to hours, most commonly in patients with dementias associated with advanced Lewy body pathology. Their pathophysiologic underpinning remains undetermined. Case presentation: We documented serial blood pressure (BP) measurements in an 86-year-old man with Parkinson's disease dementia experiencing cognitive fluctuations during an office visit. This patient's associated dysautonomia included labile BP with orthostatic hypotension and nocturnal hypertension...
2018: Journal of Clinical Movement Disorders
https://www.readbyqxmd.com/read/29456380/moxibustion-artemisia-plant-at-acupuncture-point-as-alternative-therapy-in-hypertension-a-promising-approach
#3
Mohammad Jamshed Siddiqui, Mohamad Fadly Bin Kamarudin, Abdul Kareem Mohammed Al-Shami, Siti Zaiton Mat So'ad, Shazia Qasim Jamshed
Hypertension is a pathological condition in which the blood pressure is higher than under normal physiological conditions, i.e., 140/90 mmHg or higher. Blood pressure is measured as the force exerted by the blood pumped by the heart against the walls of arteries (aorta) and distributed throughout the body. Use of complementary and alternative medicine as a cure for hypertension is a common phenomenon because of the high risk of cardiovascular complications and kidney diseases caused by conventional Western medicine...
October 2017: Journal of Pharmacy & Bioallied Sciences
https://www.readbyqxmd.com/read/29455792/left-ventricular-structure-and-diastolic-function-by-cardiac-magnetic-resonance-imaging-in-hypertrophic-cardiomyopathy
#4
Binita Riya Chacko, Gauri R Karur, Kim A Connelly, Raymond T Yan, Anish Kirpalani, Rachel Wald, Laura Jimenez-Juan, John Roshan Jacob, Djeven P Deva, Andrew T Yan
OBJECTIVE: Diastolic dysfunction is common in hypertrophic cardiomyopathy (HCM) and hypertensive heart disease (HHD), but its relationships with left ventricular (LV) parameters have not been well studied. Our objective was to assess the relationship of various measures of diastolic function, and maximum left ventricular wall thickness (MLVWT) and left ventricular mass index (LVMI) in HCM, HHD and normal controls using cardiac magnetic resonance imaging (CMR). We also assessed LV parameters and diastolic function in relation to late gadolinium enhancement (LGE) and right ventricular (RV) hypertrophy in HCM...
January 2018: Indian Heart Journal
https://www.readbyqxmd.com/read/29454617/antihypertensive-potential-of-linalool-and-linalool-complexed-with-%C3%AE-cyclodextrin-effects-of-subchronic-treatment-on-blood-pressure-and-vascular-reactivity
#5
Samuel Barbosa Camargo, Letícia Oliveira Simões, Carla Fiama de Azevedo Medeiros, Anderson de Melo Jesus, Josmara Bartolomei Fregoneze, Afrânio Evangelista, Cristiane Flora Villarreal, Adriano Antunes de Souza Araújo, Lucindo José Quintans-Júnior, Darizy Flavia Silva
Linalool (LIN) is a monoterpene alcohol present in some aromatic medicinal plants with biological activities that can impact cardiovascular diseases. This chemical class is highly volatile and β-cyclodextrin (β-CD) has been employed to improve the pharmacological properties of monoterpenes. Thus, the aim of this study was to evaluate the cardiovascular effects of LIN free focusing on the antihypertensive properties of this monoterpene and to study whether LIN, complexed in β-cyclodextrin (LIN-βCD) is able to improve the pharmacological activity of LIN...
February 15, 2018: Biochemical Pharmacology
https://www.readbyqxmd.com/read/29453877/significance-of-mitochondria-on-cardiometabolic-syndromes
#6
REVIEW
Nair Anupama, G Sindhu, K G Raghu
Metabolic syndromes (MS) are a cluster of disorders like obesity, hypertension, dyslipidemia, and diabetes. Cardiometabolic syndrome (CMS), a branch of MS, is a group of diseases affecting cardiovascular, renal, metabolic, prothrombotic and inflammatory abnormalities due to defects in energy metabolism. Since the emergence of molecular biology and the discovery of pathogenic mitochondrial DNA defect in the 1980s, research advances has revealed a number of common human disease involving mitochondrial dysfunction...
February 17, 2018: Fundamental & Clinical Pharmacology
https://www.readbyqxmd.com/read/29453020/2018-consensus-of-the-taiwan-society-of-cardiology-and-the-diabetes-association-of-republic-of-china-taiwan-on-the-pharmacological-management-of-patients-with-type-2-diabetes-and-cardiovascular-diseases
#7
Chern-En Chiang, Shih-Yi Lin, Tsung-Hsien Lin, Tzung-Dau Wang, Hung-I Yeh, Jung-Fu Chen, Chia-Ti Tsai, Yi-Jen Hung, Yi-Heng Li, Ping-Yen Liu, Kuan-Cheng Chang, Kang-Ling Wang, Ting-Hsing Chao, Kou-Gi Shyu, Wei-Shiung Yang, Kwo-Chang Ueng, Pao-Hsien Chu, Wei-Hsian Yin, Yen-Wen Wu, Hao-Min Cheng, Shyi-Jang Shin, Chien-Ning Huang, Lee-Ming Chuang, Shing-Jong Lin, San-Jou Yeh, Wayne Huey-Herng Sheu, Jiunn-Lee Lin
The global incidence and prevalence of type 2 diabetes have been escalating in recent decades. Patients with type 2 diabetes have an increased risk of atherosclerotic cardiovascular disease (ASCVD). About two-thirds of death in type 2 diabetes are due to ASCVD, including 40% from coronary heart disease (CHD), 15% from heart failure (HF), and 10% from stroke. The association between hyperglycemia and elevated CV risk has been demonstrated in multiple cohort studies. However, clinical trials of intensive glucose reduction did not significantly reduce macrovascular outcomes...
February 13, 2018: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/29452887/protein-intake-and-long-term-change-in-glomerular-filtration-rate-in-the-jackson-heart-study
#8
Rakesh Malhotra, Loren Lipworth, Kerri L Cavanaugh, Bessie A Young, Katherine L Tucker, Teresa C Carithers, Herman A Taylor, Adolfo Correa, Edmond K Kabagambe, T Alp Ikizler
OBJECTIVE: Dietary protein intake could have deleterious renal effects in populations at risk for chronic kidney disease. Here, we examined whether higher protein intake (≥80th percentile of energy from protein) is associated with decline in kidney function and whether this decline varies by diabetes status. DESIGN: Observational cohort study. SUBJECTS AND SETTINGS: Participants were African-Americans (n = 5,301), who enrolled in the Jackson Heart Study between 2000 and 2004...
February 13, 2018: Journal of Renal Nutrition
https://www.readbyqxmd.com/read/29451507/-appropriateness-in-cardiology-a-statement-of-the-anmco-veneto-region
#9
Guerrino Zuin, Gianfranco Frigo, Loris Roncon, Aldo Bonso, Emanuele Carbonieri, Fabio Chirillo, Fabio De Conti, Pietro Delise, Alessandro Desideri, Daniele D'Este, Loredano Milani, Roberto Valle, Claudio Bilato
Inappropriate tests are responsible for longer waiting lists, higher economical costs for the National Health System and major clinical risks due to radiation exposure from prescription abuse of diagnostic testing. Clinical inappropriateness frequently derives from poor knowledge of guidelines, "defensive medicine" approach and/or repeat requests of patients and family members. About one third of non-invasive imaging tests are considered inappropriate.In order to define the most appropriate instruments for the follow-up of the most common cardiovascular diseases with the highest risk of inappropriateness, all the cardiologists of the Veneto Region (Italy), along with the local chapters of the main national cardiology societies and general practitioners have been involved by the Regional Section of the Italian Association of Hospital Cardiologists (ANMCO) in several scientific meetings on the following topics: hypertension, chronic ischemic heart disease, valvular heart disease, heart failure, and atrial fibrillation...
January 2018: Giornale Italiano di Cardiologia
https://www.readbyqxmd.com/read/29451048/impact-of-radon-and-combinatory-radon-carbon-dioxide-spa-on-pain-and-hypertension-results-from-the-explorative-rad-on01-study
#10
Paul F Rühle, Gerhart Klein, Tatjana Rung, Hong Tiep Phan, Claudia Fournier, Rainer Fietkau, Udo S Gaipl, Benjamin Frey
OBJECTIVES: Therapies with low doses of radon have beneficial effects on patients suffering from chronic painful degenerative and inflammatory diseases. We already showed that this is accompanied by systemic immune modulations. We here focus on pain reducing effects of very low doses of radon by adding carbon dioxide water and its impact on heart rate variability (HRV), blood pressure and free radicals. METHODS: 100 patients receiving radon spa (1.200 Bq/l at 34°C or 600 Bq/l, 1 g/l CO 2 at 34°C) were monitored before and at three different time points after therapy...
February 16, 2018: Modern Rheumatology
https://www.readbyqxmd.com/read/29449707/modulation-of-cardiac-stem-cell-characteristics-by-metoprolol-in-hypertensive-heart-disease
#11
Sherin Saheera, Ajay Godwin Potnuri, Renuka R Nair
Cardiac stem cells (CSCs) play a vital role in cardiac remodeling. Uncontrolled hypertension leads to cardiac hypertrophy, followed by cardiac failure. Pathological remodeling is associated with enhanced oxidative stress. Decreased cardiac stem cell efficiency is speculated in heart diseases. Maintaining a healthy stem cell population is essential for preventing progressive cardiac remodeling. Some anti-hypertensive drugs are cardioprotective. However, the effect of these drugs on CSCs has not been investigated...
February 15, 2018: Hypertension Research: Official Journal of the Japanese Society of Hypertension
https://www.readbyqxmd.com/read/29449364/diabetic-cardiomyopathy-an-update-of-mechanisms-contributing-to-this-clinical-entity
#12
REVIEW
Guanghong Jia, Michael A Hill, James R Sowers
Heart failure and related morbidity and mortality are increasing at an alarming rate, in large part, because of increases in aging, obesity, and diabetes mellitus. The clinical outcomes associated with heart failure are considerably worse for patients with diabetes mellitus than for those without diabetes mellitus. In people with diabetes mellitus, the presence of myocardial dysfunction in the absence of overt clinical coronary artery disease, valvular disease, and other conventional cardiovascular risk factors, such as hypertension and dyslipidemia, has led to the descriptive terminology, diabetic cardiomyopathy...
February 16, 2018: Circulation Research
https://www.readbyqxmd.com/read/29447389/survival-of-adults-with-systemic-autoimmune-rheumatic-diseases-and-pulmonary-arterial-hypertension-after-lung-transplantation
#13
Elana J Bernstein, Joan M Bathon, David J Lederer
Objectives: Pulmonary arterial hypertension (PAH) is a major cause of morbidity and mortality in adults with systemic autoimmune rheumatic diseases (ARDs). The aim of this study was to determine whether adults with ARDs and PAH on right-sided heart catheterization (ARD-PAH) have increased mortality following lung transplantation compared with those with PAH not due to an ARD. Methods: We conducted a retrospective cohort study of 93 adults with ARD-PAH and 222 adults with PAH who underwent lung transplantation in the USA between 4 May 2005 and 9 March 2015 using data from the United Network for Organ Sharing...
February 13, 2018: Rheumatology
https://www.readbyqxmd.com/read/29447246/fried-food-intake-and-risk-of-nonfatal-acute-myocardial-infarction-in-the-costa-rica-heart-study
#14
Peter Hu, Yanping Li, Hannia Campos
Economic development in middle-income countries has led to a noticeable rise in the availability of commercial deep fried foods and lifestyles that require eating meals "on the go" and outside of the home. Yet, data from these countries where fried foods were traditionally prepared at home are scarce, despite several studies showing the potential adverse effects of fried food consumption on risk for heart disease. We aimed to examine whether consumption of fried foods inside or outside of the home is associated with an increased risk of myocardial infarction (MI) among Hispanic/Latinos living in Costa Rica...
2018: PloS One
https://www.readbyqxmd.com/read/29447001/new-2017-american-heart-association-and-american-college-of-cardiology-guideline-for-hypertension-in-the-adults-major-paradigm-shifts-but-will-they-help-to-fight-against-the-hypertension-disease-burden
#15
Michel Burnier, Suzanne Oparil, Krzysztof Narkiewicz, Sverre E Kjeldsen
No abstract text is available yet for this article.
February 15, 2018: Blood Pressure
https://www.readbyqxmd.com/read/29446818/heart-involvement-in-systemic-sclerosis
#16
Ihsen Zairi, Lilia Baili, Khadija Mzoughi, Manel Dridi, Zouhaier Jnifene, Fatma Boussema
INTRODUCTION: Primary and secondary heart involvement in systemic sclerosis are important mortality predictors. Aim of this study was to investigate by standard echocardiography associated to pulsed-tissue Doppler imaging, six-minute walk test (6MWT) and BNP level cardiac manifestation in 30 patients with ScS and to establish a strategy to detect and to evaluate this complication. METHODS: This was a cross-sectional study conducted over a period of 16 months: a total of 30 consecutive patients with ScS diagnosed as proposed by the American college of Rheumatology and the European League Against Rheumatism 2013 and who were hospitalized in Internal Medicine department of Habib Thameur hospital underwent cardiac assessment...
March 2017: La Tunisie Médicale
https://www.readbyqxmd.com/read/29444925/increasing-incidence-and-prevalence-of-world-health-organization-groups-1-to-4-pulmonary-hypertension-a-population-based-cohort-study-in-ontario-canada
#17
D Thiwanka Wijeratne, Katherine Lajkosz, Susan B Brogly, M Diane Lougheed, Li Jiang, Ahmad Housin, David Barber, Ana Johnson, Katharine M Doliszny, Stephen L Archer
BACKGROUND: The World Health Organization recognizes 5 groups of pulmonary hypertension (PH), categorized by pathogenesis or comorbidity: 1-pulmonary arterial hypertension 2-left-heart disease, 3-lung disease and hypoxia 4-chronic thromboembolic disease, and 5-miscellaneous. The epidemiology of PH, apart from group 1, is largely unknown. METHODS AND RESULTS: We describe incidence, prevalence, comorbidities, mortality and prescribing patterns for groups 1 to 4 PH from 1993 to 2012...
February 2018: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/29444773/lung-function-inflammation-and-endothelin-1-in-congenital-heart-disease-associated-pulmonary-arterial-hypertension
#18
Andrew Low, Sarah George, Luke Howard, Nicholas Bell, Ann Millar, Robert M R Tulloh
BACKGROUND: Breathlessness is the most common symptom in people with pulmonary arterial hypertension and congenital heart disease (CHD-APAH), previously thought to be caused by worsening PAH, but perhaps also by inflammation and abnormalities of lung function. We studied lung function and airway inflammation in patients with CHD-APAH and compared the results with controls. METHODS AND RESULTS: Sixty people were recruited into the study: 20 CHD-APAH, 20 CHD controls, and 20 healthy controls...
February 14, 2018: Journal of the American Heart Association
https://www.readbyqxmd.com/read/29443762/incidence-and-risk-factors-for-surgical-site-infection-after-open-reduction-and-internal-fixation-of-ankle-fracture-a-retrospective-multicenter-study
#19
Yaning Sun, Huijuan Wang, Yuchao Tang, Haitao Zhao, Shiji Qin, Lihui Xu, Zhiyong Xia, Fengqi Zhang
Information on surgical site infection (SSI) after surgical treatment of ankle fracture is limited and remains controversial. The purpose of the present study was to determine the incidence and risk factors for SSI after open reduction and internal fixation (ORIF) of ankle fracture. Patients who underwent ORIF for ankle fracture at 3 centers between January 2015 and December 2016 were included. The potential risk factors for SSI included demographic variables, including age, sex, body mass index (BMI), hypertension, diabetes mellitus, heart disease, smoking, and excessive alcohol intake; blood test variables including preoperative white blood cell count, neutrophil count, red blood cell count, hemoglobin, total protein, albumin and globulin; injury- and surgery-related variables, including duration of operation (minutes), intraoperative blood loss, surgeon level, fracture site, accompanied dislocation, use of a drainage tube, and antibiotic use...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29443444/diabetes-and-intracerebral-hemorrhage-baseline-characteristics-and-mortality
#20
Ron Liebkind, Daniel Gordin, Daniel Strbian, Atte Meretoja, Lena M Thorn, Stephanie Hägg-Holmberg, Carol Forsblom, Turgut Tatlisumak, Per-Henrik Groop, Jukka Putaala
BACKGROUND: Acknowledging the conflicting evidence of diabetes as a predictor of short- and long-term mortality following an intracerebral hemorrhage (ICH), we compared baseline characteristics and 30-day and long-term mortality between patients with and without diabetes after an ICH-paying special attention to differences between type 1 (T1D) and type 2 (T2D) diabetes. METHODS: Patients with a first-ever ICH were followed for a median of 2.3 years. Adjusting for demographics, comorbidities and documented ICH characteristics increasing mortality after ICH, logistic regression analysis assessed factors associated with case-fatality and 1-year survival among the 30-day survivors...
February 14, 2018: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
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