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https://www.readbyqxmd.com/read/28527715/influence-of-netrin-1-on-reinnervation-of-laryngeal-muscles-following-recurrent-laryngeal-nerve-injury
#1
Ignacio Hernandez-Morato, Shira Koss, Sansar Sharma, Michael J Pitman
Following recurrent laryngeal nerve (RLN) injury, recovery results in poor functional restitution of the paralyzed vocal fold. Netrin-1 has been found to be upregulated in the rat posterior cricoarytenoid muscle (PCA) during nerve regeneration, We evaluated the effect of ectopic Netrin-1 in the PCA during RLN reinnervation. The right RLN was transected and Netrin-1 was injected into the PCA (2.5, 5, 10, 15, 20μg/ml). At 7 days post injury fluorescent retrograde tracer was injected into PCA and Thyroarytenoid (TA) muscles...
May 17, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28522763/aortic-arch-compliance-and-idiopathic-unilateral-vocal-fold-paralysis
#2
Reza Behkam, Kara E Roberts, Andrew J Bierhals, M Eileen Jacobs, Julia D Edgar, Randal C Paniello, Gayle Woodson, Jonathan P Vande Geest, Julie M Barkmeier-Kraemer
Unilateral vocal fold paralysis (UVP) occurs related to recurrent laryngeal nerve (RLN) impairment associated with impaired swallowing, voice production, and breathing functions. The majority of UVP cases occur subsequent to surgical intervention with approximately 12-42% having no known cause for the disease (i.e., idiopathic). Approximately 2/3 of those with UVP exhibit left-sided injury with the average onset at 50 years of age or older in those diagnosed as idiopathic. Given the association between the RLN and the subclavian and aortic arch vessels, we hypothesized that changes in vascular tissues would result in increased aortic compliance in idiopathic left-sided UVP patients compared to those without UVP...
May 18, 2017: Journal of Applied Physiology
https://www.readbyqxmd.com/read/28503988/the-usefulness-of-narrow-band-imaging-for-the-diagnosis-and-treatment-of-vocal-fold-leukoplakia
#3
Fang Huang, Jinchao Yu, Fan Zhang, Changding He, Shimin Li, Jun Shao
OBJECTIVE: This research was aimed to explore the efficacy of narrow-band imaging (NBI) on distinguishing the degree of dysplasia of vocal fold leukoplakia. METHODS: Patients were examined by flexible endoscopy, under white light endoscopy (WLE) and NBI. 78 lesions were divided into two groups according to the NBI classification. Group 1: non-dysplasia (ND), including squamous hyperplasia with hyperkeratosis or parakeratosis; Group 2: squamous hyperplasia with mild or moderate dysplasia (MD) or severe dysplasia (SD), or carcinoma in situ (CIS)...
May 14, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28499735/turkish-standardized-reading-passage-for-the-evaluation-of-hard-glottal-attack-occurrence-frequency
#4
Melek Nur Uygun, Fatma Esen Aydınlı, Songül Aksoy, Esra Özcebe
OBJECTIVE: This study aimed to develop a Turkish reading passage that can be used in evaluating the frequency of hard glottal attack (HGA) and to assess its reliability. STUDY DESIGN: This is a prospective case-control study. METHODS: The Towne-Heuer reading passage is a valuable tool that can be used for the auditory-perceptual assessment of voice. The characteristics of the first four paragraphs of the reading passage were analyzed by a linguist...
May 9, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28495329/dynamics-of-the-driving-force-during-the-normal-vocal-fold-vibration-cycle
#5
Philippe Henri DeJonckere, Jean Lebacq, Ingo R Titze
Intraglottal pressure is the driving force of vocal fold vibration. Theoretically, simultaneous quantification of glottal area and transglottal airflow allows the calculation of the intraglottal pressure waveform during a single vibration cycle. In this study, we show that, by combining photoglottography (transglottal light transmission) and airflow (Rothenberg mask) measurements during sustained vocal emissions in vivo, the intraglottal pressure wave can be approximated in a way similar to what has been done in models...
May 8, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28495327/vocal-change-patterns-during-a-teaching-day-inter-and-intra-subject-variability
#6
Angélique Remacle, Maëva Garnier, Silvain Gerber, Claire David, Caroline Petillon
OBJECTIVES: The study aimed to describe the average response of 22 female teachers to vocal fatigue during a workday, to examine their inter- and intra-subject variability, and to establish a typology of different responses to vocal fatigue. METHODS: Fundamental frequency (F0), harmonics-to-noise ratio (HNR), jitter, and shimmer were measured for each participant on sustained vowels at the beginning and at the end of the workday, on three different times of the school year...
May 8, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28493220/continuous-intraoperative-neural-monitoring-in-thyroid-surgery-a-mexican-experience
#7
Karla Verónica Chávez, Jackeline Ramírez, Juan Pablo Pantoja, Mauricio Sierra, David Velázquez-Fernández, Miguel F Herrera
Intraoperative continuous neural monitoring (C-IONM) during thyroid surgery has been recognized as a useful tool to identify and confirm recurrent laryngeal nerve integrity. The aim of the present study is to analyze electromyographic features and thresholds for normal vocal fold function in our initial experience with C-IONM in thyroid surgery. C-IONM was utilized in 57 patients who underwent thyroid surgery between July 2012 and December 2015. EMG parameters were analyzed looking for potential predictors of postoperative vocal fold dismotility...
May 10, 2017: Updates in Surgery
https://www.readbyqxmd.com/read/28492834/apoptosis-and-vocal-fold-disease-clinically-relevant-implications-of-epithelial-cell-death
#8
Carolyn K Novaleski, Bruce D Carter, M Preeti Sivasankar, Sheila H Ridner, Mary S Dietrich, Bernard Rousseau
Purpose: Vocal fold diseases affecting the epithelium have a detrimental impact on vocal function. This review article provides an overview of apoptosis, the most commonly studied type of programmed cell death. Because apoptosis can damage epithelial cells, this article examines the implications of apoptosis on diseases affecting the vocal fold cover. Method: A review of the extant literature was performed. We summarized the topics of epithelial tissue properties and apoptotic cell death, described what is currently understood about apoptosis in the vocal fold, and proposed several possible explanations for how the role of abnormal apoptosis during wound healing may be involved in vocal pathology...
May 10, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28489246/atypical-presentation-of-vocal-fold-granulomas
#9
Raj B Patel, Aaron Jaworek, Robert T Sataloff
No abstract text is available yet for this article.
April 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28485825/new-evidence-of-cutaneous-leishmaniasis-in-north-eastern-italy
#10
V Gaspari, M Ortalli, M P Foschini, C Baldovini, A Lanzoni, R Cagarelli, P Gaibani, G Rossini, C Vocale, R Tigani, G A Gentilomi, C Misciali, S Pesci, A Patrizi, M P Landini, S Varani
BACKGROUND: Human leishmaniasis is on increase the in Mediterranean Europe. However, the exact prevalence of cutaneous leishmaniasis (CL) is largely unknown as underdiagnosis and underreporting are common. OBJECTIVE: To evaluate epidemiological, clinico-pathological and microbiological aspects of CL cases occurring in the Bologna province, north-eastern Italy. METHODS: We performed a retrospective, observational study on CL cases diagnosed in the Bologna province between January 2013 and December 2015...
May 9, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28485294/medialization-thyroplasty-in-glottis-insufficiency-due-to-unilateral-vocal-fold-paralysis-and-after-laser-cordectomies-preliminary-report
#11
Anna Rzepakowska, Ewa Osuch-Wójcikiewicz, Ewelina Sielska-Badurek, Kazimierz Niemczyk
Medialization thyroplasty (type I) is surgical procedure performed on the thyroid cartilage. The major indication for this surgery is significant glottis insufficiency due to unilateral vocal fold paresis. However the proce¬dure is also performed after vocal fold resections during cordectomy. THE AIM: The evaluation of voice results in patients after medialisation throplasty. MATERIAL AND METHODS: In Otolaryngology Department of Medical University of Warsaw there were performed so far 8 thyroplasty procedures under local anaesthesia with implantation of medical silicon protesis...
February 28, 2017: Otolaryngologia Polska
https://www.readbyqxmd.com/read/28483222/endoscopic-management-of-bilateral-vocal-fold-paralysis-in-newborns-and-infants
#12
Sahba Sedaghat, Mario Tapia, Felipe Fredes, Pablo Rojas
INTRODUCTION: Bilateral vocal cord paralysis in adducted position (BVCPAd) is a severe cause of airway obstruction and usually debuts with stridor and airway distress necessitating immediate intervention. Tracheostomy has long been the gold standard for treating this condition, but has significant associated morbidity and mortality in pediatric patients. New conservative procedures have emerged to treat this condition thus avoiding tracheostomy, like endoscopic anterior and posterior cricoid split (EAPCS)...
June 2017: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/28476217/apoptosis-in-vocal-fold-polyps
#13
Abdul-Latif Hamdan, Georges Tabet, Zein Saadeddin, Rachel Btaiche, Ibrahim Khalifeh
OBJECTIVE: To examine the degree of apoptosis and its role in the pathogenesis of polyps of the vocal folds. MATERIAL AND METHOD: A review of the pathology department's archives for patients diagnosed with vocal fold polyps between 2010 and 2016 has been conducted. As a control group, gross and microscopically intact vocal fold from laryngectomy specimens was collected. A total of 61 vocal fold polyps from 51 patients and 41 unremarkable vocal folds from the control group were identified...
May 2, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28476216/potential-causative-factors-for-saccular-disorders-association-with-smoking-and-other-laryngeal-pathologies
#14
Oded Cohen, Sharon Tzelnick, Yael Shapira Galitz, Hagit Shoffel-Havakuk, Moshe Hain, Doron Halperin, Yonatan Lahav
OBJECTIVE: To describe risk factors, clinical presentation, and outcome of patients with saccular disorders. STUDY DESIGN: Case control with chart review METHODS: A single center retrospective study. Case group included all adult patients, presenting with saccular disorders (saccular cyst or laryngocele), between the years 2010 and 2015. A matched group of patients with vocal fold cyst served as the control. RESULTS: Twenty-nine patients met the inclusion criteria: 15 males and 14 females; the mean age was 60...
May 2, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28469139/in-vitro-fibrillogenesis-of-tropocollagen-type-iii-in-collagen-type-i-affects-its-relative-fibrillar-topology-and-mechanics
#15
Meisam Asgari, Neda Latifi, Hossein K Heris, Hojatollah Vali, Luc Mongeau
Tropocollagen types I and III were simultaneously fibrilized in vitro, and the differences between the geometric and mechanical properties of the heterotypic fibrils with different mixing ratios of tropocollagen III to I were investigated. Transmission electron microscopy was used to confirm the simultaneous presence of both tropocollagen types within the heterotypic fibrils. The incorporation of collagen III in I caused the fibrils to be thinner with a shorter D-banding than pure collagen I. Hertzian contact model was used to obtain the elastic moduli from atomic force microscope indentation testing using a force volume analysis...
May 3, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28467509/laryngeal-evidence-for-the-first-and-second-passaggio-in-professionally-trained-sopranos
#16
Matthias Echternach, Fabian Burk, Marie Köberlein, Andreas Selamtzis, Michael Döllinger, Michael Burdumy, Bernhard Richter, Christian Thomas Herbst
INTRODUCTION: Due to a lack of empirical data, the current understanding of the laryngeal mechanics in the passaggio regions (i.e., the fundamental frequency ranges where vocal registration events usually occur) of the female singing voice is still limited. MATERIAL AND METHODS: In this study the first and second passaggio regions of 10 professionally trained female classical soprano singers were analyzed. The sopranos performed pitch glides from A3 (ƒo = 220 Hz) to A4 (ƒo = 440 Hz) and from A4 (ƒo = 440 Hz) to A5 (ƒo = 880 Hz) on the vowel [iː]...
2017: PloS One
https://www.readbyqxmd.com/read/28467327/presbiphonya
#17
Caterina Bruzzi, Daria Salsi, Domenico Minghetti, Maurizio Negri, Delfo Casolino, Michele Sessa
AIM: This article attempts to describe the aging process of the vocal folds and the main features of the aged voice. BACKGROUND: In the world ageing population era, aging diseases and aging disorders are crucial. Voice disorders (presbyphonia) are common in the elderly and have a significant impact on communication and quality of life. Some of these disorders depend on the vocal folds, which consist of an extracellular matrix (ECM), fibrous proteins, interstitial proteins, and glycosaminoglycans...
April 28, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28464670/an-extended-kalman-filter-approach-to-non-stationary-bayesian-estimation-of-reduced-order-vocal-fold-model-parameters
#18
Paul J Hadwin, Sean D Peterson
The Bayesian framework for parameter inference provides a basis from which subject-specific reduced-order vocal fold models can be generated. Previously, it has been shown that a particle filter technique is capable of producing estimates and associated credibility intervals of time-varying reduced-order vocal fold model parameters. However, the particle filter approach is difficult to implement and has a high computational cost, which can be barriers to clinical adoption. This work presents an alternative estimation strategy based upon Kalman filtering aimed at reducing the computational cost of subject-specific model development...
April 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28464635/a-finite-element-study-on-the-cause-of-vocal-fold-vertical-stiffness-variation
#19
Biao Geng, Qian Xue, Xudong Zheng
A finite element method based numerical indentation technique was used to quantify the effect of the material stiffness variation and the subglottal convergence angle of the vocal fold on the vertical stiffness difference of the medial surface. It was found that the vertical stiffness difference increased with the increasing subglottal angle, and it tended to saturate beyond a subglottal angle of about 50°. The material stiffness variation could be as important as the subglottal angle depending on the actual material properties...
April 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28462766/vocal-fold-paresis-a-debilitating-and-underdiagnosed-condition
#20
G Harris, C O'Meara, C Pemberton, J Rough, P Darveniza, S Tisch, I Cole
OBJECTIVES: To review the clinical signs of vocal fold paresis on laryngeal videostroboscopy, to quantify its impact on patients' quality of life and to confirm the benefit of laryngeal electromyography in its diagnosis. METHODS: Twenty-nine vocal fold paresis patients were referred for laryngeal electromyography. Voice Handicap Index 10 results were compared to 43 patients diagnosed with vocal fold paralysis. Laryngeal videostroboscopy analysis was conducted to determine side of paresis...
May 2, 2017: Journal of Laryngology and Otology
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