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https://www.readbyqxmd.com/read/28647731/recovery-of-vocal-fold-epithelium-after-acute-phonotrauma
#1
Bernard Rousseau, Tsuyoshi Kojima, Carolyn K Novaleski, Emily E Kimball, Carla V Valenzuela, Masanobu Mizuta, James J Daniero, C Gaelyn Garrett, M Preeti Sivasankar
We investigated the timeline of tissue repair of vocal fold epithelium after acute vibration exposure using an in vivo rabbit model. Sixty-five New Zealand white breeder rabbits were randomized to 120 min of modal- or raised-intensity phonation. After the larynges were harvested at 0, 4, 8, and 24 h, and at 3 and 7 days, the vocal fold tissue was evaluated using electron microscopy and quantitative real-time polymerase chain reaction. There was an immediate decrease in the microprojection depth and height following raised-intensity phonation, paired with upregulation of cyclooxygenase-2...
June 24, 2017: Cells, Tissues, Organs
https://www.readbyqxmd.com/read/28647431/temporal-segmentation-for-laryngeal-high-speed-videoendoscopy-in-connected-speech
#2
Maryam Naghibolhosseini, Dimitar D Deliyski, Stephanie R C Zacharias, Alessandro de Alarcon, Robert F Orlikoff
OBJECTIVE: This study proposes a gradient-based method for temporal segmentation of laryngeal high-speed videoendoscopy (HSV) data obtained during connected speech. METHODS: A custom-developed HSV system coupled with a flexible fiberoptic nasolaryngoscope was used to record one vocally normal female participant during reading of the "Rainbow Passage." A gradient-based algorithm was developed to generate a motion window. When applied to the HSV data, the motion window acted as a filter tracking the location of the vibrating vocal folds...
June 21, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28643583/hemodynamic-stability-during-laryngeal-electromyography-procedures
#3
Yi-An Lu, Yu-Cheng Pei, Alice Mk Wong, Hui-Chen Chiang, Tuan-Jen Fang
BACKGROUND: Laryngeal electromyography (LEMG) is accepted as safe, with minimal side effects. However, patient hemodynamic stability, during these procedures, has not been reported. This study aimed to investigate the hemodynamics in patients undergoing LEMG and determine the risk factors for hemodynamic changes. METHODS: We recruited 89 consecutive patients who underwent LEMG. Baseline and postprocedural changes in vital signs were analyzed. RESULTS: Diastolic blood pressure (DBP) increased from 75...
June 23, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28638932/-treatment-of-recurrent-laryngeal-nerve-paralysis
#4
A H Müller
Whereas static vocal fold medialization or lateralization are currently the standard procedures, new dynamic treatment methods such as reinnervation and laryngeal pacing focus on better toning and remobilization of the paralyzed vocal folds. End-to-end or jump anastomoses of the recurrent laryngeal nerve can preserve muscle mass and avoid atrophy, thus enabling subsequent dynamic therapeutic options. Prognostic evaluation and the time point of therapeutic intervention are important issues in the management of patients with recurrent laryngeal nerve paralysis...
June 20, 2017: HNO
https://www.readbyqxmd.com/read/28636732/positron-emission-tomography-enhancement-after-vocal-fold-injection-medialization
#5
Nazaneen Grant, Richard J Wong, Dennis H Kraus, Heiko Schoder, Ryan C Branski
The potential for the misinterpretation of positron-emission tomography (PET) scans in the context of a possible malignancy has been confirmed in a case report showing increased 18F-fluorodeoxyglucose (FDG) uptake after unilateral vocal fold augmentation medialization. We sought to expand these findings by investigating FDG uptake in a larger cohort of patients via a retrospective chart review. We examined the records of 15 adults-8 men and 7 women-who had undergone vocal fold augmentation for unilateral vocal fold paralysis and at least one subsequent PET scan...
June 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28636727/vocal-fold-hemorrhage-into-a-physiologic-sulcus
#6
Daniel A Benito, Jonathan J Romak, Robert T Sataloff
No abstract text is available yet for this article.
June 2017: Ear, Nose, & Throat Journal
https://www.readbyqxmd.com/read/28635301/stem-cell-mediated-paracrine-signaling-alters-fibroplasia-in-human-vocal-fold-fibroblasts-in-vitro
#7
Nao Hiwatashi, Renjie Bing, Iv Kraja, Ryan C Branski
OBJECTIVES: Interactions between mesenchymal stem cells (MSCs) and native vocal fold fibroblasts (VFFs) have not been described in spite of promising preliminary data regarding the effects of MSCs on vocal fold repair in vivo. The current study employed a conditioned media (CM) model to investigate the paracrine effects of bone marrow-derived mesenchymal stem cells (BMSCs) on VFFs. METHODS: Human VFFs were treated with transforming growth factor-β1 (TGF-β1; 10 ng/mL), CM from human BMSCs following 48 hours of TGF-β1 stimulation, or CM+TGF-β1...
June 1, 2017: Annals of Otology, Rhinology, and Laryngology
https://www.readbyqxmd.com/read/28633959/characterization-of-the-superior-olivary-complex-of-canis-lupus-domesticus
#8
Tatiana Fech, Lilian Calderón-Garcidueñas, Randy J Kulesza
The superior olivary complex (SOC) is a collection of brainstem auditory nuclei which play essential roles in the localization of sound sources, temporal coding of vocalizations and descending modulation of the cochlea. Notwithstanding, the SOC nuclei vary considerably between species in accordance with the auditory needs of the animal. The canine SOC was subjected to anatomical and physiological examination nearly 50 years ago and was then virtually forgotten. Herein, we aimed to characterize the nuclei of the canine SOC using quantitative morphometrics, estimation of neuronal number, histochemistry for perineuronal nets and immunofluorescence for the calcium binding proteins calbindin and calretinin...
June 15, 2017: Hearing Research
https://www.readbyqxmd.com/read/28624315/coexisting-vocal-fold-polyps-and-sulcus-vocalis-coincidence-or-coexistence-characteristics-of-14-patients
#9
Narin Nard Carmel-Neiderman, Oshri Wasserzug, Tomer Ziv-Baran, Yael Oestreicher-Kedem
OBJECTIVE: The study aimed (1) to evaluate the prevalence of sulcus vocalis (SV) coexisting with vocal fold polyp (SV-VFP), and (2) to determine the effect of their coexistence on voice quality. STUDY DESIGN: This is a retrospective cohort study in a tertiary referral center. METHODS: The medical records of all patients who underwent micro direct laryngoscopy due to VFPs between January 2013 and April 2015 were reviewed. Patients with SV-VFP were identified and data of their demographics, medical history, habits, preoperative and intraoperative laryngeal findings, and pre- and postoperative GRBAS (Grade, Roughness, Breathiness, Asthenia, Strain) score, and compared with the data of patients with solitary VFPs (S-VFPs)...
June 14, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28622836/safety-assessment-of-the-use-of-ultrasonic-energy-in-the-proximity-of-the-recurrent-laryngeal-nerve-in-a-porcine-model
#10
Karla V Chávez, Elpidio M Barajas, Francisco Soroa, Armando Gamboa-Dominguez, Samuel Ordóñez, Juan P Pantoja, Mauricio Sierra, David Velázquez-Fernández, Miguel F Herrera
BACKGROUND: Advanced bipolar and ultrasonic energy have demonstrated reduction of operating time and blood loss in thyroidectomy. However, these devices generate heat and thermal dispersion that may damage adjacent structures such as the recurrent laryngeal nerve (RLN). This study was designed to evaluate the safety profile of the Harmonic Focus+(®) (HF+) device through the evaluation of thermal injury to the RLN using different algorithms of distance and time with state of the art technology...
June 7, 2017: American Journal of Surgery
https://www.readbyqxmd.com/read/28622494/laryngeal-neuropathy-in-adult-goats-with-copper-deficiency
#11
R F A Sousa, V M Almeida, J E Neto, C W A Nascimento, G X Medeiros, R M T Medeiros, F Riet-Correa, F S Mendonça
The aim of this study was to elucidate the cause of a neurological syndrome characterized by stridor in adult goats with clinical signs of copper deficiency. The main clinical signs consisted of apathy, emaciation, pale mucous membranes, mucous nasal discharge, dyspnea, severe achromotrichia, diffuse alopecia, torpor, ataxia, and stridor. When the goats were forced to move, the stridor increased. In a herd of 194 Toggenburg goats, 10 adult goats with clinical signs of copper deficiency were removed from the herd and divided into 2 groups: group 1, which consisted of 4 nannies and 1 buck with stridor, and group 2, which consisted of 4 nannies and 1 buck without stridor...
July 2017: Veterinary Pathology
https://www.readbyqxmd.com/read/28618804/an-optical-flow-based-state-space-model-of-the-vocal-folds
#12
Alba Granados, Jonas Brunskog
High-speed movies of the vocal fold vibration are valuable data to reveal vocal fold features for voice pathology diagnosis. This work presents a suitable Bayesian model and a purely theoretical discussion for further development of a framework for continuum biomechanical features estimation. A linear and Gaussian nonstationary state-space model is proposed and thoroughly discussed. The evolution model is based on a self-sustained three-dimensional finite element model of the vocal folds, and the observation model involves a dense optical flow algorithm...
June 2017: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28612098/measurement-of-the-maximum-frequency-of-electroglottographic-fluctuations-in-the-expiration-phase-of-volitional-cough-as-a-functional-test-for-cough-efficiency
#13
Toshihiko Iwahashi, Makoto Ogawa, Kiyohito Hosokawa, Chieri Kato, Hidenori Inohara
The hypotheses of the present study were that the maximum frequency of fluctuation of electroglottographic (EGG) signals in the expiration phase of volitional cough (VC) reflects the cough efficiency and that this EGG parameter is affected by impaired laryngeal closure, expiratory effort strength, and gender. For 20 normal healthy adults and 20 patients diagnosed with unilateral vocal fold paralysis (UVFP), each participant was fitted with EGG electrodes on the neck, had a transnasal laryngo-fiberscope inserted, and was asked to perform weak/strong VC tasks while EGG signals and a high-speed digital image of the larynx were recorded...
June 13, 2017: Dysphagia
https://www.readbyqxmd.com/read/28610317/a-new-species-of-limnonectes-amphibia-anura-dicroglossidae-from-vietnam
#14
Cuong The Pham, Minh Duc Le, Tao Thien Nguyen, Thomas Ziegler, Zheng Jun Wu, Truong Quang Nguyen
A new species of Limnonectes is described from northeastern Vietnam based on morphological and molecular differences. Morphologically, the new species is distinguishable from its congeners on the basis of a combination of the following diagnostic characters: Large size (SVL 50.1-68.9 in males, 45.5-63.0 mm in females); males with moderately enlarged head (HL/SVL 0.48), head longer than wide; vomerine teeth present; external vocal sacs absent; rostral length short (RL/SVL 0.16 in males, 0.15 in females); tympanum distinct (TD/ED 0...
May 24, 2017: Zootaxa
https://www.readbyqxmd.com/read/28608475/the-natural-history-of-recoverable-vocal-fold-paralysis-implications-for-kinetics-of-reinnervation
#15
Ted Mau, Hao-Min Pan, Lesley F Childs
OBJECTIVES/HYPOTHESIS: Patients with unilateral vocal fold paralysis (UVFP) are commonly told to wait 12 months for spontaneous recovery. This study aims to 1) determine the time to vocal recovery in UVFP, 2) use that data to develop a neurophysiologically plausible model for recovery, and 3) use the model to generate meaningful predictions for patient counseling. STUDY DESIGN: Case series with de novo mathematical modeling. METHODS: Patients with UVFP who could pinpoint a discrete onset of vocal improvement were identified...
June 13, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28608401/the-anatomical-evolution-of-the-thyroid-cartilage-from-childhood-to-adulthood-a-computed-tomography-evaluation
#16
Eran Glikson, Doron Sagiv, Ana Eyal, Michael Wolf, Adi Primov-Fever
OBJECTIVE: To enhance knowledge and understanding of the laryngeal framework maturation in different age groups and genders. STUDY DESIGN: Cohort imaging study. SETTING: Tertiary academic referral center. METHODS: Computed tomography neck scans of 283 patients aged 8 to 20 years were studied. The interlaminae angle (ILA) of the thyroid cartilage at the level of the vocal folds, the anterior projection (angulation) of the thyroid cartilage (TC), and the degree of calcifications were evaluated and compared in sequential age groups of both genders...
June 13, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28606663/changes-after-voice-therapy-in-acoustic-voice-analysis-of-chinese-patients-with-voice-disorders
#17
Dan Lu, Fei Chen, Hui Yang, Rong Yu, Qi Zhou, Xinyuan Zhang, Jia Ren, Yitao Zheng, Xiaoyan Zhang, Jian Zou, Haiyang Wang, Jun Liu
OBJECTIVES: This study aimed to evaluate the effects of voice therapy on patients with voice disorders by comparing the acoustic parameter changes before and after treatment. STUDY DESIGN: This is a retrospective study. METHODS: Forty-five female patients with early-stage vocal nodules or polyps, postoperative patients, and patients with chronic laryngitis were divided into three subgroups. Videostroboscopic, acoustic analysis (fundamental frequency, jitter, shimmer, mean harmonics-to-noise ratio), and maximum phonation time (MPT) were measured before and after treatment...
June 9, 2017: Journal of Voice: Official Journal of the Voice Foundation
https://www.readbyqxmd.com/read/28605818/-phonomicrosurgery-a-retrospective-analysis-of-400-cases
#18
Rudolf Reiter, Thomas Hoffmann
Introduction Voice disorders caused by pseudotumors of the vocal folds or paralysis of the vocal folds with incomplete glottis closure frequently require phonomicrosurgery. These interventions were analyzed with regard to quality of voice after surgery and safety of the intervention. Methods Retrospective analysis of 400 consecutive phonomicrosurgery interventions. The following parameters were collected: distribution of pathologies of the vocal folds, rating of the voice quality by both the surgeon (RBH-system) and patient and videolaryngstroboscopy six weeks after the intervention compared to the state prior to surgery, complications and results of histological examination...
June 12, 2017: Laryngo- Rhino- Otologie
https://www.readbyqxmd.com/read/28600598/recurrence-of-vocal-fold-leukoplakia-after-carbon-dioxide-laser-therapy
#19
Min Chen, Jian Chen, Lei Cheng, Haitao Wu
This work aims to analyze the recurrence of vocal fold leukoplakia after carbon dioxide (CO2) laser resection. In this retrospective study, all patients undergoing CO2 laser resection of vocal fold leukoplakia were followed up for at least 2 years. Recurrence was diagnosed as any presence of leukoplakia in the vocal cord subsequent to previous successful complete resection. A total of 326 patients with complete resection of vocal fold leukoplakia and follow-up subsequent surveillance laryngoscopy were studied...
June 9, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/28599995/effects-of-vertical-glottal-duct-length-on-intraglottal-pressures-and-phonation-threshold-pressure-in-the-uniform-glottis
#20
Sheng Li, Ronald C Scherer, Lewis P Fulcher, Xianbo Wang, Lijun Qiu, Mingxi Wan, Supin Wang
According to Titze's 1988 derivations for phonation threshold pressure (PTP), there are a number of important variables that PTP depends upon. A primary one is the vertical glottal duct length T: PTP decreases if T is increased. Changing the length of T, however, may have a significant effect on other variables that PTP depends upon. This study examined the effects of lengthening the vertical uniform glottal duct on the transglottal and intraglottal pressures, and the derived transglottal pressure coefficients, for five glottal diameters (0...
June 6, 2017: Journal of Voice: Official Journal of the Voice Foundation
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