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https://www.readbyqxmd.com/read/29238507/kinetic-parameters-and-nitrate-nitrite-changes-in-bioremediation-of-toxic-pentaerythritol-tetranitrate-petn-contaminated-soil
#1
Mohsen Sadani, Mohammad Amin Karami, Fahimeh Teimouri, Mohammad Mehdi Amin, Seyed Mahdi Moosavi, Bahare Dehdashti
Background: Cleanup of areas contaminated by explosives is a public health concern. Some explosives can be carcinogenic in humans. Pentaerythritol Tetranitrate (PETN), a powerful explosive with very low water solubility, can be easily transported to ground waters. Objective: This study was conducted to determine the removal efficiencies of PETN from soil by bioremediation, and obtain kinetic parameters of biological process. Methods: This experimental study was conducted at the Environmental Health Engineering Lab (Isfahan University of Medical Sciences, Isfahan, Iran) in 2015-2016...
October 2017: Electronic Physician
https://www.readbyqxmd.com/read/29216185/a-cyber-linked-undergraduate-research-experience-in-computational-biomolecular-structure-prediction-and-design
#2
Rebecca F Alford, Andrew Leaver-Fay, Lynda Gonzales, Erin L Dolan, Jeffrey J Gray
Computational biology is an interdisciplinary field, and many computational biology research projects involve distributed teams of scientists. To accomplish their work, these teams must overcome both disciplinary and geographic barriers. Introducing new training paradigms is one way to facilitate research progress in computational biology. Here, we describe a new undergraduate program in biomolecular structure prediction and design in which students conduct research at labs located at geographically-distributed institutions while remaining connected through an online community...
December 2017: PLoS Computational Biology
https://www.readbyqxmd.com/read/29201138/implementation-and-use-of-cloud-based-electronic-lab-notebook-in-a-bioprocess-engineering-teaching-laboratory
#3
Erin M Riley, Holly Z Hattaway, P Arthur Felse
Background: Electronic lab notebooks (ELNs) are better equipped than paper lab notebooks (PLNs) to handle present-day life science and engineering experiments that generate large data sets and require high levels of data integrity. But limited training and a lack of workforce with ELN knowledge have restricted the use of ELN in academic and industry research laboratories which still rely on cumbersome PLNs for recordkeeping. We used LabArchives, a cloud-based ELN in our bioprocess engineering lab course to train students in electronic record keeping, good documentation practices (GDPs), and data integrity...
2017: Journal of Biological Engineering
https://www.readbyqxmd.com/read/29198107/fingerprint-analysis-moving-toward-multi-attribute-determination-via-individual-markers
#4
Erica Brunelle, Crystal Huynh, Eden Alin, Morgan Eldridge, Anh Minh Le, Lenka Halámková, Jan Halámek
Forensic science will be forever revolutionized if law enforcement can identify personal attributes of a person of interest solely from a fingerprint. For the past 2 years, the goal of our group was to establish a way to identify originator attributes, specifically biological sex, from a single analyte. To date, an enzymatic assay and two chemical assays have been developed for the analysis of multiple analytes. In this manuscript, two additional assays have been developed. This time, however, the assays utilize only one amino acid each...
December 2, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/29196472/first-person-ana-nascimento
#5
(no author information available yet)
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Ana Nascimento is the first author on 'KIF13A mediates trafficking of influenza A virus ribonucleoproteins', published in Journal of Cell Science. Ana conducted the work in this article in Maria João Amorim's lab at the Instituto Gulbenkian de Ciência, Portugal. She is now a PhD student in the lab of Beate Sodeik at the Institute of Virology at Hannover Medical School, investigating host-pathogen interactions, particularly involving viruses...
December 1, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/29196471/first-person-lai-kuan-dionne-and-eric-peterman
#6
(no author information available yet)
First Person is a series of interviews with the first authors of a selection of papers published in Journal of Cell Science, helping early-career researchers promote themselves alongside their papers. Lai Kuan Dionne and Eric Peterman are co-first authors on 'FYCO1 regulates accumulation of post-mitotic midbodies by mediating LC3-dependent midbody degradation', published in Journal of Cell Science. Lai Kuan Dionne is a post-doctoral associate in the lab of Moe Mahjoub at Washington University School of Medicine, investigating the molecular mechanisms of post-mitotic midbody accumulation and secretion in health and diseases...
December 1, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/29196425/providing-social-support-for-underrepresented-racial-and-ethnic-minority-phd-students-in-the-biomedical-sciences-a-career-coaching-model
#7
Simon N Williams, Bhoomi K Thakore, Richard McGee
Improvement in the proportion of underrepresented racial and ethnic minorities (URMs) in academic positions has been unsatisfactory. Although this is a complex problem, one key issue is that graduate students often rely on research mentors for career-related support, the effectiveness of which can be variable. We present results from a novel academic career "coaching" intervention, one aim of which was to provide supplementary social support for PhD students, particularly those from underrepresented backgrounds...
2017: CBE Life Sciences Education
https://www.readbyqxmd.com/read/29194464/computer-aided-biomarker-discovery-for-precision-medicine-data-resources-models-and-applications
#8
Yuxin Lin, Fuliang Qian, Li Shen, Feifei Chen, Jiajia Chen, Bairong Shen
Biomarkers are a class of measurable and evaluable indicators with the potential to predict disease initiation and progression. In contrast to disease-associated factors, biomarkers hold the promise to capture the changeable signatures of biological states. With methodological advances, computer-aided biomarker discovery has now become a burgeoning paradigm in the field of biomedical science. In recent years, the 'big data' term has accumulated for the systematical investigation of complex biological phenomena and promoted the flourishing of computational methods for systems-level biomarker screening...
November 29, 2017: Briefings in Bioinformatics
https://www.readbyqxmd.com/read/29174066/a-flexible-control-system-designed-for-lab-scale-simulations-and-optimization-of-composting-processes
#9
Sh Oazana, M Naor, J Grinshpun, I Halachmi, M Raviv, I Saadi, R Avidov, V Sudharsan Varma, L Rosenfeld, A Gross, Y Laor
Understanding and optimization of composting processes can benefit from the use of controlled simulators of various scales. The Agricultural Research Organization Composting Simulator (ARO-CS) was recently built and it is flexibly automated by means of a programmable logic controller (PLC). Temperature, carbon dioxide, oxygen and airflow are monitored and controlled in seven 9-l reactors that are mounted into separate 80-l water baths. The PLC program includes three basic heating modes (pre-determined temperature profile, temperature-feedback ("self-heating"), and carbon dioxide-dependent temperature), three basic aeration modes (airflow dependence on temperature, carbon dioxide, or oxygen) and enables all possible combinations among them...
November 21, 2017: Waste Management
https://www.readbyqxmd.com/read/29157569/a-regional-consortium-for-doctor-of-nursing-practice-education-integrating-improvement-science-into-the-curriculum
#10
Shea Polancich, Linda Roussel, Barbara Ann Graves, Pamela V O'Neal
The DNP curriculum prepares the graduate for evidence informed improvement translation through coursework integrating improvement, safety, and translation sciences. Innovative leadership skills are necessary to lead inter-professional unit-based and health system opportunities. Equipping the DNP with the necessary skills and competencies to accomplish any type of improvement translation requires exposure to the tools and techniques of these sciences with an emphasis in didactic content. With a foundational knowledge of the principles for improvement, translation and application will follow...
November 2017: Journal of Professional Nursing: Official Journal of the American Association of Colleges of Nursing
https://www.readbyqxmd.com/read/29140488/us-national-cancer-institute-china-collaborative-studies-on-chinese-medicine-and-cancer
#11
Libin Jia, Hongsheng Lin, Joost Oppenheim, O M Zack Howard, Jie Li, Huiting Fan, Zhizheng Zhao, William Farrar, Ying Zhang, Nancy Colburn, Matthew R Young, Weidong Li, David Newman, Barry R O'Keefe, John Beutler, Jikai Liu, Xiaojiang Hao, Xiaosheng Yang, Tengfei Ji, Jeffrey D White
Since 2007, the US National Cancer Institute (NCI) Office of Cancer Complementary and Alternative Medicine (OCCAM), together with the Cancer Institute of the China Academy of Chinese Medical Sciences (CICACMS), institutes at China Academy of Sciences and Chinese Academy of Medical Sciences, have engaged in collaborations on Chinese medicine (CM) and cancer research. Through these collaborations, CM drugs and compounds have been studied at NCI labs. This paper summarizes the discoveries and progress on these research projects, exploring the aspects of cancer prevention, botanical drug mechanisms of action and component analysis/quality control (QC), and anticancer activity screening...
November 1, 2017: Journal of the National Cancer Institute. Monographs
https://www.readbyqxmd.com/read/29131508/an-interactive-computer-lab-of-the-galvanic-cell-for-students-in-biochemistry
#12
Emma Ahlstrand, Antoine Buetti-Dinh, Ran Friedman
We describe an interactive module that can be used to teach basic concepts in electrochemistry and thermodynamics to first year natural science students. The module is used together with an experimental laboratory and improves the students' understanding of thermodynamic quantities such as Δr G, Δr H, and Δr S that are calculated but not directly measured in the lab. We also discuss how new technologies can substitute some parts of experimental chemistry courses, and improve accessibility to course material...
November 13, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/29114234/gender-specific-covariations-between-competencies-interest-and-effort-during-science-learning-in-virtual-environments
#13
Eva Christophel, Wolfgang Schnotz
Women are still underrepresented in engineering courses although some German universities offer separate women's engineering courses which include virtual STEM learning environments. To outline information about fundamental aspects relevant for virtual STEM learning, one has to reveal which similarities both genders in virtual learning show. Moreover, the question arises as to whether there are in fact differences in the virtual science learning of female and male learners. Working with virtual STEM learning environments requires strategic and arithmetic-operative competences...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29104438/-my-naturesound-nature-observations-with-sound-recordings
#14
Veljo Runnel, Marko Peterson, Allan Zirk
Background: Online systems for observation reporting by citizen scientists have been operating for many years. iNaturalist (California Academy of Sciences 2016), eBird (Cornell Lab of Ornithology 2016) and Observado (Observation International 2016) are well-known international systems, Artportalen (Swedish Species Information Centre 2016) and Artsobservasjoner (Norwegian Biodiversity Information Centre 2016) are Scandinavian. In addition, databases and online solutions exist that are more directly research-oriented but still offer participation by citizen scientists, such as the PlutoF (University of Tartu Natural History Museum 2016) platform...
2017: Biodiversity Data Journal
https://www.readbyqxmd.com/read/29102857/can-infants-learn-phonology-in-the-lab-a-meta-analytic-answer
#15
Alejandrina Cristia
Two of the key tasks facing the language-learning infant lie at the level of phonology: establishing which sounds are contrastive in the native inventory, and determining what their possible syllabic positions and permissible combinations (phonotactics) are. In 2002-2003, two theoretical proposals, one bearing on how infants can learn sounds (Maye, Werker, & Gerken, 2002) and the other on phonotactics (Chambers, Onishi, & Fisher, 2003), were put forward on the pages of Cognition, each supported by two laboratory experiments, wherein a group of infants was briefly exposed to a set of pseudo-words, and plausible phonological generalizations were tested subsequently...
November 2, 2017: Cognition
https://www.readbyqxmd.com/read/29097711/trapping-and-manipulation-of-nanoparticles-using-multifocal-optical-vortex-metalens
#16
Yanbao Ma, Guanghao Rui, Bing Gu, Yiping Cui
Optical trapping and manipulation have emerged as a powerful tool in the biological and physical sciences. In this work, we present a miniature optical tweezers device based on multifocal optical vortex metalens (MOVM). The MOVM is capable of generating multiple focal fields with specific orbital angular momentum at arbitrary position. The optical force of the vortex field exerted on both high-refractive-index particle and low-refractive-index particle are analyzed. The simulation results show that the two kinds of dielectric particles can be trapped simultaneously...
November 6, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29089358/an-interview-with-christiane-n%C3%A3-sslein-volhard
#17
Katherine Brown
Christiane Nüsslein-Volhard is Director Emeritus at the Max Planck Institute for Developmental Biology in Tübingen, Germany. In 1995, she was awarded the Nobel Prize for Physiology and Medicine, along with Eric Wieschaus and Edward Lewis, for her work on the genetic control of embryogenesis using the fruit fly Drosophila melanogaster In the 1990s, she transitioned her lab to working with zebrafish (Danio rerio), using similar forward genetic approaches to those that had proved so successful in Drosophila to uncover key regulators of vertebrate development...
November 1, 2017: Development
https://www.readbyqxmd.com/read/29074231/the-engage-study-integrating-neuroimaging-virtual-reality-and-smartphone-sensing-to-understand-self-regulation-for-managing-depression-and-obesity-in-a-precision-medicine-model
#18
Leanne M Williams, Adam Pines, Andrea N Goldstein-Piekarski, Lisa G Rosas, Monica Kullar, Matthew D Sacchet, Olivier Gevaert, Jeremy Bailenson, Philip W Lavori, Paul Dagum, Brian Wandell, Carlos Correa, Walter Greenleaf, Trisha Suppes, L Michael Perry, Joshua M Smyth, Megan A Lewis, Elizabeth M Venditti, Mark Snowden, Janine M Simmons, Jun Ma
Precision medicine models for personalizing achieving sustained behavior change are largely outside of current clinical practice. Yet, changing self-regulatory behaviors is fundamental to the self-management of complex lifestyle-related chronic conditions such as depression and obesity - two top contributors to the global burden of disease and disability. To optimize treatments and address these burdens, behavior change and self-regulation must be better understood in relation to their neurobiological underpinnings...
October 7, 2017: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29067647/sino-u-s-partnerships-in-research-education-and-patient-care-the-experience-of-the-university-of-pittsburgh-and-upmc
#19
REVIEW
Arthur S Levine, Margaret C McDonald, Charles E Bogosta
In 2011, the University of Pittsburgh School of Medicine (UPSOM) and Tsinghua University formed a partnership to further the education of Tsinghua medical students. These students come to UPSOM as visiting research scholars for two years of their eight-year MD curriculum. During this time, the students, who have completed four years at Tsinghua, work full-time in medical school laboratories and research programs of their choice, essentially functioning as graduate students. In their first two months in Pittsburgh, the scholars have a one-week orientation to biomedical research, followed by two-week rotations in four labs selected on the basis of the scholars' scientific interests, after which they choose one of these labs for the remainder of the two years...
October 23, 2017: Science China. Life Sciences
https://www.readbyqxmd.com/read/29062845/efficacy-of-aloevera-cream-in-the-treatment-of-paederus-dermatitis-in-mice
#20
Ramin Khaghani, Iraj Mirzaii-Dizgah, Mostafa Ghasemi
BACKGROUND: Dermatitis caused by Paederus beetle involves many people around the world, especially Iran. The symptoms include redness, itching and severe irritation. This study evaluated the effectiveness of the Aloevera cream on the treatment of dermatitis caused by Paederus beetles. METHODS: Forty male 6-8 weeks BALB/C mice were randomly divided into four groups of 10 mice. After removing the mice's back hair, the backs of mice were marked by a circle with a diameter of 3 mm...
June 2017: Journal of Arthropod-borne Diseases
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