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https://www.readbyqxmd.com/read/28524117/ebutterfly-leveraging-massive-online-citizen-science-for-butterfly-consevation
#1
Kathleen L Prudic, Kent P McFarland, Jeffrey C Oliver, Rebecca A Hutchinson, Elizabeth C Long, Jeremy T Kerr, Maxim Larrivée
Data collection, storage, analysis, visualization, and dissemination are changing rapidly due to advances in new technologies driven by computer science and universal access to the internet. These technologies and web connections place human observers front and center in citizen science-driven research and are critical in generating new discoveries and innovation in such fields as astronomy, biodiversity, and meteorology. Research projects utilizing a citizen science approach address scientific problems at regional, continental, and even global scales otherwise impossible for a single lab or even a small collection of academic researchers...
May 18, 2017: Insects
https://www.readbyqxmd.com/read/28512334/three-dimensional-scoring-of-zebrafish-behavior-unveils-biological-phenomena-hidden-by-two-dimensional-analyses
#2
Simone Macrì, Daniele Neri, Tommaso Ruberto, Violet Mwaffo, Sachit Butail, Maurizio Porfiri
The study of zebrafish behavior represents a cornerstone upon which basic researchers promise to advance knowledge in life sciences. Although zebrafish swim in a three-dimensional (3D) space, their behavior in the lab is almost exclusively scored in two dimensions, whereby zebrafish are recorded using a single camera providing 2D videos. Whether this dimensional reduction preserves the reliability of data has not been addressed. Here we show that, compared to a 3D observation, 2D data are flawed by over-reporting and under-reporting of locomotory differences...
May 16, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28510572/1-2-million-kids-and-counting-mobile-science-laboratories-drive-student-interest-in-stem
#3
Amanda L Jones, Mary K Stapleton
In today's increasingly technological society, a workforce proficient in science, technology, engineering, and mathematics (STEM) skills is essential. Research has shown that active engagement by K-12 students in hands-on science activities that use authentic science tools promotes student learning and retention. Mobile laboratory programs provide this type of learning in schools and communities across the United States and internationally. Many programs are members of the Mobile Lab Coalition (MLC), a nonprofit organization of mobile and other laboratory-based education programs built on scientist and educator collaborations...
May 2017: PLoS Biology
https://www.readbyqxmd.com/read/28505523/trainers-perception-of-the-learning-environment-and-student-competency-a-qualitative-investigation-of-midwifery-and-anesthesia-training-programs-in-ethiopia
#4
Sharon Kibwana, Rachel Haws, Adrienne Kols, Firew Ayalew, Young-Mi Kim, Jos van Roosmalen, Jelle Stekelenburg
BACKGROUND: Ethiopia has successfully expanded training for midwives and anesthetists in public institutions. This study explored the perceptions of trainers (instructors, clinical lab assistants and preceptors) towards the adequacy of students' learning experience and implications for achieving mastery of core competencies. METHODS: In-depth interviews with 96 trainers at 9 public universities and 17 regional health science colleges across Ethiopia were conducted to elicit their opinions about available resources, program curriculum suitability, and competence of graduating students...
May 1, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28503844/typeloader-a-fast-and-efficient-automated-workflow-for-the-annotation-and-submission-of-novel-full-length-hla-alleles
#5
V Surendranath, V Albrecht, J D Hayhurst, B Schöne, J Robinson, S G E Marsh, A H Schmidt, V Lange
Recent years have seen a rapid increase in the discovery of novel allelic variants of the human leukocyte antigen (HLA) genes. Commonly, only the exons encoding the peptide binding domains of novel HLA alleles are submitted. As a result, the IPD-IMGT/HLA Database lacks sequence information outside those regions for the majority of known alleles. This has implications for the application of the new sequencing technologies, which deliver sequence data often covering the complete gene. As these technologies simplify the characterization of the complete gene regions, it is desirable for novel alleles to be submitted as full-length sequences to the database...
May 14, 2017: HLA
https://www.readbyqxmd.com/read/28494032/radiographic-appearance-of-interocclusal-record-materials-for-cone-beam-computed-tomography-guided-implant-surgeries
#6
Vrinda V Mohunta, Edwin A McGlumphy, Do-Gyoon Kim, Shereen S Azer
PURPOSE: To select an ideal interocclusal record material for cone beam computed tomography (CBCT)-guided implant surgery based on the material's radiodensity on the scan. MATERIALS AND METHODS: Twelve commonly used interocclusal record materials were used for this investigation: two were waxes, one was polyether, and nine were polyvinyl-siloxane-type materials. A scan template was fabricated by duplicating existing dentures in Ortho-Jet acrylic resin mixed with 30% barium powder for the teeth and 10% barium powder for the denture base between the teeth and the tissue...
May 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28469564/pavlovian-conditioning-of-larval-drosophila-an-illustrated-multilingual-hands-on-manual-for-odor-taste-associative-learning-in-maggots
#7
Birgit Michels, Timo Saumweber, Roland Biernacki, Jeanette Thum, Rupert D V Glasgow, Michael Schleyer, Yi-Chun Chen, Claire Eschbach, Reinhard F Stocker, Naoko Toshima, Teiichi Tanimura, Matthieu Louis, Gonzalo Arias-Gil, Manuela Marescotti, Fabio Benfenati, Bertram Gerber
Larval Drosophila offer a study case for behavioral neurogenetics that is simple enough to be experimentally tractable, yet complex enough to be worth the effort. We provide a detailed, hands-on manual for Pavlovian odor-reward learning in these animals. Given the versatility of Drosophila for genetic analyses, combined with the evolutionarily shared genetic heritage with humans, the paradigm has utility not only in behavioral neurogenetics and experimental psychology, but for translational biomedicine as well...
2017: Frontiers in Behavioral Neuroscience
https://www.readbyqxmd.com/read/28468936/solving-the-puzzle-of-neurological-diseases-an-interview-with-huda-zoghbi
#8
Huda Y Zoghbi
Huda Zoghbi's achievements in the field of neurology are internationally acclaimed. She is best known for elucidating the genetic basis of two complex neurological disorders, spinocerebellar ataxia type 1 and Rett syndrome, and has been honored with many prizes, including The Shaw Prize in Life Science and Medicine in 2016 and the 2017 Breakthrough Prize for Life Sciences. A diligent and creative research scientist at the bench, a respected lab mentor and founding Director of the Jan and Dan Duncan Neurological Research Institute at Texas Children's Hospital, her inspiration has always been the burning need to help patients faced with devastating neurological problems...
May 1, 2017: Disease Models & Mechanisms
https://www.readbyqxmd.com/read/28459648/research-microcultures-as-socialization-contexts-for-underrepresented-science-students
#9
Dustin B Thoman, Gregg A Muragishi, Jessi L Smith
How much does scientific research potentially help people? We tested whether prosocial-affordance beliefs (PABs) about science spread among group members and contribute to individual students' motivation for science. We tested this question within the context of research experience for undergraduates working in faculty-led laboratories, focusing on students who belong to underrepresented minority (URM) groups. Longitudinal survey data were collected from 522 research assistants in 41 labs at six institutions...
April 1, 2017: Psychological Science
https://www.readbyqxmd.com/read/28456446/potential-mechanisms-behind-the-antioxidant-actions-of-prolactin-in-the-retina
#10
REVIEW
Stéphanie Thébault
Causes for age-related retinal diseases are numerous and complex, and they are intertwined with the natural vision decline that accompanies aging. The elucidation of endogenous mechanisms that help maintain retinal function under conditions that are threatening for the eye and happen during natural aging is therefore critical in developing new prevention and therapeutic strategies against age-related retinal degeneration. Our lab recently reported that the hormone of lactation, prolactin, helps the retinal pigment epithelium to survive via antioxidant actions that result in the inhibition of sirtuin2-dependent cell death (EbioMedicine issue of May)...
April 26, 2017: Experimental Eye Research
https://www.readbyqxmd.com/read/28439980/nanophotonic-trapping-precise-manipulation-and-measurement-of-biomolecular-arrays
#11
REVIEW
James E Baker, Ryan P Badman, Michelle D Wang
Optical trapping is a powerful and widely used laboratory technique in the biological and materials sciences that enables rapid manipulation and measurement at the nanometer scale. However, expanding the analytical throughput of this technique beyond the serial capabilities of established single-trap microscope-based optical tweezers remains a current goal in the field. In recent years, advances in nanotechnology have been leveraged to create innovative optical trapping methods that increase the number of available optical traps and permit parallel manipulation and measurement of arrays of optically trapped targets...
April 24, 2017: Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology
https://www.readbyqxmd.com/read/28438271/how-does-an-inventor-find-an-investor-or-partner-raising-funds-to-start-a-company
#12
Rudy A Mazzocchi
Rudy Mazzocchi has over 25 years of senior executive management, technology and intellectual property development, and financing experience in the medical-technology/biotechnology industries. He serves currently as cofounder/chief executive officer of ELENZA, Inc, an ophthalmology company that has developed an electro-active, autofocusing, implantable lens; executive chairman of Establishment Labs; executive chairman of LAFORGE Optical; and executive chairman of OptiSTENT, Inc. He served previously as managing director of Accuitive Medical Ventures and The Innovation Factory; cofounder/chief executive officer of Image-Guided NEUROLOGICS, acquired by Medtronic in 2005; and founding chief executive officer of MICROVENA Corporation, which became "eV3," acquired by Covidien...
May 2017: Surgery
https://www.readbyqxmd.com/read/28435822/targeted-intracellular-heat-transfer-in-cancer-therapy-assessment-of-asparagine-laminated-gold-nanoparticles-in-cell-model-of-t-cell-leukemia
#13
Shadab Shahriari, Maryam Bakhshi, Ahmad Reza Shahverdi, Azar Berahmeh, Farnaz Safavifar, Mohammad Reza Khorramizadeh
BACKGROUND: High temperatures have destructive effects on cancer cells by damaging proteins and structures within cells. Gold nanoparticles (AuNPs) can act as drug delivery vehicles, especially for cancer therapy. Due to the selective intake of asparagine molecules into malignant cells, AuNPs were coated with asparagine; and CCRF-CEM human T-cell leukemia cells were treated with the new combination, Asn-AuNPs, at 39 °C. METHODS: The co-authors from a number of collaborative labs located at Tehran University of Medical Sciences, Tehran, Iran, have initiated the idea and preliminary design of this study in 2011...
March 2017: Iranian Journal of Public Health
https://www.readbyqxmd.com/read/28426908/clinically-useful-brain-imaging-for-neuropsychiatry-how-can-we-get-there
#14
REVIEW
Michael P Milham, R Cameron Craddock, Arno Klein
Despite decades of research, visions of transforming neuropsychiatry through the development of brain imaging-based "growth charts" or "lab tests" have remained out of reach. In recent years, there is renewed enthusiasm about the prospect of achieving clinically useful tools capable of aiding the diagnosis and management of neuropsychiatric disorders. The present work explores the basis for this enthusiasm. We assert that there is no single advance that currently has the potential to drive the field of clinical brain imaging forward...
April 20, 2017: Depression and Anxiety
https://www.readbyqxmd.com/read/28419807/otolaryngology-residency-program-research-resources-and-scholarly-productivity
#15
Jennifer A Villwock, Chelsea S Hamill, Brian D Nicholas, Jesse T Ryan
Objective To delineate research resources available to otolaryngology residents and their impact on scholarly productivity. Study Design Survey of current otolaryngology program directors. Setting Otolaryngology residency programs. Subjects and Methods An anonymous web-based survey was sent to 98 allopathic otolaryngology training program directors. Fisher exact tests and nonparametric correlations were used to determine statistically significant differences among various strata of programs. Results Thirty-nine percent (n = 38) of queried programs responded...
April 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28413632/is-in-vivo-laparoscopic-simulation-learning-a-step-forward-in-the-undergraduate-surgical-education
#16
Panteleimon Pantelidis, Michail Sideris, Georgios Tsoulfas, Efstratia-Maria Georgopoulou, Ismini Tsagkaraki, Nikolaos Staikoglou, Georgios Stagias, Nikolaos Psychalakis, Parmenion Tsitsopoulos, Thanos Athanasiou, Georgios Zografos, Apostolos Papalois
BACKGROUND: Essentials Skills in the Management of Surgical Cases - ESMSC is an International Combined Applied Surgical Science and Wet Lab course addressed at the Undergraduate level. Laparoscopic Skills is a fundamental element of Surgical Education and various Simulation-Based Learning (SBL) models have been endorsed. This study aims to explore if there is any significant difference in delegates' performance depending on whether they completed In Vivo module prior to the equivalent in the laparoscopic simulator...
April 2017: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/28407453/stressing-escherichia-coli-to-educate-students-about-research-a-cure-to-investigate-multiple-levels-of-gene-regulation
#17
Janet McDonough, Lara K Goudsouzian, Agllai Papaj, Ashley R Maceli, Vanja Klepac-Ceraj, Celeste N Peterson
Course-based undergraduate research experiences (CUREs) have been shown to increase student retention and learning in the biological sciences. Most CURES cover only one aspect of gene regulation, such as transcriptional control. Here we present a new inquiry-based lab that engages understanding of gene expression from multiple perspectives. Students carry out a forward genetic screen to identify regulators of the stationary phase master regulator RpoS in the model organism Escherichia coli and then use a series of reporter fusions to determine if the regulation is at the level of transcription or the post-transcription level...
April 13, 2017: Biochemistry and Molecular Biology Education
https://www.readbyqxmd.com/read/28365592/cell-scientist-to-watch-victoria-sanz-moreno
#18
(no author information available yet)
Vicky Sanz-Moreno received her first degree in chemistry and later a master's degree in biochemistry from the University of Oviedo in Spain, followed by a PhD in chemical sciences in the laboratory of Piero Crespo at the University of Cantabria, awarded in 2002. After a short postdoc in the same lab funded by a Lady Tata Memorial Trust Fellowship, she moved to the Institute of Cancer Research in London as a CRUK and Marie Curie Intra-European Fellow to work with Chris Marshall. In 2008, she received the Applied Biosystems and EACR 40th Anniversary Research Award...
April 1, 2017: Journal of Cell Science
https://www.readbyqxmd.com/read/28344412/clinical-and-hematobiochemical-response-in-canine-monocytic-ehrlichiosis-seropositive-dogs-of-punjab
#19
Manasa R Kottadamane, Pritpal Singh Dhaliwal, Lachhman Das Singla, Baljinder Kumar Bansal, Sanjeev Kumar Uppal
AIM: As in India especially, the Punjab state sero-prevalence and distribution of ehrlichiosis in relation to clinico-hematobiochemical response remains largely unexplored. Thus, this study was designed to determine the prevalence of vector (tick)-borne tropical canine pancytopenia caused by Ehrlichia canis through enzyme labeled ImmunoComb(®) (IC) assay in dogs from in and around Ludhiana, Punjab. Correlation of prevalence was made with various clinico-hematobiochemical parameters. MATERIALS AND METHODS: Seroprevalence study was carried out using IC(®) test kit (Biogal, Galed Labs)...
February 2017: Veterinary World
https://www.readbyqxmd.com/read/28318695/monitoring-water-quality-in-toronto-s-urban-stormwater-ponds-assessing-participation-rates-and-data-quality-of-water-sampling-by-citizen-scientists-in-the-freshwater-watch
#20
Andrew B Scott, Paul C Frost
From 2013 to 2015, citizen scientist volunteers in Toronto, Canada were trained to collect and analyze water quality in urban stormwater ponds. This volunteer sampling was part of the research program, FreshWater Watch (FWW), which aimed to standardize urban water sampling efforts from around the globe. We held training sessions for new volunteers twice yearly and trained a total of 111 volunteers. Over the course of project, ~30% of volunteers participated by collecting water quality data after the training session with 124 individual sampling events at 29 unique locations in Toronto, Canada...
March 16, 2017: Science of the Total Environment
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