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https://www.readbyqxmd.com/read/27871281/physical-multimorbidity-and-psychosis-comprehensive-cross-sectional-analysis-including-242-952-people-across-48-low-and-middle-income-countries
#1
Brendon Stubbs, Ai Koyanagi, Nicola Veronese, Davy Vancampfort, Marco Solmi, Fiona Gaughran, André F Carvalho, John Lally, Alex J Mitchell, James Mugisha, Christoph U Correll
BACKGROUND: In people with psychosis, physical comorbidities, including cardiovascular and metabolic diseases, are highly prevalent and leading contributors to the premature mortality encountered. However, little is known about physical health multimorbidity in this population or in people with subclinical psychosis and in low- and middle-income countries (LMICs). This study explores physical health multimorbidity patterns among people with psychosis or subclinical psychosis. METHODS: Overall, data from 242,952 individuals from 48 LMICs, recruited via the World Health Survey, were included in this cross-sectional study...
November 22, 2016: BMC Medicine
https://www.readbyqxmd.com/read/27760044/the-relationship-between-alexithymia-and-general-symptoms-of-pregnant-women
#2
Monavar Gilanifar, Moloud Aghajani Delavar
INTRODUCTION: Alexithymia is related to poor emotion regulation strategies as well as higher rates of somatic disorders. The aim of the present study was to assess the relationship between alexithymia and the general symptoms experienced by the pregnant women. MATERIAL AND METHODS: In a cross-sectional study, a total number of 350 pregnant women, attending the antenatal clinics, were randomly selected. A standardized Toronto Alexithymia Scale (TAS-20) was used to elicit responses from participants with alexithymia...
October 18, 2016: Romanian Journal of Internal Medicine, Revue Roumaine de Médecine Interne
https://www.readbyqxmd.com/read/27758725/-dysphagia-in-children
#3
E Ten Velde, B C Gonera-de Jong
In this case report we discuss two children with dysphagia. Both presented with difficulties in swallowing and oesophageal impaction of solid food. The first case involves a 16-year-old boy who suffered from dysphagia for many years. After a long diagnostic journey, during which a psychogenic cause was suspected, he was diagnosed with oesophageal achalasia. After a balloon dilatation of the lower oesophageal sphincter his complaints persisted and the treatment procedure was repeated. The second case involves a 15-year-old girl, who presented with a food impaction in the distal oesophagus...
2016: Nederlands Tijdschrift Voor Geneeskunde
https://www.readbyqxmd.com/read/27757131/decreased-plasma-bdnf-levels-of-patients-with-somatization-disorder
#4
Nam-In Kang, Jong-Il Park, Yong-Ku Kim, Jong-Chul Yang
OBJECTIVE: Brain-derived neurotrophic factor (BDNF), one of the most abundant and important neurotrophins, is known to be involved in the development, survival, maintenance, and plasticity of neurons in the nervous system. Some studies have suggested that BDNF may play a role in the pathophysiology of several psychiatric illnesses such as depression and schizophrenia. Similarly, it is likely that the alteration of BDNF may be associated with the neuro-modulation that contributes to the development of somatization disorder...
September 2016: Psychiatry Investigation
https://www.readbyqxmd.com/read/27660538/beyond-return-to-work-from-sickness-absence-due-to-mental-disorders-5-year-longitudinal-study-of-employment-status-among-production-workers
#5
Giny Norder, Claartje A van der Ben, Corné A M Roelen, Martijn W Heymans, Jac J L van der Klink, Ute Bültmann
BACKGROUND: Mental disorders are increasing and account for one-third of all disability benefits in OECD countries. This study investigated the work status after mental sickness absence (SA). METHODS: Five-year longitudinal cohort study of 6678 male production workers. Work status, work schedule and work hours/week were retrieved from employer records in five years following RTW from mental SA. Longitudinal analysis was done with linear and logistic generalized estimating equations estimating relative risks (RRs) and odds ratios (ORs), respectively, controlled for age, marital status and occupational grade...
September 22, 2016: European Journal of Public Health
https://www.readbyqxmd.com/read/27660201/time-of-day-dependent-adaptation-of-the-hpa-axis-to-predictable-social-defeat-stress
#6
Christiane Koch, Manuela S Bartlang, Jana Thabea Kiehn, Lisa Lucke, Nadine Naujokat, Charlotte Helfrich-Förster, Stefan O Reber, Henrik Oster
In modern societies, the risk of developing a whole array of affective and somatic disorders is associated with the prevalence of frequent psychosocial stress. Therefore, a better understanding of adaptive stress responses and their underlying molecular mechanisms is of high clinical interest. In response to an acute stressor each organism can either show passive freezing or active fight-or-flight behavior, with activation of sympathetic nervous system and the hypothalamus-pituitary-adrenal (HPA) axis providing the necessary energy for the latter by releasing catecholamines and glucocorticoids (GC)...
September 22, 2016: Journal of Endocrinology
https://www.readbyqxmd.com/read/27642179/binge-eating-disorder-in-the-swedish-national-registers-somatic-comorbidity
#7
Laura M Thornton, Hunna J Watson, Andreas Jangmo, Elisabeth Welch, Camilla Wiklund, Yvonne von Hausswolff-Juhlin, Claes Norring, Barry K Herman, Henrik Larsson, Cynthia M Bulik
OBJECTIVE: To evaluate associations between binge-eating disorder (BED) and somatic illnesses and determine whether medical comorbidities are more common in individuals who present with BED and comorbid obesity. METHOD: Cases (n = 850) were individuals with a BED diagnosis in the Swedish eating disorders quality registers. Ten community controls were matched to each case on sex, and year, month, and county of birth. Associations of BED status with neurologic, immune, respiratory, gastrointestinal, skin, musculoskeletal, genitourinary, circulatory, and endocrine system diseases were evaluated using conditional logistic regression models...
September 19, 2016: International Journal of Eating Disorders
https://www.readbyqxmd.com/read/27636931/-evaluation-of-the-therapeutic-efficacy-and-safety-of-the-selective-anxiolytic-afobazole-in-generalized-anxiety-disorder-and-adjustment-disorders-results-of-a-multicenter-randomized-comparative-study-of-diazepam
#8
T S Syunyakov, G G Neznamov
AIM: to summarize the previously published results of a multicenter randomized clinical research phase III study trial of afobazole (INN: fabomotizole) versus diazepam in the treatment of patients with generalized anxiety disorder (GAD) and adjustment disorders (AD). SUBJECTS AND METHODS: Five investigating centers included 150 patients aged 18 to 60 years (60 patients with GAD and 90 with AD) a simple structure of anxiety disorders without concurrent mental, neurological or somatic disorders...
2016: Terapevticheskiĭ Arkhiv
https://www.readbyqxmd.com/read/27635478/neuroinflammatory-genes-associated-with-post-traumatic-stress-disorder-implications-for-comorbidity
#9
Lyndon J Zass, Stephanie A Hart, Soraya Seedat, Sian M J Hemmings, Stefanie Malan-Müller
Post-traumatic stress disorder (PTSD) is a debilitating condition that only occurs in the aftermath of traumatic event exposure and is characterized by an impaired stress response and chronic, low-grade inflammation. Dysregulation of the immune system may contribute towards central nervous system tissue damage and exacerbation of fear memories following trauma. Patients with PTSD often have comorbid psychiatric and somatic disorders that are of themselves associated with heightened inflammation. Several immune-related genes have been associated with PTSD and other co-occurring disorders...
September 15, 2016: Psychiatric Genetics
https://www.readbyqxmd.com/read/27580599/-health-related-long-term-effects-of-adverse-childhood-experiences-an-update
#10
Ulrich T Egle, Matthias Franz, Peter Joraschky, Astrid Lampe, Inge Seiffge-Krenke, Manfred Cierpka
In the last decade strong empirical evidence from several long-term studies supports the conclusion that physical and sexual abuse as well as emotional deprivation in childhood make people significantly more vulnerable to mental and functional disorders across their lifetime. Additionally, an increased vulnerability to several somatic disorders (cardiovascular disorders, type-2-diabetes, hepatitis, chronic obstructive pulmonary disease (COPD), immunological and pain disorders, pharynx and lung cancer) was demonstrated - most of them with a reduced life expectancy...
October 2016: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/27503108/association-of-affective-temperaments-with-blood-pressure-and-arterial-stiffness-in-hypertensive-patients-a-cross-sectional-study
#11
Andrea László, Ádám Tabák, Beáta Kőrösi, Dániel Eörsi, Péter Torzsa, Orsolya Cseprekál, András Tislér, György Reusz, Zsófia Nemcsik-Bencze, Xénia Gonda, Zoltán Rihmer, János Nemcsik
BACKGROUND: Affective temperaments (anxious, depressive, cyclothymic, irritable and hyperthymic) measure subclinical manifestations of major mood disorders. Furthermore, cumulating evidence suggests their involvement in somatic disorders as well. We aimed to assess associations between affective temperament scores and blood pressure and arterial stiffness parameters in hypertensive patients. METHODS: In this cross-sectional study, 173 patients with well-controlled or grade 1 chronic hypertension, with no history of depression, completed the TEMPS-A, Beck Depression Inventory (BDI) and Hamilton Anxiety Scale (HAM-A) questionnaires in three GP practices...
2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27487529/-life-satisfaction-and-self-esteem-among-women-in-the-menopausal-time
#12
Zbigniew Banaczek, Agnieszka Saracen
INTRODUCTION: The period of menopause is usually a long-lasting, running process, with strong hormone changes which are manifested with somatic disorders and the lability of the emotional state. The degree of severity of the occurence of these symptoms can be variously bolstered. These changes can affect the quality of life and ones self-esteem. THE AIM: To assess the level of self-esteem of biopsychosocial functioning women in the menopausal time and the impact of menopause on women's quality of life...
2016: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/27487406/the-effects-of-oscillatory-biofield-therapy-on-pain-and-functional-limitations-associated-with-carpal-tunnel-syndrome-randomized-placebo-controlled-double-blind-study
#13
Mohammad Reza Nourbakhsh, Thomas J Bell, Jason Benson Martin, Amir Massoud Arab
OBJECTIVES: Biofield treatments have been used for pain control in patients with cancer and chronic pain. However, research on the effect of biofield treatment on specific somatic disorders is lacking. This study intends to investigate the effect of oscillating biofield therapy (OBFT) on symptoms of carpal tunnel syndrome. DESIGN: Randomized, placebo-controlled, double-blind study. PARTICIPANTS: Thirty patients with chronic carpal tunnel syndrome participated in the study...
November 2016: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
https://www.readbyqxmd.com/read/27474691/-capacity-impairments-and-participation-restrictions-assessment-and-qualifying-in-the-sociomedical-evaluation-of-mental-disorders
#14
Michael Linden
Participation is defined, according to the International Classification of Functioning, Disability and Health (ICF), as inclusion in life. Participation restrictions are the result of a mismatch between capacities and context requirements. Mental disorders are more impairing than many somatic disorders.There are instruments to assess and operationalize capacity and participation restrictions like the ADL-scales, the GAF, the ICF-AT-50, the ICFPsych A&P, the IMET, the ICF-Coresets, the WHODAS, or the Mini-ICF-APP, which differ in respect to indications, differentiation between function, capacity or context and context-adjusted qualifying...
September 2016: Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz
https://www.readbyqxmd.com/read/27429167/shall-we-really-say-goodbye-to-first-rank-symptoms
#15
A Heinz, M Voss, S M Lawrie, A Mishara, M Bauer, J Gallinat, G Juckel, U Lang, M Rapp, P Falkai, W Strik, J Krystal, A Abi-Dargham, S Galderisi
BACKGROUND: First rank symptoms (FRS) of schizophrenia have been used for decades for diagnostic purposes. In the new version of the DSM-5, the American Psychiatric Association (APA) has abolished any further reference to FRS of schizophrenia and treats them like any other "criterion A" symptom (e.g. any kind of hallucination or delusion) with regard to their diagnostic implication. The ICD-10 is currently under revision and may follow suit. In this review, we discuss central points of criticism that are directed against the continuous use of first rank symptoms (FRS) to diagnose schizophrenia...
September 2016: European Psychiatry: the Journal of the Association of European Psychiatrists
https://www.readbyqxmd.com/read/27428190/clinical-significance-of-increased-cerebellar-default-mode-network-connectivity-in-resting-state-patients-with-drug-naive-somatization-disorder
#16
Houliang Wang, Wenbin Guo, Feng Liu, Jindong Chen, Renrong Wu, Zhikun Zhang, Miaoyu Yu, Lehua Li, Jingping Zhao
The cerebellum has been proven to be connected to the brain network, as in the default-mode network (DMN), among healthy subjects and patients with psychiatric disorders. However, whether or not abnormal cerebellar DMN connectivity exists and what its clinical significance is among drug-naive patients with somatization disorder (SD) at rest remain unclear.A total of 25 drug-naive patients with SD and 28 healthy controls were enrolled for a resting-state scan. The imaging data were analyzed using the seed-based functional connectivity (FC) method...
July 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27421707/electronic-support-groups-an-open-line-of-communication-in-contested-illness
#17
Michael Murphy, Nicholas Kontos, Oliver Freudenreich
BACKGROUND: Patients with functional somatic syndromes are often difficult to treat. The relationship between doctors and patients can be strained, which limits communication. Instead, patients often communicate with each other over the Internet in electronic support groups. OBJECTIVE: This perspective summarizes studies of patient-to-patient communication over the Internet and uses the concept of contested illness to provide insights into the experiences of patients with functional somatic disorders...
April 29, 2016: Psychosomatics
https://www.readbyqxmd.com/read/27402529/hydrogen-peroxide-induced-oxidative-damage-in-peripheral-blood-lymphocytes-from-rats-chronically-treated-with-corticosterone-the-protective-effect-of-oxytocin-treatment
#18
Dušanka Stanić, Bosiljka Plećaš-Solarović, Jelena Petrović, Nataša Bogavac-Stanojević, Miron Sopić, Jelena Kotur-Stevuljević, Svetlana Ignjatović, Vesna Pešić
Contemporary lifestyle is commonly associated with chronic stress, an environmental factor contributing to development of various psychological and somatic disorders. Increased levels of glucocorticoids, observed in the chronic stress, induce the production of reactive oxygen species leading to genotoxicity. The aim of this study was to investigate whether chronic administration of oxytocin (OXY) 10 IU/400 μL/day, s.c., for 14 days, a hormone presumed to exert antioxidant effect, may prevent DNA damage in the comet assay of peripheral blood lymphocytes of Wistar rats treated chronically with corticosterone (CORT) 100 mg/L ad libitum, per os, for 21 days, as well as, to influence some plasma oxidative stress parameters, i...
August 25, 2016: Chemico-biological Interactions
https://www.readbyqxmd.com/read/27348169/dynamics-of-opioid-substitution-treatmentin-different-initial-substance-user-opioid-dependent-patients
#19
Kh Todadze, S Mosia
Injecting drug user size estimation studies carried out in 2009, 2012 and 2015 revealed growing trends of drug abuse in Georgia:estimated number of people who inject drugs (PWID) have been increased from 40000 and 45000 to 50000. Since Soviet period the most popular injective narcotics have been opioids: home-made opium, heroine, buprenorphine and home-made desomorphine ("Krokodile") replacing each other on the black market. Self-made desomorphine typically contains big amounts of different toxic substances and causes significant somatic disorders, especially skin, bone, blood infections, liver and kidney failure; is highly addictive, associates with frequent injections that enhance injecting-related harm, including the risk of HIV transmission, in comparison with typical opioids...
May 2016: Georgian Medical News
https://www.readbyqxmd.com/read/27334010/relationship-between-anxiety-level-and-radiological-investigation-comparison-among-different-diagnostic-imaging-exams-in-a-prospective-single-center-study
#20
Giuseppe Lo Re, Rossella De Luca, Filippa Muscarneri, Patrizia Dorangricchia, Dario Picone, Federica Vernuccio, Sergio Salerno, Giuseppe La Tona, Antonio Pinto, Massimo Midiri, Antonio Russo, Roberto Lagalla, Giuseppe Cicero
OBJECTIVE: Every patient could feel anxious when he waits in a radiological department to undergo diagnostic exams. The aim of our study is to evaluate the impact of the radiological exams on patient anxiety. MATERIALS AND METHODS: We evaluated 343 patients (mean age 54.83 years) who underwent different types of diagnostic exams in the Department of Diagnostic Imaging at our Hospital from April 2013 to August 2014. We administered to patients the State and Trait Anxiety Inventory Test, which detected with high sensitivity both state anxiety and trait anxiety...
October 2016: La Radiologia Medica
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