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https://www.readbyqxmd.com/read/29792576/using-a-deep-learning-network-to-recognize-low-back-pain-in-static-standing
#1
Boyi Hu, Chong Kim, Xiaopeng Ning, Xu Xu
Low back pain remains one of the most prevalent musculoskeletal disorders, while algorithms that able to recognize low back pain patients from healthy population using balance performance data are rarely seen. In this study, human balance and body sway performance during standing trials were utilized to recognize chronic low back pain populations using deep neural networks. To be specific, forty-four chronic LBP and healthy individuals performed static standing tasks while their spine kinematics and center of pressure were recorded...
May 24, 2018: Ergonomics
https://www.readbyqxmd.com/read/29784246/the-effect-of-a-maternity-support-belt-on-static-stability-and-posture-in-pregnant-and-non-pregnant-women
#2
Marie Elena Bey, Adamantios Arampatzis, Kirsten Legerlotz
PURPOSE: Physical and hormonal changes during pregnancy are thought to affect balance and injury risk, with increased numbers of falls being reported. A maternity support belt (MSB) has been suggested to stabilize the pelvis and to enhance balance. The purpose of this study was therefore to investigate the effect of an MSB on postural stability in different trimesters of pregnancy. METHODS: Postural stability was assessed in the first (T1, n = 30), second (T2, n = 30) and third trimester (T3, n = 30) of pregnancy and compared to non-pregnant controls (n = 30), using a portable force plate...
May 18, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29778979/exploring-the-relationship-between-stability-and-variability-of-the-centre-of-mass-and-centre-of-pressure
#3
Roshanth Rajachandrakumar, Jotvarinder Mann, Alison Schinkel-Ivy, Avril Mansfield
BACKGROUND: There are competing perspectives in the literature regarding the role of movement variability in quiet standing and balance control. Some view high variability as indicative of poor balance control and a contributor to increased fall risk, whereas others view variability as beneficial in providing sensory information that aids balance control. RESEARCH QUESTION: This study aimed to help to clarify the role of variability in balance control by testing two competing hypotheses: that increased variability would lead to instability, or that increased variability would improve stability, where stability is defined as the ability to respond to a perturbation...
May 9, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29777133/selective-improvements-in-balancing-associated-with-offline-periods-of-spaced-training
#4
Antonino Casabona, Maria Stella Valle, Carlo Cavallaro, Gabriele Castorina, Matteo Cioni
Benefits from post-training memory processing have been observed in learning many procedural skills. Here, we show that appropriate offline periods produce a performance gain during learning to stand on a multiaxial balance board. The tilt angle and the area of sway motion of the board were much more reduced in participants performing a training spaced by an interval of one day with respect to participants executing the same amount of practice over a concentrated period. In particular, offline memory encoding was specifically associated with the motion along the anterior-posterior direction, the spatio-temporal dynamics, and the frequency contents of the board sway...
May 18, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29775954/a-new-methodology-based-on-functional-principal-component-analysis-to-study-postural-stability-post-stroke
#5
M Luz Sánchez-Sánchez, Juan-Manuel Belda-Lois, Silvia Mena-Del Horno, Enrique Viosca-Herrero, Celedonia Igual-Camacho, Beatriz Gisbert-Morant
BACKGROUND: A major goal in stroke rehabilitation is the establishment of more effective physical therapy techniques to recover postural stability. Functional Principal Component Analysis provides greater insight into recovery trends. However, when missing values exist, obtaining functional data presents some difficulties. The purpose of this study was to reveal an alternative technique for obtaining the Functional Principal Components without requiring the conversion to functional data beforehand and to investigate this methodology to determine the effect of specific physical therapy techniques in balance recovery trends in elderly subjects with hemiplegia post-stroke...
May 5, 2018: Clinical Biomechanics
https://www.readbyqxmd.com/read/29772496/vibrotactile-feedback-alters-dynamics-of-static-postural-control-in-persons-with-parkinson-s-disease-but-not-older-adults-at-high-fall-risk
#6
Carleigh M High, Hannah F McHugh, Stephen C Mills, Shinichi Amano, Jane E Freund, Srikant Vallabhajosula
BACKGROUND: Aging and Parkinson's disease are often associated with impaired postural control. Providing extrinsic feedback via vibrotactile sensation could supplement intrinsic feedback to maintain postural control. RESEARCH QUESTION: We investigated the postural control response to vibrotactile feedback provided at the trunk during challenging stance conditions in older adults at high fall risk and individuals with Parkinson's disease compared to healthy older adults...
May 8, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29770123/what-if-low-back-pain-is-the-most-prevalent-parkinsonism-in-the-world
#7
Jesse V Jacobs, Sharon M Henry, Fay B Horak
Low back pain (LBP) has a point prevalence of nearly 10% and ranks highest in global disease burden for years lived with disability; Parkinson's disease (PD) ranks in the top 100 most disabling health conditions for years lost and years lived with disability (1). Recent evidence suggests that people with chronic, recurrent LBP exhibit many postural impairments reminiscent of a neurological postural disorder such as PD. We compare and contrast postural impairments associated with LBP and PD in order to inform treatment strategies for both conditions...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29769108/correlation-between-the-sagittal-spinopelvic-alignment-and-degenerative-lumbar-spondylolisthesis-a-retrospective-study
#8
Qi Lai, Tian Gao, Xin Lv, Xuqiang Liu, Zongmiao Wan, Min Dai, Bin Zhang, Tao Nie
BACKGROUND: Pain and disability associated with degenerative lumbar spondylolisthesis (DLS) results in significant burden on both the patients' quality of life and healthcare costs. Currently, there is controversy regarding the specificity of spinopelvic measures of sagittal plane alignment with respect to DLS. Moreover, the correlation among spinopelvic parameters of sagittal plane alignment remains to be clarified. Our aim in this study was to compare these measurements between patients with single-segment DLS at L5 and a control group with no history of DLS...
May 16, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29769023/risk-factors-for-incident-falls-in-older-men-and-women-the-english-longitudinal-study-of-ageing
#9
Catharine R Gale, Leo D Westbury, Cyrus Cooper, Elaine M Dennison
BACKGROUND: Falls are a major cause of disability and death in older people, particularly women. Cross-sectional surveys suggest that some risk factors associated with a history of falls may be sex-specific, but whether risk factors for incident falls differ between the sexes is unclear. We investigated whether risk factors for incident falls differ between men and women. METHODS: Participants were 3298 people aged ≥60 who took part in the Waves 4-6 surveys of the English Longitudinal Study of Ageing...
May 16, 2018: BMC Geriatrics
https://www.readbyqxmd.com/read/29768008/striking-a-balance-between-carbonate-carbamate-linkage-bond-and-reduction-sensitive-disulfide-bond-bearing-linker-for-tailored-controlled-release-in-situ-covalently-albumin-binding-gemcitabine-prodrugs-promote-bioavailability-and-tumor-accumulation
#10
Huicong Zhang, Kuanglei Wang, Kexin Na, Dan Li, Zhenbao Li, Dongyang Zhao, Lu Zhong, Menglin Wang, Longfa Kou, Cong Luo, Haotian Zhang, Qiming Kan, Huaiwei Ding, Zhonggui He, Jin Sun
To address the challenge of rapid enzyme inactivation, poor tumor targeting, acquired drug resistance in gemcitabine (GEM) application, we report two groups of maleimide-functionalised GEM prodrugs conjugating covalently in situ with cys-34 of blood-circulating albumin, resulting in macromolecular prodrugs after intravenous administration. Specially, tailored and accurate controlled release was achieved through different combinations of linkage bonds relatively stable and labile (carbamate and carbonate, respectively) and linkers with or without insertion of a disulfide bond...
May 16, 2018: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29767651/impaired-standing-balance-in-individuals-with-cervicogenic-headache-and-migraine
#11
Munlika Sremakaew, Somporn Sungkarat, Julia Treleaven, Sureeporn Uthaikhup
AIMS: To determine whether a difference in standing balance exists among individuals with cervicogenic headache, those with migraine, and asymptomatic controls. METHODS: A total of 24 participants with cervicogenic headache, 24 with migraine, and 24 asymptomatic controls of similar age, gender, and body mass index were included. Standing balance was assessed with a swaymeter under the conditions of eyes open and closed; on firm and soft surfaces; and in comfortable and narrow stances (for a total of eight testing conditions)...
May 15, 2018: Journal of Oral & Facial Pain and Headache
https://www.readbyqxmd.com/read/29767354/proprioceptive-muscle-tendon-stimulation-reduces-symptoms-in-primary-orthostatic-tremor
#12
M Wuehr, C Schlick, K Möhwald, R Schniepp
INTRODUCTION: Primary orthostatic tremor (OT) is characterized by high-frequency lower limb muscle contractions and a disabling sense of unsteadiness while standing. To date, therapeutic options for OT are limited. Here, we examined the effects of proprioceptive leg muscle stimulation via muscle tendon vibration (MTV) on tremor and balance control in patients with primary OT. METHODS: Tremor in nine patients with primary OT was examined during four conditions: standing (1), standing with MTV on the bilateral soleus muscles (2), lying (3), and lying with MTV (4)...
May 16, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29765005/heart-rate-recovery-physical-activity-level-and-functional-status-in-subjects-with-copd
#13
Andrea A Morita, Laís K O Silva, Gianna W Bisca, Joice M Oliveira, Nidia A Hernandes, Fabio Pitta, Karina C Furlanetto
BACKGROUND: A normal heart rate reflects the balance between the sympathetic and parasympathetic autonomic nervous system. When the difference between heart rate at the end of an exercise test and after 1 min of recovery, known as the 1-min heart rate recovery, is ≤ 12 beats/min, this may indicate an abnormal delay. We sought to compare physical activity patterns and subjects' functional status with COPD with or without delayed 1-min heart rate recovery after the 6-min walk test (6MWT)...
May 15, 2018: Respiratory Care
https://www.readbyqxmd.com/read/29764619/effects-of-unexpected-visual-motion-on-postural-sway-and-motion-sickness
#14
Mark Dennison, Michael D'Zmura
Motion sickness is thought to occur when the brain's assumptions about incoming sensory information do not match the actual signals received. These signals must involve the vestibular system for motion sickness to occur. In this paper, we describe an experiment in which subjects experienced unexpected visual motions, or perturbations, as they navigated a virtual environment (VE) while standing and wearing a head mounted display (HMD) or while viewing a monitor. We found that postural instability, as measured by a balance board, increased with time only when perturbations were present...
September 2018: Applied Ergonomics
https://www.readbyqxmd.com/read/29763813/age-and-gymnastic-experience-effects-on-sensory-reweighting-processes-during-quiet-stand
#15
Albert Busquets, Silvia Aranda-Garcia, Blai Ferrer-Uris, Michel Marina, Rosa Angulo-Barroso
BACKGROUND: The relative contribution of sensory inputs to control balance while standing is dynamically adjusted. These sensory reweighting processes could be impacted by age and sport expertise capabilities, especially when the sport emphasizes equilibrium like artistic gymnastics. RESEARCH QUESTION: The aim of this study was to explore the sensory reweighting processes to adjust standing posture in children and adults with different gymnastic expertise (gymnasts, G, and non-gymnast, NG)...
May 8, 2018: Gait & Posture
https://www.readbyqxmd.com/read/29763676/effect-of-single-session-dual-tdcs-before-physical-therapy-on-lower-limb-performance-in-sub-acute-stroke-patients-a-randomized-sham-controlled-crossover-study
#16
Wanalee Klomjai, Benchaporn Aneksan, Anuchai Pheungphrarattanatrai, Thanwarat Chantanachai, Nattha Choowong, Soontaree Bunleukhet, Paradee Auervitchayapat, Yongchai Nilanon, Vimonwan Hiengkaew
Anodal stimulation increases cortical excitably, whereas cathodal stimulation decreases cortical excitability. Dual transcranial direct current stimulation (tDCS; anodal over the lesioned hemisphere, cathodal over the non-lesioned hemisphere) was found to enhance motor learning. The corresponding tDCS-induced changes were reported to reduce the inhibition exerted by the unaffected hemisphere on the affected hemisphere and restore the normal balance of the interhemispheric inhibition. Most studies were devoted to the possible modification of upper-limb motor function after tDCS; however, almost no study has demonstrated its effects on lower-limb function and gait, which are also commonly disordered in stroke patients with motor deficits...
May 12, 2018: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/29761295/a-startling-acoustic-stimulus-facilitates-voluntary-lower-extremity-movements-and-automatic-postural-responses-in-people-with-chronic-stroke
#17
Milou J M Coppens, Jolanda M B Roelofs, Nicole A J Donkers, Jorik Nonnekes, Alexander C H Geurts, Vivian Weerdesteyn
A startling acoustic stimulus (SAS) involuntary releases prepared movements at accelerated latencies, known as the StartReact effect. Previous work has demonstrated intact StartReact in paretic upper extremity movements in people after stroke, suggesting preserved motor preparation. The question remains whether motor preparation of lower extremity movements is also unaffected after stroke. Here, we investigated StartReact effects on ballistic lower extremity movements and on automatic postural responses (APRs) following perturbations to standing balance...
May 14, 2018: Journal of Neurology
https://www.readbyqxmd.com/read/29758971/effects-of-dancesport-on-walking-balance-and-standing-balance-among-the-elderly
#18
Jeehoon Sohn, Sung-Ha Park, Sukwon Kim
BACKGROUND: Dancesport is a popular activity among older adults who look for fun and fitness in Korea. Studies reported positive sociological and psychological effects of dancesport. But, little studies were performed to evaluate the effects of dancesport on balance performances. OBJECTIVE: The objective of the present study was to evaluate the effects of dancesport for 15 weeks on walking balance and standing balance of older adults. METHODS: Older adults regularly participated in the dancesport program 3 times a week for 15 weeks...
May 4, 2018: Technology and Health Care: Official Journal of the European Society for Engineering and Medicine
https://www.readbyqxmd.com/read/29746803/urine-specific-gravity-as-an-indicator-of-dehydration-in-olympic-combat-sport-athletes-considerations-for-research-and-practice
#19
Damir Zubac, Reid Reale, Hrvoje Karnincic, Anamaria Sivric, Igor Jelaska
Urine specific gravity (USG ) is the most commonly reported biochemical marker used in research and applied settings to detect fluid deficits in athletes, including those participating in combat sports. Despite the popularity of its use, there has been a growing debate regarding the diagnostic accuracy and the applicability of USG in characterizing whole-body fluid status and fluctuations. Moreover, recent investigations report universally high prevalence of hypohydration (∼90%) via USG assessment in combat sport athletes, often in spite of stable body-mass...
May 10, 2018: European Journal of Sport Science
https://www.readbyqxmd.com/read/29743368/stat2-dependent-immune-responses-ensure-host-survival-despite-the-presence-of-a-potent-viral-antagonist
#20
Vu Thuy Khanh Le-Trilling, Kerstin Wohlgemuth, Meike U Rückborn, Andreja Jagnjic, Fabienne Maaßen, Lejla Timmer, Benjamin Katschinski, Mirko Trilling
Pathogen encounter induces interferons which signal via Janus kinases and STAT transcription factors to establish an antiviral state. However, host and pathogens are situated in a continuous arms race which shapes host evolution towards optimized immune responses and the pathogens towards enhanced immune evasive properties.Mouse cytomegalovirus (MCMV) counteracts interferon responses by pM27-mediated degradation of STAT2 which directly affects the signaling of type I as well as type III interferons. Using MCMV mutants lacking M27 and mice lacking STAT2, we studied the opposing relationship between antiviral activities and viral antagonism in a natural host-pathogen pair in vitro and in vivo In contrast to wt-MCMV, ΔM27-MCMV was efficiently cleared from all organs within a few days in BALB/c, C57BL/6, and 129 mice, highlighting the general importance of STAT2 antagonism for MCMV replication...
May 9, 2018: Journal of Virology
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