A Szóstek-Mioduchowska, A Wójtowicz, A Sadowska, B Moza Jalali, M Słyszewska, K Łukasik, A Gurgul, T Szmatoła, M Bugno-Poniewierska, G Ferreira-Dias, D J Skarzynski
In the current study, transcriptome profiles of mare endometrium, classified into categories I, IIA, and IIB according to Kenney and Doig, were compared using RNA sequencing, analyzed, and functionally annotated using in silico analysis. In the mild stage (IIA) of endometrosis compared to category I endometrium, differentially expressed genes (DEGs) were annotated to inflammation, abnormal metabolism, wound healing, and quantity of connective tissue. In the moderate stage (IIB) of endometrosis compared to category I endometrium, DEGs were annotated to inflammation, fibrosis, cellular homeostasis, mitochondrial dysfunction, and pregnancy disorders...
September 27, 2023: Scientific Reports