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https://www.readbyqxmd.com/read/29350143/adenovirus-type-4-respiratory-infections-among-civilian-adults-northeastern-united-states-2011-20151
#1
Adriana E Kajon, Daryl M Lamson, Camden R Bair, Xiaoyan Lu, Marie L Landry, Marilyn Menegus, Dean D Erdman, Kirsten St George
Human adenovirus type 4 (HAdV-4) is most commonly isolated in military settings. We conducted detailed molecular characterization on 36 HAdV-4 isolates recovered from civilian adults with acute respiratory disease (ARD) in the northeastern United States during 2011-2015. Specimens came from college students, residents of long-term care facilities or nursing homes, a cancer patient, and young adults without co-morbidities. HAdV-4 genome types 4a1 and 4a2, the variants most frequently detected among US military recruits in basic training before the restoration of vaccination protocols, were isolated in most cases...
February 2018: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/29314843/multipolar-nanocube-plasmon-mode-mixing-in-finite-substrates
#2
Charles Cherqui, Guoliang Li, Jacob A Busche, Steven C Quillin, Jon P Camden, David J Masiello
Facile control of the radiative and nonradiative properties of plasmonic nanostructures is of practical importance to a wide range of applications in the biological, chemical, optical, information, and energy sciences. For example, the ability to easily tune not only the plasmon spectrum but also the degree of coupling to light and/or heat, quality factor, and optical mode volume would aid the performance and function of nanophotonic devices and molecular sensors that rely upon plasmonic elements to confine and manipulate light at nanoscopic dimension...
January 9, 2018: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29297959/p2y2-r-deletion-ameliorates-sialadenitis-in-il-14%C3%AE-transgenic-mice
#3
Lucas T Woods, Jean M Camden, Mahmoud G Khalafalla, Michael J Petris, Laurie Erb, Julian L Ambrus, Gary A Weisman
OBJECTIVE: Interleukin-14α-transgenic (IL-14αTG) mice develop an autoimmune exocrinopathy with characteristics similar to Sjögren's syndrome, including sialadenitis and hyposalivation. The P2Y2 receptor (P2Y2 R) for extracellular ATP and UTP is upregulated during salivary gland inflammation (i.e., sialadenitis) where it regulates numerous inflammatory responses. The present study investigated the role of P2Y2 Rs in autoimmune sialadenitis in the IL-14αTG mouse model of Sjögren's syndrome...
January 3, 2018: Oral Diseases
https://www.readbyqxmd.com/read/29260923/exploring-engagement-in-a-virtual-community-of-practice-in-pediatric-rehabilitation-who-are-non-users-lurkers-and-posters
#4
Karen Hurtubise, Gabrielle Pratte, Lisa Rivard, Jade Berbari, Léa Héguy, Chantal Camden
PURPOSE: Communities of practice are increasingly recognized in rehabilitation as useful knowledge transfer tools; however, little is known about their users. This exploratory study describes the characteristics of participants and non-participants invited to engage in a pediatric rehabilitation virtual community of practice. In addition, we explored virtual community of practice utilization behaviors, engagement predictors, and the impact of strategies designed to foster engagement. MATERIALS AND METHODS: Participants' demographics including information-seeking style and organization e-readiness, as well as online platform frequency of use data were collected and analyzed using descriptive, comparative, and predictive statistics...
December 20, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/29247095/effectiveness-and-cost-effectiveness-of-implementing-hiv-testing-in-primary-care-in-east-london-protocol-for-an-interrupted-time-series-analysis
#5
Werner Leber, Lee Beresford, Claire Nightingale, Estela Capelas Barbosa, Stephen Morris, Farah El-Shogri, Heather McMullen, Kambiz Boomla, Valerie Delpech, Alison Brown, Jane Hutchinson, Vanessa Apea, Merle Symonds, Samantha Gilliham, Sarah Creighton, Maryam Shahmanesh, Naomi Fulop, Claudia Estcourt, Jane Anderson, Jose Figueroa, Chris Griffiths
INTRODUCTION: HIV remains underdiagnosed. Guidelines recommend routine HIV testing in primary care, but evidence on implementing testing is lacking. In a previous study, the Rapid HIV Assessment 2 (RHIVA2) cluster randomised controlled trial, we showed that providing training and rapid point-of-care HIV testing at general practice registration (RHIVA2 intervention) in Hackney led to cost-effective, increased and earlier diagnosis of HIV. However, interventions effective in a trial context may be less so when implemented in routine practice...
December 14, 2017: BMJ Open
https://www.readbyqxmd.com/read/29215265/probing-nanoparticle-plasmons-with-electron-energy-loss-spectroscopy
#6
Yueying Wu, Guoliang Li, Jon P Camden
Electron energy loss spectroscopy (EELS) performed in a scanning transmission electron microscope (STEM) has demonstrated unprecedented power in the characterization of surface plasmons. The subangstrom spatial resolution achieved in EELS and its capability of exciting the full set of localized surface plasmon resonance (LSPR) modes supported by a metallic nanostructure makes STEM/EELS an ideal tool in the study of LSPRs. The plasmonic properties characterized using EELS can be associated with geometric or structural features collected simultaneously in a STEM to achieve a deeper understanding of the plasmonic response...
December 7, 2017: Chemical Reviews
https://www.readbyqxmd.com/read/29204525/sbrt-to-adrenal-metastases-provides-high-local-control-with-minimal-toxicity
#7
Kristin Plichta, Nathan Camden, Muhammed Furqan, Taher Abu Hejleh, Gerald H Clamon, Jun Zhang, Ryan T Flynn, Sudershan K Bhatia, Mark C Smith, John M Buatti, Bryan G Allen
Purpose: The adrenal glands are a common site of metastases because of their rich blood supply. Previously, adrenal metastases were treated with systemic chemotherapy or, more rarely, with surgical resection or palliative radiation therapy. Stereotactic body radiation therapy (SBRT) has recently emerged as an attractive noninvasive approach to definitively treat these lesions. We present our experience in treating adrenal metastases using SBRT and review the current literature. Methods and materials: This is a single-institution retrospective review of patients who received SBRT to adrenal metastases originating from various primary malignancies...
October 2017: Advances in Radiation Oncology
https://www.readbyqxmd.com/read/29181865/a-%C3%AF-conjugation-extended-viologen-as-novel-two-electron-storage-anolyte-for-total-organic-aqueous-redox-flow-battery
#8
Jian Luo, Bo Hu, Camden Debruler, Tianbiao Leo Liu
Extending the conjugation of viologen by a planar thiazolo[5,4-d]thiazole (TTz) framework and functionalizing the pyridinium with hydrophilic ammonium group yielded a highly water-soluble "π-conjugation extended viologen", 4,4'-(thiazolo[5,4-d]thiazole-2,5-diyl)bis(1-(3-(trimethylammonio)propyl)pyridin-1-ium) tetrachloride, [(NPr)2TTz]Cl4, as a novel two-electron storage anolyte for AORFB applications. Its physical and electrochemical properties were systematically investigated. The [(NPr)2TTz]Cl4 / NMe-TEMPO AORFB enables a 1...
November 27, 2017: Angewandte Chemie
https://www.readbyqxmd.com/read/29161521/lessons-from-the-camden-coalition-of-healthcare-providers-first-medicaid-shared-savings-performance-evaluation
#9
Aaron Truchil, Natasha Dravid, Stephen Singer, Zachary Martinez, Teagan Kuruna, Scott Waulters
Accountable Care Organizations (ACOs) aim to reduce health care costs while improving patient outcomes. Camden Coalition of Healthcare Providers' (Camden Coalition) work already aligned with this aim before receiving state approval to operate a certified Medicaid ACO in New Jersey. Upon its formation, the Camden Coalition ACO partnered with UnitedHealthcare and, through state legislation, Rutgers Center for State Health Policy (CSHP) was established as its external evaluator. In evaluating the Camden Coalition ACO, Rutgers CSHP built on the Medicare Shared Savings model, but modified it based on the understanding that the Medicaid population differs from the Medicare population...
November 21, 2017: Population Health Management
https://www.readbyqxmd.com/read/29161308/effects-of-tones-associated-with-drilling-activities-on-bowhead-whale-calling-rates
#10
Susanna B Blackwell, Christopher S Nations, Aaron M Thode, Mandy E Kauffman, Alexander S Conrad, Robert G Norman, Katherine H Kim
During summer 2012 Shell performed exploratory drilling at Sivulliq, a lease holding located in the autumn migration corridor of bowhead whales (Balaena mysticetus), northwest of Camden Bay in the Beaufort Sea. The drilling operation involved a number of vessels performing various activities, such as towing the drill rig, anchor handling, and drilling. Acoustic data were collected with six arrays of directional recorders (DASARs) deployed on the seafloor over ~7 weeks in Aug-Oct. Whale calls produced within 2 km of each DASAR were identified and localized using triangulation...
2017: PloS One
https://www.readbyqxmd.com/read/29128988/employing-community-voices-informing-practice-and-programming-through-camden-healthy-start-focus-groups
#11
Dianne R Browne, Sherolde Hackett, Allison Burger
Objectives Women living in communities with low-socioeconomic status, substandard healthcare, and ongoing exposure to social disparities encounter barriers to healthcare, often making it difficult to access health services. Barriers may stem from provider interactions with clients, conditions of the healthcare facility, or even language barriers. This prompts a call for providers to be keenly aware of the obstacles women encounter when attempting to access services. Methods In an effort to facilitate better access to services, Camden Healthy Start conducted six focus groups...
November 11, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29079602/randomised-controlled-trial-of-the-clinical-and-cost-effectiveness-of-a-peer-delivered-self-management-intervention-to-prevent-relapse-in-crisis-resolution-team-users-study-protocol
#12
Sonia Johnson, Oliver Mason, David Osborn, Alyssa Milton, Claire Henderson, Louise Marston, Gareth Ambler, Rachael Hunter, Stephen Pilling, Nicola Morant, Richard Gray, Tim Weaver, Fiona Nolan, Brynmor Lloyd-Evans
INTRODUCTION: Crisis resolution teams (CRTs) provide assessment and intensive home treatment in a crisis, aiming to offer an alternative for people who would otherwise require a psychiatric inpatient admission. They are available in most areas in England. Despite some evidence for their clinical and cost-effectiveness, recurrent concerns are expressed regarding discontinuity with other services and lack of focus on preventing future relapse and readmission to acute care. Currently evidence on how to prevent readmissions to acute care is limited...
October 27, 2017: BMJ Open
https://www.readbyqxmd.com/read/28989621/utilizing-light-triggered-plasmon-driven-catalysis-reactions-as-a-template-for-molecular-delivery-and-release
#13
Xin Gu, Huan Wang, Jon P Camden
Due to the facile manipulation and non-invasive nature of light-triggered release, it is one of the most potent ways to selectively and remotely deliver a molecular target. Among the various carrier platforms, plasmonic nanoparticles possess advantages such as enhanced cellular uptake and easy loading of "cargo" molecules. Two general strategies are currently utilized to achieve light-induced molecule release from plasmonic nanoparticles. The first uses femtosecond laser pulses to directly break the bond between the nanoparticle and the loaded target...
September 1, 2017: Chemical Science
https://www.readbyqxmd.com/read/28911214/growth-regulation-by-estrogen-in-breast-cancer-1-greb1-is-a-novel-progesterone-responsive-gene-required-for-human-endometrial-stromal-decidualization
#14
Alison J Camden, Maria M Szwarc, Sangappa B Chadchan, Francesco J DeMayo, Bert W O'Malley, John P Lydon, Ramakrishna Kommagani
STUDY QUESTION: Is Growth Regulation by Estrogen in Breast Cancer 1 (GREB1) required for progesterone-driven endometrial stromal cell decidualization? SUMMARY ANSWER: GREB1 is a novel progesterone-responsive gene required for progesterone-driven human endometrial stromal cell (HESC) decidualization. WHAT IS KNOWN ALREADY: Successful establishment of pregnancy requires HESCs to transform from fibroblastic to epithelioid cells in a process called decidualization...
September 1, 2017: Molecular Human Reproduction
https://www.readbyqxmd.com/read/28887272/establishing-benchmarks-for-the-volume-outcome-relationship-for-common-lumbar-spine-surgical-procedures
#15
Andrew J Schoenfeld, Daniel J Sturgeon, Camden B Burns, Tyler J Hunt, Christopher M Bono
BACKGROUND CONTEXT: The importance of surgeon volume as a quality measure has been defined for a number of surgical specialties. Meaningful procedural volume benchmarks have not been established, however, particularly with respect to lumbar spine surgery. PURPOSE: We aimed to establish surgeon volume benchmarks for the performance of four common lumbar spine surgical procedures (discectomy, decompression, lumbar interbody fusion, and lumbar posterolateral fusion)...
September 5, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28886442/four-new-cases-of-pediatric-thoracic-aortic-aneurysm-taa-with-review-of-the-molecular-genetic-basis-utilizing-the-newly-published-consensus-nomenclature
#16
Shriprasad Deshpande, Adina Alazraki, Nasim Khoshnam, Diana Kantarovich, Pooya Hoseinzadeh, Camden Hebson, Ajay Bhatia, Lauren Schaffer, Elana Maccou, Bahig M Shehata
The majority of thoracic aortic aneurysms (TAA) in the pediatric population are due to post repair etiology (iatrogenic). Although rare, underlying inheritable disease and congenital cardiac anomalies represent the most common non-iatrogenic cause of TAA among patients in this age group (1-21 years of age). Herein, we present a case series of 9aortic aneurysms with varying underlying etiology. We discuss the molecular genetic basis of these syndromes in conjunction with the radiological findings and histological description utilizing the newly published consensus criteria article...
July 27, 2017: Cardiovascular Pathology: the Official Journal of the Society for Cardiovascular Pathology
https://www.readbyqxmd.com/read/28882279/benefit-cost-analysis-of-lane-departure-warning-and-roll-stability-control-in-commercial-vehicles
#17
Alejandra Medina-Flintsch, Jeffrey S Hickman, Feng Guo, Matthew C Camden, Richard J Hanowski, Quon Kwan
INTRODUCTION: This paper presents the cost benefits of two different onboard safety systems (OSS) installed on trucks as they operated during normal revenue deliveries. Using a formal economic analysis approach, the study quantified the costs and benefits associated with lane departure warning (LDW) systems and roll stability control (RSC) systems. METHODS: The study used data collected from participating carriers (many of these crashes were not reported to state or Federal agencies), and the research team also reviewed each crash file to determine if the specific OSS would have mitigated or prevented the crash...
September 2017: Journal of Safety Research
https://www.readbyqxmd.com/read/28875062/interactions-between-energy-drink-consumption-and-sleep-problems-associations-with-alcohol-use-among-young-adolescents
#18
Naomi R Marmorstein
Background: Energy drink consumption and sleep problems are both associated with alcohol use among adolescents. In addition, caffeine consumption (including energy drinks) is associated with sleep problems. However, information about how these three constructs may interact is limited. The goal of this study was to examine potential interactions between energy drink consumption and sleep problems in the concurrent prediction of alcohol use among young adolescents. Coffee and soda consumption were also examined for comparison...
September 1, 2017: Journal of Caffeine Research
https://www.readbyqxmd.com/read/28827277/an-investigation-of-the-predictors-of-photoprotection-and-uvr-dose-to-the-face-in-patients-with-xp-a-protocol-using-observational-mixed-methods
#19
Jessica Walburn, Robert Sarkany, Sam Norton, Lesley Foster, Myfanwy Morgan, Kirby Sainsbury, Vera Araújo-Soares, Rebecca Anderson, Isabel Garrood, Jakob Heydenreich, Falko F Sniehotta, Rute Vieira, Hans Christian Wulf, John Weinman
INTRODUCTION: Xeroderma pigmentosum (XP) is a rare genetic condition caused by defective nucleotide excision repair and characterised by skin cancer, ocular and neurological involvement. Stringent ultraviolet protection is the only way to prevent skin cancer. Despite the risks, some patients' photoprotection is poor, with a potentially devastating impact on their prognosis. The aim of this research is to identify disease-specific and psychosocial predictors of photoprotection behaviour and ultraviolet radiation (UVR) dose to the face...
August 21, 2017: BMJ Open
https://www.readbyqxmd.com/read/28814388/impact-of-poxvirus-vector-priming-protein-coadministration-and-vaccine-intervals-on-hiv-gp120-vaccine-elicited-antibody-magnitude-and-function-in-infant-macaques
#20
Bonnie Phillips, Genevieve G Fouda, Josh Eudailey, Justin Pollara, Alan D Curtis, Erika Kunz, Maria Dennis, Xiaoying Shen, Camden Bay, Michael Hudgens, David Pickup, S Munir Alam, Amir Ardeshir, Pamela A Kozlowski, Koen K A Van Rompay, Guido Ferrari, M Anthony Moody, Sallie Permar, Kristina De Paris
Despite success in reducing vertical HIV transmission by maternal antiretroviral therapy, several obstacles limit its efficacy during breastfeeding, and breast-milk transmission is now the dominant mode of mother-to-child transmission (MTCT) of HIV in infants. Thus, a pediatric vaccine is needed to eradicate oral HIV infections in newborns and infants. Utilizing the infant rhesus macaque model, we compared 3 different vaccine regimens: (i) HIV envelope (Env) protein only, (ii) poxvirus vector (modified vaccinia virus Ankara [MVA])-HIV Env prime and HIV Env boost, and (iii) coadministration of HIV Env and MVA-HIV Env at all time points...
October 2017: Clinical and Vaccine Immunology: CVI
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