Weiwei Zhao, Ya-Peng Wang, Xinlong Tang, Yi Jiang, Yunxing Xue, Yali Wang, Qiuju Ding, Huimei Chen, Dongjin Wang, YongQing Cheng, Min Ge, Qing Zhou
BACKGROUND: Postoperative acute kidney injury (PO-AKI) is a prevalent complication among patients with acute type A aortic dissection (aTAAD) for which unrecognized trajectories of renal function recovery, and their heterogeneity, may underpin poor success in identifying effective therapies. METHODS: This was a retrospective, single-center cohort study in a regional Great Vessel Center including patients undergoing aortic dissection surgery. Estimated glomerular filtration rate (eGFR) recovery trajectories of PO-AKI were defined through the unsupervised latent class mixture modeling (LCMM), with an assessment of patient and procedural characteristics, complications, and early-term survival...
2024: Frontiers in Cardiovascular Medicine