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https://www.readbyqxmd.com/read/29793121/head-coaches-attitudes-towards-injury-prevention-and-use-of-related-methods-in-professional-basketball-a-survey
#1
J Wilke, D Niederer, L Vogt, W Banzer
OBJECTIVES: To investigate the practices and attitudes of professional basketball head coaches towards injury prevention. DESIGN: Survey. SETTING: Elite-level basketball. PARTICIPANTS: Head coaches of all 366 German professional teams. MAIN OUTCOME MEASURES: Use of injury risk screening methods, rated importance of different musculoskeletal injuries and rated effectiveness of preventive interventions...
April 17, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29793034/a-case-control-study-about-foetal-trauma-during-cesarean-delivery
#2
Enora Dolivet, Cécile Delesalle, Rémi Morello, Marie Blouet, Corinne Bronfen, Michel Dreyfus, Guillaume Benoist
OBJECTIVE: The caesarean section rate is gradually increasing in most countries. The frequency of occurrence of foetal injury per birth is estimated to 1%. The majority of these injuries presents a low functional impact, but remains responsible for a significant neonatal morbidity. Even though the foetal risk factors are well documented in cases of vaginal birth, they have not been accurately identified for cesarean section. The aim of this study is to identify the risk factors for neonatal fracture during caesarean section...
May 21, 2018: Journal of Gynecology Obstetrics and Human Reproduction
https://www.readbyqxmd.com/read/29792925/change-in-patient-reported-outcomes-in-patients-with-and-without-mechanical-symptoms-undergoing-arthroscopic-meniscal-surgery-a-prospective-cohort-study
#3
Kenneth Pihl, Aleksandra Turkiewicz, Martin Englund, L Stefan Lohmander, Uffe Jørgensen, Nis Nissen, Jeppe Schjerning, Jonas B Thorlund
OBJECTIVE: Patients with degenerative or traumatic meniscal tears are at high risk of developing knee osteoarthritis. We investigated if younger (≤40 years) and older (>40 years) patients with preoperative mechanical symptoms improved more in patient-reported outcomes after meniscal surgery than those without mechanical symptoms. DESIGN: Patients from Knee Arthroscopy Cohort Southern Denmark (KACS) undergoing arthroscopic surgery for a meniscal tear completed online questionnaires before surgery, and at 12 and 52 weeks follow-up...
May 21, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29792895/pharmacogenomics-of-drug-induced-liver-injury-dili-molecular-biology-to-clinical-applications
#4
REVIEW
Kalaiyarasi Kaliyaperumal, Jane I Grove, Robin M Delahay, William J H Griffiths, Adam Duckworth, Guruprasad P Aithal
A number of drug-specific and host-related factors contribute to the development of drug-induced liver injury (DILI). Investigations focused on genetic susceptibility to DILI have advanced our understanding of the pathogenesis of this rare, yet potentially life-threatening adverse reaction. Candidate gene studies involving well-characterized patients with DILI and drug-exposed controls have identified single nucleotide polymorphisms (SNPs) affecting the metabolism and clearance of specific drugs and hence, influencing individual's susceptibility to DILI...
May 21, 2018: Journal of Hepatology
https://www.readbyqxmd.com/read/29792569/the-relationship-between-suicidal-responses-and-traumatic-brain-injury-and-severe-insomnia-in-active-duty-veteran-and-civilian-populations
#5
Kelly A Soberay, Jetta E Hanson, Megan Dwyer, E Ashby Plant, Peter M Gutierrez
OBJECTIVE: This study examined how a positive traumatic brain injury (TBI) screening and insomnia severity relates to suicidal outcomes across active duty, veteran, and civilian samples. METHODS: Data were used from 3,993 participants from 19 studies. We conducted a series of analyses by group to identify which significantly differed on the variables of interest. RESULTS: TBI and insomnia each had independent relationships with outcomes over and above the impact of the other factor...
May 24, 2018: Archives of Suicide Research: Official Journal of the International Academy for Suicide Research
https://www.readbyqxmd.com/read/29792528/dissociation-of-cerebrospinal-fluid-amyloid-%C3%AE-and-tau-levels-in-patients-with-prolonged-posttraumatic-disorders-of-consciousness
#6
Sergio Bagnato, Maria Andriolo, Cristina Boccagni, Antonino Sant'Angelo, Maria Enza D'Ippolito, Giuseppe Galardi
BACKGROUND: Traumatic brain injury (TBI) is a major risk factor for Alzheimer's disease (AD). Although the mechanisms that lead to AD after a TBI are unclear, we hypothesize that changes in amyloid-β (Aβ) metabolism and abnormal tau phosphorylation are reasonable candidates. OBJECTIVE: To investigate Aβ and tau dynamics in the chronic phase of TBI. METHODS: We evaluated Aβ1-42 , total tau (t-tau), and phosphorylated tau (p-tau) levels in the cerebrospinal fluid (CSF) of 15 patients who developed a prolonged disorder of consciousness after a severe TBI (mean time from TBI 271...
May 24, 2018: Brain Injury: [BI]
https://www.readbyqxmd.com/read/29792520/changes-in-the-neurovascular-anatomy-of-the-shoulder-after-an-open-latarjet-procedure-defining-a-surgical-safe-zone
#7
Christopher M LaPrade, Andrew S Bernhardson, Zachary S Aman, Gilbert Moatshe, Jorge Chahla, Grant J Dornan, Robert F LaPrade, Matthew T Provencher
BACKGROUND: Although previous literature has described the relevant anatomy for an open anterior Bankart approach of the shoulder, there is little known regarding the anatomic relationship changes in the neurovascular structures after an open Latarjet procedure. PURPOSE: To define the neurovascular anatomy of the native shoulder in relation to the coracoid and to define the anatomy after the Latarjet procedure in relation to the glenoid to determine distances to these neurovascular structures with and without neurolysis of the musculocutaneous nerve (MCN) from the conjoint tendon...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29792394/concomitant-administration-of-candesartan-cilexetil-in-patients-on-paclitaxel-and-carboplatin-combination-therapy-increases-risk-of-severe-neutropenia
#8
Yurie Katsube, Daiki Hira, Masayuki Tsujimoto, Hiroyoshi Koide, Tetsuya Minegaki, Yoshito Ikeda, Shin-Ya Morita, Kohshi Nishiguchi, Tomohiro Terada
OBJECTIVE: Angiotensin receptor blockers (ARBs) are often used in patients on paclitaxel (PTX) and carboplatin combination (TC) therapy to treat hypertension caused by the co-administration of bevacizumab. The aim of this retrospective study was to analyze the association between co-administration of ARBs and the development of severe neutropenia in patients on TC therapy. MATERIALS AND METHODS: In this study, 211 concomitant medications were prescribed to 173 patients on TC therapy...
May 24, 2018: International Journal of Clinical Pharmacology and Therapeutics
https://www.readbyqxmd.com/read/29792393/outcomes-of-transcatheter-aortic-valve-implantation-compared-with-surgical-aortic-valve-replacement-in-geriatric-patients-with-chronic-kidney-disease
#9
Linda Shavit, Shuli Silberman, Rachel Tauber, Ofer Merin, Daniel Bitran, Daniel Fink
BACKGROUND: Transcatheter aortic valve implantation (TAVI) is a less invasive treatment modality for patients with severe aortic valve stenosis (AS) who are at a higher risk if they have surgery. Preoperative chronic kidney disease (CKD) influences outcomes of cardiac surgery and is associated with a higher mortality and more complicated hospital course. The aims of our study were to evaluate the comparative outcomes of TAVI versus surgical aortic valve replacement (SAVR) in geriatric patients with preoperative CKD...
May 24, 2018: Clinical Nephrology
https://www.readbyqxmd.com/read/29792215/adding-left-atrial-appendage-closure-to-open-heart-surgery-provides-protection-from-ischemic-brain-injury-six-years-after-surgery-independently-of-atrial-fibrillation-history-the-laacs-randomized-study
#10
Jesper Park-Hansen, Susanne J V Holme, Akhmadjon Irmukhamedov, Christian L Carranza, Anders M Greve, Gina Al-Farra, Robert G C Riis, Brian Nilsson, Johan S R Clausen, Anne S Nørskov, Christina R Kruuse, Egill Rostrup, Helena Dominguez
BACKGROUND: Open heart surgery is associated with high occurrence of atrial fibrillation (AF), subsequently increasing the risk of post-operative ischemic stroke. Concomitant with open heart surgery, a cardiac ablation procedure is commonly performed in patients with known AF, often followed by left atrial appendage closure with surgery (LAACS). However, the protective effect of LAACS on the risk of cerebral ischemia following cardiac surgery remains controversial. We have studied whether LAACS in addition to open heart surgery protects against post-operative ischemic brain injury regardless of a previous AF diagnosis...
May 23, 2018: Journal of Cardiothoracic Surgery
https://www.readbyqxmd.com/read/29792105/risk-factors-for-groin-injury-and-symptoms-in-elite-level-soccer-players-a-cohort-study-in-the-dutch-professional-leagues
#11
Rob Langhout, Igor Tak, Anne-Marie van Beijsterveldt, Martijn Ricken, Adam Weir, Maarten Barendrecht, Gino Kerkhoffs, Janine Stubbe
Study Design Cohort study with prospective and retrospective elements. Background Groin injury and symptoms are common in soccer players. Their relationship with reduced hip range of motion (ROM) and previous injury is unclear. Objectives To conduct a retrospective assessment of associations between previous injury and pre-season hip ROM and pre-season prevalence of severe groin symptoms; and prospective identification of risk factors for within-season groin injury. Methods During 2015-2016, 190 players from 9 Dutch professional soccer clubs participated...
May 23, 2018: Journal of Orthopaedic and Sports Physical Therapy
https://www.readbyqxmd.com/read/29791977/no-association-between-rate-of-torque-development-and-onset-of-muscle-activity-with-increased-risk-of-hamstring-injury-in-elite-football
#12
Nicol van Dyk, Roald Bahr, Angus F Burnett, Evert Verhagen, Damien von Tiggelen, Erik Witvrouw
INTRODUCTION: Hamstring injuries remain a significant burden in sports that involve high speed running. In elite male football, hamstring injury has repeatedly been identified as the most common noncontact injury, representing 12% of all injuries. As the incidence remains high, investigations are aimed at better understanding how to improve prevention efforts. Intrinsic risk factors such as strength have been investigated extensively in a cohort of professional football players; however, other intrinsic measures of neuromuscular function have not been studied in this cohort...
May 23, 2018: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/29791695/current-strategies-to-prevent-iatrogenic-ureteral-injury-during-colorectal-surgery
#13
Jonathan Douissard, Frederic Ris, Philippe Morel, Nicolas Christian Buchs
Iatrogenic ureteral injuries are a source of major concern among surgeons performing colorectal procedures. Although they are uncommon, these lesions lead to severe morbidity and long-term functional disabilities, as well as an increase in mortality, hospital stay, and cost. The laparoscopic approach has gained popularity in the field of colorectal surgery and is associated with improved global postoperative outcomes. However, it is also considered to increase the risk of ureteral injury when compared to open surgery, especially during left colonic and rectal resections...
June 1, 2018: Surgical Technology International
https://www.readbyqxmd.com/read/29791183/a-2-year-prospective-cohort-study-of-overuse-running-injuries-the-runners-and-injury-longitudinal-study-trails
#14
Stephen P Messier, David F Martin, Shannon L Mihalko, Edward Ip, Paul DeVita, D Wayne Cannon, Monica Love, Danielle Beringer, Santiago Saldana, Rebecca E Fellin, Joseph F Seay
BACKGROUND: The National Center for Injury Prevention and Control, noting flaws in previous running injury research, called for more rigorous prospective designs and comprehensive analyses to define the origin of running injuries. PURPOSE: To determine the risk factors that differentiate recreational runners who remain uninjured from those diagnosed with an overuse running injury during a 2-year observational period. STUDY DESIGN: Cohort study; Level of evidence, 2...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29791182/season-ending-shoulder-injuries-in-the-national-collegiate-athletic-association-data-from-the-ncaa-injury-surveillance-program-2009-2010-through-2013-2014
#15
Avi D Goodman, Steven F DeFroda, Joseph A Gil, Justin E Kleiner, Neill Y Li, Brett D Owens
BACKGROUND: Examination of the incidence of shoulder season-ending injury (SEI) in the collegiate athlete population is limited. PURPOSE: To determine the incidence of shoulder SEI in the National Collegiate Athletic Association (NCAA) and to investigate the risk factors for a shoulder injury ending an athlete's season. STUDY DESIGN: Descriptive epidemiology study. METHODS: All shoulder injuries from the NCAA Injury Surveillance Program database for the years 2009-2010 to 2013-2014 were extracted, and SEI status was noted...
May 1, 2018: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/29791174/-drug-and-herbal-hepatotoxicity-an-overview-of-clinical-classifications
#16
Mária Szántová, Jozef Sedlačko, Martina Jakabovičová
Drug induced liver injury (DILI) is often underdiagnosed disease with increasing incidence. In developed countries it belongs to the leading causes of acute liver failure. Risk groups are women and persons older than 60 years. The work summarizes the up to date information on diagnosis and mostly used classifications on DILI. It is quite often and serious complication of medicament therapy. DILI belongs to the most often cause of acute hepatic failure in the old age in developed countries. Diagnostic procedure includes medical history (time correlation with drug intake), clinical symptoms and blood tests...
2018: Vnitr̆ní Lékar̆ství
https://www.readbyqxmd.com/read/29791072/massive-hemothorax-after-computed-tomography-guided-lung-tumor-biopsy-an-unusual-but-disastrous-complication
#17
Wei-Ming Huang, Hui-Chen Lin, Chia-Hung Chen, Chien-Wen Chen, Chih-Hsin Wang, Chung-Yao Huang, Ching-Che Wang, Chun-Chao Huang
Intercostal artery injury during transthoracic puncture is rare but is accompanied by high rates of morbidity and mortality. We report a case with metachronous double primary esophageal cancers and development of multiple lung nodules. Tissue proof for the lung nodules is required to guide the following treatment protocol. Our patient died soon after computed tomography-guided lung tumor biopsy was performed, as a result of procedure-related massive and uncontrolled hemothorax. The cause is likely intercostal artery injury related to the transthoracic puncture...
May 23, 2018: Thoracic Cancer
https://www.readbyqxmd.com/read/29791065/risk-factors-of-valproic-acid-induced-hyperammonaemia-in-chinese-paediatric-patients-with-epilepsy
#18
Xu Zhu, Xinlin Li, Ti Zhang, Limei Zhao
The present study was aimed at identifying genetic and non-genetic risk factors for valproic acid (VPA)-induced hyperammonaemia in Chinese paediatric patients with epilepsy. A total of 210 epileptic patients, treated with VPA as monotherapy, were enrolled and classified into hyperammonaemia and control groups according to their blood ammonia level (cut-off value 50 μmol/L). Serum concentrations of VPA and its major metabolites were simultaneously determined by ultra-high performance liquid chromatography-tandem mass spectrometry...
May 23, 2018: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/29790961/increased-vulnerability-to-attentional-failure-during-acute-sleep-deprivation-in-women-depends-on-menstrual-phase
#19
Parisa Vidafar, Joshua J Gooley, Angus C Burns, Shantha M W Rajaratnam, Melanie Rueger, Eliza Van Reen, Charles A Czeisler, Steven W Lockley, Sean W Cain
Study Objectives: Investigate sex differences in the effect of sleep deprivation on performance, accounting for menstrual phase in women. Methods: We examined alertness data from 124 healthy women and men (40 women, 84 men; aged 18 - 30 years) who maintained wakefulness for at least 30 hours in a laboratory setting using a constant routine protocol. Objective alertness was assessed every two hours using a 10-minute Psychomotor Vigilance Task. Subjective alertness was assessed every hour via the Karolinska Sleepiness Scale...
May 22, 2018: Sleep
https://www.readbyqxmd.com/read/29789993/the-role-of-the-epithelial-to-mesenchymal-transition-emt-in-diseases-of-the-salivary-glands
#20
REVIEW
Margherita Sisto, Sabrina Lisi, Domenico Ribatti
The link between inflammatory microenvironment and cancer emerged in the last years as a decisive factor in the induction of the pathological epithelial-mesenchymal transition (EMT). The EMT induces changes of cell states converting the epithelial cells to mesenchymal cells when this program is fully executed and EMT has emerged as a central driver of tumor malignancy. Cellular pathways activated by chronic inflammation brought about by chronic infections, by immune-mediated diseases, or by dysregulated wound healing at sites of repetitive tissue injury, constitute risk factors or initial cell transformation and for cancer progression...
May 23, 2018: Histochemistry and Cell Biology
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