keyword
MENU ▼
Read by QxMD icon Read
search

N-a

keyword
https://www.readbyqxmd.com/read/29352175/magnetic-vortices-as-efficient-nano-heaters-in-magnetic-nanoparticle-hyperthermia
#1
N A Usov, M S Nesmeyanov, V P Tarasov
Magnetic vortices existing in soft magnetic nanoparticles with sizes larger than the single-domain diameter can be efficient nano-heaters in biomedical applications. Using micromagnetic numerical simulation we prove that in the optimal range of particle diameters the magnetization reversal of the vortices in spherical iron and magnetite nanoparticles is possible for moderate amplitudes of external alternating magnetic field, H0 < 100 Oe. In contrast to the case of superparamagnetic nanoparticles, for the vortex configuration the hysteresis loop area increases as a function of frequency...
January 19, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29351172/a-systematic-review-and-meta-analysis-of-genetic-risk-factors-for-neuropathic-pain
#2
Abirami Veluchamy, Harry L Hébert, Weihua Meng, Colin N A Palmer, Blair H Smith
Neuropathic pain (NP) is an increasingly common chronic pain state and a major health burden, affecting approximately 7-10% of the general population. Emerging evidence suggests that genetic factors could partially explain individual susceptibility to NP and the estimated heritability in twins is 37%. The aim of this study was to systematically review and summarize the studies in humans that have investigated the influence of genetic factors associated with NP. We conducted a comprehensive literature search and performed meta-analyses of all the potential genetic variants associated with NP...
January 18, 2018: Pain
https://www.readbyqxmd.com/read/29350574/dr-william-gerald-dyer-27-october-1929-18-june-2006
#3
William J Poly, Richard Dyer
N/A.
January 19, 2018: Journal of Parasitology
https://www.readbyqxmd.com/read/29349782/new-species-of-the-genus-spectracanthicus-loricariidae-hypostominae-ancistrini-from-the-rio-java%C3%A3-s-rio-araguaia-basin-with-a-description-of-gross-brain-morphology
#4
C C Chamon, T N A Pereira, M B Mendonça, A Akama
A new species of Spectracanthicus is described from the Rio Javaés, Rio Araguaia basin. The new species is distinguished from its congeners (except Spectracanthicus immaculatus) by colour pattern: body dark grey to dark brown without dots or blotches (v. body colour with yellowish small dots in Spectracanthicus murinus, Spectracanthicus punctatissimus and Spectracanthicus tocantinensis and large white dots in Spectracanthicus zuanoni). It can be further distinguished from S. immaculatus by having thicker and less numerous teeth, with up to eight premaxillary and 20 dentary teeth (v...
January 18, 2018: Journal of Fish Biology
https://www.readbyqxmd.com/read/29347423/rayleigh-taylor-instability-in-accelerated-elastic-solid-slabs
#5
S A Piriz, A R Piriz, N A Tahir
We develop the linear theory for the asymptotic growth of the incompressible Rayleigh-Taylor instability of an accelerated solid slab of density ρ_{2}, shear modulus G, and thickness h, placed over a semi-infinite ideal fluid of density ρ_{1}<ρ_{2}. It extends previous results for Atwood number A_{T}=1 [B. J. Plohr and D. H. Sharp, Z. Angew. Math. Phys. 49, 786 (1998)ZAMPA80044-227510.1007/s000330050121] to arbitrary values of A_{T} and unveil the singular feature of an instability threshold below which the slab is stable for any perturbation wavelength...
December 2017: Physical Review. E
https://www.readbyqxmd.com/read/29347027/thermal-gas-rectification-using-a-sawtooth-channel
#6
S Solórzano, N A M Araújo, H J Herrmann
We study the rectification of a two-dimensional thermal gas in a channel of asymmetric dissipative walls. For an ensemble of smooth Lennard-Jones particles, our numerical simulations reveal a nonmonotonic dependence of the flux on the thermostat temperature, channel asymmetry, and particle density, with three distinct regimes. Theoretical arguments are developed to shed light on the functional dependence of the flux on the model parameters.
September 2017: Physical Review. E
https://www.readbyqxmd.com/read/29343235/comparison-of-three-assembly-strategies-for-a-heterozygous-seedless-grapevine-genome-assembly
#7
Sagar Patel, Zhixiu Lu, Xiaozhu Jin, Padmapriya Swaminathan, Erliang Zeng, Anne Y Fennell
BACKGROUND: De novo heterozygous assembly is an ongoing challenge requiring improved assembly approaches. In this study, three strategies were used to develop de novo Vitis vinifera 'Sultanina' genome assemblies for comparison with the inbred V. vinifera (PN40024 12X.v2) reference genome and a published Sultanina ALLPATHS-LG assembly (AP). The strategies were: 1) a default PLATANUS assembly (PLAT_d) for direct comparison with AP assembly, 2) an iterative merging strategy using METASSEMBLER to combine PLAT_d and AP assemblies (MERGE) and 3) PLATANUS parameter modifications plus GapCloser (PLAT*_GC)...
January 17, 2018: BMC Genomics
https://www.readbyqxmd.com/read/29341851/underutilization-of-supplemental-magnetic-resonance-imaging-screening-among-patients-at-high-breast-cancer-risk
#8
Randy Miles, Fei Wan, Tracy L Onega, Amanda Lenderink-Carpenter, Ellen S O'Meara, Weiwei Zhu, Louise M Henderson, Jennifer S Haas, Deirdre A Hill, Anna N A Tosteson, Karen J Wernli, Jennifer Alford-Teaster, Janie M Lee, Constance D Lehman, Christoph I Lee
BACKGROUND: Women at high lifetime breast cancer risk may benefit from supplemental breast magnetic resonance imaging (MRI) screening, in addition to routine mammography screening for earlier cancer detection. MATERIALS AND METHODS: We performed a cross-sectional study of 422,406 women undergoing routine mammography screening across 86 Breast Cancer Surveillance Consortium (BCSC) facilities during calendar year 2012. We determined availability and use of on-site screening breast MRI services based on woman-level characteristics, including >20% lifetime absolute risk using the National Cancer Institute risk assessment tool...
January 17, 2018: Journal of Women's Health
https://www.readbyqxmd.com/read/29340521/organic-solvent-exposure-and-contrast-sensitivity-comparing-men-and-women
#9
A R Oliveira, A A Campos Neto, M J O de Andrade, P C B de Medeiros, N A Dos Santos
The goal of this study was to compare the visual contrast sensitivity (CS) of men and women exposed and not exposed to organic solvents. Forty-six volunteers of both genders aged between 18 and 41 years (mean±SD=27.72±6.28) participated. Gas station attendants were exposed to gas containing 46.30 ppm of solvents at a temperature of 304±274.39 K, humidity of 62.25±7.59% and ventilation of 0.69±0.46 m/s (a passive gas chromatography-based sampling method was used considering the microclimate variables). Visual CS was measured via the psychophysical method of two-alternative forced choice using vertical sinusoidal gratings with spatial frequencies of 0...
January 11, 2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
https://www.readbyqxmd.com/read/29340220/multilocus-analysis-of-genetic-susceptibility-to-myocardial-infarction-in-russians-replication-study
#10
N G Kukava, B V Titov, G J Osmak, N A Matveeva, O G Kulakova, A V Favorov, R M Shakhnovich, M Ya Ruda, O O Favorova
In search of genetic markers of myocardial infarction (MI) risk, which have prognostic significance for Russians, we performed a replication study of MI association with genetic variants of PCSK9 (rs562556), APOE (epsilon polymorphism, rs7412 and rs429358), LPL (rs320), MTHFR (rs1801133), eNOS (rs2070744), and the 9p21 region (rs1333049) in 405 patients with MI and 198 controls. Significant MI association was observed with variants of the lipid metabolism genes (PCSK9, APOE and LPL), and of eNOS. The SNPs in the MTHFR gene and the 9p21 region were not significantly associated with MI one by one but were included in several different MI-associated allelic combinations identified by multilocus analysis...
October 2017: Acta Naturae
https://www.readbyqxmd.com/read/29340217/translational-cross-activation-of-the-encapsidated-rna-of-potexviruses
#11
M V Arkhipenko, N A Nikitin, E K Donchenko, O V Karpova, J G Atabekov
We had shown the genomic RNA of potexviruses potato virus X and the alternanthera mosaic virus to be inaccessible in vitro to ribosomes while in intact virion form, but the RNAs can be translationally activated following the binding of movement protein 1 (MP1) to virus particles. Here, we present the results of the follow-up study targeting two more potexvirus species - the Narcissus mosaic virus and the Potato aucuba mosaic virus. We found encapsidated potexviral RNA to share common translational features in vitro and the MP1 to be potent over homological virions of its "own" species and over heterological virions of other species, as well exhibiting selective specificity...
October 2017: Acta Naturae
https://www.readbyqxmd.com/read/29338132/tumour-thickness-diameter-area-or-volume-the-prognostic-significance-of-conventional-versus-digital-image-analysis-based-size-estimation-methods-in-uveal-melanoma
#12
Thorsteinn Snaebjörnsson Arnljots, Zaid Al-Sharbaty, Emma Lardner, Charlotta All-Eriksson, Stefan Seregard, Gustav Stålhammar
PURPOSE: The aim of this study was to compare conventional and novel size estimation methods' ability to predict survival in uveal melanoma (UM). METHODS: The study was designed as a retrospective consecutive chart review of patients with UM, enucleated between the years 1984 and 1993. Area and volume were estimated based on the largest histopathological cross-section, the second centroid theorem of Pappus and digital image analysis, correlated to overall and relative survival...
January 16, 2018: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29336872/abundance-of-ribosomal-rna-gene-copies-in-the-genomes-of-schizophrenia-patients
#13
I V Chestkov, E M Jestkova, E S Ershova, V E Golimbet, T V Lezheiko, N Y Kolesina, L N Porokhovnik, N A Lyapunova, V L Izhevskaya, S I Kutsev, N N Veiko, S V Kostyuk
OBJECTIVE: The ribosome is a critical component of the translation machinery. The key component of ribosomes is ribosomal RNA (rRNA). Dysregulation of rRNA biogenesis has been implicated in some human diseases. One of the factors affecting rRNA biogenesis is the ribosomal RNA genes (rDNA) copy number in the genome. The aim of this study was to examine the rDNA copy number (CN) variation in the genomes of patients with schizophrenia (SZ) compared to healthy controls (HC). METHODS: We evaluated rDNA CN in leukocytes of 179 subjects with SZ (108 male/71 female) in comparison with 122 HC (60 male/62 female) using two techniques: qPCR and nonradioactive quantitative hybridization (NQH), which is based on the use of biotinylated rDNA probes...
January 11, 2018: Schizophrenia Research
https://www.readbyqxmd.com/read/29336444/the-structural-diversity-of-c-rich-dna-aggregates-unusual-self-assembly-of-beetle-like-nanostructures
#14
A D Protopopova, V B Tsvetkov, A M Varizhuk, N A Barinov, V V Podgorsky, D V Klinov, G E Pozmogova
We studied the ability of oligonucleotides CnT25 (n = 2, 5, 7, 9, 12, 25) to form an intermolecular i-motif using circular dichroism, ultra-violet spectroscopy, nuclear magnetic resonance, high-resolution atomic force microscopy, high-performance liquid chromatography, and molecular dynamics simulations. The arrangement of single-stranded oligonucleotides in multimer i-motifs was very unusual: C-tracts of different oligonucleotides followed each other consecutively in order to fold into a closed intermolecular i-motif core with minimal loops (one cytidine in a loop spanning over a minor groove, three cytidines in a loop over a major groove); intact T-tracts protruded from predefined loci allowing visualization of beetle-like nanostructures by atomic force microscopy...
January 16, 2018: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/29334524/leveraging-linkage-of-cohort-studies-with-administrative-claims-data-to-identify-individuals-with-cancer
#15
Mackenzie R Bronson, Nirav S Kapadia, Andrea M Austin, Qianfei Wang, Diane Feskanich, Julie P W Bynum, Francine Grodstein, Anna N A Tosteson
BACKGROUND: In an effort to overcome quality and cost constraints inherent in population-based research, diverse data sources are increasingly being combined. In this paper, we describe the performance of a Medicare claims-based incident cancer identification algorithm in comparison with observational cohort data from the Nurses' Health Study (NHS). METHODS: NHS-Medicare linked participants' claims data were analyzed using 4 versions of a cancer identification algorithm across 3 cancer sites (breast, colorectal, and lung)...
January 12, 2018: Medical Care
https://www.readbyqxmd.com/read/29333665/clinical-and-metabolic-effects-associated-with-weight-changes-and-obeticholic-acid-in-non-alcoholic-steatohepatitis
#16
B Hameed, N A Terrault, R M Gill, R Loomba, N Chalasani, J H Hoofnagle, M L Van Natta
BACKGROUND: In a 72-week, randomised controlled trial of obeticholic acid (OCA) in non-alcoholic steatohepatitis (NASH), OCA was superior to placebo in improving serum ALT levels and liver histology. OCA therapy also reduced weight. AIMS: Because weight loss by itself can improve histology, to perform a post hoc analysis of the effects of weight loss and OCA treatment in improving clinical and metabolic features of NASH. METHODS: The analysis was limited to the 200 patients with baseline and end-of-treatment liver biopsies...
January 14, 2018: Alimentary Pharmacology & Therapeutics
https://www.readbyqxmd.com/read/29329073/nanobiostructure-of-fibrous-like-alumina-functionalized-with-an-analog-of-the-bp100-peptide-synthesis-characterization-and-biological-applications
#17
L M F C Torres, N A Braga, I P Gomes, M T Almeida, T L Santos, J P de Mesquita, L M da Silva, H R Martins, K C Kato, W T P Dos Santos, J M Resende, M C Pereira, M P Bemquerer, M A Rodrigues, R M Verly
The functionalization of alumina nanoparticles of specific morphology with antimicrobial peptides (AMP) can be a promising strategy for modeling medical devices and packaging materials for cosmetics, medicines or food, since the contamination by pathogens could be reduced. In this paper, we show the synthesis of a fibrous-like alumina nanobiostructure, as well as its functionalization with the peptide EAAA-BP100, an analog of the antimicrobial peptide BP100. The antibacterial activity of the obtained material against some bacterial strains is also investigated...
January 3, 2018: Colloids and Surfaces. B, Biointerfaces
https://www.readbyqxmd.com/read/29328709/topological-vortex-and-knotted-dissipative-optical-3d-solitons-generated-by-2d-vortex-solitons
#18
N A Veretenov, S V Fedorov, N N Rosanov
We predict a new class of three-dimensional (3D) topological dissipative optical one-component solitons in homogeneous laser media with fast saturable absorption. Their skeletons formed by vortex lines where the field vanishes are tangles, i.e., N_{c} knotted or unknotted, linked or unlinked closed lines and M unclosed lines that thread all the closed lines and end at the infinitely far soliton periphery. They are generated by embedding two-dimensional laser solitons or their complexes in 3D space after their rotation around an unclosed, infinite vortex line with topological charge M_{0} (N_{c}, M, and M_{0} are integers)...
December 29, 2017: Physical Review Letters
https://www.readbyqxmd.com/read/29325127/inhibiting-trophoblast-par-1-overexpression-suppresses-sflt-1-induced-anti-angiogenesis-and-abnormal-vascular-remodeling-a-possible-therapeutic-approach-for-preeclampsia
#19
Yin Zhao, YanFang Zheng, XiaoXia Liu, QingQing Luo, Di Wu, XiaoPing Liu, Li Zou
STUDY QUESTION: Is it possible to improve vascular remodeling by inhibiting the excessive expression of protease activated receptor 1 (PAR-1) in trophoblast of abnormal placenta? SUMMARY ANSWER: Inhibition of trophoblast PAR-1 overexpression may promote placental angiogenesis and vascular remodeling, offering an alternative therapeutic approach for preeclampsia. WHAT IS KNOWN ALREADY: PAR-1 is high-affinity receptor of thrombin. Thrombin increases sFlt-1 secretion in trophoblast via the activation of PAR-1...
January 9, 2018: Molecular Human Reproduction
https://www.readbyqxmd.com/read/29322983/auditory-p300-event-related-potential-normative-data-in-the-indian-population
#20
N A Uvais, S Haque Nizamie, Basudeb Das, Samir K Praharaj, Mohammad Zia Ul Haq Katshu
OBJECTIVE: To generate the normative data of auditory P300 event-related potential for various age groups in the Indian population. MATERIALS AND METHODS: Auditory P300 event-related potentials, using the oddball paradigm, of healthy control participants in studies carried out at our institute were included to generate normative data in the age range of 10-50 years. The amplitude and latency of P300 for Fz, Cz, and Pz were selected for analysis. RESULTS: For P300 amplitude, overall multivariate analysis of variance (MANOVA) was significant [Pillai's Trace F (9/453) = 3...
January 2018: Neurology India
keyword
keyword
50098
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"