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https://www.readbyqxmd.com/read/28641283/-healing-of-amyotrophic-lateral-sclerosis-a-case-report
#1
Inge Mangelsdorf, Harald Walach, Joachim Mutter
BACKGROUND: Amyotrophic lateral sclerosis (ALS) is a devastating disease leading to death within 3-5 years in most cases. New approaches to treating this disease are needed. Here, we report a successful therapy. CASE REPORT: In a 49-year-old male patient suffering from muscle weakness and fasciculations, progressive muscular atrophy, a variant of ALS, was diagnosed after extensive examinations ruling out other diseases. Due to supposed mercury exposure from residual amalgam, the patient's teeth were restored...
June 12, 2017: Complementary Medicine Research
https://www.readbyqxmd.com/read/28630372/multitype-events-and-the-analysis-of-heart-failure-readmissions-illustration-of-a-new-modeling-approach-and-comparison-with-familiar-composite-end-points
#2
Paul M Brown, Justin A Ezekowitz
BACKGROUND: Heart failure-related hospital readmissions and mortality are often outcomes in clinical trials. Patients may experience multiple hospital readmissions over time with mortality acting as a dependent terminal event. Univariate composite end points are used for the analysis of readmissions. We may amend these approaches to include emergency department visits as a further outcome. An alternative multivariate modeling approach that categorizes hospital readmissions and emergency department visits as separate event types is proposed...
June 2017: Circulation. Cardiovascular Quality and Outcomes
https://www.readbyqxmd.com/read/28624940/effect-of-heavy-metals-on-tissue-specific-antioxidant-response-in-indian-major-carps
#3
Debjit Das, Mahammed Moniruzzaman, Adity Sarbajna, Suman Bhusan Chakraborty
Concentrations of heavy metals (Cu, Ni, Zn, Cd and Pb) were measured in sediments, water and liver and kidney tissues of three Indian major carps (Labeo rohita, Catla catla and Cirrhinus cirrhosus), belonging to two different weight groups (250 and 500 g), collected from ponds at two different sites (Nalban bheri and Diamond Harbour). The tissues were analysed for the levels of different antioxidant defence systems such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx), glutathione reductase (GRd), glutathione S-transferase (GST), glutathione (GSH) and malondialdehyde (MDA)...
June 17, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/28622806/graphitic-carbon-nitride-supported-platinum-nanocomposites-for-rapid-and-sensitive-colorimetric-detection-of-mercury-ions
#4
Yi-Wei Wang, Lixing Wang, Fengping An, Hui Xu, Zejin Yin, Shurong Tang, Huang-Hao Yang, Hongbo Song
In this study, graphitic carbon nitride supported platinum nanocomposites (g-C3N4/PtNPs) have been synthesized for the first time by an ultrasonic-assisted chemical reduction method. By using g-C3N4 as the stabilizer, Pt ions could be reduced to PtNPs by NaBH4 and uniformly deposited on the surface of g-C3N4. The resulting g-C3N4/PtNPs exhibited enhanced catalytic activity for the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) compared to that of g-C3N4 or PtNPs alone. After interaction with Hg(2+), the catalytic activity of g-C3N4/PtNPs was effectively inhibited due to the formation of HgPt amalgam...
August 8, 2017: Analytica Chimica Acta
https://www.readbyqxmd.com/read/28621391/trace-determination-of-hg-ii-in-human-saliva-using-disposable-electrochemically-pretreated-graphite-pencil-electrode-surfaces
#5
Abdel-Nasser Kawde
An electrochemically pretreated graphite pencil electrode (PGPE) was designed to assay trace levels of Hg(II) in human saliva. The GPE was pretreated in 0.1 mol/L nitric acid by cycling the potential between -1.6 and -0.6 V for 60 cycles at a scan rate of 50 mV/s. The effects of pretreatment conditions, including media constituents, pH, and various electrochemical techniques and parameters, were analyzed and optimum conditions determined. Square wave anodic stripping voltammetry (SWASV) was used for the determination of Hg(II)...
June 2017: Acta Chimica Slovenica
https://www.readbyqxmd.com/read/28621270/influence-of-hand-instrumentation-and-ultrasonic-scaling-on-the-microleakage-of-various-cervical-restorations-an-in-vitro-study
#6
Bita Rohani, Mehrdad Barekatain, Shirin Z Farhad, Navid Haghayegh
INTRODUCTION: In cervical lesions, various restorative materials can be inserted, which can be affected by the application of periodontal scalers. This study evaluated and compared the marginal seal of class V glass ionomer, composite resin, and amalgam restorations after subjecting them to hand instrumentation and ultrasonic scaling. MATERIALS AND METHODS: In this experimental study, 30 sound human first premolars were selected. In each tooth, buccal and lingual cavities (4 mm mesiodistal width, 3 mm occlusogingival height, and 2 mm depth) were made...
June 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/28620322/the-relationship-of-complex-post-traumatic-stress-disorder-and-post-traumatic-stress-disorder-in-a-culturally-distinct-conflict-affected-population-a-study-among-west-papuan-refugees-displaced-to-papua-new-guinea
#7
Derrick Silove, Alvin Kuowei Tay, Moses Kareth, Susan Rees
BACKGROUND: Controversy continues about the validity of the construct of complex post-traumatic stress disorder (C-PTSD). In particular, questions remain whether C-PTSD can be differentiated from post-traumatic stress disorder (PTSD) and, secondarily, other common mental disorders. The examination of these issues needs to be expanded to populations of diverse cultural backgrounds exposed to prolonged persecution. We undertake such an inquiry among a community sample of West Papuan refugees exposed to extensive persecution and trauma...
2017: Frontiers in Psychiatry
https://www.readbyqxmd.com/read/28620192/luminescent-turn-on-detection-of-hg-ii-via-the-quenching-of-an-iridium-iii-complex-by-hg-ii-mediated-silver-nanoparticles
#8
Jinshui Liu, Kasipandi Vellaisamy, Guanjun Yang, Chung-Hang Leung, Dik-Lung Ma
A novel luminescent turn-on detection method for Hg(II) was developed. The method was based on the silver nanoparticle (AgNP)-mediated quenching of Ir(III) complex 1. The addition of Hg(II) ions causes the luminescence of complex 1 to be recovered due to the oxidation of AgNPs by Hg(II) ions to form Ag(I) and Ag/Hg amalgam. The luminescence intensity of 1 increased in accord with an increased Hg(II) concentration ranging from 0 nM to 180 nM, with the detection limit of 5 nM. This approach offers an innovative method for the quantification of Hg(II)...
June 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28619780/qualitative-analysis-of-6961-free-text-comments-from-the-first-national-cancer-patient-experience-survey-in-scotland
#9
Maggie Cunningham, Mary Wells
OBJECTIVES: To analyse free-text responses from the first Scottish Cancer Patient Experience Survey (SCPES) to understand patients' experiences of care, identify valued aspects and areas for improvement. DESIGN: Inductive thematic analysis of seven free-text comment boxes covering all stages of the cancer experience, from a national cohort survey. SETTING AND PARTICIPANTS: Adult cancer patients diagnosed across all Health Boards in Scotland between July 2013 and March 2014, and who had an inpatient stay or hospital visit between January and September 2014...
June 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/28619518/in-vitro-cytotoxic-potential-of-friedelin-in-human-mcf-7-breast-cancer-cell-regulate-early-expression-of-cdkn2a-and-prb1-neutralize-mdm2-p53-amalgamation-and-functional-stabilization-of-p53
#10
Pandurangan Subash-Babu, David K Li, Ali A Alshatwi
We aimed to explore the cytotoxic and apoptotic effect of friedelin on breast cancer MCF-7 cells. Cytotoxic effect of friedelin on MCF-7 cells was analyzed using MTT, cell and nuclear morphology. The apoptosis mechanism of friedelin on MCF-7 cells was analyzed using real-time PCR. Friedelin potentially inhibit 78% of MCF-7 cell's growth, the IC50 value was 1.8μM in 24h and 1.2μM in 48h. Friedelin increased ROS significantly and DNA damage was confirmed by tunel assay. We found characteristically 52% apoptotic cells and 6% necrotic cells in PI, AO/ErBr staining after 48h treatment with 1...
June 12, 2017: Experimental and Toxicologic Pathology: Official Journal of the Gesellschaft Für Toxikologische Pathologie
https://www.readbyqxmd.com/read/28613830/photocatalysis-based-nanoprobes-using-noble-metal-semiconductor-heterostructure-for-visible-light-driven-in-vivo-detection-of-mercury
#11
Lihua Zhi, Xiaofan Zeng, Hao Wang, Jun Hai, Xiangliang Yang, Baodui Wang, Yanhong Zhu
The development of sensitive and reliable methods to monitor the presence of mercuric ions in cells and organisms is of great importance to biological research and biomedical applications. In this work, we propose a strategy to construct a solar-driven nanoprobe using a 3D Au@MoS2 heterostructure as a photocatalyst and rhodamine B (RhB) as a fluorescent and color change reporter molecule for monitoring Hg2+ in living cells and animals. The sensing mechanism is based on the photoinduced electron formation of gold amalgam in the 3D Au@MoS2 heterostructure under visible light illumination...
June 14, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28612926/the-use-of-silver-amalgam-for-treatment-of-shell-ulcerations-in-turtles-60-cases
#12
F Spadola, M Morici
Shell ulcers were diagnosed based on clinical appearance in 60 turtles. Under general anaesthesia, surgical curettage was performed using a burr mounted on a micro-grinder. A calcium hydroxide paste was applied to the debrided lesions before the application of restorative material. Lesions were completely filled with rapidly hardening silver amalgam. Treated terrapins were hospitalised in dry containers and later were housed in tanks with controlled temperature 24 hours. Fillings were found spontaneously expulsed at various periods after placement...
June 14, 2017: Journal of Small Animal Practice
https://www.readbyqxmd.com/read/28607639/effect-of-diode-laser-irradiation-on-compressive-strength-of-dental-amalgam
#13
Mitra Tabari, Reza Fekrazad, Homayoun Alaghemand, Mahtab Hamzeh
INTRODUCTION: One of the biggest disadvantages of dental amalgam is that gaining its ultimate strength is a slow process. The use of a rapid-setting amalgam with high early compressive strength could be a better option in preventing early fractures in pediatric dentistry. The aim of this study was to determine the effect of diode laser irradiation on compressive strength of dental amalgam. METHODS: A case-control study was performed on 180 amalgam samples made at the Tehran Dental Material Research Center in 2014...
April 2017: Electronic Physician
https://www.readbyqxmd.com/read/28604259/reduced-susceptibility-to-antiseptics-is-conferred-by-heterologous-housekeeping-genes
#14
Supathep Tansirichaiya, Liam J Reynolds, Gianmarco Cristarella, Li Chin Wong, Kimie Rosendahl, Adam P Roberts
Antimicrobial resistance is common in the microbial inhabitants of the human oral cavity. Antimicrobials are commonly encountered by oral microbes as they are present in our diet, both naturally and anthropogenically, and also used in oral healthcare products and amalgam fillings. We aimed to determine the presence of genes in the oral microbiome conferring reduced susceptibility to common antimicrobials. From an Escherichia coli library, 12,277 clones were screened and ten clones with reduced susceptibility to triclosan were identified...
June 12, 2017: Microbial Drug Resistance: MDR: Mechanisms, Epidemiology, and Disease
https://www.readbyqxmd.com/read/28604224/arts-based-palliative-care-training-education-and-staff-development-a-scoping-review
#15
Benjamin Mark Turton, Sion Williams, Christopher R Burton, Lynne Williams
BACKGROUND: The experience of art offers an emerging field in healthcare staff development, much of which is appropriate to the practice of palliative care. The workings of aesthetic learning interventions such as interactive theatre in relation to palliative and end-of-life care staff development programmes are widely uncharted. AIM: To investigate the use of aesthetic learning interventions used in palliative and end-of-life care staff development programmes. DESIGN: Scoping review...
June 1, 2017: Palliative Medicine
https://www.readbyqxmd.com/read/28602850/repair-may-increase-survival-of-direct-posterior-restorations-a-practice-based-study
#16
Luciano Casagrande, Mark Laske, Ewald M Bronkhorst, Marie Charlotte D N J M Huysmans, Niek J M Opdam
OBJECTIVES: To investigate repairs of direct restorations by a group of Dutch general dental practitioners (GDPs) and its consequences on longevity of restorations. METHODS: Data set was based on dental records of patients attending 11 general dental practices (24 Dentists) in the Netherlands. Patients that received Class II Amalgam or Composite restorations were included in the study. The outcomes were considered in two levels: "Success" - When no intervention was necessary on the original restoration, it was considered clinically acceptable...
June 8, 2017: Journal of Dentistry
https://www.readbyqxmd.com/read/28601581/characterization-of-organic-compounds-in-biochars-derived-from-municipal-solid-waste
#17
Sarasadat Taherymoosavi, Vince Verheyen, Paul Munroe, Stephen Joseph, Alicia Reynolds
Municipal solid waste (MSW) generation has been growing in many countries, which has led to numerous environmental problems. Converting MSW into a valuable biochar-based by-product can manage waste and, possibly, improve soil fertility, depending on the soil properties. In this study, MSW-based biochars, collected from domestic waste materials and kerbsides in two Sydney's regions, were composted and pyrolysed at 450°C, 550°C and 650°C. The characteristics of the organic components and their interactions with mineral phases were investigated using a range of analytical techniques, with special attention given to polycyclic aromatic hydrocarbons and heavy metal concentrations...
June 7, 2017: Waste Management
https://www.readbyqxmd.com/read/28588813/severe-dermatitis-might-be-caused-by-a-cross-reaction-between-nickel-and-palladium-and-dental-amalgam-resolved-following-removal-of-dental-restorations
#18
Yoshiro Fujii
This report demonstrates a case of atopic dermatitis that was unresponsive to topical steroid therapy. This clinical report highlights the fact that metals used in dental treatment, such as mercury, as well as cross-reactions between nickel and palladium, may cause systemic hypersensitivity or toxicity.
June 2017: Clinical Case Reports
https://www.readbyqxmd.com/read/28584238/gold-nanozyme-based-paper-chip-for-colorimetric-detection-of-mercury-ions
#19
Kwi Nam Han, Jong-Soon Choi, Joseph Kwon
In this study, we developed a facile gold nanozyme-based paper chip (AuNZ-PAD) for Hg(2+) detection. This device has the advantages of being simple, rapid, cost effective, sensitive, selective, high throughput, and applicable to onsite detection. The colorimetric mercury assay on the AuNZ-PAD is established based on the enzyme-like catalytic activity of gold nanoparticles promoted by the formation of Au-Hg amalgam, which is correlated to the intensity of the colorimetric response resulting from the catalytic reaction of 3,3',5,5'-tetramethylbenzidine (TMB) and H2O2...
June 5, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28583238/regenerative-endodontic-treatment-of-necrotic-primary-molars-with-missing-premolars-a-case-series
#20
Ayca T Ulusoy, Zafer C Cehreli
The endodontic treatment of necrotic primary teeth with missing successors presents a unique clinical challenge. The purpose of this report was to describe the clinical and radiological outcomes of regenerative endodontic treatment (revascularization) of necrotic primary molars. Four infected necrotic primary second molars with missing premolars were treated with a two-visit revascularization protocol. The crowns were restored with amalgam or acid-etch composite resin. The teeth were followed-up clinically and radiographically for 18 months...
May 15, 2017: Pediatric Dentistry
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