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https://www.readbyqxmd.com/read/28446977/endoscopic-management-of-esophageal-leaks
#1
REVIEW
Gabie K B Ong, Richard K Freeman
Traditionally, gold standard treatment for an acute esophageal perforation has been operative repair. Over the past two decades, there has been a paradigm shift towards the use of esophageal stents. Recent advances in biomaterial allowed a new generation of stents to be manufactured that combined (I) a non-permeable covering; (II) radial force sufficient to occlude a transmural esophageal injury and (III) improved ease of removability. The amalgamation of these developments set the stage for utilizing esophageal stents as part of the management algorithm of an acute esophageal perforation...
March 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28446424/hormone-supplementation-for-pubertal-induction-in-girls
#2
REVIEW
Debbie Matthews, Louise Bath, Wolfgang Högler, Avril Mason, Arlene Smyth, Mars Skae
Pubertal induction in girls with ovarian insufficiency aims to mimic normal puberty, a highly complex process. Here we amalgamate the sparse global evidence and propose three options for pubertal induction regimens including oral ethinyloestradiol, and oral and transdermal 17β-oestradiol. The introduction of progestogens is discussed and the transition to hormone supplementation for adult women. The merits and disadvantages of the different options are detailed. The available evidence indicates that transdermal 17β-oestradiol has the most favourable efficacy, safety and cost profile but randomised controlled trials are urgently required to determine which regimen provides the best clinical outcomes...
April 26, 2017: Archives of Disease in Childhood
https://www.readbyqxmd.com/read/28439957/prognostic-indicators-in-pediatric-clinically-isolated-syndrome
#3
Pietro Iaffaldano, Marta Simone, Giuseppe Lucisano, Angelo Ghezzi, Gabriella Coniglio, Vincenzo Brescia Morra, Giuseppe Salemi, Francesco Patti, Alessandra Lugaresi, Guillermo Izquierdo, Roberto Bergamaschi, Jose Antonio Cabrera-Gomez, Carlo Pozzilli, Enrico Millefiorini, Raed Alroughani, Cavit Boz, Eugenio Pucci, Giovanni Bosco Zimatore, Patrizia Sola, Giacomo Lus, Davide Maimone, Carlo Avolio, Eleonora Cocco, Seyed Aidin Sajedi, Gianfranco Costantino, Pierre Duquette, Vahid Shaygannejad, Thor Petersen, Ricardo Fernández Bolaños, Damiano Paolicelli, Carla Tortorella, Tim Spelman, Lucia Margari, Maria Pia Amato, Giancarlo Comi, Helmut Butzkueven, Maria Trojano
OBJECTIVE: To assess prognostic factors for a second clinical attack and a first disability worsening event in pediatric clinically isolated syndrome (pCIS) suggestive of Multiple Sclerosis (MS) patients. METHODS: A cohort of 770 pCIS patients was followed-up for at least 10 years. Cox proportional hazard models and RECursive Partitioning and AMalgamation (RECPAM) tree-regression were used to analyze data. RESULTS: In pCIS, female sex and a multifocal onset were risk factors for a second clinical attack (HR, 95% CI: 1...
April 25, 2017: Annals of Neurology
https://www.readbyqxmd.com/read/28439610/phase-down-of-amalgam-awareness-of-minamata-convention-among-jordanian-dentists
#4
Smj Mortazavi, Ghazal Mortazavi, Maryam Paknahad
[No Abstract Available].
May 2017: Saudi Medical Journal
https://www.readbyqxmd.com/read/28437700/nanomolar-electrochemical-detection-of-caffeic-acid-in-fortified-wine-samples-based-on-gold-palladium-nanoparticles-decorated-graphene-flakes
#5
Kokulnathan Thangavelu, Nehru Raja, Shen-Ming Chen, Wei-Cheng Liao
Amalgamation of noble metal nanomaterials on graphene flakes potentially paves one way to improve their physicochemical properties. This paper deals with the simultaneous electrochemical deposition of gold and palladium nanoparticles on graphene flakes (Au/PdNPs-GRF) for the sensitive determination of caffeic acid (CA). The physiochemical properties of the prepared Au/PdNPs-GRF was characterized by using numerous analytical techniques such as scanning electron microscopy, electron dispersive X-ray spectroscopy, Fourier transform infrared spectroscopy, X-ray powder diffraction, Raman spectroscopy and electrochemical impedance spectroscopy...
April 13, 2017: Journal of Colloid and Interface Science
https://www.readbyqxmd.com/read/28437002/dentists-restorative-decision-making-and-implications-for-an-amalgamless-profession-part-4-clinical-factors
#6
G Alexander, Hopcraft, M J Tyas, R H K Wong
BACKGROUND: The Minamata Convention embodies a world-wide reduction in the production and use of mercury and mercury-containing products and processes, including a phase-down of dental amalgam. This will change the approach to the use of direct restorative materials in the near future. There is little research as to the influence of clinical factors on dentists' decision-making which may be of use when determining the impact of any change. METHODS: An online survey relating to aspects of and attitudes to the use of direct restorative materials was distributed to all dentists who were members of the Australian Dental Association and/or Members or Fellows of the Royal Australasian College of Dental Surgeons...
April 24, 2017: Australian Dental Journal
https://www.readbyqxmd.com/read/28432698/quantitative-evaluation-of-metal-artifacts-using-different-cbct-devices-high-density-materials-and-field-of-views
#7
Marina Codari, Karla de Faria Vasconcelos, Laura Ferreira Pinheiro Nicolielo, Francisco Haiter Neto, Reinhilde Jacobs
OBJECTIVE: To objectively compare the influence of different cone-beam computed tomography (CBCT) devices, high-density materials and field of views (FOVs) on metal artifact expression. MATERIAL AND METHODS: For this in vitro study, three customized acrylic resin phantoms containing high-density materials cylinders: titanium, copper-aluminum alloy and amalgam were scanned on three CBCT devices using high-resolution protocols, same voxel size (0.2 mm) and different FOVs...
April 22, 2017: Clinical Oral Implants Research
https://www.readbyqxmd.com/read/28432002/mir-429-inhibits-metastasis-by-targeting-kiaa0101-in-soft-tissue-sarcoma
#8
Devyani Samantarrai, Bibekanand Mallick
Soft tissue sarcomas (STS) are a heterogeneous group of rare tumors with high metastatic potential. There being only a handful of publication on metastasis of STS, we investigated the miRNA mediated target gene regulations in modulating the metastatic processes in this cancer. In this study, we amalgamated gene and miRNA expression profiles of high-grade STS samples with miRNA target predictions and identified miR-429 targeting KIAA0101 as a novel pair, which remain unexplored in STS metastasis. We validated their expression in metastatic fibrosarcoma cell line, HT1080 and performed several functional assays using miRNA mimics and KIAA0101 over-expression vector to confirm their role in metastasis...
April 18, 2017: Experimental Cell Research
https://www.readbyqxmd.com/read/28430274/high-throughput-and-ultratrace-naked-eye-colorimetric-detection-of-au-3-based-on-the-gold-amalgam-stimulated-peroxidase-mimetic-activity-in-aqueous-solutions
#9
Shouting Zhang, Zhuoyue Zhang, Tiansheng Wang, Dongxu Zhang, Xuemei Li, Zhonghua Xue, Duoliang Shan, Xiaoquan Lu
Herein, we present a catalysis-based, label-free, and efficient strategy for a rapid, high-throughput, highly selective and ultrasensitive naked-eye colorimetric assay of Au(3+) in aqueous solutions, based on the gold amalgam-stimulated peroxidase mimetic activity.
April 21, 2017: Chemical Communications: Chem Comm
https://www.readbyqxmd.com/read/28429974/the-dark-side-of-knowledge-brokering
#10
Roman Kislov, Paul Wilson, Ruth Boaden
Deploying knowledge brokers to bridge the 'gap' between researchers and practitioners continues to be seen as an unquestionable enabler of evidence-based practice and is often endorsed uncritically. We explore the 'dark side' of knowledge brokering, reflecting on its inherent challenges which we categorize as: (1) tensions between different aspects of brokering; (2) tensions between different types and sources of knowledge; and (3) tensions resulting from the 'in-between' position of brokers. As a result of these tensions, individual brokers may struggle to maintain their fragile and ambiguous intermediary position, and some of the knowledge may be lost in the 'in-between world', whereby research evidence is transferred to research users without being mobilized in their day-to-day practice...
April 2017: Journal of Health Services Research & Policy
https://www.readbyqxmd.com/read/28429742/crossing-lines-a-multidisciplinary-framework-for-assessing-connectivity-of-hammerhead-sharks-across-jurisdictional-boundaries
#11
A Chin, C A Simpfendorfer, W T White, G J Johnson, R B McAuley, M R Heupel
Conservation and management of migratory species can be complex and challenging. International agreements such as the Convention on Migratory Species (CMS) provide policy frameworks, but assessments and management can be hampered by lack of data and tractable mechanisms to integrate disparate datasets. An assessment of scalloped (Sphyrna lewini) and great (Sphyrna mokarran) hammerhead population structure and connectivity across northern Australia, Indonesia and Papua New Guinea (PNG) was conducted to inform management responses to CMS and Convention on International Trade in Endangered Species listings of these species...
April 21, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28429633/the-reliability-of-multidimensional-neuropsychological-measures-from-alpha-to-omega
#12
Marley W Watkins
OBJECTIVE: To demonstrate that Coefficient omega, a model-based estimate, is more a more appropriate index of reliability than coefficient alpha for the multidimensional scales that are commonly employed by neuropsychologists. METHOD: As an illustration, a structural model of an overarching general factor and four first-order factors for the WAIS-IV based on the standardization sample of 2200 participants was identified and omega coefficients were subsequently computed for WAIS-IV composite scores...
April 21, 2017: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/28428604/in-vitro-cavity-and-crown-preparations-and-direct-restorations-a-comparison-of-performance-at-the-start-and-end-of-the-fd-programme
#13
F J T Burke, V Ravaghi, L Mackenzie, N Priest, H C Falcon
Aim To assess the performance and thereby the progress of the FDs when they carried out a number of simulated clinical exercises at the start and at the end of their FD year.Methods A standardised simulated clinical restorative dentistry training exercise was carried out by a group of 61 recently qualified dental graduates undertaking a 12 months' duration foundation training programme in England, at both the start and end of the programme. Participants completed a Class II cavity preparation and amalgam restoration, a Class IV composite resin restoration and two preparations for a porcelain-metal full crown...
April 21, 2017: British Dental Journal
https://www.readbyqxmd.com/read/28422598/the-use-of-restorative-materials-in-primary-molars-among-pediatric-dentists-in-israel
#14
Sigalit Blumer, Benjamin Peretz, Tal Ratson
OBJECTIVES: To assess the current choice of various restoration materials among Israeli pediatric dentists according to seniority and specialty. STUDY DESIGN: Participating dentists completed a 23-item questionnaire on their qualifications, type of practice and preference of restorative material. RESULTS: Seventy-five dentists (average age 46.27±12.6 years, 58 females) participated. Forty-one were specialist pediatric dentists and 34 were general practitioners...
2017: Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/28421728/oral-pigmentations-in-physiologic-conditions-post-inflammatory-affections-and-systemic-diseases
#15
Martina Lambertini, Annalisa Patrizi, Giulia M Ravaioli, Emi Dika
Melanocytes are found throughout the oral mucosa but usually go unnoticed because of their relatively low level of pigment production. When focally or generally active in pigment production or proliferation they may be responsible for several affections in the oral mucosae ranging from physiologic pigmentation, systemic diseases to malignant neoplasms. The diagnosis of oral pigmentations (OP) is usually challenging for the physician, but a careful examination of the oral cavity may reveal the first manifestation of underlying systemic diseases...
April 19, 2017: Giornale Italiano di Dermatologia e Venereologia: Organo Ufficiale, Società Italiana di Dermatologia e Sifilografia
https://www.readbyqxmd.com/read/28421104/evolving-tale-of-tcps-new-paradigms-and-old-lacunae
#16
REVIEW
Namrata Dhaka, Vasudha Bhardwaj, Manoj K Sharma, Rita Sharma
Teosinte Branched1/Cycloidea/Proliferating cell factors (TCP) genes are key mediators of genetic innovations underlying morphological novelties, stress adaptation, and evolution of immune response in plants. They have a remarkable ability to integrate and translate diverse endogenous, and environmental signals with high fidelity. Compilation of studies, aimed at elucidating the mechanism of TCP functions, shows that it takes an amalgamation and interplay of several different factors, regulatory processes and pathways, instead of individual components, to achieve the incredible functional diversity and specificity, demonstrated by TCP proteins...
2017: Frontiers in Plant Science
https://www.readbyqxmd.com/read/28418703/radioresistance-of-adenine-to-cosmic-rays
#17
Gabriel S Vignoli Muniz, Christian F Mejía, Rafael Martinez, Basile Auge, Hermann Rothard, Alicja Domaracka, Philippe Boduch
The presence of nucleobases in carbonaceous meteorites on Earth is an indication of the existence of this class of molecules in outer space. However, space is permeated by ionizing radiation, which can have damaging effects on these molecules. Adenine is a purine nucleobase that amalgamates important biomolecules such as DNA, RNA, and ATP. Adenine has a unique importance in biochemistry and therefore life. The aim of this work was to study the effects of cosmic ray analogues on solid adenine and estimate its survival when exposed to corpuscular radiation...
April 2017: Astrobiology
https://www.readbyqxmd.com/read/28412993/paediatric-onset-coronary-artery-anomalies-in-pregnancy-a-single-centre-experience-and-systematic-literature-review
#18
Michelle Keir, Catriona Bhagra, Debra Vatenmakher, Francisca Arancibia-Galilea, Katrijn Jansen, Norihisa Toh, Candice K Silversides, Jack Colman, Samuel C Siu, Mathew Sermer, Andrew M Crean, Rachel M Wald
OBJECTIVES: Individuals with childhood-onset coronary artery anomalies are at increased risk of lifelong complications. Although pregnancy is thought to confer additional risk, a few data are available regarding outcomes in this group of women. We sought to define outcomes of pregnancy in this unique population. METHODS: We performed a retrospective survey of women with paediatric-onset coronary anomalies and pregnancy in our institution, combined with a systematic review of published cases...
April 17, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28412235/evaluation-of-the-efficacy-of-a-metal-artifact-reduction-algorithm-in-different-cone-beam-computed-tomography-scanning-parameters
#19
Polyane Mazucatto Queiroz, Francisco Carlos Groppo, Matheus Lima Oliveira, Francisco Haiter-Neto, Deborah Queiroz Freitas
OBJECTIVE: The aim of this study was to evaluate the efficacy of a metal artifact reduction (MAR) algorithm in cone beam computed tomography (CBCT) images of dental materials obtained with different field-of-view (FOV) and voxel sizes. STUDY DESIGN: Two imaging phantoms were custom-made of acrylic resin. Each phantom had 3 cylinders made of the same dental material: dental amalgam or copper-aluminum alloy. CBCT scans were obtained separately for each of the imaging phantoms using the Picasso-Trio CBCT (Vatech, Hwaseong, Republic of Korea) unit at 4 FOV sizes and 2 voxel sizes...
March 9, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/28411813/voltammetric-determination-of-trace-amounts-of-diacetyl-at-a-mercury-meniscus-modified-silver-solid-amalgam-electrode-following-gas-diffusion-microextraction
#20
Rui M Ramos, Luís M Gonçalves, Vlastimil Vyskočil, José A Rodrigues
A new approach was developed for the determination of trace amounts of diacetyl in food products using gas-diffusion microextraction (GDME) and subsequent detection by differential pulse voltammetry (DPV) at a mercury meniscus modified silver solid amalgam electrode (m-AgSAE). Diacetyl is a vicinal diketone responsible for the buttery aroma in many fermented foods and beverages. Its determination is important not only for evaluation of the final product quality (note of mention: health related concerns were associated with continuous diacetyl exposure) but also to monitor fermentation...
July 1, 2017: Talanta
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