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Measles vaccine

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https://www.readbyqxmd.com/read/29334708/-analysis-of-measles-immunity-level-and-serological-susceptibility-among-yunnan-residents-aged-%C3%A2-20-years
#1
Z X Zhao, R R Zhou, L Q Li, W Yu, Q F Li, P Hu
Objective: To evaluate the population immunity to measles and explore the factors associated with measles susceptibility in Yunnan residents aged ≥20 years. Methods: 2 689 residents aged ≥20 years were selected by multistage stratified systematic randomized sampling in 252 villages of 42 counties in Yunnan Province between June and September in 2015. Each subject was surveyed by the same questionnaire, including general information, measles contained vaccine history, measles history, and 5 ml blood sample of each subject was collected...
January 6, 2018: Zhonghua Yu Fang Yi Xue za Zhi [Chinese Journal of Preventive Medicine]
https://www.readbyqxmd.com/read/29329528/transmission-of-measles-among-healthcare-workers-in-hospital-w-xinjiang-autonomous-region-china-2016
#2
Haimei Jia, Chao Ma, Mengting Lu, Jianping Fu, Lance E Rodewald, Qiru Su, Huaqin Wang, Lixin Hao
BACKGROUND: As China approaches the elimination of measles, outbreaks of measles continue to occur. Healthcare workers (HCWs) are known to be at high risk of infection and transmission of measles virus. A measles outbreak occurred in a hospital in Xinjiang Uighur Autonomous Region of the People's Republic of China. We report an investigation of this outbreak and its implications for measles elimination and outbreak preparedness. METHODS: We conducted a retrospective search for measles cases using hospital records...
January 12, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29327281/effect-of-early-natal-supplementation-of-paracetamol-on-attenuation-of-exotoxin-endotoxin-induced-pyrexia-and-precipitation-of-autistic-like-features-in-albino-rats
#3
Abdulaziz S Saeedan, Indu Singh, Mohd Nazam Ansari, Manjari Singh, Jitendra K Rawat, Uma Devi, Swetlana Gautam, Rajnish K Yadav, Gaurav Kaithwas
The present study was aimed to test the hypothesis that paracetamol (PCM) can precipitate autistic like features when used to counteract vaccine-induced fever using experimental rat pups. The pups were treated with measles mumps rubella (MMR) vaccine, diphtheria tetanus and pertussis (DPT) vaccines and lipopolysaccharide (LPS) with subsequent PCM treatment. The pups were evaluated for postnatal growth (weight gain, eye opening) and behavior alterations (swimming performance, olfactory discrimination, negative geotaxis, nociception, and locomotor activity) by performing battery of neurobehavioral test...
January 11, 2018: Inflammopharmacology
https://www.readbyqxmd.com/read/29325822/parental-vaccine-hesitancy-in-italy-results-from-a-national-survey
#4
Cristina Giambi, Massimo Fabiani, Fortunato D'Ancona, Lorenza Ferrara, Daniel Fiacchini, Tolinda Gallo, Domenico Martinelli, Maria Grazia Pascucci, Rosa Prato, Antonietta Filia, Antonino Bella, Martina Del Manso, Caterina Rizzo, Maria Cristina Rota
In Italy, in 2016, we conducted a cross-sectional survey to estimate vaccine hesitancy and investigate its determinants among parents of children aged 16-36 months. Data on parental attitudes and beliefs about vaccinations were collected through a questionnaire administered online or self-administered at pediatricians' offices and nurseries. Parents were classified as pro-vaccine, vaccine-hesitant or anti-vaccine, according to self-reported tetanus and measles vaccination status of their child. Multivariable logistic regression was used to investigate factors associated with hesitancy...
January 8, 2018: Vaccine
https://www.readbyqxmd.com/read/29325483/characterization-of-vaccination-policies-for-attendance-and-employment-at-day-summer-camps-in-new-york-state
#5
William A Prescott, Kelsey C Violanti, Nicholas M Fusco
INTRODUCTION: New York state requires day/summer camps to keep immunization records for all enrolled campers and strongly recommends requiring vaccination for all campers and staff. The objective of this study was to characterize immunization requirements/recommendations for children/adolescents enrolled in and staff employed at day/summer camps in New York state. METHODS: An electronic hyperlink to a 9-question survey instrument was distributed via e-mail to 178 day/summer camps located in New York state cities with a population size greater than 100 000 people...
January 1, 2018: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29324728/recommendation-of-the-advisory-committee-on-immunization-practices-for-use-of-a-third-dose-of-mumps-virus-containing-vaccine-in-persons-at-increased-risk-for-mumps-during-an-outbreak
#6
Mona Marin, Mariel Marlow, Kelly L Moore, Manisha Patel
A substantial increase in the number of mumps outbreaks and outbreak-associated cases has occurred in the United States since late 2015 (1,2). To address this public health problem, the Advisory Committee on Immunization Practices (ACIP) reviewed the available evidence and determined that a third dose of measles, mumps, rubella (MMR) vaccine is safe and effective at preventing mumps. During its October 2017 meeting, ACIP recommended a third dose of a mumps virus-containing vaccine* for persons previously vaccinated with 2 doses who are identified by public health authorities as being part of a group or population at increased risk for acquiring mumps because of an outbreak...
January 12, 2018: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/29320811/vaccination-policies-requirements-and-exemptions-for-entering-school
#7
Erik Skinner
(1) According to the World Health Organization, immunization prevents between 2 million to 3 million deaths every year across the world. (2) When immunization rates are high, herd immunity develops and limits the spread of the disease, which helps protect those who cannot be vaccinated. (3) Vaccination rates for measles, mumps and rubella vary across the United States, ranging from 85.6 percent in Washington, D.C., to 99.4 percent in Mississippi.
December 2017: NCSL Legisbrief
https://www.readbyqxmd.com/read/29317560/a-new-combined%C3%A2-vaccine%C3%A2-against-measles-mumps-rubella-and-varicella-in-india
#8
Nitin Shah, Raunak Parikh, Giacomo Casabona, Shafi Kolhapure
A quadrivalent MMRV (measles-mumps-rubella-varicella) combination vaccine has recently been launched in India. This vaccine is highly immunogenic, with seroconversion rates against all antigens reaching 96.6-100% at 42 to 56 days after the second vaccine dose in unvaccinated children or in those previously vaccinated with MMR+/-V. Two doses efficacy, against all varicella is 94.1% and effectiveness reaches 91%. The most frequent solicited local adverse event after MMRV vaccine is redness, and fever is the most common solicited general symptom...
December 15, 2017: Indian Pediatrics
https://www.readbyqxmd.com/read/29317117/measles-mumps-and-rubella-antibody-patterns-of-persistence-and-rate-of-decline-following-the-second-dose-of-the-mmr-vaccine
#9
Emma E Seagle, Robert A Bednarczyk, Tenisha Hill, Amy Parker Fiebelkorn, Carole J Hickman, Joseph P Icenogle, Edward A Belongia, Huong Q McLean
BACKGROUND: Antibodies to measles, mumps, and rubella decline 3% per year on average, and have a high degree of individual variation. Yet, individual variations and differences across antigens are not well understood. To better understand potential implications on individual and population susceptibility, we reanalyzed longitudinal data to identify patterns of seropositivity and persistence. METHODS: Children vaccinated with the second dose of measles, mumps, rubella vaccine (MMR2) at 4-6 years of age were followed up to 12 years post-vaccination...
January 6, 2018: Vaccine
https://www.readbyqxmd.com/read/29310585/factors-contributing-to-measles-transmission-during-an-outbreak-in-kamwenge-district-western-uganda-april-to-august-2015
#10
Fred Nsubuga, Lilian Bulage, Immaculate Ampeire, Joseph K B Matovu, Simon Kasasa, Patricia Tanifum, Alex Ario Riolexus, Bao-Ping Zhu
BACKGROUND: In April 2015, Kamwenge District, western Uganda reported a measles outbreak. We investigated the outbreak to identify potential exposures that facilitated measles transmission, assess vaccine effectiveness (VE) and vaccination coverage (VC), and recommend prevention and control measures. METHODS: For this investigation, a probable case was defined as onset of fever and generalized maculopapular rash, plus ≥1 of the following symptoms: Coryza, conjunctivitis, or cough...
January 8, 2018: BMC Infectious Diseases
https://www.readbyqxmd.com/read/29306654/humoral-immune-response-to-measles-and-varicella-vaccination-in-former-very-low-birth-weight-preterm-infants
#11
Carolina Schlindwein Mariano Ferreira, Maria Cristina Abrão Aued Perin, Maria Isabel de Moraes-Pinto, Raquel Maria Simão-Gurge, Ana Lucia Goulart, Lily Yin Weckx, Amélia Miyashiro Nunes Dos Santos
INTRODUCTION: Immune response to vaccination in infants born prematurely may be lower than in infants born at full-term. Some clinical factors might be associated with humoral immune response. OBJECTIVES: The objectives of this study were to compare the immune response to measles and varicella vaccination in infants born prematurely with those born at full-term and to analyze factors associated with measles and varicella antibody levels. METHODS: Prospective study including two groups of infants aged 12 months...
January 4, 2018: Brazilian Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29306505/igg-antibody-prevalence-suggests-high-immunization-needs-in-newcomers-to-luxembourg-2012
#12
Judith M Hübschen, Emilie Charpentier, Pierre Weicherding, Claude P Muller
Vaccine coverage of the general population in Luxembourg is high, but refugees or asylum seekers may be incompletely vaccinated and susceptible to vaccine-preventable diseases. In order to assess protection rates, serum and oral fluid samples were collected from 406 newcomers aged between 13 and 70 years arriving between May and September 2012. Sera were screened for IgG antibodies against measles, rubella, mumps, hepatitis B, tetanus, diphtheria and pertussis. Oral fluid samples were screened for antibodies against measles, mumps and rubella virus to investigate their suitability for antibody prevalence studies...
January 3, 2018: Vaccine
https://www.readbyqxmd.com/read/29300532/measles-outbreak-prevention-and-control-among-adults-lessons-from-an-importation-outbreak-in-yunnan-province-china-2015
#13
Zhixian Zhao, Rongrong Zhou, Wen Yu, Liqun Li, Qiongfen Li, Pei Hu
BACKGROUND: The incidence of measles in Yunnan Province among vaccine target-age children has decreased markedly after attaining and sustaining high 2-dose coverage of measles containing vaccine (MCV) through routine immunization services and supplementary immunization activities (SIAs). Most cases of measles now occur among adults. In 2015, we investigated a measles outbreak among adults to determine transmission patterns and the potential role of nosocomial transmission. METHODS: We enhanced measles surveillance using retrospective active case search...
January 4, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29291222/chickenpox-and-measles-clusters-among-college-students-in-pune-maharashtra
#14
Avinash R Deoshatwar, Vijay P Bondre, Babasaheb V Tandale
Chickenpox and measles, both vaccine preventable febrile rash illnesses, present in a comparatively severe form among young adults/adults than among children. Immunity levels against chickenpox are not known in India and those against measles have been found variable across the country. Places where students or adults/young adults from various parts of the country come together pose a peculiar challenge in preventive policy making regarding these diseases. In this article, we present findings from parallel outbreaks of the two diseases in a graduate/postgraduate institute in the city of Pune...
September 2017: Virusdisease
https://www.readbyqxmd.com/read/29289382/head-to-head-immunogenicity-comparison-of-edmonston-zagreb-vs-aik-c-measles-vaccine-strains-in-infants-aged-8-12-months-a-randomized-clinical-trial
#15
Shahrokh Izadi, Seyed Mohsen Zahraei, Masoud Salehi, Mahdi Mohammadi, Seyed Mehdi Tabatabaei, Talat Mokhtari-Azad
BACKGROUND: A non-inferiority multi-centre parallel randomized double-blind trial was implemented in Zahedan district, Sistan-va-Baluchestan province, Iran, to compare the performance of the two measles vaccines which are in use in the National Immunization Programme of Iran and are of two different measles virus vaccine strains: Edmonston-Zagreb (EZ) strain vs. AIK-C strain. The main outcome measure was appearance of anti-measles antibody in sera. METHODS: 200 infants, 8-12 months old, whose parents consented for their children to be included in the study, were randomized in permutation blocks of size 4-8 in four Urban Health Clinics...
December 27, 2017: Vaccine
https://www.readbyqxmd.com/read/29285631/factors-associated-with-vaccination-status-of-children-aged-12-48-months-in-india-2012-2013
#16
Luke M Shenton, Abram L Wagner, Deepti Bettampadi, Nina B Masters, Bradley F Carlson, Matthew L Boulton
Objectives India has more unvaccinated children than any other country despite provision of free vaccines through the government's Universal Immunization Program. In this study, we calculated the proportion of children aged 12-48 months who were fully vaccinated, under-vaccinated, or who had not received any vaccines. Childhood, household, and sociocultural factors associated with under-vaccination and non-vaccination were evaluated. Methods Using data from India's 4th District-level Health and Facility Survey, 2012-2013 (DLHS-4) and the 2012-2013 Annual Health Survey (AHS), we calculated the proportion of children who were non-vaccinated, under-vaccinated, or fully vaccinated with 1 dose of Bacillus Calmette-Guérin, 3 doses of oral polio vaccine, 3 doses of diphtheria-pertussis-tetanus, and 1 dose of measles-containing vaccine...
December 28, 2017: Maternal and Child Health Journal
https://www.readbyqxmd.com/read/29279450/ten-year-surveillance-of-measles-virus-from-2007-2016-in-osaka-city-japan
#17
Atsushi Kaida, Nobuhiro Iritani, Daiki Kanbayashi, Seiji P Yamamoto, Yuki Hirai, Noritaka Hakui, Ryoko Fujimori, Hiromi Mori, Hidetetsu Hirokawa, Jun Ogasawara, Hideyuki Kubo
  Measles is a highly contagious infection caused by the measles virus (MV). In this study, long-term surveillance was performed in order to survey MV prevalence. A total of 417 patients diagnosed with or suspected of having measles were tested for MV between January 2007 and December 2016 in Osaka City, Japan. Reverse transcription-polymerase chain reaction (RT-PCR)-based testing of clinical specimens showed that 54 patients (12.9%) were MV-positive. An MV epidemic occurred in 2007, in which all detected MV strains were of genotype D5, an epidemic strain in Japan at that time...
December 26, 2017: Japanese Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29278378/modelling-the-transmission-dynamics-and-control-of-mumps-in-mainland-china
#18
Yong Li, Xianning Liu, Lianwen Wang
Mumps is a common childhood viral disease and children have been vaccinated throughout the world since 1967. The incidence of mumps has increased with more than 300,000 young people infected with mumps annually in mainland China since 2005. Therefore, we designed and analyzed long-term mumps surveillance data in an SVEILR (susceptible-vaccinated-exposed-severely infectious-mildly infectious-recovered) dynamic transmission model with optimized parameter values to describe the dynamics of mumps infections in China...
December 26, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29277353/immunologic-non-inferiority-and-safety-of-the-investigational-pneumococcal-non-typeable-haemophilus-influenzae-protein-d-conjugate-vaccine-phid-cv-4-dose-vial-presentation-compared-to-the-licensed-phid-cv-1-dose-vial-presentation-in-infants-a-phase-iii-randomized
#19
Khalequ Zaman, Sheikh Farzana Zaman, Farzana Zaman, Asma Aziz, Sayeed-Bin Faisal, Magali Traskine, Md Ahsan Habib, Javier Ruiz-Guiñazú, Dorota Borys
BACKGROUND: To support vaccination programs in developing countries, a 4-dose vial presentation of pneumococcal non-typeable Haemophilus influenzae protein D-conjugate vaccine (PHiD-CV) was developed. This study assessed immunologic non-inferiority and safety of the investigational PHiD-CV 4-dose versus licensed 1-dose vial presentation in infants. METHODS: In this phase III, mono-center, observer-blind study in Bangladesh, 6-10-week-old infants were randomized 1:1 to receive PHiD-CV primary vaccination (at ages 6, 10, 18 weeks) and a booster dose (at age 9 months) with a 4-dose vial (with preservative, 4DV group) or 1-dose vial (preservative-free, 1DV group)...
December 22, 2017: Vaccine
https://www.readbyqxmd.com/read/29276157/vaccination-coverage-among-school-children-aged-14-15%C3%A2-years-in-the-french-department-of-sarthe
#20
D Huart, S Blanchi
OBJECTIVES: Vaccinations are the main pillar of primary prevention for infectious diseases. To guide and prioritize public health interventions, the Regional Health Agency has asked the Prevention, Vaccination, and Screening Center of the Sarthe department to assess vaccination coverage (VC) at the sub-departmental level. The main objective was to measure the VC among school children aged 14-15 years in Sarthe at the sub-departmental level. PATIENTS AND METHODS: We conducted a VC evaluation survey at the administrative district level among school children aged 14-15 years in the Sarthe department during the first quarter of the 2015-2016 school year...
December 21, 2017: Médecine et Maladies Infectieuses
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