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https://www.readbyqxmd.com/read/28249518/development-of-x-ray-ccd-camera-based-x-ray-micro-ct-system
#1
Partha S Sarkar, N K Ray, Manoj K Pal, Ravi Baribaddala, Ashish Agrawal, Y Kashyap, A Sinha, S C Gadkari
Availability of microfocus X-ray sources and high resolution X-ray area detectors has made it possible for high resolution microtomography studies to be performed outside the purview of synchrotron. In this paper, we present the work towards the use of an external shutter on a high resolution microtomography system using X-ray CCD camera as a detector. During micro computed tomography experiments, the X-ray source is continuously ON and owing to the readout mechanism of the CCD detector electronics, the detector registers photons reaching it during the read-out period too...
February 2017: Review of Scientific Instruments
https://www.readbyqxmd.com/read/28089896/characterization-and-expression-analysis-of-a-chitinase-gene-pmchi-4-from-black-tiger-shrimp-penaeus-monodon-under-pathogen-infection-and-ambient-ammonia-nitrogen-stress
#2
Kaimin Zhou, Falin Zhou, Jianhua Huang, Qibin Yang, Song Jiang, Lihua Qiu, Lishi Yang, Caiyan Zhu, Shigui Jiang
Chitinase is a multi-gene family, which play important physiological roles in crustaceans, involved in several biological processes, including digestion, molting and defense against viruses. In the present study, a chitinase-4 gene (PmChi-4) was cloned from Penaeus monodon by rapid amplification of cDNA ends (RACE). The full length of PmChi-4 cDNA was 2178 bp, including an 1815 bp open reading frame (ORF) which encoded 604 amino acid residues. The predicted PmChi-4 protein was 67.7 kDa and shared 61%-88% identity with the type of Chi-4s from other crustaceans...
January 9, 2017: Fish & Shellfish Immunology
https://www.readbyqxmd.com/read/28078776/performance-of-the-forenseq-tm-dna-signature-prep-kit-on-highly-degraded-samples
#3
Paolo Fattorini, Carlo Previderé, Ilaria Carboni, Giorgio Marrubini, Solange Sorçaburu-Cigliero, Pierangela Grignani, Barbara Bertoglio, Paolo Vatta, Ugo Ricci
Next generation sequencing (NGS) is the emerging technology in forensic genomics laboratories. It offers higher resolution to address most problems of human identification, greater efficiency and potential ability to interrogate very challenging forensic casework samples. In this study, a trial set of DNA samples was artificially degraded by progressive aqueous hydrolysis, and analyzed together with the corresponding unmodified DNA sample and control sample 2800 M, to test the performance and reliability of the ForenSeq(TM) DNA Signature Prep kit using the MiSeq Sequencer (Illumina)...
January 12, 2017: Electrophoresis
https://www.readbyqxmd.com/read/28048775/mo-fg-campus-tep1-04-pseudo-in-vivo-dose-verification-of-a-new-mono-isocentric-technique-for-the-treatment-of-multiple-brain-metastases
#4
E P Pappas, N Papanikolaou, G Kalaitzakis, T Boursianis, D Makris, V Lahanas, I Genitsarios, S Stathakis, L Watts, T Maris, E Pappas
PURPOSE: To validate dose calculation and delivery accuracy of a recently introduced mono-isocentric technique for the treatment of multiple brain metastases in a realistic clinical case. METHODS: Anonymized CT scans of a patient were used to model a hollow phantom that duplicates anatomy of the skull. A 3D printer was used to construct the phantom of a radiologically bone-equivalent material. The hollow phantom was subsequently filled with a polymer gel 3D dosimeter which also acted as a water-equivalent material...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/27986645/cardiopulmonary-resuscitation-training-by-avatars-a-qualitative-study-of-medical-students-experiences-using-a-multiplayer-virtual-world
#5
Johan Creutzfeldt, Leif Hedman, Li Felländer-Tsai
BACKGROUND: Emergency medical practices are often team efforts. Training for various tasks and collaborations may be carried out in virtual environments. Although promising results exist from studies of serious games, little is known about the subjective reactions of learners when using multiplayer virtual world (MVW) training in medicine. OBJECTIVE: The objective of this study was to reach a better understanding of the learners' reactions and experiences when using an MVW for team training of cardiopulmonary resuscitation (CPR)...
December 16, 2016: JMIR Serious Games
https://www.readbyqxmd.com/read/27921069/reaching-200-ps-timing-resolution-in-a-time-of-flight-and-depth-of-interaction-positron-emission-tomography-detector-using-phosphor-coated-crystals-and-high-density-silicon-photomultipliers
#6
Sun Il Kwon, Alessandro Ferri, Alberto Gola, Eric Berg, Claudio Piemonte, Simon R Cherry, Emilie Roncali
Current research in the field of positron emission tomography (PET) focuses on improving the sensitivity of the scanner with thicker detectors, extended axial field-of-view, and time-of-flight (TOF) capability. These create the need for depth-of-interaction (DOI) encoding to correct parallax errors. We have proposed a method to encode DOI using phosphor-coated crystals. Our initial work using photomultiplier tubes (PMTs) demonstrated the possibilities of the proposed method, however, a major limitation of PMTs for this application is poor quantum efficiency in yellow light, corresponding to the wavelengths of the converted light by the phosphor coating...
October 2016: Journal of Medical Imaging
https://www.readbyqxmd.com/read/27917092/colorectal-cancer-screening-navigation-for-the-underserved-experience-of-an-urban-program
#7
Alicia Lamanna, Heather Sheaffer, Carmen Guerra, Michael Kochman
Colorectal cancer is the third leading cause of cancer deaths in the United States. Although colorectal cancer screenings are effective and recommended by all clinical practice guidelines, only 65.7% of adults ages 50 to 75 years are screened. Colorectal cancer screening is disproportionately underutilized in inner city populations. In 2011, the University of Pennsylvania Health System created a navigation program to specifically address poor colorectal cancer screening rates and increase access to colorectal cancer screening colonoscopies for patients in the underserved areas of West, South, and Southwest Philadelphia...
September 2016: Gastroenterology & Hepatology
https://www.readbyqxmd.com/read/27909154/towards-a-novel-modular-architecture-for-cern-radiation-monitoring
#8
Hamza Boukabache, Michel Pangallo, Gael Ducos, Nicola Cardines, Antonio Bellotta, Ciarán Toner, Daniel Perrin, Doris Forkel-Wirth
The European Organization for Nuclear Research (CERN) has the legal obligation to protect the public and the people working on its premises from any unjustified exposure to ionising radiation. In this context, radiation monitoring is one of the main concerns of the Radiation Protection Group. After 30 y of reliable service, the ARea CONtroller (ARCON) system is approaching the end of its lifecycle, which raises the need for new, more efficient radiation monitors with a high level of modularity to ensure better maintainability...
November 30, 2016: Radiation Protection Dosimetry
https://www.readbyqxmd.com/read/27815418/poison-prevention-practices-and-medically-attended-poisoning-in-young-children-multicentre-case-control-study
#9
Denise Kendrick, Gosia Majsak-Newman, Penny Benford, Carol Coupland, Clare Timblin, Mike Hayes, Trudy Goodenough, Adrian Hawkins, Richard Reading
INTRODUCTION: Childhood poisonings are common, placing a substantial burden on health services. Case-control studies have found inconsistent evidence about modifiable risk factors for poisonings among children aged 0-4 years. This study quantifies associations between poison prevention practices and medically attended poisonings in children aged 0-4 years. METHODS: Multicentre case-control study conducted at hospitals, minor injury units and family practices from four study centres in England between 2010 and 2013...
April 2017: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/27804029/development-of-a-tool-to-guide-parents-carrying-a-brca1-2-mutation-share-genetic-results-with-underage-children
#10
Ariane Santerre-Theil, Karine Bouchard, Dominique St-Pierre, Anne-Marie Drolet, Jocelyne Chiquette, Michel Dorval
Although most parents carrying a BRCA1/2 genetic mutation share their test result with their underage children, they report needing support to decide if, when, and how to share risk information and what reactions to expect from their children. We developed a tool to guide parents carrying a BRCA1/2 mutation share their genetic result with underage children. Here, we report on the development of this tool using a qualitative methodology. A tool prototype was developed based on the International Patient Decision Aids Standards Collaboration framework...
November 2, 2016: Journal of Cancer Education: the Official Journal of the American Association for Cancer Education
https://www.readbyqxmd.com/read/27754352/antenatal-clinic-and-stop-smoking-services-staff-views-on-opt-out-referrals-for-smoking-cessation-in-pregnancy-a-framework-analysis
#11
Katarzyna Anna Campbell, Katharine Anna Bowker, Felix Naughton, Melanie Sloan, Sue Cooper, Tim Coleman
Introduction: UK guidance recommends routine exhaled carbon monoxide (CO) screening for pregnant women and "opt-out" referrals to stop smoking services (SSS) of those with CO ≥ 4 ppm. We explored staff views on this referral pathway when implemented in one UK hospital Trust. Methods: Seventeen semi-structured interviews with staff involved in the implementation of the new referral pathway: six antenatal clinic staff (before and after implementation); five SSS staff (after). Data were analyzed using framework analysis...
October 12, 2016: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/27587116/an-online-energy-resolving-beam-profile-detector-for-laser-driven-proton-beams
#12
J Metzkes, K Zeil, S D Kraft, L Karsch, M Sobiella, M Rehwald, L Obst, H-P Schlenvoigt, U Schramm
In this paper, a scintillator-based online beam profile detector for the characterization of laser-driven proton beams is presented. Using a pixelated matrix with varying absorber thicknesses, the proton beam is spatially resolved in two dimensions and simultaneously energy-resolved. A thin plastic scintillator placed behind the absorber and read out by a CCD camera is used as the active detector material. The spatial detector resolution reaches down to ∼4 mm and the detector can resolve proton beam profiles for up to 9 proton threshold energies...
August 2016: Review of Scientific Instruments
https://www.readbyqxmd.com/read/27560852/-just-out-of-reach-on-the-reliability-of-the-action-sentence-compatibility-effect-correction-to-papesh-2015
#13
(no author information available yet)
Reports an error in "Just out of reach: On the reliability of the action-sentence compatibility effect" by Megan H. Papesh (Journal of Experimental Psychology: General, 2015[Dec], Vol 144[6], e116-e141). In the article, the Procedure did not directly state that response options were not visible on the computer screen during Experiments 7 and 8. The first sentence of the Procedure for Experiment 7 should read, “Participants completed a modified button-press version of the experiment described in Experiment 4; unlike Experiment 4, Experiment 7 included no visible on-screen elements apart from the to-be-judged sentences, which came from Glenberg and Kaschak (2002)...
September 2016: Journal of Experimental Psychology. General
https://www.readbyqxmd.com/read/27501885/first-pass-perfusion-imaging-to-improve-the-assessment-of-left-ventricular-thrombus-following-a-myocardial-infarction
#14
Loïc Bière, Martin Audonnet, Guillaume Clerfond, Hermeland Delagarde, Serge Willoteaux, Fabrice Prunier, Alain Furber
PURPOSE: To assess whether a first-pass perfusion sequence (FPP) improved the detection of left ventricular thrombus (LVT). MATERIALS AND METHODS: Three hundred and twenty-nine patients with a first STEMI were prospectively included to undergo cardiac magnetic resonance (CMR) at baseline and after a 3-month follow-up. A CMR delayed analysis was performed by three blinded examiners (2 CMR experts and 1 novice) according to a two-step reading protocol. First, an analysis was performed on cine CMR and late gadolinium enhancement (routine stage)...
September 2016: European Journal of Radiology
https://www.readbyqxmd.com/read/27490546/passive-wireless-hermetic-environment-monitoring-system-for-spray-painting-workshop
#15
Lifeng Wang, Jingjing Ma, Yan Huang, Dan Tang, Qing-An Huang
Passive wireless sensors have the advantages of operating without a power supply and remote sensing capability. Hence, they are very suitable for some harsh environments, such as hermetic environments, rotating parts, or very high temperature environments. The spray painting workshop is such a harsh environment, containing a large amount of flammable paint mist and organic gas. Aiming at this special environment of spray painting workshop, a passive wireless hermetic environment monitoring system was designed, fabricated, and demonstrated...
2016: Sensors
https://www.readbyqxmd.com/read/27456204/the-burden-of-the-variability-introduced-by-the-hep-2-assay-kit-and-the-cad-system-in-ana-indirect-immunofluorescence-test
#16
M Infantino, F Meacci, V Grossi, M Manfredi, M Benucci, M Merone, P Soda
According to the recent recommendations of the American College of Rheumatology, ANA Task Force, IIF technique should be considered the gold standard in antinuclear antibodies (ANAs) testing. To overcome the lack of standardization, biomedical industries have developed several computer-aided diagnosis (CAD) systems. Two hundred and sixty-one consecutive samples with suspected autoimmune diseases were tested for ANA by means of IIF on routinely HEp-2 assay kit (Euroimmun AG). Assignment of result was made if consensus for positive/negative was reached by at least 2 out of 3 expert physicians...
July 25, 2016: Immunologic Research
https://www.readbyqxmd.com/read/27436309/physical-chemical-and-biomolecular-methods-for-the-optimization-of-cationic-lipid-based-lipoplexes-in-vitro-for-the-gene-therapy-applications
#17
Santosh K Misra, Santanu Bhattacharya
Preparation and application protocols play a very important role while optimizing the cationic lipid-based lipoplexes in vitro. These protocols serve as the basis for the betterment of the lipoplexes with regard to their successful application in animals and eventually human subjects. Starting from the chemical structures of used cationic lipids (CLs), optimization of the additive inclusions, methods of nanoparticle (lipoplex) formation, presence of blood serum, time intervals of lipoplex incubation, and type of efficiency read-outs in various conditions play important roles in reaching insightful conclusions...
2016: Methods in Molecular Biology
https://www.readbyqxmd.com/read/27403762/mass-spectrometric-epitope-mapping
#18
Kwabena F M Opuni, Mahmoud Al-Majdoub, Yelena Yefremova, Reham F El-Kased, Cornelia Koy, Michael O Glocker
Mass spectrometric epitope mapping has become a versatile method to precisely determine a soluble antigen's partial structure that directly interacts with an antibody in solution. Typical lengths of investigated antigens have increased up to several 100 amino acids while experimentally determined epitope peptides have decreased in length to on average 10-15 amino acids. Since the early 1990s more and more sophisticated methods have been developed and have forwarded a bouquet of suitable approaches for epitope mapping with immobilized, temporarily immobilized, and free-floating antibodies...
July 12, 2016: Mass Spectrometry Reviews
https://www.readbyqxmd.com/read/27239305/improving-early-childhood-literacy-and-school-readiness-through-reach-out-and-read-ror-program
#19
Kripa Thakur, Sathyanarayan Sudhanthar, Yakov Sigal, Nina Mattarella
Reach out and Read program (ROR) prepares young children to succeed in school by partnering with physicians and training them in handing out age appropriate books and to counsel parents about the importance of reading aloud to their children. Children served by ROR enter kindergarten with stronger vocabulary and language skills. The aim of this project was to improve the rate of distribution of books and physician advice about reading, to the families at each well child visit in the age range of six months to five years...
2016: BMJ Quality Improvement Reports
https://www.readbyqxmd.com/read/27176486/i-hear-you-eat-and-speak-automatic-recognition-of-eating-condition-and-food-type-use-cases-and-impact-on-asr-performance
#20
Simone Hantke, Felix Weninger, Richard Kurle, Fabien Ringeval, Anton Batliner, Amr El-Desoky Mousa, Björn Schuller
We propose a new recognition task in the area of computational paralinguistics: automatic recognition of eating conditions in speech, i. e., whether people are eating while speaking, and what they are eating. To this end, we introduce the audio-visual iHEARu-EAT database featuring 1.6 k utterances of 30 subjects (mean age: 26.1 years, standard deviation: 2.66 years, gender balanced, German speakers), six types of food (Apple, Nectarine, Banana, Haribo Smurfs, Biscuit, and Crisps), and read as well as spontaneous speech, which is made publicly available for research purposes...
2016: PloS One
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