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https://www.readbyqxmd.com/read/28814864/controlled-release-of-lovastatin-from-poly-lactic-co-glycolic-acid-nanoparticles-for-direct-pulp-capping-in-rat-teeth
#1
Hung-Pin Lin, Han-Ping Tu, Yu-Ping Hsieh, Bor-Shiunn Lee
Statin at appropriate concentrations has been shown to induce odontoblastic differentiation, dentinogenesis, and angiogenesis. However, using a carrier to control statin release might reduce toxicity and enhance its therapeutic effects. The aim of this study was to prepare poly(d,l-lactide-co-glycolide acid) (PLGA) nanoparticles that contain lovastatin for application in direct pulp capping. The PLGA-lovastatin particle size was determined using dynamic light scattering measurements and transmission electron microscopy...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28808470/non-surgical-retreatment-of-maxillary-lateral-incisor-with-unusual-anatomy-a-case-report-and-mini-review
#2
Ashraf Shubbar, Behnam Bolhari, Nooshin Fakhari, Parvin Alemi, Ali Nosrat
Knowledge about internal anatomy plays a crucial role in the success of the root canal treatment. Many studies on internal anatomy have repeatedly reported that maxillary lateral incisors have only one canal. The primary aim of this article was to describe successful non-surgical retreatment of a permanent maxillary lateral incisor with two root canals and open apices. The treatment was carried out using dental operating microscope and the canals were obturated with mineral trioxide aggregate (MTA) as an apical plug...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28808469/endodontic-surgery-of-a-symptomatic-overfilled-mta-apical-plug-a-histological-and-clinical-case-report
#3
Saeed Asgary, Sara Fayazi
This case report presents the successful surgical treatment of a symptomatic open apex upper central incisor with a failed overfilled mineral trioxide aggregate (MTA) apical plug. Unintentional overextension of the MTA had occurred two years before the initial visit. An apical lesion adjacent to the excess MTA was radiographically detectable. Endodontic surgery was performed using calcium-enriched mixture (CEM) cement as a root-end filling material. Curettage of the apical lesion showed a mass of unset MTA particles; histopathological examination revealed fragments of MTA and granulation tissues...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28808466/apical-microleakage-in-root-canals-containing-broken-rotary-instruments
#4
Mostafa Godiny, Reza Hatam, Atefeh Khavid, Shahryar Khanlari
INTRODUCTION: Broken instruments in root canals complicate routine endodontic treatment. This study aimed to compare apical microleakage in root canals containing broken rotary instruments filled with mineral trioxide aggregate (MTA), calcium-enriched mixture (CEM) cement, laterally compacted gutta-percha and injected gutta-percha. METHODS AND MATERIALS: In this in vitro, experimental study, 80 extracted human premolars were decoronated and then the roots were randomly divided into four groups (n=20)...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28808465/in-vitro-cytotoxicity-of-guttaflow-bioseal-guttaflow-2-ah-plus-and-mta-fillapex
#5
Gokhan Saygili, Suna Saygili, Ibrahim Tuglu, Ismail Davut Capar
INTRODUCTION: The aim of the present in vitro study was to evaluate the cytotoxicity of different sealers including GuttaFlow Bioseal, GuttaFlow 2, AH-Plus and MTA Fillapex on L929 murine fibroblasts. METHODS AND MATERIALS: Samples of GuttaFlow Bioseal, GuttaFlow 2, AH-Plus and MTA Fillapex were fabricated in Teflon disks of 5 mm diameter and 3 mm thickness. L929 fibroblasts were exposed to the extracts of these materials for 3, 24, 72 and 168 h at 37(°)C with 5% CO2...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28808461/the-effect-of-calcium-chloride-on-push-out-bond-strength-of-calcium-enriched-mixture-cement-and-mineral-trioxide-aggregate
#6
Mohammad Mehdi Shokouhi, Abbas Abbaszadegan, Amin Ameri, Seyed Masih Sharifian, Mohammadreza Nabavizadeh
INTRODUCTION: This in vitro study investigated the effect of adding 10% calcium chloride (CaCl2) on push out bond strength of calcium-enriched mixture (CEM) cement and mineral trioxide aggregate (MTA) to root canal dentin. METHODS AND MATERIALS: A total of 120 root dentin slices with 2 mm thickness were prepared from sixty single-rooted human teeth. Dentinal discs were enlarged to achieve 1.3 mm diameter. The specimens were randomly allocated into eight groups (n=15)...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28808460/the-effect-of-intracanal-medicaments-on-microleakage-of-mineral-trioxide-aggregate-apical-plugs
#7
Mohammadreza Nabavizadeh, Fariborz Moazzami, Mohsen Bahmani, Hossein Mirhadi
INTRODUCTION: The purpose of this in vitro study was to evaluate the effect of calcium hydroxide, double and triple antibiotic paste on the sealing ability of mineral trioxide aggregate (MTA) apical plugs. METHODS AND MATERIALS: A total of 90 extracted teeth with single canals were prepared and randomly divided into four experimental groups (n=20). Intra-canal medicaments were applied for 3 weeks. MTA was placed through the access opening and condensed to the apical area and then fluid filtration technique was utilized to evaluate sealing ability after 1, 7, 14 and 30 days...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28808458/effect-of-propylene-glycol-on-the-sealing-ability-of-mineral-trioxide-aggregate-and-calcium-enriched-mixture-cement-apical-barriers
#8
Alireza Adl, Fereshte Sobhnamayan, Nooshin Sadat Shojaee, Fateme Tahmasebi Azad, Mohsen Bahmani
INTRODUCTION: Propylene glycol (PG) improves the handling, physical, and chemical properties of mineral trioxide aggregate (MTA). This study aimed to evaluate the effect of PG on the sealing ability of MTA and calcium-enriched mixture (CEM) apical barriers. METHODS AND MATERIALS: A total of 70 extracted human maxillary single-rooted teeth were prepared using ProTaper rotary system. The apical 3 mm of the root tips were resected and the root canals were enlarged with Peeso reamers up to #4, to create open apex teeth...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28808457/physicochemical-properties-of-mta-and-portland-cement-after-addition-of-aloe-vera
#9
Alvaro Henrique Borges, Orlando Aguirre Guedes, Luiz Evaristo Ricci Volpato, Gilberto Siebert Filho, Alexandre Meireles Borba, Omar Zina, Evandro Piva, Carlos Estrela
INTRODUCTION: The aim of this in vitro study was to determine the liquid-powder ratio, setting time, solubility, dimensional change, pH, and radiopacity of white structural and non-structural Portland cement, ProRoot MTA and MTA Bio, associated with a 2% glycolic solution containing Aloe Vera, as vehicle. METHODS AND MATERIALS: Five samples of each material were used for each test, according to the American National Standards Institute/American Dental Association (ANSI/ADA) specification No...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28808453/bond-strength-of-white-mineral-trioxide-aggregate-with-and-without-disodium-hydrogen-phosphate-with-different-liquid-to-powder-ratios
#10
Hadi Mokhtari, Sara Jafarizadeh, Hamid Reza Mokhtari Zonouzi, Mehrdad Lotfi, Mohammad Forough Reyhani, Aydin Sohrabi
INTRODUCTION: Mineral trioxide aggregate (MTA) can be used in the treatment of irritated vital pulp and repair of root perforations. However, the initial reaction of inflammatory cells to this material and also its setting time are not ideal. Studies have shown that disodium hydrogen phosphate (DHP), decreases the setting time of MTA, with no effect on its pH. This study was undertaken to evaluate the effect of DHP on push-out bond strength of MTA at different liquid-to-powder ratios...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28808449/efficacy-of-enamel-matrix-derivative-in-vital-pulp-therapy-a-review-of-literature
#11
REVIEW
Shariq Najeeb, Zohaib Khurshid, Muhammad Sohail Zafar, Sana Zohaib, Fahad Siddiqui
INTRODUCTION: Vital pulp therapy (VPT) aims to preserve the health and maintain life of the tooth pulp which has been compromised by caries, trauma or restorative procedures. Recently, enamel matrix derivative (EMD) has been introduced as a material for vital pulp therapy. The aim of this review is to critically analyze and summarize the available literature on EMD for VPT. METHODS AND MATERIALS: Online databases (PubMED/MEDLINE, Google Scholar, ISI Web of Science, and Wiley-Online) were searched by using the following keywords in various combinations: Enamel Matrix Derivative, Emdogain, 'Vital Pulp Therapy, 'Apexogenisis', Apexification, Pulp Capping, Endodontics, Dentine and Pulpotomy for studies indexed from January 1949 to April 2016...
2017: Iranian Endodontic Journal
https://www.readbyqxmd.com/read/28807371/treatment-outcome-following-direct-pulp-capping-using-bioceramic-materials-in-mature-permanent-teeth-with-carious-exposure-a%C3%A2-pilot%C3%A2-retrospective-study
#12
S Linu, M S Lekshmi, V S Varunkumar, V G Sam Joseph
INTRODUCTION: The aim of this study was to investigate the sequelae of direct pulp capping (DPC) using mineral trioxide aggregate (MTA) and Biodentine in mature permanent teeth with carious exposure. METHODS: Clinical records of 30 patients (15 each with MTA and Biodentine) treated with DPC technique from January 2015 to June 2015 were retrieved. Success rates (based on symptoms, sensibility tests, and radiographic analysis) and adverse events were analyzed. RESULTS: The patients were reviewed at 1, 3, 6, 12, and 18 months after treatment...
August 11, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28771386/predictors-of-long-term-risky-driving-behavior-in-the-multimodal-treatment-study-of-children-with-attention-deficit-hyperactivity-disorder
#13
Jessica A Johnson, Ewgeni Jakubovski, Margot O Reed, Michael H Bloch
OBJECTIVE: This study examines predictors of later risky driving behavior in children with attention-deficit/hyperactivity disorder (ADHD). METHODS: Stepwise logistic regression and receiver operating characteristic (ROC) analysis were used to explore baseline predictors of risky driving behavior for adolescents who completed the 8-year follow-up assessment in the Multimodal Treatment Study of Children with Attention-Deficit/Hyperactivity Disorder (MTA). RESULTS: Stepwise logistic regression analysis explained 19% of the total variance in risky driving behavior...
August 3, 2017: Journal of Child and Adolescent Psychopharmacology
https://www.readbyqxmd.com/read/28765825/comparison-of-the-effect-of-prp-prf-and-induced-bleeding-in-the-revascularization-of-teeth-with-necrotic-pulp-and-open-apex-a-triple-blind-randomized-clinical-trial
#14
Vasundara Yayathi Shivashankar, Dexton Antony Johns, Ramesh Kumar Maroli, Mahalaxmi Sekar, Rathinavel Chandrasekaran, Shanmugavel Karthikeyan, Senthil Kumar Renganathan
INTRODUCTION: Treatment of a tooth with necrotic pulp and open apex is a special challenge to the clinicians. Apexification with calcium hydroxide and MTA barrier technique fails to induce continued root maturation which makes the tooth susceptible to root fracture. Hence, an ideal outcome for such a tooth should be regeneration of pulp like tissue into the root canal capable of continuing normal root maturation. AIM: This study aims to compare the effect of Platelet Rich Fibrin (PRF), induced bleeding technique and Platelet Rich Plasma (PRP) in the revascularization of tooth with necrotic pulp and open apex...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28764296/stereomicroscopic-dye-leakage-measurement-of-six-different-root-canal-sealers
#15
Srinidhi V Ballullaya, Vusurumarthi Vinay, Jayaprakash Thumu, Srihari Devalla, Indira Priyadarshini Bollu, Sagarika Balla
INTRODUCTION: Hermetic sealing of the root canal is the most desirable outcome of any root canal treatment, but almost always the filling of the root canal is defective, which is a multifactorial outcome. One such factor majorly influencing the obturation is the root canal sealer used. AIM: The present study was done for evaluating microleakage in different root canal sealers. MATERIALS AND METHODS: Sixty extracted human single rooted teeeth were used in this in-vitro study...
June 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28761141/effects-of-pulpotomy-using-mineral-trioxide-aggregate-on-prostaglandin-transporter-and-receptors-in-rat-molars
#16
Naoto Ohkura, Naoki Edanami, Ryosuke Takeuchi, Aiko Tohma, Mariko Ohkura, Nagako Yoshiba, Kunihiko Yoshiba, Hiroko Ida-Yonemochi, Hayato Ohshima, Takashi Okiji, Yuichiro Noiri
Mineral trioxide aggregate (MTA) is a commonly used dental pulp-capping material with known effects in promoting reparative dentinogenesis. However, the mechanism by which MTA induces dentine repair remains unclear. The aim of the present study was to investigate the role of prostaglandin E2 (PGE2) in dentine repair by examining the localisation and mRNA expression levels of its transporter (Pgt) and two of its receptors (Ep2 and Ep4) in a rat model of pulpotomy with MTA capping. Ep2 expression was detected in odontoblasts, endothelial cells, and nerve fibres in normal and pulpotomised tissues, whereas Pgt and Ep4 were immunolocalised only in the odontoblasts...
July 31, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28751918/cellular-responses-in-human-dental-pulp-stem-cells-treated-with-three-endodontic-materials
#17
Alejandro Victoria-Escandell, José Santiago Ibañez-Cabellos, Sergio Bañuls-Sánchez de Cutanda, Ester Berenguer-Pascual, Jesús Beltrán-García, Eva García-López, Federico V Pallardó, José Luis García-Giménez, Antonio Pallarés-Sabater, Ignacio Zarzosa-López, Manuel Monterde
Human dental pulp stem cells (HDPSCs) are of special relevance in future regenerative dental therapies. Characterizing cytotoxicity and genotoxicity produced by endodontic materials is required to evaluate the potential for regeneration of injured tissues in future strategies combining regenerative and root canal therapies. This study explores the cytotoxicity and genotoxicity mediated by oxidative stress of three endodontic materials that are widely used on HDPSCs: a mineral trioxide aggregate (MTA-Angelus white), an epoxy resin sealant (AH-Plus cement), and an MTA-based cement sealer (MTA-Fillapex)...
2017: Stem Cells International
https://www.readbyqxmd.com/read/28748048/effect-of-different-mixing-methods-on-the-bacterial-microleakage-of-white-portland-cement-and-white-mineral-trioxide-aggregate
#18
Shahriar Shahi, Asmar Bashirzadeh, Hamid Reza Yavari, Farnaz Jafari, Amin Salem Milani, Negin Ghasemi, Mohammad Samiei
Background. of this study was to investigate the effect of different mixing methods (ultrasonic, amalgamator, and conventional) on the bacterial microleakage of white Portland cement (WPC) and white MTA (Tooth-colored Formula, Dentsply, Tulsa Dental, Tulsa, OK). Methods. A hundred human single-rooted permanent teeth were decoronated to obtain 14 mm of root length in all the samples. The root canals were cleaned, shaped and obturated. Three millimeters of each root apex were cut off and randomly divided into 6 groups of 15 each (3 groups for WMTA and 3 groups for WPC, each with 3 different mixing methods) and 2 positive and negative control groups (each containing 5 samples)...
2017: Journal of Dental Research, Dental Clinics, Dental Prospects
https://www.readbyqxmd.com/read/28735788/effect-of-mineral-trioxide-aggregate-apical-plug-thickness-on-fracture-resistance-of-immature-teeth
#19
Ersan Çiçek, Neslihan Yılmaz, M Murat Koçak, Baran Can Sağlam, Sibel Koçak, Burcu Bilgin
INTRODUCTION: The aim of this study was to compare the fracture resistance of simulated immature teeth after using different thicknesses of mineral trioxide aggregate (MTA) apical plugs. METHODS: Fifty-two human maxillary anterior teeth were used. Five teeth were the positive control group; they were prepared using Peeso reamers to simulate immature teeth without any access cavity preparation. Access cavities of the 47 teeth were prepared, and the canals were instrumented with Peeso reamers...
July 20, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/28735787/chemical-physical-properties-and-apatite-forming-ability-of-mineral-trioxide-aggregate-flow
#20
Bruno Martini Guimarães, Rodrigo Ricci Vivan, Bruno Piazza, Murilo Priori Alcalde, Clovis Monteiro Bramante, Marco Antonio Hungaro Duarte
INTRODUCTION: This study aimed to analyze the chemical-physical properties, including pH, volumetric change, radiopacity, and apatite-forming ability in simulated body fluid, of a new tricalcium silicate material (MTA Flow; Ultradent Products Inc, South Jordan, UT). METHODS: MTA Flow was tested in comparison with MTA Angelus (Angelus, Londrina, PR, Brazil). The pH of soaking water was tested up to 168 hours in deionized water. In the solubility test, the root-end fillings of 20 acrylic teeth were scanned twice by micro-computed tomographic imaging before and after immersion in ultrapure water for 168 hours...
July 20, 2017: Journal of Endodontics
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