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https://www.readbyqxmd.com/read/29160804/residual-endodontic-filling-material-after-post-space-preparation-a-confocal-microscopic-study
#1
Yu-Yao Teoh, Laurence J Walsh
This laboratory study assessed removability of endodontic alkaline cements and resin sealers using coronal cross-sectional slices of roots with single canals. Materials were labelled with 0.1% (w/w) sodium fluorescein prior to mixing so that confocal microscopy could be used to quantify material remaining on the walls of post spaces, to assess cleanliness. Roots of extracted teeth were prepared using rotary NiTi instruments then obturated using lateral condensation with gutta percha and epoxy resin sealers (AH-Plus™ or Zirmix™), or were filled by injecting mineral trioxide aggregate (MTA) cement (GC Nex™ MTA or MTAmix™) or a hard-setting calcium hydroxide cement (Supercal™)...
November 21, 2017: Materials
https://www.readbyqxmd.com/read/29153732/reinforcement-of-simulated-immature-permanent-teeth-after-mineral-trioxide-aggregate-apexification
#2
Pairoj Linsuwanont, Sirinya Kulvitit, Busayarat Santiwong
OBJECTIVES: The objectives of this study were to compare the fracture resistance of simulated human immature teeth that have undergone mineral trioxide aggregate (MTA) apexification and have been root-filled with fiber post, composite resin, MTA, or gutta-percha. METHODS: Fifty-six human permanent maxillary incisors were selected. Ten teeth received no treatment (intact teeth group). The root canals of 46 teeth were prepared to an internal diameter of 1.75 mm. Six teeth were used as simulated immature teeth group...
November 15, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29143671/gwas-of-agronomic-traits-in-soybean-collection-included-in-breeding-pool-in-kazakhstan
#3
Alibek Zatybekov, Saule Abugalieva, Svetlana Didorenko, Yelena Gerasimova, Ivan Sidorik, Shynar Anuarbek, Yerlan Turuspekov
BACKGROUND: In recent years soybean is becoming one of the most important oilseed crops in Kazakhstan. Only within the last ten years (2006-2016), the area under soybean is expanded from 45 thousand hectares (ha) in 2006 to 120 thousand ha in 2016. The general trend of soybean expansion is from south-eastern to eastern and northern regions of the country, where average temperatures are lower and growing seasons are shorter. These new soybean growing territories were poorly examined in terms of general effects on productivity level among the diverse sample of soybean accessions...
November 14, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/29143598/gwas-for-plant-growth-stages-and-yield-components-in-spring-wheat-triticum-aestivum-l-harvested-in-three-regions-of-kazakhstan
#4
Yerlan Turuspekov, Aida Baibulatova, Kanat Yermekbayev, Laura Tokhetova, Vladimir Chudinov, Grigoriy Sereda, Martin Ganal, Simon Griffiths, Saule Abugalieva
BACKGROUND: Spring wheat is the largest agricultural crop grown in Kazakhstan with an annual sowing area of 12 million hectares in 2016. Annually, the country harvests around 15 million tons of high quality grain. Despite environmental stress factors it is predicted that the use of new technologies may lead to increases in productivity from current levels of 1.5 to up to 3 tons per hectare. One way of improving wheat productivity is by the application of new genomic oriented approaches in plant breeding projects...
November 14, 2017: BMC Plant Biology
https://www.readbyqxmd.com/read/29130145/late-onset-adhd-understanding-the-evidence-and-building-theoretical-frameworks
#5
REVIEW
Arthur Caye, Margaret H Sibley, James M Swanson, Luis Augusto Rohde
PURPOSE OF REVIEW: The traditional definition of Attention-Deficit/Hyperactivity Disorder (ADHD), assuming onset in childhood, has been challenged by evidence from four recent birth-cohort studies that reported most adults with ADHD lacked a childhood categorical ADHD diagnosis. RECENT FINDINGS: Late onset of symptoms was evaluated in the long-term follow-up of the Multimodal Treatment study of ADHD (MTA). In most cases, other factors were present that discounted the late onset of ADHD symptoms and excluded the diagnosis of ADHD...
November 13, 2017: Current Psychiatry Reports
https://www.readbyqxmd.com/read/29122067/the-clinical-and-radiographic-success-of-primary-molar-pulpotomy-using-biodentine%C3%A2-and-mineral-trioxide-aggregate-a-24-month-randomized-clinical-trial
#6
Mehmet Bani, Nagehan Aktaş, Çağdaş Çınar, Mesut Enes Odabaş
PURPOSE: The purpose of this study was to compare the clinical and radiographic success of Biodentine™ and mineral trioxide aggregate (MTA) pulpotomy in primary molars. METHODS: Thirty-two four- to nine-year-olds were included in this study. The primary molars were randomly assigned to the Biodentine™ and MTA groups. After coronal pulp removal and hemostasis, the remaining pulp tissue was covered with Biodentine™ or MTA. All teeth were restored with stainless steel crowns...
July 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/29114963/potential-utility-of-a-longitudinal-relative-dose-intensity-of-molecularly-targeted-agents-in-phase-1-dose-finding-trials
#7
Akihiro Hirakawa, Kan Yonemori, Fumie Kinoshita, Yumiko Kobayashi, Hitomi S Ohkuma, Asuka Kawachi, Kenji Tamura, Yasuhiro Fujiwara, Larry Rubinstein, Pamela Jo Harris, Naoko Takebe
Phase 1 trials of molecularly targeted agents (MTA) often do not use toxicity data beyond the first cycle of treatment to determine a recommended phase 2 dose (RP2D). We investigated the potential utility of longitudinal relative dose intensity (RDI) that may be a better new way of determining a more accurate RP2D as a lower dose that is presumably more tolerable over the long term without compromising efficacy. All consecutive patients who initially were treated using a single MTA at the conventional RP2D or at one level lower dose (OLLD) of that RP2D in nine phase 1 trials sponsored by the National Cancer Institute were included...
November 8, 2017: Cancer Science
https://www.readbyqxmd.com/read/29111474/the-middle-temporal-artery-surgical-anatomy-and-exposure-for-cerebral-revascularization
#8
Roberto Rodriguez Rubio, Michael T Lawton, Olivia Kola, Halima Tabani, Sonia Yousef, Ali Tayebi Meybodi, Jan-Karl Burkhardt, Ivan El-Sayed, Arnau Benet
BACKGROUND: The middle temporal artery (MTA) is the proximal medial branch of the superficial temporal artery (STA), supplying the temporalis muscle along with deep temporal arteries. Its use in vascularized flaps for reconstructive and otologic procedures has been described, yet its potential use in neurosurgery is not studied. We report a novel technique for exposing the MTA and evaluated its characteristics for extracranial-intracranial (EC-IC) cerebrovascular bypass. METHODS: After a curvilinear frontotemporal incision in 10 cadaveric specimens, the STA was dissected from distal to proximal...
October 27, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29109319/histological-evaluation-of-the-effect-of-platelet-rich-plasma-on-pulp-regeneration-in-nonvital-open-apex-teeth-an-animal-study
#9
Jamileh Ghoddusi, Amir Maghsudlu, Hamid Jafarzadeh, Amirhossein Jafarian, Maryam Forghani
AIM: Platelet-rich plasma (PRP), which is a concentration of growth factors found in platelets, may be a suitable material for pulp regeneration. The aim of this animal study was a histological evaluation of PRP on pulp regeneration in nonvital teeth with immature apices. MATERIALS AND METHODS: A total of 40 premolar dogs' teeth were chosen for this study. After general anesthesia, the teeth were exposed, and subsequently, pulps were removed and the cavities were opened to the oral cavity...
November 1, 2017: Journal of Contemporary Dental Practice
https://www.readbyqxmd.com/read/29104382/clinical-and-radiographic-evaluation-of-four-different-pulpotomy-agents-in-primary-molars-a-longitudinal-study
#10
B Sunitha, Ravindar Puppala, Balaji Kethineni, Manoj K Mallela, Ravigna Peddi, P Tarasingh
Background: The medicament formocresol (FC) used for pulpotomy in primary teeth has great concerns regarding its toxicity due to one of its constituent formaldehyde which acts by tissue fixation. Therefore, new medicaments were introduced which claimed preservation and regeneration of pulp. Aim: The present study is aimed to compare and evaluate the clinical and radiographic success of FC, pulpotec, mineral trioxide aggregate (MTA), and emdogain (EMD) as pulpotomy medicaments in human primary molars...
July 2017: International Journal of Clinical Pediatric Dentistry
https://www.readbyqxmd.com/read/29102078/root-canal-filling-quality-of-a-premixed-calcium-silicate-endodontic-sealer-applied-using-gutta-percha-cone-mediated-ultrasonic-activation
#11
Jung-Ae Kim, Yun-Chan Hwang, Vinicius Rosa, Mi-Kyung Yu, Kwang-Won Lee, Kyung-San Min
INTRODUCTION: The aim of this study was to investigate the filling quality of a recently developed premixed calcium silicate-based endodontic sealer (Endoseal MTA) with a single gutta-percha (GP) cone technique compared with a resin-based sealer (AH plus) with warm vertical compaction. We also explored the effect of GP cone-mediated ultrasonic activation on the filling quality of Endoseal MTA. METHODS: Thirty human single-rooted maxillary premolars with ribbon-shaped canals were prepared and assigned to 3 experimental groups according to filling method: EMS group was Endoseal MTA + single-cone; EMSU group was Endoseal MTA + single-cone with ultrasonic activation; and the APW group was AH plus + warm vertical compaction...
October 25, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29100413/the-pretubulysin-induced-exposure-of-collagen-is-caused-by-endothelial-cell-retraction-that-results-in-an-increased-adhesion-and-decreased-transmigration-of-tumor-cells
#12
Rebecca Schwenk, Tanja Stehning, Iris Bischoff, Angelika Ullrich, Uli Kazmaier, Robert Fürst
Microtubule-targeting agents (MTAs) are the most widely used chemotherapeutic drugs. Pretubulysin (PT), a biosynthetic precursor of the myxobacterial tubulysins, was recently identified as a novel MTA. Besides its strong anti-tumoral activities, PT attenuates tumor angiogenesis, exerts anti-vascular actions on tumor vessels and decreases cancer metastasis formation in vivo. The aim of the present study was to analyze the impact of PT on the interaction of endothelial and tumor cells in vitro to gain insights into the mechanism underlying its anti-metastatic effect...
September 29, 2017: Oncotarget
https://www.readbyqxmd.com/read/29098250/-study-on-clinical-efficacy-and-patients-satisfaction-of-mta-apical-barrier-technique-in-treatment-of-young-permanent-teeth-with-periapical-inflammation
#13
Yuan-Lin Zuo, Chao-Hui Li, Wan-Jie Liu
PURPOSE: To compare the clinical efficacy of MTA apical barrier technique and Vitapex apexification in treatment of young permanent teeth with periapical inflammation, and to evaluate the satisfaction of patients. METHODS: Seventy-five cases of young permanent teeth with periapical inflammation were randomly divided into control group (n=37) and experimental group (n=38). Patients in the control group were treated with Vitapex apexification, while patients in the experimental group were treated with MTA apical barrier technique...
June 2017: Shanghai Kou Qiang Yi Xue, Shanghai Journal of Stomatology
https://www.readbyqxmd.com/read/29090967/the-qualitative-interview-study-of-persistent-and-nonpersistent-substance-use-in-the-mta-sample-characteristics-frequent-use-and-reasons-for-use
#14
James M Swanson, Timothy Wigal, Peter S Jensen, John T Mitchell, Thomas S Weisner, Desiree Murray, L Eugene Arnold, Lily Hechtman, Brooke S G Molina, Elizabeth B Owens, Stephen P Hinshaw, Katherine Belendiuk, Andrea Howard, Sharon B Wigal, Page Sorensen, Annamarie Stehli
OBJECTIVE: To evaluate participants' perceptions about frequent use and reasons for substance use (SU) in the qualitative interview study, an add-on to the multimodal treatment study of ADHD (MTA). METHOD: Using the longitudinal MTA database, 39 ADHD cases and 19 peers with Persistent SU, and 86 ADHD cases and 39 peers without Persistent SU were identified and recruited. In adulthood, an open-ended interview was administered, and SU excerpts were indexed and classified to create subtopics (frequent use and reasons for use of alcohol, marijuana, and other drugs)...
October 1, 2017: Journal of Attention Disorders
https://www.readbyqxmd.com/read/29090391/prevention-of-coronal-discoloration-induced-by-regenerative-endodontic-treatment-in-an-ex-vivo-model
#15
Noushin Shokouhinejad, Mehrfam Khoshkhounejad, Marzieh Alikhasi, Parisa Bagheri, Josette Camilleri
OBJECTIVES: The aim of this study was to assess the effect of sealing the pulp chamber walls with a dentin-bonding agent (DBA) on prevention of discoloration induced by regenerative endodontic procedures (REPs) in an ex vivo model. MATERIALS AND METHODS: Ninety-six bovine incisors were prepared and randomly divided into two groups. In one group, the pulp chamber walls were sealed with DBA before placement of triple antibiotic paste (TAP) containing minocycline inside the root canals, but in the other group, DBA was not applied...
October 31, 2017: Clinical Oral Investigations
https://www.readbyqxmd.com/read/29079052/biocompatibility-of-new-pulp-capping-materials-neomta-plus-mta-repair-hp-and-biodentine-on-human-dental-pulp-stem-cells
#16
Christopher J Tomás-Catalá, Mar Collado-González, David García-Bernal, Ricardo E Oñate-Sánchez, Leopoldo Forner, Carmen Llena, Adrián Lozano, José M Moraleda, Francisco J Rodríguez-Lozano
INTRODUCTION: The aim of the present study was to evaluate the in vitro cytotoxicity of MTA Repair HP, NeoMTA Plus, and Biodentine, new bioactive materials used for dental pulp capping, on human dental pulp stem cells (hDPSCs). METHODS: Biological testing was carried out in vitro on hDPSCs. Cell viability and cell migration assays were performed using eluates of each capping material. To evaluate cell morphology and cell attachment to the different materials, hDPSCs were directly seeded onto the material surfaces and analyzed by scanning electron microscopy...
October 24, 2017: Journal of Endodontics
https://www.readbyqxmd.com/read/29075348/physiochemical-properties-of-experimental-nano-hybrid-mta
#17
V Akhavan Zanjani, K Tabari, S M Sheikh-Al-Eslamian, A N Abrandabadi
Introduction: Development of new pulp capping agents has paved the way towards the preservation of pulp vitality, which is an important goal in restorative dentistry. This study sought to assess the calcium ion release, pH and setting of mineral trioxide aggregate (MTA) Angelus, an experimental formulation of nano-hybrid MTA containing nano-SiO2, nano-Al2O3 and nano-TiO2 and MTA Angelus plus nano-oxides. Methods: In this experimental study, five specimens from each material were placed in polypropylene tubes and immersed in a flask containing deionized distilled water...
July 2017: Journal of Medicine and Life
https://www.readbyqxmd.com/read/29075023/no-clinical-quantifiable-benefits-between-non-surgical-and-surgical-endodontic-treatment
#18
Debra M Ferrailo, Analia Veitz-Keenan
Data sourcesThe authors searched the following electronic databases: the Cochrane Oral Health Trials Register, the Cochrane Central Register of Controlled Trials (CENTRAL), Medline Ovid and Embase Ovid. The US National Registry of Clinical Trials (ClinicalTrials.gov) and the World Health Organisation (WHO) International Clinical Trials Registry Platform were searched for ongoing trials. There were no restrictions regarding language and publication date. The authors hand-searched the reference lists of the studies retrieved and key journals in the field of endodontics...
October 27, 2017: Evidence-based Dentistry
https://www.readbyqxmd.com/read/29070158/partial-pulpotomy-in-immature-permanent-molars-after-carious-exposures-using-different-hemorrhage-control-and-capping-materials
#19
Beste Özgür, Serdar Uysal, H Cem Güngör
PURPOSE: This study compared the outcome of partial pulpotomies with mineral trioxide aggregate (MTA) or calcium hydroxide (CH) following hemorrhage control with 2.5 percent sodium hypochlorite (SH) or 0.9 percent sterile saline (SS) solutions in cariously exposed immature permanent molars. METHODS: Following removal of two to three mm of the pulp at the exposure site, 80 Class I cavities were randomly allocated to four groups according to the hemorrhage control agent and pulp-capping material used: (1) group one-SH plus MTA; (2) group two-SS plus MTA; (3) group three-SH plus CH; (4) group four-SS plus CH...
September 15, 2017: Pediatric Dentistry
https://www.readbyqxmd.com/read/29070150/use-of-vital-pulp-therapies-in-primary-teeth-with-deep-caries-lesions
#20
Vineet Dhar, Abdullah A Marghalani, Yasmi O Crystal, Ashok Kumar, Priyanshi Ritwik, Ozlem Tulunoglu, Laurel Graham
PURPOSE: This manuscript presents evidence-based guidance on the use of vital pulp therapies for treatment of deep caries lesions in children. A guideline panel convened by the American Academy of Pediatric Dentistry formulated evidence-based recommendations on three vital pulp therapies: indirect pulp treatment (IPT; also known as indirect pulp cap), direct pulp cap (DPC), and pulpotomy. METHODS: The basis of the guideline's recommendations was evidence from "Primary Tooth Vital Pulp Therapy: A Systematic Review and Meta-Analysis...
September 15, 2017: Pediatric Dentistry
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