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Pregnancy outcome

Laura E Miller-Graff, Azza H Ahmed, Julia L Paulson
BACKGROUND: Intimate partner violence has been related to breastfeeding difficulties. Few studies, however, have also accounted for other biopsychosocial risk factors associated with women's breastfeeding. Research aim: This study aimed to examine how prenatal intimate partner violence affects women's breastfeeding initiation, early cessation, and exclusivity at 6 weeks postpartum, controlling for perinatal health problems, prenatal depression, childhood adverse experiences, and prenatal breastfeeding education...
June 1, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
Lisa K Akison, Jenny Kuo, Natasha Reid, Roslyn N Boyd, Karen M Moritz
Prenatal alcohol exposure results in cognitive, behavioral and neurological deficits in offspring. There is an urgent need for safe and effective treatments to overcome these effects. Maternal choline supplementation has been identified as a potential intervention. Our objective was to review preclinical and clinical studies using choline supplementation in known cases of fetal alcohol exposure to determine its effectiveness in ameliorating deficits in offspring. A systematic search of six electronic databases was conducted and studies selected by reviewing titles/abstracts against specific inclusion/exclusion criteria...
June 21, 2018: Alcoholism, Clinical and Experimental Research
Ross A Avant, Cameron M Charchenko, Manaf Alom, Mary E Westerman, Francisco Maldonado, Tanner Miest, Landon Trost
Background: To describe self-reported medication patterns and fertility rates in a population of anabolic steroid (AS) users. Methods: We reviewed data from an online survey of AS users and identified a sub-group who had attempted to achieve a pregnancy with their partners while using AS. The online survey consisted of questions addressing demographics, AS use, ancillary medications, and fertility outcomes. Results: A total of 97 men (of 231 total respondents) had attempted to achieve a pregnancy while taking AS and comprise the current cohort...
May 2018: Translational Andrology and Urology
Mary K Samplaski, Chase G Clemesha
Background: The accuracy of online medical information is variable. A 2014 Cochrane review did not support a robust improvement in male infertility after antioxidant supplementation. Many subfertile men take vitamins in hopes of improving their fertility. We sought to evaluate the content of online information for male fertility vitamins, and compare this with the published literature. Methods: We searched Google to assess online information regarding vitamins and male infertility...
May 2018: Translational Andrology and Urology
Zheng Chen, Gang Zhang, Alexander Lerner, An-Hui Wang, Bo Gao, Jie Liu
Background: The roles of clinical etiology and symptoms, imaging findings and biochemical parameters in predicting the prognosis of posterior reversible encephalopathy syndrome (PRES) have not been well-characterized. We perform a meta-analysis of all published studies to assess the value of various risk factors in predicting the prognosis of PRES. Methods: Searches of the PubMed, EMBASE, Cochrane Library, and Web of Science databases were performed to identify the eligible studies...
May 2018: Quantitative Imaging in Medicine and Surgery
Henny Haensgen, Eduardo Albornoz, María C Opazo, Katherinne Bugueño, Evelyn Liliana Jara Fernández, Rebecca Binzberger, Tomás Rivero-Castillo, Luis F Venegas Salas, Felipe Simon, Claudio Cabello-Verrugio, Alvaro A Elorza, Alexis M Kalergis, Susan M Bueno, Claudia A Riedel
Hypothyroxinemia (Hpx) is a thyroid hormone deficiency (THD) condition highly frequent during pregnancy, which although asymptomatic for the mother, it can impair the cognitive function of the offspring. Previous studies have shown that maternal hypothyroidism increases the severity of experimental autoimmune encephalomyelitis (EAE), an autoimmune disease model for multiple sclerosis (MS). Here, we analyzed the immune response after EAE induction in the adult offspring gestated in Hpx. Mice gestated in Hpx showed an early appearance of EAE symptoms and the increase of all parameters of the disease such as: the pathological score, spinal cord demyelination, and immune cell infiltration in comparison to the adult offspring gestated in euthyroidism...
2018: Frontiers in Immunology
Yuki Yoshikawa, Junji Uchida, Chiharu Akazawa, Nobuhiko Suganuma
Purpose: Health-related quality of life (HRQOL) among kidney transplant recipients is associated with physical and psychosocial characteristics. Furthermore, pregnancy and childcare may be particularly challenging for women. The aim of this study was to assess the relationship between patients' psychosocial characteristics and HRQOL, specifically for recipients who have given birth after their kidney transplant. Patients and methods: This was a cross-sectional study...
2018: International Journal of Women's Health
Abram L Wagner, Lu Xia, Aparna Ghosh, Sandip Datta, Priyamvada Pandey, Sujay Santra, Sharmila Chattopadhyay, Uddip Nandi, Tanusree Mazumder, Sucheta Joshi, Joyojeet Pal, Bhramar Mukherjee
BACKGROUND: Community health workers (CHWs) have been placed in many rural areas in India to increase villagers' connections to basic preventive health care. In this study, we describe how pregnant women and mothers of young children react when CHWs inform them that they, or their child, are at high risk of pregnancy-related complications or early childhood developmental delays, and further screening and health care from a physician is recommended. METHODS: In this longitudinal study in rural villages in West Bengal, India, pregnant mothers, as well as mothers of children aged 12-24 months, were screened for high risk complications...
2018: PloS One
Jamille Gregório Dombrowski, Rodrigo Medeiros de Souza, Natércia Regina Mendes Silva, André Barateiro, Sabrina Epiphanio, Lígia Antunes Gonçalves, Claudio Romero Farias Marinho
BACKGROUND: Malaria in pregnancy (MiP) is one of the major causes of mortality and morbidity in tropical regions, causing maternal anemia, intrauterine growth retardation, preterm birth, and low birth weight (LBW). The integration of the information systems on pregnancy and malaria could prove to be a useful method of improved decision making for better maternal-child health. METHODS: A population-based observational study acquired information retrospectively from all live births that occurred between 2006 and 2014 in Cruzeiro do Sul (Acre, Brazil)...
2018: PloS One
Fayiz F El-Shamy, Sanad S El-Kholy, Mahmoud Labib, Ahmed M Kabel
Background and aim Gestational diabetes mellitus (GDM) poses a threat to the mother and child. The aim of this study was to examine the effect of acupressure on the glycemic control and insulin requirement of GDM females. Materials and methods Thirty GDM female patients were randomized to either the study group (SG; n=15), which was treated with acupressure and the standard antenatal care, or the control group (CG; n=15), which was treated with the standard antenatal care. Fasting and 2-h post-prandial blood glucose levels, requirement for insulin and insulin resistance were measured at 24 and 36 weeks' gestation (WG)...
June 21, 2018: Journal of Complementary & Integrative Medicine
Holly P Kennedy, Melissa Cheyney, Hannah G Dahlen, Soo Downe, Maralyn J Foureur, Caroline S E Homer, Elaine Jefford, Alison McFadden, Michaela Michel-Schuldt, Jane Sandall, Hora Soltani, Anna M Speciale, Jennifer Stevens, Saraswathi Vedam, Mary J Renfrew
Despite decades of considerable economic investment in improving the health of families and newborns world-wide, aspirations for maternal and newborn health have yet to be attained in many regions. The global turn toward recognizing the importance of positive experiences of pregnancy, intrapartum and postnatal care, and care in the first weeks of life, while continuing to work to minimize adverse outcomes, signals a critical change in the maternal and newborn health care conversation and research prioritization...
June 21, 2018: Birth
A M Mahesan, S Sadek, V Moussavi, T Vazifedan, A Majeed, T Cunningham, S Oehninger, S Bocca
PURPOSE: The aims of this study were (1) to evaluate clinical outcomes after ICSI cycles using surgically recovered sperm and (2) to assess the influence of maternal age on those outcomes. METHODS: A retrospective cohort study of 24,763 IVF cycles of fresh autologous oocytes and ICSI using surgically recovered sperm reported to the SART CORS database from 2004 to 2015. RESULTS AND CONCLUSIONS: Older women had significantly longer stimulation (p < 0...
June 20, 2018: Journal of Assisted Reproduction and Genetics
Judy E Stern, Chia-Ling Liu, Howard J Cabral, Elliott G Richards, Charles C Coddington, Sunah Hwang, Dmitry Dukhovny, Hafsatou Diop, Stacey A Missmer
PURPOSE: To determine whether differences in birth outcomes among assisted reproductive technology (ART)-treated, subfertile, and fertile women exist in primiparous women with, singleton, vaginal deliveries. METHODS: Society for Assisted Reproductive Technology Clinic Outcome Reporting System (SART CORS) data were linked to Massachusetts vital records and hospital discharges for deliveries between July 2004 and December 2010. Primiparous women with in-state vaginal deliveries, adequate prenatal care, and singleton birth at ≥ 20 weeks (n = 117,779) were classified as ART-treated (linked to ART data from SART CORS, n = 3138); subfertile (not ART-treated but with indicators of subfertility, n = 1507); or fertile (neither ART-treated nor subfertile, n = 113,134)...
June 20, 2018: Journal of Assisted Reproduction and Genetics
Zeynep Tüfekçioğlu, Haşmet Hanağası, Gül Yalçın Çakmaklı, Bülent Elibol, Figen Esmeli Tokuçoğlu, Zeynep Ece Kaya, Sibel Ertan, Sibel Özekmekçi, Murat Emre
INTRODUCTION: Experience about the use and safety of anti-Parkinson (anti-PD) medication during pregnancy is scarce. METHODS: We have retrospectively evaluated the course and outcome of pregnancy in PD patients who used anti-PD medication during their pregnancy. RESULTS: 14 PD patients who used anti-PD medication during part or whole of their pregnancy were included. Dopamine agonists were used in 13 patients, levodopa/benserazide in 4, levodopa/carbidopa/entacapone in 1, rasagiline in 7, amantadine in 4, and biperiden in 1 patient...
June 20, 2018: Journal of Neurology
Jonathan Boss, Jingyi Zhai, Max T Aung, Kelly K Ferguson, Lauren E Johns, Thomas F McElrath, John D Meeker, Bhramar Mukherjee
BACKGROUND: Preterm birth is a significant public health concern and exposure to phthalates has been shown to be associated with an increased odds of preterm birth. Even modest reductions in gestational age at delivery could entail morbid consequences for the neonate and analyzing data with this additional information may be useful. In the present analysis, we consider gestational age at delivery as our outcome of interest and examine associations with multiple phthalates. METHODS: Women were recruited early in pregnancy as part of a prospective, longitudinal birth cohort at the Brigham and Women's Hospital in Boston, Massachusetts...
June 20, 2018: Environmental Health: a Global Access Science Source
Rebecca L Wilson, Alison J Leviton, Shalem Y Leemaqz, Paul H Anderson, Jessica A Grieger, Luke E Grzeskowiak, Petra E Verburg, Lesley McCowan, Gustaaf A Dekker, Tina Bianco-Miotto, Claire T Roberts
BACKGROUND: Pregnant women are at increased susceptibility to vitamin D deficiency. Hence, there is continuing interest in determining how vitamin D influences pregnancy health. We aimed to compare vitamin D status in two distinct populations of pregnant women in Australia and New Zealand and to investigate the relationship between vitamin D status and pregnancy outcome. This included evaluating possible effect measure modifications according to fetal sex. METHODS: Serum 25-hydroxy vitamin D (25(OH)D) was measured at 15 ± 1 weeks' gestation in 2800 women from Adelaide and Auckland who participated in the multi-centre, prospective cohort SCreening fOr Pregnancy Endpoints (SCOPE) study...
June 20, 2018: BMC Pregnancy and Childbirth
Raffael Ott, Jens H Stupin, Andrea Loui, Elisabeth Eilers, Kerstin Melchior, Rebecca C Rancourt, Karen Schellong, Thomas Ziska, Joachim W Dudenhausen, Wolfgang Henrich, Andreas Plagemann
BACKGROUND: Both gestational diabetes mellitus (GDM) as well as overweight/obesity during pregnancy are risk factors for detrimental anthropometric and hormonal neonatal outcomes, identified to 'program' adverse health predispositions later on. While overweight/obesity are major determinants of GDM, independent effects on critical birth outcomes remain unclear. Thus, the aim of the present study was to evaluate, in women with GDM, the relative/independent impact of overweight/obesity vs...
June 20, 2018: BMC Pregnancy and Childbirth
Wondimagegnehu Sisay Woldeyes, Dejene Asefa, Geremew Muleta
BACKGROUND: Investigating cases of severe maternal morbidity (SMM) and severe maternal outcome (SMO) and the quality of maternal health care using near-miss approach has become popular over recent years. The aim of this study was to determine facility based incidence and the determinants of severe maternal outcome (SMO) using this approach. METHODS: Prospective cross-sectional study among all mothers who presented to study facility while pregnant, during child birth and/or within 42 days after termination of pregnancy seeking care and found to have SMM and SMO during the study period was carried out...
June 20, 2018: BMC Pregnancy and Childbirth
Kathleen Szegda, Elizabeth R Bertone-Johnson, Penelope Pekow, Sally Powers, Glenn Markenson, Nancy Dole, Lisa Chasan-Taber
BACKGROUND: Latina women are at increased risk for antenatal depressive disorders, which are common during pregnancy and are associated with elevated risk for poor maternal health and birth outcomes. Physical activity is a potential mechanism to reduce the likelihood of depressive symptoms. The purpose of the study was to assess whether total and domain-specific physical activity in early pregnancy reduced risk for elevated antenatal depressive symptoms in mid-late pregnancy in a population of Latina women at high-risk for depression...
June 20, 2018: BMC Pregnancy and Childbirth
Pedro Brandão, Marília Freixo, Elisa Soares, Catarina Estevinho, Ana Sofia Portela Carvalho, Anabela Melo
Parvovirus B19 has tropism for red line blood cells, causing immune hydrops during pregnancy. A positive anti-Kell Coombs reaction usually happens during pregnancy when there is production of antibodies that target Kell antigens, but cross reactions to other antigens may occur. A 24-year-old Gypsy primigravida, 0 Rhesus positive, presented with persistent isolated hyperthermia for 2 weeks and a positive indirect Coombs test result with anti-Kell antibodies at routine tests. She had a 19-week live fetus. The blood tests revealed bicytopenia with iron deficiency anemia, leucopoenia with neutropenia, and elevated C-reactive protein...
June 20, 2018: Revista Brasileira de Ginecologia e Obstetrícia
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