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https://www.readbyqxmd.com/read/29150862/randomised-crossover-trial-showed-that-using-breast-milk-or-sucrose-provided-the-same-analgesic-effect-in-preterm-infants-of-at-least-28-weeks
#1
L Collados-Gómez, P Ferrera-Camacho, E Fernandez-Serrano, V Camacho-Vicente, C Flores-Herrero, A M García-Pozo, R Jiménez-García
AIM: Repeated, on-going exposure to pain influences the growth, cognitive and motor functions, behaviour, personality and neurodevelopment of preterm infants. We compared the analgesic effects of expressed breast milk and 24% oral sucrose on preterm neonates during venipuncture. METHODS: This multicentre randomised, non-inferiority, cross-over trial focused on five neonatal university units in Madrid, Spain, from October 2013 to October 2014. It comprised 66 preterm infants born at less than 37 weeks and randomly split into two groups...
November 18, 2017: Acta Paediatrica
https://www.readbyqxmd.com/read/29116654/cardiovascular-and-all-cause-mortality-in-patients-with-intermittent-claudication-and-critical-limb-ischaemia
#2
S T W van Haelst, C Koopman, H M den Ruijter, F L Moll, F L Visseren, I Vaartjes, G J de Borst
BACKGROUND: The aim of this study was to evaluate absolute mortality risks and to determine whether changes in mortality risk occurred in patients with intermittent claudication (IC) or critical limb ischaemia (CLI) in the Netherlands between 1998 and 2010. METHODS: Data for patients treated between 1998 and 2010 were obtained from Dutch nationwide registers: the Hospital Discharge Register, Population Register and Cause of Death Register. The registers were used to obtain information regarding IC and CLI hospitalizations, co-morbidities, demographic factors, and date and cause of death...
November 8, 2017: British Journal of Surgery
https://www.readbyqxmd.com/read/29101446/analyzing-the-presentation-and-the-stigma-of-schizophrenia-in-french-newspapers
#3
Dimitrios Lampropoulos, Angelika Wolman, Thémis Apostolidis
PURPOSE: It has been suggested that the stigmatizing presentation of people with schizophrenia by newspapers is an example of structural stigma. In this study, we explore how French newspapers contribute to the stigma of people with schizophrenia. METHODS: All the articles of eight major newspapers (four national and four regional) that include the term schizophr* and that were published in 2015 were therefore analyzed using a coding scheme that we developed inductively...
November 3, 2017: Social Psychiatry and Psychiatric Epidemiology
https://www.readbyqxmd.com/read/29093143/observed-altruism-in-dental-students-an-experiment-using-the-ultimatum-game
#4
Parker A S Crutchfield, Justin S Jarvis, Terry L Olson, Matthew S Wilson
The conventional wisdom in dental and medical education is that dental and medical students experience "ethical erosion" over the duration of dental and medical school. There is some evidence for this claim, but in the case of dental education the evidence consists entirely of survey research, which does not measure behavior. The aim of this study was to measure the altruistic behavior of dental students in order to fill the significant gap in knowledge of how students are disposed to behave, rather than how they are disposed to think...
November 2017: Journal of Dental Education
https://www.readbyqxmd.com/read/29078093/comparison-of-variable-selection-methods-for-high-dimensional-survival-data-with-competing-events
#5
Julia Gilhodes, Christophe Zemmour, Soufiane Ajana, Alejandra Martinez, Jean-Pierre Delord, Eve Leconte, Jean-Marie Boher, Thomas Filleron
BACKGROUND: In the era of personalized medicine, it's primordial to identify gene signatures for each event type in the context of competing risks in order to improve risk stratification and treatment strategy. Until recently, little attention was paid to the performance of high-dimensional selection in deriving molecular signatures in this context. In this paper, we investigate the performance of two selection methods developed in the framework of high-dimensional data and competing risks: Random survival forest and a boosting approach for fitting proportional subdistribution hazards models...
October 20, 2017: Computers in Biology and Medicine
https://www.readbyqxmd.com/read/29049845/impact-of-the-initial-fitness-level-on-the-effects-of-a-structured-exercise-therapy-during-pediatric-stem-cell-transplantation
#6
Susanne Wallek, Anna Senn-Malashonak, Lutz Vogt, Katharina Schmidt, Peter Bader, Winfried Banzer
BACKGROUND: Before and after hematopoietic stem cell transplantation (HSCT), most patients suffer from psychophysical limitations due to the treatment. Exercise interventions demonstrate beneficial effects on, for example, strength, endurance, or health-related quality of life during and after HSCT, but with a great variation among patients concerning the response to exercise. This study examines the influence of the initial fitness on the effects of an exercise therapy in pediatric HSCT...
October 19, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/29048993/personalized-risk-prediction-in-clinical-oncology-research-applications-and-practical-issues-using-survival-trees-and-random-forests
#7
Chen Hu, Jon Arni Steingrimsson
A crucial component of making individualized treatment decisions is to accurately predict each patient's disease risk. In clinical oncology, disease risks are often measured through time-to-event data, such as overall survival and progression/recurrence-free survival, and are often subject to censoring. Risk prediction models based on recursive partitioning methods are becoming increasingly popular largely due to their ability to handle nonlinear relationships, higher-order interactions, and/or high-dimensional covariates...
October 19, 2017: Journal of Biopharmaceutical Statistics
https://www.readbyqxmd.com/read/29044842/changing-perspectives-on-the-strategic-use-of-microwave-heating-in-organic-synthesis
#8
REVIEW
Gregory B Dudley, A E Stiegman
This Personal Account describes collaborative investigations into apocryphal microwave effects in organic chemistry. Focused research on microwave-assisted organic synthesis has been fraught with confusion, controversy, and misinformation. Microwave heating is an undoubtedly useful tactic for organic synthesis, but whether or not it can offer strategic advantages remains an open question in the minds of many people. (Ironically, those who do not consider it an open question are split as to whether it has been resolved affirmatively or negatively...
October 18, 2017: Chemical Record: An Official Publication of the Chemical Society of Japan ... [et Al.]
https://www.readbyqxmd.com/read/29033886/complex-problem-solving-in-teams-the-impact-of-collective-orientation-on-team-process-demands
#9
Vera Hagemann, Annette Kluge
Complex problem solving is challenging and a high-level cognitive process for individuals. When analyzing complex problem solving in teams, an additional, new dimension has to be considered, as teamwork processes increase the requirements already put on individual team members. After introducing an idealized teamwork process model, that complex problem solving teams pass through, and integrating the relevant teamwork skills for interdependently working teams into the model and combining it with the four kinds of team processes (transition, action, interpersonal, and learning processes), the paper demonstrates the importance of fulfilling team process demands for successful complex problem solving within teams...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/29030276/dental-occlusal-surface-supported-titanium-guide-to-assist-cutting-and-drilling-in-mandibular-bilateral-sagittal-split-osteotomy
#10
C Savoldelli, C Vandersteen, O Dassonville, J Santini
INTRODUCTION: Cutting and drilling guides manufactured using computer-aided design/computer-aided manufacturing (CAD/CAM) technologies have attracted increasing interest in orthognathic surgery, particularly in complex cases. The development of these guides requires virtual surgery planning and three-dimensional modelling before they can be printed in titanium, polyamide or resin. We report the use of a personalized titanium device to assist bilateral sagittal split osteotomy (BSSO) with or without genioplasty combined with individual implants for repositioning and fixation...
October 13, 2017: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29027313/patient-experiences-with-care-across-various-types-of-mental-health-care-questionnaire-development-measurement-invariance-and-patients-reports
#11
Luk Bruyneel, Sabine Van Houdt, Ellen Coeckelberghs, Walter Sermeus, Else Tambuyzer, Peter Cosemans, Gert Peeters, Kris Van den Broeck, Ilse Weeghmans, Kris Vanhaecht
To describe the development, validation, and findings of a patient experience questionnaire across 7 types of residential and ambulatory mental health care services. Thirty-five items were hypothesized to cover information, participation, therapeutic relationship, personalized care, organization and collaboration, safety, patient rights, outcomes of care, and discharge preparation and after-care. Also included were 2 overall rating items (scoring and recommending the organization). This Dutch questionnaire was applied in 79 organizations in Belgium (N patients = 5,168)...
October 13, 2017: International Journal of Methods in Psychiatric Research
https://www.readbyqxmd.com/read/29020511/bayesian-additive-decision-trees-of-biomarker-by-treatment-interactions-for-predictive-biomarkers-detection-and-subgroup-identification
#12
Yang Zhao, Wei Zheng, Daisy Y Zhuo, Yuefeng Lu, Xiwen Ma, Hengchang Liu, Zhen Zeng, Glen Laird
Personalized medicine, or tailored therapy, has been an active and important topic in recent medical research. Many methods have been proposed in the literature for predictive biomarkers detection and subgroup identification. In this paper, we propose a novel decision tree based approach applicable in randomized clinical trials. We model the prognostic effects of the biomarkers using additive regression trees and the biomarker-by-treatment effect using a single regression tree. Bayesian approach is utilized to periodically revise the split variables and the split rules of the decision trees, which provides a better overall fitting...
October 11, 2017: Journal of Biopharmaceutical Statistics
https://www.readbyqxmd.com/read/28983874/towards-personal-exposures-how-technology-is-changing-air-pollution-and-health-research
#13
REVIEW
A Larkin, P Hystad
PURPOSE OF REVIEW: We present a review of emerging technologies and how these can transform personal air pollution exposure assessment and subsequent health research. RECENT FINDINGS: Estimating personal air pollution exposures is currently split broadly into methods for modeling exposures for large populations versus measuring exposures for small populations. Air pollution sensors, smartphones, and air pollution models capitalizing on big/new data sources offer tremendous opportunity for unifying these approaches and improving long-term personal exposure prediction at scales needed for population-based research...
December 2017: Current Environmental Health Reports
https://www.readbyqxmd.com/read/28953800/perception-of-body-image-in-early-adolescence-an-investigation-in-secondary-schools
#14
Maria Rosaria Juli
INTRODUCTION: The clinical evidence shows that the onset of eating disorders is increasing in the prepubescent phase or even in childhood. Already starting from the prepubescence the certainties related to the body start to unwind and the individual is encouraged to build new ones, based both on the anatomic transformation of his/her own body and on the social expectation according to the identity. The onset of a Eating Disorders is normally between 13 and 25 years, but in the last years we recorded a lowering in the onset threshold to an age between 11 and 13 years, with some earlier cases at 7 years (Franzoni et al...
September 2017: Psychiatria Danubina
https://www.readbyqxmd.com/read/28944980/failure-mode-and-effects-analysis-a-community-practice-perspective
#15
Bradley W Schuller, Angi Burns, Elizabeth A Ceilley, Alan King, Joan LeTourneau, Alexander Markovic, Lynda Sterkel, Brigid Taplin, Jennifer Wanner, Jeffrey M Albert
PURPOSE: To report our early experiences with failure mode and effects analysis (FMEA) in a community practice setting. METHODS: The FMEA facilitator received extensive training at the AAPM Summer School. Early efforts focused on department education and emphasized the need for process evaluation in the context of high profile radiation therapy accidents. A multidisciplinary team was assembled with representation from each of the major department disciplines. Stereotactic radiosurgery (SRS) was identified as the most appropriate treatment technique for the first FMEA evaluation, as it is largely self-contained and has the potential to produce high impact failure modes...
September 25, 2017: Journal of Applied Clinical Medical Physics
https://www.readbyqxmd.com/read/28931533/inflammatory-potential-of-the-diet-and-colorectal-tumor-risk-in-persons-with-lynch-syndrome
#16
Jesca Gm Brouwer, Maureen Makama, Geertruida J van Woudenbergh, Hans Fa Vasen, Fokko M Nagengast, Jan H Kleibeuker, Ellen Kampman, Fränzel Jb van Duijnhoven
Background: Persons with Lynch syndrome (LS) have high lifetime risk of developing colorectal tumors (CRTs) because of a germline mutation in one of their mismatch repair (MMR) genes. An important process in the development of CRTs is inflammation, which has been shown to be modulated by diet.Objective: We aimed to investigate the association between the inflammatory potential of the diet and the risk of CRTs in persons with LS.Design: We used the dietary intake of 457 persons with LS from a prospective cohort study to calculate the adapted dietary inflammatory index (ADII)...
September 20, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28927468/recent-advances-in-analysis-of-differential-item-functioning-in-health-research-using-the-rasch-model
#17
Curt Hagquist, David Andrich
BACKGROUND: Rasch analysis with a focus on Differential Item Functioning (DIF) is increasingly used for examination of psychometric properties of health outcome measures. To take account of DIF in order to retain precision of measurement, split of DIF-items into separate sample specific items has become a frequently used technique. The purpose of the paper is to present and summarise recent advances of analysis of DIF in a unified methodology. In particular, the paper focuses on the use of analysis of variance (ANOVA) as a method to simultaneously detect uniform and non-uniform DIF, the need to distinguish between real and artificial DIF and the trade-off between reliability and validity...
September 19, 2017: Health and Quality of Life Outcomes
https://www.readbyqxmd.com/read/28917602/comparing-inpatient-versus-outpatient-bowel-preparation-in-children-and-adolescents-undergoing-appendicovesicostomy
#18
David L Weatherly, Konrad M Szymanski, Benjamin M Whittam, William E Bennett, Shelly King, Rosalia Misseri, Martin Kaefer, Richard C Rink, Mark P Cain
PURPOSE: The need for mechanical inpatient bowel preparation (IBP) in reconstructive pediatric urology has come under scrutiny, secondary to literature demonstrating little benefit regarding outcomes. Starting in 2013, a majority of patients undergoing reconstructive procedures at our institution no longer underwent IBP. We hypothesized that outpatient bowel preparation (OBP) would reduce length of stay (LOS) without increasing postoperative complications after appendicovesicostomy surgery...
August 26, 2017: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/28899193/maternal-self-critical-and-dependent-personality-styles-and-mother-infant-communication
#19
Beatrice Beebe, Frank Lachmann
This study investigated mother-infant communication in relation to Blatt's measures of adult personality organization, namely, interpersonal relatedness and self-definition, defining the higher ends of these two measures as dependency and self-criticism, respectively. A nonclinical sample of 126 mother-infant dyads provided the data. An evaluation of maternal self-criticism and dependency was made six weeks postpartum; four months postpartum, mother-infant self- and interactive contingencies during face-to-face play were studied and analyzed in conjunction with the earlier evaluation...
June 2017: Journal of the American Psychoanalytic Association
https://www.readbyqxmd.com/read/28867935/the-history-of-generalized-anxiety-disorder-as-a-diagnostic-category
#20
Marc-Antoine Crocq
From the 19th century into the 20th century, the terms used to diagnose generalized anxiety included "pantophobia" and "anxiety neurosis." Such terms designated paroxysmal manifestations (panic attacks) as well as interparoxysmal phenomenology (the apprehensive mental state). Also, generalized anxiety was considered one of numerous symptoms of neurasthenia, a vaguely defined illness. Generalized anxiety disorder (GAD) appeared as a diagnostic category in the third edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-III) in 1980, when anxiety neurosis was split into GAD and panic disorder...
June 2017: Dialogues in Clinical Neuroscience
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