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https://www.readbyqxmd.com/read/29142938/epidemiological-transition-of-end-stage-kidney-disease-in-oman
#1
Faisal Al Ismaili, Issa Al Salmi, Yaqoub Al Maimani, Abdul Massiah Metry, Humood Al Marhoobi, Alan Hola, Ronald L Pisoni
Introduction: The number of persons receiving renal replacement therapy (RRT) is estimated at more than 2.5 million worldwide, and is growing by 8% annually. Registries in the developing world are not up to standards compared to the United States Renal Data System (USRDS). Herein we examine the causes, progression, and magnitude of end-stage kidney disease (ESKD) over 3 decades in Oman. Methods: We examined ESKD data from 1983 to 2013. Data from 1998 to 2013 were obtained through an Information Management System...
January 2017: KI Reports
https://www.readbyqxmd.com/read/29138235/brip1-overexpression-is-correlated-with-clinical-features-and-survival-outcome-of-luminal-breast-cancer-subtypes
#2
Ishita Gupta, Allal Ouhtit, Adil Al-Ajmi, Syed Gauhar A Rizvi, Hamad Al-Riyami, Marwa Al-Riyami, Yahya Tamimi
In Oman, breast cancer is most common, representing approximately more than 25% of all cancers in women. Relatively younger populations of patients (25 to 40 years) present surprisingly with an aggressive phenotype and advanced tumor stages. In this study, we investigated differential gene expressions in Luminal-A, Luminal-B, Triple negative and Her2+ breast cancer subtypes and compared data to benign tumor samples. We identified a potential candidate gene BRIP1, showing differential expression in the four breast cancer subtypes examined, suggesting that BRIP1 has the profile of a useful diagnostic marker, suitable for targeted therapeutic intervention...
November 14, 2017: Endocrine Connections
https://www.readbyqxmd.com/read/29116906/prevalence-and-determinants-of-burnout-syndrome-and-depression-among-medical-students-at-sultan-qaboos-university-a-cross-sectional-analytical-study-from-oman
#3
Mohammed Al-Alawi, Hamed Al-Sinawi, Ali Al-Qubtan, Jaber Al-Lawati, Assad Al -Habsi, Mohammed Al-Shuraiqi, Samir Al-Adawi, Sathiya Murthi Panchatcharam
This study investigated the prevalence and determinants of Burnout Syndrome and Depressive Symptoms among medical students in Oman. Then, it explored whether the three-dimensional aspects of Burnout Syndrome (High Emotional Exhaustion, High Cynicism and Low Academic Efficacy) would predict the presence of Depressive Symptoms in a logistic regression model. A cross-sectional study was conducted among a random sample of medical students of Sultan Qaboos University. 662 students participated in the study with a response rate of 98%...
November 8, 2017: Archives of Environmental & Occupational Health
https://www.readbyqxmd.com/read/29105283/the-present-and-future-disease-burden-of-hepatitis-c-virus-infections-with-today-s-treatment-paradigm-volume-4
#4
H L Y Chan, C J Chen, O Omede, J Al Qamish, K Al Naamani, A Bane, S S Tan, M Simonova, I Cardenas, M Derbala, O Akin, R O Phillips, M K Abdelmageed, M Abdulla, D Adda, A Al Baqali, N Al Dweik, K Al Ejji, I Al Ghazzawi, S Al Kaabi, M Al Sadadi, J Al Salman, M AlBadri, S A Al-Busafi, H E Al-Romaihi, W Ampofo, K Antonov, C Anyaike, F Arome, S Blach, M M Borodo, S M Brandon, B Bright, M T Butt, D S Chen, P J Chen, R N Chien, W L Chuang, D Cuellar, A A Elbardiny, C Estes, E Farag, J Fung, I Gamkrelidze, V Garcia, J Genov, Z Ghandour, M Ghuloom, B Gomez, J Gunter, J Habeeb, O Hajelssedig, W Hamoudi, S M Himatt, I Hrstic, C C Hu, C F Huang, Y T Hui, R Jahis, D Jelev, A K John, K S Kaliaskarova, Y Kamel, J H Kao, J Khamis, H Khattabi, I Khoudri, A Konysbekova, I Kotzev, M S Lai, W C Lao, J Layden, M H Lee, O Lesi, M Li, A Lo, C K Loo, B Lukšić, A Maaroufi, A O Malu, L Mateva, R Mitova, R Mohamed, M Morović, K Murphy, B Mustapha, A Nersesov, E Ngige, R Njouom, O Njoya, D Nonković, S Obekpa, S Oguche, E E Okolo, C Omuemu, P Ondoa, O Opare-Sem, S Owusu-Ofori, Y N Prokopenko, H Razavi, D Razavi-Shearer, K Razavi-Shearer, B Redae, T Reic, T Rinke de Wit, C Rios, S Robbins, L R Roberts, S J Sanad, J D Schmelzer, M Sharma, T H Su, K Sultan, K Tchernev, O T Y Tsang, S Tsang, C Tzeuton, S Ugoeze, B Uzochukwu, R Vi, A Vince, H U Wani, V W S Wong, A Workneh, R Yacoub, K I Yesmembetov, M Youbi, M F Yuen, H Nde
Factors influencing the morbidity and mortality associated with viremic hepatitis C virus (HCV) infection change over time and place, making it difficult to compare reported estimates. Models were developed for 17 countries (Bahrain, Bulgaria, Cameroon, Colombia, Croatia, Dominican Republic, Ethiopia, Ghana, Hong Kong, Jordan, Kazakhstan, Malaysia, Morocco, Nigeria, Qatar and Taiwan) to quantify and characterize the viremic population as well as forecast the changes in the infected population and the corresponding disease burden from 2015 to 2030...
October 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/29102987/perceived-barriers-to-leisure-time-physical-activity-in-adults-with-type-2-diabetes-attending-primary-healthcare-in-oman-a-cross-sectional-survey
#5
Thamra Alghafri, Saud M Alharthi, Yahya Mohd Al Farsi, Elaine Bannerman, Angela Mary Craigie, Annie S Anderson
OBJECTIVES: Physical activity is fundamental in diabetes management for good metabolic control. This study aimed to identify barriers to performing leisure time physical activity and explore differences based on gender, age, marital status, employment, education, income and perceived stages of change in physical activity in adults with type 2 diabetes in Oman. DESIGN: Cross-sectional study using an Arabic version of the 'Barriers to Being Active' 27-item questionnaire...
November 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/29098145/emerging-and-reemerging-diseases-in-the-world-health-organization-who-eastern-mediterranean-region-progress-challenges-and-who-initiatives
#6
REVIEW
Evans Buliva, Mohamed Elhakim, Nhu Nguyen Tran Minh, Amgad Elkholy, Peter Mala, Abdinasir Abubakar, Sk Md Mamunur Rahman Malik
The Eastern Mediterranean Region (EMR) of the World Health Organization (WHO) continues to be a hotspot for emerging and reemerging infectious diseases and the need to prevent, detect, and respond to any infectious diseases that pose a threat to global health security remains a priority. Many risk factors contribute in the emergence and rapid spread of epidemic diseases in the Region including acute and protracted humanitarian emergencies, resulting in fragile health systems, increased population mobility, rapid urbanization, climate change, weak surveillance and limited laboratory diagnostic capacity, and increased human-animal interaction...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/29084072/school-dropout-and-associated-factors-among-omani-children-with-attention-deficit-hyperactivity-disorder-a-cross-sectional-study
#7
Hassan Mirza, Emmert Roberts, Mohammed Al-Belushi, Humaid Al-Salti, Amira Al-Hosni, Lakshmanan Jeyaseelan, Samir Al-Adawi
OBJECTIVE: Despite the rising incidence of attention-deficit hyperactivity disorder (ADHD), there is a dearth of studies examining the rate of school dropout and its correlates in non-Western populations. METHODS: Medical records were scrutinized to identify Omani children diagnosed with ADHD from 2006 to 2014 in a tertiary care hospital in Oman. The persistence of ADHD symptoms, school performance and dropout, as well as sociodemographic characteristics were examined...
November 1, 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29062564/bacille-calmette-gu%C3%A3-rin-vaccine-induced-tuberculous-hip-osteomyelitis-in-an-infant-case-report
#8
Mohammed S Al-Azri, Jazel Manarang, Yaqoub Al-Mufargi
To this day, tuberculosis (TB) continues to pose a significant global health burden. The World Health Organization's Expanded Programme on Immunization (EPI) recommends the bacille Calmette-Guérin (BCG) vaccine for infants to protect against the haematogenous spread of primary TB and other more severe types of TB infection. We report an eight-month-old boy who presented to the Armed Forces Hospital, Muscat, Oman, in 2015 with a one-month history of intermittent fever associated with a limited range of motion in the right hip area...
August 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29062563/segmental-spinal-muscular-atrophy-localised-to-the-lower-limbs-first-case-from-oman
#9
Roshan Koul, Amna Al-Futaisi, Khalid Al-Thihli, Zandre Bruwer, Patrick Scott
Spinal muscular atrophy (SMA) is a genetic lower motor neuron disease. It usually involves all of the skeletal muscles innervated by the anterior horn cells of the spinal cord. In rare cases, there is also localised involvement of the spinal cord. We report a 10-year-old boy who presented to the Sultan Qaboos University Hospital, Muscat, Oman, in 2015 with muscle weakness restricted to the lower limbs. The presence of a homozygous deletion within the survival of motor neuron 1 gene confirmed the diagnosis of SMA...
August 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29062562/anomalous-origin-of-the-right-coronary-artery-from-the-left-coronary-sinus-case-report
#10
Ziyab K Sarfaraz, Mohammad S Siddiqi, Adil H Al-Kindi, Tarek Alameddine
The anomalous origin of the right coronary artery from the left coronary sinus is a rare congenital disorder and can often result in sudden death upon initial presentation. We report a 19-year-old male patient who was referred to the Sultan Qaboos University Hospital, Muscat, Oman, in 2015 with multiple episodes of exertional angina. He was diagnosed as having an anomalous right coronary artery arising from the left coronary sinus following an intraoperative transesophageal echocardiogram. An unroofing ostioplasty of the anomalous right coronary artery was successful...
August 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29062561/transposition-of-the-great-arteries-and-coarctation-of-the-aorta-in-an-infant-presenting-with-bronchiolitis-an-incidental-finding
#11
Khaloud S Al-Mukhaini, Ala M Mohamed
The transposition of the great arteries (TGA) is a complex congenital heart disease which usually presents as cyanosis in neonates with limited mixing between the systemic and pulmonary circulatory systems. A delayed diagnosis of TGA can lead to ventricular failure. We report a six-week-old infant who was admitted to the paediatric Intensive Care Unit of the Royal Hospital, Muscat, Oman, in 2016 for bronchiolitis. During admission, she was incidentally diagnosed with TGA and coarctation of the aorta. Postnatal screening, including the use of pulse oximetry, plays a significant role in avoiding a late diagnosis of TGA; however, this screening tool is not widely used in Oman...
August 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29062560/use-of-a-minimally-invasive-cardiac-output-monitor-to-optimise-haemodynamics-in-a-patient-with-mitral-valve-disease-undergoing-cerebrovascular-surgery
#12
Ali M Al-Mashani, Niranjan D Waje, Neeraj Salhotra, Samaresh Das, Neelam Suri, Rashid A Al-Sheheimi, Nilay Chatterjee
Patients with mitral valve disease undergoing cerebrovascular surgery face increased inherent risks due to their associated cardiac comorbidities. As such, the anaesthetic management of such patients is distinctly challenging. Simultaneous consideration of both the cerebrovascular and underlying cardiac conditions determines key anaesthetic issues, as fluids and vasopressors or inotropes need to be titrated according to haemodynamic variables in order to optimise cerebral blood flow without compromising cardiac function...
August 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29062559/secondary-adrenal-insufficiency-due-to-the-co-administration-of-ritonavir-and-inhaled-fluticasone-propionate-case-report
#13
Ali Al-Maqbali, Bina Kamble, Salim Al-Qassabi, Ali Elgalib
Ritonavir is a powerful inhibitor of the cytochrome P450 3A4 (CYP3A4) isoenzyme. It is used as a pharmaceutical enhancer in the management of HIV-positive patients. However, when co-administered with other drugs that are metabolised via the CYP3A4 pathway, ritonavir can potentially cause serious drug-drug interactions. Inhaled fluticasone propionate, which is used to treat asthma and chronic obstructive airway disease, is particularly prone to such interactions due to its physiological attributes. We report a HIV-positive 48-year-old male patient who presented to Al Nahdha Hospital, Muscat, Oman, in 2012 with weight loss, generalised weakness and fatigue and diagnosed with secondary adrenal insufficiency as a result of concomitant ritonavir and inhaled fluticasone...
August 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29062558/bilateral-diaphragmatic-paralysis-following-paediatric-cardiac-surgery-experience-of-four-cases-at-the-royal-hospital-muscat-oman
#14
Said A M Al-Hanshi, Mohammed H R Al-Ghafri
Bilateral diaphragmatic paralysis (BDP) is a rare complication of paediatric cardiac surgery. We report four children who developed BDP following cardiac surgery who were managed at the Royal Hospital, Muscat, Oman, between 2009 and 2014. All four children suffered severe respiratory distress soon after extubation and required re-intubation within two hours. In addition, all of the children underwent a tracheostomy as an interim method for ventilation. The four children were successfully weaned from positive pressure ventilation following the functional recovery of at least one side of the diaphragm...
August 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29062557/relationship-between-medication-adherence-and-health-beliefs-among-patients-with-hypertension-in-oman-pilot-study
#15
Huda Al-Noumani, Jia-Rong Wu, Debra Barksdale, Esra Alkhasawneh, George Knafl, Gwen Sherwood
OBJECTIVES: The prevalence of hypertension (HTN) in Oman is alarmingly high and patient adherence to antihypertensive medications is inadequate. This study aimed to assess the relationship between medication adherence and health beliefs among Omani patients with HTN. METHODS: This descriptive cross-sectional pilot study was conducted in December 2015 and included 45 patients with HTN recruited from four primary health centres in Al Dakhiliyah and Muscat governorates, Oman...
August 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29062553/impact-of-educational-activities-in-reducing-pre-analytical-laboratory-errors-a-quality-initiative
#16
Hamed Al-Ghaithi, Anil Pathare, Sahimah Al-Mamari, Rodrigo Villacrucis, Naglaa Fawaz, Salam Alkindi
OBJECTIVES: Pre-analytic errors during diagnostic laboratory investigations can lead to increased patient morbidity and mortality. This study aimed to ascertain the effect of educational nursing activities on the incidence of pre-analytical errors resulting in non-conforming blood samples. METHODS: This study was conducted between January 2008 and December 2015. All specimens received at the Haematology Laboratory of the Sultan Qaboos University Hospital, Muscat, Oman, during this period were prospectively collected and analysed...
August 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29062552/trends-and-outcomes-of-non-small-cell-lung-cancer-in-omani-patients-experience-at-a-university-hospital
#17
Muhammad Furrukh, Shiyam Kumar, Khawaja F Zahid, Hanan S Al-Shamly, Zainab A Al-Jabri, Ikram A Burney, Mansour S Al-Moundhri
OBJECTIVES: The incidence of lung cancer in Oman has shown a gradual but definitive increase since 2002. This study aimed to evaluate the demographic and epidemiological characteristics and survival outcomes of patients with non-small-cell lung cancer (NSCLC) at a university hospital in Oman. METHODS: This study was conducted from January to June 2016. A retrospective analysis was performed of consecutive patients diagnosed with NSCLC presenting to the Sultan Qaboos University Hospital (SQUH) in Muscat, Oman, between March 2000 and December 2015...
August 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29062550/first-cytogenetic-profile-of-omani-patients-with-de-novo-myelodysplastic-syndromes-comparison-with-data-from-asia-africa-europe-and-north-and-south-america
#18
Achandira M Udayakumar, Nagla Fawaz, Anil Pathare, Shakila Asraf, Mohammed Al-Huneini, Khalil Al-Farsi, Salam Al-Kindi, Murtadha Al-Khabouri
Clonal cytogenetic abnormalities have been reported among 30-80% of patients with myelodysplastic syndromes (MDS); however, 20-70% of patients with MDS show a normal karyotype that may nevertheless harbour a cryptic genetic alteration. Earlier reports have suggested that the distribution of specific chromosomal aberrations varies among Western and Asian countries, with geographical and ethnic differences in the frequency of specific chromosomal aberrations. This article compared the cytogenetic data of 36 adult Omani patients with MDS to previously reported data from other populations...
August 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/29055873/ecological-risk-assessment-of-trace-metals-in-the-surface-sediments-of-the-persian-gulf-and-gulf-of-oman-evidence-from-subtropical-estuaries-of-the-iranian-coastal-waters
#19
Moslem Sharifinia, Mohammadreza Taherizadeh, Javid Imanpour Namin, Ehsan Kamrani
This study aimed to investigate the ecological risk assessment of Khamir, Tiyab, and Jagin estuaries and the impact of anthropogenic activities on these ecosystems during a one-year study period (April 2015 to March 2016) using trace metals as pollution indices. The sediment samples were collected from nine sampling stations, following a gradient of contamination from the industrial wastewater and shrimp farming effluents to the less impacted stations. Pollution indices (i.e. PERI and PLI) were applied to ascertain the sediment quality...
October 15, 2017: Chemosphere
https://www.readbyqxmd.com/read/29028812/occurrence-of-the-middle-east-respiratory-syndrome-coronavirus-mers-cov-across-the-gulf-corporation-council-countries-four-years-update
#20
Mahmoud Aly, Mohamed Elrobh, Maha Alzayer, Sameera Aljuhani, Hanan Balkhy
The emergence of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infections has become a global issue of dire concerns. MERS-CoV infections have been identified in many countries all over the world whereas high level occurrences have been documented in the Middle East and Korea. MERS-CoV is mainly spreading across the geographical region of the Middle East, especially in the Arabian Peninsula, while some imported sporadic cases were reported from the Europe, North America, Africa, and lately Asia...
2017: PloS One
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