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https://www.readbyqxmd.com/read/29444506/the-impact-of-advanced-age-on-driving-safety-in-adults-with-medical-conditions
#1
Sanghee Moon, Maud Ranchet, Abiodun Emmanuel Akinwuntan, Mark Tant, David Brian Carr, Mukaila Ajiboye Raji, Hannes Devos
BACKGROUND: Adults aged 85 and older, often referred to as the oldest-old, are the fastest-growing segment of the population. The rapidly increasing number of older adults with chronic and multiple medical conditions poses challenges regarding their driving safety. OBJECTIVE: To investigate the effect of advanced age on driving safety in drivers with medical conditions. METHODS: We categorized 3,425 drivers with preexisting medical conditions into four age groups: middle-aged (55-64 years, n = 1,386), young-old (65-74 years, n = 1,013), old-old (75-84 years, n = 803), or oldest-old (85 years and older, n = 223)...
February 14, 2018: Gerontology
https://www.readbyqxmd.com/read/29444275/e-cigarette-advertising-exposure-explicit-and-implicit-harm-perceptions-and-e-cigarette-use-susceptibility-among-non-smoking-young-adults
#2
Pallav Pokhrel, Thaddeus A Herzog, Pebbles Fagan, Jennifer B Unger, Alan W Stacy
Introduction: This study tested whether exposure to e-cigarette advertising increases e-cigarette use susceptibility among non-smoking young adults by promoting explicit and implicit attitudes towards e-cigarettes as a safer and healthier alternative to combustible cigarettes. Methods: Young adult current non-smokers who had never used an e-cigarette (N = 393; Mean age = 22.1, Standard Deviation = 3.9; 66% Women) were randomly assigned to one of the 3 conditions that involved viewing real-world, print e-cigarette ads...
February 10, 2018: Nicotine & Tobacco Research: Official Journal of the Society for Research on Nicotine and Tobacco
https://www.readbyqxmd.com/read/29444185/humoral-and-cell-mediated-immune-responses-after-a-booster-dose-of-hbv-vaccine-in-hiv-infected-children-adolescents-and-young-adults
#3
Vania Giacomet, Michela Masetti, Pilar Nannini, Federica Forlanini, Mario Clerici, Gian Vincenzo Zuccotti, Daria Trabattoni
OBJECTIVE: HBV vaccine induces protective antibodies only in 23-56% of HIV-infected children. The aim of our study is to evaluate the immunologic effects of a booster dose of HBV vaccine in HIV-infected youth. DESIGN: 53 young HIV-infected patients in whom HBV vaccination did not elicit protective Ab titers were enrolled. All patients were on ART with optimal immunological and viral response. METHOD: All patients received a booster dose of HBV vaccine (HBVAXPRO 10 μg i...
2018: PloS One
https://www.readbyqxmd.com/read/29444116/field-evaluation-of-the-safety-acceptability-and-feasibility-of-early-infant-male-circumcision-using-the-accucirc-device
#4
Robert C Bailey, Irene Nyaboke, Mary Ellen Mackesy-Amiti, Erick Okello, Valentine Pengo, Betha Ochomo, Mary Emmaculate Auma, Simon Were, Stella Ojuok, Evelyne Adoyo, Mildred Adhiambo, Marisa R Young, Rebeca M Plank, Fredrick O Otieno
BACKGROUND: As countries scale up adult voluntary medical male circumcision (VMMC) for HIV prevention, they are looking ahead to long term sustainable strategies, including introduction of early infant male circumcision (EIMC). Although a number of devices for EIMC are prequalified by the World Health Organization, evaluation of additional devices can provide policy-makers and clinicians the information required to make informed decisions. We undertook a field evaluation of the safety and acceptability of the AccuCirc device in Kisumu County, Kenya...
2018: PloS One
https://www.readbyqxmd.com/read/29442287/recent-developments-in-adolescent-and-young-adult-aya-acute-lymphoblastic-leukemia
#5
REVIEW
Victor M Orellana-Noia, Michael G Douvas
PURPOSE OF REVIEW: Adolescent and Young Adult (AYA) Oncology is a relatively new field encompassing research in the unique pathophysiology, clinical care, and psychosocial issues facing patients between the ages of 15 and 40 with cancer. About 100,000 of the approximately 1.5 million people diagnosed annually with cancer in the USA are in this age range. This chapter will review notable new developments in the care of adolescents and young adults with acute lymphoblastic leukemia (ALL) within the last 3 years...
February 14, 2018: Current Hematologic Malignancy Reports
https://www.readbyqxmd.com/read/29442197/a-lack-of-aquatic-rescue-competency-a-drowning-risk-factor-for-young-adults-involved-in-aquatic-emergencies
#6
Lauren A Petrass, Jennifer D Blitvich
Drowning is an important public health issue with major impacts on young adults aged 15-24 years, yet little is known about the causal factors for drowning for this group. As young adults recreate with peers in unpatrolled aquatic environments, the capacity to perform effective and efficient rescues seems pivotal. This study examined perceived ability of young adults to perform a rescue; determined the level of aquatic rescue knowledge; and measured the effect of an aquatic rescue intervention. In total, 135 participants completed pre- and post-intervention surveys and rescue practical testing...
February 13, 2018: Journal of Community Health
https://www.readbyqxmd.com/read/29441737/cesium-137-contaminated-roads-and-health-problems-in-residents-an-epidemiological-investigation-in-seoul-2011
#7
Mina Ha, Young Su Ju, Won Jin Lee, Seung Sik Hwang, Sang Chul Yoo, Kyung Hwa Choi, Eunae Burm, Jieon Lee, Yun Keun Lee, Sanghyuk Im
BACKGROUND: In 2011, two roads in a residential area in Seoul were found to be contaminated with the radionuclide cesium-137 (137Cs). In response to public concerns, an epidemiological study was conducted. METHODS: The standardized cancer incidence ratios in the affected and neighboring regions were calculated based on the central cancer registry. Households in the region were sampled using the random stratified sampling technique, and questionnaires were administered to family members, via home visit and via students in elementary to high schools...
February 26, 2018: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/29441720/identification-and-characterization-of-homeobox-hox-genes-and-conservation-of-the-single-hox-cluster-324-6%C3%A2-kb-in-the-water-flea-daphnia-magna
#8
Duck-Hyun Kim, Bo-Young Lee, Hui-Su Kim, Chang-Bum Jeong, Dae-Sik Hwang, Il-Chan Kim, Jae-Seong Lee
We report the complete sequence analysis of the entire complement of eight typical homeobox (Hox) genes (Lab, Pb, Dfd, Scr, Antp, Ubx, Abd-A, and Abd-B) and two other genes (Hox3 and Ftz) in a 324.6-kb region in the water flea Daphnia magna. In the cluster of D. magna Hox genes, we found one long interspersed nuclear element (LINE)/R2-NeSL between Ubx and Abd-A that was not present in Daphnia pulex Hox genes. In basal expression of Hox genes at different developmental stages, biothorax complex genes (Ubx, Abd-A, and Abd-B) and some antennapedia complex genes (Lab, Scr, Antp) were moderately expressed, but the Hox3 gene was barely expressed...
February 14, 2018: Journal of Experimental Zoology. Part B, Molecular and Developmental Evolution
https://www.readbyqxmd.com/read/29441653/cognitive-control-under-stressful-conditions-in-transitional-age-youth-with-bipolar-disorder-diagnostic-and-sleep-related-differences-in-fronto-limbic-activation-patterns
#9
Adriane M Soehner, Tina R Goldstein, Sarah M Gratzmiller, Mary L Phillips, Peter L Franzen
OBJECTIVES: Adults with bipolar disorder (BD) display aberrant activation in fronto-limbic neural circuitry during cognitive control. However, fronto-limbic response to cognitive control, and factors destabilizing this circuitry, remain under-studied during the transition from adolescence to young adulthood in BD. Sleep patterns are disturbed in BD, undergo change in adolescence, and support brain function. Among transitional age youth, BD diagnosis and sleep (duration and variability) were tested as predictors of fronto-limbic response to a stressful cognitive control task...
February 13, 2018: Bipolar Disorders
https://www.readbyqxmd.com/read/29441411/interrater-variability-in-asa-physical-status-assignment-an-analysis-in-the-pediatric-cancer-setting
#10
Luis E Tollinche, Gloria Yang, Kay-See Tan, Ruth Borchardt
BACKGROUND: The American Society of Anesthesiologists (ASA) physical status is a universal classification system that helps clinicians to categorize their patients preoperatively. However, there is a lack of both inter-rater and intra-rater reliability among clinicians for the ASA physical status classification. Our study focuses on testing these reliabilities within pediatric anesthesia providers in the cancer setting. METHODS: In our retrospective observational study, a total of 1177 anesthesia records were reviewed...
February 13, 2018: Journal of Anesthesia
https://www.readbyqxmd.com/read/29441401/exercise-induced-fatigue-in-young-people-advances-and-future-perspectives
#11
REVIEW
Dimitrios A Patikas, Craig A Williams, Sébastien Ratel
PURPOSE: In recent decades, the interest for exercise-induced fatigue in youth has substantially increased, and the effects of growth on the peripheral (muscular) and central (neural) mechanisms underpinning differences in neuromuscular fatigue between healthy children and adults have been described more extensively. The purpose of this review is to retrieve, report, and analyse the findings of studies comparing neuromuscular fatigue between children and adults. Objective measures of the evaluation of the physiological mechanisms are discussed...
February 13, 2018: European Journal of Applied Physiology
https://www.readbyqxmd.com/read/29441204/relationships-between-compulsive-exercise-quality-of-life-psychological-distress-and-motivation-to-change-in-adults-with-anorexia-nervosa
#12
Sarah Young, Stephen Touyz, Caroline Meyer, Jon Arcelus, Paul Rhodes, Sloane Madden, Kathleen Pike, Evelyn Attia, Ross D Crosby, Phillipa Hay
Background: For people with anorexia nervosa (AN), compulsive exercise is characterized by extreme concerns about the perceived negative consequences of stopping/reducing exercise, dysregulation of affect, and inflexible exercise routines. It is associated with increased eating disorder psychopathology and poor clinical outcome. However, its relationships with two important clinical issues, quality of life (QoL) and motivation to change, are currently unknown. This study aimed to assess the cross-sectional relationships between compulsive exercise, QoL, psychological distress (anxiety and depressive symptoms, and obsessive-compulsive traits) and motivation to change in patients with AN...
2018: Journal of Eating Disorders
https://www.readbyqxmd.com/read/29441202/pulse-wave-doppler-ultrasound-of-testicular-arteries-and-their-relationship-with-semen-characteristics-in-healthy-bulls
#13
Alessia Gloria, Augusto Carluccio, Laura Wegher, Domenico Robbe, Claudio Valorz, Alberto Contri
Background: Semen evaluation is used to estimate the testicular function. In bulls, the spermatozoa present in the ejaculate are the result of a process that begun more than 2 mo earlier, bequeathing a delayed depiction of the actual function of the testis. Since testis vascularization might be critical for the gonad function, selected pulse wave Doppler ultrasound parameters were assessed in this study, for instance the peak systolic velocity, the end diastolic velocity and the resistive index of the testicular artery along the spermatic cord, the marginal portion of the testicular artery and the intratesticular branches of the testicular artery both in healthy adult and young bulls...
2018: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/29441182/pediatric-cardiac-anamnesis-prevention-of-additional-diagnostic-tests
#14
REVIEW
Izet Masic, Zijo Begic, Nabil Naser, Edin Begic
Pediatrics is defined as the science of a healthy and sick child from birth to end of adolescence. Diseases of the cardiovascular system are the leading causes of mortality in adults, with frequent onset in childhood. The cardiologic examination starts with anamnesis in a pleasant atmosphere, refined space, enough time and patience, detailed measurements, and preferably a noncrying child. Anamnesis, regardless of the development of diagnostic procedures, still constitutes the basis of every clinical examination...
2018: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29441170/management-of-traumatic-brain-injury-patients
#15
REVIEW
Hari Hara Dash, Siddharth Chavali
Traumatic brain injury (TBI) has been called the 'silent epidemic' of modern times, and is the leading cause of mortality and morbidity in children and young adults in both developed and developing nations worldwide. In recent years, the treatment of TBI has undergone a paradigm shift. The management of severe TBI is ideally based on protocol-based guidelines provided by the Brain Trauma Foundation. The aims and objectives of its management are prophylaxis and prompt management of intracranial hypertension and secondary brain injury, maintenance of cerebral perfusion pressure, and ensuring adequate oxygen delivery to injured brain tissue...
February 2018: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/29441008/diagnosis-and-treatment-of-cerebral-venous-thrombosis-a-review
#16
REVIEW
Yaxi Luo, Xin Tian, Xuefeng Wang
Cerebral venous thrombosis (CVT), also called cerebral venous sinus thrombosis (CVST), is a cerebrovascular disease with diverse clinical manifestations that often affects young adults, women of childbearing age, and children. It's most common clinical manifestations are headache, seizures, altered consciousness, and neurological focal signs on physical examination. CVT can manifest as a single symptom, or it can present as a syndrome consisting of multiple symptoms. This non-specific clinical picture makes diagnosing CVT difficult...
2018: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/29440880/comparison-of-three-tools-for-predicting-primary-osteoporosis-in-an-elderly-male-population-in-beijing-a-cross-sectional-study
#17
XiaoDong Zhang, JiSheng Lin, Yong Yang, Hao Wu, Yongjin Li, Xiuquan Yang, Qi Fei
Purpose: In this cross-sectional study, three clinical tools, the Osteoporosis Self-Assessment Tool for Asians (OSTA), Fracture Risk Assessment Tool (FRAX) without bone mineral density (BMD), and body mass index (BMI), for predicting primary osteoporosis (OP) were compared and ideal thresholds for omission of screening BMD were proposed in a community-dwelling elderly Han Beijing male population. Patients and methods: A total of 1,349 community-dwelling elderly Han Beijing males aged ≥50 years were enrolled in this study...
2018: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29440857/eruptive-vellus-hair-cyst-an-uncommon-and-underdiagnosed-entity
#18
Priyanka Anand, Namrata Sarin, Rachita Misri, V K Khurana
Eruptive vellus hair cyst (EVHC) is a rare follicular developmental abnormality of the vellus hair follicles. They are usually seen in children, adolescents, or young adults and manifest as reddish-brown smooth papules most commonly involving the chest, limbs, and abdomen. An 18-year-old male presented with asymptomatic papules on the trunk and flexor aspect of both forearms for the past 2 years. There was no family history of similar lesions. His medical history was also not contributory. A clinical diagnosis of steatocystoma multiplex and chronic folliculitis was given, and a punch biopsy from the papule was performed and sent for histopathological examination...
January 2018: International Journal of Trichology
https://www.readbyqxmd.com/read/29440328/evaluation-of-california-s-tobacco-21-law
#19
Xueying Zhang, Tam D Vuong, Elizabeth Andersen-Rodgers, April Roeseler
INTRODUCTION: California's law raising the minimum tobacco sales age to 21 went into effect on 9 June 2016. This law, known as 'Tobacco 21' or 'T21', also expanded the definition of tobacco to include electronic smoking devices. This paper describes the T21 evaluation plan and initial evaluation results. METHODS: An evaluation plan and logic model were created to evaluate T21. A tobacco retailer poll was conducted 7 months after the law went into effect to assess awareness, support and implementation; an online survey of California adults was fielded to provide data on tobacco use and attitudinal changes before and after T21 implementation; and tobacco purchase surveys were conducted to assess the retailer violation rate (RVR)...
February 13, 2018: Tobacco Control
https://www.readbyqxmd.com/read/29440190/a-model-linking-sickle-cell-hemoglobinopathies-and-smarcb1-loss-in-renal-medullary-carcinoma
#20
Pavlos Msaouel, Nizar M Tannir, Cheryl Lyn Walker
Renal medullary carcinoma (RMC) is a highly aggressive malignancy that predominantly afflicts young adults and adolescents with sickle hemoglobinopathies. It is characterized by complete loss of expression of the chromatin remodeler and tumor suppressor SMARCB1. Despite therapy, the outcomes of patients with RMC remain very poor, highlighting the need to understand the etiology of this cancer, and develop new diagnostic, preventive, and therapeutic strategies. A key knowledge gap in RMC biology is why sickle hemoglobinopathies predispose to the development of this cancer...
February 12, 2018: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
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