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https://www.readbyqxmd.com/read/28089189/exploring-the-brain-bases-of-dreaming-commentary-on-beyond-the-neuropsychology-of-dreaming-insights-into-the-neural-basis-of-dreaming-with-new-techniques-of-sleep-recording-and-analysis-sleep-medicine-reviews
#1
EDITORIAL
https://www.readbyqxmd.com/read/28063022/identification-of-a-syndrome-class-of-neuropsychiatric-adverse-reactions-to-mefloquine-from-latent-class-modeling-of-fda-adverse-event-reporting-system-data
#2
Remington L Nevin, Jeannie-Marie Leoutsakos
INTRODUCTION: Although mefloquine use is known to be associated with a risk of severe neuropsychiatric adverse reactions that are often preceded by prodromal symptoms, specific combinations of neurologic or psychiatric reactions associated with mefloquine use are not well described in the literature. This study sought to identify a distinct neuropsychiatric syndrome class associated with mefloquine use in reports of adverse events. METHODS: Latent class modeling of US Food and Drug Administration Adverse Event Reporting System (FAERS) data was performed using indicators defined by the Medical Dictionary for Regulatory Activities neurologic and psychiatric high-level group terms, in a study dataset of FAERS reports (n = 5332) of reactions to common antimalarial drugs...
January 6, 2017: Drugs in R&D
https://www.readbyqxmd.com/read/28007991/genetic-inactivation-of-glutamate-neurons-in-the-rat-sublaterodorsal-tegmental-nucleus-recapitulates-rem-sleep-behaviour-disorder
#3
Sara Valencia Garcia, Paul-Antoine Libourel, Michael Lazarus, Daniela Grassi, Pierre-Hervé Luppi, Patrice Fort
Idiopathic REM sleep behaviour disorder is characterized by the enactment of violent dreams during paradoxical (REM) sleep in the absence of normal muscle atonia. Accumulating clinical and experimental data suggest that REM sleep behaviour disorder might be due to the neurodegeneration of glutamate neurons involved in paradoxical sleep and located within the pontine sublaterodorsal tegmental nucleus. The purpose of the present work was thus to functionally determine first, the role of glutamate sublaterodorsal tegmental nucleus neurons in paradoxical sleep and second, whether their genetic inactivation is sufficient for recapitulating REM sleep behaviour disorder in rats...
December 21, 2016: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28005464/improvement-of-darts-performance-following-lucid-dream-practice-depends-on-the-number-of-distractions-while-rehearsing-within-the-dream-a-sleep-laboratory-pilot-study
#4
Melanie Schädlich, Daniel Erlacher, Michael Schredl
In a lucid dream, the dreamer is aware of the dream state and can deliberately practice motor skills. Two field studies indicated that lucid dream practice can improve waking performance in simple motor tasks. The present pilot study investigated the effect of lucid dream practice in a controlled sleep laboratory setting, using a pre-post design with dart throwing in the evening and morning. The experimental group practiced darts in lucid dreams. Because some participants were distracted during lucid dream practice, the group was divided into lucid dreamers with few (n = 4) and many distractions (n = 5)...
December 22, 2016: Journal of Sports Sciences
https://www.readbyqxmd.com/read/27998373/sleep-quality-in-an-adult-american-indian-community-sample
#5
Cindy L Ehlers, Derek N Wills, Philip Lau, David A Gilder
STUDY OBJECTIVES: Epidemiological studies have found that insufficient sleep (< 7 h/night) is more common among American Indians/Alaska Natives (AI/AN). In this study we sought to identify specific demographic, clinical, and cultural factors that may be associated with reduced sleep quality in an American Indian community sample. METHODS: Information on demography along with personal medical, psychiatric, and drinking history was obtained using the Semi-Structured Assessment for the Genetics of Alcoholism (SSAGA)...
December 16, 2016: Journal of Clinical Sleep Medicine: JCSM: Official Publication of the American Academy of Sleep Medicine
https://www.readbyqxmd.com/read/27965397/rem-sleep-behaviour-disorder-prodromal-and-mechanistic-insights-for-parkinson-s-disease
#6
REVIEW
Anand Tekriwal, Drew S Kern, Jean Tsai, Nuri F Ince, Jianping Wu, John A Thompson, Aviva Abosch
Rapid eye movement (REM) sleep behaviour disorder (RBD) is characterised by complex motor enactment of dreams and is a potential prodromal marker of Parkinson's disease (PD). Of note, patients with PD observed during RBD episodes exhibit improved motor function, relative to baseline states during wake periods. Here, we review recent epidemiological and mechanistic findings supporting the prodromal value of RBD for PD, incorporating clinical and electrophysiological studies. Explanations for the improved motor function during RBD episodes are evaluated in light of recent publications...
December 13, 2016: Journal of Neurology, Neurosurgery, and Psychiatry
https://www.readbyqxmd.com/read/27923426/periodic-limb-movements-during-sleep-mimicking-rem-sleep-behavior-disorder
#7
Carles Gaig, Alex Iranzo, Montserrat Pujo, Hernando Perez, Joan Santamaria
STUDY OBJECTIVE: To describe a group of patients referredbecause of abnormal sleep behaviors that were suggestive ofREM sleep behavior disorder (RBD) in whom videopolysomnographyruled out RBD and showed the reportedbehaviors associated with vigorous periodic limb movementsduring sleep (PLMS). METHODS: Clinical history and video-polysomnography reviewof patients identified during routine visits in a sleepcenter. RESULTS: Patients were fifteen men and two women with a median age of 66 (range 48-77) years...
November 28, 2016: Sleep
https://www.readbyqxmd.com/read/27881921/the-occurrence-and-predictive-factors-of-sleep-paralysis-in-university-students
#8
Monika Lišková, Denisa Janečková, Lucie Klůzová Kráčmarová, Karolína Mladá, Jitka Bušková
The aim of the present study was to assess the occurrence and predictive factors of sleep paralysis (SP) in Czech university students. Our sample included 606 students who had experienced at least one episode of SP. The participants completed an online battery of questionnaires involving questionnaires focused on describing their sleep habits and SP episodes, the 18-item Boundary Questionnaire (BQ-18), the Modified Tellegen Absorption Scale (MODTAS), the Dissociative Experience Scale Taxon, the Beck Depression Inventory II and the State-Trait Anxiety Inventory...
2016: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/27837575/dreams-in-ancient-greek-medicine
#9
K Laios, M M Moschos, E Koukaki, E Vasilopoulos, M Karamanou, M-I Kontaxaki, G Androutsos
Dreams preoccupied the Greek and Roman world in antiquity, therefore they had a prominent role in social, philosophical, religious, historical and political life of those times. They were considered as omens and prophetic signs of future events in private and public life, and that was particularly accentuated when elements of actions which took place in the plot of dreams were associated directly or indirectly with real events. This is why it was important to use them in divination, and helped the growth of superstition and folklore believes...
July 2016: Psychiatrikē, Psychiatriki
https://www.readbyqxmd.com/read/27828694/efficacy-of-prazosin-in-posttraumatic-stress-disorder-a-systematic-review-and-meta-analysis
#10
Balwinder Singh, Andrew J Hughes, Gaurav Mehta, Patricia J Erwin, Ajay K Parsaik
OBJECTIVE: To consolidate the evidence from the literature to evaluate the role of prazosin in the treatment of posttraumatic stress disorder (PTSD). DATA SOURCES: Major databases, including PubMed, Ovid EMBASE, Ovid Cochrane Central Register of Controlled Trials, Ovid Cochrane Database of Systematic Reviews, Ovid PsycINFO, and Scopus, were searched through August 2015 for studies reporting the role of prazosin in the treatment of PTSD with no language constraints...
July 28, 2016: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/27822278/prazosin-for-trauma-nightmares-and-sleep-disturbances-in-combat-veterans-with-post-traumatic-stress-disorder
#11
Habibolah Khazaie, Marzie Nasouri, Mohammad Rasoul Ghadami
BACKGROUND: Prazosin is significantly effective to reduce sleep disturbance and trauma nightmare in patients with post-traumatic stress disorder (PTSD); however, results of different studies were evaluated. OBJECTIVES: The current randomized clinical trial aimed to assess the effects of prazosin on sleep parameters and nightmares among veterans with chronic PTSD. MATERIALS AND METHODS: Thirty-two veterans with chronic war-induced PTSD and distressing nightmares were randomized into prazosin and placebo groups for eight weeks...
September 2016: Iranian Journal of Psychiatry and Behavioral Sciences
https://www.readbyqxmd.com/read/27806675/investigation-of-maternal-psychopathological-symptoms-dream-anxiety-and-insomnia-in-preeclampsia
#12
Orkun Cetin, Pınar Guzel Ozdemir, Zehra Kurdoglu, Hanım Guler Sahin
PURPOSE: The aim of the current study was to investigate the psychopathological symptoms, psycho-emotional state, dream anxiety, and insomnia in healthy, mild and severe preeclamptic postpartum women and their relation to the severity of preeclampsia. MATERIALS AND METHODS: This observational study included forty-five healthy, 41 mild preeclamptic and 44 severe preeclamptic postpartum women. The 90-item Symptom Checklist Revised, Hospital Anxiety and Depression Scale, Insomnia Severity Index, and Van Dream Anxiety Scale were used to evaluate the psychopathological symptoms, psycho-emotional state, insomnia, and dream anxiety of the participants after delivery...
November 2, 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27802458/problems-associated-with-use-of-mobile-devices-in-the-sleep-environment-streaming-instead-of-dreaming
#13
Charles A Czeisler, Theresa L Shanahan
No abstract text is available yet for this article.
December 1, 2016: JAMA Pediatrics
https://www.readbyqxmd.com/read/27765517/does-consciousness-disappear-in-dreamless-sleep
#14
REVIEW
Jennifer M Windt, Tore Nielsen, Evan Thompson
Consciousness is often said to disappear in deep, dreamless sleep. We argue that this assumption is oversimplified. Unless dreamless sleep is defined as unconscious from the outset there are good empirical and theoretical reasons for saying that a range of different types of sleep experience, some of which are distinct from dreaming, can occur in all stages of sleep. We introduce a novel taxonomy for describing different kinds of dreamless sleep experiences and suggest research methods for their investigation...
December 2016: Trends in Cognitive Sciences
https://www.readbyqxmd.com/read/27757562/a-case-series-of-rem-sleep-behavior-disorder-in-pure-autonomic-failure
#15
Mitchell G Miglis, Srikanth Muppidi, Emmanuel During, Safwan Jaradeh
PURPOSE: Data on the prevalence of RBD in patients with PAF are limited, with discrepancies in the literature regarding prevalence. We aimed to provide further data on this association with a series of eight patients with PAF. METHODS: We reviewed the electronic medical records of all patients seen at the Stanford neurology clinics from 2012 to 2016 who were given a provisional diagnosis of PAF (343 patients), and further screened by procedure codes to identify those patients who underwent both attended video-polysomonography and autonomic testing (18 patients), and met strict exclusionary criteria (8 patients)...
October 18, 2016: Clinical Autonomic Research: Official Journal of the Clinical Autonomic Research Society
https://www.readbyqxmd.com/read/27752878/treatment-of-rem-sleep-behavior-disorder
#16
Youngsin Jung, Erik K St Louis
REM sleep behavior disorder (RBD) is a common parasomnia disorder affecting between 1 and 7 % of community-dwelling adults, most frequently older adults. RBD is characterized by nocturnal complex motor behavior and polysomnographic REM sleep without atonia. RBD is strongly associated with synucleinopathy neurodegeneration. The approach to RBD management is currently twofold: symptomatic treatment to prevent injury and prognostic counseling and longitudinal follow-up surveillance for phenoconversion toward overt neurodegenerative disorders...
November 2016: Current Treatment Options in Neurology
https://www.readbyqxmd.com/read/27718407/a-template-model-of-embodiment-while-dreaming-proposal-of-a-mini-me
#17
Judith Koppehele-Gossel, Ansgar Klimke, Karin Schermelleh-Engel, Ursula Voss
Dreams are usually centered around a dream self capable of tasks generally impossible in waking, e.g. flying or walking through walls. Moreover, the bodily dream self appears relatively stable and insensitive to changes of the embodied wake self, raising the question of whether and to what extent the dream self is embodied. To further explore its determinants, we tested whether the dream self would be affected by either pre-sleep focused attention to a body part or by its experimental alteration during the day...
November 2016: Consciousness and Cognition
https://www.readbyqxmd.com/read/27718406/crossing-the-invisible-line-de-differentiation-of-wake-sleep-and-dreaming-may-engender-both-creative-insight-and-psychopathology
#18
Sue Llewellyn
Writing about dreaming, the poet Raymond Carver said "I feel as if I've crossed some kind of invisible line". In creative people, the "line" between wake, dreaming and psychopathology may be porous, engendering a de-differentiated, super-critical, hybrid state. Evidence exists for a relationship between creativity and psychopathology but its nature has been elusive. De-differentiation between wake, sleep and dreaming may be the common substrate, as dream-like cognition pervades wake and wake-like neurophysiology suffuses sleep...
November 2016: Consciousness and Cognition
https://www.readbyqxmd.com/read/27712640/importance-of-rapid-eye-movement-sleep-behavior-disorder-to-the-primary-care-physician
#19
REVIEW
Stuart J McCarter, Michael J Howell
Sleep disorders and neurodegenerative diseases are commonly encountered in primary care. A common, but underdiagnosed sleep disorder, rapid eye movement sleep behavior disorder (RBD), is highly associated with Parkinson disease and related disorders. Rapid eye movement sleep behavior disorder is common. It is estimated to affect 0.5% of the general population and more than 7% of individuals older than 60 years; however, most cases go unrecognized. Rapid eye movement sleep behavior disorder presents as dream enactment, often with patients thrashing, punching, and kicking while they are sleeping...
October 2016: Mayo Clinic Proceedings
https://www.readbyqxmd.com/read/27703108/-the-function-of-rem-sleep-implications-from-transgenic-mouse-models
#20
Mitsuaki Kashiwagi, Yu Hayashi
Our sleep is composed of rapid eye movement (REM) sleep and non-REM (NREM) sleep. REM sleep is the major source of dreams, whereas synchronous cortical oscillations, called slow waves, are observed during NREM sleep. Both stages are unique to certain vertebrate species, and therefore, REM and NREM sleep are thought to be involved in higher-order brain functions. While several studies have revealed the importance of NREM sleep in growth hormone secretion, memory consolidation and brain metabolite clearance, the functions of REM sleep are currently almost totally unknown...
October 2016: Brain and Nerve, Shinkei Kenkyū No Shinpo
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