Sam Parnia, Tara Keshavarz Shirazi, Jignesh Patel, Linh Tran, Niraj Sinha, Caitlin O'Neill, Emma Roellke, Amanda Mengotto, Shannon Findlay, Michael McBrine, Rebecca Spiegel, Thaddeus Tarpey, Elise Huppert, Ian Jaffe, Anelly M Gonzales, Jing Xu, Emmeline Koopman, Gavin D Perkins, Alain Vuylsteke, Benjamin M Bloom, Heather Jarman, Hiu Nam Tong, Louisa Chan, Michael Lyaker, Matthew Thomas, Veselin Velchev, Charles B Cairns, Rahul Sharma, Erik Kulstad, Elizabeth Scherer, Terence O'Keeffe, Mahtab Foroozesh, Olumayowa Abe, Chinwe Ogedegbe, Amira Girgis, Deepak Pradhan, Charles D Deakin
INTRODUCTION: Cognitive activity and awareness during cardiac arrest (CA) are reported but ill understood. This first of a kind study examined consciousness and its underlying electrocortical biomarkers during cardiopulmonary resuscitation (CPR). METHODS: In a prospective 25-site in-hospital study, we incorporated a) independent audiovisual testing of awareness, including explicit and implicit learning using a computer and headphones, with b) continuous real-time electroencephalography(EEG) and cerebral oxygenation(rSO2 ) monitoring into CPR during in-hospital CA (IHCA)...
October 2023: Resuscitation